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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Trabectedin Induces Synthetic Lethality via the p53-Dependent Apoptotic Pathway in Ovarian Cancer Cells Without BRCA Mutations When Used in Combination with Niraparib | This study investigated whether combining niraparib and trabectedin in BRCA-proficient epithelial ovarian cancer induces deficiencies in ssDNA break repair and dsDNA homologous recombination, leading to synthetic lethality. A2780 and SKOV3 ovarian cancer cell lines were treated with niraparib and trabectedin. Cell viability was assessed using CCK-8 assays, while RT-qPCR and Western blot analyzed the expression of DNA repair and apoptosis-related genes. Apoptosis was evaluated via Annexin V/PI assays. The combination therapy exhibited a synergistic effect on A2780 cells but not on SKOV3 cells. Treatment reduced BRCA1, BRCA2, RAD51, PARP1, and PARP2 expression, indicating impaired DNA repair. gamma-H2AX levels increased, suggesting DNA damage. The therapy also upregulated p53, PUMA, NOXA, BAX, BAK, and p21, promoting p53-mediated apoptosis and cell cycle arrest. Apoptosis induction was confirmed via Annexin V/PI assays. Silencing p53 with siRNA abolished all synergistic effects in A2780 cells. Niraparib and trabectedin combination therapy impairs DNA repair in BRCA-proficient ovarian cancer, leading to synthetic lethality through p53-dependent apoptosis. | Kang, Bongkyun; Lee, Sun-Jae; Seol, Ki Ho; Jeong, Yoon Young; Choi, Jung-Hye; Choi, Bo-Hyun; Ryu, Jung Min; Choi, Youn Seok | Kyungpook Natl Univ, Coll Nat Sci, Dept Chem, Daegu 41944, South Korea; Daegu Catholic Univ, Sch Med, Dept Pathol, Daegu 42472, South Korea; Daegu Catholic Univ, Sch Med, Dept Radiat Oncol, Daegu 42472, South Korea; Daegu Catholic Univ, Sch Med, Dept Obstet & Gynecol, Daegu 42472, South Korea; Kyung Hee Univ, Dept Biomed & Pharmaceut Sci, Seoul 02447, South Korea; Daegu Catholic Univ, Sch Med, Dept Pharmacol, Daegu 42472, South Korea | 59308890800; 55597207600; 56096209000; 57231497500; 35953529000; 55203468900; 57204547720; 55507132200 | xmas84@gmail.com; pathosjlee@cu.ac.kr; khseol@cu.ac.kr; nning@cu.ac.kr; jchoi@khu.ac.kr; bchoi@cu.ac.kr; medgirl1231@cu.ac.kr; drcys@cu.ac.kr; | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | INT J MOL SCI | 1661-6596 | 1422-0067 | 26 | 7 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2024 | 4.9 | 22.4 | 0 | 2025-05-07 | 0 | 0 | ovarian carcinoma; poly (ADP-ribose) polymerase inhibitor; trabectedin; synthetic lethality; homologous recombination deficiency | HOMOLOGOUS RECOMBINATION; NUCLEOTIDE-EXCISION; MAINTENANCE THERAPY; SOMATIC MUTATIONS; ECTEINASCIDIN-743; INHIBITOR; MECHANISM; ET-743 | homologous recombination deficiency; ovarian carcinoma; poly (ADP-ribose) polymerase inhibitor; synthetic lethality; trabectedin | Apoptosis; BRCA1 Protein; BRCA2 Protein; Cell Line, Tumor; Cell Survival; DNA Repair; Drug Synergism; Female; Humans; Indazoles; Mutation; Ovarian Neoplasms; Piperidines; Synthetic Lethal Mutations; Trabectedin; Tumor Suppressor Protein p53; BRCA1 protein; BRCA2 protein; histone H2AX; lipocortin 5; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 2; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor; niraparib; protein Bax; protein Noxa; protein p21; protein p53; PUMA protein; Rad51 protein; small interfering RNA; trabectedin; BRCA1 protein; BRCA1 protein, human; BRCA2 protein; BRCA2 protein, human; indazole derivative; niraparib; piperidine derivative; protein p53; TP53 protein, human; trabectedin; A2780 cell line; apoptosis; Article; cell cycle arrest; cell viability; controlled study; DNA damage; DNA repair; drug interaction; female; homologous recombination; human; human cell; ovarian cancer cell line; ovary cancer; proapoptotic activity; real time polymerase chain reaction; single strand break repair; SK-OV-3 cell line; synthetic lethality; treatment duration; upregulation; Western blotting; cell survival; drug effect; drug potentiation; drug therapy; genetics; metabolism; mutation; ovary tumor; pathology; synthetic lethal mutation; tumor cell line | English | 2025 | 2025-03-24 | 10.3390/ijms26072921 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Trichostatin A-Induced Epigenetic Modifications and Their Influence on the Development of Porcine Cloned Embryos Derived from Bone Marrow-Mesenchymal Stem Cells | Abnormal epigenetic reprogramming of nuclear-transferred (NT) embryos leads to the limited efficiency of producing cloned animals. Trichostatin A (TSA), a histone deacetylase inhibitor, improves NT embryo development, but its role in histone acetylation in porcine embryos cloned with mesenchymal stem cells (MSCs) is not fully understood. This study aimed to compare the effects of TSA on embryo development, histone acetylation patterns, and key epigenetic-related genes between in vitro fertilization (IVF), NT-MSC, and 40 nM TSA-treated NT-MSC (T-NT-MSC). The results demonstrated an increase in the blastocyst rate from 13.7% to 32.5% in the T-NT-MSC, and the transcription levels of CDX2, NANOG, and IGF2R were significantly elevated in T-NT-MSC compared to NT-MSC. TSA treatment also led to increased fluorescence intensity of acH3K9 and acH3K18 during early embryo development but did not differ in acH4K12 levels. The expression of epigenetic-related genes (HDAC1, HDAC2, CBP, p300, DNMT3a, and DNMT1) in early pre-implantation embryos followed a pattern similar to IVF embryos. In conclusion, TSA treatment improves the in vitro development of porcine embryos cloned with MSCs by increasing histone acetylation, modifying chromatin structure, and enhancing the expression of key genes, resulting in profiles similar to those of IVF embryos. | Lee, Seung-Chan; Lee, Won-Jae; Son, Young-Bum; Jin, Yeung Bae; Lee, Hyeon-Jeong; Bok, Eunyeong; Lee, Sangyeob; Lee, Sang-Yun; Jo, Chan-Hee; Kim, Tae-Seok; Hong, Chae-Yeon; Kang, Seo-Yoon; Rho, Gyu-Jin; Choe, Yong-Ho; Lee, Sung-Lim | Gyeongsang Natl Univ, Coll Vet Med, Jinju 52828, South Korea; Apures Inc, Cent Res Ctr, Pyeongtaek Si 17792, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Chonnam Natl Univ, Coll Vet Med, Dept Obstet, 300 Yonbongdong, Gwangju 61186, South Korea; Rural Dev Adm, Natl Inst Anim Sci, Div Anim Dis & Hlth, Wanju 55365, South Korea; Gyeongsang Natl Univ, Res Inst Life Sci, Jinju 52828, South Korea | bok, eun yeong/MYS-4388-2025 | 56643622900; 57205486455; 57197735518; 59681564200; 57202973938; 57221645701; 57221648858; 57216913305; 57221808828; 58412692900; 58411924300; 59681304900; 6603725057; 57202927556; 16678898100 | yhchoe@gnu.ac.kr; sllee@gnu.ac.kr; | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | INT J MOL SCI | 1661-6596 | 1422-0067 | 26 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2024 | 4.9 | 22.4 | 0 | 2025-05-07 | 0 | 0 | porcine; nuclear transfer; trichostatin A; histone acetylation; epigenetic change | IN-VITRO DEVELOPMENT; HISTONE DEACETYLASE INHIBITOR; NUCLEAR TRANSFER; GENE-EXPRESSION; MINIATURE PIG; SIGNIFICANT IMPROVEMENT; CLONING EFFICIENCY; DNA METHYLATION; ACETYLATION; VIABILITY | epigenetic change; histone acetylation; nuclear transfer; porcine; trichostatin A | Acetylation; Animals; Blastocyst; Bone Marrow Cells; Cloning, Organism; Embryonic Development; Epigenesis, Genetic; Fertilization in Vitro; Gene Expression Regulation, Developmental; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mesenchymal Stem Cells; Nuclear Transfer Techniques; Swine; DNA (cytosine 5) methyltransferase 1; DNA methyltransferase 3A; E1A associated p300 protein; histone; histone deacetylase 1; histone deacetylase 2; transcription factor Cdx2; transcription factor NANOG; trichostatin A; histone; histone deacetylase inhibitor; hydroxamic acid; animal cell; animal experiment; Article; blastocyst; bone marrow mesenchymal stem cell; chromatin structure; cloning; controlled study; embryo; embryo development; epigenetic modification; fluorescence intensity; genetic transcription; histone acetylation; in vitro fertilization; in vitro study; molecular imprinting; nonhuman; pluripotent stem cell; porcine embryo; acetylation; animal; bone marrow cell; cell nucleus transplantation; cytology; drug effect; gene expression regulation; genetic epigenesis; genetics; mesenchymal stem cell; metabolism; pig; procedures | English | 2025 | 2025-03 | 10.3390/ijms26052359 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Two-step polymerization for tailored donor-acceptor interactions driving efficient hydrogen evolution in visible-light photocatalysts | The development of materials for organic solar cells has made significant strides through the strategic combination of diverse donor structures with acceptor units in polymer backbones. In contrast, semiconducting polymers for photocatalytic hydrogen evolution have primarily focused on acceptor moieties, with limited exploration of donor contributions, primarily owing to the emphasis on designing active sites for proton reduction in inorganic catalysts. To investigate the impact of highly electron-donating moieties on photocatalytic performance, we designed and synthesized benzothiadiazole (BT)-based polymers with randomly incorporated benzodithiophene (BDT) and fluorene units via a streamlined one-pot Stille-Suzuki two-step polymerization. Comprehensive molecular characterization and optical spectroscopic analyses confirmed the successful synthesis of the target polymers. Photocatalytic hydrogen evolution studies, supported by photophysical and spectroscopic investigations, demonstrated that optimizing the proportion of BDT units in the polymer backbone enhances hydrogen evolution rates significantly. Additionally, comparative analyses further highlighted the distinct differences in the photocatalytic efficiency between the BDT and fluorene donor units, providing critical insights into their functional roles. This work underscores the potential of advancing polymer photocatalysts by fine-tuning donor-acceptor interactions through optimization of donor moiety composition, offering a robust framework for achieving superior photocatalytic performance. © 2025 RSC. | Jung, Wooteak; An, Sanghyeok; Ham, Gayoung; Kim, Chanhyeok; Lee, Soyeon; Yang, Jiwoong; Chung, Dae Sung; Cha, Hyojung; Park, Taiho | Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Gyeongbuk, Pohang, 37673, South Korea; Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Gyeongbuk, Pohang, 37673, South Korea; School of Energy Engineering, Kyungpook National University, Daehak-ro 80, Buk-gu, Daegu, 41566, South Korea; Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Gyeongbuk, Pohang, 37673, South Korea; Department of Energy Science and Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, South Korea; Department of Energy Science and Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, South Korea, Energy Science and Engineering Research Center, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, South Korea; Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Gyeongbuk, Pohang, 37673, South Korea; School of Energy Engineering, Kyungpook National University, Daehak-ro 80, Buk-gu, Daegu, 41566, South Korea; Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Gyeongbuk, Pohang, 37673, South Korea | 57578074400; 57226353850; 58506766600; 58043221600; 59731365900; 55325747800; 15019094800; 35885242200; 8412341200 | dchung@postech.ac.kr; hcha@knu.ac.kr; | EES Catalysis | EES CATAL | N/A | 2753-801X | ESCI | CHEMISTRY, PHYSICAL | 2024 | 8.1 | 22.4 | 0 | 2025-05-07 | 0 | English | Article in press | 2025 | 10.1039/d5ey00035a | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | Transcriptome Analysis of HNSCC by Aggregatibacter actinomycetemcomitans Extracellular Vesicles | ObjectivesThe role of extracellular vesicles (EVs), also known as outer membrane vesicles (OMVs), secreted by oral bacteria in the progression of head and neck squamous cell carcinomas (HNSCCs), is largely unexplored. This study aimed to investigate the influence of bacterial EVs, specifically those derived from Aggregatibacter actinomycetemcomitans (Aa), on the progression of HNSCC.Materials and MethodsFaDu and UMSCC1 cell lines were treated with Aa-derived EVs, and oncogenic activities were assessed. Comprehensive cellular and RNA-sequencing transcriptome analyses were conducted to assess the impact of these EVs on cell cycle progression and gene expression.ResultsOur findings reveal that Aa-derived EVs accelerate cell cycle progression through the S and G2 phases and enhance invasion in HNSCC cell lines. RNA-sequencing analysis showed that Aa-derived EVs exert a more significant effect on general transcript expression than on microRNA profiles, except for miR-146a, which is recognized as a key factor in both carcinogenesis and immune modulation.ConclusionsBacterial EVs, particularly from periodontal pathogens like Aa, are significant modulators within the oral cancer environment, potentially affecting cellular behavior and gene expression profiles. This study highlights the complex relationship between periodontal health and oral carcinogenesis, emphasizing the significant role of bacterial EVs in HNSCC progression. | Ha, Jae Yeong; Choi, Song-Yi; Kim, Suk-Jeong; Seog, Kristen Jin; Hong, Su-Hyung; Lee, Heon-Jin | Kyungpook Natl Univ, Sch Dent, Dept Microbiol & Immunol, Daegu, South Korea; Kyungpook Natl Univ, Craniofacial Nerve Bone Network Res Ctr, Daegu, South Korea | 57220581488; 57210356632; 58555644600; 57222135291; 8691449100; 36462383000 | heonlee@knu.ac.kr; | ORAL DISEASES | ORAL DIS | 1354-523X | 1601-0825 | 31 | 4 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE | 2024 | 2.9 | 22.5 | 0 | 2025-05-07 | 0 | 0 | extracellular vesicle; head and neck squamous cell carcinomas (HNSCCs); microRNA; oral cancer; periodontopathogen; RNA-seq | OUTER-MEMBRANE VESICLES; RNAS; PROGRESSION; GINGIVALIS; INVASION; STORIES; CELLS | extracellular vesicle; head and neck squamous cell carcinomas (HNSCCs); microRNA; oral cancer; periodontopathogen; RNA-seq | Aggregatibacter actinomycetemcomitans; Cell Cycle; Cell Line, Tumor; Extracellular Vesicles; Gene Expression Profiling; Head and Neck Neoplasms; Humans; MicroRNAs; Squamous Cell Carcinoma of Head and Neck; Transcriptome; microRNA; ribosome DNA; transcriptome; microRNA; transcriptome; Aggregatibacter actinomycetemcomitans; animal cell; animal experiment; animal model; Article; bacterium culture; cancer growth; cell cycle G2 phase; cell cycle progression; cell invasion; cell proliferation; cell viability; controlled study; exosome; FaDu cell line; female; gene expression; gene expression profiling; head and neck squamous cell carcinoma; human; human cell; immunocytochemistry; immunomodulation; mouse; mRNA expression level; nonhuman; real time reverse transcription polymerase chain reaction; RNA sequencing; transmission electron microscopy; UM-SCC-1 cell line; cell cycle; genetics; head and neck squamous cell carcinoma; head and neck tumor; metabolism; microbiology; pathology; tumor cell line | English | 2025 | 2025-04 | 10.1111/odi.15204 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | On the degenerate negative λ-binomial and Poisson random variables from degenerate special polynomials | In this paper, we investigate the theory and applications of negative lambda-binomial random variable with parameter $(r,p)$(r,p) and Poisson random variable with parameter $\alpha $alpha. In particular, we show that the expectation of rising factorial sequences or degenerate rising factorial sequences of negative lambda-binomial random variables or Poisson random variables are strongly related to Lah numbers, modified degenerate Lah-Bell polynomials, the Stirling numbers of the first kind and Bell polynomials. | Kwon, Jongkyum; Park, Sangbeom; Park, Jin-Woo | Gyeongsang Natl Univ, Dept Math Educ, Jinju, South Korea; Kyungpook Natl Univ, Dept Math, Daegu, South Korea; Daegu Univ, Dept Math Educ, Daegu 38453, South Korea | 55000770500; 57374873000; 56135574800 | a0417001@daegu.ac.kr; | MATHEMATICAL AND COMPUTER MODELLING OF DYNAMICAL SYSTEMS | MATH COMP MODEL DYN | 1387-3954 | 1744-5051 | 31 | 1 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;MATHEMATICS, APPLIED | 2024 | 1.8 | 22.6 | 0 | 2025-05-07 | 0 | 0 | negative lambda-binomial random variable with parameter (r,p); Poisson random variable with parameters (r,p); degenerate bell polynomials | degenerate bell polynomials; negative λ-binomial random variable with parameter (r,p); Poisson random variable with parameters (r,p) | Choquet integral; Poisson equation; Random variables; Bell polynomials; Degenerate bell polynomial; Negative λ-binomial random variable with parameter (r,p); Poisson random variable with parameter (r,p); Poisson random variables; Special polynomials; Stirling numbers of the first kinds; Polynomials | English | 2025 | 2025-12-31 | 10.1080/13873954.2025.2468712 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Some identities of Fubini numbers related to special numbers | In this paper, we examine the interconnections between Fubini numbers and a range of recently defined special numbers, including the Lah-Bell numbers, the Changhee numbers, and the Dahee numbers, along with several other established special numbers. We explore these relationships by analysing the generating functions associated with these numbers, which enables us to establish diverse formulae for Fubini numbers in relation to other special numbers. Additionally, we uncover new properties of Fubini numbers through this investigation. Furthermore, by employing formal power series of generating functions, we establish general identities for special numbers, thereby extending our understanding of their properties and relationships. Finally, we study the interconnections of the five special functions by observing the shape of functions. | Park, Jin-Woo; Park, Sangbeom; Wongsason, Patcharee; Kwon, Jongkyum | Daegu Univ, Dept Math Educ, Gyongsan, Gyeongbuk, South Korea; Kyungpook Natl Univ, Dept Math, Daegu, South Korea; Ubon Ratchathani Univ, Fac Sci, Dept Math Stat & Comp, Ubon Ratchathani, Thailand; Gyeongsang Natl Univ, Dept Math Educ, Jinju 52828, South Korea | 56135574800; 57374873000; 57216978047; 55000770500 | mathkjk26@gnu.ac.kr; | MATHEMATICAL AND COMPUTER MODELLING OF DYNAMICAL SYSTEMS | MATH COMP MODEL DYN | 1387-3954 | 1744-5051 | 31 | 1 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;MATHEMATICS, APPLIED | 2024 | 1.8 | 22.6 | 0 | 2025-05-07 | 0 | 0 | Fubini numbers; Lah numbers; Euler numbers; Changhee numbers; Lah-Bell numbers; Bell numbers; Frobenius-Euler numbers; Bernoulli numbers; Daehee numbers | BERNOULLI NUMBERS; POLYNOMIALS | Bell numbers; Bernoulli numbers; Changhee numbers; Daehee numbers; Euler numbers; Frobenius-Euler numbers; Fubini numbers; Lah numbers; Lah-Bell numbers | Number theory; Bell number; Bernoulli numbers; Changhee number; Daehee number; Euler numbers; Frobenii-euler number; Fubini number; Lah number; Lah-bell number | English | 2025 | 2025-12-31 | 10.1080/13873954.2025.2470823 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Synthesis and X-ray structure analysis of cytotoxic 2-picolylamino-type HfⁱV-bis-chelated complexes | Eight novel heteroleptic HfIV complexes containing differently substituted 2-picolylamino-bis-phenolate and 2,6-dipicolinic acid (Dipic) groups as chelating ligands were synthesized and characterized with yields higher than 80%. These [ONON] type HfIV complexes have good aqueous stability and potent anti-tumor activity against HeLa S3 (human cervical adenocarcinoma) and Hep G2 (human derived hepatoma) cells. In particular, the complexes demonstrated selective inhibitory activity against Hep G2 cells. The IC50 value of the most cytotoxic complex [L1HfIVDipic4-Cl] (0.9 +/- 0.4 mu M) was ten-fold higher than that of cisplatin (11.2 +/- 2.1 mu M) on Hep G2 cells, being the most cytotoxic anti-tumor HfIV complex to date. Furthermore, [L1HfIVDipic4-Cl] could inhibit tumor cell migration, induce reactive oxygen species generation (particularly HO center dot), loss of mitochondrial membrane potential and almost exclusive early apoptosis in HeLa S3 cells. [L1HfIVDipic4-Cl] exhibited rapid cellular uptake by HeLa S3 cells, and when in aqueous media, these HfIV complexes slowly hydrolyzed, releasing non-toxic phenolato ligands as the product of hydrolysis. Overall, these rare earth complexes, particularly [L1HfIVDipic4-Cl], show promising potential as novel anticancer agents with significant efficacy against human liver cancer cells and favorable selectivity profiles for further therapeutic development. | Zhao, Tiankun; Zhang, Qi; Zhao, Jialiu; Mei, Dongyu; Ma, Jing; Correia, Isabel; Yang, Zhongduo; Kim, Sa-Hyun; Huhn, Thomas | Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China; Inst Super Tecn, Ctr Quim Estrutural, Ave Rovisco Pais 1, P-1049001 Lisbon, Portugal; Inst Super Tecn, Inst Mol Sci, Dept Engn Quim, Ave Rovisco Pais 1, P-1049001 Lisbon, Portugal; Kyungpook Natl Univ, Dept Clin Lab Sci, Daegu 27136, South Korea; Univ Konstanz, Fachbereich Chem, Univ Str 10, D-78457 Constance, Germany | Correia, Isabel/AAH-6847-2021 | 56732292800; 58644977500; 59722951600; 59723562600; 59723562700; 7003557498; 55898980900; 59180848000; 12754466700 | tiankun.zhao@tecnico.ulisboa.pt; | DALTON TRANSACTIONS | DALTON T | 1477-9226 | 1477-9234 | 54 | 16 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR | 2024 | 3.3 | 22.6 | 0 | 2025-05-07 | 0 | 0 | TITANIUM(IV) COMPLEXES; SALAN; LIGANDS; POLYMERIZATION; METALLOCENE; TITANOCENE; ZIRCONIUM; TUMOR | Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Reactive Oxygen Species; Cell death; Cell membranes; Chelation; Cytotoxicity; Hydrolysis; Lanthanum compounds; Ligands; Mitochondria; antineoplastic agent; chelating agent; coordination compound; reactive oxygen metabolite; Acid groups; Chelated complex; Chelating ligands; Cytotoxic; Dipicolinic acids; HeLa S3 cells; Hep-g2 cells; Heteroleptic; Synthesised; X ray structure analysis; apoptosis; cell motion; cell proliferation; chemical structure; chemistry; drug effect; drug screening; HeLa cell line; Hep-G2 cell line; human; metabolism; mitochondrial membrane potential; synthesis; X ray crystallography; Tumors | English | 2025 | 2025-04-15 | 10.1039/d4dt02859g | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Aspalathin, a Primary Rooibos Flavonoid, Alleviates Mast Cell-Mediated Allergic Inflammation by the Inhibition of FcεRI Signaling Pathway | Mast cells are primary cells initiating allergic inflammation by the release of various allergic mediators, such as histamine and pro-inflammatory cytokines. Aspalathin (ASP) is the predominant flavonoid found exclusively in rooibos, an herb that has been traditionally used in allergy relief therapy. In the present study, we investigated the beneficial effects of ASP on mast cell-mediated allergic inflammation. For in vivo study, two well-known mast cell-mediated local and systemic allergic inflammation mouse models were used: passive cutaneous anaphylaxis (PCA) and active systemic anaphylaxis mouse models (ASA). Oral administration of ASP dose-dependently suppressed immunoglobulin (Ig)E-mediated PCA responses evidenced by Evans blue extravasation, ear thickening, and mast cell degranulation. ASP also significantly mitigated ovalbumin-induced ASA responses, including hypothermia, histamine secretion, and the production of IgE and interleukin-4. Notably, ASP was more effective in suppressing allergic inflammation than nothofagin, another prominent flavonoid known as an anti-allergic component of rooibos. The regulatory mechanism of mast cell activation by ASP was clarified using mast cell line and primary cultured mast cells (RBL-2H3 and mouse bone marrow-derived mast cells). ASP reduced IgE-stimulated mast cells degranulation and intracellular calcium influx by the inhibition of Fc epsilon RI signaling pathway (Lyn, Fyn, and Syk). Moreover, ASP reduced pro-inflammatory cytokine expressions by inhibiting two major transcription factors, nuclear factor of activated T cells and nuclear factor-kappa B. Collectively, we proposed that ASP could be a potential therapeutic candidate for the treatment of mast cell-mediated allergic inflammatory diseases. | Kim, Yeyoung; Lee, Soyoung; Jin, Meiling; Choi, Young-Ae; Choi, Jin Kyeong; Kwon, Taeg Kyu; Khang, Dongwoo; Kim, Sang-Hyun | Kyungpook Natl Univ, Sch Med, Dept Pharmacol, CMRI, Taegu 700422, South Korea; Korea Res Inst Biosci & Biotechnol, Immunoregulatory Mat Res Ctr, Jeongeup 56212, South Korea; Yanbian Natl Univ, Sch Med, Dept Pharmacol, Yanji 133001, Peoples R China; Jeonbuk Natl Univ, Med Sch, Dept Immunol, Jeonju 54907, South Korea; Keimyung Univ, Dept Obstet & Gynecol, Sch Med, Daegu 42601, South Korea; Gachon Univ, Sch Med, Dept Physiol, Incheon 21999, South Korea | 58920056700; 8537269200; 59808148000; 7404777420; 50261279600; 7202206057; 26039177500; 57210450420 | dkhang@gachon.ac.kr; shkim72@knu.ac.kr; | INFLAMMATION | INFLAMMATION | 0360-3997 | 1573-2576 | 48 | 1 | SCIE | CELL BIOLOGY;IMMUNOLOGY | 2024 | 5 | 22.7 | 4.41 | 2025-05-07 | 1 | 2 | Allergic inflammation; Mast cells; Aspalathin; Histamine | CA2+ MOBILIZATION; IN-VITRO; LINEARIS; DEGRANULATION; NOTHOFAGIN; ANAPHYLAXIS; ACTIVATION | Allergic inflammation; Aspalathin; Histamine; Mast cells | Anaphylaxis; Animals; Anti-Allergic Agents; Aspalathus; Cell Degranulation; Chalcones; Flavonoids; Hypersensitivity; Immunoglobulin E; Inflammation; Mast Cells; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Receptors, IgE; Signal Transduction; aspalathin; Evans blue; flavonoid; histamine; immunoglobulin E; interleukin 4; ovalbumin; transcription factor; transcription factor NFAT; unclassified drug; antiallergic agent; aspalathin; chalcone derivative; flavonoid; immunoglobulin E; immunoglobulin E receptor; allergic inflammation; animal cell; animal experiment; animal model; Article; bone marrow derived mast cell; calcium cell level; calcium transport; cell activation; cell viability; controlled study; degranulation; degranulation assay; enzyme linked immunosorbent assay; hypothermia; in vivo study; inflammation; male; mast cell; mast cell degranulation; mouse; nonhuman; passive skin anaphylaxis; RBL-2H3 cell line; real time polymerase chain reaction; signal transduction; systemic anaphylaxis; Western blotting; anaphylaxis; animal; Aspalathus; Bagg albino mouse; chemistry; drug effect; drug therapy; hypersensitivity; immunology; metabolism | English | 2025 | 2025-02 | 10.1007/s10753-024-02034-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Depth-Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain | Understanding neural activity across multiple brain regions, especially in three dimensions, is essential for advancing neuroscience research. However, traditional 3D electrode arrays are often restricted to fixed depths, limiting their ability to probe complex brain structures. In this study, a depth-customizable, flexible 3D multi-shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re-fabrication. In vivo experiments produce successful recordings from the motor cortex, somatosensory cortex, and deep structures such as the substantia nigra. Functional connectivity analysis also reveals strong correlations between the substantia nigra and motor cortex, confirming that the developed array can be used to accurately assess neural network dynamics in 3D space. Due to its greater experimental flexibility, the depth-customizable 3D electrode array developed in this study represents a versatile and cost-effective tool for assessing functional connectivity across the entire brain. © 2025 The Author(s). Advanced Electronic Materials published by Wiley-VCH GmbH. | Kim, Minseok; Park, Sehwan; Lee, Haeyun; Lee, Jimin; Chou, Namsun; Shin, Hyogeun | School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, 41566, South Korea; School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, 41566, South Korea; School of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu, 41566, South Korea; Emotion, Cognition & Behavior Research Group, Korea Brain Research Institute (KBRI), Daegu, 41062, South Korea; Emotion, Cognition & Behavior Research Group, Korea Brain Research Institute (KBRI), Daegu, 41062, South Korea; School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, 41566, South Korea, School of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu, 41566, South Korea | 59073001500; 59664022100; 59663830000; 59663877100; 43061070600; 56591066700 | hyogeunshin@knu.ac.kr; nschou@kbri.re.kr; | Advanced Electronic Materials | ADV ELECTRON MATER | 2199-160X | 2199-160X | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2024 | 5.3 | 22.7 | 0 | 2025-05-07 | 0 | 3D electrode arrays; depth-customizable neural probes; functional connectivity; neural signal recording | English | Article in press | 2025 | 10.1002/aelm.202500121 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Independent Association Between Frailty and Fear of Falling in Older Adults After Hip Fracture Surgery: A Cross-Sectional Study Using a Secondary Analysis | Purpose: This study aimed to investigate the independent association between the fear of falling (FOF) and frailty in Korean older adults after hip fracture surgery.Methods: The study included 149 participants. Participants were asked to provide general characteristics and complete walking speed, grip strength, frailty, and Short Falls Efficacy Scale-International assessments. A binary logistic regression model was used to investigate the independent association of the FOF with frailty.Results: Among the participants, 49% were found to be prefrail and 24.8% were frail. Additionally, 86.5% reported a moderate to severe FOF. Participants with a FOF were 1.23 times more likely to be frail, and those aged 85 years and older were 13.25 times more likely to be frail.Conclusion: This study's findings serve as a basis for developing and applying interventions to reduce frailty in older adults after hip fracture surgery. These interventions should consider the oldest-old (>= 85 years) age group when they are designed. | Ko, Youngji; Park, Jungah; Baek, Seung-Hoon | Daegu Haany Univ, Dept Nursing, Gyongsan, Gyeongsangbuk D, South Korea; CHA Univ, Dept Nursing, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Dept Orthoped Surg, Daegu, South Korea | Ko, YoungJi/ABD-6413-2020 | 57209233650; 57402185500; 56232924900 | yjko@dhu.ac.kr; | NURSING RESEARCH AND PRACTICE | NURS RES PRACT | 2090-1429 | 2090-1437 | 2025 | 1 | ESCI | NURSING | 2024 | 2.3 | 22.7 | 0 | 2025-05-07 | 0 | 0 | fear; frail elderly; frailty; hip fractures | SCALE; OUTCOMES; QUALITY | fear; frail elderly; frailty; hip fractures | English | 2025 | 2025 | 10.1155/nrp/2175740 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Navigating Disparities: An In-depth Analysis of Perceived Competency Importance and Training Discrepancies in Clinical Placements Among Students and Clinical Nurses | Purpose: This study investigated the perceived importance and training of competencies during nursing clinical placements by examining the perspectives of nursing students and clinical nurses. Methods: We conducted a cross-sectional study using an online survey of 351 nursing students and 247 clinical nurses. We utilized the Borich needs assessment model to identify the perceived importance and training of competencies during clinical placement. Students and nurses rated their perceived importance and training levels on 32 competency items regarding direct nursing care, indirect nursing care, decision-making and problem-solving, attitude, and nursing professionalism. Results: Students and clinical nurses identified nursing handovers, nursing records, crisis coping abilities, clinical problem identification, clinical decision-making, and priority setting in nursing as competencies of greater importance and with more significant discrepancies from training during clinical placements (Quadrant I in the locus for focus model). Clinical nurses reported examination, skin integrity management, and communication with medical staff as having higher importance and greater discrepancies from training (Quadrant I). In contrast, students recognized them as having lower importance and higher discrepancies (Quadrant II). For students, the perceived importance of all competence domains was significantly associated with the corresponding training (Spearman's rho 1/4 .30-.56, p < .01). For clinical nurses, only the perceived importance of nursing professionalism was associated with all training domains (Spearman's rho z .14.20, p < .05). Conclusion: The disparities between students' and nurses' perceptions of the importance and training of competencies during clinical placements highlight the need to modify the clinical nursing education system. (c) 2025 Korean Society of Nursing Science. Published by Elsevier BV. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | Kim, Su Hyun; Kim, Dayeong; Lee, Sunyoung; Lee, Sojeong; Lee, Hyunjee; Jeon, Hyewon; Kim, Geun-Hee | Kyungpook Natl Univ, Coll Nursing, Inst Nursing Sci, Daegu, South Korea; Kyungpook Natl Univ Hosp, Daegu, South Korea | 56664542600; 57734439700; 59720720100; 59721245600; 59721604700; 59721069200; 58731281800 | suhyun_kim@knu.ac.kr; | ASIAN NURSING RESEARCH | ASIAN NURS RES | 1976-1317 | 2093-7482 | 19 | 2 | SCIE;SSCI | NURSING | 2024 | 2.3 | 22.7 | 0 | 2025-05-07 | 0 | 0 | clinical competence; education; needs assessment; nursing; preceptorship | NURSING-STUDENTS; NEEDS-ASSESSMENT; MODEL | clinical competence; education; needs assessment; nursing; preceptorship | Adult; Attitude of Health Personnel; Clinical Competence; Cross-Sectional Studies; Education, Nursing, Baccalaureate; Female; Humans; Male; Students, Nursing; Surveys and Questionnaires; Young Adult; adult; Article; attitude; clinical competence; clinical decision making; clinical handover; clinical significance; coping; correlation coefficient; cross-sectional study; decision making; education; female; health disparity; human; interpersonal communication; male; medical record; medical staff; needs assessment; nurse; nursing care; nursing education; nursing student; perception; preceptorship; problem identification; problem solving; professionalism; skin; health personnel attitude; nursing education; psychology; questionnaire; young adult | English | 2025 | 2025-05 | 10.1016/j.anr.2025.01.003 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Viable Approach of Tuning Oxide Semiconductor Thin Films in Solution-Processed Heterojunction Thin Films Transistors for Both Higher Performances and Stability | Metal-oxide thin-film transistors (TFTs) have garnered much attention because of their advantages such as high transparency, low leakage current, and low processing temperature. However, there is a need to continuously improve their mobility and bias stability for application to next-generation advanced electronics. In this study, the thickness of bilayer semiconductors is finely controlled to enhance the charge transport characteristics and bias stability in solution-processed heterojunction oxide TFTs. The thicknesses of the top and bottom layers in the bilayer are individually adjusted by controlling solution molarity. The introduction of a bilayer channel improved the electrical performance of oxide TFTs via effective charge transport. However, trap-limited conduction becomes dominant in the bilayer with an excessively thick top layer, thereby leading to a significant reduction in mobility and positive bias stability. Meanwhile, although increasing the bottom layer thickness contributes to improved mobility and reliability, it causes a serious negative shift in threshold voltage (VTH). TFTs with an optimized bilayer structure show high mobility at a VTH close to 0 V and have particularly excellent positive bias stress stability. This study on bilayer channel thickness will be beneficial for developing advanced transistors with optimized bilayer or multilayer channels. Bilayer-channel oxide TFTs are fabricated. The top and bottom active layer characteristics are designed by controlling the semiconductor thickness. Top active layer characteristics affect electron transport and stability in bilayer-channel TFTs. An optimized heterostructure channel leads to effective electron transport and outstanding bias stability. image | Eun, Jun-Su; Lee, Jinuk; Na, Jeong-Hyeon; Park, Jun-Hyeong; Park, Won; Feng, Junhao; Seo, Kyung-Ho; Jang, Jaewon; Kang, In Man; Kim, Do-Kyung; Bae, Jin-Hyuk | Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehak Ro, Daegu 702701, South Korea; LG Display, Paju 10845, South Korea | 58493099200; 58487758300; 57192006339; 57454302100; 58494046100; 57905127500; 59299567400; 57194107504; 7203062678; 57984042900; 35326180700 | kdk7362@knu.ac.kr; jhbae@ee.knu.ac.kr; | ADVANCED ELECTRONIC MATERIALS | ADV ELECTRON MATER | 2199-160X | 11 | 2 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2024 | 5.3 | 22.7 | 2.3 | 2025-05-07 | 2 | 1 | bilayer structure; charge transport characteristics; oxide semiconductors; positive bias stability; semiconductor thickness control; thin-film transistors | ACTIVE-LAYER | bilayer structure; charge transport characteristics; oxide semiconductors; positive bias stability; semiconductor thickness control; thin-film transistors | Carrier concentration; Carrier mobility; Carrier transport; Dry cleaning; Electrospinning; Gluing; Hard facing; Heterojunction bipolar transistors; Indium phosphide; Layered semiconductors; Leakage currents; Oxide films; Thick film circuits; Thin film circuits; Bi-layer; Bi-layer structure; Bias stability; C. thin film transistor (TFT); Charge transport characteristic; Positive bias; Positive bias stability; Semiconductor thickness; Semiconductor thickness control; Transport characteristics; Heterojunctions | English | 2025 | 2025-02 | 10.1002/aelm.202400328 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | High color purity plasmonic color filters integrating Fabry Perot interferometer with distributed Bragg reflector | We present a novel nano structure which combines a Fabry-perot interferometer (FPI) with a plasmonic color filter (PCF) to enhances color purity without increasing fabrication complexity. In the suggested structure, the additional optical resonance operates independently of plasmonic resonance. An FPI was selected for its strong resonance with minimal layers, effectively addressing the wavelength-dependent cavity thickness problem. By optimizing higher-order resonance modes within the FPI, we achieved one cavity of structure with selective transmission peaks at red, green , blue wavelengths, significantly increasing the color gamut by 118.35 % improvement. While the metal-based FPI with PCF (MPCF) exhibited limited peak transmittance due to ohmic loss, the optimized dielectric based FPI with PCF (DPCF) achieved higher transmittance up to 46.81 % , superior color selectivity with a narrow FWHM of 16 nm in blue filter. This led to a 120.29 % enhancement in color purity. Our findings highlight the potential of DPCFs in high-resolution imaging devices, offering a robust alternative to conventional color filters. Future work will focus on optimizing fabrication and exploring materials for further enhancement. | Cho, Hyo Jong; Do, Yun Seon | Kyungpook Natl Univ, Dept Elect & Elect Engn, Daegu 41566, South Korea | 57216649076; 24338060500 | yuns.do@knu.ac.kr; | OPTICAL MATERIALS | OPT MATER | 0925-3467 | 1873-1252 | 162 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;OPTICS | 2024 | 4.2 | 22.8 | 0 | 2025-05-07 | 0 | 0 | OPTICAL-TRANSMISSION; LIGHT; FABRICATION | Bandpass filters; Distributed Bragg reflectors; Fiber optic sensors; Laser beams; Cavity thickness; Color filters; Color purity; Distributed-bragg-reflectors; Fabry-Perot; Nano-structures; Optical resonance; Plasmonic resonances; Plasmonics; Strong resonance; Fabry-Perot interferometers | English | 2025 | 2025-05 | 10.1016/j.optmat.2025.116831 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Synthesis of fluorescent dyes for polyolefin fibers and their fluorescence emission properties | Two novel greenish-yellow fluorescent dyes sharing the same chromophore were synthesized. Dibutyl groups were introduced into the chromophore to enhance their affinity for extremely hydrophobic polyolefin materials, such as polypropylene and ultra-high molecular weight polyethylene (UHMWPE). Despite the similarity in their chromophores, the dye-containing sulfur atoms exhibited significantly superior fluorescence emission properties compared to the dye-containing oxygen atoms, likely due to the heavy atom effect. Comparative experiments involving different dyes, fabrics, and dyeing conditions demonstrated that polyolefin fabrics, previously undyeable with commercial dyes, were successfully dyed with the synthesized fluorescent dyes, maintaining excellent fluorescence properties after application. Additionally, the dyed fabrics exhibited excellent washability and color fastness, except for light fastness. | Lee, Junheon; Jeon, Kanghoon; Lee, Seongho; Kim, Taekyeong | Kyungpook Natl Univ, Coll Engn, Dept Text Syst Engn, Daegu, South Korea | 57195904688; 58964396600; 59368607200; 24587275700 | taekyeong@knu.ac.kr; | OPTICAL MATERIALS | OPT MATER | 0925-3467 | 1873-1252 | 159 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;OPTICS | 2024 | 4.2 | 22.8 | 0 | 2025-05-07 | 0 | 0 | Fluorescence; Dye; Fiber; Polyolefin; Hydrophobicity; Heavy atom effect | DIFFERENCE; MECHANISM; TEXTILE; COLOR | Dye; Fiber; Fluorescence; Heavy atom effect; Hydrophobicity; Polyolefin | Dyeing; Vat dyes; Emission properties; Fluorescence emission; Fluorescent dyes; Heavy atom effects; High molecular weight polyethylenes; Hydrophobics; Polyolefin fibers; Sulphur atoms; Synthesised; Ultra-high-molecular-weight; Ultrahigh molecular weight polyethylenes | English | 2025 | 2025-02 | 10.1016/j.optmat.2025.116670 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Amelioration of Alcoholic Hepatic Steatosis in a Rat Model via Consumption of Poly-γ-Glutamic Acid-Enriched Fermented Protaetia brevitarsis Larvae Using Bacillus subtilis | Alcoholic hepatic steatosis (AHS) is a common early-stage symptom of liver disease caused by alcohol consumption. Accordingly, several aspects of AHS have been studied as potential preventive and therapeutic targets. In this study, a novel strategy was employed to inhibit fatty liver accumulation and counteract AHS through the consumption of microorganism-fermented Protaetia brevitarsis larvae (FPBs). By using an AHS rat model, we assessed the efficacy of FPB by examining the lipid profile of liver/serum and liver function tests to evaluate lipid metabolism modulation. After FPB administration, the lipid profile-including high-density lipoprotein, total cholesterol, and total triglycerides-and histopathological characteristics exhibited improvement in the animal model. Interestingly, AHS amelioration via FPBs administration was potentially associated with poly-gamma-glutamic acid (P gamma G), which is produced by Bacillus species during fermentation. These findings support the formulation of novel natural remedies for AHS through non-clinical animal studies, suggesting that P gamma G-enriched FPBs are a potentially valuable ingredient for functional foods, providing an ameliorative effect on AHS. | Sim, So-Yeon; Cho, Hyun-Dong; Lee, Sae-Byuk | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, 80 Daehak Ro, Daegu 41566, South Korea; Sunchon Natl Univ, Dept Food & Nutr, Sunchon 57922, South Korea; Kyungpook Natl Univ, Inst Fermentat Biotechnol, 80 Daehak Ro, Daegu 41566, South Korea | 57208102487; 55383853000; 57188742752 | salley4565@knu.ac.kr; hdcho@scnu.ac.kr; lsbyuck@knu.ac.kr; | FOODS | FOODS | 2304-8158 | 14 | 5 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2024 | 5.1 | 22.9 | 0 | 2025-05-07 | 0 | 0 | alcoholic hepatic steatosis; Bacillus subtilis; fermentation; lipid metabolism modulation; poly-gamma-glutamic acid; Protaetia brevitarsis larvae | HIGH-FAT DIET; OXIDATIVE STRESS; LIVER-INJURY; DEHYDROGENASE; ALBUMIN | alcoholic hepatic steatosis; Bacillus subtilis; fermentation; lipid metabolism modulation; poly-γ-glutamic acid; Protaetia brevitarsis larvae | English | 2025 | 2025-03 | 10.3390/foods14050861 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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