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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Suicide risk prediction for Korean adolescents based on machine learning Traditional clinical risk assessment tools proved inadequate for reliably identifying individuals at high risk for suicidal behavior. As a result, machine learning (ML) techniques have become progressively incorporated into psychiatric care. This study evaluates the predictive capability of national survey data, which includes factors such as lifestyle behaviors and mental health indicators, in forecasting adolescent suicidal behavior. The predictive performance of six ML models-Logistic Regression (LR), Decision Tree (DT), Support Vector Machine (SVM), Gradient Boosting Machine (GBM), Extremely Randomized Trees (ET), and Distributed Random Forest (DRF)-was systematically compared. Employed SHapley Additive exPlanations (SHAP) values and Permutation Feature Importance (PFI) for interpretability analysis, and ultimately utilized interaction analysis to examine the complex interrelationships among key variables associated with suicide risk. Both the Expert Consultation Method (ECM) and Random Forest-Based Filter Feature Selection (RFFS) datasets revealed that the GBM model achieved the best results, with a predictive accuracy (ACC) of 88%, sensitivity (SENS) of 97%, specificity (SPEC) of 26%, positive predictive value (PPV) of 90%, negative predictive value (NPV) of 56%, and an area under the curve (AUC) of 83%. Feature importance analysis identified stress and depression as the most significant determinants of suicidal ideation and behavior in middle and high school students, respectively. Multivariate interaction effect analysis further revealed that, at higher levels of depression, lower anxiety levels were significantly correlated with a reduced probability of suicide risk. Additionally, a positive association between stress and anxiety was observed. Overall, the integration of advanced computational techniques with national survey data moderately enhances the accuracy of suicide risk prediction, providing a strong empirical foundation for early intervention in adolescent suicidal behavior. Wang, Haitao; Yuan, Han; Zhang, Yunong; Wang, Qixuan; Gao, Zeng; Zhao, Mujuan Kyungpook Natl Univ, Dept Phys Educ, Daegu 41566, South Korea; Sejong Univ, Dept Phys Educ, Seoul 05006, South Korea; Sungkyunkwan Univ, Dept Financial Technol, Seoul 05073, South Korea; Xiangtan Univ, Xiangtan, Peoples R China; Kyungpook Natl Univ, Dept Recreat & Sports, Sangju Campus, Daegu 41566, South Korea 59759369800; 58784951600; 59473276300; 59759157100; 59141458400; 59758931600 mujuanzhao@gmail.com; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 15 1 SCIE MULTIDISCIPLINARY SCIENCES 2024 3.9 18.1 0 2025-05-07 0 0 Suicide Risk; Adolescents; Machine Learning; Multidimensional Data; Prediction model IDEATION; BEHAVIORS; THOUGHTS; HEALTH; TIME Adolescents; Machine Learning; Multidimensional Data; Prediction model; Suicide Risk Adolescent; Depression; Female; Humans; Machine Learning; Male; Republic of Korea; Risk Assessment; Risk Factors; Suicidal Ideation; Suicide; Support Vector Machine; adolescent; depression; epidemiology; female; human; machine learning; male; procedures; psychology; risk assessment; risk factor; South Korea; suicidal ideation; suicide; support vector machine English 2025 2025-04-28 10.1038/s41598-025-99626-0 바로가기 바로가기 바로가기 바로가기
Article The neural basis of intuitive approximate number system in board game Go (Baduk) experts Studies have shown that newborns and nonhuman animals innately estimate quantities using the approximate number system (ANS), raising questions about whether the ANS is a precursor to advanced computational abilities or an independent cognitive function. Professional board game Go players, who can quickly judge territory sizes without explicit calculations, provide a unique insight into the ANS. Using fMRI, we investigated the neural correlates of the approximate number system in professional Go players. Results showed that during the difficult task, professional Go players exhibited significantly increased activity in the right cerebellum compared to the controls, while several parts of the cerebrum were activated during the easy task. The observed activation in the right cerebellum was inversely correlated with the number of years of training required to become professional players. The findings indicate that the ANS is either facilitated by training or reflects an inherent, exceptional ability in certain individuals, suggesting a cerebellar-based alternative to the computational role of the cerebral cortex. Lee, Taeyoung; Jo, Hang Joon; Kim, Minah; Kwon, Jun Soo Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea; Seoul Natl Univ, Med Res Ctr, Inst Human Behav Med, Seoul, South Korea; Grad Sch Biomed Sci & Engn, Dept Biomed Engn, Seoul, South Korea; Hanyang Univ, Dept Physiol, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Neuropsychiat, Seoul, South Korea; Hanyang Univ Hosp, Dept Psychiat, Seoul, South Korea; Hanyang Univ, Coll Med, Dept Psychiat, 222-1 Wangsimni Ro, Seoul 110744, South Korea JO, HANG/D-1775-2011 55731225400; 15080568500; 57191729747; 59867451000 kwonjs@snu.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 15 1 SCIE MULTIDISCIPLINARY SCIENCES 2024 3.9 18.1 0 2025-06-11 0 0 Approximate number system; Expert brain; Cerebellum; Game of Go (Baduk) MOTOR CONTROL; CEREBELLUM; BRAIN; COGNITION; SKILLS; ACTIVATION; EVOLUTION; LANGUAGE; FMRI Approximate number system; Cerebellum; Expert brain; Game of Go (Baduk) Adult; Brain Mapping; Cerebellum; Cognition; Female; Humans; Magnetic Resonance Imaging; Male; Young Adult; adult; aptitude; article; board game; brain cortex; cerebellum; cognition; controlled study; female; functional magnetic resonance imaging; game; human; human experiment; male; nerve cell; newborn; nonhuman; normal human; brain mapping; diagnostic imaging; nuclear magnetic resonance imaging; physiology; young adult English 2025 2025-05-12 10.1038/s41598-025-98605-9 바로가기 바로가기 바로가기 바로가기
Article Using structural equation modelling to reassess bias in judging the vault event in men’s artistic gymnastics In gymnastics competitions, the judges evaluate the performance of the gymnasts to determine the winners. Over the past few decades, cognitive psychology scholars have argued that judges in international gymnastics competitions may possess national biases and various forms of memory bias. This paper newly evaluates these biases using empirical data obtained from the men’s vault qualification event in the 51st FIG Artistic Gymnastics World Championships Liverpool – 2022. The data consisted of all of the Men’s Artistic Gymnastics (MAG) vault scores in the qualification round (N = 133), collected from seven execution panel judges representing Argentina, Colombia, Kazakhstan, Norway, the People’s Republic of China, the Republic of Korea, and Slovenia. These scores were analysed using the structural equation modelling (SEM) technique. The SEM results indicated good model fit, χ2 (14.404) / 12 = 0.83, SRMR = 0.031, CFI = 0.998, TLI = 0.996 and RMSEA = 0.039. Thus, the nationality of the judges was not a significant factor in predicting the gymnasts’ execution scores (β = -0.008, p = 0.297) and overall results. The individual skill level of the gymnasts, particularly the difficulty value of the vault element, was the most important predictor of the overall ranking in the qualification event (β = -63.757, p < 0.001) and of the probability of qualifying for the final (β = 0.226, p = 0.001). The findings of this study reveal no empirical evidence of bias in gymnastics judging at an international competition. In the MAG vault event, the gymnast’s skill level, especially the difficulty value of the element, is the most crucial factor in determining the ranking outcome of the event. The implications for research and theoretical development are discussed. © The Author(s) 2025. Fung, Sai-Fu; Han, Yoon-Soo; Mickevics, Arturs Department of Social and Behavioural Sciences, City University of Hong Kong, Tat Chee Avenue, Hong Kong; Department of Physical Education, Kyungpook National University, Deagu, South Korea, International Gymnastics Federation, Men’s Artistic Gymnastics Technical Committee, Lausanne, Switzerland; International Gymnastics Federation, Men’s Artistic Gymnastics Technical Committee, Lausanne, Switzerland 56810508100; 59970991500; 59971499200 sffung@cityu.edu.hk; Scientific Reports SCI REP-UK 2045-2322 2045-2322 15 1 SCIE MULTIDISCIPLINARY SCIENCES 2024 3.9 18.1 0 Gymnastics; Judge; Memory biases; National bias; Vault adult; article; China; cognitive psychology; Colombia; competition; controlled study; diagnosis; DNA transposon; female; gymnast; gymnastics; human; Kazakhstan; major clinical study; male; memory; memory bias; nationality; Norway; probability; Slovenia; South Korea English Final 2025 10.1038/s41598-025-05939-5 바로가기 바로가기 바로가기
Article A comparative analysis of older patients with chewing difficulties due to temporomandibular disorders and tooth loss Background/purpose: Chewing difficulty can contribute to psychological stress, which reduces the quality of life for older adults. The purpose of this study was to investigate and analyze the severity of masticatory discomfort, stress response, and sleep disturbance in older patients experiencing masticatory discomfort due to tooth loss or temporomandibular disorders (TMD), to find the further treatment direction for these patients. Materials and methods: A total of 392 patients aged 50 years and older with mastication difficulties were analyzed. Two group of patients, those seeking prosthetic treatment due to tooth loss (n = 193) and those who were referred due to TMD-related pain discomfort (n = 199), were identified. Numeric rating scale (NRS), stress response inventory (SRI), and insomnia severity index (ISI) were used as tools to measure patients' subjective chewing discomfort, stress response, and sleep status. Results: Chewing discomfort and age were found to be much higher in the prosthetic group than in the TMD group. The TMD group had significantly higher scores in five SRI parameters (tension, anger, depression, fatigue, and frustration) as well as total score and a higher percentage of clinical insomnia compared to prosthetic patients. Conclusion: Since the number of remaining teeth has a significant impact on the masticatory discomfort severity, restoring the occlusion through prosthodontic treatment is important to improve masticatory function. In patients with TMD, it is necessary to assess stress response and sleep quality, and a multidisciplinary treatment approach may be necessary to effectively address masticatory discomfort. 2025 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/). Jeon, Hye-Mi; Kim, So-Yeun; Ahn, Yong-Woo; Ok, Soo-Min; Jeong, Sung-Hee; Ju, Hye-Min Pusan Natl Univ Hosp, Dent Clin Ctr, Dept Oral Med, Busan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Prosthodont, Daegu, South Korea; Pusan Natl Univ, Dent & Life Sci Inst, Sch Dent, Dept Oral Med, Yangsan, South Korea; Pusan Natl Univ Dent Hosp, Dent Res Inst, Dept Oral Med, Yangsan, South Korea ; Ju, Hye-min/MTG-0872-2025 57195512995; 57190972249; 24176507600; 56367555400; 54418858100; 57210857734 jc2wma@pusan.ac.kr; JOURNAL OF DENTAL SCIENCES J DENT SCI 1991-7902 2213-8862 20 1 SCIE DENTISTRY, ORAL SURGERY & MEDICINE 2024 3.1 18.2 0 2025-05-07 0 0 Psychological stress; Temporomandibular; joint disorders; Tooth loss MASTICATORY ABILITY; GENDER-DIFFERENCE; OCCLUSAL SUPPORT; DENTAL STATUS; DEPRESSION; ASSOCIATION; INSOMNIA; SEVERITY; SLEEP; PAIN Chewing; Psychological stress; Temporomandibular joint disorders; Tooth loss English 2025 2025-01 10.1016/j.jds.2024.07.001 바로가기 바로가기 바로가기 바로가기
Article Fracture resistances of heat-treated nickel-titanium files used for minimally invasive instrumentation BackgroundThis study compared the torsional resistance, bending stiffness, and cyclic fatigue resistances of different heat-treated NiTi files for minimally invasive instrumentation. MethodsTruNatomy (TN) and EndoRoad (ER) file systems were compared with ProTaper Gold (PG). Torsional load, distortion angle, and bending stiffness were assessed using a custom device AEndoS, and toughness was calculated using the torsional data. Cyclic fatigue resistance was evaluated using another custom device (EndoC) with 45-degree curved canal in which file was rotated until fracture using dynamic pecking motion at 37 degrees C. One-way analysis of variance and Duncan's post-hoc comparison were conducted at a significance level of 95%. Scanning electron microscopy (SEM) analyzed fracture features and differential scanning calorimetry (DSC) analyzed phase transformation temperatures. ResultsER and TN showed significantly lower torsional strength than PG (p < 0.05). However, ER showed a significantly greater distortion angle and the highest toughness, followed by PG and TN (p < 0.05). Both ER and TN showed similar bending stiffness, which was lower bending stiffness than PG (p < 0.05). ER showed the highest cyclic fatigue resistance (p < 0.05). SEM revealed typical fracture features across all groups, with distinct milling grooves in PG and TN, not in ER. DSC indicated that PG and ER showed a peak of austenite (Ap) at temperatures higher than body temperature, 42 degrees C and 40 degrees C, respectively, while TN showed A p at 25 degrees C. ConclusionFiles for minimally invasive instrumentations typically exhibited high cyclic fatigue resistance but showed differences in the properties. The selection should depend on the root canal and tooth condition. Kang, Yoo Jung; Kwak, Sang Won; Ha, Jung-Hong; Gambarini, Gianluca; Kim, Hyeon-Cheol Pusan Natl Univ, Dent Res Inst, Dent & Life Sci Inst, Dept Conservat Dent,Sch Dent, Yangsan, South Korea; Kyungpook Natl Univ, Coll Dent, Dept Conservat Dent, Daegu, South Korea; Sapienza Univ Rome, Dept Oral & Maxillofacial Sci, I-00161 Rome, Italy; Pusan Natl Univ, Dent Res Inst, Sch Dent, Dept Conservat Dent, Geumo Ro 20, Yangsan 50612, Gyeongnam, South Korea ; Kim, Hyeon/AAQ-9057-2021 57907362000; 54787794900; 55549831900; 7005345776; 35746710200 endokwak@pusan.ac.kr; endoking@knu.ac.kr; gianluca.gambarini@uniroma1.it; golddent@pusan.ac.kr; BMC ORAL HEALTH BMC ORAL HEALTH 1472-6831 25 1 SCIE DENTISTRY, ORAL SURGERY & MEDICINE 2024 3.1 18.2 0 2025-05-07 1 1 Bending stiffness; Heat treatment; Minimal invasive; Torsional resistance; Cyclic fatigue CYCLIC FATIGUE RESISTANCE; ROTARY FILES; ACCESS; CAVITY; STIFFNESS; INCISORS Bending stiffness; Cyclic fatigue; Heat treatment; Minimal invasive; Torsional resistance Calorimetry, Differential Scanning; Dental Alloys; Dental Instruments; Dental Stress Analysis; Equipment Design; Equipment Failure; Flexural Strength; Hot Temperature; Humans; Materials Testing; Microscopy, Electron, Scanning; Nickel; Phase Transition; Pliability; Root Canal Preparation; Stress, Mechanical; Surface Properties; Titanium; Torsion, Mechanical; Austenite; dental alloy; nickel; titanium; titanium nickelide; chemistry; comparative study; dental device; dental procedure; device failure; devices; differential scanning calorimetry; equipment design; flexural strength; high temperature; human; materials testing; mechanical stress; mechanical torsion; phase transition; pliability; root canal preparation; scanning electron microscopy; surface property English 2025 2025-01-23 10.1186/s12903-025-05487-4 바로가기 바로가기 바로가기 바로가기
Review Haploid Production in Cannabis sativa: Recent Updates, Prospects, and Perspectives Cannabis sativa L. is a dioecious species known to produce over 1600 chemical constituents, including more than 180 cannabinoids classified into 11 structural groups. These bioactive compounds are predominantly synthesised in the glandular trichomes of female inflorescences. However, sex determination in C. sativa is influenced by both genetic and environmental factors, often leading to the development of male flowers on female plants. This unintended fertilisation reduces cannabinoid yield and increases genetic heterogeneity and challenges in medical cannabis production. Haploid and doubled haploid (DH) technologies offer a promising solution by rapidly generating homozygous lines from gametophytic (e.g., unpollinated ovaries and ovules) or sporophytic tissues (e.g., anthers and microspores) via in vitro culture or chromosome reduction during hybridisation. In land plants, the life cycle alternates between a diploid sporophyte and a haploid gametophyte generation, both capable of mitotic division to form multicellular bodies. A single genome regulates this phase transition and encodes the molecular, genetic, and epigenetic mechanisms that precisely control the developmental processes unique to each generation. While the application of haploid technology in C. sativa remains limited, through recent progress in haploid induction (HI) and CRISPR-based genome editing, the direct modification of haploid gametes or embryos enables the creation of null homozygous lines following chromosome doubling, improving genetic uniformity. Understanding the molecular mechanisms of spontaneous chromosome doubling may further facilitate the development of elite cannabis genotypes. Ultimately, enhancing the efficiency of DH production and optimising genome editing approaches could significantly increase the speed of genetic improvement and cultivar development in Cannabis sativa. Ahsan, S. M.; Injamum-Ul-Hoque, Md.; Howlader, Nayan Chandra; Rahman, Md. Mezanur; Rahman, Md Mahfuzur; Haque, Md Azizul; Choi, Hyong Woo Andong Natl Univ, Dept Plant Med, Andong 36729, South Korea; Gopalganj Sci & Technol Univ, Dept Agr, Gopalganj 8100, Bangladesh; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Bangladesh Agr Univ, Fac Agr, Dept Hort, Mymensingh 2202, Bangladesh; Texas Tech Univ, Inst Genom Crop Abiot Stress Tolerance, Dept Plant & Soil Sci, Lubbock, TX 79409 USA; Yeungnam Univ, Dept Biotechnol, Gyongsan 38541, South Korea; Andong Natl Univ, Inst Cannabis Biotechnol, Andong 36729, South Korea 7004038250; 58663974700; 59243019400; 57203277829; 57217464365; 58223031200; 14627068300 smvahsan@gmail.com; mdinjamum92@knu.ac.kr; nayanhowladar@gmail.com; mdmerahm@ttu.edu; mmahfuz.edu.bd@gmail.com; azizul@ynu.ac.kr; hwchoi@anu.ac.kr; BIOLOGY-BASEL BIOLOGY-BASEL 2079-7737 14 6 SCIE BIOLOGY 2024 3.5 18.2 0 0 Cannabis sativa; haploid production; pollen; egg cell; Thiadizuron; CRISPR/Cas9 SOMATIC EMBRYOGENESIS; ANTHER CULTURE; IN-VITRO; REPRODUCTION; INDUCTION; PLANTS Cannabis sativa; CRISPR/Cas9; egg cell; haploid production; pollen; Thiadizuron English 2025 2025-06-15 10.3390/biology14060701 바로가기 바로가기 바로가기 바로가기
Article Mucosal deposit after triamcinolone injection: a case report BackgroundOral ulcers exhibit diverse symptoms and etiologies. The treatment approach varies depending on the size and characteristics of the ulcer, typically starting with topical therapies such as steroid or antifungal mouth rinses. While most ulcers respond well to these localized treatments, some cases necessitate systemic interventions, including oral medications or intralesional injections.Case presentationA 59-year-old man with a one-month history of a persistent oral ulcer in the maxillary vestibule was diagnosed with major aphthous ulcer and treated with intralesional triamcinolone injection and corticosteroid gargle. The ulcer healed completely within two weeks, but a triamcinolone deposit remained asymptomatic and resolved spontaneously within a month. The patient experienced no discomfort and required no further intervention.ConclusionsWhile triamcinolone is a highly effective and rapid treatment for oral mucosal ulcers, caution is advised when treating ulcers above the alveolar bone. It is preferred to administer injections in the corresponding vestibular groove near the buccal mucosa, which has a rich blood supply, rather than above the alveolar bone. Otherwise, reducing the dosage or switching to a more easily absorbable corticosteroid, such as dexamethasone, may be carefully recommended. Kang, Kun-Hwa; Byun, Jin-Seok; Jung, Jae-Kwang; Kim, Ji Rak Kyungpook Natl Univ, Dept Oral Med, Dent Hosp, 2175 Dalgubeol Daero, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral Med, 2177 Dalgubeol Daero, Daegu 41940, South Korea 59739374400; 55430621800; 55970994400; 57207438323 jirak@knu.ac.kr; BMC ORAL HEALTH BMC ORAL HEALTH 1472-6831 25 1 SCIE DENTISTRY, ORAL SURGERY & MEDICINE 2024 3.1 18.2 0 2025-05-07 0 0 Intralesional injection; Oral ulcer; Triamcinolone acetonide ORAL LICHEN-PLANUS; ACETONIDE INJECTION; CORTICOSTEROIDS; EFFICACY Intralesional injection; Oral ulcer; Triamcinolone acetonide Glucocorticoids; Humans; Injections, Intralesional; Male; Middle Aged; Mouth Mucosa; Stomatitis, Aphthous; Triamcinolone; glucocorticoid; triamcinolone; aphthous stomatitis; case report; drug effect; drug therapy; human; intralesional drug administration; male; middle aged; mouth mucosa; pathology English 2025 2025-04-13 10.1186/s12903-025-05919-1 바로가기 바로가기 바로가기 바로가기
Article Proline Promotes Drought Tolerance in Maize Drought stress significantly affects maize (Zea mays L.) growth by disrupting vital physiological and biochemical processes. This study investigates the potential of proline supplementation to alleviate drought-induced stress in maize plants. The results show that proline supplementation enhanced shoot and root growth under normal conditions and alleviated drought-induced reductions in growth parameters. Under drought stress, proline increased shoot length by 40%, root length by 36%, shoot fresh weight by 97%, root fresh weight by 247%, shoot dry weight by 77%, and root dry weight by 154% compared to the untreated plants. While drought stress induced electrolyte leakage and reduced the relative water content (RWC) and leaf area, proline treatment mitigated these effects by improving membrane stability, water retention, and chlorophyll content. Moreover, proline supplementation reduced hydrogen peroxide (H2O2) and malondialdehyde (MDA) levels by 38% and 67%, respectively, in the drought-stressed plants compared to the untreated controls. It also enhanced catalase (CAT), peroxidase (POD), and superoxide dismutase (SOD) activities by 14%, 69%, and 144%, respectively, under drought stress, indicating a strengthened antioxidative defense. Proline also increased the protein content and improved N, P, and K retention by 30%, 40%, and 28%, respectively, in the drought-stressed plants, supporting metabolic and osmotic balance. Additionally, proline improved endogenous proline and sugar levels, facilitating osmotic adjustment and providing energy reserves. These findings suggest that proline supplementation effectively enhances maize resilience under drought stress, improving growth, reducing oxidative stress, and enhancing osmoprotection. Khan, Pirzada; Abdelbacki, Ashraf M. M.; Albaqami, Mohammed; Jan, Rahmatullah; Kim, Kyung-Min Chinese Acad Agr Sci, Biotechnol Res Inst, Beijing 100081, Peoples R China; King Saud Univ, Deanship Skill Dev, POB 2455, Riyadh 11451, Saudi Arabia; King Saud Univ, Coll Sci, Dept Bot & Microbiol, POB 2455, Riyadh 11451, Saudi Arabia; Kyungpook Natl Univ, Coastal Agr Res Inst, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea Jan, Rahmatullah/AIC-3439-2022; Abdelbacki, Ashraf/ABF-3628-2021; Albaqami, Mohammed/IYS-5838-2023; Kim, Kyung-Min Kim/C-7007-2014 57747802700; 35723565200; 57200223330; 57201981969; 34868260300 pirzada_111@yahoo.com; aabdelbacki@ksu.edu.sa; mmbaqami@ksu.edu.sa; rahmat2021@knu.ac.kr; kkm@knu.ac.kr; BIOLOGY-BASEL BIOLOGY-BASEL 2079-7737 14 1 SCIE BIOLOGY 2024 3.5 18.2 0 2025-05-07 3 4 drought stress; proline supplementation; oxidative stress; antioxidant defense; osmoprotection SALT-STRESS; EXOGENOUS PROLINE; GLYCINE BETAINE; WATER-DEFICIT; GROWTH; CULTIVARS; ACCUMULATION; INHIBITION; RECOVERY; RICE antioxidant defense; drought stress; osmoprotection; oxidative stress; proline supplementation English 2025 2025-01 10.3390/biology14010041 바로가기 바로가기 바로가기 바로가기
Article Glucocorticoid-Dependent Retinal Degeneration and Vision Impairment in Mice Susceptible to Prenatal Stress-Induced Behavioral Abnormalities Chronic exposure to prenatal stress can impair neurogenesis and lead to irreversible cognitive and neuropsychiatric abnormalities in offspring. The retina is part of the nervous system; however, the impacts of prenatal stress on retinal neurogenesis and visual function remain unclear. This study examined how elevated prenatal glucocorticoid levels differentially affect retinal development in the offspring of pregnant mice exposed to chronic unpredictable mild stress (CUMS). Offspring were classified into control, stress-resilient, and stress-susceptible groups based on behavioral tests assessing spatial memory and depression-like behaviors. The stress-susceptible group exhibited significantly altered synaptogenesis, reduced ganglion cell development, decreased retinal thickness, and visiual impairment. These mice also showed a pervasive transformation of retinal astrocytes into a proinflammatory A1-like reactive state, evidenced by increased GFAP and decreased STAT3 expression levels. This astrocyte phenotype shift coincided with disruptions in neurogenesis and synaptic formation. Furthermore, prenatal exposure to exogenous corticosterone confirmed that the effects of prenatal stress are mediated by glucocorticoid-induced retinal neurodegeneration. Our findings suggest that elevated prenatal glucocorticoid levels trigger a series of neurodevelopmental disturbances leading to retinal neurodegeneration and vision impairment. This research highlights the impact of prenatal stress on retinal development and visual health, suggesting new avenues for understanding and potentially mitigating the negative effects of early-life stress on neurodevelopment. © The Author(s) 2024. Ryu, Min-Ok; Jung, Ji-Youl; Suh, Han Na; Lee, Chung-Young; Kim, Myung-Chul; Oh, Ji Young; Song, Woo-Jin; Ahn, Changhwan; Yang, Yeseul; Choi, Gee Euhn Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea; College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, 63243, South Korea; Center for Translational Toxicologic Research, Korea Institute of Toxicology, 30 Baekhak1-gil, Jeonbukdo, Jeongup, 56212, South Korea; Department of Microbiology, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea, Untreatable Infectious Disease Institute, Kyungpook National University, Daegu, 41944, South Korea; Veterinary Laboratory Medicine, Clinical Pathology, College of Veterinary Medicine, Jeju National University, Jeju, 63243, South Korea, Research Institute of Veterinary Medicine, College of Veterinary Medicine, Jeju National University, Jeju, 63243, South Korea; Division of Intractable Disease Research, Korea Institute of Health, Osong, Cheongju, 28106, South Korea; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Jeju National University, Jeju, 63243, South Korea; Laboratory of Veterinary Physiology, College of Veterinary Medicine, Jeju National University, Jeju, 63243, South Korea; Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea; Laboratory of Veterinary Biochemistry, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, 63243, South Korea, Interdisciplinary Graduate Program in Advanced Convergence Technology & Science, Jeju National University, Jeju, 63243, South Korea 56730044500; 23469900900; 25628733900; 57195422071; 58416532000; 59483053900; 56959697200; 57191567568; 57218495436; 56668317300 choige@jejunu.ac.kr; Cellular and Molecular Neurobiology CELL MOL NEUROBIOL 0272-4340 1573-6830 45 1 SCIE CELL BIOLOGY;NEUROSCIENCES 2024 4.8 18.3 0 2025-05-07 0 Astrocyte activation; Glucocorticoid; Hypothalamic–Pituitary–Adrenal axis; Prenatal stress; Resilience; Retinal neurodevelopment Animals; Astrocytes; Behavior, Animal; Female; Glucocorticoids; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Retina; Retinal Degeneration; Stress, Psychological; Vision Disorders; corticosterone; glial fibrillary acidic protein; STAT3 protein; glucocorticoid; animal experiment; animal model; animal tissue; Article; astrocyte; behavior assessment; cell count; chronic unpredictable stress; controlled study; corticosterone blood level; depression; disease predisposition; female; maternal behavior; mouse; nerve cell differentiation; nerve degeneration; nervous system development; nonhuman; phenotype; prenatal exposure; prenatal period; prenatal stress; progeny; protein expression level; psychological resilience; retina degeneration; retina development; retinal thickness; spatial memory; synaptogenesis; visual impairment; animal; animal behavior; C57BL mouse; complication; drug effect; etiology; male; mental stress; metabolism; pathology; pregnancy; prenatal exposure delayed effect; retina; visual disorder English Final 2025 10.1007/s10571-024-01525-x 바로가기 바로가기 바로가기
Article Efficacy and safety of safinamide in Parkinson's disease patients with motor fluctuations without levodopa dosage escalation over 18 weeks: KEEP study This multicentre, prospective, single-arm study evaluated safinamide as add-on therapy to levodopa in Korean patients with Parkinson's disease (PD) with motor fluctuations with >= 1.5 h of "off" time daily, who took levodopa >= 3 times/day (n = 199). Baseline levodopa and dopamine agonist doses were maintained without escalation during the 18-week treatment period. Participants received safinamide 50 mg/day for 2 weeks and 100 mg/day thereafter. PD diaries and questionnaires (Parkinson's Disease Questionnaire, PDQ-39; Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale, MDS-UPDRS part 3 and part 4; King's Parkinson's Disease Pain Scale, KPPS; Mini-Mental State Examination, MMSE) were assessed at baseline and at week 18. Treatment-emergent adverse events (TEAEs) were recorded. Mean disease duration was 6.6 years, and mean levodopa equivalent daily dose was 721.1 mg/day. At week 18, significant improvements from baseline were seen for the co-primary endpoints, mean daily "off" time (- 1.3 +/- 2.4 h, p < 0.001) and quality of life (QoL) based on PDQ-39 summary index (- 2.7 +/- 10.3, p < 0.001), Moreover, significant improvements were seen in motor symptoms and motor complications (MDS-UPDRS part 3 and 4), daily "on" time without dyskinesia (all p < 0.001) and pain (KPPS; p = 0.013). TEAEs occurred in 40.2% of patients, with most being mild in severity. In conclusion, safinamide at a dosage of 100 mg/day significantly improved motor symptoms, QoL, and pain, and demonstrated a favourable safety profile without levodopa dosage escalation during the 18-week treatment period in Korean patients with PD. Oh, Eungseok; Cheon, Sang-Myeong; Cho, Jin Whan; Sung, Young Hee; Kim, Joong-Seok; Shin, Hae-Won; Kim, Jong-Min; Park, Mee Young; Kwon, Do-Young; Il, Hyeo Ma; Park, Jeong-Ho; Koh, Seong-Beom; Choi, Seong-Min; Park, Jinse; Lee, Phil Hyu; Ahn, Tae-Beom; Kim, Sang Jin; Lyoo, Chul Hyoung; Lee, Ho-Won; Kim, Jieun; Lee, Yoona; Baik, Jong Sam Chungnam Natl Univ, Coll Med & Hosp, Dept Neurol, Daejeon 301721, South Korea; Dong A Univ, Sch Med, Dept Neurol, Busan 602705, South Korea; Sungkyunkwan Univ, Sch Med, Sch Med, Dept Neurol, Seoul, South Korea; Gachon Univ, Coll Med, Gil Med Ctr, Dept Neurol, Incheon, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Neurol, Seoul 150713, South Korea; Chung Ang Univ Hosp, Dept Neurol, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Neurol, Seongnam, South Korea; Yeungnam Univ, Coll Med, Dept Neurol, Daegu, South Korea; Korea Univ, Ansan Hosp, Dept Neurol, Coll Med, Ansan, South Korea; Hallym Univ, Sacred Heart Hosp, Hallym Univ Sacred Heart Hosp, Dept Neurol, Anyang, South Korea; Soonchunhyang Univ, Bucheon Hosp, Coll Med, Dept Neurosurg, Bucheon Si, Gyeonggi Do, South Korea; Korea Univ, Guro Hosp, Dept Neurol, Guro Hosp, Seoul, South Korea; Chonnam Natl Univ, Chonnam Natl Univ Hosp, Med Sch, Dept Neurol, Gwangju, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Neurol, Busan, South Korea; Yonsei Univ, Coll Med, Dept Neurol, Seoul, South Korea; Kyung Hee Univ, Kyung Hee Univ Hosp, Kyung Hee Univ Hosp, Dept Neurol, Seoul, South Korea; Inje Univ, Coll Med, Busan Paik Hosp, Dept Neurol, Busan 614110, South Korea; Yonsei Univ, Coll Med, Gangnam Severance Hosp, Dept Neurol, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurol, Daegu 700422, South Korea; Eisai Korea Inc, Med Dept, Seoul, South Korea; Inje Univ, Sanggye Paik Hosp, Dept Pathol, Seoul, South Korea Lee, Ho Won/AAE-7526-2022; Kim, Yong Joon/IQS-7291-2023; Ahn, Tae-Beom/AAG-1309-2021; Lee, Jun-Hyuk/KOC-2534-2024; Oh, Eungseok/AAL-8935-2020 55833749700; 24329388300; 35084917900; 35278917000; 56271060800; 35314117600; 59640412000; 55361793300; 35574061200; 27467447200; 57202928261; 59308187300; 7408121966; 54938807200; 35201338900; 24340610100; 57189019510; 6505826405; 35337240700; 57941209000; 59410342100; 7006635133 jsbaik@paik.ac.kr; JOURNAL OF NEURAL TRANSMISSION J NEURAL TRANSM 0300-9564 1435-1463 132 3 SCIE CLINICAL NEUROLOGY;NEUROSCIENCES 2024 4 18.4 0 2025-05-07 1 1 Safinamide; Motor fluctuation; PDQ-39; QoL; Pain; Korea MINI-MENTAL-STATE; ADD-ON; DOUBLE-BLIND; THERAPY; ADJUNCT; RASAGILINE; TRIAL; PAIN Korea; Motor fluctuation; Pain; PDQ-39; QoL; Safinamide Aged; Alanine; Antiparkinson Agents; Benzylamines; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prospective Studies; Treatment Outcome; amantadine; antiparkinson agent; cholinergic receptor blocking agent; dopamine receptor stimulating agent; levodopa; safinamide; alanine; antiparkinson agent; benzylamine derivative; levodopa; safinamide; add on therapy; adult; Article; controlled study; coronavirus disease 2019; decreased appetite; disease duration; disease severity; dizziness; drug efficacy; drug overdose; drug safety; drug tolerability; drug withdrawal; dyskinesia; female; human; King Parkinson disease Pain scale; Korean (people); major clinical study; male; MDS-Unified Parkinson Disease Rating Scale; middle aged; Mini Mental State Examination; motor dysfunction; motor performance; multicenter study; nausea; pain; Parkinson disease; phase 4 clinical trial; Unified Parkinson Disease Rating Scale; vomiting; aged; clinical trial; combination drug therapy; drug therapy; Parkinson disease; prospective study; treatment outcome English 2025 2025-03 10.1007/s00702-024-02851-6 바로가기 바로가기 바로가기 바로가기
Article Electrically and environmentally stable nitric acid-assisted SnO2 films for the active channel layer of thin-film transistors Electrically and environmentally stable SnO2 thin-film transistors (TFTs) were fabricated with nitric acid (HNO3)-added liquid precursors using a low-temperature sol-gel process. The structural, chemical, optical, and electrical properties were investigated. The HNO3-added precursors resulted in the formation of high-density and amorphous-phase SnO2 films at 300 degrees C. The added HNO3 boosted the oxidation and sol-gel processes, successfully producing SnO2 films with SnON, fewer defects, and higher quality than pure SnO2 films. The formation of the high-density, fewer defect and high quality SnO2 with SnON resulted in significantly enhanced field-effect mobility. The HNO3 precursor-based TFTs exhibited robustness to external continuous positive and negative biases while maintaining environmental stability by inhibiting the chemical reaction of H2O absorption on the SnO2 surface. Compared to the pure SnO2-based TFTs, the SnO2 TFTs fabricated with HNO3-added liquid-phase precursors exhibited a twenty-fold higher field-effect mobility in the saturation regime of about 6.64 cm2/Vs, as well as good stability with negligible parameter variations and good environmental stability for up to two months. These findings are useful for forming electrically and environmentally stable metal oxide layers at relatively low temperatures for many metal oxide-based applications, such as TFTs, resistive random access memory and transparent electrodes for devices and solar cells. Cho, Yoonjin; Lee, Sangwoo; Heo, Seongwon; Choi, Suhyeon; Bae, Jin-Hyuk; Kang, In-Man; Kim, Kwangeun; Lee, Won-Yong; Jang, Jaewon Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Korea Aerosp Univ, Sch Elect & Informat Engn, Goyang 10540, South Korea; Kyungpook Natl Univ, Inst Elect Technol, Daegu 41566, South Korea 58567567900; 58567753300; 58960360300; 59484230700; 35326180700; 7203062678; 36004977500; 57209527128; 57194107504 yongsz@knu.ac.kr; j1jang@knu.ac.kr; MATERIALS TODAY ADVANCES MATER TODAY ADV 2590-0498 26 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY 2024 8 18.4 0 2025-05-07 0 0 Sol-gel; Bias stability; Oxygen vacancy; Thin-film transistors; SnON; SnO2 OXIDE SEMICONDUCTORS; TEMPERATURE; PERFORMANCE; DEVICES; OXYGEN; GLASS Bias stability; Oxygen vacancy; SnO<sub>2</sub>; SnON; Sol–gel; Thin-film transistors Defect density; Doping (additives); Hydrolysis; Oxygen; Photoionization; Photolysis; Pyrolysis; Sol-gel process; Active channel layers; Bias stability; C. thin film transistor (TFT); Environmental stability; Gel process; High quality; HNO 3; Lows-temperatures; SnO 2; Sol'gel; Amorphous films English 2025 2025-03 10.1016/j.mtadv.2025.100575 바로가기 바로가기 바로가기 바로가기
Article Material engineering to enhance reliability in 3D NAND flash memory Recent advancements in 3D NAND flash memory are driven by the need for higher storage density and faster data access speed, particularly to support emerging applications, such as artificial intelligence and memory- centric computing. As 3D NAND flash technology evolves, various technical problems related to process complexity have surfaced, such as those related to reliability. In this review, we focus on the individual storage unit known as a "cell device"and the reliability issues that arise with increasing memory density in 3D NAND flash. Attempts to address these challenges are outlined, focusing on the ONOP layers (tunneling/ trap/blocking/channel) materials that significantly impact reliability. However, the materials currently utilized for ONOP layers are faced with physical property limitations, necessitating the introduction of novel materials and processes for each ONOP layer. Kim, Ki Han; Kim, Namju; Kim, Yeong Kwon; Kim, Hee Seung; Oh, Han Byeol; Kim, Chae Eun; Shin, Hyeun Woo; Kim, Myeong Gi; Choi, Won Jun; Jang, Byung Chul Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Semicond Sci, 80 Daehak Ro, Daegu 41566, South Korea Jang, Byung Chul/GYV-0656-2022 58170931700; 58119785900; 58120005900; 59560125200; 59559917800; 57200245142; 59559119300; 59560125300; 59251189900; 9238827900 bc.jang@knu.ac.kr; DEVICE DEVICE 2666-9986 3 2 ESCI MATERIALS SCIENCE, MULTIDISCIPLINARY 2024 8 18.4 0 2025-05-07 0 0 TUNNEL BARRIER; CHARGE; CHANNEL; DEVICE; GATE; LAYER; OXIDE 3D NAND flash; cell device; charge-trap flash; DTI-2: Explore; reliability English 2025 2025-02-21 10.1016/j.device.2024.100682 바로가기 바로가기 바로가기 바로가기
Review Selection of intraoperative fluid for kidney transplantation The kidney, the most frequently transplanted organ, represents the optimal treatment for end-stage renal disease. Transplanted kidneys are highly vulnerable to perioperative injuries such as hypotension and hypovolemia, which can be influenced by perioperative fluid management. Postoperatively, delayed graft function increases the risk of graft failure. Although adequate volume administration can reduce delayed graft function, the type of intraoperative fluid most likely to benefit and support graft function remains unclear. Traditionally, crystalloids have been the primary choice for fluid management during kidney transplantation. Amongthese, 0.9% sodium chloride is the most commonly used, as its potassium-free composition minimizes the risk of hyperkalemia in patients with end-stage renal disease. Albumin is not routinely used, whereas synthetic colloids are discouraged owing to their nephrotoxicity. To date, 0.9% sodium chloride has demonstrated fewer advantages compared with balanced crystalloids, particularly regarding acid-base homeostasis, electrolyte balance, and delayed graft function. This review aims to examine the existing evidence on the effect of crystalloids and colloids on postoperative graft function and to recommend an appropriate fluid regimen, including balanced crystalloids, for kidney transplantation. Lee, Jeong Eun; Jung, Hoon Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Anesthesiol & Pain Med, Daegu, South Korea 57224846206; 55967121200 wing2392@naver.com; ANESTHESIA AND PAIN MEDICINE ANESTH PAIN MED 1975-5171 2383-7977 20 1 ESCI ANESTHESIOLOGY 2024 3.2 18.4 0 2025-05-07 0 0 Albumins; Crystalloid solutions; Delayed graft function; Fluid therapy; Kidney transplantation; Perioperative fluid management DELAYED GRAFT FUNCTION; LACTATED RINGERS SOLUTION; ACID-BASE-BALANCE; RENAL BLOOD-FLOW; HYDROXYETHYL STARCH; 0.9-PERCENT SALINE; HYPERCHLOREMIC ACIDOSIS; HUMAN ALBUMIN; SURVIVAL; IMPACT Albumins; Crystalloid solutions; Delayed graft function; Fluid therapy; Kidney transplantation; Perioperative fluid management English 2025 2025-01 10.17085/apm.24180 바로가기 바로가기 바로가기 바로가기
Article Bar ages derived for the first time in nearby galaxies Insights into secular evolution from the TIMER sample Once galaxies settle their discs and become self-gravitating, stellar bars can form, driving the subsequent evolution of their host galaxy. Determining the ages of bars can therefore shed light on the epoch of the onset of secular evolution. For this work we applied the first broadly applicable methodology to derive bar ages to a sample of 20 nearby galaxies. The method is based on the co-eval build-up of nuclear structures and bars, and involves using integral field spectroscopic (IFS) data from the Multi Unit Spectroscopic Explorer (MUSE) instrument on the Very Large Telescope to disentangle the star formation history of the nuclear disc from the background population. This allows us to derive the formation epoch of the nuclear disc, and thus of the bar. We estimated the bar formation epoch of nearby galaxies, mostly from the TIMER survey, and have created the largest sample of galaxies with known bar ages to date. We find bar formation epochs varying between 1 and 13 Gyr ago, illustrating how disc-settling and bar formation are processes that first took place in the early Universe and are still taking place in some galaxies. We infer the bar fraction over cosmological time with our sample, finding remarkable agreement with that obtained from direct studies of galaxies at high redshifts. Additionally, for the first time, we were able to investigate secular evolution processes taking into account the ages of bars. Our results agree with the scenario in which bars aid the quenching of the host galaxy; galaxies that host older bars tend to be more quenched. We also find that older bars tend to be longer and stronger, and to host larger nuclear discs. Furthermore, we find evidence that the nuclear disc stellar mass builds up over time. On the other hand, we find no evidence that downsizing plays a role in bar formation since we find that bar age is independent of galaxy stellar mass. With the means to estimate bar ages, we can begin to understand better when and how bars shape the observed properties of disc galaxies. de Sa-Freitas, Camila; Gadotti, Dimitri A.; Fragkoudi, Francesca; Coelho, Paula; de Lorenzo-Caceres, Adriana; Falcon-Barroso, Jesus; Sanchez-Blazquez, Patricia; Kim, Taehyun; Mendez-Abreu, Jairo; Neumann, Justus; Querejeta, Miguel; van de Ven, Glenn European Southern Observ, Alonso Cordova 3107, Vitacura, Chile; Univ Durham, Ctr Extragalact Astron, Dept Phys, South Rd, Durham DH1 3LE, England; Univ Durham, Inst Comp Cosmol, Dept Phys, South Rd, Durham DH1 3LE, England; Univ Sao Paulo, Inst Astron Geofis & Ciencias Atmosfer, Rua Matao 1226, BR-05508090 Sao Paulo, SP, Brazil; Univ La Laguna, Dept Astrofis, Dept Edafol & Geol, Avda Astrofis Francisco Sanchez S-N, E-38206 San Cristobal la Laguna, Tenerife, Spain; Inst Astrofis Canarias, C Via Lactea S-N, E-38205 San Cristobal la Laguna, Tenerife, Spain; Univ Complutense Madrid, Inst Fis Particulas & Cosmos IPARCOS, Madrid 28040, Spain; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea; Max Planck Inst Astron, Konigstuhl 17, D-69117 Heidelberg, Germany; Observ Astron Nacl IGN, C Alfonso XII 3, E-28014 Madrid, Spain; Univ Vienna, Dept Astrophys, Turkenschanzstr 17, A-1180 Vienna, Austria Falcon-Barroso, Jesus/AAD-9660-2019; Querejeta, Miguel/KVY-3638-2024; Sanchez-Blazquez, Patricia/IYS-6088-2023; van de Ven, Glenn/R-5189-2019 57211524578; 55887354100; 55062198600; 23011441600; 23088009300; 6602632408; 16319840900; 57050549000; 23051261000; 56514665700; 35424450700; 18038742400 camila.desafreitas@eso.org; ASTRONOMY & ASTROPHYSICS ASTRON ASTROPHYS 0004-6361 1432-0746 698 SCIE ASTRONOMY & ASTROPHYSICS 2024 5.8 18.5 0 2025-06-11 0 1 galaxies: bulges; galaxies: evolution; galaxies: kinematics and dynamics; galaxies: star formation; galaxies: stellar content; galaxies: structure 2-PHASE FORMATION HISTORY; EMISSION-LINE KINEMATICS; SDSS-IV MANGA; STAR-FORMATION; STELLAR STRUCTURE; SPITZER SURVEY; DISC GALAXIES; BILLION YEARS; ILLUSTRISTNG SIMULATIONS; COSMIC EVOLUTION galaxies: bulges; galaxies: evolution; galaxies: kinematics and dynamics; galaxies: star formation; galaxies: stellar content; galaxies: structure Dark energy; Dark Matter; Planets; Galaxies: Kinematics and dynamics; Galaxies: star formation; Galaxies:structure; Galaxy evolution; Galaxy:bulge; Galaxy:stellar content; Host galaxies; Secular evolution; Stellar mass; Stellars; Moon English 2025 2025-05-28 10.1051/0004-6361/202453367 바로가기 바로가기 바로가기 바로가기
Article Characteristics and Three-Dimensional Printability of Ginseng Starch Modified Using Acetylation, Heat-Moisture Treatment, and Citric Acid Hydrolysis We investigated whether ginseng starch is a suitable material for 3D printing. Native ginseng starch (NGS) exhibited poor extrusion performance when printed into a star-shaped structure. Although NGS cubes exhibited a low coefficient of variation (CV, < 5%), stacking led to slight structural collapse, resulting in a considerably reduced height than intended. To enhance the printing accuracy, the NGS was modified by acetylation (ACT), citric acid hydrolysis (CA), and heat-moisture treatment (HMT). The CV of samples printed using modified starch was lower than that of NGS, but the star-shaped structures printed with CA and ACT still exhibited low quality. In contrast, the HMT modification produced star-shaped structures with clear boundaries and the lowest CV in cube-shaped structures. Furthermore, the hardness of HMT-treated starch was higher than that of NGS, whereas ACT and CA modifications resulted in reduced hardness. These findings suggest that HMT is an effective modification method for enhancing 3D printing performance and controlling the textural properties of ginseng starch. Park, Jong-Jin; Kim, Jiyoon; Yun, Dae-Yong; Park, Seul-Ki; Cho, Jeong-Seok; Lee, Gyuseok; Choi, Jeong-Hee; Park, Kee-Jai; Moon, Kwang-Deog; Lim, Jeong-Ho Korea Food Res Inst, Food Safety & Distribut Res Grp, Wanju 55365, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, 80 Daehak Ro, Daegu 41566, South Korea; Korea Food Res Inst, Smart Food Mfg Project Grp, Wanju 55365, South Korea Park, Jongjin/AAL-3484-2021 58602432200; 57208110209; 57190400788; 57200227486; 56310090800; 55240240400; 57094285000; 7408066646; 55999192900; 36989648700 jhlim@kfri.re.kr; FOOD AND BIOPROCESS TECHNOLOGY FOOD BIOPROCESS TECH 1935-5130 1935-5149 18 4 SCIE FOOD SCIENCE & TECHNOLOGY 2024 5.8 18.5 0 2025-05-07 0 0 Ginseng Starch; 3D Printing; Starch Modification; Acetylation; Heat-Moisture Treatment; Citric Acid Hydrolysis SWEET-POTATO STARCH; IN-VITRO DIGESTIBILITY; PHYSICOCHEMICAL PROPERTIES; RHEOLOGICAL PROPERTIES; AMYLOSE; SPECTROSCOPY; FLOUR 3D Printing; Acetylation; Citric Acid Hydrolysis; Ginseng Starch; Heat-Moisture Treatment; Starch Modification Acetylation; Brinell Hardness; Citric acid; Moisture control; Rockwell hardness; 3-D printing; 3D-printing; Acid hydrolysis; Citric acid hydrolysis; Coefficients of variations; Ginseng starch; Heat-moisture treatments; Shaped structures; Star-shaped; Starch modification; Starch English 2025 2025-04 10.1007/s11947-024-03715-3 바로가기 바로가기 바로가기 바로가기
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