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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI ⓘ FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
○ ○ Article ⓘ Comparing factors affecting dental-implant loss between age groups: A retrospective cohort study ⓘ Background There is a growing interest in factors leading to implant failure in older people as the population aged 65 years or older continues to expand. Purpose We sought to identify differences of results in the implant survival rate and the influence of certain factors on implant failure in the older (>= 65 years) and younger (<65 years) patients. Materials and Methods Patients who underwent their first dental-implant surgery between July 2008 and June 2018 were included. Data on age, sex, smoking habits, medical conditions, implant location, implant size, and the presence and type of bone graft and membrane were collected and analyzed according to age group. Moreover, cumulative survival rates of implants (by Kaplan-Meier analysis) and hazard ratios (HR) of each factor (using Cox regression analysis with shared frailty) in each group were assessed and results compared between groups. Results A total of 628 implants in 308 patients and 1904 implants in 987 patients in the older and younger groups, respectively, were assessed, with failure rates of 3.9% and 3.4%. Per Kaplan-Meier analysis, the 11-year patient-level cumulative survival rate of implant treatment was 95.3% (95% CI: 0.91-0.97) in the older and 93.9% (95% CI: 0.88-0.97) in the younger group. The HR for implant failure of the variables, except diameter of dental implants, were not statistically significant in both groups. Conclusion The outcomes of implant treatment were not considerably different between the age groups. ⓘ Boboeva, Obida; Kwon, Tae-Geon; Kim, Jin-Wook; Lee, Sung-Tak; Choi, So-Young ⓘ Kyungpook Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, 2177 Dalgubeol Daero, Daegu 41940, South Korea ⓘ ⓘ 57220642750; 35205433300; 55862646000; 55931708300; 57202918688 ⓘ dentalchoi@knu.ac.kr; ⓘ CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH ⓘ CLIN IMPLANT DENT R ⓘ 1523-0899 1708-8208 23 2 SCIE DENTISTRY, ORAL SURGERY & MEDICINE ⓘ 2021 4.259 16.9 0.94 2025-07-30 ⓘ 6 7 dental implants; implant failure; older patients; survival rate ⓘ SURVIVAL ANALYSIS; OVERDENTURES; POPULATION; OLDER ⓘ dental implants; implant failure; older patients; survival rate ⓘ Age Factors; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Dental Implants; Dental Restoration Failure; Follow-Up Studies; Humans; Proportional Hazards Models; Retrospective Studies; adverse device effect; adverse event; age; aged; dental restoration; follow up; human; proportional hazards model; retrospective study; tooth implant; tooth implantation; very elderly ⓘ English 2021 2021-04 10.1111/cid.12967 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Evaluation of ocular surface disease in elderly patients with glaucoma: expression of matrix metalloproteinase-9 in tears ⓘ Purpose To evaluate the symptoms and signs of ocular surface disease (OSD) and tear-film matrix metalloproteinase-9 (MMP-9) overexpression using point-of-care testing (InflammaDry test) in patients with primary open-angle glaucoma (POAG). Methods This prospective, case-control study included 67 patients diagnosed with POAG and 47 healthy control subjects. The OSD assessment included Schirmer-I test, the Oxford corneal stain scale, tear breakup time (TBUT), and the five-item dry eye questionnaire (DEQ-5). Measurement of extracellular MMP-9 level was performed using the InflammaDry test. The OSD parameters and MMP-9 expression levels were compared between the POAG group and the control group. Additional subgroup analysis in POAG group was performed according to number of topical glaucoma medications (Bottle 1, 2, or 3 medications). Results There were significant differences between the control and POAG groups for all OSD parameters. MMP-9 overexpression was observed in 71.6% of POAG group, whereas only 31.9% of control group showed MMP-9 overexpression. The subgroup analysis revealed thatDEQ-5, Oxford stain score, Schirmer-I, and MMP-9 overexpression demonstrated no significant difference among the three groups. Abnormal TBUT (<= 5 s) was observed in 37.5%, 59.1%, and 76.2% for each subgroup according to number of bottles (1, 2, and 3), and strong MMP-9 overexpression were also detected in 25.0%, 40.9%, and 61.9%, respectively (P = 0.032,P = 0.043). Conclusions The use of preservative-containing medications may affect the ocular surface in patients with POAG. Graded measurement of tear-film MMP-9 could provide more information on OSD and might be a more useful marker for inflammation than then conventional results obtained by using an MMP-9 kit. ⓘ Kim, Dai Woo; Seo, Je Hyun; Lim, Su-Ho ⓘ Kyungpook Natl Univ Hosp, Dept Ophthalmol, Daegu, South Korea; Vet Hlth Serv Med Ctr, Vet Med Res Inst, Seoul, South Korea; Daegu Vet Hlth Serv Med Ctr, Dept Ophthalmol, 60 Wolgok Ro, Daegu 42835, South Korea; Yeungnam Univ, Dept Ophthalmol, Coll Med, Daegu, South Korea ⓘ Lim, Su-Ho/AAE-4344-2019; Seo, Je Hyun/AAR-6332-2020; LIM, SU-HO/AAE-4344-2019 ⓘ 57095192800; 16234881600; 53881692600 ⓘ mdshlim@gmail.com; ⓘ EYE ⓘ EYE ⓘ 0950-222X 1476-5454 35 3 SCIE OPHTHALMOLOGY ⓘ 2021 4.456 16.9 2.21 2025-07-30 ⓘ 15 18 ⓘ DRY EYE SYNDROME; OF-CARE TEST; INTRAOCULAR-PRESSURE; PREVALENCE; MULTICENTER; MEDICATION ⓘ ⓘ Aged; Case-Control Studies; Dry Eye Syndromes; Glaucoma; Glaucoma, Open-Angle; Humans; Matrix Metalloproteinase 9; Prospective Studies; Tears; alpha adrenergic receptor stimulating agent; antiglaucoma agent; beta adrenergic receptor blocking agent; carbonate dehydratase inhibitor; gelatinase B; polidronium chloride; travoprost; gelatinase B; adult; aged; Article; case control study; comparative study; controlled study; diabetes mellitus; female; five item dry eye questionnaire; human; hypertension; intraocular pressure; major clinical study; male; ocular surface disease; open angle glaucoma; oxford corneal stain scale; point of care testing; prospective study; protein expression; risk factor; Schirmer test; tear break-up time; tear film; topical treatment; visual system parameters; dry eye; glaucoma; lacrimal fluid; open angle glaucoma ⓘ English 2021 2021-03 10.1038/s41433-020-0993-y ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ How to keep patients and staff safe from accidental SARS-CoV-2 exposure in the emergency room: Lessons from South Korea's explosive COVID-19 outbreak ⓘ Objectives: We report our experience with an emergency room (ER) shutdown related to an accidental exposure to a patient with coronavirus disease 2019 (COVID-19) who had not been isolated. Setting: A 635-bed, tertiary-care hospital in Daegu, South Korea. Methods: To prevent nosocomial transmission of the disease, we subsequently isolated patients with suspected symptoms, relevant radiographic findings, or epidemiology. Severe acute respiratory coronavirus 2 (SARS-CoV-2) reverse-transcriptase polymerase chain reaction assays (RT-PCR) were performed for most patients requiring hospitalization. A universal mask policy and comprehensive use of personal protective equipment (PPE) were implemented. We analyzed effects of these interventions. Results: From the pre-shutdown period (February 10-25, 2020) to the post-shutdown period (February 28 to March 16, 2020), the mean hourly turnaround time decreased from 23:31 +/- 6:43 hours to 9:27 +/- 3:41 hours (P < .001). As a result, the proportion of the patients tested increased from 5.8% (N=1,037) to 64.6% (N=690) (P < .001) and the average number of tests per day increased from 3.8 +/- 4.3 to 24.7 +/- 5.0 (P < .001). All 23 patients with COVID-19 in the post-shutdown period were isolated in the ER without any problematic accidental exposure or nosocomial transmission. After the shutdown, several metrics increased. The median duration of stay in the ER among hospitalized patients increased from 4:30 hours (interquartile range [IQR], 2:17-9:48) to 14:33 hours (IQR, 6:55-24:50) (P < .001). Rates of intensive care unit admissions increased from 1.4% to 2.9% (P = .023), and mortality increased from 0.9% to 3.0% (P = .001). Conclusions: Problematic accidental exposure and nosocomial transmission of COVID-19 can be successfully prevented through active isolation and surveillance policies and comprehensive PPE use despite longer ER stays and the presence of more severely ill patients during a severe COVID-19 outbreak. ⓘ Kim, Yun Jeong; Choe, Jae Young; Kwon, Ki Tae; Hwang, Soyoon; Choi, Gyu-Seog; Sohn, Jin Ho; Kim, Jong Kun; Yeo, In Hwan; Cho, Yeon Joo; Ham, Ji Yeon; Song, Kyung Eun; Lee, Nan Young ⓘ Kyungpook Natl Univ, Sch Med, Dept Emergency Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Infect Dis, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Infect Control, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Chilgok Hosp, Colorectal Canc Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu, South Korea ⓘ ; lee, nan/HZM-0321-2023; Yeo, Inhwan/GXZ-7024-2022; Kim, Hanjin/KYP-2633-2024; Hwang, Soyoon/HHM-5762-2022; Kim, Joo/JAZ-0897-2023 ⓘ 57202340666; 57023107400; 9733850500; 57203160675; 8058759100; 55165818100; 55915816900; 57216816807; 57219251787; 56464754800; 57843936100; 57209204358 ⓘ ktkwon@knu.ac.kr; ⓘ INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY ⓘ INFECT CONT HOSP EP ⓘ 0899-823X 1559-6834 42 1 SCIE INFECTIOUS DISEASES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2021 6.52 16.9 0.84 2025-07-30 ⓘ 13 12 ⓘ MERS-COV OUTBREAK; PROTECTIVE EQUIPMENT ⓘ ⓘ COVID-19; COVID-19 Nucleic Acid Testing; Cross Infection; Emergency Service, Hospital; Female; Hospitalization; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Organizational Innovation; Patient Isolation; Personal Protective Equipment; Republic of Korea; Risk Management; SARS-CoV-2; Tertiary Care Centers; virus RNA; adult; Article; coronavirus disease 2019; cross-sectional study; data analysis software; do not resuscitate order; emergency ward; epidemic; female; heart arrest; hospital discharge; hospital mortality; hospital patient; hospitalization; human; intensive care unit; major clinical study; male; medical record review; medical staff; middle aged; nonhuman; nosocomial transmission; observational study; patient isolation; patient safety; personal experience; quarantine; real time polymerase chain reaction; retrospective study; reverse transcription polymerase chain reaction; RNA extraction; screening test; Severe acute respiratory syndrome coronavirus 2; South Korea; tertiary care center; turnaround time; university hospital; virus transmission; cross infection; hospital emergency service; isolation and purification; length of stay; organization; organization and management; patient isolation; procedures; protective equipment; risk management; therapy; virology ⓘ English 2021 2021-01 10.1017/ice.2020.376 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Nanocages displaying SIRP gamma clusters combined with prophagocytic stimulus of phagocytes potentiate anti-tumor immunity ⓘ Antigen-presenting cells (APCs), including macrophages and dendritic cells (DCs), play a crucial role in bridging innate and adaptive immunity; thereby, innate immune checkpoint blockade-based therapy is an attractive approach for the induction of sustainable tumor-specific immunity. The interaction between the cluster of differentiation 47 (CD47) on tumor and signal-regulatory protein alpha (SIRP alpha) on phagocytic cells inhibits the phagocytic function of APCs, acting as a "don't eat me" signal. Accordingly, CD47 blockade is known to increase tumor cell phagocytosis, eliciting tumor-specific CD8(+) T-cell immunity. Here, we introduced a nature-derived nanocage to deliver SIRP gamma for blocking of antiphagocytic signaling through binding to CD47 and combined it with prophagocytic stimuli using a metabolic reprogramming reagent for APCs (CpG-oligodeoxynucleotides). Upon delivering the clustered SIRP gamma variant, the nanocage showed enhanced CD47 binding profiles on tumor cells, thereby promoting active engulfment by phagocytes. Moreover, combination with CpG potentiated the prophagocytic ability, leading to the establishment of antitumorigenic surroundings. This combination treatment could competently inhibit tumor growth by invigorating APCs and CD8(+) T-cells in TMEs in B16F10 orthotopic tumor models, known to be resistant to CD47-targeting therapeutics. Collectively, enhanced delivery of an innate immune checkpoint antagonist with metabolic modulation stimuli of immune cells could be a promising strategy for arousing immune responses against cancer. ⓘ Choi, Yoonjeong; Nam, Gi-Hoon; Kim, Gi Beom; Kim, Seohyun; Kim, Yoon Kyoung; Kim, Seong A.; Kim, Ha-Jeong; Lee, Eun Jung; Kim, In-San ⓘ Korea Univ, KU KIST Grad Sch Converging Sci & Technol, Seoul, South Korea; Korea Inst Sci & Technol, Biomed Res Inst, Ctr Theragnosis, Seoul, South Korea; Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA; Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu, South Korea; Kyungpook Natl Univ, Sch Appl Chem Engn, Dept Chem Engn, Daegu, South Korea ⓘ ; Lee, Seung Eun/ABG-1607-2021; Seong, Ki/Y-6083-2019; Nam, Gi-Hoon/I-6664-2018 ⓘ 57199930108; 57192919427; 57197865834; 57212447863; 57202143775; 57211273596; 57191717512; 57239965200; 34770432800 ⓘ eunjunglee@knu.ac.kr;iskim14@kist.re.kr; ⓘ CANCER GENE THERAPY ⓘ CANCER GENE THER ⓘ 0929-1903 1476-5500 28 9 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;GENETICS & HEREDITY;MEDICINE, RESEARCH & EXPERIMENTAL;ONCOLOGY ⓘ 2021 5.854 16.9 0.57 2025-07-30 ⓘ 10 10 ⓘ SIGNAL-REGULATORY PROTEIN; ANTIGEN PRESENTATION; CD47 BLOCKADE; CPG-DNA; CELLS; ALPHA; RECEPTORS; TARGET; MACROPHAGES; ACTIVATION ⓘ ⓘ Animals; Antigens, Differentiation; Cell Line, Tumor; Disease Models, Animal; Ferritins; Humans; Immunotherapy; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nanostructures; Neoplastic Cells, Circulating; Oxidoreductases; Phagocytosis; Receptors, Immunologic; CD3 antigen; CD47 antigen; CD8 antigen; CpG oligodeoxynucleotide; ferritin; fsyv; Hermes antigen; immune checkpoint inhibitor; lysosome associated membrane protein 1; nanocage; plasmid vector; receptor type tyrosine protein phosphatase C; recombinant protein; unclassified drug; differentiation antigen; ferritin; FTH1 protein, human; immunoglobulin receptor; nanomaterial; oxidoreductase; SIRPG protein, human; adaptive immunity; animal cell; animal experiment; animal model; antigen presenting cell; antitumorigenic activity; Article; B16-BL6 cell line; bone marrow derived macrophage; cancer gene therapy; cancer inhibition; carboxy terminal sequence; CD8+ T lymphocyte; comparative study; controlled study; dendritic cell; drug efficacy; drug synthesis; erythrocyte; expression vector; femur; flow cytometry; fluorescence microscopy; gene cluster; gene mutation; genetic variability; hemolysis assay; immune response; in vivo study; innate immunity; male; molecular cloning; mouse; neoplasm; nonhuman; nonviral gene delivery system; nuclear reprogramming; phagocyte; phagocytosis; photon correlation spectroscopy; point mutation; polyacrylamide gel electrophoresis; protein binding; protein expression; protein multimerization; protein purification; size exclusion chromatography; tibia; transmission electron microscopy; tumor growth; tumor immunity; tumor microenvironment; tumor model; tumor volume; Western blotting; animal; C57BL mouse; chemistry; disease model; experimental melanoma; genetics; human; immunology; immunotherapy; phagocytosis; procedures; tumor cell line; tumor embolism ⓘ English 2021 2021-09 10.1038/s41417-021-00372-y ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Pullout strength of pedicle screws using cadaveric vertebrae with or without artificial demineralization ⓘ OBJECTIVES: To evaluate the differences in the pullout strength and displacement of pedicle screws in cadaveric thoracolumbar vertebrae with or without artificial demineralization. METHODS: Five human lumbar and five thoracic vertebrae from one cadaver were divided into two hemivertebrae. The left-side specimens were included in the simulated osteopenic model group and the right-side bones in a control group. In the model group, we immersed each specimen in HCl (1 N) solution for 40 minutes. We measured bone mineral density (BMD) using dual-energy X-ray absorptiometry and quantitative computerized tomography. We inserted polyaxial pedicle screws into the 20 pedicles of the cadaveric lumbar and thoracic spine after measuring the BMD of the 2 hemivertebrae of each specimen. We measured the pullout strength and displacement of the screws before failure in each specimen using an Instron system. RESULTS: The average pullout strength of the simulated osteopenic model group was 76% that of the control group. In the control and model groups, the pullout strength was 1678.87 +/- 358.96 N and 1283.83 +/- 341.97 N, respectively, and the displacement was 2.07 +/- 0.34 mm and 2.65 +/- 0.50 mm, respectively (p<.05). We detected positive correlations between pullout strength and BMD in the control group and observed a negative correlation between displacement and BMD in the model group. CONCLUSIONS: By providing an anatomically symmetric counterpart, the human cadaveric model with or without demineralization can be used as a test bed for pullout tests of the spine. In the simulated osteopenic model group, pullout strength was significantly decreased compared with the untreated control group. CLINICAL SIGNIFICANCE: Decreased bone mineral density may significantly reduce the pullout strength of a pedicle screw, even though the range is osteopenic rather than osoteoporotic. (C) 2021 Published by Elsevier Inc. ⓘ Lee, Suk-Joong; Lee, Jin-Han; Lee, Hyun-Joo; Oh, Ji Won; Park, Il-Hyung ⓘ Gyeongsang Natl Univ, Dept Orthopaed Surg, Sch Med, Chang Won, South Korea; Gyeongsang Natl Univ, Changwon Hosp, Chang Won, South Korea; Kyungpook Natl Univ, Sch Med, Dept Orthopaed Surg, 130 Dongduk Ro, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, 130 Dongduk Ro, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Anat, 130 Dongduk Ro, Daegu, South Korea; Kyungpook Natl Univ Hosp, Biomed Res Inst, 130 Dongduk Ro, Daegu, South Korea ⓘ Oh, Ji/AAZ-3153-2020 ⓘ 57078230800; 57202149598; 58838750100; 36093206200; 35076285100 ⓘ ihpark@knu.ac.kr; ⓘ SPINE JOURNAL ⓘ SPINE J ⓘ 1529-9430 1878-1632 21 9 SCIE CLINICAL NEUROLOGY;ORTHOPEDICS ⓘ 2021 4.297 16.9 0.65 2025-07-30 ⓘ 5 6 Artificial demineralization; Bone mineral density; Cadaver; Pedicle screw; Pullout strength; Simulated osteopenic model; Spine ⓘ OSTEOPOROTIC SPINE; BONE QUALITY; FIXATION; AUGMENTATION; INSTRUMENTATION; COMPLICATIONS; STABILITY; DENSITY; DESIGNS ⓘ Artificial demineralization; Bone mineral density; Cadaver; Pedicle screw; Pullout strength; Simulated osteopenic model; Spine ⓘ Biomechanical Phenomena; Bone Density; Cadaver; Humans; Lumbar Vertebrae; Pedicle Screws; Thoracic Vertebrae; Article; artificial demineralization; biomechanics; bone demineralization; bone density; cadaver; comparative study; computer assisted tomography; controlled study; disease simulation; dual energy X ray absorptiometry; human; human tissue; lumbar spine; lumbar vertebra; mechanical test; osteopenia; simulation; thoracic spine; thoracic vertebra; thoracolumbar spine; vertebra body; biomechanics; cadaver; pedicle screw; surgery ⓘ English 2021 2021-09 10.1016/j.spinee.2021.04.010 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Editorial Material ⓘ Rapid diagnostic testing for antimicrobial stewardship: Utility in Asia Pacific ⓘ Rapid diagnostic testing (RDT) can provide prompt, accurate identification of infectious organisms and be a key component of antimicrobial stewardship (AMS) programs. However, their use is less widespread in Asia Pacific than western countries. Cost can be prohibitive, particularly in less resource-replete settings. A selective approach is required, possibly focusing on the initiation of antimicrobials, for differentiating bacterial versus viral infections and identifying locally relevant tropical diseases. Across Asia Pacific, more data are needed on RDT use within AMS, focusing on the impact on antimicrobial usage, patient morbidity and mortality, and cost effectiveness. Moreover, in the absence of formal guidelines, regional consensus statements to guide clinical practice are warranted. These will provide a regionally relevant definition for RDT; greater consensus on its role in managing infections; advice on implementation and overcoming barriers; and guidance on optimizing human resource capacity. By addressing these issues, the outcomes of AMS programs should improve. ⓘ Apisarnthanarak, Anucha; Kim, Hong Bin; Moore, Luke; Xiao, Yonghong; Singh, Sanjeev; Doi, Yohei; Kwa, Andrea Lay-Hoon; Sri La Sri Ponnampalavanar, Sasheela; Cao, Qing; Kim, Shin-Woo; Lee, Hyukmin; Santanirand, Pitak ⓘ Thammasat Univ Hosp, Infect Dis Div, Pathum Thani, Thailand; Seoul Natl Univ, Coll Med, Bundang Hosp, Internal Med, Seongnam, South Korea; Chelsea & Westminster NHS Fdn Trust, Infect Dis & Clin Microbiol, London, England; North West London Pathol Imperial Coll Healthcare, Med Microbiol, London, England; Imperial Coll, London, England; Zhejiang Univ, Sch Med, Affiliated Hosp 1, State Key Lab Diag & Treatment Infect Dis, Hangzhou, Peoples R China; Amrita Univ, Amrita Inst Med Sci, Hosp Adm & Med Serv, Kochi, Kerala, India; Univ Pittsburgh, Sch Med, Pittsburgh, PA USA; Fujita Hlth Univ, Sch Med, Dept Microbiol, Toyoake, Aichi, Japan; Fujita Hlth Univ, Sch Med, Dept Infect Dis, Toyoake, Aichi, Japan; Singapore Gen Hosp, Pharm Dept, Singapore, Singapore; Duke Natl Univ Singapore Med Sch, Emerging Infect Dis Program, Singapore, Singapore; Univ Malaya, Fac Med, Dept Med, Kuala Lumpur, Malaysia; Shanghai Jiao Tong Univ, Affiliated Shanghai Childrens Med Ctr, Shanghai, Peoples R China; Kyungpook Natl Univ Hosp, Internal Med, Daegu, South Korea; Yonsei Univ, Coll Med, Dept Lab Med, Seoul, South Korea; Korean Soc Lab Med, Seoul, South Korea; Mahidol Univ, Ramathibodi Hosp, Fac Med, Clin Pathol, Bangkok, Thailand ⓘ Xiao, Yonghong/AFS-9054-2022; Santanirand, Pitak/IXN-1758-2023; LA SRI PONNAMPALAVANAR, SASHEELA/B-9703-2010; Moore, Luke/Q-1012-2018; Doi, Yohei/C-7110-2013; Kim, Hee/AAU-6368-2021; Kim, Hong Bin/J-5452-2012 ⓘ 55552662200; 35307429400; 54906028100; 7403260799; 59897457100; 8521487500; 8549468400; 36768852500; 57203559749; 57189703358; 8872234300; 16317162900 ⓘ anapisarn@yahoo.com; ⓘ INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY ⓘ INFECT CONT HOSP EP ⓘ 0899-823X 1559-6834 42 7 SCIE INFECTIOUS DISEASES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2021 6.52 16.9 0.32 2025-07-30 ⓘ 9 9 ⓘ ANTIBIOTIC STEWARDSHIP; BLOOD-STREAM ⓘ ⓘ Anti-Bacterial Agents; Anti-Infective Agents; Antimicrobial Stewardship; Asia; Diagnostic Techniques and Procedures; Humans; antibiotic agent; antiinfective agent; antimicrobial stewardship; Asia; consensus; coronavirus disease 2019; diagnostic procedure; health care planning; human; infection; pandemic; Review; diagnostic procedure ⓘ English 2021 2021-07 10.1017/ice.2021.149 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Mesostructured g-C3N4 nanosheets interconnected with V2O5 nanobelts as electrode for coin-cell-type-asymmetric supercapacitor device ⓘ In this study, low-cost, noble-metal-free, ecologically friendly, high-performance coin-cell-type supercapacitors are constructed using an efficient one-pot approach. Two novel nanostructures comprising V2O5 nanobelts-one with and one without cetyltrimethylammonium bromide (CTAB)-modified g-C3N4-are synthesized via a hy-drothermal process (g-C3N4 nanosheet (CN)/VO and CTAB-modified pore-rich g-C3N4 nanosheet [CCN]/VO nanostructures, respectively). CTAB is used as a sacrificial template to generate mesoporous structures in the g-C3N4 nanosheets. The CCN/VO nanostructure exhibits a larger surface area (73.5 m(2)/g) than that of CN/VO (54.1 m(2)/g) and superior specific capacity (192.3 mAh/g/0.5 A/g). In addition, an asymmetric capacitive device composed of the CCN/VO nanostructure and activated carbon is fabricated. It exhibits a remarkable energy density of 96.6 Wh/kg at 811.0 W/kg in the voltage frame of 1.5 V, along with a remarkable cycling stability of 90.2% over 5000 cycles. Moreover, the CCN/VO nanostructure electrode is used to reproduce experimental cyclic voltammetry curves in a numerical simulation model. The unique CCN/VO with a 2D/1D nanostructure exhibits superior electrochemical capacitor characteristics. This result could inspire novel nanostructured electrode ma-terials that can potentially be used in high-performance supercapacitor applications. (C) 2021 Elsevier Ltd. All rights reserved. ⓘ Devarayapalli, K. C.; Lee, K.; Do, H-B; Dang, N. N.; Yoo, K.; Shim, J.; Vattikuti, S. V. Prabhakar ⓘ Kyungpook Natl Univ, Sch Nano & Mat Sci & Engn, 2559 Gyeongsang Daero, Sangju, Gyeongbuk, South Korea; Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, 2559 Gyeongsang Daero, Sangju 37224, South Korea; Ho Chi Minh City Univ Technol & Educ, 01 Vo Van Ngan, Ho Chi Minh City 700000, Vietnam; Duy Tan Univ, Inst Fundamental & Appl Sci, Future Mat & Devices Lab, Ho Chi Minh City 700000, Vietnam; Duy Tan Univ, Fac Environm & Chem Engn, Da Nang 550000, Vietnam; Yeungnam Univ, Sch Mech Engn, Gyongsan 38541, South Korea ⓘ ; Lee, Kiyoung/J-8680-2013; Do, Huy-Binh/T-3236-2017; VATTIKUTI, S/I-5237-2019 ⓘ 15069351300; 57219211501; 56300939500; 57216456831; 55949465000; 16040548500; 57542619100 ⓘ kiyoung@knu.ac.kr;nguyendangnam@duytan.edu.vn;jshim@ynu.ac.kr;drprabu@ynu.ac.kr; ⓘ MATERIALS TODAY ENERGY ⓘ MATER TODAY ENERGY ⓘ 2468-6069 21 SCIE CHEMISTRY, PHYSICAL;ENERGY & FUELS;MATERIALS SCIENCE, MULTIDISCIPLINARY ⓘ 2021 9.257 17.0 5.39 2025-07-30 ⓘ 84 83 Layered material; Energy storage; Heterojunction; Nanostructure; Hydrothermal reaction ⓘ BINDER-FREE ELECTRODE; REDUCED GRAPHENE OXIDE; CARBON NITRIDE; ELECTROCHEMICAL PROPERTIES; FACILE SYNTHESIS; HIGH-ENERGY; PERFORMANCE; FABRICATION; PHOTOCATALYST; HETEROSTRUCTURES ⓘ Energy storage; Heterojunction; Hydrothermal reaction; Layered material; Nanostructure ⓘ Cyclic voltammetry; Electrodes; Nanosheets; Precious metals; Supercapacitor; Vanadium pentoxide; Asymmetric supercapacitor; Cetyltrimethylammonium bromide; Cyclic voltammetry curves; Electrochemical capacitor; Mesoporous structures; Nanostructured electrode materials; Sacrificial templates; Supercapacitor application; Nanobelts ⓘ English 2021 2021-09 10.1016/j.mtener.2021.100699 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Real hypersurfaces with isometric Reeb flow in Kahler manifolds ⓘ We investigate the structure of real hypersurfaces with isometric Reeb flow in Kahler manifolds. As an application we classify real hypersurfaces with isometric Reeb flow in irreducible Hermitian symmetric spaces of compact type. ⓘ Berndt, Jurgen; Suh, Young Jin ⓘ Kings Coll London, Dept Math, London WC2R 2LS, England; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Kyungpook Natl Univ, RIRCM, Daegu 41566, South Korea ⓘ ⓘ 7006433385; 7202260479 ⓘ jurgen.berndt@kcl.ac.uk;yjsuh@knu.ac.kr; ⓘ COMMUNICATIONS IN CONTEMPORARY MATHEMATICS ⓘ COMMUN CONTEMP MATH ⓘ 0219-1997 1793-6683 23 1 SCIE MATHEMATICS, APPLIED;MATHEMATICS ⓘ 2021 1.708 17.0 1.87 2025-07-30 ⓘ 12 13 Real hypersurfaces; Reeb flow; Kahler manifolds; Hermitian symmetric spaces ⓘ INDEX ⓘ Hermitian symmetric spaces; Kähler manifolds; Real hypersurfaces; Reeb flow ⓘ ⓘ English 2021 2021-02 10.1142/s0219199719500391 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Editorial Material ⓘ Lateral Pelvic Node Metastasis in Locally Advanced Rectal Cancer: Are We Exaggerating or Ignoring? ⓘ ⓘ Choi, Gyu-Seog ⓘ Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Colorectal Canc Ctr, Daegu, South Korea ⓘ ⓘ 8058759100 ⓘ kyuschoi@mail.knu.ac.kr; ⓘ ANNALS OF SURGICAL ONCOLOGY ⓘ ANN SURG ONCOL ⓘ 1068-9265 1534-4681 28 11 SCIE ONCOLOGY;SURGERY ⓘ 2021 4.339 17.1 0 2025-07-30 ⓘ 0 0 ⓘ DISSECTION ⓘ ⓘ Humans; Lymph Node Excision; Lymph Nodes; Pelvis; Rectal Neoplasms; advanced cancer; cancer prognosis; clinical outcome; Editorial; human; lateral pelvic node; lymph node; lymph node metastasis; morbidity; neoadjuvant therapy; nuclear magnetic resonance imaging; overall survival; patient selection; randomized controlled trial (topic); rectum cancer; recurrence free survival; total mesorectal excision; lymph node dissection; pelvis; rectum tumor ⓘ English 2021 2021-10 10.1245/s10434-021-10558-1 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Survival of Breast-Conserving Surgery Plus Radiotherapy versus Total Mastectomy in Early Breast Cancer ⓘ Background Breast-conserving surgery (BCS) has been reported to have better survival rates when compared with total mastectomy (TM) in early breast cancer. We evaluated the long-term outcomes of Korean women with early breast cancer who underwent either BCS plus radiotherapy (RT) or TM. Methods In this population-based study, we evaluated 45,770 patients from the Korean Breast Cancer Registry (KBCR) who were diagnosed with early breast cancer, and divided them into the BCS + RT and TM groups. To minimize bias caused by factors other than the surgical method, we used exact match pairing of prognostic factors. We compared the 10-year overall survival (OS) and breast cancer-specific survival (BCSS) before and after exact matching. As the KBCR is a multicenter, online-based registry program, we used the Asan Medical Center (AMC) database, a single-center database, to validate the results from the KBCR database. Results In both the KBCR and AMC cohorts, the BCS + RT group showed better OS and BCSS than the TM group, before and after exact matching. For the KBCR cohort after exact matching, the hazard ratios for OS and BCSS were 1.541 (95% confidence interval [CI] 1.392-1.707, p < 0.001) and 1.405 (95% CI 1.183-1.668, p < 0.001), respectively, favoring the BCS + RT group. For the AMC cohort after exact matching, the hazard ratios for OS and BCSS were 1.854 (95% CI 1.476-2.328, p < 0.001) and 1.807 (95% CI 1.186-2.752, p = 0.006), respectively. Conclusions Our results suggest that BCS + RT is at least equivalent to TM in terms of OS and may affect treatment decisions in early breast cancer patients. ⓘ Kim, Hakyoung; Lee, Sae Byul; Nam, Seok-Jin; Lee, Eun Sook; Park, Byeong-Woo; Park, Ho Yong; Lee, Hyouk Jin; Kim, Jisun; Chung, Yong; Kim, Hee Jeong; Ko, Beom Seok; Lee, Jong Won; Son, Byung Ho; Ahn, Sei Hyun ⓘ Univ Ulsan, Coll Med, Asan Med Ctr, Div Breast Surg,Dept Surg, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Surg, Seoul, South Korea; Natl Canc Ctr, Res Inst & Hosp, Ctr Breast Canc, Goyang, Gyeonggi, South Korea; Yonsei Univ, Coll Med, Severance Hosp, Dept Surg, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Segyero Hosp, Busan, South Korea ⓘ Kim, HakYoung/KII-9240-2024; PARK, JUN-YOUNG/P-5981-2015; Lee, Jong-Seok/J-5603-2012; Lee, Jong-Mok/KVY-9550-2024 ⓘ 56606776100; 56556623100; 7402276023; 57217265200; 7402834528; 56564377200; 56709043900; 55913243600; 57203219109; 14626479600; 56781006300; 55992285000; 26028949200; 55648899200 ⓘ newstar153@hanmail.net; ⓘ ANNALS OF SURGICAL ONCOLOGY ⓘ ANN SURG ONCOL ⓘ 1068-9265 1534-4681 28 9 SCIE ONCOLOGY;SURGERY ⓘ 2021 4.339 17.1 3.05 2025-07-30 ⓘ 35 34 ⓘ ⓘ ⓘ Breast Neoplasms; Female; Humans; Mastectomy; Mastectomy, Segmental; Mastectomy, Simple; Neoplasm Staging; Radiotherapy, Adjuvant; epidermal growth factor receptor 2; adult; age; Article; breast cancer; cancer grading; cancer prognosis; cancer radiotherapy; cancer registry; cancer specific survival; cancer staging; cancer surgery; cancer survival; clinical effectiveness; clinical evaluation; cohort analysis; comparative study; confidence interval; controlled study; early cancer; female; follow up; hazard ratio; histopathology; human; human tissue; Korean (people); long term survival; major clinical study; middle aged; multicenter study; outcome assessment; overall survival; partial mastectomy; population research; prospective study; simple mastectomy; adjuvant radiotherapy; breast tumor; clinical trial; mastectomy; pathology; simple mastectomy ⓘ English 2021 2021-09 10.1245/s10434-021-09591-x ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Review ⓘ A Review of Plasma Synthesis Methods for Polymer Films and Nanoparticles under Atmospheric Pressure Conditions ⓘ In this paper, we present an overview of recent approaches in the gas/aerosol-through-plasma (GATP) and liquid plasma methods for synthesizing polymer films and nanoparticles (NPs) using an atmospheric-pressure plasma (APP) technique. We hope to aid students and researchers starting out in the polymerization field by compiling the most commonly utilized simple plasma synthesis methods, so that they can readily select a method that best suits their needs. Although APP methods are widely employed for polymer synthesis, and there are many related papers for specific applications, reviews that provide comprehensive coverage of the variations of APP methods for polymer synthesis are rarely reported. We introduce and compile over 50 recent papers on various APP polymerization methods that allow us to discuss the existing challenges and future direction of GATP and solution plasma methods under ambient air conditions for large-area and mass nanoparticle production. ⓘ Jang, Hyo Jun; Jung, Eun Young; Parsons, Travis; Tae, Heung-Sik; Park, Choon-Sang ⓘ Kyungpook Natl Univ, Coll IT Engn, Sch Elect & Elect Engn, Daegu 41566, South Korea; Procter & Gamble Co, GBS Global Business Serv IT, Cincinnati, OH 45202 USA; Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 41566, South Korea; Kansas State Univ, Coll Engn, Dept Elect & Comp Engn, Manhattan, KS 66506 USA ⓘ ⓘ 57207956623; 57203199724; 57194191408; 7006298844; 16025295400 ⓘ bs00201@knu.ac.kr;eyjung@knu.ac.kr;trav.parson@gmail.com;hstae@ee.knu.ac.kr;purplepcs@ksu.edu; ⓘ POLYMERS ⓘ POLYMERS-BASEL ⓘ 2073-4360 13 14 SCIE POLYMER SCIENCE ⓘ 2021 4.967 17.2 1 2025-07-30 ⓘ 61 66 atmospheric-pressure plasma; solution plasma; plasma polymerization; polymer films; room temperature growth; nanoparticles ⓘ POLYETHYLENE LDPE FILMS; SURFACE MODIFICATION; CO-POLYMERIZATION; LIQUID PLASMA; DEPOSITION; COATINGS; ANILINE; IMPROVEMENT; ENHANCEMENT; WETTABILITY ⓘ Atmospheric-pressure plasma; Nanoparticles; Plasma polymerization; Polymer films; Room temperature growth; Solution plasma ⓘ Atmospheric pressure; Nanoparticles; Plasma polymerization; Semiconducting films; Synthesis (chemical); Ambient air conditions; Atmospheric pressure plasmas; Nano-particle production; Nanoparticle (NPs); Plasma synthesis; Polymer synthesis; Polymerization method; Solution plasmas; Polymer films ⓘ English 2021 2021-07 10.3390/polym13142267 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ A Study on the Red Clay Binder Stabilized with a Polymer Aqueous Solution ⓘ In this study, the performance evaluation was performed by adding a polymer aqueous (PA) solution as a new additive of the red clay binder for use in the rammed-earth construction method. The evaluation items were compressive strength, water erosion, shrinkage, crystal structure, and microstructure. As a result of the experiment, the binder was improved by efficiently bonding the silica particles by the polymerized polymer. It was confirmed that adding a PA solution to red clay enhances the compressive strength, which is further improved when 5 wt% poly(Acrylic acid(AA)-co-Acrylamide(AM)) is added to the PA solution. Microstructural analysis indicated that the addition of a PA solution facilitates effective bonding of the silica particles of red clay to form hydrogen bonding with poly(AA-co-AM) and encourages aggregate formation. Therefore, the study confirmed that PA solution can be applied to satisfy the performance requirements of the rammed-earth construction by improving the durability and strength of the binder. ⓘ Kim, Jinsung; Choi, Hyeonggil; Rye, Hyeun-Min; Yoon, Keun-Byoung; Lee, Dong-Eun ⓘ Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu 41566, South Korea ⓘ ⓘ 57219198374; 56430165800; 57221329831; 7401607550; 56605563300 ⓘ kjs07406@knu.ac.kr;hgchoi@knu.ac.kr;bc1532@knu.ac.kr;kbyoon@knu.ac.kr;dolee@knu.ac.kr; ⓘ POLYMERS ⓘ POLYMERS-BASEL ⓘ 2073-4360 13 1 SCIE POLYMER SCIENCE ⓘ 2021 4.967 17.2 0.45 2025-07-30 ⓘ 8 8 rammed-earth construction; polymer aqueous solution; poly(AA-co-AM); hydrogen bonding; microstructure ⓘ RAMMED EARTH; MECHANICAL CHARACTERISTICS; LIME; PERFORMANCE; DURABILITY; BEHAVIOR ⓘ Hydrogen bonding; Microstructure; Poly(AA-co-AM); Polymer aqueous solution; Rammed-earth construction ⓘ Amides; Ascorbic acid; Crystal structure; Hydrogen bonds; Polymers; Silica; Acrylic acids; Aggregate formation; Evaluation items; Microstructural analysis; Performance requirements; Polymer aqueous solution; Silica particles; Water erosion; Compressive strength ⓘ English 2021 2021-01 10.3390/polym13010054 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Application of an Acrylic Polymer and Epoxy Emulsion to Red Clay and Sand ⓘ The use of nontraditional soil stabilizers increases. Various new soil binding agents are under study to augment renewability and sustainability of an earth structure. However, despite increasing interest involved in red clay, there is minimal research investigating the stabilizing red clay with polymer. This paper presents the findings obtained by applying the acrylic polymer and epoxy emulsion as binding agent for red clay and that for sand. The epoxy-hardener ratio, amount of epoxy emulsion, and amount of polymer aqueous solution were manipulated to quantify their effects on red clay and sand, respectively. After compacting a pair of cylindrical samples of which diameter and height are 5 cm and 10 cm, respectively, it is cured for 3 and 7 days in a controlled condition. Each pair is produced to represent the engineering performance at each data point in the solution space. An optimal composition of the binding agents for red clay and that for sand mixture are identified by experimenting every data point. In addition, given lime into each sample, the maximum unconfined compressive strength (UCS) endured by red clay sample and that by sand sample are 2243 and 1493 kPa, respectively. The UCS obtained by the sample mixed with clay and sand reaches 2671 kPa after seven days of curing. It confirms that the addition of lime remarkably improves the UCS. When the clay-sand mixture, of which the ratio is 70:30, includes 5% lime, the UCS of the mixture outperforms. Indeed, these findings, i.e., the optimal proportion of components, may contribute to the increase of initial and long-term strength of an earth structure, hence improving the renewability and sustainability of the earth construction method. ⓘ Park, Sung-Sik; Lee, Jung-Shin; Yoon, Keun-Byoung; Woo, Seung-Wook; Lee, Dong-Eun ⓘ Kyungpook Natl Univ, Dept Civil Engn, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Intelligent Construct Automat Ctr, Global Plaza 905,80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, 80 Daehakro, Daegu 41566, South Korea ⓘ Lee, Jung Bok/HHZ-3200-2022 ⓘ 36241850300; 57210867035; 7401607550; 57212917862; 56605563300 ⓘ sungpark@knu.ac.kr;jhjs14@knu.ac.kr;kbyoon@knu.ac.kr;geowsw@knu.ac.kr;dolee@knu.ac.kr; ⓘ POLYMERS ⓘ POLYMERS-BASEL ⓘ 2073-4360 13 19 SCIE POLYMER SCIENCE ⓘ 2021 4.967 17.2 0.32 2025-07-30 ⓘ 7 6 red clay; sand; acrylic polymer; epoxy; unconfined compressive strength ⓘ STRENGTH PROPERTIES; RESIN; BEHAVIOR; STABILIZATION ⓘ Acrylic polymer; Epoxy; Red clay; Sand; Unconfined compressive strength ⓘ Compressive strength; Curing; Lime; Sand; Soils; Sustainable development; Acrylic polymers; Binding agent; Datapoints; Earth structures; Epoxy; Polymer aqueous solution; Red clay; Red sand; Soil stabilizers; Unconfined compressive strength; Emulsification ⓘ English 2021 2021-10 10.3390/polym13193410 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Comparative Study on Toughening Effect of PTS and PTK in Various Epoxy Resins ⓘ This study investigated the toughening effect of in situ polytriazoleketone (PTK) and polytriazolesulfone (PTS) toughening agent when applied to various epoxy resins, such as diglycidyl ether of bisphenol A (DGEBA), diglycidyl ether of bisphenol F (DGEBF), and triglycidyl p-aminophenol (TGAP) with 3,3 '-diaminodiphenylsulfone as a curing agent. The fracture toughness, tensile properties, and thermal properties of the prepared epoxy samples were evaluated and compared. When PTK was mixed with DGEBF, the fracture toughness was improved by 27% with 8.6% increased tensile strength compared to the untoughened DGEBF. When PTS was mixed with TGAP, the fracture toughness was improved by 51% without decreasing tensile properties compared to the untoughened TGAP. However, when PTK or PTS was mixed with other epoxy resins, the fracture toughness decreased or improved with decreasing tensile properties. This is attributed to the poor miscibility between the solid-state monomer of PTK (4,4 '-bis(propynyloxy)benzophenone (PBP)) or PTS (4,4 '-sulfonylbis(propynyloxy)benzene (SPB)) and the epoxy resin, resulting in the polymerization of low molecular weight PTK or PTS in epoxy resin. Therefore, the toughening effect of PTK or PTS can be maximized by the appropriate selection of epoxy resin based on the miscibility between PBP or SPB and the resin. ⓘ Kwon, Woong; Han, Minwoo; Kim, Jongwon; Jeong, Euigyung ⓘ Kyungpook Natl Univ, Dept Text Syst Engn, Daegu 41566, South Korea; Yeungnam Univ, Dept Fiber Syst Engn, Gyongsan 38541, South Korea ⓘ ⓘ 57208867074; 57222077344; 56263936700; 35885596300 ⓘ kwoong7242@naver.com;gksalsdn93@gmail.com;kjwfiber@ynu.ac.kr;wolfpack@knu.ac.kr; ⓘ POLYMERS ⓘ POLYMERS-BASEL ⓘ 2073-4360 13 4 SCIE POLYMER SCIENCE ⓘ 2021 4.967 17.2 0.19 2025-07-30 ⓘ 9 7 epoxy resin; toughening agent; fracture toughness; polytriazoleketone; polytriazolesulfone ⓘ ⓘ Epoxy resin; Fracture toughness; Polytriazoleketone; Polytriazolesulfone; Toughening agent ⓘ Epoxy resins; Ethers; Phenols; Solubility; Tensile strength; Comparative studies; Diaminodiphenylsulfone; Diglycidyl ether of bisphenol; Diglycidyl ether of bisphenol-A; Epoxy samples; Low molecular weight; Toughening agents; Toughening effects; Fracture toughness ⓘ English 2021 2021-02 10.3390/polym13040518 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Demineralized Dentin Matrix Particle-Based Bio-Ink for Patient-Specific Shaped 3D Dental Tissue Regeneration ⓘ Demineralized dentin matrix (DDM)-based materials have been actively developed and are well-known for their excellent performance in dental tissue regeneration. However, DDM-based bio-ink suitable for fabrication of engineered dental tissues that are patient-specific in terms of shape and size, has not yet been developed. In this study, we developed a DDM particle-based bio-ink (DDMp bio-ink) with enhanced three-dimensional (3D) printability. The bio-ink was prepared by mixing DDM particles and a fibrinogen-gelatin mixture homogeneously. The effects of DDMp concentration on the 3D printability of the bio-ink and dental cell compatibility were investigated. As the DDMp concentration increased, the viscosity and shear thinning behavior of the bio-ink improved gradually, which led to the improvement of the ink's 3D printability. The higher the DDMp content, the better were the printing resolution and stacking ability of the 3D printing. The printable minimum line width of 10% w/v DDMp bio-ink was approximately 252 mu m, whereas the fibrinogen-gelatin mixture was approximately 363 mu m. The ink's cytocompatibility test with dental pulp stem cells (DPSCs) exhibited greater than 95% cell viability. In addition, as the DDMp concentration increased, odontogenic differentiation of DPSCs was significantly enhanced. Finally, we demonstrated that cellular constructs with 3D patient-specific shapes and clinically relevant sizes could be fabricated through co-printing of polycaprolactone and DPSC-laden DDMp bio-ink. ⓘ Han, Jonghyeuk; Jeong, Wonwoo; Kim, Min-Kyeong; Nam, Sang-Hyeon; Park, Eui-Kyun; Kang, Hyun-Wook ⓘ Ulsan Natl Inst Sci & Technol, Dept Biomed Engn, 50 UNIST Gil, Ulsan 44919, South Korea; Kyungpook Natl Univ, Dept Pathol & Regenerat Med, Sch Dent, 2177 Dalgubeol Daero, Daegu 41940, South Korea ⓘ ; Kang, Hyun-Wook/AAY-1766-2021 ⓘ 57188696601; 57209730344; 57215135890; 57209806061; 37071072400; 57203618619 ⓘ g14619@unist.ac.kr;wwjeong@unist.ac.kr;minkkim@unist.ac.kr;aay0805@naver.com;epark@knu.ac.kr;hkang@unist.ac.kr; ⓘ POLYMERS ⓘ POLYMERS-BASEL ⓘ 2073-4360 13 8 SCIE POLYMER SCIENCE ⓘ 2021 4.967 17.2 1.67 2025-07-30 ⓘ 27 29 demineralized dentin matrix; bio-ink; 3D bioprinting; dental tissue engineering ⓘ ⓘ 3D bioprinting; Bio-ink; Demineralized dentin matrix; Dental tissue engineering ⓘ Mixtures; Shear thinning; Stem cells; Tissue; Tissue regeneration; Cytocompatibility tests; Demineralized dentin matrixes; Dental pulp stem cells; Dental tissue regeneration; Patient specific; Printing resolution; Shear-thinning behavior; Threedimensional (3-d); 3D printers ⓘ English 2021 2021-04 10.3390/polym13081294 ⓘ 바로가기 바로가기 바로가기 바로가기
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