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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Giant Modulation of Magnetoresistance in a Van Der Waals Magnet by In-Plane Current Injection | Efficient magnetization control is a central issue in magnetism and spintronics. Particularly, there are increasing demands for manipulation of magnetic states in van der Waals (vdW) magnets with unconventional functionalities. However, the electrically induced phase transition between ferromagnetic-to-antiferromagnetic states without external magnetic field is yet to be demonstrated. Here, the current-induced magnetic phase transition in a vdW ferromagnet Fe5GeTe2 is reported. Based on magneto-transport measurements and theoretical analysis, it is demonstrated that transition in the interlayer magnetic coupling occurs through vertical voltage drop between layers induced by current which is attributed to high anisotropy of the resistivity caused by the vdW gaps. Such magnetic phase transition results in giant modulation of the longitudinal magnetoresistance from 5% to 170%. The electrical tunability of the magnetic phase in Fe5GeTe2 with current-in-plane geometry opens a path for electric control of magnetic properties, expanding the ability to use vdW magnets for spintronic applications. | Kim, Kwangsu; Ahn, Hyo-Bin; Lee, Seungho; Jeong, Seyeop; Lee, Donghyeon; Lee, Siha; Im, Subin; Kim, Seong Been; Kim, Sung Jong; Park, Jungmin; Lee, Nyun Jong; Koo, Hyun Cheol; An, Kyongmo; Moon, Kyoung-Woong; Kim, Bongjae; Kim, Kyoo; Kim, Kab-Jin; Lee, Changgu; Kim, Kyoung-Whan; Kim, Se Kwon; Park, Tae-Eon; Kim, Sanghoon | Univ Ulsan, Dept Phys, Ulsan 44619, South Korea; Korea Inst Sci & Technol, Ctr Semicond Technol, Seoul 02792, South Korea; Sungkyunkwan Univ, SKKU Adv Inst Nanotechnol, Suwon 16419, South Korea; Argonne Natl Lab, Mat Sci Div, Lemont, IL 60439 USA; Korea Adv Inst Sci & Technol, Dept Phys, Daejeon 34141, South Korea; Korea Univ, KU KIST Grad Sch Converging Sci & Technol, Seoul 02841, South Korea; Univ Ulsan, Energy Harvest Storage Res Ctr, Ulsan 44619, South Korea; Korea Res Inst Stand & Sci, Spin Convergence Res Team, Daejeon 34113, South Korea; Kyungpook Natl Univ, Dept Phys Educ, Daegu 41566, South Korea; KAERI Korea Atom Energy Res Inst, 111 Daedeok Daero, Daejeon 34057, South Korea; Sungkyunkwan Univ, Sch Mech Engn, Suwon 16419, South Korea; Yonsei Univ, Dept Phys, Seoul 03722, South Korea | Park, Jeong Min/AIF-3627-2022; Kim, Se-Kwon/B-8848-2012; Kim, Kyoung-Whan/E-5582-2015; Lee, Jeong-Soo/HMU-9510-2023 | 57216162760; 57216799145; 57216442987; 57343241000; 57222659116; 58375834300; 59532412700; 57216830433; 57195955440; 57209628766; 24724655500; 15049248800; 55541120800; 26422346900; 59510736600; 57214859153; 24314707900; 56955964800; 59722198300; 55928230300; 23036186500; 57189627325 | kwkim@yonsei.ac.kr; sekwonkim@kaist.ac.kr; tepark@kist.re.kr; sanghoon.kim@ulsan.ac.kr; | ADVANCED MATERIALS | ADV MATER | 0935-9648 | 1521-4095 | 37 | 10 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 26.8 | 2.1 | 0 | 2025-05-07 | 0 | 0 | 2D magnet; anisotropic resistivity; antiferromagnet transition; electrical modulation; magnetoresistance; spintronics; van der waals gap | STATES | 2D magnet; anisotropic resistivity; antiferromagnet transition; electrical modulation; magnetoresistance; spintronics; van der waals gap | Antiferromagnetism; Ferromagnetism; Gallium compounds; Germanium alloys; Germanium compounds; Giant magnetoresistance; Magnetic anisotropy; Magnetization; Palladium compounds; Spintronics; 'current; 2d magnet; Anisotropic resistivity; Antiferromagnet transition; Antiferromagnets; Current injections; Electrical modulation; Magnetic-phase transition; Van der Waal; Van der waal gap; anisotropy; article; controlled study; electric potential; geometry; magnet; magnetic field; magnetism; phase transition; Van der Waals forces | English | 2025 | 2025-03 | 10.1002/adma.202414917 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Harnessing Amino Acid Modularity for Programmable Function in Covalent Peptide Assemblies | Covalent peptide assembly leverages robust covalent bonds and dynamic non-covalent interactions to provide enhanced stability and introduce diverse functionalities. Nevertheless, it remains significantly challenging to achieve modular control over the structural diversity and functional complexity while elucidating how specific amino acid sequences contribute to these processes. Here, the systematic encoding of peptide derivative characteristics is demonstrated through amino acid modularity to enable precise control over both the structural diversity and functional complexity in covalent peptide assemblies. By systematically screening single amino acid substitutions in pentapeptides using tyrosine crosslinking, a diverse library of peptide constructs is developed. Each construct is tailored to exhibit distinct properties, including charge repulsion, aggregation-induced quenching, disassembly behavior, and redox responsiveness. The strategic manipulation of sequence composition, both in individual assemblies and combinatorial systems, enables programmable control over the structural diversity and functional complexity. This approach yields various module-specific functions, including frustrated growth, hierarchical hollow architecture formation, affinity enrichment, stimuli-responsive behavior, and fluorescence signal amplification. This work establishes a framework for the design of modular peptide materials with programmable functionalities, advancing the development of next-generation multicomponent peptide assembly technologies characterized by unprecedented complexity and adaptability. | Hur, Yun-Mi; Min, Kyoung-Ik | Kyungpook Natl Univ, Dept Biomed Convergence Sci & Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Adv Bioconvergence, Daegu 41566, South Korea | 57222251131; 25028141900 | kimin@knu.ac.kr; | ADVANCED MATERIALS | ADV MATER | 0935-9648 | 1521-4095 | 37 | 11 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 26.8 | 2.1 | 0 | 2025-05-07 | 1 | 1 | covalent peptide assemblies; multicomponent assembly; sequence-structure-property relationships; single amino acid substitutions; tyrosine | DRUG-DELIVERY; NANOSTRUCTURES; NANOPARTICLES; TYROSINE; DESIGN; TOOL | covalent peptide assemblies; multicomponent assembly; sequence–structure–property relationships; single amino acid substitutions; tyrosine | Amino Acid Sequence; Amino Acids; Oxidation-Reduction; Peptides; Alkylation; Biomineralization; Complexation; Covalent bonds; Crosslinking; Gluing; Hierarchical systems; amino acid; peptide; Amino acid substitution; Covalent peptide assembly; Multicomponent assembly; Sequence structure; Sequence–structure–property relationship; Single amino acid substitution; Structural diversity; Structural-functional; Structure-properties relationships; Tyrosine; amino acid sequence; chemistry; oxidation reduction reaction; Redox reactions | English | 2025 | 2025-03 | 10.1002/adma.202419941 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Retrospective study of Spontaneous Tumors in 32 Pet African Pygmy Hedgehogs, with a Focus on 3 Histiocytic Neoplasms | The number of hedgehogs kept as pets has been increasing worldwide. Tumor occurrence can vary depending on age, living environment, era, and diet. Particularly, pet hedgehogs have distinctly different living conditions and dietary patterns compared to hedgehogs in zoos or wildlife. Previous retrospective studies and reviews on hedgehog tumors have not systematically differentiated their environmental origins. This study examines 34 tumors in 32 privately owned African Pygmy hedgehogs, providing a comprehensive analysis of tumor incidence based on sex, age, malignancy, organ, and location. The research offers valuable insights for veterinary practitioners. Notably, the study focuses on three specific histiocytic neoplasms: histiocytoma, malignant histiocytoma, and malignant fibrous histiocytoma. By presenting an updated report on tumor incidence in privately owned hedgehogs, this research aims to guide diagnosis and treatment strategies for pathologists and small exotic animal veterinary practitioners. | Lee, Eun-Joo | Kyungpook Natl Univ, Coll Vet Med, Dept Vet Pathol, 80 Daehakro, Daegu 41566, South Korea; Harvard Med Sch, Brigham Womens Hosp, Dept Orthopaed, 60 Fenwood Rd, Boston, MA 02115, USA | 58363110000 | elee22@bidmc.harvard.edu; | PAKISTAN VETERINARY JOURNAL | PAK VET J | 0253-8318 | 2074-7764 | 45 | 1 | SCIE | VETERINARY SCIENCES | 2024 | 5.4 | 2.1 | 0 | 2025-05-07 | 0 | 0 | African pygmy hedgehog; Hedgehog tumors; Histiocytic neoplasm; Privately owned hedgehog; Tumor incidence | ATELERIX-ALBIVENTRIS; SARCOMA | African pygmy hedgehog; Hedgehog tumors; Histiocytic neoplasm; Privately owned hedgehog; Tumor incidence | abdominal cavity; adenocarcinoma; angiosarcoma; animal cell; animal tissue; anorexia; Article; Atelerix albiventris; cancer incidence; differential diagnosis; endometrium carcinoma; female; fibrosarcoma; granulosa cell tumor; hemangioendothelioma; hemangioma; histiocytoma; histopathology; immunohistochemistry; leiomyosarcoma; lipoma; liposarcoma; male; malignant fibrous histiocytoma; myxosarcoma; nonhuman; papilloma; pet animal; remission; retrospective study; rhabdomyosarcoma | English | 2025 | 2025 | 10.29261/pakvetj/2025.139 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Rolling the Dice with Light Competition: Introducing a True Random Number Generator Powered by Photo-Induced Polarity Current | The pursuit of hardware-based security solutions has highlighted the true random number generator (TRNG). Various physical phenomena, from noise generation to quantum physics complexities, have been explored for random number generation. The arc discharge light-induced TRNG (ALTRNG) is introduced, featuring wavelength-dependent photocurrent generation and arc discharge irradiation. A bipolar photo-responsive photodetector (BPPD) differentiates "1" and "0" states, producing highly random bits validated by the National Institute of Standards and Technology (NIST) 15 tests. The BPPD's response to deep-ultraviolet (DUV) and blue light enables distinct photocurrent generation under arc discharge illumination. The ALTRNG generates true random signals, yielding bit streams with unpredictability, uniform distribution, and stability. With a readout circuit achieving 2-kbps, wireless random number transmission is demonstrated, highlighting potential for secure password systems and artificial X-ray image generation. | Park, Taehyun; Seo, Juhyung; Kim, Namju; Kim, Chaehyun; Kim, Yeong Jae; Kim, Hyeonghun; Kim, Hyun Ho; Oh, Seyong; Kim, Dong Chan; Son, Donghee; Hur, Jaehyun; Kim, Young-Joon; Jang, Byung Chul; Yoo, Hocheon | Gachon Univ, Dept Semicond Engn, Seongnam Daero 1342, Seongnam 13120, Gyeonggi Do, South Korea; Hanyang Univ, Dept Elect Engn, 222 Wangsimni Ro, Seoul 04763, South Korea; Gachon Univ, Dept Elect Engn, 1342 Seongnam Daero, Seongnam 13120, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Elect Engn, 80 Daehak Ro, Daegu 41566, South Korea; Korea Inst Ceram Engn & Technol KICET, Ceram Total Solut Ctr, 3321 Gyeongchung Daero, Icheon 17303, Gyeonggi Do, South Korea; Kumoh Natl Inst Technol, Sch Mat Sci & Engn, Dept Energy Engn Convergence, Gumi 39177, South Korea; Hanyang Univ ERICA, Div Elect Engn, Ansan 15588, South Korea; Gachon Univ, Dept Chem & Biol Engn, 1342 Seongnam Daero, Seongnam 13120, Gyeonggi Do, South Korea; Sungkyunkwan Univ SKKU, Dept Elect & Comp Engn, Suwon 16419, South Korea | Jang, Byung Chul/GYV-0656-2022; Son, Donghee/KLC-8907-2024; Kim, Hyun/AAA-7228-2019; Yoo, Hocheon/ABZ-6637-2022; Kim, Dong Chan/GRX-9307-2022 | 57211288149; 57223360876; 58119785900; 57778305700; 57830611600; 59868961300; 55808014500; 57189443832; 56651296900; 56076777700; 36240634900; 55699531100; 9238827900; 56637576900 | jhhur@gachon.ac.kr; youngkim@gachon.ac.kr; bc.jang@knu.ac.kr; hocheon@hanyang.ac.kr; | ADVANCED MATERIALS | ADV MATER | 0935-9648 | 1521-4095 | 37 | 14 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 26.8 | 2.1 | 0 | 2025-05-07 | 0 | 0 | arc discharge; artificial intelligence training; bipolar photo response; security devices; TRNG | COMPACT | arc discharge; artificial intelligence training; bipolar photo response; security devices; TRNG | Antiknock rating; Authentication; Digital arithmetic; Laser beams; Medium access control; Noise generators; Number theory; Photodetectors; Arc discharge; Artificial intelligence training; Bipolar photo response; Discharge light; Light-induced; Photoresponses; Random number generators; Security devices; True random number generator; True randoms; article; artificial intelligence; bipolar disorder; blue light; competition; controlled study; electric potential; human; illumination; irradiation; light; noise; physical phenomena; ultraviolet radiation; X ray; X ray analysis; Random number generation | English | 2025 | 2025-04 | 10.1002/adma.202419579 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Soft-Actuated Cuff Electrodes with Minimal Contact for Bidirectional Peripheral Interfaces | Neural interfaces with embedded electrical functions, such as cuff electrodes, are essential for monitoring and stimulating peripheral nerves. Still, several challenges remain with cuff electrodes because sutured devices can damage the nerve by high pressure and the secured contact of electrodes with the nerve is hard to accomplish, which however is essential in maintaining electrical performance. Here, a sutureless soft-actuated cuff electrodes (SACE) that can envelop the nerve conveniently by creating a bent shape controlled upon fluid injection, is introduced. Moreover, fluid injection protrudes part of the device where electrodes are formed, thereby achieving minimized, soft but secure contact between the electrodes and the nerve. In vivo results demonstrate the successful recording and stimulation of peripheral nerves over time up to 6 weeks. While securing contact with the nerve, the implanted electrodes can preserve the nerve intact with no reduction in blood flow, thereby indicating only minimal compressive force applied to the nerve. The SACE is expected to be a promising tool for recording and stimulation of peripheral nerves toward bidirectional neuroprostheses. | Moon, Hyunmin; Park, Byungwook; Chou, Namsun; Park, Ki-Su; Lee, Sanghoon; Kim, Sohee | Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept Robot & Mechatron Engn, Daegu 42988, South Korea; MIT, Dept Mech Engn, Cambridge, MA 02139 USA; Korea Brain Res Inst, Emot Cognit & Behav Res Grp, Daegu 41062, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu 41944, South Korea | Chou, Namsun/AAS-3841-2020; Moon, HyunMin/R-7853-2019 | 57191245161; 57223900884; 43061070600; 55932363100; 57216696166; 55958147000 | soheekim@dgist.ac.kr; | ADVANCED MATERIALS | ADV MATER | 0935-9648 | 1521-4095 | 37 | 5 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 26.8 | 2.1 | 2.53 | 2025-05-07 | 1 | 1 | bidirectional interface; fluid injection; minimal contact; soft actuation; soft-actuated cuff electrodes (SACE); sutureless cuff electrode | NERVE STIMULATION; PHASE | bidirectional interface; fluid injection; minimal contact; soft actuation; soft-actuated cuff electrodes (SACE); sutureless cuff electrode | Animals; Electric Stimulation; Electrodes; Electrodes, Implanted; Equipment Design; Peripheral Nerves; Electrodes; Functional neural stimulation; Neurons; Bidirectional interface; Cuff electrode; Fluid injections; Minimal contact; Peripheral interfaces; Peripheral nerves; Soft actuation; Soft-actuated cuff electrode; Sutureless cuff electrode; animal; electrode; electrode implant; electrostimulation; equipment design; peripheral nerve; physiology | English | 2025 | 2025-02 | 10.1002/adma.202409942 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Ultrafast and Universal Synthetic Route for Nanostructured Transition Metal Oxides Directly Grown on Substrates | Nanostructured transition metal oxides (NTMOs) have consistently piqued scientific interest for several decades due to their remarkable versatility across various fields. More recently, they have gained significant attention as materials employed for energy storage/harvesting devices as well as electronic devices. However, mass production of high-quality NTMOs in a well-controlled manner still remains challenging. Here, a universal, ultrafast, and solvent-free method is presented for producing highly crystalline NTMOs directly onto target substrates. The findings reveal that the growth mechanism involves the solidification of condensed liquid-phase TMO microdroplets onto the substrate under an oxygen-rich ambient condition. This enables a continuous process under ambient air conditions, allowing for processing within just a few tens of seconds per sample. Finally, it is confirmed that the method can be extended to the synthesis of various NTMOs and their related compounds. | Lim, Si Heon; Kim, Geunwoo; Cho, Sungjin; Kim, Yeong Kwon; Ko, Eun Bee; Choi, Seon Yeon; Heo, Jung A.; Kim, Daegun; Yoo, Hocheon; Lee, So-Yeon; Kim, Yongjoo; Cha, Pil-Ryung; Lee, Dong Yun; Lee, Sunghun; Jang, Byung Chul; Kim, Yeonhoo; Kim, Hyun Ho | Kumoh Natl Inst Technol, Sch Mat Sci & Engn, Gumi 39177, South Korea; Kumoh Natl Inst Technol, Dept Energy Engn Convergence, Gumi 39177, South Korea; Korea Univ, Dept Mat Sci & Engn, Seoul 02841, South Korea; Korea Res Inst Stand & Sci KRISS, Strateg Technol Res Inst, Daejeon 34113, South Korea; Univ Sci & Technol UST, Appl Measurement Sci, Daejeon 34113, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Gachon Univ, Sch Chem Biol & Battery Engn, Seongnam 13120, South Korea; Hanyang Univ, Dept Elect Engn, 222 Wangsimni Ro, Seoul 04763, South Korea; Kookmin Univ, Sch Mat Sci & Engn, Seoul 02707, South Korea; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu 41566, South Korea; Daegu Gyeongbuk Inst Sci & Technol DGIST, Convergence Res Inst, Div Nanotechnol, Daegu 42988, South Korea | Jang, Byung Chul/GYV-0656-2022; Kim, Hyun/AAA-7228-2019 | 58510465700; 59042530300; 59249837800; 58120005900; 58538730000; 58515326700; 59544710300; 59618872300; 56637576900; 55827513900; 57203809745; 7004656771; 59510702000; 57192194223; 59818720500; 57190740415; 55808014500 | kimhh@kumoh.ac.kr; | ADVANCED MATERIALS | ADV MATER | 0935-9648 | 1521-4095 | 37 | 16 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 26.8 | 2.1 | 0 | 2025-05-07 | 0 | 0 | gas sensors; nanostructured transition metal oxide; physical unclonable functions, ultrafast synthesis; universal synthesis | ELECTRODES; OXIDATION; ENERGY | gas sensors; nanostructured transition metal oxide; physical unclonable functions, ultrafast synthesis; universal synthesis | Gallium phosphide; Indium phosphide; Nanoclay; Synthetic metals; metal oxide; oxygen; solvent; transition element; Energy; Gas-sensors; Nano-structured; Nanostructured transition metal oxide; Physical unclonable function, ultrafast synthesis; Synthetic routes; Transition-metal oxides; Ultra-fast; Ultrafast synthesis; Universal synthesis; ambient air; article; continuous process; electronic device; gas; liquid; nonhuman; sensor; synthesis; Transition metal oxides | English | 2025 | 2025-04 | 10.1002/adma.202418407 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Review | Overview of high-density QCD studies with the CMS experiment at the LHC | We review key measurements performed by CMS in the context of its heavy ion physics program, using event samples collected in 2010-2018 with several collision systems and energies. These studies provide detailed macroscopic and microscopic probes of the quark-gluon plasma (QGP) created at the LHC energies, a medium characterized by the highest temperature and smallest baryon-chemical potential ever reached in the laboratory. Numerous observables related to high-density quantum chromodynamics (QCD) were studied, leading to some of the most impactful and qualitatively novel results in the 40-year history of the field. Using a dedicated high-multiplicity trigger in the first pp run, CMS discovered that small collision systems can exhibit signs of collectivity, a generic phenomenon with significant implications and presently understood to affect essentially all soft physics processes. This observation opened new paths to understand how fluidity and plasma properties emerge in QCD matter as a function of system size. Measurements of jet quenching have reached a completely new level of detail by directly assessing, for the first time, the medium modification of parton showers, as opposed to simply observing leading hadrons or di-hadrons. The first fully reconstructed beauty hadron and heavy-flavor jet nuclear modifications were also measured. The large size of the event samples, the precision of the measurements, and the extension of the probed kinematical phase space, allowed many other hard probes of the QGP medium to be explored in detail, leading to multiple groundbreaking findings. In particular, the seminal measurements of bottomonium suppression patterns answer fundamental questions that have been actively pursued, both theoretically and experimentally, by the community since the mid-1980s. We conclude by outlining the opportunities offered by the continuation of this physics program at the LHC. (c) 2024 CERN for the benefit of the CMS Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | Hayrapetyan, A.; Tumasyan, A.; Adam, W.; Andrejkovic, J. W.; Bergauer, T.; Chatterjee, S.; Damanakis, K.; Dragicevic, M.; Hussain, P. S.; Jeitler, M.; Krammer, N.; Li, A.; Liko, D.; Mikulec, I.; Schieck, J.; Schoefbeck, R.; Schwarz, D.; Sonawane, M.; Templ, S.; Waltenberger, W.; Wulz, C. -E.; Darwish, M. R.; Janssen, T.; Van Mechelen, P.; Bols, E. S.; D'Hondt, J.; Dansana, S.; De Moor, A.; Delcourt, M.; El Faham, H.; Lowette, S.; Makarenko, I.; Mueller, D.; Tavernier, S.; Tytgat, M.; Van Onsem, G. P.; Van Putte, S.; Vannerom, D.; Clerbaux, B.; Das, A. K.; De Lentdecker, G.; Evard, H.; Favart, L.; Gianneios, P.; Hohov, D.; Jaramillo, J.; Khalilzadeh, A.; Khan, F. A.; Lee, K.; Mahdavikhorrami, M.; Malara, A.; Paredes, S.; Thomas, L.; Vanden Bemden, M.; Vander Velde, C.; Vanlaer, P.; De Coen, M.; Dobur, D.; Hong, Y.; Knolle, J.; Lambrecht, L.; Mestdach, G.; Amarilo, K. Mota; Rendon, C.; Samalan, A.; Skovpen, K.; Van den Bossche, N.; van der Linden, J.; Wezenbeek, L.; Benecke, A.; Bethani, A.; Bruno, G.; Caputo, C.; Delaere, C.; Donertas, I. S.; Giammanco, A.; Jain, Sa.; Lemaitre, V.; Lidrych, J.; Mastrapasqua, P.; Mondal, K.; Tran, T. T.; Wertz, S.; Alves, G. A.; Coelho, E.; Hensel, C.; Menezes De Oliveira, T.; Moraes, A.; Rebello Teles, P.; Soeiro, M.; Alda Junior, W. L.; Alves Gallo Pereira, M.; Barroso Ferreira Filho, M.; Brandao Malbouisson, H.; Carvalho, W.; Chinellato, J.; Da Costa, E. M.; Da Silveira, G. G.; De Jesus Damiao, D.; Fonseca De Souza, S.; Gomes De Souza, R.; Martins, J.; Mora Herrera, C.; Mundim, L.; Nogima, H.; Pinheiro, J. P.; Santoro, A.; Sznajder, A.; Thiel, M.; Vilela Pereira, A.; Bernardes, C. A.; Calligaris, L.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Maietto Silverio, I.; Mercadante, P. G.; Novaes, S. F.; Orzari, B.; Padula, Sandra S.; Aleksandrov, A.; Antchev, G.; Hadjiiska, R.; Iaydjiev, P.; Misheva, M.; Shopova, M.; Sultanov, G.; Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P.; Petrov, A.; Shumka, E.; Keshri, S.; Thakur, S.; Cheng, T.; Javaid, T.; Yuan, L.; Hu, Z.; Liu, J.; Yi, K.; Chen, G. M.; Chen, H. S.; Chen, M.; Iemmi, F.; Jiang, C. H.; Kapoor, A.; Liao, H.; Liu, Z. -A.; Sharma, R.; Song, J. N.; Tao, J.; Wang, C.; Wang, J.; Wang, Z.; Zhang, H.; Agapitos, A.; Ban, Y.; Levin, A.; Li, C.; Li, Q.; Mao, Y.; Qian, S. J.; Sun, X.; Wang, D.; Yang, H.; Zhang, L.; Zhou, C.; Yang, S.; You, Z.; Jaffel, K.; Lu, N.; Bauer, G.; Gao, X.; Leggat, D.; Okawa, H.; Lin, Z.; Lu, C.; Xiao, M.; Avila, C.; Barbosa Trujillo, D. A.; Cabrera, A.; Florez, C.; Fraga, J.; Reyes Vega, J. A.; Mejia Guisao, J.; Ramirez, F.; Rodriguez, M.; Ruiz Alvarez, J. D.; Giljanovic, D.; Godinovic, N.; Lelas, D.; Sculac, A.; Kovac, M.; Sculac, T.; Bargassa, P.; Brigljevic, V.; Chitroda, B. K.; Ferencek, D.; Jakovcic, K.; Mishra, S.; Starodumov, A.; Susa, T.; Attikis, A.; Christoforou, K.; Konstantinou, S.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Saka, H.; Stepennov, A.; Finger, M.; Finger, M., Jr.; Kveton, A.; Ayala, E.; Carrera Jarrin, E.; Abdalla, H.; Assran, Y.; Lotfy, A.; Mahmoud, M. A.; Ehataht, K.; Kadastik, M.; Lange, T.; Nandan, S.; Nielsen, C.; Pata, J.; Raidal, M.; Tani, L.; Veelken, C.; Kirschenmann, H.; Osterberg, K.; Voutilainen, M.; Bharthuar, S.; Brucken, E.; Garcia, F.; Kallonen, K. T. S.; Kinnunen, R.; Lampen, T.; Lassila-Perini, K.; Lehti, S.; Linden, T.; Martikainen, L.; Myllymaki, M.; Rantanen, M. M.; Siikonen, H.; Tuominen, E.; Tuominiemi, J.; Luukka, P.; Petrow, H.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Faure, J. L.; Ferri, F.; Ganjour, S.; Gras, P.; de Monchenault, G. Hamel; Lohezic, V.; Malcles, J.; Rander, J.; Rosowsky, A.; Sahin, M. O.; Savoy-Navarro, A.; Simkina, P.; Titov, M.; Tornago, M.; Barrera, C. Baldenegro; Beaudette, F.; Perraguin, A. Buchot; Busson, P.; Cappati, A.; Charlot, C.; Chiusi, M.; Damas, F.; Davignon, O.; De Wit, A.; Alves, B. A. Fontana Santos; Ghosh, S.; Gilbert, A.; de Cassagnac, R. Granier; Hakimi, A.; Harikrishnan, B.; Kalipoliti, L.; Liu, G.; Motta, J.; Nguyen, M.; Ochando, C.; Portales, L.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Tarabini, A.; Vernazza, E.; Zabi, A.; Zghiche, A.; Agram, J. -L.; Andrea, J.; Apparu, D.; Bloch, D.; Brom, J. -M.; Chabert, E. C.; Collard, C.; Falke, S.; Goerlach, U.; Grimault, C.; Haeberle, R.; Le Bihan, A. -C.; Meena, M.; Saha, G.; Sessini, M. A.; Van Hove, P.; Beauceron, S.; Blancon, B.; Boudoul, G.; Chanon, N.; Choi, J.; Contardo, D.; Depasse, P.; Dozen, C.; El Mamouni, H.; Fay, J.; Gascon, S.; Gouzevitch, M.; Greenberg, C.; Grenier, G.; Ille, B.; Laktineh, I. B.; Lethuillier, M.; Mirabito, L.; Perries, S.; Purohit, A.; Vander Donckt, M.; Verdier, P.; Xiao, J.; Lomidze, I.; Toriashvili, T.; Tsamalaidze, Z.; Botta, V.; Feld, L.; Klein, K.; Lipinski, M.; Meuser, D.; Pauls, A.; Roewert, N.; Teroerde, M.; Diekmann, S.; Dodonova, A.; Eich, N.; Eliseev, D.; Engelke, F.; Erdmann, J.; Erdmann, M.; Fackeldey, P.; Fischer, B.; Hebbeker, T.; Hoepfner, K.; Ivone, F.; Jung, A.; Lee, M. Y.; Mausolf, F.; Merschmeyer, M.; Meyer, A.; Mukherjee, S.; Noll, D.; Nowotny, F.; Pozdnyakov, A.; Rath, Y.; Redjeb, W.; Rehm, F.; Reithler, H.; Sarkar, U.; Sarkisovi, V.; Schmidt, A.; Sharma, A.; Spah, J. L.; Stein, A.; Torres Da Silva De Araujo, F.; Vigilante, L.; Wiedenbeck, S.; Zaleski, S.; Dziwok, C.; Fluegge, G.; Ahmad, W. Haj; Kress, T.; Nowack, A.; Pooth, O.; Stahl, A.; Ziemons, T.; Zotz, A.; Petersen, H. Aarup; Martin, M. Aldaya; Alimena, J.; Amoroso, S.; An, Y.; Baxter, S.; Bayatmakou, M.; Gonzalez, H. Becerril; Behnke, O.; Belvedere, A.; Bhattacharya, S.; Blekman, F.; Borras, K.; Campbell, A.; Cardini, A.; Cheng, C.; Colombina, F.; Rodriguez, S. Consuegra; Silva, G. Correia; De Silva, M.; Eckerlin, G.; Eckstein, D.; Banos, L. I. Estevez; Filatov, O.; Gallo, E.; Geiser, A.; Giraldi, A.; Guglielmi, V.; Guthoff, M.; Hinzmann, A.; Jafari, A.; Jeppe, L.; Jomhari, N. Z.; Kaech, B.; Kasemann, M.; Kleinwort, C.; Kogler, R.; Komm, M.; Kruecker, D.; Lange, W.; Pernia, D. Leyva; Lipka, K.; Lohmann, W.; Mankel, R.; Melzer-Pellmann, I. -A.; Morentin, M. Mendizabal; Meyer, A. B.; Milella, G.; Mussgiller, A.; Nair, L. P.; Nuernberg, A.; Otarid, Y.; Park, J.; Adan, D. Perez; Ranken, E.; Raspereza, A.; Lopes, B. Ribeiro; Ruebenach, J.; Saggio, A.; Scham, M.; Schnake, S.; Schuetze, P.; Schwanenberger, C.; Selivanova, D.; Sharko, K.; Shchedrolosiev, M.; Ricardo, R. E. Sosa; Stafford, D.; Vazzoler, F.; Barroso, A. Ventura; Walsh, R.; Wen, Y.; Wichmann, K.; Wiens, L.; Wissing, C.; Yang, Y.; Santos, A. Zimermmane Castro; Albrecht, A.; Albrecht, S.; Antonello, M.; Bein, S.; Benato, L.; Bollweg, S.; Bonanomi, M.; Connor, P.; Eich, M.; El Morabit, K.; Fischer, Y.; Garbers, C.; Garutti, E.; Grohsjean, A.; Haller, J.; Jabusch, H. R.; Kasieczka, G.; Keicher, P.; Klanner, R.; Korcari, W.; Kramer, T.; Kutzner, V.; Labe, F.; Lange, J.; Lobanov, A.; Matthies, C.; Mehta, A.; Moureaux, L.; Mrowietz, M.; Nigamova, A.; Nissan, Y.; Paasch, A.; Rodriguez, K. J. Pena; Quadfasel, T.; Raciti, B.; Rieger, M.; Savoiu, D.; Schindler, J.; Schleper, P.; Schroeder, M.; Schwandt, J.; Sommerhalder, M.; Stadie, H.; Steinbrueck, G.; Tews, A.; Wolf, M.; Brommer, S.; Burkart, M.; Butz, E.; Chwalek, T.; Dierlamm, A.; Droll, A.; Faltermann, N.; Giffels, M.; Gottmann, A.; Hartmann, F.; Hofsaess, R.; Horzela, M.; Husemann, U.; Kieseler, J.; Klute, M.; Koppenhoefer, R.; Lawhorn, J. M.; Link, M.; Lintuluoto, A.; Maier, S.; Mitra, S.; Mormile, M.; Mueller, Th.; Neukum, M.; Oh, M.; Pfeffer, E.; Presilla, M.; Quast, G.; Rabbertz, K.; Regnery, B.; Shadskiy, N.; Shvetsov, I.; Simonis, H. J.; Toms, M.; Trevisani, N.; Von Cube, R. F.; Wassmer, M.; Wieland, S.; Wittig, F.; Wolf, R.; Zuo, X.; Anagnostou, G.; Daskalakis, G.; Kyriakis, A.; Papadopoulos, A.; Stakia, A.; Kontaxakis, P.; Melachroinos, G.; Panagiotou, A.; Papavergou, I.; Paraskevas, I.; Saoulidou, N.; Theofilatos, K.; Tziaferi, E.; Vellidis, K.; Zisopoulos, I.; Bakas, G.; Chatzistavrou, T.; Karapostoli, G.; Kousouris, K.; Papakrivopoulos, I.; Siamarkou, E.; Tsipolitis, G.; Zacharopoulou, A.; Adamidis, K.; Bestintzanos, I.; Evangelou, I.; Foudas, C.; Kamtsikis, C.; Katsoulis, P.; Kokkas, P.; Kioseoglou, P. G. Kosmoglou; Manthos, N.; Papadopoulos, I.; Strologas, J.; Bartok, M.; Hajdu, C.; Horvath, D.; Marton, K.; Sikler, F.; Veszpremi, V.; Csanad, M.; Farkas, K.; Gadallah, M. M. A.; Kadlecsik, A.; Major, P.; Mandal, K.; Pasztor, G.; Radl, A. J.; Veres, G. I.; Raics, P.; Ujvari, B.; Zilizi, G.; Bencze, G.; Czellar, S.; Molnar, J.; Szillasi, Z.; Csorgo, T.; Nemes, F.; Novak, T.; Babbar, J.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Chaudhary, G.; Chauhan, S.; Dhingra, N.; Kaur, A.; Kaur, H.; Kaur, M.; Kumar, S.; Sandeep, K.; Sheokand, T.; Singh, J. B.; Singla, A.; Ahmed, A.; Bhardwaj, A.; Chhetri, A.; Choudhary, B. C.; Kumar, A.; Naimuddin, M.; Ranjan, K.; Saumya, S.; Baradia, S.; Barman, S.; Dutta, S.; Sarkar, S.; Ameen, M. M.; Behera, P. K.; Behera, S. C.; Chatterjee, S.; Jana, P.; Kalbhor, P.; Komaragiri, J. R.; Kumar, D.; Pujahari, P. R.; Saha, N. R.; Sharma, A.; Sikdar, A. K.; Verma, S.; Dugad, S.; Kumar, M.; Mohanty, G. B.; Suryadevara, P.; Bala, A.; Banerjee, S.; Chatterjee, R. M.; Dewanjee, R. K.; Guchait, M.; Jain, Sh.; Jaiswal, A.; Karmakar, S.; Kumar, S.; Majumder, G.; Mazumdar, K.; Parolia, S.; Thachayath, A.; Bahinipati, S.; Kar, C.; Maity, D.; Mal, P.; Mishra, T.; Bindhu, V. K. Muraleedharan Nair; Naskar, K.; Nayak, A.; Sadangi, P.; Saha, P.; Swain, S. K.; Varghese, S.; Vats, D.; Acharya, S.; Alpana, A.; Dube, S.; Gomber, B.; Kansal, B.; Laha, A.; Sahu, B.; Sharma, S.; Vaish, K. Y.; Bakhshiansohi, H.; Khazaie, E.; Zeinali, M.; Chenarani, S.; Etesami, S. M.; Khakzad, M.; Najafabadi, M. Mohammadi; Grunewald, M.; Abbrescia, M.; Aly, R.; Colaleo, A.; Creanza, D.; D'Anzi, B.; De Filippis, N.; De Palma, M.; Di Florio, A.; Elmetenawee, W.; Fiore, L.; Iaselli, G.; Louka, M.; Maggi, G.; Maggi, M.; Margjeka, I.; Mastrapasqua, V.; My, S.; Nuzzo, S.; Pellecchia, A.; Pompili, A.; Pugliese, G.; Radogna, R.; Ramirez-Sanchez, G.; Ramos, D.; Ranieri, A.; Silvestris, L.; Simone, F. M.; Sozbilir, U.; Stamerra, A.; Venditti, R.; Verwilligen, P.; Zaza, A.; Abbiendi, G.; Battilana, C.; Bonacorsi, D.; Borgonovi, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Cuffiani, M.; Dallavalle, G. M.; Diotalevi, T.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Giommi, L.; Guiducci, L.; Lo Meo, S.; Lunerti, L.; Marcellini, S.; Masetti, G.; Navarria, F. L.; Perrotta, A.; Primavera, F.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Costa, S.; Di Mattia, A.; Potenza, R.; Tricomi, A.; Tuve, C.; Assiouras, P.; Barbagli, G.; Bardelli, G.; Camaiani, B.; Cassese, A.; Ceccarelli, R.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Kello, T.; Latino, G.; Lenzi, P.; Lizzo, M.; Meschini, M.; Paoletti, S.; Papanastassiou, A.; Sguazzoni, G.; Viliani, L.; Benussi, L.; Bianco, S.; Meola, S.; Piccolo, D.; Chatagnon, P.; Ferro, F.; Robutti, E.; Tosi, S.; Benaglia, A.; Boldrini, G.; Brivio, F.; Cetorelli, F.; De Guio, F.; Dinardo, M. E.; Dini, P.; Gennai, S.; Gerosa, R.; Ghezzi, A.; Govoni, P.; Guzzi, L.; Lucchini, M. T.; Malberti, M.; Malvezzi, S.; Massironi, A.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Pinolini, B. S.; Ragazzi, S.; de Fatis, T. Tabarelli; Zuolo, D.; Buontempo, S.; Cagnotta, A.; Carnevali, F.; Cavallo, N.; Fabozzi, F.; Iorio, A. O. M.; Lista, L.; Paolucci, P.; Rossi, B.; Sciacca, C.; Ardino, R.; Azzi, P.; Bacchetta, N.; Benettoni, M.; Bisello, D.; Bortignon, P.; Bortolato, G.; Bragagnolo, A.; Carlin, R.; Checchia, P.; Dorigo, T.; Gasparini, F.; Gasparini, U.; Lusiani, E.; Margoni, M.; Marini, F.; Migliorini, M.; Pazzini, J.; Ronchese, P.; Rossin, R.; Simonetto, F.; Strong, G.; Tosia, M.; Triossi, A.; Ventura, S.; Yarar, H.; Zanetti, M.; Zotto, P.; Zucchetta, A.; Zumerle, G.; Abu Zeid, S.; Aime, C.; Braghieri, A.; Calzaferri, S.; Fiorina, D.; Montagna, P.; Re, V.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Ajmal, S.; Bilei, G. M.; Ciangottini, D.; Fano, L.; Magherini, M.; Mantovani, G.; Mariani, V.; Menichelli, M.; Moscatelli, F.; Rossi, A.; Santocchia, A.; Spiga, D.; Tedeschi, T.; Asenov, P.; Azzurri, P.; Bagliesi, G.; Bhattacharya, R.; Bianchini, L.; Boccali, T.; Bossini, E.; Bruschini, D.; Castaldi, R.; Ciocci, M. A.; Cipriani, M.; D'Amante, V.; Dell'Orso, R.; Donato, S.; Giassi, A.; Ligabue, F.; Figueiredo, D. Matos; Messineo, A.; Musich, M.; Palla, F.; Rizzi, A.; Rolandi, G.; Chowdhury, S. Roy; Sarkar, T.; Scribano, A.; Spagnolo, P.; Tenchini, R.; Tonellia, G.; Turini, N.; Venturi, A.; Verdini, P. G.; Barria, P.; Basile, C.; Campana, M.; Cavallari, F.; Mendez, L. Cunqueiro; Del Re, D.; Di Marco, E.; Diemoz, M.; Errico, F.; Longo, E.; Meridiani, P.; Mijuskovic, J.; Organtini, G.; Pandolfi, F.; Paramatti, R.; Quaranta, C.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Soffi, L.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bartosik, N.; Bellan, R.; Bellora, A.; Biino, C.; Borca, C.; Cartiglia, N.; Costa, M.; Covarelli, R.; Demaria, N.; Finco, L.; Grippo, M.; Kiani, B.; Legger, F.; Luongo, F.; Mariotti, C.; Markovic, L.; Maselli, S.; Mecca, A.; Migliore, E.; Monteno, M.; Mulargia, R.; Obertino, M. M.; Ortona, G.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Ruspa, M.; Siviero, F.; Sola, V.; Solano, A.; Staiano, A.; Tarricone, C.; Trocino, D.; Umoret, G.; Vlasov, E.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; De Leo, K.; Della Ricca, G.; Dogra, S.; Hong, J.; Huh, C.; Kim, B.; Kim, D. H.; Lee, H.; Lee, S. W.; Moon, C. S.; Oh, Y. D.; Ryu, M. S.; Sekmen, S.; Yang, Y. C.; Kim, M. S.; Bak, G.; Gwak, P.; Kim, H.; Moon, D. H.; Asilar, E.; Kim, D.; Kim, T. J.; Merlin, J. A.; Choi, S.; Han, S.; Hong, B.; Lee, K.; Lee, K. S.; Lee, S.; Park, S. K.; Yoo, J.; Goh, J.; Yang, S.; Kim, H. S.; Kim, Y.; Almond, J.; Bhyun, J. H.; Choi, J.; Jun, W.; Ko, S.; Kwon, H.; Lee, J.; Oh, B. H.; Oh, S. B.; Seo, H.; Yang, U. K.; Yoon, I.; Jang, W.; Kang, D. Y.; Kang, Y.; Kim, S.; Ko, B.; Lee, J. S. H.; Lee, Y.; Park, I. C.; Roh, Y.; Watson, I. J.; Ha, S.; Yoo, H. D.; Choi, M.; Kim, M. R.; Yu, I.; Beyrouthy, T.; Dreimanis, K.; Gaile, A.; Pikurs, G.; Potrebko, A.; Seidel, M.; Veckalns, V.; Strautnieks, N. R.; Ambrozas, M.; Juodagalvis, A.; Rinkevicius, A.; Tamulaitis, G.; Bin Norjoharuddeen, N.; Yusuff, I.; Zolkapli, Z.; Barajas Ibarria, J. P.; Benitez, J. F.; Castaneda Hernandez, A.; Encinas Acosta, H. A.; Gallegos Marinez, L. G.; Leon Coello, M.; Murillo Quijada, J. A.; Sehrawat, A.; Valencia Palomo, L.; Ayala, G.; Castilla-Valdez, H.; Crotte Ledesma, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Lopez-Fernandez, R.; Mondragon Herrera, C. A.; Sanchez Hernandez, A.; Oropeza Barrera, C.; Ramirez Garcia, M.; Bautista, I.; Pedraza, I.; Salazar Ibarguen, H. A.; Uribe Estrada, C.; Bubanja, I.; Raicevic, N.; Butler, P. H.; Ahmad, A.; Asghar, M. I.; Awais, A.; Awan, M. I. M.; Hoorani, H. R.; Khan, W. A.; Avati, V.; Grzanka, L.; Malawski, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Gorski, M.; Kazana, M.; Szleper, M.; Zalewski, P.; Bunkowski, K.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Muhammad, A.; Pozniak, K.; Zabolotny, W.; Araujo, M.; Bastos, D.; Beirao Da Cruz E Silva, C.; Boletti, A.; Bozzo, M.; Camporesi, T.; Da Molin, G.; Faccioli, P.; Gallinaro, M.; Hollar, J.; Leonardo, N.; Niknejad, T.; Petrilli, A.; Pisano, M.; Seixas, J.; Varela, J.; Wulff, J. W.; Adzic, P.; Milenovic, P.; Dordevic, M.; Milosevic, J.; Rekovic, V.; Aguilar-Benitez, M.; Alcaraz Maestre, J.; Bedoya, Cristina F.; Cepeda, M.; Cerrada, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Escalante Del Valle, A.; Fernandez Del Val, D.; Fernandez Ramos, J. P.; Flix, J.; Fouz, M. C.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Moran, D.; Morcillo Perez, C. M.; Navarro Tobar, A.; Perez Dengra, C.; Perez-Calero Yzquierdo, A.; Puerta Pelayo, J.; Redondo, I.; Redondo Ferrero, D. D.; Romero, L.; Sanchez Navas, S.; Urda Gomez, L.; Vazquez Escobar, J.; Willmott, C.; de Troconiz, J. F.; Alvarez Gonzalez, B.; Cuevas, J.; Fernandez Menendez, J.; Folgueras, S.; Gonzalez Caballero, I.; Gonzalez Fernandez, J. R.; Palencia Cortezon, E.; Ramon Alvarez, C.; Rodriguez Bouza, V.; Soto Rodriguez, A.; Trapote, A.; Vico Villalba, C.; Vischia, P.; Bhowmik, S.; Blanco Fernandez, S.; Brochero Cifuentes, J. A.; Cabrillo, I. J.; Calderon, A.; Duarte Campderros, J.; Fernandez, M.; Gomez, G.; Lasaosa Garcia, C.; Martinez Rivero, C.; Ruiz del Arbol, P. Martinez; Matorras, F.; Matorras Cuevas, P.; Navarrete Ramos, E.; Piedra Gomez, J.; Scodellaro, L.; Vila, I.; Vizan Garcia, J. M.; Jayananda, M. K.; Kailasapathy, B.; Sonnadara, D. U. J.; Wickramarathna, D. D. C.; Dharmaratna, W. G. D.; Liyanage, K.; Perera, N.; Wickramage, N.; Abbaneo, D.; Amendola, C.; Auffray, E.; Auzinger, G.; Baechler, J.; Barney, D.; Martinez, A. Bermudez; Bianco, M.; Bilin, B.; Bin Anuar, A. A.; Bocci, A.; Botta, C.; Brondolin, E.; Caillol, C.; Cerminara, G.; Chernyavskaya, N.; d'Enterria, D.; Dabrowski, A.; David, A.; De Roeck, A.; Defranchis, M. M.; Deile, M.; Dobson, M.; Forthomme, L.; Franzoni, G.; Funk, W.; Giani, S.; Gigi, D.; Gill, K.; Glege, F.; Gouskos, L.; Haranko, M.; Hegeman, J.; Huber, B.; Innocente, V.; James, T.; Janot, P.; Kaluzinska, O.; Laurila, S.; Lecoq, P.; Leutgeb, E.; Lourenco, C.; Maier, B.; Malgeri, L.; Mannelli, M.; Marini, A. C.; Matthewman, M.; Meijers, F.; Mersi, S.; Meschi, E.; Milosevic, V.; Monti, F.; Moortgat, F.; Mulders, M.; Neutelings, I.; Orfanelli, S.; Pantaleo, F.; Petrucciani, G.; Pfeiffer, A.; Pierini, M.; Piparo, D.; Qu, H.; Rabady, D.; Gutierrez, G. Reales; Rovere, M.; Sakulin, H.; Scarfi, S.; Schwick, C.; Selvaggi, M.; Shchelina, K.; Silva, P.; Sphicas, P.; Leiton, A. G. Stahl; Steen, A.; Summers, S.; Treille, D.; Tropea, P.; Tsirou, A.; Walter, D.; Wanczyk, J.; Wuchterl, S.; Zehetner, P.; Zejdl, P.; Zeuner, W. D.; Bevilacqua, T.; Caminada, L.; Ebrahimi, A.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Lange, C.; Missiroli, M.; Noehte, L.; Rohe, T.; Aarrestad, T. K.; Androsov, K.; Backhaus, M.; Calandri, A.; Cazzaniga, C.; Datta, K.; De Cosa, A.; Dissertori, G.; Dittmar, M.; Donega, M.; Eble, F.; Galli, M.; Gedia, K.; Glessgen, F.; Grab, C.; Hits, D.; Lustermann, W.; Lyon, A. -M.; Manzoni, R. A.; Marchegiani, M.; Marchese, L.; Perez, C. Martin; Mascellani, A.; Nessi-Tedaldi, F.; Pauss, F.; Perovic, V.; Pigazzini, S.; Reissel, C.; Reitenspiess, T.; Ristic, B.; Riti, F.; Seidita, R.; Steggemann, J.; Valsecchi, D.; Wallny, R.; Amsler, C.; Bartschi, P.; Brzhechko, D.; Canelli, M. F.; Cormier, K.; Heikkila, J. K.; Huwiler, M.; Jin, W.; Jofrehei, A.; Kilminster, B.; Leontsinis, S.; Liechti, S. P.; Macchiolo, A.; Meiring, P.; Molinatti, U.; Reimers, A.; Robmann, P.; Cruz, S. Sanchez; Senger, M.; Stager, F.; Takahashi, Y.; Tramontano, R.; Adloff, C.; Bhowmik, D.; Kuo, C. M.; Lin, W.; Rout, P. K.; Tiwari, P. C.; Yu, S. S.; Ceard, L.; Chao, Y.; Chen, K. F.; Chen, P. S.; Chen, Z. G.; De Iorio, A.; Hou, W. -S.; Hsu, T. H.; Kao, Y. W.; Khurana, R.; Kole, G.; Li, Y. Y.; Lu, R. -S.; Paganis, E.; Su, X. F.; Thomas-Wilsker, J.; Tsai, L. S.; Wu, H. Y.; Yazgan, E.; Asawatangtrakuldee, C.; Srimanobhas, N.; Wachirapusitanand, V.; Agyel, D.; Boran, F.; Demiroglu, Z. S.; Dolek, F.; Dumanoglu, I.; Eskut, E.; Guler, Y.; Guler, E. Gurpinar; Isik, C.; Kara, O.; Topaksu, A. Kayis; Kiminsu, U.; Onengut, G.; Ozdemir, K.; Polatoz, A.; Tali, B.; Tok, U. G.; Turkcapar, S.; Uslan, E.; Zorbakir, I. S.; Yalvac, M.; Akgun, B.; Atakisi, I. O.; Gulmez, E.; Kaya, M.; Kaya, O.; Tekten, S.; Cakir, A.; Cankocak, K.; Komurcu, Y.; Sen, S.; Aydilek, O.; Cerci, S.; Epshteyn, V.; Hacisahinoglu, B.; Hos, I.; Kaynak, B.; Ozkorucuklu, S.; Potok, O.; Sert, H.; Simsek, C.; Zorbilmez, C.; Isildak, B.; Cerci, D. Sunar; Boyaryntsev, A.; Grynyov, B.; Levchuk, L.; Anthony, D.; Brooke, J. J.; Bundock, A.; Bury, F.; Clement, E.; Cussans, D.; Flacher, H.; Glowacki, M.; Goldstein, J.; Heath, H. F.; Kreczko, L.; Paramesvaran, S.; Robertshaw, L.; El Nasr-Storey, S. Seif; Smith, V. J.; Stylianou, N.; Pass, K. Walkingshaw; White, R.; Ball, A. H.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Cockerill, D. J. A.; Cooke, C.; Ellis, K. V.; Harder, K.; Harper, S.; Holmberg, M. -L.; Linacre, J.; Manolopoulos, K.; Newbold, D. M.; Olaiya, E.; Petyt, D.; Reis, T.; Sahasransu, A. R.; Salvi, G.; Schuh, T.; Shepherd-Themistocleous, C. H.; Tomalin, I. R.; Williams, T.; Bainbridge, R.; Bloch, P.; Brown, C. E.; Buchmuller, O.; Cacchio, V.; Montoya, C. A. Carrillo; Chahal, G. S.; Colling, D.; Dancu, J. S.; Das, I.; Dauncey, P.; Davies, G.; Davies, J.; Della Negra, M.; Fayer, S.; Fedi, G.; Hall, G.; Hassanshahi, M. H.; Howard, A.; Iles, G.; Knight, M.; Langford, J.; Holgado, J. Leon; Lyons, L.; Magnan, A. -M.; Malik, S.; Mieskolainen, M.; Nash, J.; Pesaresi, M.; Radburn-Smith, B. C.; Richards, A.; Rose, A.; Savva, K.; Seez, C.; Shukla, R.; Tapper, A.; Uchida, K.; Uttley, G. P.; Vage, L. H.; Virdee, T.; Vojinovic, M.; Wardle, N.; Winterbottom, D.; Coldham, K.; Cole, J. E.; Khan, A.; Kyberd, P.; Reid, I. D.; Abdullin, S.; Brinkerhoff, A.; Caraway, B.; Collins, E.; Dittmann, J.; Hatakeyama, K.; Hiltbrand, J.; McMaster, B.; Saunders, M.; Sawant, S.; Sutantawibul, C.; Wilson, J.; Bartek, R.; Dominguez, A.; Escamilla, C. Huerta; Simsek, A. E.; Uniyal, R.; Hernandez, A. M. Vargas; Bam, B.; Chudasama, R.; Cooper, S. I.; Gleyzer, S. V.; Perez, C. U.; Rumerio, P.; Usai, E.; Yi, R.; Akpinar, A.; Arcaro, D.; Cosby, C.; Demiragli, Z.; Erice, C.; Fangmeier, C.; Madrazo, C. Fernandez; Fontanesi, E.; Gastler, D.; Golf, F.; Jeon, S.; Reed, I.; Rohlf, J.; Salyer, K.; Sperka, D.; Spitzbart, D.; Suarez, I.; Tsatsos, A.; Yuan, S.; Zecchinelli, A. G.; Benelli, G.; Coubez, X.; Cutts, D.; Hadley, M.; Heintz, U.; Hogan, J. M.; Kwon, T.; Landsberg, G.; Lau, K. T.; Li, D.; Luo, J.; Narain, M.; Pervan, N.; Sagir, S.; Simpson, F.; Stamenkovic, M.; Yan, X.; Zhang, W.; Abbott, S.; Bonilla, J.; Brainerd, C.; Breedon, R.; Cai, H.; Sanchez, M. Calderon De La Barca; Chertok, M.; Citron, M.; Conway, J.; Cox, P. T.; Erbacher, R.; Jensen, F.; Kukral, O.; Mocellin, G.; Mulhearn, M.; Pellett, D.; Wei, W.; Yao, Y.; Zhang, F.; Bachtis, M.; Cousins, R.; Datta, A.; Avila, G. Flores; Hauser, J.; Ignatenko, M.; Iqbal, M. A.; Lam, T.; Manca, E.; Del Prado, A. Nunez; Saltzberg, D.; Valuev, V.; Clare, R.; Gary, J. W.; Gordon, M.; Hanson, G.; Si, W.; Wimpenny, S.; Branson, J. G.; Cittolin, S.; Cooperstein, S.; Diaz, D.; Duarte, J.; Giannini, L.; Guiang, J.; Kansal, R.; Krutelyov, V.; Lee, R.; Letts, J.; Masciovecchio, M.; Mokhtar, F.; Mukherjee, S.; Pieri, M.; Quinnan, M.; Narayanan, B. V. Sathia; Sharma, V.; Tadel, M.; Vourliotis, E.; Wurthwein, F.; Xiang, Y.; Yagil, A.; Barzdukas, A.; Brennan, L.; Campagnari, C.; Incandela, J.; Li, A. J.; Masterson, P.; Mei, H.; Richman, J.; Sarica, U.; Schmitz, R.; Setti, F.; Sheplock, J.; Stuart, D.; Vami, T. A.; Wang, S.; Bornheim, A.; Cerri, O.; Latorre, A.; Mao, J.; Newman, H. B.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhu, R. Y.; Alison, J.; An, S.; Andrews, M. B.; Bryant, P.; Cremonesi, M.; Dutta, V.; Ferguson, T.; Harilal, A.; Liu, C.; Mudholkar, T.; Murthy, S.; Palit, P.; Paulini, M.; Roberts, A.; Sanchez, A.; Terrill, W.; Cumalat, J. P.; Ford, W. T.; Hart, A.; Hassani, A.; Karathanasis, G.; MacDonald, E.; Manganelli, N.; Perloff, A.; Savard, C.; Schonbeck, N.; Stenson, K.; Ulmer, K. A.; Wagner, S. R.; Zipper, N.; Alexander, J.; Bright-Thonney, S.; Chen, X.; Cranshaw, D. J.; Fan, J.; Fan, X.; Gadkari, D.; Hogan, S.; Kotamnives, P.; Monroy, J.; Oshiro, M.; Patterson, J. R.; Reichert, J.; Reid, M.; Ryd, A.; Thom, J.; Wittich, P.; Zou, R.; Albrow, M.; Alyari, M.; Amram, O.; Apollinari, G.; Apresyan, A.; Bauerdick, L. A. T.; Berry, D.; Berryhill, J.; Bhat, P. C.; Burkett, K.; Butler, J. N.; Canepa, A.; Cerati, G. B.; Cheung, H. W. K.; Chlebana, F.; Cummings, G.; Dickinson, J.; Dutta, I.; Elvira, V. D.; Feng, Y.; Freeman, J.; Gandrakota, A.; Gecse, Z.; Gray, L.; Green, D.; Grummer, A.; Grunendahl, S.; Guerrero, D.; Gutsche, O.; Harris, R. M.; Heller, R.; Herwig, T. C.; Hirschauer, J.; Horyn, L.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klijnsma, T.; Klima, B.; Kwok, K. H. M.; Lammel, S.; Lincoln, D.; Lipton, R.; Liu, T.; Madrid, C.; Maeshima, K.; Mantilla, C.; Mason, D.; McBride, P.; Merkel, P.; Mrenna, S.; Nahn, S.; Ngadiuba, J.; Noonan, D.; Papadimitriou, V.; Pastika, N.; Pedro, K.; Pena, C.; Ravera, F.; Hall, A. Reinsvold; Ristori, L.; Sexton-Kennedy, E.; Smith, N.; Soha, A.; Spiegel, L.; Stoynev, S.; Strait, J.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Whitbeck, A.; Zoi, I.; Aruta, C.; Avery, P.; Bourilkov, D.; Cadamuro, L.; Chang, P.; Cherepanov, V.; Field, R. D.; Koenig, E.; Kolosova, M.; Konigsberg, J.; Korytov, A.; Matchev, K.; Menendez, N.; Mitselmakher, G.; Mohrman, K.; Madhu, A. Muthirakalayil; Rawal, N.; Rosenzweig, D.; Rosenzweig, S.; Adams, T.; Al Kadhim, A.; Askew, A.; Bower, S.; Habibullah, R.; Hagopian, V.; Hashmi, R.; Kim, R. S.; Kolberg, T.; Martinez, G.; Prosper, H.; Prova, P. R.; Wulansatiti, M.; Yohay, R.; Zhang, J.; Alsufyani, B.; Baarmand, M. M.; Butalla, S.; Elkafrawy, T.; Hohlmann, M.; Verma, R. Kumar; Rahmani, M.; Yanes, E.; Adams, M. R.; Baty, A.; Bennett, C.; Cavanaugh, R.; Franco, R. Escobar; Evdokimov, O.; Gerber, C. E.; Hofman, D. J.; Lee, J. H.; Lemos, D. S.; Merrit, A. H.; Mills, C.; Nanda, S.; Oh, G.; Ozek, B.; Pilipovic, D.; Pradhan, R.; Roy, T.; Rudrabhatla, S.; Tonjes, M. B.; Varelas, N.; Ye, Z.; Alhusseini, M.; Blend, D.; Dilsiz, K.; Emediato, L.; Karaman, G.; Koseyan, O. K.; Merlo, J. -P.; Mestvirishvili, A.; Nachtman, J.; Neogi, O.; Ogul, H.; Onel, Y.; Penzo, A.; Snyder, C.; Tiras, E.; Blumenfeld, B.; Corcodilos, L.; Davis, J.; Gritsan, A. V.; Kang, L.; Kyriacou, S.; Maksimovic, P.; Roguljic, M.; Roskes, J.; Sekhar, S.; Swartz, M.; Abreu, A.; Alcerro, L. F. Alcerro; Anguiano, J.; Baringer, P.; Bean, A.; Flowers, Z.; Grove, D.; King, J.; Krintiras, G.; Lazarovits, M.; Le Mahieu, C.; Marquez, J.; Minafra, N.; Murray, M.; Nickel, M.; Pitt, M.; Popescu, S.; Rogan, C.; Royon, C.; Salvatico, R.; Sanders, S.; Smith, C.; Wilson, G.; Allmond, B.; Ivanov, A.; Kaadze, K.; Kalogeropoulos, A.; Maravin, Y.; Natoli, J.; Roy, D.; Sorrentino, G.; Rebassoo, F.; Wright, D.; Baden, A.; Belloni, A.; Chen, Y. M.; Eno, S. C.; Hadley, N. J.; Jabeen, S.; Kellogg, R. G.; Koeth, T.; Lai, Y.; Lascio, S.; Mignerey, A. C.; Nabili, S.; Palmer, C.; Papageorgakis, C.; Paranjpe, M. M.; Wang, L.; Bendavid, J.; Cali, I. A.; D'Alfonso, M.; Eysermans, J.; Freer, C.; Gomez-Ceballos, G.; Goncharov, M.; Grosso, G.; Harris, P.; Hoang, D.; Kovalskyi, D.; Krupa, J.; Lavezzo, L.; Lee, Y. -J.; Long, K.; Novak, A.; Paus, C.; Rankin, D.; Roland, C.; Roland, G.; Rothman, S.; Stephans, G. S. F.; Wyslouch, B.; Yang, T. J.; Crossman, B.; Joshi, B. M.; Kapsiak, C.; Krohn, M.; Mahon, D.; Mans, J.; Marzocchi, B.; Pandey, S.; Revering, M.; Rusack, R.; Saradhy, R.; Schroeder, N.; Strobbe, N.; Wadud, M. A.; Cremaldi, L. M.; Bloom, K.; Claes, D. R.; Haza, G.; Hossain, J.; Joo, C.; Kravchenko, I.; Siado, J. E.; Tabb, W.; Vagnerini, A.; Wightman, A.; Yan, F.; Yu, D.; Bandyopadhyay, H.; Hay, L.; Iashvili, I.; Kharchilava, A.; Morris, M.; Nguyen, D.; Rappoccio, S.; Sfar, H. Rejeb; Williams, A.; Alverson, G.; Barberis, E.; Dervan, J.; Haddad, Y.; Han, Y.; Krishna, A.; Li, J.; Lu, M.; Madigan, G.; Mccarthy, R.; Morse, D. 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Riga Tech Univ, Riga, Latvia; Univ Kebangsaan Malaysia, Fac Sci & Technol, Dept Appl Phys, Bangi, Malaysia; Consejo Nacl Ciencia & Technol, Mexico City, DF, Mexico; Eastern Univ, Trincomalee Campus, Nilaveli, Sri Lanka; Saegis Campus, Nugegoda, Sri Lanka; Natl & Kapodistrian Univ Athens, Athens, Greece; Ecole Polytech Fed Lausanne, Lausanne, Switzerland; Univ Zurich, Zurich, Switzerland; Stefan Meyer Inst Subat Phys, Vienna, Austria; CNRS, IN2P3, Lab Annecy Le Vieux Phys Particules, Annecy Le Vieux, France; Near East Univ, Res Ctr Expt Hlth Sci, Mersin, Turkiye; Konya Tech Univ, Konya, Turkiye; Izmir Bakircay Univ, Izmir, Turkiye; Adiyaman Univ, Adiyaman, Turkiye; Bozok Univ Rektorlugu, Yozgat, Turkiye; Marmara Univ, Istanbul, Turkiye; Milli Savunma Univ, Istanbul, Turkiye; Kafkas Univ, Kars, Turkiye; Istanbul Okan Univ, Istanbul, Turkiye; Hacettepe Univ, Ankara, Turkiye; Istanbul Univ Cerrahpasa, Fac Engn, Istanbul, Turkiye; Yildiz Tech Univ, Istanbul, Turkiye; Vrije Univ Brussel, Brussels, Belgium; Univ Southampton, Sch Phys & Astron, Southampton, Hants, England; Univ Bristol, Bristol, Avon, England; IPPP Durham Univ, Durham, England; Monash Univ, Fac Sci, Clayton, Vic, Australia; Univ Torino, Turin, Italy; Bethel Univ, St Paul, MN USA; Karamanoglu Mehmetbey Univ, Karaman, Turkiye; CALTECH, Pasadena, CA 91125 USA; US Naval Acad, Annapolis, MD 21402 USA; Bingol Univ, Bingol, Turkiye; Georgian Tech Univ, Tbilisi, Georgia; Sinop Univ, Sinop, Turkiye; Erciyes Univ, Kayseri, Turkiye; Horia Hulubei Natl Inst Phys & Nucl Engn IFIN HH, Bucharest, Romania; Texas A&M Univ Qatar, Doha, Qatar; Kyungpook Natl Univ, Daegu, South Korea; Uzbek Acad Sci, Inst Nucl Phys, Tashkent, Uzbekistan; Northeastern Univ, Boston, MA 02115 USA | Sunar Cerci, Deniz/AHE-1706-2022; Cadamuro, Luca/AAO-8637-2020; Dremin, Igor/K-8053-2015; Singh, J B/IXD-2130-2023; Pinna Angioni, Gian Luca/AAZ-6834-2021; Roy Chowdhury, Suvankar/IXN-7230-2023; Gil Da Silveira, Gustavo/N-7279-2014; Aruta, Caterina/NRX-9970-2025; Fiorina, Davide/HKE-5979-2023; Shopova, Mariana/HKW-0149-2023; HAJAHMAD (Wael HAJ AHMAD), Vael/E-6738-2016; de Souza Sandro, Fonseca/ABB-8505-2020; Mignerey, Alice/D-6623-2011; Padula, Sandra/AAE-4304-2020; Mercadante, Pedro/K-1918-2012; Terkulov, Adel/M-8581-2015; Dewanjee, Ram Krishna/AFE-3468-2022; Sonnadara, Upul/E-6359-2010; Malvezzi, Sandra/B-8524-2009; Anampa, Kenyi/GPX-8479-2022; Dallavalle, Gaetano Marco/AFW-4654-2022; Mundim, Luiz/A-1291-2012; Pinheiro, Joao/LMN-5088-2024; Benaglia, Andrea/AGF-5495-2022; Chistov, Ruslan/B-4893-2014; Manca, Elisabetta/NRA-8419-2025; Ambrozas, Marijus/F-5551-2018; Presilla, Matteo/MGW-3532-2025; Castilla-Valdez, Heriberto/F-8906-2019; Focardi, Ettore/E-7376-2012; Wimpenny, Stephen/K-8848-2013; Gregores, Eduardo/F-8702-2012; ciocci, maria/I-2153-2015; Escobar, Juan/JLM-3900-2023; Malagalage, Kithsiri/F-7629-2018; Gaile, Anastasija/KLE-1958-2024; Rout, Prasanna/N-8012-2019; Kodolova, Olga/IQV-0056-2023; Gleyzer, Sergei/AAE-6726-2020; Gupta, Rajat/GVS-7964-2022; Fernandez Menendez, Javier/B-6550-2014; Gavrilov, Gennadii/GRO-6222-2022; MAESTRE, JUAN/I-5763-2015; Josa, Isabel/K-5184-2014; Duarte-Campderrós, Jordi/F-5025-2018; Bedoya, Cristina/K-8066-2014; Watson, Ian/IAM-9344-2023; Vai, Ilaria/AAT-5836-2020; Steggemann, Jan/AAL-5700-2020; Cunqueiro Mendez, Leticia/HJP-0371-2023; Ferencek, Dinko/G-6411-2015; Demiroglu, Zuhal Seyma/A-5168-2016; Safronov, Grigory/F-8494-2017; Aarrestad, Thea/GLV-3031-2022; Canelli, Florencia/O-9693-2016; Tuo, Shengquan/ABA-9032-2021; Dimova, Tatyana/AAQ-9303-2021; Mejia Guisao, Jhovanny/ABG-3627-2021; Mora Herrera, Clemencia/AAD-6466-2021; Navarro-Tobar, Álvaro/K-7864-2014; Elkafrawy, Tamer/HPF-5873-2023; Verdini, Piero/J-2839-2012; Behera, Prafulla/AAK-8686-2020; Tornago, Marta/NGS-5785-2025; KAYİS TOPAKSU, Aysel/B-8910-2018; Akgun, Bora/AAM-8311-2021; Delgado Peris, Antonio/AAA-5165-2019; Ulrich, Ralf/Q-3882-2019; Ruhlmann-Kleider, Vanina/AGJ-4460-2022; Cardini, Andrea/KUF-0984-2024; Dewanjee, Dr. Ram Krishna/AFE-3468-2022; Tytgat, Michael/F-3732-2018; Montanari, Alessandro/J-2420-2012; Baskakov, Alexey/O-4521-2017; Quijada, Javier/AAS-4234-2021; Moon, Chang-Seong/J-3619-2014; Teles, Patricia/ABF-9723-2021; Ciangottini, Diego/HJH-5914-2023; Eskut, Eda/B-8905-2018; Abdallah, Hassan/AEE-4715-2022; Hoorani, Hafeez/D-1791-2013; Ogul, Hasan/S-7951-2016; Caballero, Isidro/E-7354-2010; Obertino, Maria/ABH-1662-2020; Gonzalez, Arely/I-1034-2015; Fouz, Maria Cruz/AAF-1105-2019; Tuominen, Eija/A-5288-2017; Mora Herrera, Maria Clemencia/AAD-6466-2021; D'Alessandro, Raffaello/P-4138-2019; Rivero, Celso/V-6916-2017; Najafabadi, Mojtaba/AAF-7564-2019; Mishra, Trilochan/A-7947-2010; Puerta Pelayo, Jesus/L-1632-2014; Veckalns, Viesturs/AAZ-3105-2020; Vala, Martin/HZL-1003-2023; Sznajder, Andre/L-1621-2016; Simone, Federica/HDM-3686-2022; Mota Amarilo, Kevin/JCE-6631-2023; Tomei, Thiago/E-7091-2012; liu, xiao/HMD-7454-2023; Janssen, Tomas/GNO-9403-2022; Di Florio, Adriano/ABA-3631-2020; Yazgan, Efe/C-4521-2014; Heredia De La Cruz, Ivan/L-2610-2018; Wulz, Claudia-Elisabeth/H-5657-2011; Gokbulut, Gul/G-2141-2018; SIMSEK, Ali Eren/AFO-3050-2022; Masciovecchio, Mario/IXD-8018-2023; Sert, H/ABA-5645-2020; Gozalez-Lopez, Oscar/AAH-3533-2019 | PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS | PHYS REP | 0370-1573 | 1873-6270 | 1115 | SCIE | PHYSICS, MULTIDISCIPLINARY | 2024 | 29.5 | 2.2 | 1 | CMS; Heavy ion physics; QGP; Overview | CHARGED-PARTICLE MULTIPLICITY; NUCLEUS-NUCLEUS COLLISIONS; HEAVY-ION COLLISIONS; QUARK-GLUON PLASMA; BOSE-EINSTEIN CORRELATIONS; DEEP-INELASTIC-SCATTERING; PHOTON-PHOTON COLLISIONS; PLUS PB COLLISIONS; PARTON ENERGY-LOSS; PERIPHERAL COLLISIONS | English | 2025 | 2025-04-17 | 10.1016/j.physrep.2024.11.007 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | Sodium cation exchanged zeolites for direct air capture of CO2 | Direct air capture technology requires investigating materials that can capture carbon dioxide inexpensively and efficiently, considering their performance under real atmospheric conditions. This study systematically investigated the CO2 adsorption-desorption performance of the representative zeolites (ZSM-5, Beta, Mordenite and Y) in H- and Na-forms using various analytical methods, including in-situ Diffuse Reflectance Infrared Fourier Transform spectroscopy. Compared to the corresponding H-zeolites, the enhancement of CO2 adsorption capacity by Na+ ions was observed for all the structure-type zeolite adsorbents. The Na-ZSM-5 showed excellent performance in the direct air capture of CO2 (DAC) due to its relatively smaller pore size and stronger acid-basic properties. The effective adsorption capacity of Na-ZSM-5 was pronounced at lower Si/Al ratios, making it the most efficient low-concentration CO2 adsorbent. The low silica Na-ZSM-5 exhibited a durable adsorptiondesorption capacity after multiple cycles, indicating its practical reusability. When applied to real atmospheric air conditions, this low silica Na-ZSM-5 effectively adsorbed CO2 in the presence of oxygen and moisture, emphasizing its potential for a direct air capture adsorbent. This study provides insights into the properties of zeolites for CO2 capture from air, highlighting their potential as effective DAC sorbents that can be produced on a large scale. | Kim, Do Yeong; Bae, Wo Bin; Min, Haehyun; Ryu, Kyeong-Hun; Kweon, Sungjoon; Tran, Linh Mai; Kim, Young Jin; Park, Min Bum; Kang, Sung Bong | Gwangju Inst Sci & Technol, Sch Environm & Energy Engn, Gwangju 61005, South Korea; Incheon Natl Univ, Dept Energy & Chem Engn, Incheon 22012, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Gwangju Inst Sci & Technol, Res Ctr Innovat Energy & Carbon Optimized Synth Ch, Gwangju 61005, South Korea | 57481464200; 57218296461; 57367334300; 59424163300; 57201686056; 58939563900; 59054565400; 34873080400; 59969495200 | mbpark@inu.ac.kr; sbkang@gist.ac.kr; | APPLIED SURFACE SCIENCE ADVANCES | APPL SURF SCI ADV | 2666-5239 | 25 | ESCI | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, COATINGS & FILMS;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 8.7 | 2.2 | 3.99 | 2025-05-07 | 2 | 3 | Direct air capture; Zeolite; Na + -exchange; Acid-basic site | CATALYTIC-PROPERTIES; CARBON-DIOXIDE; ADSORPTION; BASICITY; ALKALI; NA; ADSORBENTS; FAUJASITES; ZSM-5; FTIR | Acid-basic site; CO<sub>2</sub>; Direct air capture; Na<sup>+</sup>-exchange; Zeolite | English | 2025 | 2025-01 | 10.1016/j.apsadv.2024.100664 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | A scalable 3D packaging technique for brain organoid arrays toward high-capacity bioprocessors | Neural organoids provide a promising platform for biologically inspired computing due to their complex neural architecture and energy-efficient signal processing. However, the scalability of conventional organoid cultures is limited, restricting synaptic connectivity and functional capacity-significant barriers to developing highperformance bioprocessors. Here, we present a scalable three-dimensional (3D) packaging strategy for neural organoid arrays inspired by semiconductor 3D stacking technology. This approach vertically assembles Matrigelembedded neural organoids within a polydimethylsiloxane (PDMS)-based chamber using a removable acrylic alignment plate, creating a stable multilayer structure while preserving oxygen and nutrient diffusion. Structural analysis confirms robust inter-organoid connectivity, while electrophysiological recordings reveal significantly enhanced neural dynamics in 3D organoid arrays compared to both single organoids and two-dimensional arrays. Furthermore, prolonged culture duration promotes network maturation and increases functional complexity. This 3D stacking strategy provides a simple yet effective method for expanding the physical and functional capacity of organoid-based systems, offering a viable path toward next-generation biocomputing platforms. | Kim, Jeong Hee; Kim, Minseok; Kim, Keun-Tae; Chou, Namsun; Kim, Hong Nam; Cho, Il-Joo; Lee, Ju-Hyun; Shin, Hyogeun | Korea Inst Sci & Technol KIST, Brain Sci Inst, Seoul, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Korea Univ, Coll Med, Dept Biomed Sci, Seoul, South Korea; Korea Brain Res Inst KBRI, Emot Cognit & Behav Res Grp, Daegu, South Korea; Univ Sci & Technol UST, KIST Sch, Div Biomed Sci & Technol, Seoul, South Korea; Yonsei Univ, Sch Mech Engn, Seoul, South Korea; Yonsei Univ, Yonsei KIST Convergence Res Inst, Seoul, South Korea; Korea Univ, Coll Med, Dept Convergence Med, Seoul, South Korea; Korea Univ, Coll Med, Inst Human Genet, Seoul, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu, South Korea | 59951098500; 59073001500; 57212018427; 43061070600; 35205791200; 59951098600; 59950950300; 56591066700 | juhyun.lee@kist.re.kr; hyogeunshin@knu.ac.kr; | BIOSENSORS & BIOELECTRONICS | BIOSENS BIOELECTRON | 0956-5663 | 1873-4235 | 287 | SCIE | BIOPHYSICS;CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;NANOSCIENCE & NANOTECHNOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2024 | 10.5 | 2.3 | N/A | 0 | 0 | Brain organoid; 3D packaging technique; Organoid-based bioprocessor; Neural signal recording; Functional connectivity; Complex neural network | CEREBRAL ORGANOIDS; MODEL | 3D packaging technique; Brain organoid; Complex neural network; Functional connectivity; Neural signal recording; Organoid-based bioprocessor | Biomedical signal processing; Biomimetics; Brain; Chip scale packages; Electrophysiology; Multilayer neural networks; Packaging; Three dimensional integrated circuits; caspase 3; dimeticone; fibroblast growth factor; Bioprocessors; Brain organoid; Complex neural networks; Functional connectivity; Neural signal recording; Organoid-based bioprocessor; Organoids; Packaging techniques; Three dimensional packaging; Three-dimensional packaging technique; 3d packaging technique; Article; cell death; cell differentiation; cell viability; central nervous system; cerebral organoid; connectome; dynamics; extracellular matrix; human; human cell; human embryonic stem cell; methodology; organoid; room temperature; scanning electron microscopy; WA09 human embryonic stem cell; Complex networks | English | 2025 | 2025-11-01 | 10.1016/j.bios.2025.117703 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Acid sphingomyelinase activity suggests a new antipsychotic pharmaco-treatment strategy for schizophrenia | Schizophrenia is a chronic and severe mental disorder. It is currently treated with antipsychotic drugs (APD). However, APD's work only in a limited number of patients and may have cognition impairing side effects. A growing body of evidence points out the potential involvement of abnormal sphingolipid metabolism in the pathophysiology of schizophrenia. Here, an analysis of human gene polymorphisms and brain gene expression in schizophrenia patients identified an association of SMPD1 and SMPD3 genes coding for acid- (ASM) and neutral sphingomyelinase-2 (NSM). In a rat model of psychosis using amphetamine hypersensitization, we found a locally restricted increase of ASM activity in the prefrontal cortex (PFC). Short-term haloperidol (HAL) treatment reversed behavioral symptoms and the ASM activity. A sphingolipidomic analysis confirmed an altered ceramide metabolism in the PFC during psychosis. Targeting enhanced ASM activity in a psychotic-like state with the ASM inhibitor KARI201 reversed psychotic like behavior and associated changes in the sphingolipidome. While effective HAL treatment led to locomotor decline and cognitive impairments, KARI201 did not. An RNA sequencing analysis of the PFC suggested a dysregulation of numerous schizophrenia related genes including Olig1, Fgfr1, Gpr17, Gna12, Abca2, Sox1, Dpm2, and Rab2a in the rat model of psychosis. HAL and KARI201 antipsychotic effects were associated with targeting expression of other schizophrenia associated genes like Col6a3, Slc22a8, and Bmal1, or Nr2f6a, respectively, but none affecting expression of sphingolipid regulating genes. Our data provide new insight into a potentially pathogenic mechanism of schizophrenia and suggest a new pharmaco-treatment strategy with reduced side effects. | Chestnykh, Daria; Muehle, Christiane; Schumacher, Fabian; Kalinichenko, Liubov S.; Loeber, Stefan; Gmeiner, Peter; Alzheimer, Christian; von Hoersten, Stephan; Kleuser, Burkhard; Uebe, Steffen; Ekici, Arif B.; Gulbins, Erich; Kornhuber, Johannes; Jin, Hee Kyung; Bae, Jae-sung; Lourdusamy, Anbarasu; Mueller, Christian P. | Friedrich Alexander Univ Erlangen Nuremberg, Univ Clin, Dept Psychiat & Psychotherapy, Erlangen, Germany; FREIE UNIV BERLIN, INST PHARM, BERLIN, GERMANY; Friedrich Alexander Univ Erlangen Nurnberg, Dept Chem & Pharm Med Chem, Nikolaus Fiebiger Str 10, D-91058 Erlangen, Germany; Friedrich Alexander Univ Erlangen Nurnberg, FAUNeW Res Ctr New Bioact Cpds, Nikolaus Fiebiger Str 10, D-91058 Erlangen, Germany; Friedrich Alexander Univ Erlangen Nuremberg, Inst Physiol & Pathophysiol, D-91054 Erlangen, Germany; Friedrich Alexander Univ Erlangen Nuremberg, Preclin Expt Ctr, Dept Expt Therapy, Erlangen, Germany; Friedrich Alexander Univ Erlangen Nuremberg, Inst Human Genet, Erlangen, Germany; Univ Duisburg Essen, Dept Mol Biol, D-45147 Essen, Germany; Univ Cincinnati, Coll Med, Dept Surg, 231 Albert Sabin Way, Cincinnati, OH 45267, USA; Kyungpook Natl Univ, KNU Alzheimers Dis Res Inst, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Lab Anim Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu 41944, South Korea; Univ Nottingham, Sch Med, Acad Unit Translat Med Sci, Nottingham NG7 2UH, England; Heidelberg Univ, Cent Inst Mental Hlth, Med Fac Mannheim, Dept Addict Behav & Addict Med, Mannheim, Germany | Ekici, Arif/C-3971-2013; von Hörsten, Stephan/G-9005-2015; Lourdusamy, Anbarasu/G-3387-2011; Bae, Jae-sung/AAM-8663-2021; von Horsten, Stephan/G-9005-2015; Uebe, Steffen/JXX-3960-2024; Schumacher, Fabian/ABC-1750-2020; Mühle, Christiane/AAE-7043-2019 | 57221721006; 7006133564; 47461634100; 36168276300; 6602508671; 7006304590; 15030878900; 7003540594; 7004519246; 6507425429; 57222581591; 57189933022; 7007179429; 58950699500; 35209510400; 16302062500; 7404109791 | Christian.Mueller@uk-erlangen.de; | MOLECULAR PSYCHIATRY | MOL PSYCHIATR | 1359-4184 | 1476-5578 | 30 | 7 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;NEUROSCIENCES;PSYCHIATRY | 2024 | 10.1 | 2.3 | 4.48 | 2025-05-07 | 1 | 1 | CHRONIC HALOPERIDOL; OBJECT RECOGNITION; BIPOLAR DISORDER; CERAMIDE SYSTEM; ANIMAL-MODELS; IN-VIVO; DOPAMINE; RISPERIDONE; DISRUPTION; METABOLISM | amphetamine; carprofen; ceramide; ghrelin receptor; haloperidol; KARI 201; ketamine; lidocaine; neuroleptic agent; sphingomyelin phosphodiesterase; unclassified drug; xylazine; Alzheimer disease; anaphylaxis; animal experiment; animal model; animal tissue; anxiety; Article; controlled study; DNA polymorphism; drug dose escalation; enzyme activity; experimental behavioral test; gene expression; genetic analysis; genome-wide association study; hippocampus; human; lipidomics; liquid chromatography-mass spectrometry; locomotion; male; nonhuman; novel object recognition test; open field test; phenotype; piezoelectricity; prefrontal cortex; psychosis; rat; RNA sequencing; schizophrenia; sensory gating; sex difference; single nucleotide polymorphism; skin incision; SMPD1 gene; SMPD3 gene; sphingolipid metabolism; thin layer chromatography; upregulation | English | 2025 | 2025-07 | 10.1038/s41380-025-02893-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Evaporative cooling for low-cost monitoring of flow of cerebrospinal fluid through shunts in patients with hydrocephalus | Hydrocephalus, a neurological disorder caused by an abnormal accumulation of cerebrospinal fluid (CSF) in the brain, manifests in symptoms such as headaches, blurred vision, and balance issues. While ventriculoperitoneal shunting is a common treatment, it has high failure rates, especially in pediatric patients. Recent progress in continuous, non-invasive monitoring using skin-mounted sensors based on anemometric techniques and transient plane source methods offer significant promise. Here, we introduce an advanced device of this general type, configured for ultralow power operation and cost-effective construction. The innovation involves replacing heating elements with passive cooling mechanisms driven by water evaporation, thereby reducing the need for high-capacity battery power. Localized cooling at the shunt position (Delta T-skin similar to 6 degrees C) enables flow measurements by creating differential temperature changes in upstream and downstream regions. Quantitative models of thermal transport and systematic experimental studies enable optimized design choices. A compact device with Bluetooth Low Energy (BLE) capabilities and a small battery allows both intermittent evaluations and continuous monitoring. Additional measurements confirm capabilities in accurate flow measurements using passive, non-electronic skin patches, where readout occurs based on colorimetric evaluations of thermochromic liquid crystal (TLC) arrays by digital image analysis. These results provide versatile, cost-effective, and accessible shunt monitoring options suitable for use even in the most resource-constrained regions of lower- and middle-income countries. | Park, Minsu; Li, Shupeng; Song, Kyeong Min; Kwon, Kyeongha; Yun, Jung-Ho; Avila, Raudel; Webb, R. Chad; Arafa, Hany M.; Cho, Soongwon; Lee, Geumbee; Correira, Chase; Kim, Bosung; Kim, Yu Bin; Ha, Hyoun Ji; Maeng, Woo-Youl; Yoo, Jae-Young; Jeong, Hyoyoung; Ryu, Hanjun; Won, Sang Min; Jung, Yei Hwan; Park, Yoonseok; Kang, Seong Jun; Huang, Yonggang; Rogers, John A. | Dankook Univ, Dept Polymer Sci & Engn, Yongin 16890, South Korea; Northwestern Univ, Dept Mech Engn, Evanston, IL 60208 USA; Northwestern Univ, Querrey Simpson Inst Bioelect, Evanston, IL 60208 USA; Korea Adv Inst Sci & Technol, Sch Elect Engn, Daejeon 34141, South Korea; Dankook Univ Hosp, Trauma Ctr, Dept Neurosurg, Cheonan 31116, South Korea; Rice Univ, Dept Mech Engn, Houston, TX 77005 USA; Rhaeos Inc, Evanston, IL 60201 USA; Kyungpook Natl Univ, Dept Chem Engn, Daegu 41566, South Korea; Kyung Hee Univ, Dept Adv Mat Engn Informat & Elect, Yongin 17104, South Korea; Sungkyunkwan Univ, Dept Semicond Convergence Engn, Suwon 16419, South Korea; Univ Calif Davis, Dept Elect & Comp Engn, Davis, CA 95616 USA; Chung Ang Univ, Dept Adv Mat Engn, Anseong 17546, South Korea; Sungkyunkwan Univ, Dept Elect & Comp Engn, Suwon 16419, South Korea; Hanyang Univ, Dept Elect Engn, Seoul 04763, South Korea; Kyung Hee Univ, Dept Adv Mat Engn Informat & Elect, Integrated Educ Frontier Sci & Technol BK21 Four, 1732 Deogyeong Daero, Yongin 17104, South Korea; Kyung Hee Univ, KHU KIST Dept Converging Sci & Technol, Seoul 02447, South Korea; Northwestern Univ, Dept Mat Sci & Engn, Evanston, IL 60208 USA; Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA; Northwestern Univ, Feinberg Sch Med, Dept Neurol Surg, Chicago, IL 60611 USA | Soongwon, Cho/MEK-8365-2025; Park, Minsu/LEM-2134-2024; Ryu, Hanjun/L-6632-2015; huang, yonggang/O-6236-2019; Jung, Yei/B-9184-2013 | 59253689000; 57205673945; 59682761500; 56109998000; 57225731324; 57125663400; 56289252100; 56470570900; 59307239200; 56300598400; 59681756400; 57219846219; 58880349300; 58028424700; 57190286352; 56683681300; 57195675635; 56594263100; 26423371000; 49561234300; 57189441895; 36175986300; 7501569901; 56755517500 | y-huang@northwestern.edu; jrogers@northwestern.edu; | BIOSENSORS & BIOELECTRONICS | BIOSENS BIOELECTRON | 0956-5663 | 1873-4235 | 278 | SCIE | BIOPHYSICS;CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;NANOSCIENCE & NANOTECHNOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2024 | 10.5 | 2.3 | 0 | 2025-05-07 | 0 | 0 | Bioelectronics; Hydrocephalus; Flow sensor; Passive cooling; Thermochromic liquid crystal | TEMPERATURE; PATENCY | Bioelectronics; Flow sensor; Hydrocephalus; Passive cooling; Thermochromic liquid crystal | Biosensing Techniques; Cerebrospinal Fluid; Cerebrospinal Fluid Shunts; Equipment Design; Humans; Hydrocephalus; Monitoring, Physiologic; Ventriculoperitoneal Shunt; Electrotherapeutics; Evaporative cooling systems; Flowmeters; Noninvasive medical procedures; dimeticone; elastomer; silastic; Bioelectronic; Cost effective; Cost monitoring; Evaporative cooling; Flow-sensors; Hydrocephalus; Low-costs; Neurological disorders; Passive cooling; Thermochromic liquid crystals; adult; Article; blurred vision; calibration; cerebrospinal fluid; child; cooling; encapsulation; evaporation; experimental study; finite element analysis; flow measurement; headache; heating; human; hydrocephalus; image analysis; liquid crystal; motor neuron disease; nanofabrication; neurologic disease; quantitative analysis; temperature; thin layer chromatography; three-dimensional imaging; brain ventricle peritoneum shunt; cerebrospinal fluid; cerebrospinal fluid drainage system; chemistry; devices; equipment design; genetic procedures; physiologic monitoring; procedures; surgery; Cerebrospinal fluid | English | 2025 | 2025-06-15 | 10.1016/j.bios.2025.117349 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | High-precision extracellular-vesicle isolation-analysis integrated platform for rapid cancer diagnosis directly from blood plasma | Cancer-derived small extracellular vesicles (sEVs) in body fluids hold promise as biomarkers for cancer diagnosis. For sEV-based liquid biopsy, isolation of sEVs with a high-purity and cancer-sEV detection with an extremely high sensitivity are essential because body fluids include much higher density of normal-cell-derived sEVs and other biomolecules and bioparticles. Here, we propose an isolation-analysis-integrated cancer-diagnosis platform based on dielectrophoresis(DEP)-ELISA technique which enables a three orders of magnitude higher sensitivity over conventional ELISA method and direct cancer diagnosis from blood plasma with high accuracy. The limit of detection (LOD) for sEVs in human plasma was as low as 10(4) sEVs/mL without a time-consuming and low-yield sEV isolation and purification process. The capability of this platform was validated by monitoring mice with cancer cell inoculation and assessing the effect of cancer-sEV-inhibiting drug. Using the developed sEV-based liquid biopsy, we diagnosed clinical samples from healthy donors (N = 39) and cancer patients (N = 90). The diagnostic accuracy was 94.2%, 98.6%, and 91.3% for breast, colon, and lung cancers, respectively. This integrated sEV isolation and analysis platform could be applied for high-sensitivity biomarker profiling and sEVbased liquid biopsy. | Park, Minsu; Lee, Chan-Hyeong; Noh, Hyowoong; Kang, Geeyoon; Lee, Junyeong; Bae, Ju-Hyun; Moon, Hyeri; Park, Jonghoo; Kong, Seongho; Baek, Moon-Chang; Park, Hongsik | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Exosome Convergence Res Ctr ECRC, Sch Med, Dept Mol Med,CMRI, Daegu 41944, South Korea; Elect & Telecommun Res Inst ETRI, Digital Biomed Res Div, Daejeon 34129, South Korea | 57402583800; 57189904697; 57209882167; 58541881100; 57210867037; 57225046295; 59374044700; 57196408322; 59374044800; 7006013097; 35366976200 | mcbaek@knu.ac.kr; hpark@ee.knu.ac.kr; | BIOSENSORS & BIOELECTRONICS | BIOSENS BIOELECTRON | 0956-5663 | 1873-4235 | 267 | SCIE | BIOPHYSICS;CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;NANOSCIENCE & NANOTECHNOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2024 | 10.5 | 2.3 | 7.87 | 2025-05-07 | 7 | 7 | Small extracellular vesicles Cancer; Diagnosis; Dielectrophoresis; ELISA | EXOSOME ISOLATION; EXPRESSION; PROGRESS; LABEL | Cancer; Diagnosis; Dielectrophoresis; ELISA; Small extracellular vesicles | Animals; Biomarkers, Tumor; Biosensing Techniques; Electrophoresis; Enzyme-Linked Immunosorbent Assay; Extracellular Vesicles; Female; Humans; Limit of Detection; Liquid Biopsy; Mice; Neoplasms; Biomarkers; Biopsy; biological marker; CD63 antigen; low density lipoprotein; tumor marker; Blood plasma; Cancer; Cancer diagnosis; ELISA; Extracellular; High sensitivity; High-precision; Integrated platform; Isolation analysis; Small extracellular vesicle; accuracy; animal cell; animal experiment; animal model; animal tissue; area under the curve; Article; breast cancer; cancer diagnosis; cancer growth; cancer staging; cancer stem cell; chemoluminescence; circulating tumor cell; colon cancer; confocal microscopy; controlled study; diagnostic accuracy; diagnostic test accuracy study; electrolysis; enzyme linked immunosorbent assay; exosome; female; flow cytometry; fluorescence intensity; genotyping; human; immunofluorescence; inoculation; limit of detection; liquid biopsy; lung cancer; major clinical study; male; MDA-MB-231 cell line; microfluidic analysis; mouse; nonhuman; particle size; plasma; polymerase chain reaction; protein analysis; protein purification; receiver operating characteristic; signal processing; tumor cell inoculation; ultracentrifugation; Western blotting; animal; blood; chemistry; diagnosis; electrophoresis; genetic procedures; isolation and purification; neoplasm; procedures; Lung cancer | English | 2025 | 2025-01-01 | 10.1016/j.bios.2024.116863 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Lithium normalizes ASD-related neuronal, synaptic, and behavioral phenotypes in DYRK1A-knockin mice | Dyrk1A deficiency is linked to various neurodevelopmental disorders, including developmental delays, intellectual disability (ID) and autism spectrum disorders (ASD). Haploinsufficiency of Dyrk1a in mice reportedly leads to ASD-related phenotypes. However, the key pathological mechanisms remain unclear and human DYRK1A mutations remain uncharacterized in mice. Here, we generated and studied Dyrk1a-knockin mice carrying a human ASD patient mutation (Ile48LysfsX2; Dyrk1a-I48K mice). These mice display severe microcephaly, social and cognitive deficits, dendritic shrinkage, excitatory synaptic deficits, and altered phospho-proteomic patterns enriched for multiple signaling pathways and synaptic proteins. Early chronic lithium treatment of newborn mutant mice rescues the brain volume, behavior, dendritic, synaptic, and signaling/synapse phospho-proteomic phenotypes at juvenile and adult stages. These results suggest that signaling/synaptic alterations contribute to the phenotypic alterations seen in Dyrk1a-I48K mice, and that early correction of these alterations by lithium treatment has long-lasting effects in preventing juvenile and adult-stage phenotypes. | Roh, Junyeop Daniel; Bae, Mihyun; Kim, Hyosang; Yang, Yeji; Lee, Yeunkeum; Cho, Yisul; Lee, Suho; Li, Yan; Yang, Esther; Jang, Hyunjee; Kim, Hyeonji; Kim, Hyun; Kang, Hyojin; Ellegood, Jacob; Lerch, Jason P.; Bae, Yong Chul; Kim, Jin Young; Kim, Eunjoon | Inst Basic Sci IBS, Ctr Synapt Brain Dysfunct, Daejeon 34141, South Korea; Korea Adv Inst Sci & Technol KAIST, Dept Biol Sci, Daejeon 34141, South Korea; Korea Basic Sci Inst, Digital Omics Res Ctr, Cheongju 28119, South Korea; Korea Inst Drug Safety & Risk Management, Anyang 14051, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Anat & Neurobiol, Daegu 41940, South Korea; Korea Univ, Dept Anat, Coll Med, Seoul 02841, South Korea; Korea Univ, Coll Med, BK21 Grad Program, Biomed Sci, Seoul 02841, South Korea; Bertis Inc, Gwacheon 13840, South Korea; KISTI, Div Natl Supercomp, Daejeon 34141, South Korea; Hosp Sick Children, Mouse Imaging Ctr, Toronto, ON M5T 3H7, Canada; Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Toronto, ON M4G 1R8, Canada; Univ Oxford, Wellcome Ctr Integrat Neuroimaging, Oxford OX3 9DU, England | Kim, Ho/G-2712-2011; Kim, Do Hyun/AAA-2792-2021 | 56973410500; 57205745911; 57192369940; 57826103900; 59464977800; 23979595700; 57202691999; 56799479800; 57194107730; 59465618900; 59464977900; 59866406700; 57203522541; 8327738900; 6602191436; 56377838800; 55952463300; 57203240554 | kime@kaist.ac.kr; | MOLECULAR PSYCHIATRY | MOL PSYCHIATR | 1359-4184 | 1476-5578 | 30 | 6 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;NEUROSCIENCES;PSYCHIATRY | 2024 | 10.1 | 2.3 | 0 | 2025-05-07 | 0 | 0 | DOWN-SYNDROME; INTELLECTUAL DISABILITY; POTENTIAL ROLE; HUMAN HOMOLOG; DYRK1A; BRAIN; GENE; HAPLOINSUFFICIENCY; PLASTICITY; PROTEINS | Animals; Autism Spectrum Disorder; Behavior, Animal; Brain; Disease Models, Animal; Dyrk Kinases; Gene Knock-In Techniques; Humans; Lithium; Male; Mice; Mice, Transgenic; Microcephaly; Mutation; Neurons; Phenotype; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Synapses; lithium; mitogen activated protein kinase phosphatase 1; DYRK kinase; lithium; protein serine threonine kinase; protein tyrosine kinase; animal experiment; animal model; Article; autism; behavior; cognitive defect; controlled study; Dyrk1A deficiency; electrophysiology; female; gene mutation; genotype; haploinsufficiency; hippocampus; human; juvenile; liquid chromatography-mass spectrometry; male; microcephaly; mouse; nerve cell; nonhuman; nuclear magnetic resonance imaging; phenotype; polymerase chain reaction; proteomics; RNA sequencing; synapse; synaptic transmission; transcriptomics; animal; animal behavior; brain; disease model; drug effect; drug therapy; gene knock-in; genetics; metabolism; mutation; nerve cell; phenotype; signal transduction; synapse; transgenic mouse | English | 2025 | 2025-06 | 10.1038/s41380-024-02865-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Polygenic Risk Score and Lung Adenocarcinoma Risk Among Never-Smokers by EGFR Mutation Status: A Brief Report | We assessed the association between a genome-wide polygenic risk score (PRS) developed for lung adenocarcinoma (LUAD) risk and mutation on the EGFR gene in 998 East Asian never-smoking female LUAD cases (518 EGFR-positive; 480 EGFR-negative) and 4544 never-smoking controls using case-case and multinomial regression analyses. We found that the PRS was more strongly associated with EGFR-positive LUAD compared with EGFR-negative LUAD, where the association between the fourth quartile of the PRS and EGFR-positive LUAD (odds ratio = 8.63, 95% confidence interval: 5.67-13.14) was significantly higher than the association between the fourth quartile of the PRS with EGFR-negative LUAD (odds ratio = 3.50, 95% confidence interval: 2.44-5.00) (p-heterogeneity = 3.66 x 10(-3)). Our findings suggest that germline genetic susceptibility may be differentially associated with LUAD in never-smoking female East Asian patients depending on the cancer's mutation status, which may have important public health and clinical implications. (c) 2024 Published by Elsevier Inc. on behalf of International Association for the Study of Lung Cancer. | Blechter, Batel; Hsiung, Chao Agnes; Wang, Xiaoyu; Zhang, Haoyu; Seow, Wei Jie; Shi, Jianxin; Chatterjee, Nilanjan; Kim, Hee Nam; Wong, Maria Pik; Hong, Yun-Chul; Wong, Jason Y. Y.; Dai, Juncheng; Hosgood, H. Dean; Wang, Zhaoming; Chang, I-Shou; Choi, Jiyeon; Wang, Jiucun; Song, Minsun; Hu, Wei; Zheng, Wei; Kim, Jin Hee; Zhou, Baosen; Albanes, Demetrius; Shin, Min-Ho; Chung, Lap Ping; An, She-Juan; Zheng, Hong; Yatabe, Yasushi; Zhang, Xu-Chao; Kim, Young Tae; Shu, Xiao-Ou; Kim, Young-Chul; Vermeulen, Roel C. H.; Bassig, Bryan A.; Chang, Jiang; Ho, James Chung Man; Ji, Bu-Tian; Kubo, Michiaki; Daigo, Yataro; Momozawa, Yukihide; Kamatani, Yoichiro; Honda, Takayuki; Kunitoh, Hideo; Watanabe, Shun-ichi; Miyagi, Yohei; Nakayama, Haruhiko; Matsumoto, Shingo; Tsuboi, Masahiro; Goto, Koichi; Yin, Zhihua; Takahashi, Atsushi; Goto, Akiteru; Minamiya, Yoshihiro; Shimizu, Kimihiro; Tanaka, Kazumi; Wu, Tangchun; Wei, Fusheng; Su, Jian; Kim, Yeul Hong; Oh, In-Jae; Lee, Victor Ho Fun; Su, Wu-Chou; Chen, Yuh-Min; Chang, Gee-Chen; Chen, Kuan-Yu; Huang, Ming-Shyan; Lin, Hsien-Chih; Seow, Adeline; Park, Jae Yong; Kweon, Sun-Seog; Chen, Chien-Jen; Gao, Yu-Tang; Wu, Chen; Qian, Biyun; Lu, Daru; Liu, Jianjun; Jeon, Hyo-Sung; Hsiao, Chin-Fu; Sung, Jae Sook; Tsai, Ying-Huang; Jung, Yoo Jin; Guo, Huan; Hu, Zhibin; Chen, Tzu-Yu; Burdett, Laurie; Yeager, Meredith; Hutchinson, Amy; Berndt, Sonja I.; Wu, Wei; Wang, Junwen; Choi, Jin Eun; Park, Kyong Hwa; Sung, Sook Whan; Liu, Li; Kang, Chang Hyun; Chen, Chung-Hsing; Xu, Jun; Guan, Peng; Tan, Wen; Wang, Chih-Liang; Sihoe, Alan Dart Loon; Chen, Ying; Choi, Yi Young; Kim, Jun Suk; Yoon, Ho-Il; Cai, Qiuyin; Park, In Kyu; Xu, Ping; He, Qincheng; Chen, Chih-Yi; Wu, Junjie; Lim, Wei-Yen; Chen, Kun-Chieh; Chan, John K. C.; Li, Jihua; Chen, Hongyan; Yu, Chong-Jen; Jin, Li; Fraumeni, Joseph F., Jr.; Liu, Jie; Landi, Maria Teresa; Yamaji, Taiki; Yang, Yang; Hicks, Belynda; Wyatt, Kathleen; Li, Shengchao A.; Ma, Hongxia; Song, Bao; Wang, Zhehai; Cheng, Sensen; Li, Xuelian; Ren, Yangwu; Iwasaki, Motoki; Zhu, Junjie; Jiang, Gening; Fei, Ke; Wu, Guoping; Chien, Li-Hsin; Tsai, Fang-Yu; Yu, Jinming; Stevens, Victoria L.; Yang, Pan-Chyr; Lin, Dongxin; Chen, Kexin; Wu, Yi-Long; Matsuo, Keitaro; Rothman, Nathaniel; Shiraishi, Kouya; Shen, Hongbing; Chanock, Stephen J.; Kohno, Takashi; Lan, Qing | NCI, Div Canc Epidemiol & Genet, 9609 Med Ctr Dr, Rockville, MD 20850 USA; Natl Hlth Res Inst, Inst Populat Hlth Sci, Zhunan, Taiwan; Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore; Natl Univ Hlth Syst, Singapore, Singapore; Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore; Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD USA; Johns Hopkins Bloomberg Sch Publ Hlth, Dept Biostat, Baltimore, MD USA; Chonnam Natl Univ, Sch Med, Dept Prevent Med, Gwangju, South Korea; Queen Mary Hosp, Dept Pathol, Hong Kong, Peoples R China; Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea; NHLBI, Epidemiol & Community Hlth Branch, Bethesda, MD USA; Nanjing Med Univ, Sch Publ Hlth, Dept Epidemiol, Nanjing, Peoples R China; Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, New York, NY USA; St Jude Childrens Res Hosp, Dept Computat Biol, Memphis, TN USA; Natl Hlth Res Inst, Natl Inst Canc Res, Zhunan, Taiwan; Fudan Univ, Sch Life Sci, Minist Educ, Key Lab Contemporary Anthropol, Shanghai, Peoples R China; Fudan Univ, Sch Life Sci, State Key Lab Genet Engn, Shanghai, Peoples R China; Sookmyung Womens Univ, Dept Stat, Seoul, South Korea; Sookmyung Womens Univ, Res Inst Nat Sci, Seoul, South Korea; Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN USA; Vanderbilt Ingram Canc Ctr, Nashville, TN USA; Seoul Natl Univ, Grad Sch Publ Hlth, Dept Environm Hlth, Seoul, South Korea; China Med Univ, Hosp 1, Dept Clin Epidemiol, Shenyang, Peoples R China; China Med Univ, Hosp 1, Ctr Evidence Based Med, Shenyang, Peoples R China; Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea; Southern Med Univ, Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Guangdong Lung Canc Inst,Guangdong Prov Key Lab, Guangzhou, Peoples R China; Tianjin Med Univ, Tianjin Med Univ Canc Inst & Hosp, Key Lab Prevent & Control Human Major Dis, Dept Epidemiol & Biostat,Minist Educ,Natl Clin Re, Tianjin, Peoples R China; Natl Canc Ctr, Dept Pathol & Clin Labs, Tokyo, Japan; Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Canc Res Inst, Seoul, South Korea; Chonnam Natl Univ Hwasun Hosp, Lung & Esophageal Canc Clin, Hwasuneup, South Korea; Univ Utrecht, Inst Risk Assessment Sci IRAS, Div Environm Epidemiol, Utrecht, Netherlands; Inova Hlth Syst, Inova Schar Canc Inst, Saville Canc Screening & Prevent Ctr, Fairfax, VA USA; Chinese Acad Med Sci & Peking Union Med Coll, Canc Inst & Hosp, Dept Etiol & Carcinogenesis, Beijing, Peoples R China; Univ Hong Kong, Sch Clin Med, Queen Mary Hosp, Dept Med, Hong Kong, Peoples R China; RIKEN Ctr Integrat Med Sci, Lab Genotyping Dev, Yokohama, Kanagawa, Japan; Univ Tokyo, Inst Med Sci, Res Hosp, Ctr Antibody & Vaccine Therapy, Tokyo, Japan; Shiga Univ Med Sci, Dept Med Oncol, Shiga, Japan; Shiga Univ Med Sci, Ctr Canc, Shiga, Japan; Shiga Univ Med Sci, Ctr Adv Med Canc, Shiga, Japan; RIKEN Ctr Integrat Med Sci, Lab Stat Anal, Yokohama, Kanagawa, Japan; Tokyo Med & Dent Univ, Dept Resp Med, Tokyo, Japan; Japanese Red Cross Med Ctr, Dept Med Oncol, Tokyo, Japan; Natl Canc Ctr, Dept Thorac Surg, Tokyo, Japan; Kanagawa Canc Ctr Res Inst, Mol Pathol & Genet Div, Yokohama, Kanagawa, Japan; Kanagawa Canc Ctr, Dept Thorac Surg, Yokohama, Kanagawa, Japan; Natl Canc Ctr Hosp East, Dept Thorac Oncol, Kashiwa, Chiba, Japan; Natl Canc Ctr Hosp East, Dept Thorac Surg, Kashiwa, Chiba, Japan; China Med Univ, Sch Publ Hlth, Dept Epidemiol, Shenyang, Peoples R China; Akita Univ, Grad Sch Med, Dept Cellular & Organ Pathol, Akita, Japan; Akita Univ, Grad Sch Med, Dept Thorac Surg, Akita, Japan; Shinshu Univ, Sch Med Asahi, Div Gen Thorac Surg, Dept Surg, Nagano, Japan; Gunma Univ Hosp, Dept Integrat Ctr Gen Surg, Maebashi, Gumma, Japan; Huazhong Univ Sci & Technol, Sch Publ Hlth, Inst Occupat Med, Wuhan, Peoples R China; Huazhong Univ Sci & Technol, Sch Publ Hlth, Minist Educ, Key Lab Environm & Hlth, Wuhan, Peoples R China; China Natl Environm Monitoring Ctr, Beijing, Peoples R China; Korea Univ, Anam Hosp, Coll Med, Dept Internal Med,Div Oncol Hematol, Seoul, South Korea; Univ Hong Kong, Queen Mary Hosp, Dept Clin Oncol, Hong Kong, Peoples R China; Natl Cheng Kung Univ, Coll Med, Natl Cheng Kung Univ Hosp, Dept Oncol, Tainan, Taiwan; Taipei Vet Gen Hosp, Dept Chest Med, Taipei, Taiwan; Natl Yang Ming Chiao Tung Univ, Sch Med, Taipei, Taiwan; Chung Shan Med Univ, Sch Med, Taichung, Taiwan; Chung Shan Med Univ, Inst Med, Taichung, Taiwan; Chung Shan Med Univ Hosp, Div Pulm Med, Dept Internal Med, Taichung, Taiwan; Natl Chung Hsing Univ, Inst Biomed Sci, Taichung, Taiwan; Taichung Vet Gen Hosp, Div Chest Med, Dept Internal Med, Taichung, Taiwan; Natl Taiwan Univ Hosp & Coll Med, Dept Internal Med, Taipei, Taiwan; I Shou Univ, Dept Internal Med, E Da Canc Hosp, Kaohsiung, Taiwan; Kaohsiung Med Univ, Kaohsiung, Taiwan; Natl Hlth Res Inst, Inst Populat Hlth Sci, Zhunan, Taiwan; Kyungpook Natl Univ, Med Ctr, Lung Canc Ctr, Daegu, Taiwan; Chonnam Natl Univ, Jeonnam Reg Canc Ctr, Hwasun, South Korea; Acad Sinica, Genom Res Ctr, Taipei, Taiwan; Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China; Chinese Acad Med Sci & Peking Union Med Coll, Dept Etiol & Carcinogenesis, Canc Inst & Hosp, Beijing, Peoples R China; Chinese Acad Med Sci & Peking Union Med Coll, State Key Lab Mol Oncol, Canc Inst & Hosp, Beijing, Peoples R China; Genome Inst Singapore, Dept Human Genet, Singapore, Singapore; Anhui Med Univ, Sch Life Sci, Hefei, Peoples R China; Kyungpook Natl Univ, Med Ctr, Canc Res Ctr, Daegu, South Korea; Chang Gung Univ, Dept Resp Therapy, Taoyuan, Taiwan; Xiamen Chang Gung Hosp, Dept Pulm & Crit Care, Xiamen, Peoples R China; Seoul Natl Univ, Canc Res Inst, Coll Med, Dept Thorac & Cardiovasc Surg, Seoul, South Korea; Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Occupat & Environm Hlth, Wuhan, Peoples R China; Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan, Peoples R China; Nanjing Med Univ, Sch Publ Hlth, Dept Epidemiol, Nanjing, Peoples R China; Leidos Biomed Res Inc, Frederick Natl Lab Canc Res, Canc Genom Res Lab, Rockville, MD USA; China Med Univ, Sch Publ Hlth, Dept Epidemiol, Shenyang, Peoples R China; Univ Hong Kong, Fac Dent, Div Appl Oral Sci & Community Dent Care, Hong Kong, Peoples R China; Univ Hong Kong, State Key Lab Pharmaceut Biotechnol, Hong Kong, Peoples R China; Univ Hong Kong, Lab Pharmaceut Biotechnol, Hong Kong, Peoples R China; Huazhong Univ Sci & Technol, Union Hosp, Ctr Canc, Dept Oncol, Wuhan, Peoples R China; Seoul Natl Univ, Coll Med, Canc Res Inst, Dept Thorac & Cardiovasc Surg, Seoul, South Korea; Natl Hlth Res Inst, Natl Inst Canc Res, Zhunan, Taiwan; Univ Hong Kong, Li Ka Shing LKS Fac Med, Sch Publ Hlth, Hong Kong, Peoples R China; Univ Liaoning Prov, Key Lab Canc Etiol & Intervent, Shenyang, Peoples R China; Chang Gung Mem Hosp, Dept Thorac Med, Div Pulm Oncol & Intervent Bronchoscopy, Taoyuan, Taiwan; Korea Univ, Guro Hosp, Coll Med, Dept Internal Med,Div Med Oncol, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea; Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN USA; Vanderbilt Ingram Canc Ctr, Nashville, TN USA; Wuhan Iron & Steel Grp Corp Staff Worker Hosp, Dept Oncol, Wuhan, Peoples R China; Chung Shan Med Univ, Inst Med, Taichung, Taiwan; Queen Elizabeth Hosp, Dept Pathol, Hong Kong, Peoples R China; Qujing Ctr Dis Control & Prevent, Qujing, Peoples R China; Natl Taiwan Univ Hosp, Hsin Chu Branch, Dept Internal Med, Hsinchu, Taiwan; Shandong Acad Med Sci, Shandong Canc Hosp & Inst, Dept Oncol, Jinan, Peoples R China; Natl Canc Ctr Inst Canc Control, Div Epidemiol, Tokyo, Japan; Shanghai Pulm Hosp, Shanghai, Peoples R China; Nanjing Med Univ, Collaborat Innovat Ctr Canc Med, Jiangsu Key Lab Canc Biomarkers Prevent & Treatme, Nanjing, Peoples R China; Shandong Acad Med Sci, Shandong Canc Hosp & Inst, Dept Oncol, Jinan, Peoples R China; Natl Canc Ctr Inst Canc Control, Div Cohort Res, Tokyo, Japan; Chung Yuan Christian Univ, Dept Appl Math, Chong Li, Taiwan; Chung Shan Med Univ Hosp, Dept Surg, Div Thorac Surg, Taichung, Taiwan; Amer Canc Soc, Lab Serv, Decatur, GA USA; Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan; Aichi Canc Ctr Res Inst, Div Mol Med, Nagoya, Aichi, Japan; Natl Inst Canc Res, Div Genome Biol, Tokyo, Japan; Natl Dong Hwa Univ, Dept Appl Math, Hualien, Taiwan; CUHK Med Ctr, Hong Kong, Peoples R China | Wang, Zhaoming/JMC-3436-2023; Berndt, Sonja/J-8423-2016; Kweon, Sun-Seog/AAZ-4732-2021; Sung, Jae/AAA-3882-2021; Hsiung, Chao/E-3994-2010; Hsiao, Chin-Fu/E-3993-2010; Chen, Kexin/ISV-0772-2023; wang, chih-liang/GSD-6038-2022; Chang, I-Shou/D-2084-2010; YATABE, Yasushi/J-6461-2014; Chanock, Stephen/AGL-9345-2022; Kang, Chang-Hyun/J-5364-2012; Oh, In-Jae/AAG-5919-2020; Kim, Young/X-4588-2019; Han, Liang/KFR-6745-2024; Chen, Hongyan/Y-3514-2019; An, Shejuan/A-9573-2014; Lilly, Christa/R-6644-2017; , 박인규/AGN-7088-2022; Shu, Xiao'Ou/KPA-5613-2024; Yi-Wen, Chen/G-7275-2016; Yoon, Ho/J-5567-2012; Jung, Yoo Jin/LZH-2054-2025 | 57202401910; 57202456495; 59385030800; 57193512183; 55511075900; 57193324786; 7004286059; 7410134504; 7403907887; 7403393231; 19336599300; 26643801800; 56353204400; 35346086300; 7201742359; 56090932200; 57221357827; 56723259300; 56452009900; 56393517800; 57388535100; 7401906866; 7006558522; 7401537616; 24315879100; 9736350600; 56440556100; 7005949450; 55907845000; 59289300400; 57211229380; 35201246200; 57200868939; 36700998400; 55716798500; 59511649700; 7102566147; 57216067537; 7004496677; 8628928100; 23018337900; 57418909600; 7003627919; 8690912300; 7103148659; 7401579827; 58880551500; 55450411000; 7403193692; 35335594700; 57207904643; 7202295543; 35519076100; 7404959449; 55523796200; 57210818519; 7202453127; 26644540200; 57221436158; 58754601500; 59511649800; 57154874700; 57202203104; 7402308947; 59609874800; 56440518700; 15723926900; 56153247800; 58360293800; 7003824608; 57211727643; 7404704976; 16231904800; 22954132500; 57223736435; 57208523547; 7201833632; 7202806660; 17344561900; 7402627938; 55446683300; 35754492500; 57217720913; 57209880712; 22949983300; 35379327500; 35381552100; 8551151700; 57202196681; 58199357400; 37107028100; 7408065807; 59748818600; 57295589300; 57218662804; 26025855000; 7407002243; 7006168914; 7401959984; 35486120300; 57191403086; 36106935200; 8547187300; 7601366116; 57391933700; 57226662482; 56438531400; 57214656722; 56003953300; 57215122538; 55713999100; 35995422500; 8674333600; 56603220900; 36523246000; 55675224344; 59119896800; 57359869600; 35374106200; 55279322700; 57217595332; 7102897776; 56242899700; 57210905802; 57169985800; 57169239600; 8624236700; 9044530900; 8644310300; 56468378900; 57192492699; 39362345600; 9233646600; 58288887900; 59253307900; 15727763400; 55286446300; 56742828600; 26028474900; 57226895340; 57201568161; 58853667400; 57216429543; 57216428242; 55569782000; 57213117864; 34572851700; 7202509586; 57218362875; 57216984275; 7201820330; 23970641100 | batel.blechter@nih.gov; | JOURNAL OF THORACIC ONCOLOGY | J THORAC ONCOL | 1556-0864 | 1556-1380 | 20 | 4 | SCIE | ONCOLOGY;RESPIRATORY SYSTEM | 2024 | 20.8 | 2.3 | 0 | 2025-05-07 | 0 | 0 | Lung adenocarcinoma; Never-smokers; EGFR mutation; Polygenic risk score | CANCER | EGFR mutation; Lung adenocarcinoma; Never-smokers; Polygenic risk score | Adenocarcinoma of Lung; Aged; Case-Control Studies; ErbB Receptors; Female; Genetic Predisposition to Disease; Genetic Risk Score; Humans; Lung Neoplasms; Middle Aged; Multifactorial Inheritance; Mutation; Non-Smokers; Prognosis; Risk Factors; epidermal growth factor receptor; EGFR protein, human; epidermal growth factor receptor; adult; Article; Bayesian network; cancer risk; cigarette smoking; DNA extraction; female; gene; gene frequency; gene linkage disequilibrium; gene mutation; genetic association; genetic polymorphism; genetic risk; genetic risk score; genetic susceptibility; genetic variability; genetic variation; genome-wide association study; genotype; genotyping; germline mutation; human; lung adenocarcinoma; major clinical study; never smoker; phenotype; risk factor; sensitivity analysis; single nucleotide polymorphism; smoking; aged; case control study; genetic predisposition; genetic risk score; genetics; lung tumor; middle aged; multifactorial inheritance; mutation; non-smoker; pathology; prognosis | English | 2025 | 2025-04 | 10.1016/j.jtho.2024.11.019 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Reagentless aptamer based on the ultrasensitive and fast response electrochemical capacitive biosensor for EGFR detection in non-small cell lung cancer | Non-small cell lung cancer (NSCLC) is still the leading cause of lung cancer-related deaths globally, affecting both men and women. Mutations in the epidermal growth factor receptor (EGFR) are most common among patients with NSCLC, especially Asian patients. Here, we introduce an electrochemical capacitive biosensor for the early detection of NSCLC through specific identification of EGFR. A novel and reagentless EGFR aptamer was designed using the systematic evolution of ligands by exponential enrichment (SELEX) process and immobilized on a chromium (Cr)/gold (Au) electrode, with capacitance signals used for detection. The biosensor employs an interdigitated capacitor electrode (IDCE) functionalized with 3-mercaptopropionic acid (MPA), enhancing EGFR aptamer immobilization, while 6-mercapto-1-hexanol (MCH) was used for effective blocking to ensure robust and high-affinity binding to target analytes. The IDCE capacitive biosensor achieved real-time rapid detection within 3 s and demonstrated a detection limit of 0.005 ng/mL for the EGFR peptide, with a dynamic range of 10_ 11-10_ 7 ng/mL. Furthermore, the specific EGFR aptamer-immobilized IDCE biosensor was found to be regenerable and reusable up to five times using deionized water. This biosensor offers a rapid, label-free, and highly selective approach for early-stage EGFR detection in NSCLC. Its portability and scalability make it a promising tool for point-of-care diagnostic applications in biomedicine, potentially advancing the field of cancer diagnostics. | Ganbold, Enkhzaya; Kim, Nam Young; Kim, Yu Mi; Sharma, Parshant Kumar; Lee, Do Nam; Oh, Byeolnim; Kim, Hyun Soo; Song, Junghan; Lee, Byungheon; Kim, Eun-Seong; Shin, Young Kee; Park, Jeong Su; Kim, Sang Tae | Kwangwoon Univ, RF Bio Ctr, 20 Kwangwoon ro, Seoul 01897, South Korea; Kwangwoon Univ, Dept Elect Engn, 20 Kwangwoon Ro, Seoul 01897, South Korea; Kwangwoon Univ, NDAC Ctr, 20 Kwangwoon Ro, Seoul 01897, South Korea; Kwangwoon Univ, Ingenium Coll Liberal Arts Chem, 20 Kwangwoon ro, Seoul 01897, South Korea; Seoul Natl Univ, Coll Med, JnPharma Inc, Neurosci Res Inst,Healthcare Innovat Pk, Seongnam City 13605, Gyeonggi Do, South Korea; Seoul Natl Univ, Dept Lab Med, Bundang Hosp, Seongnam City 13605, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biochem, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Seoul Natl Univ, Dept Mol Med & Biopharmaceut Sci, Seoul 08826, South Korea | Sharma, Parshant/ACL-0110-2022; Kim, Eun Seong/B-8288-2019; Sharma, Parshant Kumar/ACL-0110-2022 | 57264012100; 23060849600; 59447410400; 57219901255; 8556814000; 57768104300; 58459296900; 7404788093; 59812800700; 56504232000; 26428533000; 58452307800; 37052303200 | 3037eskim@gmail.com; ykeeshin@snu.ac.kr; lingokst@snu.ac.kr; | BIOSENSORS & BIOELECTRONICS | BIOSENS BIOELECTRON | 0956-5663 | 1873-4235 | 278 | SCIE | BIOPHYSICS;CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;NANOSCIENCE & NANOTECHNOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2024 | 10.5 | 2.3 | 0 | 2025-05-07 | 1 | 1 | EGFR detection in non-small cell lung cancer; Regenerable aptamer; Reusable interdigitated capacitor electrode; Rapid detection; Biomedical application | GROWTH-FACTOR RECEPTOR; MUTATIONS; QUANTIFICATION; IMMUNOSENSOR | Biomedical application; EGFR detection in non-small cell lung cancer; Rapid detection; Regenerable aptamer; Reusable interdigitated capacitor electrode | Aptamers, Nucleotide; Biosensing Techniques; Carcinoma, Non-Small-Cell Lung; Electrochemical Techniques; Electrodes; ErbB Receptors; Gold; Humans; Limit of Detection; Lung Neoplasms; SELEX Aptamer Technique; Biological organs; Capacitor bank; Cell death; Deionized water; 3 mercaptopropionic acid; aptamer; chromium; dimeticone; epidermal growth factor receptor; gold; EGFR protein, human; epidermal growth factor receptor; Aptamers; Biomedical applications; Capacitor electrode; Epidermal growth factor receptor detection in non-small cell lung cancer; Epidermal growth factor receptors; Interdigitated capacitors; Non small cell lung cancer; Rapid detection; Regenerable aptamer; Reusable interdigitated capacitor electrode; A-431 cell line; adult; animal experiment; Article; atomic force microscopy; binding affinity; biomedicine; cell proliferation assay; confocal laser scanning microscopy; confocal microscopy; controlled study; diagnostic test accuracy study; energy dispersive X ray spectroscopy; female; flow cytometry; Fourier transform infrared spectroscopy; gene expression; gene mutation; HCC827 cell line; human; human cell; immobilization; Jurkat cell line; limit of detection; male; mouse; NCI-H1975 cell line; non small cell lung cancer; nonhuman; point of care testing; protein expression; protein secondary structure; real time polymerase chain reaction; sensitivity and specificity; X ray photoemission spectroscopy; chemistry; devices; diagnosis; electrochemical analysis; electrode; genetic procedures; genetics; lung tumor; procedures; systematic evolution of ligands by exponential enrichment aptamer technique; Lung cancer | English | 2025 | 2025-06-15 | 10.1016/j.bios.2025.117319 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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