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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Unveiling environmental drivers of soil erosion in South Korea through SHAP-informed machine learning | Soil erosion remains a critical environmental issue in South Korea due to its mountainous terrain and variable climatic conditions, adversely affecting agriculture, water quality, and infrastructure. While the Revised Universal Soil Loss Equation (RUSLE) is widely used for large-scale assessments, its limitations in scalability and capturing complex environmental interactions in diverse landscapes persist. Machine learning (ML) techniques offer a promising alternative by handling large datasets and modeling non-linear relationships, yet their 'black box' nature often hinders interpretability, which is essential for practical applications in soil conservation. This study addresses these challenges by applying six ML algorithms-Random forests (RF), Support vector machines (SVM), AdaBoost (AB), Logistic regression (LR), K-nearest neighbors (KNN), and Multi-layer perceptron (MLP)- to develop soil erosion susceptibility maps (SESM) across South Korea. Using the RUSLE model for preliminary identification and combined with high-resolution satellite images, we assigned erosion-prone areas to serve as the training data for our analysis. Thirteen key environmental factors were considered. To enhance the interpretability of the ML models, we integrated SHapley Additive exPlanations (SHAP), a method to attribute predictions to individual features, to enhance ML model interpretability. Our results indicate that the RF and SVM models achieved the highest predictive accuracy. SHAP analysis revealed that slope and land cover were the most influential in predicting SESM. This approach bridges advanced modeling techniques and practical applicability, enabling targeted soil conservation strategies in South Korea and offering a scalable framework for other erosionprone regions. | Van, Linh Nguyen; Nguyen, Giang, V; Yeon, Minho; Do, May Thi-Tuyet; Lee, Giha | Kyungpook Natl Univ, Sch Adv Sci & Technol Convergence, Sangju 37224, South Korea; Kyungpook Natl Univ, Climate Crisis Inst, Sangju 37224, South Korea | 58045719400; 57297771000; 57223436971; 59786143700; 35069799400 | leegiha@knu.ac.kr; | LAND USE POLICY | LAND USE POLICY | 0264-8377 | 1873-5754 | 155 | SSCI | ENVIRONMENTAL STUDIES | 2024 | 5.9 | 14.9 | N/A | 0 | 0 | Soil erosion; Machine learning; SHAP; Land use policy; South Korea | LOGISTIC-REGRESSION; LAND; SUSCEPTIBILITY; MODELS; COVER; RUSLE | Land use policy; Machine learning; SHAP; Soil erosion; South Korea | South Korea; image resolution; land use change; machine learning; satellite imagery; soil conservation; soil erosion | English | 2025 | 2025-08 | 10.1016/j.landusepol.2025.107592 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | 3,6-Anhydro-L-galactose suppresses mouse lymphocyte proliferation by attenuating JAK-STAT growth factor signal transduction and G1-S cell cycle progression | Recombinant GH16B (3-agarase-catalyzed liquefaction of 5-7 %(w/v) melted agarose at 50 degrees C completely hydrolyzed agarose into neoagarohexaose (NA6) and neoagarotetraose (NA4). Subsequent saccharification by recombinant GH50A (3-agarase or recombinant GH50A (3-agarase/recombinant GH117A alpha-neoagarobiose hydrolase at 35 degrees C converted NA6/NA4 into neoagarobiose (NA2) or 3,6-anhydro-L-galactose (L-AHG)/D-galactose, respectively. Purification of NA6/NA4 and NA2 was achieved by Sephadex G-15 column chromatography, while L-AHG was purified by Sephadex G-10, achieving >= 98 % purity. L-AHG (25-200 mu g/mL), but not NA2, NA4, or NA6, inhibited the proliferation of immobilized anti-CD3/anti-CD28-activated T cells and immobilized antiCD40 + soluble anti-IgM + interleukin (IL)-4-activated B cells. This inhibition impacted the G1-S traverse in the cell cycle without influencing CD69 expression and p27Kip1 down-regulation, markers of the exit from G0 into G1 phase in activated lymphocytes. L-AHG impeded cyclin-dependent kinases (CDKs)-driven retinoblastoma phosphorylation, necessary for the G1-S traverse, by reducing the activating phosphorylation of CDKs (CDK4, CDK2, and CDK1) and lowering cyclin D3, cyclin A2 and cyclin B1 levels. Furthermore, L-AHG diminished the production of growth factors, including IL-2 in activated T cells and IL-6 in activated B cells. The antiproliferative effect of L-AHG on T cells was partially restored by exogenous IL-2 but was unaffected by exogenous IL-6 on B cells. L-AHG inhibited the activating phosphorylation of Janus kinase 1 (JAK1), affecting signal transducer and activator of transcription 1 (STAT1) and STAT3 signaling. These results demonstrate that L-AHG may serve as a novel immunosuppressant by impairing JAK-STAT growth factor signaling and G1-S cell cycle progression in T and B lymphocytes. | Park, Shin Young; Kim, Ki Yun; Jang, Won Young; Bae, Young-Seuk; Jun, Do Youn; Kim, Young Ho | Kyungpook Natl Univ, AT BIO Inc 31, Business Incubat Ctr 403, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Sch Life Sci & Biotechnol, Lab Immunobiol, 80 Daehak Ro, Daegu 41566, South Korea | 57210165477; 57189898278; 56373427000; 59498032900; 19134667600; 57208312159 | ykim@knu.ac.kr; | INTERNATIONAL IMMUNOPHARMACOLOGY | INT IMMUNOPHARMACOL | 1567-5769 | 1878-1705 | 147 | SCIE | IMMUNOLOGY;PHARMACOLOGY & PHARMACY | 2024 | 4.7 | 15.2 | 0 | 2025-05-07 | 0 | 0 | 6-Anhydro-L-galactose; Enzymatic agarose hydrolysis; JAK-STAT signaling; Immunosuppressant; Lymphocyte proliferation inhibitor; Retardation of G1-S progression | T-CELLS; ACTIVATION; PHOSPHORYLATION; EXPRESSION; PROTEIN; INTERLEUKIN-2; APOPTOSIS; SURVIVAL; KINASE; XENOTRANSPLANTATION | 3,6-Anhydro-L-galactose; Enzymatic agarose hydrolysis; Immunosuppressant; JAK-STAT signaling; Lymphocyte proliferation inhibitor; Retardation of G<sub>1</sub>-S progression | Animals; B-Lymphocytes; Cell Proliferation; Galactose; Janus Kinases; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Signal Transduction; STAT Transcription Factors; T-Lymphocytes; agarose; cyclin A2; cyclin B1; cyclin D3; cyclin dependent kinase; galactose; interleukin 2; interleukin 4; interleukin 6; Janus kinase 1; oclacitinib; OKT 3; selicrelumab; sephadex; STAT1 protein; STAT3 protein; galactose; Janus kinase; STAT protein; animal cell; animal experiment; antiproliferative activity; Article; cell cycle progression; cell lysate; cell proliferation assay; column chromatography; controlled study; down regulation; electrospray mass spectrometry; enzymatic degradation; enzyme linked immunosorbent assay; flow cytometry; genetic recombination; human; human cell; hydrolysis; JAK-STAT signaling; kinetics; liquefaction; lymphocyte proliferation; male; mouse; nonhuman; protein phosphorylation; retinoblastoma; saccharification; signal transduction; Western blotting; animal; B lymphocyte; Bagg albino mouse; cell proliferation; drug effect; immunology; lymphocyte activation; metabolism; T lymphocyte | English | 2025 | 2025-02-06 | 10.1016/j.intimp.2024.113998 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches | Purpose: This study investigated asthma phenotypes and their associations with ventilation heterogeneity and particle deposition by utilizing Single-Photon Emission Computed Tomography (SPECT) imaging, quantitative Computed Tomography (qCT) imaging-based subgrouping, and a whole-lung computational model. Materials and methods: Two datasets were analyzed: one from a combined SPECT and CT (SPECT/CT) study with six asthmatic subjects, and another from the Severe Asthma Research Program (SARP) with 209 asthmatic subjects. Data from 35 previously acquired healthy subjects served as a control group. Each subject underwent CT scans at full inspiration and expiration, along with pulmonary function testing (PFT). The SPECT/CT study included ventilation SPECT imaging. Key qCT variables such as airway diameter, wall thickness, percentage of air trapping (AirT%), and percentage of small airway disease (fSAD%) were assessed. A subject-specific whole-lung computational fluid and particle dynamics (CFPD) model predicted airway resistance, particle deposition fraction, and the coefficient of variation (CV) for ventilation heterogeneity. Subjects were categorized into four predefined asthma imaging subgroups/clusters with increasing severity (C1-C4). CFPD-predicted CVs werevalidated against SPECT measurements. We compared PFT, qCT, and CFPD variables across SARP clusters and analyzed particle deposition fractions in large conducting, small conducting, and respiratory airways. Results: Cluster C4 exhibited a significantly distinct ventilation profile compared to other clusters and health controls. This distinction contrasted with the insignificant differences between ventilation profiles in severity subgroups defined by conventional spirometry-based guidelines. Airway resistance varied significantly across the asthma clusters. Although both C3 and C4 clusters represented severe asthma, only C4 showed a significant increase in AirT%, primarily due to fSAD%. Since inflammatory phenotypes differ - C3 with wall thickening in large and small conducting airways, and C4 with elevated fSAD% and Emph% in small conducting and respiratory airways - fine particles (similar to 5 mu m) and extrafine particles (similar to 1 mu m) are more effective at reaching the respective regions in C3 and C4. Given that C2 and C4 have hyper-responsive phenotypes with narrowed conducting airways, fine particles are more effective in reaching these areas. Airway enlargement in targeted segments of the left lower lobe resulted in improved particle deposition. Conclusion: Our cluster-informed CFPD-based approach enhances the understanding of ventilation heterogeneity in asthma and holds potential for refining strategies for inhalational therapies. | Zhang, Xuan; Rajaraman, Prathish K.; Li, Frank; Choi, Sanghun; Comellas, Alejandro P.; Hoffman, Eric A.; Fain, Sean B.; Kaczka, David W.; Smith, Benjamin M.; Choi, Jiwoong; Castro, Mario; Wenzel, Sally E.; Jarjour, Nizar N.; Schiebler, Mark L.; Israel, Elliot; Levy, Bruce D.; Fahy, John V.; Erzurum, Serpil C.; Babiskin, Andrew; Kinjo, Minori; Walenga, Ross; Lin, Ching-Long | Univ Iowa, IIHR Hydrosci & Engn, Iowa City, IA 52242 USA; Univ Iowa, Dept Mech Engn, Iowa City, IA USA; Univ Iowa, Roy J Carver Dept Biomed Engn, Iowa City, IA USA; Kyungpook Natl Univ, Sch Mech Engn, Daegu, South Korea; Univ Iowa, Dept Internal Med, Iowa City, IA USA; Univ Iowa, Dept Radiol, Iowa City, IA USA; Univ Iowa, Dept Elect & Comp Engn, Iowa City, IA USA; Univ Iowa, Dept Hlth & Human Physiol, Iowa City, IA USA; Univ Iowa, Dept Anesthesia, Iowa City, IA USA; Univ Iowa, Dept Radiol, Iowa City, IA USA; Columbia Univ, Coll Phys & Surg, Dept Med, New York, NY USA; McGill Univ, Dept Med, Hlth Ctr, Res Inst, Montreal, PQ, Canada; Univ Kansas, Div Pulm Crit Care & Sleep Med, Sch Med, Kansas City, KS USA; Univ Pittsburgh, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA USA; Univ Wisconsin, Sch Med & Publ Hlth, Madison, WI USA; Harvard Med Sch, Brigham & Womens Hosp, Boston, MA USA; Univ Calif San Francisco, Dept Med, San Francisco, CA USA; Cleveland Clin, Cleveland, OH USA; US FDA, Ctr Drug Evaluat & Res, Div Quantitat Methods & Modeling, Off Res & Stand,Off Gener Drugs, Silver Spring, MD USA; US FDA, Div Therapeut Performance 2, Off Res & Stand, Off Gener Drugs,Ctr Drug Evaluat & Res, Silver Spring, MD USA | ; Kaczka, David/A-2984-2008; Fahy, John/ABS-1213-2022; Fain, Sean/K-4260-2016; Comellas, Alejandro/AAE-5661-2019; Schiebler, Mark/V-5201-2019 | 57841130800; 59266216700; 57222179446; 55847101000; 6603070104; 58000586800; 7007034729; 6701665191; 55476100800; 55749525100; 7402292535; 7101833061; 7003501462; 7003277933; 25960102600; 7401702499; 7006313500; 7005108319; 56646371200; 57194855600; 51261570200; 8923593300 | ching-long-lin@uiowa.edu; | EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | EUR J PHARM SCI | 0928-0987 | 1879-0720 | 209 | SCIE | PHARMACOLOGY & PHARMACY | 2024 | 4.7 | 15.2 | 0 | 2025-05-07 | 0 | 0 | Asthma; CT; SPECT; Clusters; CFPD; Ventilation heterogeneity; Particle deposition | BRONCHIAL THERMOPLASTY; IMPULSE OSCILLOMETRY; AEROSOL DEPOSITION; LUNG; DISEASE; MULTICENTER; GUIDELINES; MANAGEMENT; HEALTHY; AIRWAYS | Asthma; CFPD; Clusters; CT; Particle deposition; SPECT; Ventilation heterogeneity | Adult; Asthma; Computer Simulation; Female; Humans; Lung; Male; Middle Aged; Pulmonary Ventilation; Respiratory Function Tests; Single Photon Emission Computed Tomography Computed Tomography; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Young Adult; bronchodilating agent; technetium sulfur colloid tc 99m; adult; airway; airway resistance; Article; asthma; cohort analysis; comparative study; computer assisted tomography; computer model; controlled study; exhalation; female; human; inhalation; lung deposit; lung function test; lung ventilation; major clinical study; male; particulate matter; phenotype; quantitative analysis; severe asthma; single photon emission computed tomography-computed tomography; small airway disease; spirometry; thickness; computer simulation; diagnostic imaging; lung; lung ventilation; middle aged; pathophysiology; single photon emission computed tomography; single photon emission computed tomography-computed tomography; x-ray computed tomography; young adult | English | 2025 | 2025-06-01 | 10.1016/j.ejps.2025.107093 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Correction | Continentalic acid exhibited nephroprotective activity against the LPS and E. coli-induced kidney injury through inhibition of the oxidative stress and inflammation ( vol 80, 106209, 2020) | Khan, Amir Muhammad; Khan, Ashraf Ullah; Ali, Hussain; Ul Islam, Salman; Seo, Eun Kyoung; Khan, Salman | Quaid I Azam Univ, Fac Biol Sci, Dept Pharm, Islamabad 45320, Pakistan; Kyungpook Natl Univ, Coll Nat Sci, Sch Life Sci, Daegu 41566, South Korea; Ewha Womans Univ, Coll Pharm, 52 Ewhayeodae Gil, Seoul 03760, South Korea | 57214230785; 57200756218; 56003879200; 56985186700; 7005953758; 58961283100 | skhan@qau.edu.pk; | INTERNATIONAL IMMUNOPHARMACOLOGY | INT IMMUNOPHARMACOL | 1567-5769 | 1878-1705 | 148 | SCIE | IMMUNOLOGY;PHARMACOLOGY & PHARMACY | 2024 | 4.7 | 15.2 | 0 | 2025-05-07 | 0 | 0 | erratum; human; nonhuman | English | 2025 | 2025-02-20 | 10.1016/j.intimp.2025.114160 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | Article | Risk factors for urinary retention after robot-assisted radical cystectomy with orthotopic neobladder diversion: a multicenter study | To determine risk factors for urinary retention (UR) after robot-assisted radical cystectomy (RALC) with orthotopic neobladder diversion. A total of 269 patients who underwent RALC with orthotopic neobladder diversion from 2008 to 2019 at seven tertiary hospitals were retrospectively analyzed. There were 68 patients who had UR (UR arm) and 201 patients who did not have UR (no-UR arm). UR was defined as voiding dysfunction without catheterization or more than 100 mL of residual urine after voiding. Preoperative demographics, perioperative factors, pathology outcomes, and postoperative complications of UR and no-UR arms were compared and predictors of UR were identified. Among demographic factors, only gender proportion showed a difference, with male proportion being significantly lower in the UR arm than in the no-UR arm (81% vs 92%, p = 0.010). For perioperative outcomes, anastomosis site stricture (27% vs 11%, p = 0.003) and length of hospital stays (23 days vs. 19 days, p = 0.001) were significantly higher in the UR arm than in the no-UR arm. In multiple logistic regression analysis, female (OR 3.32, 95% CI: 1.43–7.72) and body mass index (BMI) (OR 1.10, 95% CI 1.00–1.20) were UR predictors. UR after RALC with orthotopic neobladder diversion is significantly increased in females. Multiple logistic regression analysis identified female and BMI elevation as UR predictors. © The Author(s) 2024. | Chung, Younsoo; Lee, Sangchul; Jeong, Byong Chang; Ku, Ja Hyeon; Kwon, Tae Gyun; Kim, Tae-Hwan; Lee, Ji Youl; Hong, Sung Hoo; Han, Woong Kyu; Ham, Won Sik; Kang, Sung Gu; Kang, Seok Ho; Oh, Jong Jin | Department of Urology, Seoul National University Bundang Hospital, Seongnam, South Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, South Korea, Department of Urology, Seoul National University College of Medicine, Seoul, South Korea; Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Urology, Seoul National University College of Medicine, Seoul, South Korea; Department of Urology, Kyungpook National University School of Medicine, Daegu, South Korea; Department of Urology, Kyungpook National University School of Medicine, Daegu, South Korea; Department of Urology, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea; Department of Urology, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea; Department of Urology, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; Department of Urology, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; Department of Urology, Korea University College of Medicine, Seoul, South Korea; Department of Urology, Korea University College of Medicine, Seoul, South Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, South Korea, Department of Urology, Seoul National University College of Medicine, Seoul, South Korea, Building1 7th floor Urology office, 300-0, Bundang-Gu, Gyeonggi-Do, Seongnam-si, South Korea | 57215536028; 57202327303; 7102237943; 36800523000; 15073765400; 57797823600; 57202074202; 37030299600; 7401899857; 57283367700; 35995660400; 7405684686; 24468588100 | urojin@snu.ac.kr; | Journal of Robotic Surgery | J ROBOT SURG | 1863-2483 | 1863-2491 | 19 | 1 | SCIE | SURGERY | 2024 | 3 | 15.2 | 0 | 2025-05-07 | 0 | Bladder cancer; Body mass index; Female; Urination; Urination disorder | Aged; Body Mass Index; Cystectomy; Female; Humans; Length of Stay; Male; Middle Aged; Postoperative Complications; Retrospective Studies; Risk Factors; Robotic Surgical Procedures; Sex Factors; Urinary Bladder Neoplasms; Urinary Diversion; Urinary Retention; Diseases; Microrobots; Risk assessment; Robotic arms; Urology; Bladder cancers; Body mass; Body mass index; Female; Mass index; Orthotopic; Radical cystectomy; Urinary retention; Urination; Urination disorder; abdominal surgery; adult; anastomosis; Article; biopsy; bladder cancer; bladder reconstruction; body mass; catheterization; controlled study; extracorporeal therapy; female; follow up; hospitalization; human; human tissue; length of stay; logistic regression analysis; major clinical study; male; micturition; micturition disorder; middle aged; multicenter study; neoadjuvant therapy; orthotopic neobladder diversion; outcome assessment; perioperative monitoring; peritonitis; postoperative complication; preoperative evaluation; prostatectomy; residual urine; retrospective study; risk factor; robot-assisted radical cystectomy; sex difference; urethra stenosis; urine incontinence; urine retention; adverse event; aged; bladder tumor; clinical trial; cystectomy; epidemiology; etiology; postoperative complication; procedures; risk factor; robot assisted surgery; sex factor; surgery; urinary diversion; urine retention; Logistic regression | English | Final | 2025 | 10.1007/s11701-024-02099-y | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Sustainable-biomass-derived multifunctional carbon dots as fluorescent probes for multi-purpose advanced imaging, migration and security solutions | Multifunctional tunable-emissive carbon dots (ME-CDs) were hydrothermally synthesized and characterized for their structural, morphological, and optical properties, as well as their applications in biological imaging and anti-counterfeiting. Scanning electron microscopy revealed uniformly dispersed wrinkle-shaped particles, while high-resolution transmission electron microscopy confirmed sizes below 5 nm. Energy-dispersive X-ray spectroscopy and X-ray photoelectron spectroscopy validated the carbon-dominant composition, with functional groups essential for biological interactions. Raman spectroscopy showed a partially disordered graphite-like structure with a 0.72 D/G intensity ratio, and Fourier-transform infrared spectroscopy identified surface functionalities. The UV-vis absorption spectrum exhibited characteristic pi-pi* and n-pi* transitions at 280 nm and 340 nm, while fluorescence studies demonstrated strong excitation-dependent emission suitable for imaging. ME-CDs showed remarkable stability, maintaining fluorescence intensity over 200 days and under UV irradiation. As fluorescent ink, they displayed clear visibility under UV light and prolonged durability. Biocompatibility studies confirmed non-toxicity, enabling effective labeling of fibroblasts and human mesenchymal stem cells (HMSCs) with confocal visualization. ME-CDs also penetrated 3D HMSC spheroids, providing multicolor fluorescence without affecting cell viability, and efficiently tracked macrophage migration. The robust optical properties, biocompatibility, and durability of ME-CDs underscore their potential for long-term applications in bioimaging and anti-counterfeiting. | Atchudan, Raji; Karuppasamy, Bavya Devi; Perumal, Suguna; Gangadaran, Prakash; Sundramoorthy, Ashok K.; Manoj, Devaraj; Rajendran, Ramya Lakshmi; Ahn, Byeong-Cheol; Ahamed, Maqusood; Lee, Seung Woo; Lee, Yong Rok | Yeungnam Univ, Sch Chem Engn, Gyongsan 38541, South Korea; KPR Inst Engn & Technol, Ctr Res & Dev, Dept Chem, Coimbatore 641407, Tamil Nadu, India; Sejong Univ, Dept Chem, Seoul 143747, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 FOUR KNU Convergence Educ Program Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Daegu 41944, South Korea; Saveetha Dent Coll & Hosp, Saveetha Inst Med & Tech Sci, Dept Prosthodont, Poonamallee High Rd, Chennai 600077, Tamil Nadu, India; Karpagam Acad Higher Educ, Dept Chem, Coimbatore 641021, Tamil Nadu, India; Karpagam Acad Higher Educ, Ctr Mat Chem, Coimbatore 641021, Tamil Nadu, India; King Saud Univ, King Abdullah Inst Nanotechnol, Riyadh 11451, Saudi Arabia | ; Rajendran, Ramya/AAV-6338-2021; RAJI, ATCHUDAN/C-9904-2017; Ahamed, Maqusood/R-8619-2017; Gangadaran, Prakash/AAV-3102-2021; Sundramoorthy, Ashok K./AAD-2476-2022; Manoj, Devaraj/N-6903-2019; perumal, suguna/N-9075-2017 | 26648054700; 58925883500; 56673798900; 54393130400; 55372506600; 49961897200; 57195318729; 7202791511; 15041853700; 57211365101; 57330662900 | atchudanr@yu.ac.kr; leesw1212@ynu.ac.kr; yrlee@yu.ac.kr; | SURFACES AND INTERFACES | SURF INTERFACES | 2468-0230 | 62 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, COATINGS & FILMS;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 6.3 | 15.2 | 0 | 2025-05-07 | 2 | 2 | Hydrothermal method; Multifunctional carbon dot; Tunable-emission; Fluorescent ink; Anti-counterfeiting; Cell migration imaging | CONVERSION | Anti-counterfeiting; Cell migration imaging; Fluorescent ink; Hydrothermal method; Multifunctional carbon dot; Tunable-emission | English | 2025 | 2025-04-01 | 10.1016/j.surfin.2025.106238 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Synergistic enhancement of crosslinked cellulose nanofiber-lignin composite films toward sustainable biobased materials | The increasing demand for alternatives to petroleum-based films has spurred the quest for high-performance degradable materials. Cellulose, a natural polymer, emerges as an excellent candidate to meet this demand. The development of cellulose films is advanced through crosslinking and additive incorporation. Lignin, a wood by-product with versatile functionalities, serves as a valuable additive. This study explored the synergistic effects of crosslinking cellulose nanofiber (CNF) and lignin. First, non-crosslinked composite films with varying lignin concentrations (NCC-L1, NCC-L5, and NCC-L10) were prepared through solvent casting. Subsequently, the films were immersed in a glutaraldehyde solution with acid catalysts, yielding crosslinked CNF-lignin composite films (GACC-L1, GACC-L5, and GACC-L10). The crosslinking process introduced strong acetal bonds, augmenting the inherent hydrogen bonds of the non-crosslinked films. The results demonstrated that crosslinking significantly enhanced the mechanical properties, thermal stability, crystallinity, and water resistance of the films. Additionally, the integration of lignin conferred UV-blocking and antibacterial properties to the crosslinked films. Notably, GACC-L10 demonstrated superior characteristics, including elevated strength (54.32 MPa), the highest T-max (324.53 degrees C), remarkable antibacterial efficacy (99.9 %), and exceptional transparency (similar to 90 % at 800 nm). Consequently, these films hold promise for a wide range of applications, contributing to the advancement of sustainable materials across diverse industries. | Jang, Sunjin; Kim, Bo Min; Choi, Jin Sil; Park, Jaehyeon; Lee, Jihoon; Lee, Seung Yeol; Park, Jaehyeung | Kyungpook Natl Univ, Dept Carbon & Fiber Composite Mat, Daegu 41566, South Korea; Hyundai Motor Grp, Interior & Exterior Mat Dev Team, Hwaseong 18280, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Dept Plant Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Biofibers & Biomat Sci, Daegu 41566, South Korea | Choi, Jin-sil/AAD-1076-2021 | 57191615594; 58641148700; 58512402700; 58745582800; 59338387300; 59510735800; 55566554000 | parkj@knu.ac.kr; | SURFACES AND INTERFACES | SURF INTERFACES | 2468-0230 | 64 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, COATINGS & FILMS;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 6.3 | 15.2 | 0 | 2025-05-07 | 0 | 0 | Cellulose nanofiber; Lignin; Crosslinking; Biomass; Composite | HIGH RESIDUAL LIGNIN; ZNO NANOPARTICLES; CHITOSAN; GLUTARALDEHYDE; ANTIOXIDANT; PRETREATMENT; PERFORMANCE | Biomass; Cellulose nanofiber; Composite; Crosslinking; Lignin | English | 2025 | 2025-05-01 | 10.1016/j.surfin.2025.106369 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | An Analog-Filtered OFDMA Design for Receivers Utilizing One-Bit ADCs in Wideband Channels | One-bit analog-to-digital converters (ADCs), despite introducing non-linear distortion, achieve capacity similar to high-resolution ADCs in low and moderate signal-to-noise ratio (SNR) scenarios over narrowband wireless channels. However, their integration with discrete Fourier transform based orthogonal frequency-division multiple access (OFDMA) systems is challenging due to discrete-time signal processing degradation, especially at moderate and high SNR regimes. To address this, we propose a method that integrates an analog low-pass filter (LPF) with one-bit ADCs to improve compatibility with OFDMA systems while mitigating non-linear distortion. Our approach presents an efficient solution for wideband multicarrier communication systems, optimized through simplified detection, optimal LPF bandwidth selection, and investigation of optimal detection time. The proposed scheme significantly outperforms conventional digital-domain OFDMA systems, provided that an ideal analog LPF is used. Even with a first-order LPF, it achieves comparable performance to deep learning-based systems when both use one-bit ADCs, despite its simplified structure. | Kwak, Sihoon; Min, Moonsik | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | 59388003700; 55386299100 | gsu06325@knu.ac.kr; msmin@knu.ac.kr; | IEEE WIRELESS COMMUNICATIONS LETTERS | IEEE WIREL COMMUN LE | 2162-2337 | 2162-2345 | 14 | 6 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS;COMPUTER SCIENCE, INFORMATION SYSTEMS | 2024 | 5.5 | 15.3 | 0 | 2025-05-07 | 0 | 0 | OFDM; Receivers; Wireless communication; Symbols; Baseband; Discrete Fourier transforms; Signal to noise ratio; Bandwidth; Frequency-domain analysis; Transmitters; OFDMA; one-bit ADCs; first-order LPF; cutoff frequency | MIMO SYSTEMS | cutoff frequency; first-order LPF; OFDMA; one-bit ADCs | Digital communication systems; Discrete Fourier transforms; Frequency dividing circuits; Frequency division multiple access; Image analysis; Image coding; Image quality; Image segmentation; Image texture; Image thinning; Integrated circuit design; Orthogonal frequency division multiplexing; Signal to noise ratio; Analog to digital converters; First order; First-order low-pass filter; Frequency-division multiple access; Low-pass filters; Non-linear distortions; One-bit analog-to-digital converter; Orthogonal frequency division multiple access systems; Orthogonal frequency division multiples; Orthogonal frequency-division multiple access; Cutoff frequency | English | 2025 | 2025-06 | 10.1109/lwc.2025.3552483 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Association between dementia diagnosis at dialysis initiation and mortality in older patients with end-stage kidney disease in South Korea | Background: The prevalence of dementia is 2- to 7-fold higher among patients with end-stage kidney disease (ESKD) than among the general population; however, its clinical implications in this population remain unclear. Therefore, this study aimed to determine whether comorbid dementia increases mortality among older patients with ESKD undergoing newly initiated hemodialysis. Methods: We analyzed data from the Korean Society of Geriatric Nephrology retrospective cohort, which included 2,736 older ESKD patients (>= 70 years old) who started hemodialysis between 2010 and 2017. Kaplan-Meier survival and Cox regression analyses were used to examine all-cause mortality between the patients with and without dementia in this cohort. Results: Of the 2,406 included patients, 8.3% had dementia at the initiation of dialysis; these patients were older (79.6 +/- 6.0 years) than patients without dementia (77.7 +/- 5.5 years) and included more women (male:female, 89:111). Pre-ESKD diagnosis of dementia was associated with an increased risk of overall mortality (hazard ratio, 1.503; p < 0.001), and this association remained consistent after multivariate adjustment (hazard ratio, 1.268; p = 0.009). In subgroup analysis, prevalent dementia was associated with mortality following dialysis initiation in female patients, those aged <85 years, those with no history of cerebrovascular accidents or severe behavioral disorders, those not residing in nursing facilities, and those with no or short-term hospitalization. Conclusion: A pre-ESKD diagnosis of dementia is associated with mortality following dialysis initiation in older Korean population. In older patients with ESKD, cognitive assessment at dialysis initiation is necessary. | Ye, Byung Min; Kang, Seongmin; Park, Woo Yeong; Cho, Jang-Hee; Yu, Byung Chul; Han, Miyeun; Song, Sang Heon; Ko, Gang-Jee; Yang, Jae Won; Chung, Sungjin; Hong, Yu Ah; Hyun, Young Youl; Bae, Eunjin; Sun, In O.; Kim, Hyunsuk; Hwang, Won Min; Shin, Sung Joon; Kwon, Soon Hyo; Kim, Seo Rin; Yoo, Kyung Don | Pusan Natl Univ, Sch Med, Dept Internal Med, Div Nephrol, Yangsan 50612, South Korea; Pusan Natl Univ, Yangsan Hosp, Res Inst Convergence Biomed Sci & Technol, Yangsan, South Korea; Univ Ulsan, Ulsan Univ Hosp, Coll Med, Dept Internal Med,Div Nephrol, Ulsan 44033, South Korea; Keimyung Univ, Dongsan Hosp, Sch Med, Dept Internal Med,Div Nephrol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med,Div Nephrol, Daegu, South Korea; Soonchunhyang Univ, Bucheon Hosp, Dept Internal Med, Div Nephrol, Bucheon, South Korea; Natl Med Ctr, Dept Internal Med, Div Nephrol, Seoul, South Korea; Pusan Natl Univ Hosp, Pusan Natl Univ, Sch Med, Dept Internal Med,Div Nephrol, Pusan, South Korea; Korea Univ, Guro Hosp, Coll Med, Dept Internal Med,Div Nephrol, Seoul, South Korea; Yonsei Univ, Wonju Coll Med, Dept Internal Med, Div Nephrol, Wonju, South Korea; Catholic Univ Korea, Yeouido St Marys Hosp, Coll Med, Dept Internal Med,Div Nephrol, Seoul, South Korea; Catholic Univ Korea, Daejeon St Marys Hosp, Coll Med, Dept Internal Med,Div Nephrol, Seoul, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Internal Med,Div Nephrol, Seoul, South Korea; Gyeongsang Natl Univ, Coll Med, Dept Internal Med, Jinju, South Korea; Presbyterian Med Ctr, Dept Internal Med, Div Nephrol, Jeonju, South Korea; Hallym Univ, Coll Med, Dept Internal Med, Dept Internal Med,Div Nephrol, Gyodong, Chuncheon, South Korea; Konyang Univ Hosp, Dept Internal Med, Div Nephrol, Daejeon, South Korea; Dongguk Univ, Sch Med, Ilsan Hosp, Dept Internal Med,Div Nephrol, Goyang, South Korea; Soonchunhyang Univ, Seoul Hosp, Dept Internal Med, Div Nephrol, Seoul, South Korea; Univ Ulsan, Basic Clin Translat Res Ctr, Ulsan, South Korea; Korean Soc Geriatr Nephrol, Seoul, South Korea | ; Yoo, Kyung/AAK-8096-2020 | 57193065659; 57216484878; 36344980100; 7403536291; 57203908496; 55899659500; 36162581500; 8310760600; 55038270300; 23388171000; 55125210000; 57037163300; 55880508000; 36994821600; 57194217507; 55568773500; 59710475400; 57199820603; 57198436281; 56603636300 | kim.seorin@hotmail.com; ykd9062@gmail.com; kim.seorin@pusan.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 44 | 2 | SCIE | UROLOGY & NEPHROLOGY | 2024 | 3.8 | 15.4 | 0 | 2025-05-07 | 0 | 0 | Aged; Chronic kidney failure; Dementia; Mortality; Renal dialysis | COGNITIVE IMPAIRMENT; HEMODIALYSIS-PATIENTS; ALZHEIMERS-DISEASE; RISK; CLASSIFICATION; PREVALENCE; DISORDERS; COHORT | Aged; Chronic kidney failure; Dementia; Mortality; Renal dialysis | aged; all cause mortality; Article; case fatality rate; cerebrovascular accident; chronic kidney failure; cognition; cohort analysis; dementia; dialysis; end stage renal disease; female; follow up; hemodialysis; hospitalization; human; hypertension; major clinical study; male; mortality; propensity score; retrospective study; sensitivity analysis; statistical analysis; subgroup analysis; survival analysis | English | 2025 | 2025-03 | 10.23876/j.krcp.23.151 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical guidelines for the diagnosis, evaluation, and management of hypertension for Korean children and adolescents: the Korean Working Group of Pediatric Hypertension | Pediatric hypertension (HTN) is a significant, growing health concern worldwide and also in Korea. Diagnosis, evaluation, and treatment of HTN in Korean children and adolescents are uncertain due to limitations in using the current international guidelines, since the recommendations by the American Academy of Pediatrics (AAP) and European Society of Hypertension (ESH) guidelines differ. Furthermore, these are guidelines for Western youth, who are racially and ethnically different from Koreans. In addition, reference blood pressure values for all pediatric age groups, which are essential for the diagnosis of HTN according to these two guidelines, are absent in Korea. Therefore, HTN guidelines for Korean children and adolescents should be established. The Korean Working Group of Pediatric Hypertension established clinical guidelines for the diagnosis, evaluation, and management of HTN in Korean children and adolescents. These guidelines were based on reported clinical evidence, expert recommendations, and AAP and ESH guidelines. The characteristics of Korean youth and the Korean medical and insurance system were considered during the establishment of the guidelines. By providing recommendations suitable for Korean youth, these guidelines will help in the prevention and management of childhood HTN, thus relieving the burden of cardiovascular disease in adulthood in Korea. | Park, Se Jin; An, Hyo Soon; Kim, Sung Hye; Kim, Seong Heon; Cho, Hee Yeon; Kim, Jae Hyun; Cho, Anna; Kwak, Ji Hee; Shin, Jae I. L.; Lee, Keum Hwa; Oh, Jin-Hee; Lee, Jung Won; Kim, Hae Soon; Shin, Hye-Jung; Han, Mi Young; Hyun, Myung Chul; Ha, Tae Sun; Song, Young Hwan | Hanyang Univ, Dept Internal Med, Coll Med, Coll Med, 222-1 Wangsimni Ro, Seoul 04763, South Korea; SMG SNU Boramae Med Ctr, Dept Pediat, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Pediat, Seongnam, South Korea; Seoul Natl Univ, Coll Med, Dept Pediat, Childrens Hosp, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Pediat, Bundang Hosp, Seongnam, South Korea; Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Pediat, Seoul, South Korea; Yonsei Univ, Coll Med, Severance Childrens Hosp, Dept Pediat, Seoul, South Korea; Catholic Univ Korea, St Vincents Hosp, Dept Pediat, Suwon, South Korea; Ewha Womans Univ, Seoul Hosp, Seoul Hosp, Seoul, South Korea; Natl Med Ctr, Dept Pediat, Seoul, South Korea; Kyung Hee Univ, Coll Med, Dept Pediat, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Coll Med, Dept Pediat, Cheongju, South Korea | AN, HYO SOON/HMO-5473-2023; Oh, Jin-Hee/GLS-3056-2022; Park, Se Jin/AFQ-7554-2022; SHIN, JAE IL/J-6922-2017; An, Hyo Soon/HMO-5473-2023 | 55212937600; 36089597200; 57190405339; 57213778393; 15724272900; 56553981800; 56655964000; 56041753900; 57964880100; 57193231590; 36461484000; 59831697200; 55663596500; 35173615600; 55460352800; 8704315000; 7203014522; 57188763731 | yhsong@snubh.org; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 44 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2024 | 3.8 | 15.4 | 0 | 2025-05-07 | 0 | 0 | Adolescent; Blood pressure; Child; Guideline; Hypertension | AMBULATORY BLOOD-PRESSURE; INTIMA-MEDIA THICKNESS; LEFT-VENTRICULAR HYPERTROPHY; CAROTID-ARTERY INTIMA; PULSE-WAVE VELOCITY; CHRONIC KIDNEY-DISEASE; SUSPECTED RENOVASCULAR HYPERTENSION; MASKED HYPERTENSION; DOUBLE-BLIND; RISK-FACTORS | Adolescent; Blood pressure; Child; Guideline; Hypertension | american academy of pediatrics; aortic coarctation; Article; blood pressure; blood pressure monitoring; cardiovascular disease; chronic kidney failure; clinical practice guideline; diastolic blood pressure; european society of hypertension; groups by age; human; hypertension; hypotension; Korea; Korean (people); lifestyle modification; masked hypertension; morbidity; mortality; practice guideline; proteinuria; systolic blood pressure; white coat hypertension | English | 2025 | 2025-01 | 10.23876/j.krcp.24.096 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Disaster emergency meal plans for Korean patients who require hemodialysis | Proactive planning and preparation are critical to the safety of patients on dialysis during emergencies, such as natural disasters, and pandemics, such as coronavirus disease 2019. Patients with end-stage kidney disease are particularly vulnerable to disruptions such as power outages, water shortages, transportation issues, and dialysis center closures because they can result in missed dialysis sessions and severe health deterioration. This study aimed to develop tailored dietary guidelines for Korean patients on hemodialysis by applying the U.S. Centers for Disease Control and Prevention guidelines and considering the dietary limitations of these patients. The proposed guidelines impose strict potassium, phosphorus, sodium, and fluid restrictions and include two 3-day emergency meal plans: one for scenarios involving disruptions of electricity and water supply and another for situations in which these utilities are available. The use of a food exchange list enhances the dietary flexibility of these patients. Although these guidelines cannot replace dialysis, they could mitigate the impact of emergencies on patient health by providing essential support during critical periods. | Jang, Yumi; Kim, Seong Geun; Lee, Sua; Oh, Hyun Ho; Shin, Nara; Lee, Young-Ki; Yoo, Kyung Don | Kyungpook Natl Univ, Coll Human Ecol, Dept Food Sci & Nutr, Ulsan 702701, South Korea; Univ Ulsan, Basic Clin Convergence Res Inst, Ulsan, South Korea; Inje Univ, Dept Internal Med, Sanggye Paik Hosp, Div Nephrol, Seoul, South Korea; Eulji Univ, Daejeon Eulji Med Ctr, Dept Internal Med, Div Nephrol,Sch Med, Daejeon, South Korea; Sanggye Pure Internal Med Clin, Seoul, South Korea; S&J Seoul Clin, Seoul, South Korea; Kangnam Sacred Heart Hosp, Dept Internal Med, Seoul, South Korea; Hallym Univ, Coll Med, Hallym Kidney Res Inst, Seoul, South Korea; Univ Ulsan, Ulsan Univ Hosp, Coll Med, Dept Internal Med, Ulsan, South Korea; Ulsan Univ Hosp, Univ Ulsan, Dept Internal Med, Div Nephrol,Coll Med, 25 Daehakbyeongwon Ro, Ulsan 44033, South Korea | ; Yoo, Kyung/AAK-8096-2020 | km2071@hallym.or.kr; ykd9062@gmail.com; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 44 | 2 | SCIE | UROLOGY & NEPHROLOGY | 2024 | 3.8 | 15.4 | 0 | Chronic kidney failure; Diet therapy; Disaster planning; Emergencies; Renal dialysis | NATURAL DISASTERS; DIALYSIS; PHOSPHATE; NUTRITION; MORTALITY; BALANCE; SODIUM; CARE | English | 2025 | 2025-03 | 10.23876/j.krcp.24.242 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Flood prediction in urban areas based on machine learning considering the statistical characteristics of rainfall | Urbanization has increased impervious surfaces, while climate change has intensified rainfall, leading to more frequent urban flooding. Traditional numerical models for flood prediction are accurate but time-consuming due to extensive parameter calibration and data processing. This study addresses these limitations by proposing a machine learning-based flood prediction method using a Random Forest model. By utilizing past rainfall data, 1D drainage system simulations, and 2D flood analyses, we trained the model to predict flood patterns for various rainfall events. To enhance prediction accuracy, statistical characteristics of rainfall, such as temporal distribution, were incorporated into the model. Performance metrics (RMSE, R2, MAE) for the test dataset showed values of 3.1573, 0.9682, and 0.9484 for the total rainfall model, and 2.7354, 0.9761, and 0.8942 for the model with statistical characteristics. Both models displayed high predictive accuracy relative to the numerical model, with the Random Forest model using statistical characteristics showing slightly improved performance. This method provides faster, reliable flood predictions, offering a valuable tool for real-time urban flood management and decision-making during emergency situations. | Jang, Se-Dong; Yoo, Jae-Hwan; Lee, Yeon-Su; Kim, Byunghyun | Kyungpook Natl Univ, Dept Civil Engn, Daegu 41566, South Korea | 59725289800; 59531876700; 59221437100; 56097886500 | bhkimc@knu.ac.kr; | PROGRESS IN DISASTER SCIENCE | PROG DISASTER SCI | 2590-0617 | 26 | ESCI | ENVIRONMENTAL SCIENCES;ENVIRONMENTAL STUDIES;GEOSCIENCES, MULTIDISCIPLINARY;METEOROLOGY & ATMOSPHERIC SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2024 | 3.8 | 15.4 | 0 | 2025-05-07 | 0 | 0 | Urban flood; Flood forecasting; Machine learning; Random forest; Statistical characteristic of rainfall | MODEL | Flood forecasting; Machine learning; Random forest; Statistical characteristic of rainfall; Urban flood | data set; flood control; machine learning; prediction; rainfall; urban area | English | 2025 | 2025-04 | 10.1016/j.pdisas.2025.100415 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Long-term outcomes and associated prognostic risk factors of childhood-onset lupus nephritis | Background: This study investigated the clinical characteristics and kidney outcomes of childhood-onset lupus nephritis (LN), and risk factors associated with prognosis. Methods: We enrolled 216 patients with histologically diagnosed LN during childhood. The Korean Society of Pediatric Nephrology organized a retrospective cohort study of childhood-onset LN in 13 major pediatric nephrology centers in South Korea. Results: The mean age at kidney biopsy was 13.2 +/- 3.22 years. The main forms of presentation were nephrotic syndrome and/or hematuria in 152 patients (70.4%), and the most common histological finding was World Health Organization (WHO) class IV in 138 patients (63.9%), followed by WHO class III in 34 patients (15.7%). In the outcome analysis, the mean follow-up period of the patients was 7.8 +/- 5.11 years. At last follow-up, 32 patients (14.8%) developed advanced chronic kidney disease (CKD). Male sex and failure to achieve remission at 12 months of treatment were significant risk factors for developing advanced CKD (hazard ratio of 2.57 and 2.29, respectively). Conclusion: Our study demonstrated the clinical characteristics and long-term outcomes of patients with childhood-onset LN. Male sex and failure to achieve remission in the first year of treatment were predictive of advanced CKD. Therefore, prompt awareness and close monitoring of these high-risk patients are needed, which may further improve the prognosis of children with LN. | Park, Eujin; Jung, Jiwon; Min, Jeesu; Lee, Hyeonju; Park, Min Ji; Song, Ji Yeon; Kim, Ji Hyun; Jang, Kyung Mi; Yang, Eun Mi; Ahn, Yo Han; Cho, Min Hyun; Lee, Joo Hoon; Park, Young Seo; Kim, Soon Chul; Park, Se Jin; Lee, Jung Won; Kim, Kee Hyuck; Pai, Ki Soo; Kang, Hee Gyung; Kim, Seong Heon | Hallym Univ, Dept Pediat, Kangnam Sacred Heart Hosp, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Coll Med, Coll Med,Childrens Hosp, Seoul, South Korea; Seoul Natl Univ, Dept Pediat, Childrens Hosp, 101 Daehak Ro, Seoul 03080, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Pusan Natl Univ, Childrens Hosp, Dept Pediat, Yangsan, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Pediat, Seongnam, South Korea; Yeungnam Univ, Yeungnam Univ Hosp, Dept Ophthalmol, Coll Med, Daegu, South Korea; Chonnam Natl Univ, Chonnam Natl Univ Hosp, Med Sch, Dept Pediat, Gwangju, South Korea; Seoul Natl Univ, Coll Med, Kidney Res Inst, Med Res Ctr, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Pediat, Seoul, South Korea; Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Med Sch, Jeonju, South Korea; Eulji Univ, Daejeon Eulji Med Ctr, Dept Orthoped Surg, Sch Med,Sch Med, Daejeon, South Korea; Ewha Womans Univ, Seoul Hosp, Dept Pathol, Seoul, South Korea; Natl Hlth Insurance Serv Ilsan Hosp, Dept Pediat, Goyang, South Korea; Ajou Univ, Sch Med, Dept Pediat, Suwon, South Korea | ; Park, Se Jin/AFQ-7554-2022 | 56194662500; 56518750800; 57218578053; 58663001700; 57425372600; 57204058871; 58607599100; 57203762745; 56665095200; 57223014639; 7401727726; 37112404100; 56701214400; 36087407700; 55212937600; 59831697200; 7409325956; 17137435400; 7404071546; 57213778393 | kimsh22@snu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 44 | 2 | SCIE | UROLOGY & NEPHROLOGY | 2024 | 3.8 | 15.4 | 9.19 | 2025-05-07 | 2 | 2 | Chronic renal insufficiency; Lupus nephritis; Pediatrics; Prognosis | ERYTHEMATOSUS; MALES | Chronic renal insufficiency; Lupus nephritis; Pediatrics; Prognosis | complement component C3; complement component C4; adult; Article; chronic kidney failure; cohort analysis; female; glomerulus filtration rate; hematuria; histology; histopathology; human; kidney biopsy; lupus erythematosus nephritis; major clinical study; male; nephelometry; nephrotic syndrome; prognostic assessment; qualitative analysis; retrospective study; risk factor; treatment outcome; World Health Organization | English | 2025 | 2025-03 | 10.23876/j.krcp.23.032 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Longitudinal progression trajectory of estimated glomerular filtration rate in children with chronic kidney disease: results from the KNOW-Ped CKD (KoreaN cohort study for Outcomes in patients With Pediatric Chronic Kidney Disease) | Background: The natural course of chronic kidney disease (CKD) progression in children varies according to their underlying conditions. This study aims to identify different patterns of subsequent decline in kidney function and investigate factors associated with different patterns of estimated glomerular filtration rate (eGFR) trajectories. Methods: We analyzed data from the KNOW-Ped CKD (KoreaN cohort study for Outcomes in patients With Pediatric Chronic Kidney Disease), which is a longitudinal, prospective cohort study. A latent class linear mixed model was applied to identify the trajectory Results: In a total of 287 patients, the median baseline eGFR (mL/min/1.73 m2) was 63.3, and the median age was 11.5 years. The eGFR decline rate was -1.54 during a 6.0-year follow-up. The eGFR trajectory over time was classified into four groups. Classes 1 (n = 103) and 2 (n = 11) had a slightly reduced eGFR at enrollment with a stable trend (Delta eGFR, -0.2/year) and a rapid decline eGFR over time (Delta eGFR, -10.5/year), respectively. Class 3 had a normal eGFR (n = 16), and class 4 had a moderately reduced eGFR (n = 157); both these chasses showed a linear decline in eGFR over time (Delta eGFR, -4.1 and -2.4/year). In comparison with classes 1 and 2, after adjusting for age, causes of primary renal disease, and baseline eGFR, nephrotic-range proteinuria was associated with a rapid decline in eGFR (odds ratio, 8.13). Conclusion: We identified four clinically relevant subgroups of kidney function trajectories in children with CKD. Most children showed a linear decline in eGFR; however, there are different patterns of eGFR trajectories. | Yang, Eun Mi; Kim, Jayoun; Park, Eujin; Han, Kyoung Hee; Kim, Seong Heon; Cho, Heeyeon; Il Shin, Jae; Cho, Min Hyun; Lee, Joo Hoon; Kim, Ji Hyun; Kang, Hee Gyung; Ha, Il-Soo; Ahn, Yo Han | Chonnam Natl Univ, Chonnam Natl Univ Hosp, Med Sch, Dept Pediat, Gwangju, South Korea; Seoul Natl Univ Hosp, Med Res Collaborating Ctr, Seoul, South Korea; Korea Univ, Guro Hosp, Dept Pediat, Seoul, South Korea; Jeju Natl Univ, Coll Med, Dept Pediat, Jeju, South Korea; Seoul Natl Univ, Childrens Hosp, Dept Pediat, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Pediat, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul, South Korea; Yonsei Univ, Coll Med, Dept Pediat, Seoul, South Korea; Severance Childrens Hosp, Div Pediat Nephrol, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Univ Ulsan, Asan Med Ctr Childrens Hosp, Coll Med, Dept Pediat, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Pediat, Seongnam, South Korea; Seoul Natl Univ, Coll Med, Kidney Res Inst, Med Res Ctr, Seoul, South Korea; Seoul Natl Univ, Wide River Inst Immunol, Hongcheon, South Korea | SHIN, JAE IL/J-6922-2017 | 56665095200; 56272817800; 56194662500; 58389645900; 57213778393; 15724272900; 59594649700; 7401727726; 37112404100; 58607599100; 7404071546; 57226423279; 57223014639 | yhahn@snu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 44 | 2 | SCIE | UROLOGY & NEPHROLOGY | 2024 | 3.8 | 15.4 | 4.59 | 2025-05-07 | 1 | 1 | Child; Chronic kidney disease; Disease progression; Latent class linear mixed model; Trajectory | RISK-FACTORS; GFR; STAGE; ADOLESCENTS; GUIDELINE; FAILURE; SEX | Child; Chronic kidney disease; Disease progression; Latent class linear mixed model; Trajectory | albumin; cholesterol; hemoglobin; phosphorus; potassium; uric acid; acidosis; Article; body mass; child; chronic kidney failure; cohort analysis; controlled study; diagnostic test accuracy study; disease exacerbation; dyslipidemia; entropy; estimated glomerular filtration rate; gestational age; glomerulopathy; human; hyperuricemia; kidney disease; kidney function; longitudinal study; major clinical study; male; prematurity; proteinuria; renin angiotensin aldosterone system; treatment outcome | English | 2025 | 2025-03 | 10.23876/j.krcp.23.198 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Pre-Phased 1-bit Reflective Passive Metasurface With Optimum Number of Pre-Phasing for Low QLL and SLL at 140 GHz | Recent advancements introduced a pre-phased reflective metasurface (MS) using 1-bit control to suppress the quantization lobe (QL) inherent in a typical 1-bit MS under plane wave incidence, particularly in millimeter and submillimeter wave bands. However, the optimal method for pre-phasing using random phases has yet to be fully explored. This study investigates the optimal number of pre-phasing, which denotes the minimum number of discrete random phases for effective suppression of QLs and side lobes while ensuring low design complexity. The results indicate that employing four discrete phases, equally spaced at 45(degrees) intervals, is the optimal solution for both normal and oblique incidences. The random phases with a 45(degrees) separation are implemented into four pairs of unit cells with passive ON/OFF switching using multilayer PCBs at 140 GHz. Each unit cell consisted of a metallic patch coupled to a transmission (Tx) line through a slot, with embedded static ON/OFF switching in the Tx line to enable 1-bit reflection phase control. Finally, three MSs with 30 x 30 unit cells, each with fixed random pre-phases, are designed and fabricated to reflect normal incidence at reflection angles (theta(r)) of 15(degrees), 30(degrees), and 45(degrees) at 140 GHz. The experiment results demonstrate peak reflected beams at 15(degrees), 29(degrees), and 45(degrees) with frequencies of 139.7, 139.1, and 135.9 GHz, respectively. In addition, significant reductions in QL to -20 dB were observed, along with a reflection efficiency of 26%, and a 3 dB gain bandwidth exceeding 10%, on average, across all reflection angles in the 140 GHz band. | Kim, Taeyoung; Lee, Sangmin; Oh, Seongwoog; Kim, Jinhyun; Oh, Jungsuek; Choi, Sangjo | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kwangwoon Univ, Dept Elect Convergence Engn, Seoul 01897, South Korea; Seoul Natl Univ, Inst New Media & Commun, Dept Elect & Comp Engn, Seoul 08826, South Korea | 59471405700; 57213176293; 57198898964; 59089657500; 35194285700; 36697690200 | kty6546@knu.ac.kr; sangmin2@knu.ac.kr; ohseongwoog@kw.ac.kr; jinhyun111@snu.ac.kr; jungsuek@snu.ac.kr; sangjoc@knu.ac.kr; | IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION | IEEE T ANTENN PROPAG | 0018-926X | 1558-2221 | 73 | 2 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2024 | 5.8 | 15.4 | 0 | 2025-05-07 | 0 | 0 | Reflection; Switches; Structural beams; Reconfigurable intelligent surfaces; Quantization (signal); Metasurfaces; Antennas and propagation; 6G mobile communication; Finite element analysis; Control systems; Pre-phased 1-bit metasurface (MS); quantization lobe (QL); reconfigurable intelligent surface (RIS); reflective metasurface | ELECTRONICALLY RECONFIGURABLE REFLECTARRAY | Pre-phased 1-bit metasurface (MS); quantization lobe (QL); reconfigurable intelligent surface (RIS); reflective metasurface | Reflection; Submillimeter waves; Metasurface; Pre-phased 1-bit metasurface; Quantisation; Quantization lobe; Random-phase; Reconfigurable; Reconfigurable intelligent surface; Reflective metasurface; Unit cells; Millimeter waves | English | 2025 | 2025-02 | 10.1109/tap.2024.3510861 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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