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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Ready-to-Use Nanofiber Membrane-Integrated Organ-on-a-Chip via Cryopreservation of Cell-Loaded Microfluidic Chip Nanofiber (NF) membrane-integrated organ-on-a-chip platforms enhance in vitro tissue barrier models by mimicking in vivo microenvironments. However, their widespread adoption has been hindered by technical complexities such as manual cell seeding. In this study, we developed ReadyChip, a cryopreserved, preseeded NF membrane-integrated organ-on-a-chip that is immediately usable upon thawing. ReadyChip showed robust post-thaw performance by preserving both the structural characteristics and compositional properties of the ECM-coated NF membrane. Its versatility was demonstrated through vascular, retinal, and blood-brain barrier models, each showing post-thaw cellular viability above 92% and sustained expression of functional markers that remained expressed after 7 days of perfusion culture. By eliminating the need for manual seeding and complex culture processes, ReadyChip offers a ready-to-use platform that enhances efficiency and practicality in both biomedical research and industrial applications. Kim, Dohui; Yi, Soojin; Park, Byeong-ung; Lee, Seong Jin; Lee, Jeongmin; Kim, Dong Sung; Kim, Hong Kyun Pohang Univ Sci & Technol POSTECH, Dept Mech Engn, Pohang 37763, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Ophthalmol, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, Daegu 41944, South Korea; Pohang Univ Sci & Technol POSTECH, Dept Chem Engn, Pohang 37673, South Korea; Pohang Univ Sci & Technol POSTECH, Sch Interdisciplinary Biosci & Bioengn, Pohang 37673, South Korea; Yonsei Univ, Inst Convergence Res & Educ Adv Technol, Seoul 03722, South Korea; Kyungpook Natl Univ Hosp KNUH, Dept Ophthalmol, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp KNUH, Biomed Res Inst, Daegu 41940, South Korea Kim, Hong Kyun/ITT-7758-2023 57210428781; 56783537100; 57204502387; 57193437475; 59763199500; 59670675200; 59712573700 smkds@postech.ac.kr; okeye@knu.ac.kr; ACS MACRO LETTERS ACS MACRO LETT 2161-1653 14 5 SCIE POLYMER SCIENCE 2024 5.2 15.4 N/A 0 0 IN-VITRO; CULTURE Animals; Blood-Brain Barrier; Cell Survival; Cryopreservation; Humans; Lab-On-A-Chip Devices; Membranes, Artificial; Microphysiological Systems; Nanofibers; nanofiber; Barrier model; Cell seeding; Cryo-preservation; In-vitro; In-vivo; Microenvironments; Microfluidic-chips; Nanofiber membrane; Ready to use; Technical complexity; animal; artificial membrane; blood brain barrier; cell survival; chemistry; cryopreservation; devices; human; lab on a chip; organ on a chip; procedures; Nanosaws English 2025 2025-05-02 10.1021/acsmacrolett.5c00129 바로가기 바로가기 바로가기 바로가기
Article Relevance of Molecular Structure to the Morphological Properties of Lignin Extracted by Various Methods: X-ray Scattering Analysis Different extraction methods of separating lignin from biomass have resulted in considerable differences in the structure, purity, and properties of the material, which may affect its utilization and valorization. Differences in the lignin molecular structure also affect morphology, including size and structural rearrangement. Furthermore, knowledge of lignin morphology can help us understand its interfacial interactions with other materials. This study investigates the molecular structure, physicochemical characteristics, and morphological features of lignin samples obtained using various extraction processes, including milled wood lignin (MWL), organosolv lignin (OSL), softwood kraft lignin (SKL), and hardwood kraft lignin (HKL). The results indicate notable variations in structural units, total hydroxyl groups, and physicochemical properties among the various lignin samples. In particular, the larger amounts of oxygenated aliphatic linkages and aliphatic OH groups of MWL, along with its lower numbers of C-H aromatic bonds and higher molecular weight (M w) relative to the other types of lignin, result in a higher glass transition temperature (T g), a smaller radius of gyration (R g), and a higher fraction of T-shaped pi-pi stacking. Conversely, the fewer oxygenated aliphatic linkages, larger amounts of phenolic OH groups, and lower M w of OSL result in a relatively lower T g, higher R g, and greater fraction of sandwich-like pi-pi stacking. These properties of OSL, along with its good purity, make it more accessible than the other lignins for interactions or reactions with other materials. Wibowo, Eko Setio; Park, Byung-Dae; Koo, Bonwook; Shin, Yoon-Jung; Lee, Jae-Won Kyungpook Natl Univ, Dept Wood & Paper Sci, Daegu 41566, South Korea; Natl Res & Innovat Agcy, Res Ctr Biomass & Bioprod, Bogor 16911, Indonesia; Chonnam Natl Univ, Coll Agr & Life Sci, Dept Wood Sci & Engn, Gwangju 61186, South Korea; Chonnam Natl Univ, Interdisciplinary Program IT Bio Convergence Syst, Gwangju 61186, South Korea Park, Byung-Dae/ABB-1934-2020; Wibowo, Eko/AAL-5888-2021 57214910272; 59874304100; 59819643000; 57986043700; 7409622154 byungdae@knu.ac.kr; MACROMOLECULES MACROMOLECULES 0024-9297 1520-5835 58 8 SCIE POLYMER SCIENCE 2024 5.2 15.4 0 2025-05-07 0 0 ORGANOSOLV LIGNIN; KRAFT; VALORIZATION; DERIVATIVES; GIGANTEUS Anatomy; Hardwoods; Lignins; Molecular Structure; Radius Of Gyration; Softwoods; Stacking; Wood Products; Glass bonding; Physicochemical properties; Softwoods; Wood products; Extraction method; Large amounts; Morphological properties; Organosolv lignin; Property; Radius of gyration; Scattering analysis; Wood lignin; X -ray scattering; π-π- stacking; Hardwoods English 2025 2025-04-14 10.1021/acs.macromol.4c01922 바로가기 바로가기 바로가기 바로가기
Article Safety of the reduced fixed dose of mycophenolate mofetil confirmed via therapeutic drug monitoring in de novo kidney transplant recipients Background: Mycophenolate mofetil (MMF) is usually prescribed with a reduced fixed dose in Asian kidney transplant recipients (KTRs). However, the clinical efficacy and safety of the fixed dose have not yet been investigated via therapeutic drug monitoring. We evaluated whether reduced fixed-dose MMF is an optimal dosing strategy to achieve the therapeutic target of mycophenolic acid (MPA) exposure in Korean KTRs. Methods: This open-label, prospective study enrolled 50 de novo KTRs prescribed with tacrolimus, corticosteroid, and fixed-dose MMF (1.0-1.5 g/day). The trough level (C0) and area under the curve (AUC0-12 hr) of MPA were measured at 1 and 24 weeks after kidney transplantation (KT). The relationship of body weight (BW)-adjusted MMF dose with MPA C0 and MPA AUC0-12 hr was assessed using linear regression analysis. Results: The initial fixed dose of MMF of 1.44 +/- 0.16 g/day was adjusted in 24 patients (48.0%) and then reduced to a mean dose of 1.19 +/- 0.31 g/day at 24 weeks after KT. Most patients (>= 84.0%) attained the minimum required MPA C0 of 1.0 mu g/mL and MPA AUC0-12 hr of 30 mu g x hr/mL at 1 and 24 weeks. The BW-adjusted MMF dose demonstrated significant positive correlations with MPA C0 and MPA AUC0- 12 hr at 1 and 24 weeks after KT. Moreover, 14 patients (28.0%) reported MPA-related adverse events that were predictable based on MPA AUC0-12 hr (cutoff level, 46.4 mu g x hr/mL). Conclusion: The current reduced fixed-dose MMF strategy can help achieve the therapeutic target of MPA exposure in tacrolimus-treated Korean KTRs during the early posttransplant period. Jung, Hee-Yeon; Seo, Yu Jin; Hwang, Deokbi; Yun, Woo-Sung; Kim, Hyung-Kee; Huh, Seung; Yoo, Eun Sang; Lim, Jeong-Hoon; Choi, Ji-Young; Park, Sun-Hee; Kim, Yong-Lim; Il Won, Dong; Cho, Jang-Hee; Kim, Chan-Duck Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Stat, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Clin Pathol, Daegu, South Korea Kim, Hyung-Kee/JBR-8125-2023; Cho, Jang-hee/ABD-3534-2020; Lim, Jeong-Hoon/ABE-6003-2020; Jung, Hee-Yeon/AFB-8578-2022 57196396467; 59167627900; 57194422879; 35070717000; 35169819900; 7101832929; 7006609239; 55360244300; 7501393222; 7501831741; 55633533600; 7005166517; 7403536291; 59216189400 jh-cho@knu.ac.kr; drcdkim@knu.ac.kr; KIDNEY RESEARCH AND CLINICAL PRACTICE KIDNEY RES CLIN PRAC 2211-9132 2211-9140 44 1 SCIE UROLOGY & NEPHROLOGY 2024 3.8 15.4 0 2025-05-07 0 0 Area under curve; Kidney transplantation; Mycophenolate mofetil; Mycophenolic acid; Trough level ACUTE REJECTION; DOUBLE-BLIND; PHARMACOKINETICS; ACID; TACROLIMUS; PREVENTION; EXPOSURE; COMBINATION; STANDARD; EFFICACY Area under curve; Kidney transplantation; Mycophenolate mofetil; Mycophenolic acid; Trough level corticosteroid; folic acid; hemoglobin; interleukin 2; methylprednisolone; mycophenolate mofetil; mycophenolic acid; prednisolone; sulfamethoxazole; tacrolimus; thymocyte antibody; trimethoprim; adult; adverse event; anemia; Article; blood sampling; body mass; body weight; Cytomegalovirus; cytopenia; diabetes mellitus; diarrhea; drug monitoring; drug safety; estimated glomerular filtration rate; glomerulonephritis; human; kidney disease; kidney graft; kidney transplantation; leukocyte count; leukopenia; male; middle aged; polymerase chain reaction; prophylaxis; prospective study; sensitivity and specificity; thrombocytopenia English 2025 2025-01 10.23876/j.krcp.23.274 바로가기 바로가기 바로가기 바로가기
Article Vasopressin-Sensitive Aqp2 Regulation Mediated by the TAZ-NR4A1 Axis in Renal Collecting Duct Cells Regulation of aquaporin-2 (Aqp2) gene is essential for body water homeostasis. This study investigated how TAZ (a transcriptional coactivator with PDZ-binding motif, Wwtr1) controls vasopressin-driven AQP2 expression. AQP2 expression was studied using collecting duct-specific TAZ-knockout (TAZf/f; HoxB7Cre) mice and siRNA-mediated knockdown of TAZ in vasopressin-responsive mpkCCDc11 cells. Downstream factors of TAZ were identified using transcriptomics and bioinformatics. The TAZf/f; HoxB7Cre mice demonstrated polyuria and a significant decrease in AQP2 abundance in the kidney cortex and the outer medulla. dDAVP treatment (10-9 M, 24 h) on mpkCCDc11 cells significantly increased AQP2 mRNA and protein levels. However, siRNA-mediated TAZ knockdown (TAZ-KD) markedly attenuated these effects without affecting cAMP levels. Immunocytochemical analysis revealed a substantial decrease in AQP2 immunolabeling intensity in TAZ-KD cells following dDAVP stimulation. RNA sequencing analysis identified 1370 and 1985 differentially expressed genes in TAZ-KD cells under basal conditions and after dDAVP treatment, respectively. Among 17 previously identified transcription factor (TF) candidates, seven (Nr4a1, Cebpb, Mef2d, Elf3, Klf5, Junb, Stat3) were significantly upregulated by dDAVP in either control or TAZ-KD conditions. Among them, RT-qPCR analysis identified Nr4a1 as a TAZ-dependent TF, and immunoblotting revealed reduced NR4A1 protein levels in TAZ-KD cells upon dDAVP stimulation. This finding suggests its role as a TAZ-regulated target in dDAVP response pathway. Accordingly, Nr4a1-KD reduced the dDAVP-induced upregulation of Aqp2 mRNA and protein. KEGG pathway enrichment analysis revealed that HIF-1 signaling and glycolysis as central pathways affected by TAZ. TAZ-NR4A1 axis acts as a novel transcriptional regulatory mechanism in controlling vasopressin-mediated AQP2 expression. Choi, Hong Seok; Jang, Hyo-Ju; Kim, Wan-Young; Park, Sun Ah; Park, Euijung; Jung, Hyun Jun; Kwon, Tae-Hwan Kyungpook Natl Univ, Dept Biochem & Cell Biol, Taegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 FOUR KNU Convergence Educ Program, Taegu, South Korea; Ajou Univ, Sch Med, Dept Anat, Suwon, South Korea; Ajou Univ, Sch Med, Dept Neurol, Suwon, South Korea; Natl Heart Lung Blood Inst, NIH, Epithelial Syst Biol Lab, Syst Biol Ctr, Bethesda, MD 20892 USA; Johns Hopkins Univ, Sch Med, Dept Med, Div Nephrol, Baltimore, MD 21205 USA 58072531000; 57214330719; 59966965600; 57853536400; 50961544700; 59580991800; 7202206089 hjung24@jhmi.edu; thkwon@knu.ac.kr; FASEB JOURNAL FASEB J 0892-6638 1530-6860 39 13 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY;CELL BIOLOGY;BIOLOGY 2024 4.2 15.4 0 0 aquaporin-2; renal collecting duct; TAZ; transcription factor; vasopressin HIPPO SIGNALING PATHWAY; MESENCHYMAL TRANSITION; TRANSCRIPTION; TAZ; AQUAPORIN-2; EXPRESSION; FIBROSIS; YAP aquaporin-2; NR4A1; renal collecting duct; TAZ; transcription factor; vasopressin English 2025 2025-07-15 10.1096/fj.202500686rr 바로가기 바로가기 바로가기 바로가기
Article Impact of sirolimus on long-term adverse cardiovascular outcomes in kidney transplant recipients: A nationwide cohort study BackgroundKidney transplant recipients (KTRs) are at high risk for cardiovascular disease due to the long-term use of immunosuppressive therapy. This study aims to evaluate the long-term impact of sirolimus on cardiovascular outcomes in Korean KTRs.MethodsFrom a cohort of 7180 eligible KTRs identified from 2010 to 2021, 387 KTRs who received sirolimus were included. To control for confounding variables, propensity score matching was applied, and the landmark method was used to address immortal time bias. The primary outcome was major adverse cardiovascular events (MACE), defined as a composite of myocardial infarction, coronary revascularization, ischaemic stroke and all-cause mortality.ResultsThe analysis showed no significant difference in MACE between the sirolimus-treated and untreated groups (hazard ratio, 1.40; 95% confidence interval, .77-2.55), despite a higher incidence of dyslipidaemia in the sirolimus-treated group. However, subgroup analysis revealed an increased MACE risk in KTRs with pre-transplant congestive heart failure (CHF) who were treated with sirolimus (hazard ratio, 6.22; 95% confidence interval, 1.78-21.74), while no significant differences were found in other subgroups.ConclusionsThese findings suggest that while sirolimus can be a viable option for immunosuppression, it should be used cautiously in those with pre-existing CHF. Park, Jinhyun; Choi, Wonhui; Hwang, Jinseub; Jang, Ha Young; Kim, Yun; Ah, Young-Mi; Kwon, Jin-Won; Choi, Kyung Hee; Song, Yun-Kyoung Daegu Catholic Univ, Coll Pharm, Gyeongsan, South Africa; Daegu Univ, Dept Stat, Gyeongsan, Gyongsan, South Korea; Gachon Univ, Coll Pharm, Incheon, South Korea; Yeungnam Univ, Coll Pharm, Gyongsan, South Korea; Kyungpook Natl Univ, Coll Pharm, Based Intelligent Novel Drug Discovery Educ Unit B, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu, South Korea; Catholic Univ Korea, Coll Pharm, Bucheon, South Korea 59706240900; 59706241000; 59706032400; 57206894435; 57192988290; 25623061000; 16202951700; 57020443300; 56136407200 yksong@catholic.ac.kr; EUROPEAN JOURNAL OF CLINICAL INVESTIGATION EUR J CLIN INVEST 0014-2972 1365-2362 55 7 SCIE MEDICINE, GENERAL & INTERNAL;MEDICINE, RESEARCH & EXPERIMENTAL 2024 3.6 15.5 0 2025-05-07 0 0 adverse cardiovascular outcomes; kidney transplantation; mTOR inhibitors; Sirolimus CALCINEURIN INHIBITOR; RISK; EVEROLIMUS; CONVERSION; DISEASES; THERAPY; TARGET adverse cardiovascular outcomes; kidney transplantation; mTOR inhibitors; Sirolimus Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Dyslipidemias; Female; Graft Rejection; Heart Failure; Humans; Immunosuppressive Agents; Ischemic Stroke; Kidney Transplantation; Male; Middle Aged; Mortality; Myocardial Infarction; Myocardial Revascularization; Propensity Score; Proportional Hazards Models; Republic of Korea; Retrospective Studies; Sirolimus; Transplant Recipients; anticoagulant agent; antimetabolite; basiliximab; calcineurin inhibitor; corticosteroid; everolimus; immunoglobulin; mammalian target of rapamycin inhibitor; rituximab; sirolimus; thymocyte antibody; immunosuppressive agent; sirolimus; acute graft rejection; adult; all cause mortality; Article; cardiovascular disease; cohort analysis; congestive heart failure; controlled study; cumulative incidence; desensitization; dyslipidemia; female; graft recipient; health insurance; heart infarction; heart muscle revascularization; human; hypertension; ICD-10; immunosuppressive treatment; incidence; insurance; ischemic stroke; kidney allograft rejection; kidney transplantation; long term care; major clinical study; male; medical assistant; middle aged; plasmapheresis; prevalence; treatment duration; aged; cardiovascular disease; cause of death; epidemiology; graft recipient; graft rejection; heart failure; mortality; prevention and control; propensity score; proportional hazards model; retrospective study; South Korea English 2025 2025-07 10.1111/eci.70027 바로가기 바로가기 바로가기 바로가기
Article A Sovereign New Korea: North Korea's Postcolonial State Building, Women's Liberation, and Early Cold War Internationalism, 1945-1954 This research examines North Korea's equation of women's liberation to modernity and as an essential marker of independence and self-determination after colonial liberation in 1945. The Democratic Women's Union of the Democratic People's Republic of Korea (DPRK) functioned as both the discursive emblem of liberation and as a critical channel for internationalism. During the Korean War, this organization forged solidarity ties with what was then the world's largest international women's organization, the Women's International Democratic Federation, and stood at the forefront of a "New Korea." This study focuses on how North Korean women constituted an integral metonym of state integrity and authority vis-& agrave;-vis South Korea in the competition for postcolonial legitimacy between the DPRK and the Republic of Korea (ROK), as well as at the forefront of North Korea's dynamic internationalism that preceded a turn toward Third Wordism beginning in the mid-1950s. Hwang, Taejin Kyungpook Natl Univ, Daegu, South Korea 57203010719 hwangtj@knu.ac.kr; CRITICAL ASIAN STUDIES CRIT ASIAN STUD 1467-2715 1472-6033 57 2 SSCI AREA STUDIES 2024 1.4 15.7 0 2025-05-07 0 0 North Korea; North Korean Democratic Women's Union; Women's International Democratic Federation; Cold War; Postcolonial Korea MISSION; GENDER Cold War; North Korea; North Korean Democratic Women’s Union; Postcolonial Korea; Women’s International Democratic Federation North Korea; Cold War; nationalism; post-colonialism; self determination; social movement; state building; womens status English 2025 2025-04-03 10.1080/14672715.2025.2471574 바로가기 바로가기 바로가기 바로가기
Article Paper Visuo-tactile stimulated virtual mirror therapy (ViTaS-VMT) system for enhancing motor-related brain activities: Application on two amputees To enhance the degenerated brain signal of amputees on motor area, a visuo-tactile stimulated virtual mirror therapy system was developed. The system consists of a motion-tracking glove, a vibration motor, and a monitor-integrated table. The system can provide virtual hand illusion for body agency and combine visuo-tactile stimulation to induce body ownership on the virtual hand. The virtual hand then mimics the healthy hand like mirror therapy, and subjects perform grasping with both hands while observing the mirrored virtual hand on the amputated side. The training lasted three days, including the gradual exposure to the system to measure the difference in brain activity on the first day. We measured electroencephalogram (EEG) during training, and functional magnetic resonance imaging (fMRI) of grasping was measured before and after the training. Two amputees volunteered for this preliminary study. Both participants showed changes in motor-related brain activity, with consistent increases in event-related desynchronization (ERD) amplitude, particularly in the supplementary motor area (SMA) and primary motor cortex. These findings suggest the system's potential to enhance motor-related neural processes. We believe that the results of this preliminary study have provided evidence that the proposed system can reproduce the learning process and that brain activation can be improved by using the system. Based on the results, a future study will expand the number of subjects and the duration of training to provide a quantitative clinical evaluation of the proposed system. Song, Minsu; Jee, In-Hyeog; Kim, Seungho; Lee, Hansol; Lee, Hyun-Joo; Chu, Jun-Uk Univ British Columbia, Dept Psychol, Vancouver, BC V6T 1Z4, Canada; Korea Inst Machinery & Mat, Dept Med Device, Daegu 42994, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Med & Biol Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthopaed Surg, Daegu 41944, South Korea; Kyungpook Natl Univ, Med Device & Robot Inst, Daegu 41566, South Korea Song, Minsu/GSD-1521-2022 57189296126; 59723017500; 57218284791; 59299461900; 58838750100; 7402880919 lidmania@daum.net; juchu@kimm.re.kr; BIOCYBERNETICS AND BIOMEDICAL ENGINEERING BIOCYBERN BIOMED ENG 0208-5216 45 2 SCIE ENGINEERING, BIOMEDICAL 2024 6.6 15.7 0 2025-05-07 0 0 Brain-computer interface; Virtual hand illusion; Event-related desynchronization; Functional magnetic resonance imaging; BOLD signal COMPUTER INTERFACE; PARIETAL CORTEX; EEG; IMAGERY; MOVEMENT; HAND; REHABILITATION; SUPPLEMENTARY; CONNECTIVITY; ACTIVATION BOLD signal; Brain-computer interface; Event-related desynchronization; Functional magnetic resonance imaging; Virtual hand illusion action potential amplitude; arm amputee; Article; BOLD signal; brain function; clinical article; controlled study; echo planar imaging; electroencephalography; evoked response; exposure; functional magnetic resonance imaging; hand grip; hand movement; human; mirror therapy; preliminary data; primary motor cortex; supplementary motor area; T1 weighted imaging; tactile feedback; tactile stimulation; training; vibration; virtual reality; visual feedback; visual illusion; visual stimulation; visuo tactile stimulated virtual mirror therapy; visuomotor learning English 2025 2025 (APR-JUN) 10.1016/j.bbe.2025.03.005 바로가기 바로가기 바로가기 바로가기
Article A swarm intelligence approach to minimum weight independent dominating set problem The minimum weight independent dominating set (MWIDS) problem is a challenging problem in graph theory with diverse practical applications. In this paper, we propose a novel approach to tackle the MWIDS problem efficiently using the Artificial Bee Colony (ABC) algorithm, a metaheuristic optimization technique inspired by the foraging behavior of honeybees. Our approach integrates six heuristics tailored as per the characteristics of the MWIDS problem within the ABC algorithm to generate high-quality solutions by effectively exploring the solution space. We have conducted extensive experiments on standard benchmark instances to evaluate the effectiveness of our proposed approach. The experimental results demonstrate the competitiveness of our approach in comparison to the state-of-the-art for finding high quality solutions highlighting its potential for practical applications in real-world scenarios. Rasheed, Mohd Danish; Singh, Alok; Mallipeddi, Rammohan Univ Hyderabad, Sch Comp & Informat Sci, Hyderabad 500 046, Telangana, India; Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea ; Mallipeddi, Rammohan/AAL-5306-2020 59674512800; 35254330000; 25639919900 19mcpc03@uohyd.ac.in; alokcs@uohyd.ernet.in; mallipeddi@knu.ac.kr; COMPUTERS & ELECTRICAL ENGINEERING COMPUT ELECTR ENG 0045-7906 1879-0755 123 SCIE COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, ELECTRICAL & ELECTRONIC 2024 4.9 15.8 0 2025-05-07 1 1 Independent dominating set; Heuristic; Artificial bee colony algorithm; Swarm intelligence LOCAL SEARCH; ALGORITHM Artificial bee colony algorithm; Heuristic; Independent dominating set; Minimum weight independent dominating set; Swarm intelligence Optimization algorithms; Swarm intelligence; Artificial bee colony algorithm; Artificial bees; Bee colony algorithms; Dominating set problems; Heuristic; High-quality solutions; Independent dominating set; Minimum weight; Minimum weight independent dominating set; Weight independent dominating sets; Consensus algorithm English 2025 2025-04 10.1016/j.compeleceng.2025.110222 바로가기 바로가기 바로가기 바로가기
Article E-GAP: Evolutionary Gradient Attack on Privacy Collaborative learning, particularly in Federated Learning, has revolutionized the industry by enabling models to be trained collectively by a group while preserving participants' data privacy. Such networks operate by sharing only local updates with a global model, preventing direct exposure of raw data. However, vulnerabilities such as optimization-based gradient attacks have demonstrated the potential to reconstruct raw data from shared updates, exposing critical privacy risks and questioning the robustness of these frameworks. In this paper, we propose a privacy attack referred to as Evolutionary Gradient Attack on Privacy (E-GAP), an enhancement of the Recursive Gradient Attack on Privacy (R-GAP). E-GAP integrates Differential Evolution (DE) which belongs to the class of evolutionary algorithms, to optimize reconstructed gradients, diverging from traditional gradient descent approaches that rely on mean squared error (MSE). Since evolutionary approach allows us to examine the non-uniqueness of gradient weights, E-GAP not only improves reconstruction efficacy but also offers more profound insights into how these weights facilitate data reconstruction in weight-sharing networks. This study presents advances to an existing privacy attack, highlighting the inherent vulnerabilities of Federated Learning, and sheds light on the urgent need to reassess privacy safeguards in such frameworks. The implementation of E-GAP is publicly available at https://github.com/ yuvrajchaudhry/egap. Chaudhry, Yuvraj Singh; Mallipeddi, Rammohan Kyungpook Natl Univ, Daehak Ro, Daegu 41566, South Korea Mallipeddi, Rammohan/AAL-5306-2020 57219490571; 25639919900 yuvi.chaudhry@gmail.com; mallipeddi.ram@gmail.com; COMPUTERS & ELECTRICAL ENGINEERING COMPUT ELECTR ENG 0045-7906 1879-0755 124 SCIE COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, ELECTRICAL & ELECTRONIC 2024 4.9 15.8 N/A 0 0 Optimization; Federated learning; Differential evolution; Gradient attacks; Reconstruction DIFFERENTIAL EVOLUTION; OPTIMIZATION; MODEL Differential evolution; Federated learning; Gradient attacks; Optimization; Reconstruction Anonymity; Dynamic programming; Linear programming; Nonlinear programming; Sensitive data; Collaborative learning; Differential Evolution; Evolutionary gradients; Global models; Gradient attack; Gradient-descent; Optimisations; Privacy Attacks; Privacy risks; Reconstruction; Federated learning English 2025 2025-05 10.1016/j.compeleceng.2025.110399 바로가기 바로가기 바로가기 바로가기
Article Enhanced brain tumor classification using convolutional neural networks and ensemble voting classifier for improved diagnostic accuracy Brain tumors, characterized by abnormal cell growth within the brain and surrounding tissues, present significant clinical challenges. Early and accurate detection is essential for effective diagnosis, treatment planning, and improving patient outcomes. Magnetic resonance imaging (MRI) is the preferred modality for brain tumor detection due to its ability to produce high-quality images without ionizing radiation. This study addresses the need for accurate classification by leveraging three pre-trained convolutional neural network models - DenseNet-201, ResNet-101, and SqueezeNet - which enhance feature extraction and classification accuracy. The models were evaluated with and without K-fold cross-validation to ensure robust and reliable results. Additionally, implemented an ensemble voting classifier (EVC) to combine the strengths of the individual convolutional neural network (CNN) models, leading to improved accuracy and robustness. The models were tested on two datasets: (i) a binary dataset and (ii) a multi-class dataset, demonstrating the versatility of the approach. The ensemble classifier achieved 99.69% accuracy for multi-class data and 100% for binary data, outperforming individual models. Key metrics such as accuracy, sensitivity, specificity, precision, and F1-score were used to assess performance. These results highlight the effectiveness of ensemble learning for magnetic resonance imaging brain tumor classification, providing valuable insights for future research and potential clinical applications. Velpula, Vijaya Kumar; Vadlamudi, Jyothi Sri; Janapati, Malathi; Kasaraneni, Purna Prakash; Kumar, Yellapragada Venkata Pavan; Challa, Pradeep Reddy; Mallipeddi, Rammohan MLR Inst Technol, Dept Elect & Commun Engn, Hyderabad 500043, Telangana, India; Malla Reddy Engn Coll, Dept Elect & Commun Engn, Hyderabad 500100, Telangana, India; Siddhartha Acad Higher Educ, Dept Artificial Intelligence & Data Sci, Vijayawada 520007, Andhra Pradesh, India; Koneru Lakshmaiah Educ Fdn, Dept Comp Sci & Engn, Vaddeswaram 522502, Andhra Pradesh, India; VIT AP Univ, Sch Elect Engn, Amaravati 522237, Andhra Pradesh, India; Chandigarh Grp Coll, Mohali 140307, Punjab, India; Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 37224, South Korea Kasaraneni, Dr. Purna Prakash/GSJ-2169-2022; Y. V., Dr. Pavan Kumar/AHD-6564-2022; JANAPATI, MALATHI/KHW-9855-2024; Mallipeddi, Rammohan/AAL-5306-2020 58406727700; 59173829400; 59542345100; 57349252000; 54395950000; 57205482732; 25639919900 pavankumar.yv@vitap.ac.in; COMPUTERS & ELECTRICAL ENGINEERING COMPUT ELECTR ENG 0045-7906 1879-0755 123 SCIE COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, ELECTRICAL & ELECTRONIC 2024 4.9 15.8 0 2025-05-07 0 1 Brain tumor; Deep learning; DenseNet-201; Convolutional neural networks; Ensemble voting classifier; Magnetic resonance imaging (MRI); Multi-class classification; ResNet-101; SqueezeNet SEGMENTATION; FEATURES Brain tumor; Convolutional neural networks; Deep learning; DenseNet-201; Ensemble voting classifier; Magnetic resonance imaging (MRI); Multi-class classification; ResNet-101; SqueezeNet Deep neural networks; Diagnosis; Dynamic contrast enhanced MRI; Patient treatment; Brain tumors; Convolutional neural network; Deep learning; Densenet-201; Ensemble voting classifier; Magnetic resonance imaging; Multi-class classification; Resnet-101; Squeezenet; Voting classifiers; Clinical research English 2025 2025-04 10.1016/j.compeleceng.2025.110124 바로가기 바로가기 바로가기 바로가기
Article Prediction-guided multi-objective reinforcement learning with corner solution search Nowadays, several Reinforcement Learning (RL) tasks that feature conflicting objectives are being posed as multi-objective problems and consequently solved using dedicated Multi- Objective RL (MORL) algorithms. In MORL, the aim is to find several trade-off policies (Pareto optimal set) that optimize the featured objectives. To achieve this, several Evolutionary Multi- Objective optimization (EMO) schemes have been employed in the literature. Although it is well-established in the EMO community that the most important sub-tasks required to efficiently approximate the Pareto front (Pareto set in objective space) are those associated with the corner direction vectors, these sub-tasks are often not prioritized in most MORL schemes. Therefore in this paper, we propose a mechanism that prioritizes sub-tasks resulting from the corner direction weight vectors. Specifically, the sub-tasks are prioritized through a dynamic budget allocation scheme where higher budget allocations are assigned to the important sub-tasks in the initial stage of the evolution process. By so doing, the Pareto corner solutions can be approximated and contribute towards the effective realization of the optimal Pareto Front. The proposed scheme is incorporated into the Prediction Guided MORL algorithm (PGMORL) which is a high-performing evolutionary-based MORL Framework. Consequently, the resulting algorithm termed PGMORL with Corner Solution Search (csPGMORL) is favorably compared to the baseline PGMORL algorithm on five continuous robot locomotion control problems. Ajani, Oladayo S.; Fenyom, Ivan; Darlan, Daison; Mallipeddi, Rammohan Kyungpook Natl Univ, Daegu 41566, South Korea ; Mallipeddi, Rammohan/AAL-5306-2020; AJANI, Oladayo/HIR-9607-2022; Darlan, Daison/KQA-9542-2024 57465126000; 58655933000; 58164208500; 25639919900 oladayosolomon@gmail.com; ivanfenyom@gmail.com; daisondarlan33@gmail.com; mallipeddi.ram@gmail.com; COMPUTERS & ELECTRICAL ENGINEERING COMPUT ELECTR ENG 0045-7906 1879-0755 122 SCIE COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, ELECTRICAL & ELECTRONIC 2024 4.9 15.8 0 2025-05-07 0 0 Multi-objective reinforcement learning; Indicator-based evolutionary algorithm Indicator-based evolutionary algorithm; Multi-objective reinforcement learning Adversarial machine learning; Deep reinforcement learning; Federated learning; Reinforcement learning; Budget allocation; Evolutionary multiobjective optimization; Indicator-based evolutionary algorithm; Learning tasks; Multi objective; Multi-objective reinforcement learning; Pareto front; Reinforcement learnings; Solution searches; Subtask; Contrastive Learning English 2025 2025-03 10.1016/j.compeleceng.2024.109964 바로가기 바로가기 바로가기 바로가기
Article Takagi-Sugeno fractional-order interval type-2 fuzzy proportional-integral-derivative controller with real-time application to a magnetic levitation system This paper introduces a novel Takagi-Sugeno fractional-order interval type-2 fuzzy proportional- integral-derivative (TSFOIT2FPID) controller, addressing a critical gap in the literature. In sheer contrast to the existing Takagi-Sugeno integer-order interval type-2 fuzzy proportional-integral- derivative (TSIOIT2FPID) controllers, by incorporating the rich concept of fractional-order (FO) calculus, the proposed controller offers a more sophisticated control framework with additional tunable parameters. Due to the plant-model-free nature, intrinsically nonlinear dynamics, and the incorporation of footprints of uncertainty (FoUs) at the time of controller design, the proposed controller is well-suited for the control of complex, uncertain, and nonlinear systems, thereby overcoming the limitations associated with conventional and type-1 (T1) fuzzy proportional-integral-derivative (PID) controllers. Further, by excluding AND or OR operators from the mathematical modeling, the present approach allows independent tuning of the controller gains, thus enhancing the flexibility of the proposed control scheme. Apart from addressing the properties and computational aspects of the proposed controller, the superiority of the newly introduced controller over the existing conventional and fuzzy PID controllers is validated through rigorous hardware experiments on the magnetic levitation (MagLev) system, demonstrating its potential and usefulness for real-world control applications. Additionally, simulation results comparing the performance of the proposed controller and an FO integral-proportional-derivative (FOIPD) controller are also presented to offer a more thorough understanding of the effectiveness of the proposed control scheme. Sain, Debdoot; Praharaj, Manoranjan; Mohan, B. M.; Yang, Jung-Min Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehakro, Daegu 41566, South Korea; Indian Inst Technol Kharagpur, Dept Elect Engn, Kharagpur 721302, India Bosukonda, Murali/KLE-0140-2024; Sain, Debdoot/AAD-4709-2021 57192083193; 57224405027; 7006334785; 57208450551 saindebdoot@knu.ac.kr; praharaj@iitkgp.ac.in; mohan@ee.iitkgp.ac.in; jmyang@knu.ac.kr; COMPUTERS & ELECTRICAL ENGINEERING COMPUT ELECTR ENG 0045-7906 1879-0755 123 SCIE COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, ELECTRICAL & ELECTRONIC 2024 4.9 15.8 0 2025-05-07 1 1 Nonlinear PID controller; Takagi-Sugeno fuzzy controller; Interval type-2 fuzzy PID controller; Fractional-order PID controller; Mathematical modeling; Experimental validation PID CONTROLLER; STABILITY ANALYSIS; IMPLEMENTATION; PERFORMANCE; ALGORITHMS; FOOTPRINTS; DESIGN; MODEL Experimental validation; Fractional-order PID controller; Interval type-2 fuzzy PID controller; Mathematical modeling; Nonlinear PID controller; Takagi–Sugeno fuzzy controller Choquet integral; Fuzzy control; Integral equations; Levitation melting; Magnetic levitation; Magnetic levitation vehicles; Mathematical operators; Nonlinear control systems; Proportional control systems; Two term control systems; Experimental validations; Fractional order; Fractional-order proportional–integral–derivative controller; Fuzzy proportional integral derivative controller; Interval type-2 fuzzy; Interval type-2 fuzzy proportional–integral–derivative controller; Mathematical modeling; Nonlinear proportional integral; Nonlinear proportional–integral–derivative controller; Proportional-integral-derivatives controllers; Takagi-Sugeno fuzzy controllers; Three term control systems English 2025 2025-04 10.1016/j.compeleceng.2024.110001 바로가기 바로가기 바로가기 바로가기
Article A case study on the failure of the electrical panel of nuclear power plants by shaking table tests The clearest method to evaluate seismic performance is to test the equipment installed in nuclear power plants using shaking table tests. Accordingly, research is conducted to directly evaluate the seismic performance and limit state via shaking table tests on equipment identical to the specifications supplied to nuclear power plants. Specifically, the fragility level test through the actual equipment test, which primarily aims to investigate the equipment's critical acceleration and failure mode, was carried out. This paper summarizes the limit state of the electrical panel for a nuclear power plant observed via the shaking table test through the damage mode using an actual equipment test. The actual equipment test was performed to check the critical acceleration level and analyze the damage mode on the electrical panels to be tested. Results of the shaking table test on the electrical panel confirmed that functional abnormalities were attributed to shaking and impact. It was also found that functional abnormalities and structural failure can occur in earthquakes of similar magnitude. Moreover, structural failure observed mostly involves damage to the door lock, damage to and/or detachment of the internal parts, and damage to connecting members, usually concentrated in the components that support heavy parts. Jeon, Bub-Gyu; Park, Dong-Uk; Kim, Sung-Wan; Chang, Sung-Jin; Eem, Seunghyun; Park, Junhee Pusan Natl Univ, Seism Res & Test Ctr, 49 Busandaehak Ro, Yansan 50612, Gyeongnam, South Korea; Kyungpook Natl Univ, Dept Convergence & Fus Syst Engn, Major Plant Syst Engn, Sangju, South Korea; Korea Atom Energy Res Inst, Struct & Seism Safety Res Div, 111 Daedeok Daero 989 Beon Gil, Daejeon 34057, South Korea 54961482000; 56082144000; 55315467600; 55494267900; 52363442900; 36782938500 bkjeon79@pusan.ac.kr; swkin09@pusan.ac.kr; sjchang@pusan.ac.kr; NUCLEAR ENGINEERING AND TECHNOLOGY NUCL ENG TECHNOL 1738-5733 57 7 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2024 2.6 15.9 0 2025-05-07 0 0 Nuclear power plants; Electrical panel; Seismic performance; Shaking table tests; Failure mode Electrical panel; Failure mode; Nuclear power plants; Seismic performance; Shaking table tests English 2025 2025-07 10.1016/j.net.2025.103533 바로가기 바로가기 바로가기 바로가기
Article Assessing the effect of construction noise frequency on mental workload of construction workers with varying task difficulty using EEG data Noise pollution is a critical concern on construction sites because it adversely affects the cognitive performance of workers. While prior research has explored the effect of construction noise on workers' cognitive performance, gaps remain in understanding how these effects change under varying task difficulty and noise frequency. To address this limitation, this study investigates the combined effects of construction noise frequency and task difficulty on mental workload using EEG. To this end, a 3-level N-back memory task was conducted under three noise conditions while EEG data of participants was recorded simultaneously. Furthermore, behavioral and subjective data were collected. This study found that low-frequency noise has a more negative impact on mental workload. The frontal and left occipital-parietal brain regions show more responses to changes in mental workload. This study is expected to help in the development of mental workload assessment models and construction noise regulations for safety interventions. Olatunbosun, Samuel Oluwadamilare; Duorinaah, Francis Xavier; Haan, Chan-Hoon; Yi, Chang-Yong; Kim, Min-Koo Chungbuk Natl Univ, Fac Engn, Dept Architectural Engn, Chungbuk, South Korea; Chungbuk Natl Univ, Fac Engn, Dept Big Data, Chungbuk, South Korea; Kyungpook Natl Univ, Intelligent Construct Automat Ctr, Daegu, South Korea 59455876200; 59169134900; 55396018800; 36614886300; 57219442864 joekim@chungbuk.ac.kr; APPLIED ACOUSTICS APPL ACOUST 0003-682X 1872-910X 232 SCIE ACOUSTICS 2024 3.6 15.9 0 2025-05-07 1 1 Construction noise; Electroencephalography; Mental workload; Noise frequency; Task difficulty BAND POWER; PERFORMANCE; ALPHA; THETA; POTENTIALS; EXPOSURE; P300 Construction noise; Electroencephalography; Mental workload; Noise frequency; Task difficulty Cognitive performance; Combined effect; Construction noise; Construction sites; Construction workers; Mental workload; Noise frequencies; Performance gaps; Task difficulty; Workers'; Background noise English 2025 2025-03-15 10.1016/j.apacoust.2025.110571 바로가기 바로가기 바로가기 바로가기
Article Effects of Anxiety Focused Nursing Interventions on Anxiety, Cognitive Function and Delirium in Neurocritical Patients: A Non-Randomized Controlled Design Background Anxiety and cognitive dysfunction are common concerns in neurological intensive care units (ICUs) and are associated with adverse outcomes, including delirium. Addressing these issues effectively is crucial for improving patient outcomes and quality of care. Aim To develop an anxiety-focused nursing intervention programme and investigate the effects of this programme on anxiety levels, cognitive function and the incidence of delirium among patients in a neurological ICU. Study Design A non-randomized controlled design was employed. Method The outcome variables of experimental and control groups were compared. Sixty patients in a 1235-bed tertiary general hospital ICU in South Korea were assigned to the experimental (n = 30) or control group (n = 30), which were administered the anxiety nursing intervention and standard care, respectively. Anxiety and cognitive function were measured before and after the intervention, while the incidence of delirium was monitored throughout the study period. Results The results showed that the experimental group exhibited significantly lower anxiety levels (t = 6.83, p < 0.001) and improved cognitive function (t = 2.56, p = 0.013) compared to that of the control group. Additionally, the incidence of delirium in the experimental group was significantly reduced (chi(2) = 11.28, p = 0.001) post-intervention. Conclusions The anxiety nursing intervention programme effectively reduces anxiety, improves cognitive function and decreases the incidence of delirium in patients with neurocritical conditions. Relevance to Clinical Practice These findings highlight the essential role of comprehensive nursing interventions in addressing the psychological and cognitive needs of patients with neurocritical conditions. Training nurses to implement the developed protocol is vital to improve patient outcomes in neurological intensive care settings. Jang, Seo-young; Lee, Myung Kyung Kyungpook Natl Univ, Grad Sch Forens & Invest Sci, Dept Forens Nursing, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Nursing Innovat, Coll Nursing, Daegu, South Korea 59909965100; 40661513200 mlee@knu.ac.kr; NURSING IN CRITICAL CARE NURS CRIT CARE 1362-1017 1478-5153 30 3 SCIE;SSCI NURSING 2024 2.6 15.9 0 2025-06-11 0 0 anxiety; cognitive function; incidence of delirium; neurocritical care; nursing intervention programme; patients in intensive care unit INTENSIVE-CARE-UNIT; CRITICAL ILLNESS; RELIABILITY; VALIDITY; SCALE anxiety; cognitive function; incidence of delirium; neurocritical care; nursing intervention programme; patients in intensive care unit Adult; Aged; Anxiety; Cognition; Critical Care Nursing; Delirium; Female; Humans; Incidence; Intensive Care Units; Male; Middle Aged; Republic of Korea; adult; aged; anxiety; cognition; delirium; epidemiology; female; human; incidence; intensive care nursing; intensive care unit; male; middle aged; prevention and control; procedures; South Korea English 2025 2025-05 10.1111/nicc.70062 바로가기 바로가기 바로가기 바로가기
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