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Article Effects of loading rate on the strength and failure of cemented sand This study investigates the effects of cement content (CC) and loading rate on the unconfined compressive strength (UCS) of cemented sand. Three CCs (12%, 14%, and 16%) were tested at loading rates ranging from 0.5%-5%/min. In addition, a novel camera vision-based crack detection method was developed to monitor crack-related parameters-crack size and angle-in real-time during testing. The results revealed significant variations in UCS with changes in CC and loading rate. For example, at a loading rate of 0.5%/min, UCS increased by 31% and 102% in the specimens with 12% and 16% CC, respectively. Moreover, UCS consistently increased with increasing loading rate, with increases of 28%, 36%, and 31% observed for CCs of 12%, 14%, and 16%, respectively, within the 0.5%-1%/min range. However, as the loading rate increased above 1%/min, the rate of UCS increase stabilized or decreased, highlighting the importance of selecting appropriate loading rates for accurate strength evaluation. A correlation between normalized UCS and loading rate is proposed based on this study's findings and previous research. Furthermore, the camera-based crack detection method provides detailed insights into the failure behavior of cemented sand and reveals a clear correlation between loading rate, CC, and the angle of the fracture surface. This study highlights the need to adopt a standardized loading rate of 1%/min in UCS testing of cemented sand and demonstrates the potential of camera vision technology to enhance geotechnical monitoring practices. Woo, Seung-Wook; Lee, Dong-Eun; Nguyen, Nhut-Nhut; Hwang, Keum-Bee; Park, Sung-Sik; Tran, Dong-Kiem-Lam Kyungpook Natl Univ, Dept Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Architectural Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Intelligent Construct Automat Ctr, 80 Daehak Ro, Daegu 41566, South Korea; Univ Architecture Ho Chi Minh City, Dept Civil Engn, 196 Pasteur Vo Thi Sau Ward,Dist 3, Ho Chi Minh City 72400, Vietnam Tran, Dong-Kiem-Lam/KLY-3827-2024 57212917862; 56605563300; 57211211964; 57347017900; 36241850300; 57217738208 geowsw@knu.ac.kr; dolee@knu.ac.kr; nguyennhutnhut@hcmut.edu.vn; adela_0224@naver.com; sungpark@knu.ac.kra; lam.trandongkiem@uah.edu.vn; COMPUTERS AND CONCRETE COMPUT CONCRETE 1598-8198 1598-818X 35 3 SCIE COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, CIVIL;MATERIALS SCIENCE, CHARACTERIZATION & TESTING 2024 3.3 20.3 0 2025-05-07 1 1 camera vision-based crack detection; cemented content; fracture surface angle; loading rate; unconfined compressive strength UNCONFINED COMPRESSIVE STRENGTH; FIBER-REINFORCEMENT; CRACK DETECTION; BEHAVIOR; COAL camera vision-based crack detection; cemented content; fracture surface angle; loading rate; unconfined compressive strength Cements; Crack detection; Fracture mechanics; Camera vision; Camera vision-based crack detection; Cement content; Cemented content; Cemented sands; Fracture surface angle; Fracture surfaces; Loading rate; Unconfined compressive strength; Vision based; Compressive strength English 2025 2025-03 10.12989/cac.2025.35.3.281 바로가기 바로가기 바로가기 바로가기
Article Gene Expression Depends on the Interplay Among Growth, Resource Biogenesis, and Nutrient Quality The gene expression capacity of bacteria depends on the interplay between growth and the availability of the transcriptional and translational machinery. Growth rate is accepted as the physiological parameter controlling the allocation of cellular resources. Understanding the relationship between growth and resources is key for the efficient design of genetic constructs, but it is obscured by the mutual dependence between growth and gene expression. In this work, we investigate the contributions of molecular factors, growth rate, and metabolism to gene expression by investigating the behavior of bacterial cells grown in chemostats. Using a model of the whole cell and validating it experimentally, our results show that while growth rate and molecular factors, such as the number of rRNA operons, set the abundance of transcriptional and translational machinery, it is metabolism that governs the usage of resources by tuning elongation rates. We show, using a biotechnologically relevant example, that gene expression capacity can be maximized using low growth in a high-quality medium. These findings unveil fundamental trade-offs in physiology that will inform future bioprocess optimization. Kim, Juhyun; Darlington, Alexander P. S.; Munoz-Montero, Said; Montenegro, Rafael; Dalby, Perrine; Herrera-Martin, Noemi; Banks, Alice; Prakash, Satya; Polizzi, Karen; Bates, Declan G.; Jimenez, Jose I. Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea; Univ Warwick, Sch Engn, Coventry CV4 7AL, England; Imperial Coll London, Dept Life Sci, South Kensington Campus, London SW7 2AZ, England; Imperial Coll London, Dept Chem Engn, South Kensington Campus, London SW7 2AZ, England 55829164000; 57192921030; 57217976286; 57222347226; 59921498600; 59921880700; 57192872558; 58505381900; 10039266100; 7202955672; 15922896500 a.darlington1@warwick.ac.uk; j.jimenez@imperial.ac.uk; ACS SYNTHETIC BIOLOGY ACS SYNTH BIOL 2161-5063 14 6 SCIE BIOCHEMICAL RESEARCH METHODS 2024 3.9 20.3 0 2025-06-11 0 0 ribosomes; cellular economics; metabolic constraints; (p)ppGpp; resource allocation; metabolic burden ESCHERICHIA-COLI; COPY-NUMBER; TRADE-OFFS; PPGPP; PROTEIN; STARVATION; PROMOTERS; CAPACITY; NETWORK; BINDING (p)ppGpp; cellular economics; metabolic burden; metabolic constraints; resource allocation; ribosomes proteome; Article; bacterial cell; bacterial growth; biogenesis; carbon source; controlled study; gene expression; genetic linkage; growth rate; metabolism; nonhuman; nutrient; operon; resource allocation; ribosome; RNA transcription; RNA translation; validation process; whole cell English 2025 2025-05-29 10.1021/acssynbio.4c00828 바로가기 바로가기 바로가기 바로가기
Article High-fat diet promotes lipotoxicity in the podocytes of uninephrectomized mice: a targeted lipidomics and kidney podocyte-specific analysis Abnormal lipid metabolism is an independent risk factor for kidney injury, significantly altering the associated gene expression, particularly in single kidney models. This study investigates the impact of high-fat diet-induced lipid metabolism on podocyte injury in uninephrectomized mice. Using targeted lipidomics analysis and podocyte-specific assays, the modification of lipid profiles attributed to a high-fat diet and the development of podocyte injury caused by lipid metabolism in mice that underwent unilateral nephrectomy were examined. Mice that underwent unilateral nephrectomy and were fed with a high-fat diet for 13 weeks exhibited progressive renal dysfunction, including the accumulation of lipid droplets in podocytes, vacuolization of tubular cells, and glomerular hypertrophy. Liquid chromatography-triple quadrupole mass spectrometry confirmed a significant increase in cholesteryl ester 20:4 levels in the podocytes of these mice. In vitro, cholesteryl ester 20:4 treatment reduced mitochondrial respiration capacity and mitochondrial glycolysis in podocytes. Furthermore, the treatment led to alterations in the protein expression levels associated with lipid metabolism and transport, mitochondrial activity, and autophagy, including ATP binding cassette subfamily A member 1 (ABCA1), carnitine palmitoyltransferase 1 A (CPT1A), acyl-CoA cholesterol acyltransferase (ACAT), nuclear respiratory factor 1/2 (NRF 1/2), dynamin-1-like protein (DRP1), and p62. Transcriptome sequencing analysis revealed impaired gene expression, which was associated with the progression of renal fibrosis in unilateral nephrectomy mice with a high-fat diet. Specifically, the expression of matrix metalloproteinases and collagen genes, including fibronectin and collagen IV, was upregulated, indicating fibrosis progression. In conclusion, lipidomics analysis identifies cholesteryl ester 20:4 as a key lipid metabolite accumulating in podocytes, which is associated with mitochondrial dysfunction and abnormal autophagy. This accumulation potentially contributes to structural and functional deterioration in the kidney and highlights its role in kidney damage and its potential as a therapeutic target in metabolic kidney diseases. Oh, Se-Hyun; Kim, You-Jin; Bae, Subin; Jung, Hee-Yeon; Park, So-Young; Lim, Jeong-Hoon; Cho, Jang-Hee; Kim, Chan-Duck; Park, Sun-Hee; Kwon, Tae-Hwan; Kim, Yong-Jin; Liu, Kwang-Hyeon; Kim, Yong-Lim Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Daegu, South Korea; Kyungpook Natl Univ, BK21 FOUR Community Based Intelligent Novel Drug D, Daegu, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu, South Korea; Kyungpook Natl Univ, Mass Spectrometry Based Convergence Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biochem & Cell Biol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pathol, Daegu, South Korea Jung, Hee-Yeon/AFB-8578-2022; Lim, Jeong-Hoon/ABE-6003-2020; Cho, Jang-hee/ABD-3534-2020 56053033900; 57190286137; 57224532908; 57196396467; 57211630074; 55360244300; 7403536291; 59216189400; 7501831741; 7202206089; 56150365500; 55768214700; 55633533600 dstlkh@knu.ac.kr; ylkim@knu.ac.kr; CELL DEATH DISCOVERY CELL DEATH DISCOV 2058-7716 11 1 SCIE CELL BIOLOGY 2024 7 20.3 0 2025-05-07 0 0 MITOCHONDRIAL DYNAMICS; OBESITY; DISEASE; BODY; RISK English 2025 2025-04-23 10.1038/s41420-025-02419-7 바로가기 바로가기 바로가기 바로가기
Article Investigation of the Peculiar Stress Flow Behavior of a Novel TiAl Alloy under High Strain Rate Conditions In this study, we investigated the peculiar flow behavior during the isothermal deformation of a novel TiAl composition at 1200 degrees C and 1300 degrees C under high strain rate conditions using Gleeble (R) Thermal-Mechanical Simulators. The initial yield-point phenomenon, resembling strain hardening at both temperatures, is attributed to the remnant lamellar microstructure. Secondary hardening at 1200 degrees C is caused by dislocation accumulation at the grain boundaries of the alpha phase, without the formation of dynamically recrystallized gamma lamellar grains. In-grain misorientation axes analysis revealed a shift in the dominant deformation slip mode of the alpha phase from the prismatic slip system to a combined prismatic and basal slip system. The disappearance of gamma lamellar laths after the first strain hardening and during secondary hardening is likely initiated by a deformation-induced gamma ->alpha phase transition within the gamma phase matrix by the extended dislocation with intrinsic stacking faults and occurred simultaneously in the whole gamma lamellae. Park, Ji-Sung; Kim, Min-Sik; Won, Jong-Woo; Kim, Seong-Woong; Yi, Seong-Hoon Korea Inst Mat Sci, Extreme Mat Res Inst, Chang Won 51508, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea Kim, Min-Sik/KFS-9148-2024 57879257100; 58184805400; 54407777500; 7601591610; 59540400900 mrbass@kims.re.kr; yish@knu.ac.kr; METALS AND MATERIALS INTERNATIONAL MET MATER INT 1598-9623 2005-4149 31 7 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING 2024 4 20.3 0 2025-05-07 0 0 Yield point phenomenon; Isothermal compression; Strain hardening; Deformation-induced phase transition; IGMA DYNAMIC RECRYSTALLIZATION; MECHANICAL-PROPERTIES; PHASE-TRANSFORMATION; DEFORMATION-BEHAVIOR; HOT DEFORMATION; HIGH-NB; MICROSTRUCTURAL EVOLUTION; THERMAL-STABILITY; GAMMA; LAMELLAR Deformation-induced phase transition; IGMA; Isothermal compression; Strain hardening; Yield point phenomenon Age hardening; Dislocations (crystals); Dynamic recrystallization; Grain boundaries; Isotherms; Lamellar structures; Stacking faults; Strain hardening; Strain rate; Titanium alloys; Condition; Deformation-induced phase transition; Flow behaviours; High-strain-rate; IGMA; Induced phase transition; Isothermal compressions; Secondary Hardening; Yield point phenomenon; Yield points English 2025 2025-07 10.1007/s12540-024-01859-7 바로가기 바로가기 바로가기 바로가기
Article Liquid crystal aptamer-based sensor with a functionalized amphiphilic block copolymer for the detection of m-hydroxy cocaine Cocaine detection is crucial for public health and safety, as it plays a vital role in curbing substance abuse, reducing crime, and protecting individuals from its harmful effects. This research utilizes 4-cyano-4'-pentylbiphenyl (5CB) confined in a transmission electron microscopy (TEM) grid and functionalized with a poly(styreneb-acrylic acid) (PS-b-PAA) monolayer (5CBPAA). The PS anchors the block-co-polymer in the 5CB, and a cocaine-specific aptamer (CA) is covalently immobilized onto the PAA (5CBPAA-aptamer) to detect m-hydroxy cocaine in solution and human urine samples. An initial homeotropic alignment of the 5CB is achieved by optimizing the CA concentration, and monitoring m-hydroxy cocaine is enabled via a homeotropic-to-planar orientation change of the 5CB. The 5CBPAA-aptamer system detects cocaine within the range of 5-50 nM, with a limit of detection of 5 nM. Additionally, successful cocaine detection has been performed in human urine samples by introducing cocaine into the urine after collection. The study also encompasses the evaluation of the 5CBPAA-aptamer grid's stability for up to 20 days and the conduction of selectivity tests in the presence of other interfering substances. This study establishes the 5CBPAA-aptamer system as a simple, cost-effective, selective, and sensitive platform for detecting cocaine, with potential applications in resource-limited settings. Khan, Bilal ud din; Khan, Mashooq; Hu, Qiongzheng; Park, Soo-Young Kyungpook Natl Univ, Dept Polymer Sci & Engn, Polymer Nanomat Lab, 1370 Sangyuk Dong, Daegu 41566, South Korea; Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Jinan 250014, Peoples R China Hu, Qiongzheng/P-4187-2015 59146081900; 57194050547; 46461298600; 57194041850 psy@knu.ac.kr; MICROCHEMICAL JOURNAL MICROCHEM J 0026-265X 1095-9149 213 SCIE CHEMISTRY, ANALYTICAL 2024 5.1 20.3 0 2025-05-07 0 0 Liquid crystal; Aptamer; Aptasensor; Cocaine; Block copolymer; Poly (styrene)-b-poly (acrylic acid) METABOLITES; SELECTION; BINDING Aptamer; Aptasensor; Block copolymer; Cocaine; Liquid crystal; Poly (styrene)-b-poly (acrylic acid) English 2025 2025-06 10.1016/j.microc.2025.113595 바로가기 바로가기 바로가기 바로가기
Article An Ontological Perspective on Mechanical Energy Conservation problem-solving in high School Students This study explores the ontological perspective in analyzing students' problem-solving related to mechanical energy conservation. The research involves 18 high school students whose explanations were qualitatively analyzed using an extended ontological framework. Initially, students predominantly employed matter-based predicates and formula-centered representations in the first-step problem-solving. However, in the second step, there was a transition towards process-based predicative expressions and representations, such as reformulating, proportional expressions, symbols, and tables, alongside continued use of matter-based expressions. This phase reflects the students' conceptual shift toward including the "process" category in their understanding of energy concepts. In the third step, most students demonstrated process-based predicative expressions and representations, emphasizing concepts like "conversion" and "transfer." This transition indicates a shift from the ontological category of "matter" to "process," evident in both predicates and representation formats. The findings suggest that understanding students' concepts through an ontological lens not only enhances teaching and learning physics but also contributes to the integration of ontological concepts into science education. Kim, Hyojoon; Ha, Sangwoo Korea Inst Curriculum & Evaluat, Jincheongun 27873, Chungcheongbukd, South Korea; Kyungpook Natl Univ, Dept Phys Educ, 80 Daehakro Bukgu, Daegu 41566, South Korea Ha, Sangwoo/HPB-9765-2023 57211120002; 55215468100 hswgcb@knu.ac.kr; RESEARCH IN SCIENCE EDUCATION RES SCI EDUC 0157-244X 1573-1898 55 3 SSCI EDUCATION & EDUCATIONAL RESEARCH 2024 2.3 20.4 0 2025-05-07 0 0 Mechanical Energy Conservation; Problem Solving; Ontological Category LEARNING PROGRESSION; PHYSICS; SCIENCE Mechanical Energy Conservation; Ontological Category; Problem Solving English 2025 2025-06 10.1007/s11165-024-10199-w 바로가기 바로가기 바로가기 바로가기
Article Resource Allocation in Quantum-Key-Distribution Optical Data Center Networks The paper investigates quantum key resource allocation in quantum-key-distribution optical data center networks (QKD-ODCNs). A novel framework of priority queue with multiple security levels is first proposed to achieve a multi-class networking environment with adaptive security level classification. Accordingly, a novel integer linear programming (ILP) model is developed for the quantum key resource allocation (QKRA) process. To overcome the high computation complexity in solving the ILP, two heuristic approaches are developed, namely QKRA with adaptive strong security level (QKRA-ASSL) and QKRA with adaptive weak security level (QKRA-AWSL), respectively, aiming to achieve as close performance to that by the ILP model as possible in terms of success rate of connection request and network security level. The simulation results verify that the proposed QKRA-ASSL and QKRA-AWSL approaches not only maximize the network security score, but also improve the timeslot resource utilization without compromising the establishment success rate of connection request. Chen, Bowen; Ma, Weike; He, Bin; Chen, Hong; Jiang, Min; Shao, Weidong; Gao, Mingyi; Peng, Limei; Ho, Pin-Han; Jue, Jason P. Soochow Univ, Sch Elect & Informat Engn, Suzhou 215006, Peoples R China; Kyungpook Natl Univ, Dept Comp Sci, Daegu 41566, South Korea; Univ Waterloo, Dept Elect & Comp Engn, Waterloo, ON N2L 3G1, Canada; Univ Texas Dallas, Erik Jonsson Sch Engn & Comp Sci, Richardson, TX 75080 USA 8578301300; 57222291822; 57211324216; 57866626000; 57191039477; 37121009400; 36666264800; 7201574271; 7402211578; 7006764727 bwchen@suda.edu.cn; JOURNAL OF LIGHTWAVE TECHNOLOGY J LIGHTWAVE TECHNOL 0733-8724 1558-2213 43 11 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;OPTICS;TELECOMMUNICATIONS 2024 4.8 20.4 0 2025-05-07 0 0 Security; Optical fiber networks; Data centers; Resource management; Network security; Optical fibers; Optical polarization; Quantum computing; Quantum channels; Encryption; Optical data center network; quantum key distribution; resource allocation QKD Optical data center network; quantum key distribution; resource allocation Integer linear programming; Integer programming; Mixed-integer linear programming; Network security; Optical data processing; Quantum cryptography; Resource allocation; Data center networks; Integer linear programming models; Key distribution; Key resources; Networks security; Optical data; Optical data center network; Quantum key; Resources allocation; Security level; Data centers English 2025 2025-06-01 10.1109/jlt.2025.3543745 바로가기 바로가기 바로가기 바로가기
Article Adapting and Validating a Moral Identity Scale for Korean Intensive Care Unit Nurses This study aimed to adapt and validate a Korean version of the Moral Identity Scale developed by Aquino and Reed. Intensive care unit (ICU) nurses face several moral conflict or challenging situations where they make difficult decisions related to the rationing of care or prioritization such as a shortage of medical supplies and staffing. To understand the reason behind choosing moral values over other values such as economic and personal ones by nurses during such times, conceptual research on moral identity is required. However, this has not been studied using empirical data analysis despite the increased significance of nurses' moral identity. A secondary data analysis and a methodological design were employed. Data were collected from 207 ICU nurses. Exploratory and confirmatory factor analyses were used to test the construct validity. The results of exploratory factor analysis showed that the Eigenvalues ranged from 1.63 to 4.47 and comprised 52.17% of the total explained variance. Confirmatory factor analysis showed acceptable model fit indices (chi 2 [p] = 28.822 [.051], df = 18, root mean square error of approximation = 0.076, goodness-of-fit index = 0.937, Tucker-Lewis index = 0.93, and comparative fit index = 0.955) and standardized factor loadings (0.45-0.82). As professionals, ICU nurses must protect and advocate for the patient according to their own moral identity. Therefore, the Korean version of the Moral Identity Scale is a valid and reliable instrument that can be used in nursing education programs for improving the moral identity of ICU nurses. Lee, Junghoon; Song, Yeoungsuk Daegu Catholic Univ, Gyongsan, South Korea; Kyungpook Natl Univ, Coll Nursing, 80 Daehak Ro, Daegu 41566, South Korea 57218996809; 55494171100 asansong@knu.ac.kr; SAGE OPEN SAGE OPEN 2158-2440 15 2 SSCI SOCIAL SCIENCES, INTERDISCIPLINARY 2024 2 20.5 0 2025-06-11 0 0 intensive care; intensive care nursing; moral identity; ethics; validity; reliability AUTHENTIC LEADERSHIP; SAMPLE-SIZE; FOLLOWER ethics; intensive care; intensive care nursing; moral identity; reliability; validity English 2025 2025-04 10.1177/21582440251340870 바로가기 바로가기 바로가기 바로가기
Article Deep learning applications on satellite imagery datasets for nuclear nonproliferation and counter-proliferation This study examined the applicability of deep-learning techniques for extracting artificial structures from highresolution satellite imagery to support verification processes in nuclear nonproliferation and counterproliferation efforts. This examination relied on a tailored dataset and an open-source dataset. The tailored dataset was curated using satellite images of well-known nuclear complexes and was further refined to enhance domain relevance. Furthermore, using the attention U-Net model, optimal values of parameters such as batch size were determined to enhance performance. The model was then tested on satellite images of nuclear facilities from various sources, demonstrating effective performance even when applied to distinct and complex environments. To assess the robustness of the model, accuracy evaluations were conducted using both pixel-based and object-based tests. This dual evaluation approach provided a comprehensive analysis of the model, highlighting its practical utility for real-world verification tasks, particularly those related to nuclear activities. Although some false positives were detected, the proposed approach enabled the successful extraction of the majority of structures of interest. This achievement is anticipated to substantially reduce the interpretational workload for analysts and offer a transferable solution for global nuclear monitoring applications. Han, Jae-Jun; Ha, Gayeon; Han, Youkyung; Lee, Changhui; Lee, Hyunjin; Song, Ahram Korea Inst Nucl Nonproliferat & Control, 1418 Yuseong Daero, Daejeon, South Korea; Seoul Natl Univ Sci & Technol, Dept Civil Engn, 232 Gongneung Ro, Seoul, South Korea; Kyungpook Natl Univ, Dept Locat Based Informat Syst, 2559 Gyeongsang Daero, Sangju, South Korea 59731553600; 57209009868; 55457676600; 57339201100; 58084009500; 56496312900 ars@knu.ac.kr; ANNALS OF NUCLEAR ENERGY ANN NUCL ENERGY 0306-4549 1873-2100 219 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2024 2.3 20.7 0 2025-05-07 0 0 Nuclear Nonproliferation; IAEA Safeguards; Additional Protocol; Counter-Proliferation; Satellite Imagery; Building Segmentation; Attention U -Net Additional Protocol; Attention U-Net; Building Segmentation; Counter-Proliferation; IAEA Safeguards; Nuclear Nonproliferation; Satellite Imagery Deep learning; Image enhancement; Image segmentation; Nuclear materials safeguards; Additional Protocol; Artificial structures; Attention U-net; Building segmentation; Counter-proliferation; High resolution satellite imagery; IAEA Safeguards; Learning techniques; Nuclear nonproliferation; Satellite images; Satellite imagery English 2025 2025-09-01 10.1016/j.anucene.2025.111443 바로가기 바로가기 바로가기 바로가기
Article Experimental and numerical analyses for boiling model selection and nonuniform void behavior at the onset of flow instability Numerical analyses were conducted to simulate the flow boiling phenomenon using different boiling models under natural circulation conditions. From the analyzed results, bubble behaviors were investigated at the onset of nucleate boiling (ONB) and the onset of flow instability (OFI). At the ONB, the predictions obtained for the bubble diameter, nucleation site density, and void fraction were compared with the experimental data. At the OFI, the bubble diameter, nucleation site density, void fraction, and bubble movement with respect to time were investigated. Among 4 cases with different combinations of boiling models, Case 1 was selected because the wall temperature, bubble diameter, nucleation site density, and void fraction were well predicted considering the agreement between the experimental and computational fluid dynamics results. When flow instability started as the heat flux increased, bubble behavior was nonuniform although heat flux was uniformly generated on the heated surface. Park, Ji-Hwan; Kim, Byoung Jae; Jo, Daeseong Kyungpook Natl Univ, Grad Sch, Dept Mech Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehak Ro, Daegu 702701, South Korea; Chungnam Natl Univ, Sch Mech Engn, 99 Daehak Ro, Daejeon 34134, South Korea Kim, Seonghwan/AAZ-1679-2021 57219163330; 59270751500; 16424303000 djo@knu.ac.kr; ANNALS OF NUCLEAR ENERGY ANN NUCL ENERGY 0306-4549 1873-2100 210 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2024 2.3 20.7 0 2025-05-07 0 0 Bubble diameter; Natural circulation; Nucleation site density; Onset of flow instability; Onset of nucleate boiling NARROW RECTANGULAR CHANNEL; LOW-PRESSURE; UNIFORM; DIAMETER; WATER Bubble diameter; Natural circulation; Nucleation site density; Onset of flow instability; Onset of nucleate boiling Natural convection; Boiling models; Bubble behavior; Bubble diameter; Experimental and numerical analysis; Flow instabilities; Model Selection; Natural circulation; Nucleation site density; Onset of flow instability; Onset of nucleate boiling; Nucleate boiling English 2025 2025-01 10.1016/j.anucene.2024.110840 바로가기 바로가기 바로가기 바로가기
Article Photon and thermal neutron shielding behaviors of aluminum calcium fluoroborate glass modified with barium oxide: FLUKA Monte Carlo, XCOM and experimental investigations The borate glass system was prepared using the melt-quenching method. The XRD was used to confirm the amorphous structure of present samples, the FTIR was utilized to observe vibration modes, and the UV-Vis-NIR - Vis-NIR spectrophotometer was employed to measure transmittance spectra. The radiation shielding properties were examined by FLUKA Monte Carlo simulation, XCOM programs, and experimental methods. The density increased, while the molar volume decreased as the BaO content increased. For the X-ray and gamma-ray radiation, indicate that the addition of BaO instead of B2O3 2 O 3 improve the shielding properties, while the Sigma is decreased for thermal neutron radiation. According to the results, adding BaO enhanced the X-ray and gamma- ray shielding properties. However, adding BaO led to the reduces its ability of shielding the thermal neutrons of the glass samples. These data are expected to be accommodate to considering for any applications which requires high efficiency of photon or thermal neutrons shielding. Mutuwong, C.; Bootjomchai, C.; Chaiphaksa, W.; Cheewasukhanont, W.; Sommat, V.; Kaewjaeng, S.; Ornketphon, O.; Intachai, N.; Kothan, S.; Kim, H. J.; Kaewkhao, J. Ubon Ratchathani Univ, Fac Sci, Dept Phys, Warin Chamrap 34190, Ubon Ratchathan, Thailand; Nakhon Pathom Rajabhat Univ, Fac Sci & Technol, Phys Program, Nakhon Pathom 73000, Thailand; Nakhon Pathom Rajabhat Univ, Ctr Excellence Glass Technol & Mat Sci CEGM, Nakhon Pathom 73000, Thailand; Chiang Mai Univ, Off Res Adm, Chiang Mai 50200, Thailand; Chiang Mai Univ, Fac Associated Med Sci, Ctr Radiat Res & Med Imaging, Dept Radiol Technol, Chiang Mai 50200, Thailand; Naresuan Univ, Fac Allied Hlth Sci, Dept Radiol Technol, Phitsanulok 65000, Thailand; Kyungpook Natl Univ, Dept Phys, Daegu, South Korea Chaiphaksa, Wuttichai/KGM-7876-2024; Bootjomchai, Cherdsak/E-9438-2015; Intachai, Nuttawadee/HOH-1735-2023; Mutuwong, Chalermpon/AAX-4666-2020 57205297955; 53881131300; 56267524400; 57118163600; 58990705600; 55871868200; 57215209007; 57221909427; 6507017165; 58483690400; 23974520300 cherdsak2303@gmail.com; jakrapong@webmail.npru.ac.th; ANNALS OF NUCLEAR ENERGY ANN NUCL ENERGY 0306-4549 1873-2100 210 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2024 2.3 20.7 15.22 2025-05-07 5 5 FLUKA; Shielding properties; Borate glass; BaO; Monte Carlo BORATE GLASSES; RADIATION; EXPOSURE; ENERGY; LEAD BaO; Borate glass; FLUKA; Monte Carlo; Shielding properties Barium sulfate; Borate minerals; Glass; Heat shielding; Radiation shielding; Barium oxides; Borate glass; Experimental investigations; FLUKA; Fluoroborate glass; Glass systems; Monte carlo; Neutron shielding; Shielding properties; Thermal neutrons; Gamma rays English 2025 2025-01 10.1016/j.anucene.2024.110863 바로가기 바로가기 바로가기 바로가기
Article Precise Internal Postsynthetic Oxygen-Doping of Metallonanographenes Heteroatom doping has the potential to alter the electronic structure and optical properties of nanographenes, thereby expanding the scope of their utility in various applications. In this work we demonstrate a strategy to introduce an oxygen atom directly and precisely into backbone of the already formed metal-nanographene complexes. Treating metal-nanographene complexes HBCP-M (M = Cu, Ag, Au) with Davis’ oxaziridine produces oxygen-doped complexes HBCP-OM (M = Cu, Ag, Au) with adj-CONN coordination in one step. Compared with original metal complexes, the electronic structure, photophysical properties and molecular conformations of HBCP-OM show sharp changes, as indicated by steady and fs-transient absorption (TA) spectroscopies, DFT calculations and crystal structure analysis. Moreover, the reduction of coordination cavity of HBCP-OM due to oxygen insertion affects the metal-ligand interaction. This leads that HBCP-OCu, possessing a relatively small Cu(III) cation, exhibits an extended near-infrared (NIR) absorption beyond 1300 nm that is not observed in HBCP-OAg and HBCP-OAu. © 2025 The Authors. Co-published by University of Science and Technology of China and American Chemical Society. He, Haodan; Lee, Jiyeon; Zong, Zhaohui; Lim, Kyeong Mo; Ryu, Jaehyeok; Oh, Juwon; Kim, Jiwon; Sessler, Jonathan L.; Ke, Xian-Sheng College of Chemistry, Beijing Normal University, Beijing, 100875, China; School of Integrated Technology, College of Computing, Yonsei University, Incheon, 21983, South Korea; College of Chemistry, Beijing Normal University, Beijing, 100875, China; Department of Chemistry, Kyungpook National University, Daegu, 41566, South Korea; School of Integrated Technology, College of Computing, Yonsei University, Incheon, 21983, South Korea; Department of Chemistry, Kyungpook National University, Daegu, 41566, South Korea; School of Integrated Technology, College of Computing, Yonsei University, Incheon, 21983, South Korea, Integrated Science and Engineering Division, Underwood International College, Department of Integrative Biotechnology, Graduate School, Yonsei University, Incheon, 21983, South Korea; Department of Chemistry, The University of Texas at Austin, Austin, 78712-1224, TX, United States; College of Chemistry, Beijing Normal University, Beijing, 100875, China 58085044400; 57210790315; 58796067900; 57805008000; 58627667500; 55812113000; 57191681250; 7102304338; 55522916400 juwoh933@knu.ac.kr; jiwon.kim@yonsei.ac.kr; sessler@cm.utexas.edu; kexiansheng@bnu.edu.cn; Precision Chemistry PRECIS CHEM N/A 2771-9316 ESCI CHEMISTRY, MULTIDISCIPLINARY 2024 6.2 20.7 0 2025-06-11 0 aromaticity; carbaporphyrin; electronic structure; Nanographene; oxygen doping English Article in press 2025 10.1021/prechem.5c00035 바로가기 바로가기 바로가기
Article Role of endosomal RANKL-LGR4 signaling during osteoclast differentiation Leucine-rich repeat-containing G-protein-coupled receptor 4 (LGR4, also known as GPR48) is a membrane receptor that negatively regulates the RANK signaling cascade during osteoclastogenesis. Traditionally, cell signaling and endocytic membrane trafficking via membrane receptors have been considered distinct processes; however, they are now recognized to be closely and bidirectionally linked. The present study investigated the difference between membrane-bound and endosomal LGR4 signaling and whether the LGR4 signaling pathway influences RANK-RANKL signaling during RANKL-induced osteoclastogenesis. We used CRISPR-Cas9 to create LGR4 conditional knock-out (CKO) in RAW 264.7 cells and Drg2 knockout (KO) in mice to study the impacts of LGR4 and DRG2 on osteoclastogenesis. LGR4 was endocytosed into endosomes after binding to RANKL in RAW 264.7 s osteoclast precursor cells. Within the early endosomes, internalized LGR4 activates LGR4-RANKL signaling. When bound to RANKL, LGR4 is endocytosed and localized in the RAB5-positive endosomes. In Lgr4 CKO RAW 264.7 cells, early endosome signaling was increased and the inhibitory phosphorylation of GSK-3 beta was decreased, both in the whole lysate and endosome fraction. RANKL treatment increased nuclear translocation of NFATC1 in Lgr4 CKO RAW 264.7 cells and Drg2 KO mice. Overall, our results suggested that RANKL-LGR4 signaling is regulated by membrane-to-endosomal trafficking during osteoclastogenesis.Key messagesBone resorption by osteoclasts is essential for bone homeostasis and remodeling. However, the mechanisms underlying the regulation of osteoclastogenesis are not yet fully understood. The present study investigated the difference between membrane-bound and endosomal LGR4 signaling, and whether the LGR4 signaling pathway influences RANK-RANKL signaling during RANKL-induced osteoclastogenesis. Our results suggested that RANKL-LGR4 signaling is regulated by membrane-to-endosomal trafficking during osteoclastogenesis. Kim, Beom Chang; Cho, Yong Jin; Jang, Yuria; Ko, Kang Yeol; Lee, Chang-Moon; Lim, Wonbong Chosun Univ Hosp, Lab Orthoped Res, Gwangju 61453, South Korea; Chosun Univ, Coll Med, Dept Premed Sci, 146 Chosundaegil Dong, Gwangju 61452, South Korea; Kyungpook Natl Univ, KNU Inst Basic Sci, Coll Nat Sci, KNU LAMP Res Ctr, Daegu 41566, South Korea; Chosun Univ, Coll Med, Dept Orthoped Surg, Gwangju 61452, South Korea; Chonnam Natl Univ, Reg Leading Res Ctr, Yeosu 59626, South Korea; Chonnam Natl Univ, Sch Healthcare & Biomed Engn, Yeosu 59626, South Korea 58422281100; 57703148600; 57212510822; 57224504957; 55775343900; 22135620200 wonbong@chosun.ac.kr; JOURNAL OF MOLECULAR MEDICINE-JMM J MOL MED 0946-2716 1432-1440 103 3 SCIE GENETICS & HEREDITY;MEDICINE, RESEARCH & EXPERIMENTAL 2024 4.2 20.7 0 2025-05-07 2 1 Tumor necrosis factor 11 superfamily; Osteoclastogenesis; Osteoporosis; Bone resorption; Leucine-rich repeat-containing G-protein-coupled receptor 4 BONE-RESORPTION; TRAFFICKING Bone resorption; Leucine-rich repeat-containing G-protein-coupled receptor 4; Osteoclastogenesis; Osteoporosis; Tumor necrosis factor 11 superfamily Animals; Cell Differentiation; Endocytosis; Endosomes; Mice; Mice, Knockout; Osteoclasts; Osteogenesis; RANK Ligand; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Signal Transduction; G protein coupled receptor; leucine rich repeat containing G protein coupled receptor 4; osteoclast differentiation factor; unclassified drug; LGR4 protein, mouse; Tnfsf11 protein, mouse; animal cell; Article; cell lysate; endosome; gene knockout; mouse; nonhuman; osteoclast; osteoclastogenesis; osteolysis; protein localization; RAW 264.7 cell line; signal transduction; animal; bone development; cell differentiation; cytology; endocytosis; genetics; knockout mouse; metabolism; osteoclast English 2025 2025-03 10.1007/s00109-025-02523-2 바로가기 바로가기 바로가기 바로가기
Article Complete definition of N→ A transition generalized parton distributions We revisit the definition of the leading-twist chiral-even generalized parton distributions (GPDs) for N -* O baryon transitions. We identify and address deficiencies in previous definitions of the transition GPDs inspired by the transition form factors of the vector and axial vector currents. Through systematic analysis of all possible covariant structures, respecting discrete symmetries and the baryon spinor equations of motion, we derive complete sets of independent structures for the transition matrix elements of the vector and axial vector partonic operators. They contain additional structures proportional to the light-cone vector, corresponding to transition GPDs of vanishing first moment, which were not included in previous parametrizations. Their presence is confirmed independently by the light-front multipole expansion and the cross-channel SO(3) partial-wave analysis of the transition matrix elements. Our analysis provides a complete definition of the N -* O transition GPDs for use in theoretical and phenomenological studies. Kim, June-Young; Semenov-Tian-Shansky, Kirill M.; Won, Ho-Yeon; Son, Sangyeong; Weiss, Christian Theory Ctr, Jefferson Lab, Newport News, VA 23606 USA; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; NRC Kurchatov Inst PNPI, Gatchina 188300, Russia; Natl Res Univ, Higher Sch Econ, St Petersburg 194100, Russia; Ecole Polytech, Inst Polytech Paris, CPHT, CNRS, F-91120 Palaiseau, France PHYSICAL REVIEW D PHYS REV D 2470-0010 2470-0029 111 11 SCIE ASTRONOMY & ASTROPHYSICS;PHYSICS, PARTICLES & FIELDS 2024 5.3 20.8 0 SCATTERING; GAMMA English 2025 2025-06-13 10.1103/m4vj-bkqy 바로가기 바로가기 바로가기
Article Effect of gas density on hydrodynamic characteristics and gas-liquid interfacial area in a 5 kW bubble column reactor This study investigated the impact of gas density on the hydrodynamic characteristics and gas-liquid interfacial area within a bubble column reactor, utilizing air, helium, and tap water. The performance of two types of distributors was compared. Key parameters such as gas holdup, transition gas holdup, transition velocity, bubble size, and specific interfacial area were analyzed across various gas velocities, pressures, and helium concentrations in the air-helium mixtures. As the gas density increased, the gas holdup, transition gas holdup, and transition velocity increased. The porous-plate distributor exhibited better performance metrics than the tubetype distributor. Furthermore, power-law relationships were derived for various parameters in both homogeneous and heterogeneous regimes. In the homogeneous regime, gas velocity exerted a more substantial influence on the gas holdup and specific interfacial area than gas density, whereas in the heterogeneous regime, both factors had nearly equivalent influences. Kim, Daewook; Jang, Jae Jun; Hwang, Byung Wook; Nam, Hyungseok; Lee, Doyeon Korea Inst Energy Res, Daejeon 34129, South Korea; Kyungpook Natl Univ, Sch Mech Engn, Daegu 41566, South Korea; Hanbat Natl Univ, Dept Civil & Environm Engn, Daejeon 34158, South Korea 55569361600; 57553717800; 44461423600; 57190418228; 55881252900 namhs219@knu.ac.kr; dylee82@hanbat.ac.kr; INTERNATIONAL JOURNAL OF MULTIPHASE FLOW INT J MULTIPHAS FLOW 0301-9322 1879-3533 188 SCIE MECHANICS 2024 3.8 20.8 0 2025-05-07 0 0 Bubble column; Gas density; Gas holdup; Flow regime transition; Bubble size; Interfacial area MASS-TRANSFER CHARACTERISTICS; FLOW REGIME TRANSITION; SIZE DISTRIBUTION; TRANSFER COEFFICIENT; ELEVATED PRESSURE; HOLD-UP; PREDICTION Bubble column; Bubble size; Flow regime transition; Gas density; Gas holdup; Interfacial area Bubbles (in fluids); Density of gases; Hydrodynamics; Superfluid helium; Bubble column reactors; Bubble size; Flow regimes transitions; Gas density; Gas hold up; Gas hold-ups; Gas-liquid interfacial areas; Hydrodynamic characteristics; Hydrodynamic gas; Interfacial areas; Bubble columns English 2025 2025-07 10.1016/j.ijmultiphaseflow.2025.105220 바로가기 바로가기 바로가기 바로가기
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