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○ | ○ | Article | Smart traffic control: Identifying driving-violations using fog devices with vehicular cameras in smart cities | Growing vehicular traffic in urban areas creates a mess for authorities to handle city traffic. With the lack of human resources, authorities are moving towards the use of smart and auto-traffic control systems to manage an increasing volume of traffic. Mostly, these systems monitor traffic using street cameras and identify illegal traffic behaviors, such as signal violations. However, it is not feasible to employ humans or static cameras everywhere in the city in order to cover all the urban roads. These days, modern automobiles come with cameras to store videos as a black-box in case of an accident. In this paper, we exploited the use of vehicular cameras and proposed a smart traffic control model to report any traffic violation on the road. To this end, the vehicle's camera monitors all front cars on the road and transmits videos to the car's attached fog device. The fog device analyses the captured video for unlawful behavior and reports to traffic authorities in case of any violation. Initially, front vehicles are recognized using Single Shot MultiBox Detector (SSD), whereas road lanes are marked using Hough transform. Later, the violations are identified using the violation-detection algorithm. As a use case, the algorithm is designed for the fog device to identify driving violations, including wrong U-turn and driving on a central divider line or a yellow line. The role of the fog device is implemented on a GTX750-Ti GPU-based machine. Finally, the system's performance is evaluated in terms of accuracy and efficiency. | Rathore, M. Mazhar; Paul, Anand; Rho, Seungmin; Khan, Murad; Vimal, S.; Shah, Syed Attique | Hamad Bin Khalifa Univ, Div Informat & Comp Technol, Coll Sci & Engn, Doha, Qatar; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Chung Ang Univ, Dept Ind Secur, Seoul, South Korea; Ramco Inst Technol, Dept CSE, Rajapalayam, Tamil Nadu, India; Univ Tartu, Data Syst Grp, Delta Ctr, Inst Comp Sci, Narva Mnt 18-3123, EE-51009 Tartu, Estonia | ; Shah, Syed Attique/ABD-6564-2021; SHANMUGANATHAN, VIMAL/E-9551-2016; Rho, Seungmin/HTP-6683-2023; Paul, Anand/V-6724-2017 | 56650727000; 56650522400; 10738984000; 56151971600; 57150956300; 57194554620 | mrathore@hbku.edu.qa;paul.editor@gmail.com;smrho@cau.ac.kr;muradkhan23@gmail.com;svimalphd@gmail.com;syed.shah@ut.ee; | SUSTAINABLE CITIES AND SOCIETY | SUSTAIN CITIES SOC | 2210-6707 | 2210-6715 | 71 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENERGY & FUELS;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2021 | 10.696 | 2.2 | 2.73 | 2025-07-30 | 33 | 50 | Smart city; Traffic governance and control; Lane detection; Mobile video processing; Vehicle detection | REAL-TIME; VEHICLE DETECTION; CAR DETECTION; IMAGES; CITY; INFORMATION; FRAMEWORK | Lane detection; Mobile video processing; Smart city; Traffic governance and control; Vehicle detection | Hough transforms; Roads and streets; Street traffic control; Vehicles; Video cameras; Video signal processing; City traffic; Lane detection; Mobile video processing; Smart traffic; Systems monitor; Traffic behavior; Traffic control systems; Traffic governance and control; Urban areas; Vehicles detection; algorithm; detection method; smart city; traffic management; transport vehicle; videography; Smart city | English | 2021 | 2021-08 | 10.1016/j.scs.2021.102986 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
○ | ○ | Editorial Material | Social, mobile, analytic and cloud technologies: Intelligent Computing for future smart cities | Nayyar, Anand; Paiva, Sara; Paul, Anand; Kumar, Akshi | Duy Tan Univ, Da Nang, Vietnam; Inst Politecn Viana do Castelo, Viana Do Castelo, Portugal; Kyungpook Natl Univ, Daegu, South Korea; Delhi Technol Univ, New Delhi, India | ; Kumar, Akshi/Y-9314-2019; Paul, Anand/V-6724-2017; Nayyar, Anand/F-3732-2015; Paiva, Sara/O-9328-2015 | 55201442200; 36447905300; 56650522400; 56718788600 | anandnayyar@duytan.edu.vn;sara.paiva@estg.ipvc.pt;Paul.editor@gmail.com;akshikumar@dce.ac.in; | SUSTAINABLE CITIES AND SOCIETY | SUSTAIN CITIES SOC | 2210-6707 | 2210-6715 | 66 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENERGY & FUELS;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2021 | 10.696 | 2.2 | 1.04 | 2025-07-30 | 0 | 2 | computer simulation; genetic algorithm; smart city; urban development; urban planning | English | 2021 | 2021-03 | 10.1016/j.scs.2020.102676 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
○ | ○ | Article | 3D-structured soft bioelectronic devices with crack-free metal patterns | Three-dimensionally (3D) structured soft electronic devices that fit the contour of target organs or tissues are preferred for the stable implantation of biomedical devices. However, the metal patterns deposited on soft materials, especially polydimethylsiloxane (PDMS), can generate microcracks or disconnections following an expansion of the substrate. A way to generate 3D structured soft devices is using fluid injection into the unbonded area of a selectively bonded 2D structure comprised of PDMS and parylene layers. This work outlines the development of 3D soft bioelectronic devices, including the fabrication processes optimized for stable metal patterns even after substrate expansion via fluid injection. The generation of cracks in metal patterns was significantly affected by the sputtered material for plasma mask during the selective bonding process and the thickness of the intermediate parylene layer used underneath the sputtered metal. An RF-sputtered titanium mask was chosen to create crack-free metal patterns on the intermediate parylene layer based on PDMS substrate. Moreover, the thickness of the intermediate parylene layer was optimized using finite element analysis for stable and intact metal patterns after fluid injection. The developed soft bioelectronic device successfully demonstrated the ability to record and stimulate the peripheral nerve in vivo as cuff electrodes. The optimized processes developed in this study not only enable soft 3D electronic devices applicable to internal organs or tissues with 3D curvatures, but also suggest a promising way to fabricate flexible electronics using conventional micromachining processes such as photolithography and metal sputtering on soft and expandable substrates. | Moon, Hyunmin; Park, Byungwook; Hong, Daun; Park, Ki-Su; Lee, Sanghoon; Kim, Sohee | Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept Robot Engn, Daegu 42988, South Korea; Kyungpook Natl Univ, Dept Neurosurg, Sch Med, Daegu 41944, South Korea | Kim, Sohee/N-4123-2017; Moon, HyunMin/R-7853-2019 | 57191245161; 57223900884; 57223886488; 55932363100; 57216696166; 55958147000 | soheekim@dgist.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 343 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2021 | 9.221 | 2.3 | 0.71 | 2025-07-30 | 11 | 12 | Soft electronics; Flexible electronics; Bioelectronics; Crack-free metal patterns; Substrate expansion; 3D structured device | STIMULATION; ELECTRODE; ARRAY; PDMS | 3D structured device; Bioelectronics; Crack-free metal patterns; Flexible electronics; Soft electronics; Substrate expansion | Expansion; Flexible electronics; Histology; Microchannels; Microcracks; Micromachining; Polydimethylsiloxane; Silicones; Substrates; Thermoelectric equipment; Tissue; 3d structured device; Bioelectronic; Bioelectronic device; Crack free; Crack-free metal pattern; Fluid injections; Metal patterns; Parylenes; Soft electronics; Substrate expansion; Metals | English | 2021 | 2021-09-15 | 10.1016/j.snb.2021.130123 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Meeting Abstract | A case of atypical hemolytic uremic syndrome caused by Escherichia fergusonii mimicking Escherichia coli in an immunocompetent adult | Hwang, Soyoon; Chang, Hyun-Ha; Kim, Yu Kyung; Kim, Jungmin | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Microbiol, Daegu, South Korea | Kim, Young-Il/ISS-7678-2023 | 57203160675; 7407521688; 9237571900; 57211297681 | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | INT J ANTIMICROB AG | 0924-8579 | 1872-7913 | 58 | SCIE | INFECTIOUS DISEASES;MICROBIOLOGY;PHARMACOLOGY & PHARMACY | 2021 | 15.441 | 2.3 | 0.18 | 2025-07-30 | 0 | 2 | Hemolytic uremic syndrome; Escherichia fergusonii | Escherichia fergusonii.; Hemolytic uremic syndrome | English | 2021 | 2021-09 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||
○ | Meeting Abstract | Association between antacid proton pump inhibitors and histamine 2 receptor antagonists) and incidence of lung cancer: a population-based cohort analysis | Choi, Won-Il; Jeong, Jihyeon; Lee, Choong Won | Myongji Hosp, Goyang, South Korea; Kyungpook Natl Univ, Daegu, South Korea; Sungso Hosp, Andong, South Korea | choi_wi@hanmail.net; | EUROPEAN RESPIRATORY JOURNAL | EUR RESPIR J | 0903-1936 | 1399-3003 | 58 | SCIE | RESPIRATORY SYSTEM | 2021 | 33.801 | 2.3 | 0 | Lung cancer | English | 2021 | 2021-09-05 | 10.1183/13993003.congress-2021.pa1731 | 바로가기 | 바로가기 | 바로가기 | |||||||||||||
○ | ○ | Meeting Abstract | Complicated varicella zoster virus infection in children | Shin, Areum Shin; Choi, Bong Seok; Hwang, SooKyung; Kwon, Soonhak; Kim, Dongsub; Lee, Nan Young | Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu, South Korea | lee, nan/HZM-0321-2023 | 58475791700; 56547873100; 57273454000; 55468232200; 57205248455; 57209204358 | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | INT J ANTIMICROB AG | 0924-8579 | 1872-7913 | 58 | SCIE | INFECTIOUS DISEASES;MICROBIOLOGY;PHARMACOLOGY & PHARMACY | 2021 | 15.441 | 2.3 | 0 | 2025-07-30 | 0 | 0 | English | 2021 | 2021-09 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||||
○ | ○ | Article | Functional solid-state photonic droplets with interpenetrating polymer network and their applications to biosensors | Complete solid-state cholesteric liquid crystal (CLCsolid) balls with an semi interpenetrating polymer network (IPN) structure (CLCsolid-IPN) were fabricated using uniformly sized CLCsolid balls intertwined with poly(acrylic acid) (PAA). The CLCsolid balls were produced from a reactive mesogen mixed with a nonreactive chiral dopant using a microfluidic device after ultraviolet curing and dopant extraction. The CLCsolid-IPN balls were prepared by allowing AA monomers to infiltrate the space remaining after dopant removal. The CLCsolid balls could be applied to a small strain sensor because they exhibited excellent elastic properties which led to the reflected color change with the magnitude of the blueshift proportional to the applied strain. The CLC(solid-IPN )balls showed pH responsive color change, which property could be applied to a small pH sensor. The urease-immobilized CLCsolid-IPN (CLCsolid-IPN-urease) balls could be applied to a small urea sensor after urease immobilization. The enzymatic reaction with urea redshifted the reflected color of the CLCsolid-IPN-urease balls because the increase in local pH induced by the enzymatic reaction led to swelling of the intertwined PAA. The highly swollen KOH-treated CLCsolid-IPN (CLCsolid-IPN-KOH) balls were used to sense divalent metal ions. The replacement of K+ ions with divalent metal ions (M) led to a blueshift in the reflected color due to the bridged -COO-M-COO- structure. Thus, the proposed photonic CLCsolid-IPN balls, which are not affected by the viewing angle, represent a potential new sensor platform that can offer simple functionalization, requires only small test samples and does not need sophisticated analytical instruments. | Lim, Ji-Sook; Kim, Ye-Ji; Park, Soo-Young | Kyungpook Natl Univ, Polymer Nano Mat Lab, Sch Appl Chem Engn, Daegu 41566, South Korea | park, soo-young/N-3170-2017 | 57219939001; 57219616711; 57194041850 | psy@knu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 329 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2021 | 9.221 | 2.3 | 1.42 | 2025-07-30 | 20 | 20 | Photonic; Interpenetrating polymer network; Microfluidics; Biosensor; Cholesteric liquid crystal | CALCIUM; MAGNESIUM; HYDROGELS; BIENZYME; PAA | Biosensor; Cholesteric liquid crystal; Interpenetrating polymer network; Microfluidics; Photonic | Blue shift; Cholesteric liquid crystals; Colorimetry; Crystal structure; Metabolism; Metal ions; Metals; Potassium hydroxide; Urea; Analytical instrument; Divalent metal ion; Elastic properties; Enzymatic reaction; Micro-fluidic devices; Semi-interpenetrating polymer networks; Ultraviolet curing; Urease immobilization; pH sensors | English | 2021 | 2021-02-15 | 10.1016/j.snb.2020.129165 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | Gas sensing behavior of p-NiO/n-ZnO composite nanofibers depending on varying p-NiO content: Selectivity and humidity-independence for oxidizing and reducing gas molecules | In this work, we fabricated gas sensors based on p-type NiO/n-type ZnO composite nanofibers (NFs), which could selectively detect oxidizing and reducing gas molecules. The p-type NiO/n-type ZnO composite NFs with both hetero- and homojunctions were successfully synthesized, and their sensing performances for oxidizing and reducing gases were systematically investigated with different composition ratios of p-type NiO and n-type ZnO. Interestingly, for oxidizing and reducing gases, the 0.5NiO-0.5ZnO NFs (nominal composition) exhibited an excellent gas response to oxidizing gases such as NO2 and SO2, whereas the 0.8NiO-0.2ZnO NFs (nominal composition) showed good selectivity for reducing gases such as C3H6O, C2H5OH, and NH3. In addition, we also examined the NO2 and CO sensing performance under a humid atmosphere to confirm the role of the NiO component, which possesses high affinity for water molecules, in p-type NiO/n-type ZnO composite NFs. We discussed the correlation between variations in composition and sensing performances with respect to gas sensing behavior, selectivity, and humidity effect for oxidizing and reducing gases. The results reveal that we successfully imparted selectivity for oxidizing and reducing gas molecules to the p-type NiO/n-type ZnO composite NFs by adjusting the composition ratio of NiO/ZnO. | Jin, Changhyun; Choi, Myung Sik; Lee, Kyu Hyoung; Choi, Sun-Woo | Yonsei Univ, Dept Mat Sci & Engn, Seoul 03722, South Korea; Kyungpook Natl Univ, Sch Nano & Mat Sci & Engn, Gyeongsangbuk Do 37224, South Korea; Kangwon Natl Univ, Dept Mat Sci & Engn, Gangwon Do 25913, South Korea | ; Jin, Changhyun/P-9398-2015; Choi, Myung-Sik/J-5687-2012 | 35177895100; 57190737942; 35205856800; 35106725800 | khlee2018@yonsei.ac.kr;csw0427@kangwon.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 349 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2021 | 9.221 | 2.3 | 1.74 | 2025-07-30 | 26 | 27 | p-NiO; n-ZnO; Composite nanofibers; Selectivity; Humidity independence | ROOM-TEMPERATURE; ALPHA-FE2O3 NANORODS; METAL-OXIDES; N-JUNCTIONS; ULTRA-THIN; SENSORS; NO2; NANOCOMPOSITES; HOLLOW; PERFORMANCE | Composite nanofibers; Humidity independence; n-ZnO; p-NiO; Selectivity | Ammonia; Chemical detection; Chemical sensors; Gas detectors; Gas sensing electrodes; Gases; II-VI semiconductors; Molecules; Nickel oxide; Nitrogen oxides; Zinc oxide; Composite nanofibers; Gas molecules; Humidity independence; N-ZnO; Oxidizing gas; P-NiO; P-type; Reducing gas; Selectivity; Sensing performance; Nanofibers | English | 2021 | 2021-12-15 | 10.1016/j.snb.2021.130813 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | Microneedle array with a pH-responsive polymer coating and its application in smart drug delivery for wound healing | For successful wound treatment, therapeutics must be delivered directly to the wound. Various issues restrict the delivery of antibiotics to wounds, including the barrier mannered by necrotic tissue and biofilms, which create an extracellular polymeric layer that impedes the efficient administration of therapeutics. For achieving break of the necrotic tissue barrier and biofilm, in addition, improving antibiotics penetration through a painless administration, we fabricated porous polymer coatings on microneedles (MNs) which had the ability of automatic "release" therapeutics in response to wound pH conditions. In the pores of the porous polymer film, the model drug was packed using aqueous gelatin porogen, and the porous layer was coated with a Eudragit S100 film to cap the pores to prevent drug leakage and provide a wound pH-responsive drug release. By combining the advantages of porous and pH-responsive polymer coatings, the coated MNs exhibited remarkably enhanced therapeutic results. This formulation showed both in vivo (in rats) and in vitro (in phosphate-buffered saline and in porcine skin) wound pH-sensitive drug release with rapid responsiveness. At healthy skin pH (pH 4.5), an insignificant release was noticed for MNs in the test media. However, drug release considerably increased when MNs were exposed to wound pH conditions (pH 7.5). The present study provides proof-of-concept evidence that developed MNs have the potential of enhanced treatment protocol for wound infections with the flexibility of coating materials and antimicrobials and offers significant scope for further variations and advancement. | Ullah, Asad; Jang, Mijin; Khan, Haroon; Choi, Hye Jin; An, Sanghyun; Kim, Dongseon; Kim, Ye-Ri; Kim, Un-Kyung; Kim, Gyu Man | Kyungpook Natl Univ, Sch Mech Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Biol, Daegu 14566, South Korea; Daegu Gyeongbuk Med Innovat Fdn, Lab Anim Ctr, Daegu 41061, South Korea | Kim, Ji-Youn/A-5779-2017 | 56820305400; 57222997201; 14521310700; 57203969417; 57102583100; 58291623700; 56048344100; 7102248968; 55664733000 | gyuman.kim@knu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 345 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2021 | 9.221 | 2.3 | 4.58 | 2025-07-30 | 65 | 69 | Wound pH-responsive; Microneedles; Porous polymer coating; Automatic release | DRESSINGS; NANOPARTICLES; HYDROGELS; PATCHES | Automatic release; Microneedles; Porous polymer coating; Wound pH-responsive | Biofilms; Controlled drug delivery; Functional polymers; pH; Plastic coatings; Polymer films; Semiconducting films; Targeted drug delivery; Tissue; Automatic release; Drug release; Microneedle arrays; Microneedles; Necrotic tissue; pH condition; pH-Responsive polymer; Polymer Coating; Porous polymer coating; Wound ph-responsive; Needles | English | 2021 | 2021-10-15 | 10.1016/j.snb.2021.130441 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | Mining Fix Patterns for FindBugs Violations | Several static analysis tools, such as Splint or FindBugs, have been proposed to the software development community to help detect security vulnerabilities or bad programming practices. However, the adoption of these tools is hindered by their high false positive rates. If the false positive rate is too high, developers may get acclimated to violation reports from these tools, causing concrete and severe bugs being overlooked. Fortunately, some violations are actually addressed and resolved by developers. We claim that those violations that are recurrently fixed are likely to be true positives, and an automated approach can learn to repair similar unseen violations. However, there is lack of a systematic way to investigate the distributions on existing violations and fixed ones in the wild, that can provide insights into prioritizing violations for developers, and an effective way to mine code and fix patterns which can help developers easily understand the reasons of leading violations and how to fix them. In this paper, we first collect and track a large number of fixed and unfixed violations across revisions of software. The empirical analyses reveal that there are discrepancies in the distributions of violations that are detected and those that are fixed, in terms of occurrences, spread and categories, which can provide insights into prioritizing violations. To automatically identify patterns in violations and their fixes, we propose an approach that utilizes convolutional neural networks to learn features and clustering to regroup similar instances. We then evaluate the usefulness of the identified fix patterns by applying them to unfixed violations. The results show that developers will accept and merge a majority (69/116) of fixes generated from the inferred fix patterns. It is also noteworthy that the yielded patterns are applicable to four real bugs in the Defects4J major benchmark for software testing and automated repair. | Liu, Kui; Kim, Dongsun; Bissyande, Tegawende F.; Yoo, Shin; Le Traon, Yves | Univ Luxembourg, Interdisciplinary Ctr Secur Reliabil & Trust SnT, L-4365 Esch Sur Alzette, Luxembourg; Nanjing Univ Aeronaut & Astronaut, Coll Comp Sci & Technol, Nanjing, Peoples R China; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Korea Adv Inst Sci & Technol, Sch Comp, Daejeon, South Korea | LE TRAON, Yves/T-2911-2019; Yoo, Shin/E-3247-2015; Kim, Dongsun/B-4856-2015 | 57203748234; 55742964600; 36080354200; 20435019400; 55884641800 | kui.liu@nuaa.edu.cn;darkrsw@knu.ac.kr;tegawende.bissyande@uni.lu;shin.yoo@kaist.ac.kr;yves.letraon@uni.lu; | IEEE TRANSACTIONS ON SOFTWARE ENGINEERING | IEEE T SOFTWARE ENG | 0098-5589 | 1939-3520 | 47 | 1 | SCIE | COMPUTER SCIENCE, SOFTWARE ENGINEERING;ENGINEERING, ELECTRICAL & ELECTRONIC | 2021 | 9.322 | 2.3 | 3.24 | 2025-07-30 | 97 | 74 | Fix pattern; pattern mining; program repair; findbugs violation; unsupervised learning | SOURCE CODE; BUGS | findbugs violation; Fix pattern; pattern mining; program repair; unsupervised learning | Computer software; Computer software maintenance; Maintainability; Program debugging; Repair; Software design; Tools; Unsupervised learning; Computer bugs; findbugs violation; Fix pattern; Java; Pattern mining; Security; Static analysis | English | 2021 | 2021-01-01 | 10.1109/tse.2018.2884955 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
○ | ○ | Meeting Abstract | Psychological effects of paramedics by experience of managing COVID-19 patients | Kim, Bongyoung; Hwang, Soyoon; Ryoo, Hyun Wook; Chung, Un Sun; Lee, So Hee; Lee, Ju-Yeon; Shin, Ji-Yeon; Bae, Sang-Geun; Kwon, Ki Tae | Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Emergency Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Psychiatry, Daegu, South Korea; Chonnam Natl Univ, Natl Med Ctr, Dept Psychiat, Gwangju, South Korea; Chonnam Natl Univ, Med Sch, Dept Psychiat, Gwangju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, Daegu, South Korea | Kim, Woo/AAG-1822-2019; Hwang, Soyoon/HHM-5762-2022; Lee, Jung-Seok/L-6826-2019 | 55622077200; 57203160675; 57268129500; 24477437300; 57267920700; 57203144588; 55567961600; 55278023500; 9733850500 | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | INT J ANTIMICROB AG | 0924-8579 | 1872-7913 | 58 | SCIE | INFECTIOUS DISEASES;MICROBIOLOGY;PHARMACOLOGY & PHARMACY | 2021 | 15.441 | 2.3 | 0 | 2025-07-30 | 0 | 0 | English | 2021 | 2021-09 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||||
○ | Article | Quality of life after sphincter preservation surgery or abdominoperineal resection for low rectal cancer (ASPIRE): A long-term prospective, multicentre, cohort study | Background: The long-term effects of radical resection on quality of life may influence the treatment selection. The objective of this study was to determine whether abdominoperineal resection has a better effect on the quality of life than sphincter preservation surgery at 3 years after surgery Methods: This prospective, cohort study included patients who underwent radical resection for low rectal cancer. The primary outcomes were European Organisation for Research and Treatment of Cancer QLQ-C30 and CR38 quality of life scores 3 years after surgery, which were compared with linear generalised estimating equations, after adjustment for baseline values, a time effect, and an interaction effect between time and treatment. The secondary outcomes included sexual-urinary functions and oncological outcomes. The study was registered with ClinicalTrials.gov (NCT01461525). Findings: Between December 2011 and August 2016, 342 patients were enrolled: 268 (78.4%) underwent sphincter preservation surgery and 74 (21.6%) underwent abdominoperineal resection. The global quality of life scores did not differ between sphincter preservation surgery and abdominoperineal resection groups (adjusted mean difference, 4.2 points on a 100-point scale; 95% confidence interval [CI], -1.3 to 9.7, p = 0.1316). Abdominoperineal resection was associated with a worse body image (9.8 points; 95% CI, 2.9 to 16.6, p = 0.0052), micturition symptoms (-8.0 points; 95% CI, -14.1 to -1.8, p = 0.0108), male sexual problems (-19.9 points; 95% CI, -33.1 to -6.7, p = 0.0032), less confidence in getting and maintaining an erection in males (0.5 points on a 5-point scale; 95% CI, 0.1 to 0.8, p = 0.0155), and worse urinary symptoms (-5.4 points on a 35-point scale; 95% CI, -8.0 to -2.7, p < 0.0001). The 5-year overall survival was worse with abdominoperineal resection in unadjusted (92.2% vs 80.9%; difference 11.3%, hazard ratio 2.38; 95% CI, 1.27 to 4.46, p = 0.0052), but did not differ after adjustment. Interpretation: In this long-term prospective study, abdominoperineal resection failed to meet the superiority to sphincter preservation surgery in terms of quality of life. Although the global quality of life scores did not differ between groups, this study suggests that sphincter preservation surgery can be an acceptable alternative to abdominoperineal resection for low rectal cancer, offering a better quality of life and sexual-urinary functions, with no increased oncological risk even after 3 years. (C) 2020 The Author(s). Published by Elsevier Ltd. | Kang, Sung-Bum; Cho, Jung Rae; Jeong, Seung-Yong; Oh, Jae Hwan; Ahn, Soyeon; Choi, Sunkyu; Kim, Duck-Woo; Lee, Bong Hwa; Youk, Eui Gon; Park, Sung Chan; Heo, Seung Chul; Lee, Doo-Seok; Ryoo, Seung-Bum; Park, Ji Won; Park, Hyoung-Chul; Lee, Sung-Min; Kang, Sung Il; Kim, Min Hyun; Oh, Heung-Kwon; Shin, Rumi; Kim, Min Jung; Lee, Kyoung Ho; Kim, Young-Hoon; Kim, Jae-Sung; Lee, Keun-Wook; Lee, Hye Seung; Kim, Hyun Jung; Park, Young Soo; Sohn, Dae Kyung; Park, Kyu Joo | Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Surg, Seongnam, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea; Yeungnam Univ, Med Ctr, Daegu, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Div Colorectal Surg,Dept Surg, Seoul, South Korea; Natl Canc Ctr, Res Inst & Hosp, Ctr Colorectal Canc, Goyang, South Korea; Seoul Natl Univ, Bundang Hosp, Med Res Collaborating Ctr, Seongnam, South Korea; Korea Univ, Coll Med, Seoul, South Korea; Hallym Univ, Hallym Univ Hosp, Coll Med, Dept Surg, Anyang, South Korea; Clean Seoul Clin, Seoul, South Korea; Natl Canc Ctr, Goyang, South Korea; Daehang Hosp, Dept Surg, Seoul, South Korea; Good Jang Hosp, Seoul, South Korea; Seoul Natl Univ, Seoul Metropolitan Govt, Boramae Med Ctr, Dept Surg, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Radiol, Seongnam, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Radiat Oncol, Seongnam, South Korea; Seoul Natl Univ, Coll Med, Bundang Hosp, Dept Internal Med, Seongnam, South Korea; Seoul Natl Univ, Coll Med, Bundang Hosp, Dept Pathol, Seongnam, South Korea; Korea Univ, Coll Med, Dept Prevent Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Gastroenterol, Seongnam, South Korea | Lee, Hye Seung/LZI-3726-2025; Park, Young/J-5491-2012; Kim, Hyunjung/NPI-3943-2025; Kim, Jee/J-5441-2012; Kim, Min/AAF-1208-2019; Kim, Young-Hoon/E-5614-2012; Park, Ji Won/JCD-9105-2023; Kim, Jae-Sung/J-5429-2012; Ryoo, Seung-Bum/AGL-0507-2022; Jeong, Seung-Yong/J-5643-2012; Oh, Heung-Kwon/S-1292-2019; Lee, Juhyung/JQV-8143-2023; Lee, Kyoung/J-5570-2012; Park, Kyu/J-5480-2012; Kwak, Sang Gyu/AAG-4341-2021 | kangsb@snubh.org; | LANCET REGIONAL HEALTH-WESTERN PACIFIC | LANCET REG HEALTH-W | 2666-6065 | 6 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2021 | 8.559 | 2.3 | 44 | Quality of life; Rectal cancer; Abdominoperineal resection; Sphincter preservation surgery; Sexual function; Urinary function; Oncological outcome | LOW ANTERIOR RESECTION; POSTOPERATIVE CHEMORADIOTHERAPY; NEOADJUVANT CHEMORADIOTHERAPY; INTERSPHINCTERIC RESECTION; RANDOMIZED-TRIAL; OPEN-LABEL; EXCISION; OUTCOMES | English | 2021 | 2021-01 | 10.1016/j.lanwpc.2020.100087 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
○ | ○ | Article | Development of γ-aminobutyric acid-, glycine-, and glutamate-immunopositive boutons on the rat genioglossal motoneurons | Detailed information about the development of excitatory and inhibitory synapses on the genioglossal (GG) motoneuron may help to understand the mechanism of fine control of GG motoneuron firing and the coordinated tongue movement during postnatal development. For this, we investigated the development of gamma-aminobutyric acid (GABA)-immunopositive (GABA +), glycine + (Gly +), and glutamate + (Glut +) axon terminals (boutons) on the somata of rat GG motoneurons at a postnatal day 2 (P2), P6 and P18 by retrograde labeling of GG motoneurons with horseradish peroxidase, electron microscopic postembedding immunogold staining with GABA, Gly, and Glut antisera, and quantitative analysis. The number of boutons per GG motoneuron somata and the mean length of bouton apposition, measures of bouton size and synaptic covering percentage, were significantly increased from P2/P6 to P18. The number and fraction of GABA + only boutons of all boutons decreased significantly, whereas those of Gly + only boutons increased significantly from P2/P6 to P18, suggesting developmental switch from GABAergic to glycinergic synaptic transmission. The fraction of mixed GABA +/Gly + boutons of all boutons was the highest among inhibitory bouton types throughout the postnatal development. The fractions of excitatory and inhibitory boutons of all boutons remained unchanged during postnatal development. These findings reveal a distinct developmental pattern of inhibitory synapses on the GG motoneurons different from that on spinal or trigeminal motoneurons, which may have an important role in the regulation of the precise and coordinated movements of the tongue during the maturation of the oral motor system. | Paik, Sang Kyoo; Yoshida, Atsushi; Bae, Yong Chul | Kyungpook Natl Univ, Dept Anat & Neurobiol, Sch Dent, 188-1,2 Ga, Daegu 700412, South Korea; Osaka Univ, Dept Oral Anat & Neurobiol, Grad Sch Dent, Osaka 5650871, Japan | 9335557600; 55757780066; 56377838800 | ycbae@knu.ac.kr; | BRAIN STRUCTURE & FUNCTION | BRAIN STRUCT FUNCT | 1863-2653 | 1863-2661 | 226 | 3 | SCIE | ANATOMY & MORPHOLOGY;NEUROSCIENCES | 2021 | 3.748 | 2.4 | 0.61 | 2025-07-30 | 5 | 5 | Hypoglossal motoneuron; Excitatory; Inhibitory; Presynaptic axon terminal; Development; Electron microscopy | Development; Electron microscopy; Excitatory; Hypoglossal motoneuron; Inhibitory; Presynaptic axon terminal | Animals; Dendrites; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microscopy, Electron; Motor Neurons; Neural Inhibition; Presynaptic Terminals; Rats, Sprague-Dawley; Synapses; Trigeminal Nuclei; 4 aminobutyric acid; glutamic acid; glycine receptor; horseradish peroxidase; pentobarbital; 4 aminobutyric acid; glutamic acid; animal cell; animal experiment; Article; controlled study; electron microscopy; firing rate; GABAergic system; GABAergic transmission; genioglossal motoneuron; immunogold staining; motor system; nerve ending; nonhuman; postnatal development; presynaptic nerve; priority journal; quantitative analysis; rat; spinal cord motoneuron; synaptic potential; synaptic transmission; tongue; trigeminal nerve; animal; dendrite; male; metabolism; motoneuron; nerve cell inhibition; nerve ending; physiology; procedures; Sprague Dawley rat; synapse; trigeminal nucleus; ultrastructure | English | 2021 | 2021-04 | 10.1007/s00429-021-02216-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | Direct measurement of surface adhesion between thin films of nanocellulose and urea-formaldehyde resin adhesives | When applying an adhesive to wood, the chemical heterogeneity of the wood cell walls makes it difficult to understand the contribution they make to the interfacial adhesion between the adhesive and the wood as the adhesion is a very complex physical and chemical phenomenon. This study, for the first time, directly measured the surface adhesion between cellulose, a major component of wood, and urea-formaldehyde (UF) resin adhesives. The adhesion between thin, smooth nanocellulose films, such as cellulose nanofibrils (CNFs), carboxymethylated nanofibrils (CM)-CNFs, and carboxylated cellulose nanocrystals (C-CNCs), and UF resins with two formaldehyde to urea (F/U) molar ratios of 1.0 and 1.6 was measured using two approaches: (1) direct measurement of the adhesion force between nanocellulose films and liquid droplets of the UF resins, and (2) calculation of the work of adhesion between films of the nanocelluloses and UF resins using the contact angle and the van Oss-Chaudhury-Good method. The results show that the total surface free energies, either between the different nanocelluloses or between the two UF resins are somewhat similar, indicating the similarity in their surface properties. However, the adhesion force and work of adhesion of 1.6 UF resins with different types of nanocellulose are higher than those of 1.0 UF resins, which shows that van der Waals forces are dominant in their molecular interactions. These results suggest that the adhesion between 1.6 UF resins and nanocellulose is stronger than that when 1.0 UF resins are used because the 1.6 UF resins have a more branched structure, smoother surface, and higher surface free energy. | Wibowo, Eko Setio; Park, Byung-Dae | Kyungpook Natl Univ, Dept Wood & Paper Sci, Daegu 41566, South Korea | Park, Byung-Dae/ABB-1934-2020; Wibowo, Eko/AAL-5888-2021 | 57214910272; 7402834820 | byungdae@knu.ac.kr; | CELLULOSE | CELLULOSE | 0969-0239 | 1572-882X | 28 | 13 | SCIE | MATERIALS SCIENCE, PAPER & WOOD;MATERIALS SCIENCE, TEXTILES;POLYMER SCIENCE | 2021 | 6.123 | 2.4 | 0.67 | 2025-07-30 | 11 | 15 | Nanocellulose; UF resins; Adhesion force; Work of adhesion; Surface free energy; Van der Waals force | CONTACT-ANGLE HYSTERESIS; CELLULOSE NANOFIBRILS; CRYSTALLINITY; POLYMER; LIGNIN; CARBOXYMETHYLATION; WETTABILITY; MORPHOLOGY; EMISSION; SMOOTH | Adhesion force; Nanocellulose; Surface free energy; UF resins; Van der Waals force; Work of adhesion | Adhesion; Adhesives; Cellulose Derivatives; Contact Angle; Formaldehyde; Adhesion; Adhesives; Cellulose; Cellulose derivatives; Cellulose films; Cellulose nanocrystals; Contact angle; Formaldehyde; Free energy; Metabolism; Molar ratio; Nanocellulose; Nanofibers; Resins; Thin films; Urea; Van der Waals forces; Wood; Branched structures; Cellulose nanofibrils (CNFs); Chemical heterogeneities; Chemical phenomenas; Interfacial adhesions; Nanocellulose films; Surface free energy; Total surface free energies; Urea formaldehyde resins | English | 2021 | 2021-09 | 10.1007/s10570-021-04088-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
○ | ○ | Article | Highly-porous uniformly-sized amidoxime-functionalized cellulose beads prepared by microfluidics with N-methylmorpholine N-oxide | Uniformly-sized porous cellulose beads functionalized with amidoxime groups were prepared for the first time using a microfluidic method with N-methylmorpholine N-oxide (NMMO) monohydrate as a cellulose solvent. The molten state cellulose dope in NMMO monohydrate (cell/NMMO dope) as a disperse phase and hot mineral oil as a continuous phase were used in a T-junction microfluidic chip to produce uniformly-sized cell/NMMO droplets. Coagulation of the molten state cell/NMMO droplet at high temperature and amidoxime functionalization could prepare the highly-porous spherical amidoxime-functionalized cellulose beads with a uniform fibrous open internal structure. The prepared amidoxime-functionalized cellulose beads showed excellent metal adsorption properties with a maximum adsorption capacity of similar to 80 mg g(-1) in the case of Cu2+/phthalate ions. The newly developed highly-porous cellulose beads can open many new applications with other proper functionalization at the reactive hydroxyl groups of the cellulose. ]GRAPHICS]. | Baek, Seung-Yeop; Park, Soo-Young | Kyungpook Natl Univ, Sch Appl Chem Engn, Polymer Nano Mat Lab, Daegu 41566, South Korea | park, soo-young/N-3170-2017 | 59802526000; 57194041850 | psy@knu.ac.kr; | CELLULOSE | CELLULOSE | 0969-0239 | 1572-882X | 28 | 9 | SCIE | MATERIALS SCIENCE, PAPER & WOOD;MATERIALS SCIENCE, TEXTILES;POLYMER SCIENCE | 2021 | 6.123 | 2.4 | 0.52 | 2025-07-30 | 8 | 8 | Cellulose; Microfluidics; N-methylmorpholine N-oxide; Amidoxime; Metal adsorption; Filter | POLY(AMIDOXIME) LIGAND; ADSORPTION; IONS; DERIVATIVES; KINETICS; REMOVAL; NMMO | Amidoxime; Cellulose; Filter; Metal adsorption; Microfluidics; N-methylmorpholine N-oxide | Adsorption; Beads; Capacity; Cellulose; Chips; Drops; High Temperature; Phases; Drops; Microfluidics; Adsorption capacities; Functionalizations; High temperature; Internal structure; Microfluidic chip; Microfluidic method; N methylmorpholine N oxide; New applications; Cellulose | English | 2021 | 2021-06 | 10.1007/s10570-021-03872-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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