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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article 3-Deoxysappanchalcone Inhibited High Mobility Group Box Protein 1-Mediated Severe Inflammatory Responses Background/Objectives: Phytochemicals are increasingly recognized for their therapeutic potential in treating various diseases, including vascular disorders. High mobility group box 1 (HMGB1), a key mediator of late-stage sepsis, triggers the release of proinflammatory cytokines, leading to inflammation and systemic complications. Elevated plasma levels of HMGB1 impair diagnosis and prognosis while worsening outcomes in inflammatory conditions. 3-deoxysappanchalcone (3-DSC), a compound derived from Biancaea sappan (L.) Tod., has demonstrated anti-influenza and anti-allergic effects, though its role in HMGB1-mediated severe vascular inflammation remains unclear. This study hypothesized that 3-DSC could modulate lipopolysaccharide-induced HMGB1 activity and its downstream inflammatory pathways in human umbilical vein endothelial cells (HUVECs). Methods: In vitro and in vivo permeability; cell viability, adhesion, and excavation of leukocytes; the development of cell adhesion molecules; and lastly, the production of proinflammatory substances were investigated on human endothelial cells and mouse disease models to investigate the efficacy of 3-DSC in inflammatory conditions. Results: Experiments revealed that 3-DSC inhibited HMGB1 translocation from HUVECs, reduced neutrophil adhesion and extravasation, suppressed HMGB1 receptor formation, and blocked nuclear factor-kappa B (NF-kappa B) activation and tumor necrosis factor-alpha (TNF-alpha) synthesis. Conclusions: These findings suggest that 3-DSC effectively mitigates HMGB1-driven inflammation, offering promise as a therapeutic candidate for inflammatory diseases. Lee, Jinhee; Han, Gyuri; Bae, Jong-Sup Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Coll Pharm, CMRI, Daegu 41566, South Korea 59150416200; 59912983300; 16021543200 aadd8563@gmail.com; f11074@naver.com; baejs@knu.ac.kr; PHARMACEUTICALS PHARMACEUTICALS-BASE 1424-8247 18 5 SCIE CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY 2024 4.8 14.3 N/A 1 1 3-deoxysappanchalcone; barrier integrity; LPS; HMGB1; endothelium NF-KAPPA-B; CAESALPINIA-SAPPAN; ANTIOXIDANT ACTIVITY; HMGB1; ACTIVATION; OXIDATION; RELEASE 3-deoxysappanchalcone; barrier integrity; endothelium; HMGB1; LPS 3 deoxysappanchalcone; catalase; cell adhesion molecule; chalcone; endothelial leukocyte adhesion molecule 1; glutathione peroxidase; high mobility group B1 protein; immunoglobulin enhancer binding protein; intercellular adhesion molecule 1; lipopolysaccharide; malonaldehyde; reactive oxygen metabolite; superoxide dismutase; toll like receptor 2; toll like receptor 4; tumor necrosis factor; unclassified drug; vascular cell adhesion molecule 1; animal cell; animal experiment; animal model; antioxidant activity; Article; cell adhesion; cell viability; controlled study; enzyme activity; enzyme linked immunosorbent assay; human; human cell; inflammation; male; mouse; MTT assay; NF kB signaling; nonhuman; protein expression level; real time polymerase chain reaction; transendothelial and transepithelial migration; transwell assay; umbilical vein endothelial cell English 2025 2025-05-16 10.3390/ph18050731 바로가기 바로가기 바로가기 바로가기
Article Carbon-based catalysts in advanced oxidation processes for sulfonamide degradation: Environmental challenges and innovations The widespread presence of sulfonamide (SFA) antibiotics in the environment, due to their extensive use in medicine, poses significant ecological and health risks, including bioaccumulation and the promotion of antibiotic resistance. Various techniques for removing SFA antibiotics from water and wastewater have been investigated, encompassing biological, physical, and chemical methods. Advanced oxidation processes (AOPs), noted for their rapid reaction rates and potent oxidation capabilities, have been increasingly recognized as effective for degrading SFA in aquatic environments. In this review paper, the potential of carbocatalytic remediation is highlighted, showcasing an innovative approach that utilizes carbon-based catalysts for the degradation of SFA. In AOPs, the role of a carbocatalyst is crucial for the formation of reactive oxygen species (ROS) and electron transfer, which contribute to the efficient breakdown of SFA. The study further identifies and delineates multiple research gaps, proposing them as key areas for future investigational directions. Al Masud, Md Abdullah; Samaraweera, Hasara Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, Daegu 41566, South Korea; Western Univ, Dept Civil & Environm Engn, London, ON N6H 0B6, Canada Masud, Md Abdullah Al/JEF-1055-2023; Samaraweera, Hasara/ABE-8597-2021 57542255300; 57219393313 mmasud1@ua.edu; CURRENT OPINION IN ENVIRONMENTAL SCIENCE & HEALTH CURR OPIN ENV SCI HL 2468-5844 46 ESCI ENVIRONMENTAL SCIENCES 2024 6.6 14.3 0 2025-06-11 0 0 English 2025 2025-08 10.1016/j.coesh.2025.100628 바로가기 바로가기 바로가기 바로가기
Article Chitinase 3-like protein 1 deficiency ameliorates drug-induced acute liver injury by inhibition of neutrophil recruitment through lipocalin-2 Chitinase-3-like protein 1 (Chi3l1) is a member of the mammalian Chitinase-like protein family, and several studies reported that Chi3l1 is associated with various inflammatory diseases as well as liver diseases. Acetaminophen (APAP) is usually used for antipyretic drug, but its overdose induces acute liver injury (ALI). Several studies reported that subsequent inflammatory responses of the immune system play a critical role in the severity and outcome of APAP-induced ALI. In the present study, we investigated the role of Chi3l1 and its mechanism during APAP-induced ALI using Chi3l1 knock-out (KO) mice. We explored the function of Chi3l1 using APAP-injected KO mice and sought proteins associated with Chi3l1 through biological research data program for investigating mechanism. Liver histological analysis revealed that APAP-induced ALI was attenuated in KO mice compared to wild-type (WT) mice. We observed that APAP-induced neutrophil infiltration was decreased in the liver of KO mice compared to WT mice. To investigate this mechanism, we sought proteins potentially associated with Chi3l1 by mRNA sequencing and protein correlation analysis data. We found lipocalin-2 (Lcn2) and examined Chi3l1, Lcn2, and their relationship in the APAP-induced ALI model using recombinant proteins and antibodies. Our results suggest that Chi3l1 deficiency ameliorates APAP-induced liver injury through abrogating Lcn2-mediated neutrophil infiltration in the liver. Kim, Ji Hye; Yeo, In Jun; Son, Dong Ju; Han, Sang Bae; Yoon, Do Young; Lee, Dong Hun; Hong, Jin Tae Chonnam Natl Univ, Res Ctr Ecomimet, Dept Biol Sci, Gwangju, South Korea; Chungbuk Natl Univ, Coll Pharm, Cheongju, Chungbuk, South Korea; Chungbuk Natl Univ, Med Res Ctr, Cheongju, Chungbuk, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu, South Korea; Konkuk Univ, Dept Biosci & Biotechnol, Seoul, South Korea 57191681866; 57201941942; 7101868468; 57216616464; 35084588800; 58914633800; 59661025500 dhun@jnu.ac.kr; jinthong@chungbuk.ac.kr; FRONTIERS IN PHARMACOLOGY FRONT PHARMACOL 1663-9812 16 SCIE PHARMACOLOGY & PHARMACY 2024 4.8 14.3 0 2025-05-07 0 0 acetaminophen; LCN2; leukocyte recruitment; oxidative stress ALCOHOLIC LIVER; ACETAMINOPHEN; INFLAMMATION; YKL-40; DAMAGE; CELLS; HEPATOTOXICITY; IDENTIFICATION; INFILTRATION; MACROPHAGES acetaminophen; CHI3L1; LCN2; leukocyte recruitment; oxidative stress alanine aminotransferase; anti Lcn2; antibody; aspartate aminotransferase; chitinase 3 like protein 1; hydrogen peroxide; malonaldehyde; myeloperoxidase; neutrophil gelatinase associated lipocalin; paracetamol; pentobarbital; unclassified drug; acute drug induced hepatitis; animal cell; animal experiment; animal model; animal tissue; Article; chitinase 3 like protein 1 deficiency; chronic liver disease; female; flow cytometry; fluorescence activated cell sorting; histology; histopathology; immunohistochemistry; inflammation; Kupffer cell; leukocyte; liver cell; liver disease; liver toxicity; male; mouse; mRNA expression level; neutrophil; neutrophil chemotaxis; nonhuman; oxidative stress; protein deficiency; Western blotting English 2025 2025-03-24 10.3389/fphar.2025.1548832 바로가기 바로가기 바로가기 바로가기
Article Effect of Tegoprazan on Tacrolimus and Mycophenolate Levels in Kidney Transplant Recipients: A Randomized Controlled Study Using a Smart Trial Platform Background/Objectives: Potassium-competitive acid blockers (P-CABs) offer rapid gastric acid inhibition and lower toxicity compared to proton pump inhibitors (PPIs). This study investigates the drug-drug interaction between P-CABs and immunosuppressants tacrolimus and mycophenolate in kidney transplant recipients (KTRs). Methods: Sixty-two KTRs were randomized to receive either 50 mg of tegoprazan or 20 mg of pantoprazole. Patients were monitored using a smart clinical trial platform incorporating remote monitoring and safety management systems, which tracked drug adherence and vital signs. General and gastrointestinal (GI) symptoms were surveyed via a self-developed app on patients' phones. Trough levels of tacrolimus and mycophenolate were measured every 4 weeks over 12 weeks. Results: Medication adherence was 100% in both groups. A total of 13,726 biometric data points and 5031 questionnaire responses were collected, with 5704 feedback messages and 56 video visits conducted. At 12 weeks, the mean trough levels of tacrolimus and mycophenolate were similar between the tegoprazan and pantoprazole groups (5.5 +/- 1.6 vs. 5.8 +/- 2.0 ng/mL, p = 0.50 and 2.7 +/- 1.4 vs. 2.6 +/- 1.4 mu g/mL, p = 0.57, respectively). The intragroup difference in trough levels from baseline to week 12 was not significant in either group. GI symptoms scores, vital signs, and allograft function remained stable and comparable between groups. Conclusions: Tegoprazan does not alter the blood trough levels of tacrolimus and mycophenolate during the 12-week follow-up in KTRs and has a similar impact on GI symptoms as pantoprazole. This study confirms the feasibility and safety of using a smart clinical trial system with remote monitoring for randomized trials. Lee, Seong-Wook; Jeon, You Hyun; Lim, Jeong-Hoon; Seo, Jung Ju; Jung, Hee-Yeon; Choi, Ji-Young; Park, Sun-Hee; Kim, Chan-Duck; Kim, Yong-Lim; Cho, Jang-Hee Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Nephrol,Dept Internal Med, Daegu 41944, South Korea Lim, Jeong-Hoon/ABE-6003-2020 58844486200; 57820096000; 55360244300; 56010297100; 57196396467; 7501393222; 7501831741; 8558530700; 59962823400; 7403536291 maybee0914@gmail.com; yh-jeon@knu.ac.kr; jh-lim@knu.ac.kr; bravo2510@hanmail.net; hy-jung@knu.ac.kr; jyss1002@hanmail.net; sh-park@knu.ac.kr; drcdkim@knu.ac.kr; ylkim@knu.ac.kr; jh-cho@knu.ac.kr; PHARMACEUTICALS PHARMACEUTICALS-BASE 1424-8247 18 6 SCIE CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY 2024 4.8 14.3 0 0 drug interactions; information and communication technology; kidney transplant; mycophenolate; potassium-competitive acid blocker; tacrolimus; tegoprazan PROTON PUMP INHIBITORS; BLOOD-CONCENTRATION; CYCLOSPORINE-A; PHARMACOKINETICS; PANTOPRAZOLE; RABEPRAZOLE; EXPOSURE; CYP3A5 drug interactions; information and communication technology; kidney transplant; mycophenolate; potassium-competitive acid blocker; tacrolimus; tegoprazan English 2025 2025-06-01 10.3390/ph18060830 바로가기 바로가기 바로가기 바로가기
Article Effects of Acquisition Time and Viral Load of Source Plants on Infections of Two Tomato Begomoviruses in Bemisia tabaci Tomato yellow leaf curl disease poses one of the most severe threats to tomato production worldwide. This disease is associated with a group of closely related tomato yellow leaf curl viruses. These viruses can be transmitted by the sweet potato whitefly (Bemisia tabaci) in a persistent-circulative mode. Virus particles can infect the midgut and filter chamber of whiteflies feeding on infected plants, circulate in the hemolymph, and eventually infect the primary salivary gland (PSG) of whiteflies. Later, the whiteflies feed on healthy plants, and viral particles are introduced into the plants through their saliva. Virus-vector interactions play a crucial role in the efficiency and dynamics of virus transmission. In this study, we assessed the effects of the acquisition time and viral load of source plants on infections of two tomato begomoviruses, tomato yellow leaf curl Thailand virus (TYLCTHV) and tomato leaf curl Taiwan virus (ToLCTV), in B. tabaci Middle East-Asia Minor 1. We found that more viruses were acquired and accumulated in the whitefly midgut and PSG before reaching a plateau when the acquisition time increased and when the source plant had a higher viral load. The midgut and PSG acquired and accumulated more TYLCTHV than ToLCTV with the same acquisition time and regardless of the viral loads in coinfected source plants. These results not only help us to understand virus-vector interactions but also help in developing integrated disease management strategies. Huang, Ya-Yu; Li, Wei-Hua; Lee, Kyeong-Yeoll; Tsai, Wen-Shi; Tsai, Chi-Wei Natl Taiwan Univ, Dept Entomol, Taipei 106, Taiwan; Kyungpook Natl Univ, Dept Plant Med, Daegu 41566, South Korea; Natl Chiayi Univ, Dept Plant Med, Chiayi 600, Taiwan Tsai, Chi-wei/AAP-9609-2020 59940784300; 57222360165; 57217153096; 16043579800; 8703710100 r11632009@ntu.edu.tw; f06632007@ntu.edu.tw; leeky@knu.ac.kr; wenshi.tw@mail.ncyu.edu.tw; chiwei@ntu.edu.tw; AGRICULTURE-BASEL AGRICULTURE-BASEL 2077-0472 15 11 SCIE AGRONOMY 2024 3.6 14.3 N/A 0 0 Begomovirus; coinfection; Geminiviridae; virus-vector interaction; whitefly LEAF-CURL-VIRUS; SARDINIA-VIRUS; TRANSMISSION; VECTOR; EMERGENCE; DNA; PCR Begomovirus; coinfection; Geminiviridae; virus–vector interaction; whitefly Anatolia; Middle East; Turkey; disease spread; disease transmission; disease vector; infectious disease; leaf area; saliva; viral disease; virus English 2025 2025-05-30 10.3390/agriculture15111195 바로가기 바로가기 바로가기 바로가기
Article Inhibition of GSK-3β Restores Differentiation Potential of Late-Passage Mesenchymal Stem Cells Background/Objectives: Mesenchymal stem cells (MSCs) are regarded as a promising cell type with significant therapeutic benefits owing to their ease of isolation, maintenance, and characterisation. However, repeated passages during cultural maintenance frequently result in cellular senescence, limiting their utility in regenerative medicine. Methods: We investigated the differentiation capability between early- (P3) and late-passage MSCs (>P15) and tested the potential of Wnt agonist 99021 to reverse MSCs using standard cell culture protocols that define minimal criteria for MSCs, primarily tri-lineage differentiation assays, biochemical staining gene expression analysis, and senescence assays. Results: We initially noticed distinct signs of morphological aging between early- (P3) and late-passage MSCs (>P15) and further examined the differentiation capability between early- (P3) and late-passage MSCs (>P15). We found a diminished differentiation potential in late-passage MSCs. Our senescence assay also revealed >P15 cells were able to absorb the senescence dye, indicating that >P15 MSCs underwent senescence. We further demonstrated that CHIR 99021 reversed the differentiation inhibitory potential-mediated impasse of late-passage MSCs by employing tri-lineage specific differentiation assays, biochemical labelling, and gene expression analysis. Senescence assays after CHIR 99021 treatment also revealed no senescence dye uptake at all. Conclusions: Our findings demonstrated that CHIR 99021 Wnt agonist maybe aids in the reversal of MSC aging-related differentiation inhibition glitches and offers a proven demonstrated protocol for rejuvenating late-passage MSCs. Thus, CHIR99021 treatment inherently reverts the tri-lineage potency in late-passage MSCs, and this method could be further employed to ensure a plentiful MSC source for clinical purposes. Govarthanan, Kavitha; Sundaram, Raja Sundari Meenakshi; Richard, Arthi Sunil; Chabathula, Siva Chander; Rupert, Secunda; Sathyanesan, Jeswanth; Verma, Rama Shanker; Jeyaraman, Naveen; Jeyaraman, Madhan; Rajendran, Ramya Lakshmi; Gangadaran, Prakash; Ahn, Byeong-Cheol Indian Inst Technol Madras, Dept Biotechnol, Chennai 600036, Tamil Nadu, India; Inst Stem Cell Sci & Regenerat Med, Ctr Cardiovasc Biol & Dis, Bengaluru 560065, Karnataka, India; Govt Stanley Hosp, Dept Regenerat Med & Res, Chennai 600001, Tamil Nadu, India; Dr MGR Educ & Res Inst, ACS Med Coll & Hosp, Dept Orthopaed, Chennai 600077, Tamil Nadu, India; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, FOUR KNU Convergence Educ Program Biomed Sci Creat, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Nucl Med, Daegu 41944, South Korea S, Raja/HPD-7505-2023; Jeyaraman, Madhan/ABB-8464-2020; Rajendran, Ramya/AAV-6338-2021; Gangadaran, Prakash/AAV-3102-2021 56966697100; 57348025200; 57226578279; 59753861700; 59662865900; 14321631800; 7402270306; 57219306833; 57216926503; 57195318729; 54393130400; 7202791511 govarthanan_kavitha@yahoo.co.in; bt.raji@gmail.com; arthihard@gmail.com; siva.chabathula@gmail.com; drsecunda@gmail.com; dr_jeswanth@yahoo.co.in; vermars@faculty.iitm.ac.in; naveenjeyaraman@yahoo.com; madhanjeyaraman@gmail.com; ramyag@knu.ac.kr; prakashg@knu.ac.kr; abc2000@knu.ac.kr; PHARMACEUTICALS PHARMACEUTICALS-BASE 1424-8247 18 4 SCIE CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY 2024 4.8 14.3 0 2025-05-07 0 0 MSCs; senescence; rejuvenation; CHIR 99021; tri-lineage; differentiation IN-VITRO; BETA CHIR 99021; differentiation; MSCs; rejuvenation; senescence; tri-lineage CD34 antigen; collagen type 1; fatty acid binding protein 4; glycogen synthase kinase 3beta; laduviglusib; osteopontin; peroxisome proliferator activated receptor gamma; receptor type tyrosine protein phosphatase C; transcription factor RUNX2; aging; Article; biochemical labelling; cell aging; cell culture; cell differentiation; cell proliferation; cell viability; colony formation; differentiation; enzyme linked immunosorbent assay; flow cytometry; gene expression; gene ontology; human; human cell; human tissue; immunocytochemistry; immunofluorescence assay; in vitro study; induced pluripotent stem cell; karyotyping; mesenchymal stem cell; morphological analysis; mRNA expression level; phenotype; protein expression; real time polymerase chain reaction; rejuvenation; RNA extraction; RNA sequence; RNA sequencing; senescence; umbilical cord tissue; Western blotting English 2025 2025-03-28 10.3390/ph18040483 바로가기 바로가기 바로가기 바로가기
Editorial Material Organic Management Approaches and Practices to Support Sustainable Horticultural and Fruit Plants Production Win, Nay Myo; Kang, In-Kyu Natl Inst Hort & Herbal Sci, Apple Res Ctr, RDA, Daegu 43100, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea 42462548000; 59877663800 naymyowin@korea.kr; kangik@knu.ac.kr; AGRICULTURE-BASEL AGRICULTURE-BASEL 2077-0472 15 8 SCIE AGRONOMY 2024 3.6 14.3 0 2025-05-07 0 0 English 2025 2025-04-08 10.3390/agriculture15080801 바로가기 바로가기 바로가기 바로가기
Review Bright Prospects, Lingering Challenges: CsPbBr3 Quantum Dots for Environmental Sensing The quest for efficient and versatile environmental sensing technologies has led researchers to explore novel materials. The advent of CsPbBr3 perovskite quantum dots (PQDs) has revolutionized the field of optoelectronics, offering a new paradigm for sensing applications due to their exceptional optical properties. This review paper examines the opportunities and challenges associated with using CsPbBr3 PQDs for environmental sensing applications, focusing on their distinctive properties, synthesis methods, and practical implementations. We discuss the potential of CsPbBr3 PQDs in various environmental sensing applications, including pollutant detection, temperature and pH monitoring, and gas and heavy-metal ion sensing. Additionally, we highlight the challenges and limitations posed by the stability and durability of these PQDs in different environments, particularly under conditions of humidity and temperature fluctuations. Lastly, we explore future perspectives and opportunities for CsPbBr3 PQDs in environmental sensing, emphasizing the importance of addressing stability and toxicity concerns. This review provides a comprehensive overview of the current state of research on CsPbBr3 PQDs for environmental sensing applications, offering insights into potential advancements and the challenges that remain. Ogunleye, Abdulazeez M.; Adeshina, Mohammad Awwal; Kim, Gunwoo; Kim, Hyunmin; Park, Jonghoo Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 37224, South Korea; Daegu Gyeongbuk Inst Sci & Technol DGIST, Div Biotechnol, Daegu 42988, South Korea Kim, Gunwoo/AAL-1188-2021 57933554600; 57216582237; 59422417600; 57192552925; 57196408322 jonghoopark@knu.ac.kr; CRYSTAL GROWTH & DESIGN CRYST GROWTH DES 1528-7483 1528-7505 25 9 SCIE CHEMISTRY, MULTIDISCIPLINARY;CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY 2024 3.4 14.5 0 2025-05-07 0 0 LIGHT-EMITTING-DIODES; PEROVSKITE NANOCRYSTALS; FLUORESCENT SENSOR; PHOTOLUMINESCENCE; TEMPERATURE; EFFICIENT; LUMINESCENCE; LIGAND Layered semiconductors; Nanocrystals; Environmental sensing; Novel materials; Optical-; Pollutant detection; Property; Review papers; Sensing applications; Sensing technology; Synthesis method; Temperature monitoring; Perovskite English 2025 2025-04-10 10.1021/acs.cgd.4c01484 바로가기 바로가기 바로가기 바로가기
Article Deuterium-Enhanced Photoluminescence and Magnetic Properties in Octanuclear Terbium(III) Complexes Containing a Hexadentate N2O4-Type Ligand Two new octanuclear lanthanide coordination complexes [Tb8(dpim)4(mu-OH)8(NO3)8] (1) and [Tb8(dpim)4(mu-OD)8(NO3)8] (2) were prepared using terbium(III) nitrate salt in ethanol and deuterium oxide (for only 2) and a hexadentate ligand [(2,2-dimethyl-1,3-propanediyl)bis(iminomethylene)bis(6-methoxyphenol)] (H2dpim). The molecular structures of 1 and 2 comprise octanuclear compounds featuring eight Tb(III) ions, four dpim2- ligands, eight OH-/OD- bridges, and eight nitrato ligands. One Tb(III) ion is located in the inner N2O2 compartment of dpim2- and bonded to two nitrate anions. Two Tb(III) ions are located in the distorted outer O2O2 ' compartment of the dpim2- ligand and coordinated by a hydroxyl bridge. Three Tb(III) ions are connected through a hydroxyl group, while one Tb(III) ion is connected to an adjacent [Tb2(dpim)]4+ derivative unit. Consequently, the structure consists of an octanuclear complex with four corner-sharing incomplete cuboidal {Tb3O4} cores, decorated with eight terminal nitrato, methoxy, and phenolato ligands. The structure of 2 is isomorphic to that of 1, except that it contains OD-. Photoluminescence spectroscopy revealed that the octanuclear complexes exhibited strong luminescence in the 488-620 nm range. Complex 2, with OD- bridging ligands, exhibited considerably higher emission than 1 because of the deuteration effect. The quantum yields of 1 and 2 were 19 and 75%, respectively. Magnetic measurements revealed that the magnetic behavior of 2 exhibited a slightly stronger contribution from the depopulation of Stark levels and antiferromagnetic couplings compared to 1. Le, Ngoc Tram Anh; Son, Younghu; Kim, Inhoo; Tokunaga, Ryuya; Hayami, Shinya; Min, Kil Sik Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; DGIST, Dept Phys & Chem, Daegu 42988, South Korea; Kumamoto Univ, Dept Chem, Kumamoto 8608555, Japan; Kyungpook Natl Univ, Educ & Sci Educ Res Inst, Dept Chem, Daegu 41566, South Korea Hayami, Shinya/E-7019-2014; Le, Ngoc/R-1561-2019 58793817000; 57216839175; 59703223000; 57877777400; 7006400078; 59818026100 minks@knu.ac.kr; CRYSTAL GROWTH & DESIGN CRYST GROWTH DES 1528-7483 1528-7505 25 7 SCIE CHEMISTRY, MULTIDISCIPLINARY;CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY 2024 3.4 14.5 0 2025-05-07 1 1 SINGLE-MOLECULE MAGNET; NITRONYL NITROXIDE; LUMINESCENCE; TB Deuterium compounds; Indium phosphide; Lutetium compounds; Magnetometry; Nitrates; Nitric oxide; Nitrogen oxides; Photoluminescence spectroscopy; Terbium compounds; Hexadentate; Hydroxyl groups; Lanthanide coordination complexes; Methoxyphenols; Nitrate anions; Nitrate salts; Nitrato ligands; Octanuclear compounds; OH -; Property; Ligands English 2025 2025-03-21 10.1021/acs.cgd.5c00140 바로가기 바로가기 바로가기 바로가기
Article Enhanced Lithium-Ion Storage with Nitrogen-Enriched Triazine Covalent Organic Frameworks via Mechanical Exfoliation Covalent organic frameworks (COFs) often demonstrate limited electrochemical performance due to the stacking tendency of their 2D-extended structures, particularly in triazine COFs (T-COFs), where strong pi-pi interactions cause an eclipsed arrangement. This stacking effect conceals the active sites inside the 1D channels, hindering efficient ion transport, especially under high-charge/discharge conditions. The slow movement of Li+ ions through these channels results in the poor utilization of redox-active sites, thereby diminishing both capacity and rate capabilities. In this work, we introduce a facile method to improve the electrochemical properties of COFs when used as anode materials in lithium-ion batteries. A 2D-COF was synthesized by the nucleophilic substitution of cyanuric chloride with melamine, followed by mechanical exfoliation into 2D few-layer nanosheets using a simple mechanical grinding technique. These bulk and exfoliated COFs were characterized using FTIR, XPS, TGA, FESEM, and DRS. Photophysical studies indicate that both bulk and E-COFs exhibited low band gap values of 3.31 and 4.25 eV, respectively, showing their semiconducting nature. Electrochemical tests reveal that the exfoliated COF delivers a maximum capacity of 847 mAh g-1, with a Coulombic efficiency of 72% at 0.2 A g-1. The shortened Li+ diffusion pathways in exfoliated COF led to significantly enhanced redox site utilization and faster lithium storage kinetics, in contrast to the diffusion-limited behavior seen in bulk COF. Vargheese, Stella; Konavarapu, Satyanarayana K.; Kim, Giyong; Kim, Sung Yeol Karpagam Acad Higher Educ, Ctr Adv Battery Res, Coimbatore 641021, India; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehakro, Daegu 41566, South Korea 57208299950; 57191433741; 57354461700; 19337822900 sykim.knu@gmail.com; CRYSTAL GROWTH & DESIGN CRYST GROWTH DES 1528-7483 1528-7505 25 8 SCIE CHEMISTRY, MULTIDISCIPLINARY;CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY 2024 3.4 14.5 0 2025-05-07 0 0 CATHODE MATERIALS; NANOSHEETS; ELECTRODES Exfoliation (materials science); Lithium compounds; Redox reactions; Covalent organic frameworks; Eclipsed arrangement; Electrochemical performance; Extended structures; Li +; Lithium ion storages; Mechanical exfoliation; Nitrogen-enriched; Stackings; π-π interaction; Lithium-ion batteries English 2025 2025-03-28 10.1021/acs.cgd.4c01562 바로가기 바로가기 바로가기 바로가기
Article Fluorine-Doped N-Type α-Ga2O3 and Its Phase Stability In this work, we investigated the impacts of fluorine (F) doping on the electrical and structural properties of metastable alpha-Ga2O3 grown on sapphire. Compared to Sn, which is a Ga-substituting dopant and one of the more common dopants for alpha-Ga2O3, doping with F resulted in more conductive alpha-Ga2O3 with Hall mobility as high as 42 cm2/Vs and the carrier concentrations of similar to 1 x 1019 cm-3 at room temperature. In contrast, Sn-doped alpha-Ga2O3 with similar carrier concentrations exhibited a Hall mobility of less than 10 cm2/Vs. Furthermore, F-doped alpha-Ga2O3 showed greater thermal stability in both electrical and structural properties compared to undoped and Sn-doped alpha-Ga2O3. The phase stability was enhanced such that single-phase F-doped alpha-Ga2O3 could be annealed or grown at temperatures as high as 700 degrees C. A Ti-based metal contact formed on F-doped alpha-Ga2O3 exhibited an Ohmic behavior with a specific contact resistivity of 6.5 x 10-5 Omegacm2 after annealing. Overall, doping with F has shown promising results for high-performance alpha-Ga2O3 devices. Choi, Yoonho; Kim, Chanwoong; Hwang, Youngsoo; Park, Suhyun; Kang, Ha Young; Chakraborty, Surajit; Chung, Roy Byung Kyu Kyungpook Natl Univ, Adv Mat Sci & Engn Dept, Daegu 41566, South Korea; Kyungpook Natl Univ, KNU Adv Mat Res Inst, Daegu 41566, South Korea 55685936600; 59413019100; 59544177600; 59544316300; 57346636700; 59543763900; 16642183100 roy.b.chung@knu.ac.kr; CRYSTAL GROWTH & DESIGN CRYST GROWTH DES 1528-7483 1528-7505 25 4 SCIE CHEMISTRY, MULTIDISCIPLINARY;CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY 2024 3.4 14.5 0 2025-05-07 0 0 RECENT PROGRESS; THIN-FILMS; GROWTH; BETA-GA2O3; GA2O3 Annealing; Gallium compounds; Hall mobility; Semiconductor doping; Electrical and structural properties; F-doping; Fluorine-doped; Metal contacts; Metastables; Ohmic behaviour; Single phasis; Sn-doped; Thermal; Ti-based; Sapphire English 2025 2025-02-05 10.1021/acs.cgd.4c01372 바로가기 바로가기 바로가기 바로가기
Article Blood pressure management based on infarct volume after successful endovascular thrombectomy Introduction: While the efficacy of endovascular thrombectomy (EVT) in large core infarcts has been established, the influence of blood pressure (BP) management on functional outcomes based on infarct volume remains unclear. Patients and methods: We conducted a secondary analysis of the Outcome in Patients Treated With Intra-Arterial Thrombectomy–Optimal Blood Pressure Control (OPTIMAL-BP) trial, which compared intensive (systolic BP 50 ml group. The conventional management was significantly associated with a higher rate of functional independence in the infarct volume ⩽50 ml group (adjusted odds ratio [AOR], 2.06 [95% CI, 1.12–3.86]). In the infarct volume >50 ml group, the proportion of patients with functional independence was not significantly different between BP managements (AOR, 1.52 [95% CI, 0.46–5.04]). The interaction effect between the infarct volume groups and BP managements was not significant. As infarct volume increased, the difference in predicted probability of functional independence between BP managements decreased. Discussion and conclusions: Conventional BP management showed greater benefits for achieving functional independence at 3 months when infarct volumes were smaller. As infarct volume increased, the impact of BP management strategies on functional outcomes decreased. Registration: ClinicalTrials.gov (NCT04205305) © European Stroke Organisation 2025. Jung, Jae Wook; Kim, Kwang Hyun; Yun, Jaeseob; Joo, Haram; Kim, Young Dae; Heo, JoonNyung; Lee, Hyungwoo; Kim, Byung Moon; Kim, Dong Joon; Shin, Na Young; Cho, Bang-Hoon; Ahn, Seong Hwan; Park, Hyungjong; Sohn, Sung-Il; Hong, Jeong-Ho; Song, Tae-Jin; Chang, Yoonkyung; Kim, Gyu Sik; Seo, Kwon-Duk; Lee, Kijeong; Chang, Jun Young; Seo, Jung Hwa; Lee, Sukyoon; Baek, Jang-Hyun; Cho, Han-Jin; Shin, Dong Hoon; Kim, Jinkwon; Yoo, Joonsang; Baik, Minyoul; Jung, Yo Han; Hwang, Yang-Ha; Kim, Chi Kyung; Kim, Jae Guk; Lee, Il Hyung; Choi, Jin Kyo; Lee, Chan Joo; Park, Sungha; Jeon, Soyoung; Lee, Hye Sun; Kwon, Sun U; Bang, Oh Young; Heo, Ji Hoe; Nam, Hyo Suk Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea, Department of Neurology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea, Department of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea; Department of Radiology, Yonsei University College of Medicine, Seoul, South Korea; Department of Radiology, Yonsei University College of Medicine, Seoul, South Korea; Department of Radiology, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Korea University Anam Hospital, College of Medicine, Seoul, South Korea; Department of Neurology, Chosun University School of Medicine, Gwangju, South Korea; Department of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; Department of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; Department of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; Department of Neurology, Seoul Hospital, Ewha Woman’s University, College of Medicine, Seoul, South Korea; Department of Neurology, Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, South Korea; National Health Insurance Service Ilsan Hospital, Goyang, South Korea; National Health Insurance Service Ilsan Hospital, Goyang, South Korea; National Health Insurance Service Ilsan Hospital, Goyang, South Korea; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, South Korea; Department of Neurology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea; Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Neurology, Pusan National University School of Medicine, Busan, South Korea; Department of Neurology, Gachon University Gil Medical Center, Incheon, South Korea; Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, South Korea; Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, South Korea; Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, South Korea; Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Neurology, Korea University Guro Hospital and College of Medicine, Seoul, South Korea; Department of Neurology, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejon, South Korea; Department of Neurology, Kyung Hee University Hospital at Gangdong, Seoul, South Korea; Department of Neurology, Seoul Medical Center, Seoul, South Korea; Department of Health Promotion, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; Department of Health Promotion, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea, Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, South Korea; Department of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, South Korea; Department of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea 57217003257; 57191527009; 58905434900; 58665101900; 56153946300; 57219861395; 57209973874; 49861594200; 55508933800; 56363572300; 55171752400; 59683320400; 57199865406; 59682945500; 55931654800; 55507164200; 56525550900; 58431244000; 59668707400; 58995258200; 59683246100; 59659772200; 57217310224; 56066538700; 59683170000; 59683170100; 37090736900; 55261162200; 57197951986; 56610502000; 7402311308; 56701057800; 59088002100; 57394223800; 57215910153; 56812485300; 8556278400; 57223622373; 59658307600; 7402624264; 59668774400; 34869576000; 59657880300 hsnam@yuhs.ac; European Stroke Journal EUR STROKE J 2396-9873 2396-9881 SCIE CLINICAL NEUROLOGY;PERIPHERAL VASCULAR DISEASE 2024 4.5 14.6 N/A 0 antihypertensives; blood pressure; cerebral infarction volume; Endovascular thrombectomy English Article in press 2025 10.1177/23969873251335204 바로가기 바로가기 바로가기
Article Random Walk with Heterogeneous Sojourn Time We introduce a discrete-time random walk model on a one-dimensional lattice with a nonconstant sojourn time and prove that the discrete density converges to a solution of a continuum diffusion equation. Our random walk model is not Markovian due to the heterogeneity in the sojourn time, unlike a random walk model with a nonconstant walk length. We derive a Markovian process by choosing appropriate subindexes of the time-space grid points and then show the convergence of its discrete density through the parabolic-scale limit. We also find Green’s function of the continuum diffusion equation and present three Monte Carlo simulations to validate the random walk model and the diffusion equation. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025. Chung, Jaywan; Kim, Yong-Jung; Lee, Min-Gi Energy Conversion Research Center, Korea Electrotechnology Research Institute, 12, Jeongiui-gil, Gyeongsangnam-do, Changwon-si, 51543, South Korea; Department of Mathematical Sciences, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea; Department of Mathematics, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu, 41566, South Korea 35387884100; 55154687400; 36704125500 leem@knu.ac.kr; Journal of Dynamics and Differential Equations J DYN DIFFER EQU 1040-7294 1572-9222 SCIE MATHEMATICS, APPLIED;MATHEMATICS 2024 1.3 14.6 0 2025-05-07 1 English Article in press 2025 10.1007/s10884-025-10409-7 바로가기 바로가기 바로가기
Article The Moderating Role of Homophily and Need for Uniqueness in the Relationship Between Anthropomorphism of Virtual Influencer and Intention to Imitate and Word of Mouth With the recent gradual reduction in negative perceptions of virtual influencers (VIs), understanding how consumers perceive VIs’ anthropomorphism and its impact on forming consumer relationships is critical for increasing marketing effectiveness. To gain a better understanding of how consumers form relationships with VIs, this study examined VI characteristics as well as consumer personalities. The study’s data were collected from a sample of 266 social media users. The results show that VI’s anthropomorphism positively affected the parasocial relationship (PSR). This association was reinforced by homophily, whereas the neede for uniqueness dampened it. PSR positively influenced trust, intention to imitate, and word-of-mouth (WOM). Moreover, trust positively affected imitation intention and WOM. This study aimed to broaden theoretical understanding, specifically on consumers’ responses to VIs, which is an emerging research area, while providing practical recommendations for companies incorporating VIs into their strategies. © 2025 Taylor & Francis Group, LLC. Lee, Jihyeon; Kim, Hanku School of Business Administration, Kyungpook National University, Daegu, South Korea; School of Business Administration, Kyungpook National University, Daegu, South Korea 57284597800; 57195427228 hangu19@knu.ac.kr; International Journal of Human-Computer Interaction INT J HUM-COMPUT INT 1044-7318 1532-7590 SCIE;SSCI COMPUTER SCIENCE, CYBERNETICS;ERGONOMICS 2024 4.9 14.6 0 2025-05-07 0 Anthropomorphism; homophily; intention to imitate; need for uniqueness; parasocial relationship; trust; word-of-mouth Abiotic; % reductions; Anthropomorphism; Consumer Response; Homophily; Intention to imitate; Need for uniqueness; Parasocial relationship; Research areas; Social media; Trust; Anthropogenic English Article in press 2025 10.1080/10447318.2024.2439571 바로가기 바로가기 바로가기
Article Association Between Alcohol Consumption and the Risk of Incident Chronic Kidney Disease: A Korean Nationwide Study of Community-Dwelling Older Adults Background/Objectives: This study examined the effects of alcohol consumption on chronic kidney disease (CKD) risk in community-dwelling older adults. Methods: A nationwide retrospective observational study was conducted using NHIS-Senior cohort data (2009-2018). Adults aged >= 65 years with an estimated glomerular filtration rate (eGFR) >= 60 mL/min/1.73 m(2) were included. Alcohol consumption was classified as non-drinking, mild, moderate, or heavy drinking. CKD onset was defined as eGFR = 75 years, in males and mild drinkers aged < 85 years in females. Conclusions: This study shows that alcohol consumption is negatively associated with the risk of incident CKD in older adults, particularly among males. Sun, In O.; Lee, Hui-Seung; Lim, Chiyeon; Bae, Eunjin; Hyun, Young Youl; Chung, Sungjin; Kwon, Soon Hyo; Cho, Jang-Hee; Yoo, Kyung Don; Park, Woo Yeong; Kim, Hyunsuk; Yu, Byung Chul; Ko, Gang-Jee; Yang, Jae Won; Hwang, Won Min; Song, Sang Heon; Shin, Sung Joon; Hong, Yu Ah Presbyterian Med Ctr, Dept Internal Med, Div Nephrol, Jeonju 54987, South Korea; Dongguk Univ, Coll Med, Dept Biostat, Goyang 10326, South Korea; Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiol, Charlestown, MA 02129 USA; Gyeongsang Natl Univ, Coll Med, Dept Internal Med, Div Nephrol, Jinju, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Nephrol,Dept Internal Med, Seoul 03181, South Korea; Catholic Univ Korea, Yeouido St Marys Hosp, Dept Internal Med, Div Nephrol,Dept Internal Med, Seoul 07345, South Korea; Soonchunhyang Univ, Seoul Hosp, Dept Internal Med, Seoul Hosp, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Dept Internal Med, Div Nephrol,Dept Internal Med, Daegu 41944, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Internal Med, Div Nephrol,Coll Med, 25 Daehakbyeongwon Ro, Ulsan 44030, South Korea; Keimyung Univ, Keimyung Univ Dongsan Hosp, Dept Internal Med, Div Nephrol,Dept Internal Med, Daegu 42601, South Korea; Hallym Univ, Chuncheon Sacred Heart Hosp, Med Ctr, Div Nephrol,Med Ctr, Chunchon 24253, South Korea; Soonchunhyang Univ, Bucheon Hosp, Dept Internal Med, Bucheon Hosp, Bucheon 14584, South Korea; Korea Univ, Korea Univ Guro Hosp, Dept Internal Med, Div Nephrol,Dept Internal Med, Seoul 08308, South Korea; Yonsei Univ Wonju, Dept Internal Med, Div Cardiol, Coll Med, Wonju 26493, South Korea; Konyang Univ Hosp, Dept Internal Med, Div Nephrol, Daejeon, South Korea; Pusan Natl Univ, Sch Med, Sch Med, Yangsan 50612, South Korea; Dongguk Univ, Dongguk Univ Ilsan Hosp, Div Nephrol, Div Nephrol,Dept Internal Med, Goyang 10326, South Korea; Catholic Univ Korea, Coll Med, Daejeon St Marys Hosp, Div Nephrol,Dept Internal Med, Seoul, South Korea ; Yoo, Kyung/AAK-8096-2020 36994821600; 57221599404; 59711210200; 55880508000; 57037163300; 23388171000; 57199820603; 7403536291; 56603636300; 36344980100; 57194217507; 57203908496; 8310760600; 55038270300; 55568773500; 36162581500; 59710475400; 55125210000 inogood@hanmail.net; youbil3@naver.com; rachun@hanmail.ne; delight7607@naver.com; femur0@naver.com; chungs@catholic.ac.kr; ksoonhyo@schmc.ac.kr; jh-cho@knu.ac.kr; ykd9062@gmail.com; wy-my@hanmail.net; keeee@hanmail.net; nephroybc@schmc.ac.kr; lovesba@hanmail.net; kidney74@yonsei.ac.kr; hwangwm@kyuh.ac.kr; shsong0209@gmail.com; hine5050@naver.com; amorfati@catholic.ac.kr; NUTRIENTS NUTRIENTS 2072-6643 17 6 SCIE NUTRITION & DIETETICS 2024 5 14.7 0 2025-05-07 0 0 aged; alcohol beverages; chronic kidney disease; glomerular filtration rate; sex ETHANOL-CONSUMPTION; GENDER-DIFFERENCES; DRINKING PATTERN; FUNCTION DECLINE; METABOLISM; HEART; WINE; DEHYDROGENASE; EPIDEMIOLOGY; BEER aged; alcohol beverages; chronic kidney disease; glomerular filtration rate; sex Aged; Aged, 80 and over; Alcohol Drinking; Female; Glomerular Filtration Rate; Humans; Incidence; Independent Living; Male; Renal Insufficiency, Chronic; Republic of Korea; Retrospective Studies; Risk Factors; age; aged; alcohol consumption; Article; chronic kidney failure; cohort analysis; community dwelling person; estimated glomerular filtration rate; female; follow up; gender; glomerulus filtration rate; heavy drinker; heavy drinking; human; incidence; major clinical study; male; non-drinker; observational study; retrospective study; risk factor; adverse event; drinking behavior; epidemiology; etiology; independent living; South Korea; very elderly English 2025 2025-03-11 10.3390/nu17060983 바로가기 바로가기 바로가기 바로가기
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