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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI ⓘ FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
○ ○ Article ⓘ Magnetite double-network composite using hydroxyapatite-manganese dioxide for Sr²⁺ removal from aqueous solutions ⓘ Composites consisting of magnetic hydroxyapatite coated with manganese dioxide (mHAP@MnO2) were synthesized, and their Sr2+ adsorption capacities in aqueous solution were investigated. The results of various experiments, including adsorption isotherm, kinetics, pH effect, and competing ion adsorption experiments showed that the mHAP@MnO2 composites exhibited excellent Sr2+ removal, which could be attributed to their large specific surface area and appropriate pore size. Scanning electron microscopy coupled with energy dispersive spectroscopy (SEM-EDS), Brunauer-Emmett-Teller (BET), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and vibrating-sample magnetometer (VSM) analyzes were performed to determine the morphology, pore size, elemental content, and magnetization (11.713 emu/g) characteristics of the developed composites. The adsorption isotherm experiments revealed that the composites had a maximum adsorption capacity of 37.37 mg/g, and the Sr2+ adsorption process fitted well with the Langmuir isotherm (R-2 = 0.9380) and the pseudo-second order kinetic model (R-2 = 0.9487 at 100 ppm of Sr2+). Additionally, under a wide range (pH 3-11) of pH values, the composites remained stable and showed high Sr2+ selectivity. These results illustrate the possibility of their application in Sr2(+) removal from actual Sr2+-containing liquid wastes. ⓘ Choi, Jung-Weon; Lee, Hyun-Kyu; Choi, Sang-June ⓘ Korea Res Inst Chem Technol, Green Carbon Catalysis Ctr, 141 Gajeong Ro, Daejeon 34114, South Korea; Korea Atom Energy Res Inst, Radwaste Management Ctr, 111 Daedeok Daero, Daejeon 34057, South Korea; Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, 80 Daehak Ro, Daegu 41566, South Korea ⓘ ⓘ 56996378900; 36465457300; 56605563600 ⓘ sjchoi@knu.ac.kr; ⓘ JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING ⓘ J ENVIRON CHEM ENG ⓘ 2213-2929 2213-3437 9 4 SCIE ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL ⓘ 2021 7.968 13.6 0.76 2025-07-30 ⓘ 15 15 Adsorption; Hydroxyapatite; Magnetic; Manganese dioxide; Radionuclides; Strontium ⓘ EFFICIENT REMOVAL; STRONTIUM; ADSORPTION; CESIUM; COBALT; BLUE; MONTMORILLONITE; SEPARATION; BEADS; IONS ⓘ Adsorption; Hydroxyapatite; Magnetic; Manganese dioxide; Radionuclides; Strontium ⓘ Adsorption isotherms; Energy dispersive spectroscopy; Fourier transform infrared spectroscopy; Hydroxyapatite; Magnetite; Manganese oxide; Morphology; pH effects; Pore size; Radioisotopes; Scanning electron microscopy; Strontium; Strontium compounds; Adsorption capacities; Adsorption experiment; Brunauer emmett tellers; Energy dispersive; Ion adsorption; Large specific surface areas; Manganese dioxide; MnO$-2$; Scanning electrons; Synthesised; Adsorption ⓘ English 2021 2021-08 10.1016/j.jece.2021.105360 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Numeric Evaluation of Innovate Spring Machined Nickel-Titanium Rotary Instruments: A 3-dimensional Finite Element Study ⓘ Introduction: The purpose of this study was to investigate if machined springs in nickeltitanium (NiTi) rotary instruments can improve their mechanical properties. The bending and torsion properties were assessed using finite element (FE) model analysis. Methods: A basic 3-dimensional file model without a spring was created with apical size #25, 25-mm full length, and 16-mm cutting flutes. Three other models were created with a spring machined into their shaft portion with different numbers of spring coils: standard (STspr), 10% more (INspr), and 10% less (DEspr). To compare the mechanical responses among the 4 FE models, file bending and torsion were simulated using FE analysis. Results: Spring machined NiTi rotary instruments showed higher torsional resistance and less bending stiffness than the same instrument without. The spring machined models required more torque to bend or rotate the DEspr model than was required for the STspr and INspr models; however, the STSpr and INSpr models were similar. Conclusions: Within the limitations of this study, the FE analysis indicated that machining a spring into the shaft of NiTi rotary instruments improved torsional resistance and bending flexibility. Therefore, spring machining has the potential to increase the Introduction: The purpose of this study was to investigate if machined springs in nickel titanium (NiTi) rotary instruments can improve their mechanical properties. The bending and torsion properties were assessed using finite element (FE) model analysis. Methods: A basic 3-dimensional file model without a spring was created with apical size #25, 25-mm full length, and 16-mm cutting flutes. Three other models were created with a spring machined into their shaft portion with different numbers of spring coils: standard (STspr), 10% more (INspr), and 10% less (DEspr). To compare the mechanical responses among the 4 FE models, file bending and torsion were simulated using FE analysis. Results: Spring machined NiTi rotary instruments showed higher torsional resistance and less bending stiffness than the same instrument without. The spring machined models required more torque to bend or rotate the DEspr model than was required for the STspr and INspr models; however, the STSpr and INSpr models were similar. Conclusions: Within the limitations of this study, the FE analysis indicated that machining a spring into the shaft of NiTi rotary instruments improved torsional resistance and bending flexibility. Therefore, spring machining has the potential to increase the durability of the NiTi rotary instruments. (J Endod 2021;47:303?308.) ⓘ Kim, Na Yoon; Kwak, Sang Won; Yoon, Tae Ho; Ha, Jung-Hong; Versluis, Antheunis; Kim, Hyeon-Cheol ⓘ Pusan Natl Univ, Sch Dent, Dent Res Inst, Dept Conservat Dent, Yangsan, South Korea; Korea Inst Sci & Technol Informat, Daejeon, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Conservat Dent, Daegu, South Korea; Univ Tennessee, Coll Dent, Dept Biosci Res, Hlth Sci Ctr, Memphis, TN USA ⓘ Kim, Hyeon/AAQ-9057-2021 ⓘ 57220005687; 54787794900; 57220004124; 55549831900; 56230769700; 35746710200 ⓘ golddent@pusan.ac.kr; ⓘ JOURNAL OF ENDODONTICS ⓘ J ENDODONT ⓘ 0099-2399 1878-3554 47 2 SCIE DENTISTRY, ORAL SURGERY & MEDICINE ⓘ 2021 4.422 13.6 0.43 2025-07-30 ⓘ 3 3 Bending stiffness; finite element analysis; nickel-titanium rotary file; spring machining; torsional resistance ⓘ ⓘ Bending stiffness; finite element analysis; nickel-titanium rotary file; spring machining; torsional resistance ⓘ Dental Alloys; Equipment Design; Finite Element Analysis; Materials Testing; Nickel; Root Canal Preparation; Stress, Mechanical; Titanium; Torsion, Mechanical; dental alloy; nickel; titanium; equipment design; finite element analysis; materials testing; mechanical stress; mechanical torsion; root canal preparation ⓘ English 2021 2021-02 10.1016/j.joen.2020.10.015 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ On the Design of Mutual Authentication and Key Agreement Protocol in Internet of Vehicles-Enabled Intelligent Transportation System ⓘ Internet of Vehicles (IoV), a distributed network involving connected vehicles and Vehicular Ad Hoc Networks (VANETs), allows connected vehicles to communicate with other Internet-connected entities in real time. The communications among these entities (e.g. vehicles, pedestrians, fleet management systems, and road-side infrastructure) generally take place via an open channel. In other words, such an open communication can be targeted by the adversary to eavesdrop, modify, insert fabricated (or malicious) messages, or delete any data-in-transit; thus, resulting in replay, impersonation, man-in-the-middle, privileged-insider, and other related attacks. In addition to security, anonymity and untraceability are two other important features that should be achieved in an authentication protocol. In this paper, we propose a new mutual authentication and key agreement protocol in an IoV-enabled Intelligent Transportation System (ITS). Using both formal and informal security analysis, as well as formal security verification using an automated verification tool, we show that the proposed scheme is secure against several known attacks in an IoV-enabled ITS environment. Furthermore, a detailed comparative analysis shows that the proposed scheme has low communication and computational overheads, and offers better security and functionality attributes in comparison to seven other competing schemes. We also evaluate the performance of the proposed scheme using NS2. ⓘ Bagga, Palak; Das, Ashok Kumar; Wazid, Mohammad; Rodrigues, Joel J. P. C.; Choo, Kim-Kwang Raymond; Park, YoungHo ⓘ Int Inst Informat Technol, Ctr Secur Theory & Algorithm Res, Hyderabad 500032, India; Graph Era, Dept Comp Sci & Engn, Dehra Dun 248002, Uttarakhand, India; Fed Univ Piaui UFPI, BR-64049550 Teresina, Brazil; Inst Telecomunicacoes, Porto, Portugal; Inst Telecomunicacoes, Barcelona, Spain; Univ Texas San Antonio, Dept Elect & Comp Engn, Dept Informat Syst & Cyber Secur, San Antonio, TX 78249 USA; Univ Texas San Antonio, Dept Comp Sci, San Antonio, TX 78249 USA; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea ⓘ wazid, mohammad/X-4211-2018; Das, Ashok Kumar/U-2790-2019; WAZID, MOHAMMAD/X-4211-2018; Rodrigues, Joel/A-8103-2013; Choo, Kim-Kwang Raymond/A-3634-2009 ⓘ 57211317635; 55450732800; 55480987400; 25930566300; 57208540261; 56962990300 ⓘ palak.bagga@research.iiit.ac.in;iitkgp.akdas@gmail.com;wazidkec2005@gmail.com;joeljr@ieee.org;raymond.choo@fulbrightmail.org;parkyh@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY ⓘ IEEE T VEH TECHNOL ⓘ 0018-9545 1939-9359 70 2 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS;TRANSPORTATION SCIENCE & TECHNOLOGY ⓘ 2021 6.239 13.6 8.17 2025-07-30 ⓘ 102 124 Authentication; Security; Protocols; Biological system modeling; Vehicular ad hoc networks; Vehicle dynamics; Privacy; AVISPA; Internet of Vehicles (IoV); intelligent transportation system (ITS); authentication; key management; NS2 simulation; security ⓘ SCHEME; SECURITY ⓘ authentication; AVISPA, Internet of Vehicles (IoV); intelligent transportation system (ITS); key management; NS2 simulation; security ⓘ Authentication; Fleet operations; Intelligent systems; Intelligent vehicle highway systems; Network security; Security systems; Vehicle to vehicle communications; Vehicles; Authentication protocols; Automated verification; Comparative analysis; Computational overheads; Fleet management system; Intelligent transportation systems; Mutual authentication; Vehicular Adhoc Networks (VANETs); Vehicular ad hoc networks ⓘ English 2021 2021-02 10.1109/tvt.2021.3050614 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Optimization and modeling of efficient photocatalytic TiO2-ZnO composite preparation parameters by response surface methodology ⓘ The major focus of this work is the design and optimization of the preparation conditions of binary titanium dioxide-zinc oxide (TiO2-ZnO) composite using response surface methodology (RSM). Calcination temperature and ZnO weight percent (%) with respect to TiO2 were chosen as the key parameters for optimizing the preparation conditions. The evaluation of photocatalytic nitrogen oxides (NOx) removal efficiency was selected for modeling the RSM. Thirteen factorial design runs were first generated with one replicate and 5 center points in order to perform all the experiments. The experimental results on NOx removal efficiency for the composites calcined at 747, 602, and 558 degrees C containing 5.48%, 3.48%, and 2.1% of ZnO with respect to the weight of TiO2, designated as MaxT(Z%), MedT(Z%) and MinT(Z%) respectively, agree well with RSM predictions. The response coefficient difference between experimental and RSM results of MaxT(Z%), MedT(Z%), and MinT(Z%) were approximately 0.019, 0.044, and 0.11, respectively. The microstructural and optical properties as well the surface composition of MaxT(Z%), MedT(Z%), and MinT(Z%) were evaluated by X-ray diffraction (XRD), diffuse reflectance spectroscopy (DRS), and X-ray photoelectron spectroscopy (XPS), respectively. The results from the photodecomposition of NOx gas under illuminated UV-light confirmed that the TiO2-ZnO prepared with a 2.1 wt % of ZnO and calcined at 558 degrees C witnessed the best photocatalytic activity and the reasons for the excellent performance are corroborated with XRD, XPS, and DRS results. This study provides a simple and systematic approach for the optimization and modeling of the binary composite preparation for achieving enhanced photoactivity. ⓘ Kighuta, Kabuyaya; Gopalan, Anantha-Iyengar; Lee, Dong-Eun; Saianand, Gopalan; Hou, Yao-Long; Park, Sung-Sik; Lee, Kwang-Pill; Lee, Jun-Cheol; Kim, Wha-Jung ⓘ Kyungpook Natl Univ, Dept Civil Engn, Daegu 41566, South Korea; GOONWORLD Corp Res Inst, Dong Gu Inovalley 26 Rd 9-115, Daegu 41566, South Korea; Kyungpook Natl Univ, Intelligent Construct Automat Ctr, Daegu 41566, South Korea; Univ Newcastle, Coll Engn Sci & Environm, Global Ctr Environm Remediat GCER, Callaghan, NSW 2308, Australia; Zhengzhou Railway Vocat & Tech Coll, Coll Railway Engn, Zhengzhou 451460, Henan, Peoples R China; Seowon Univ, Dept Architecture, Cheongju 28674, South Korea ⓘ Gopalan, Saianand/J-6000-2019; Hou, Yaolong/KRP-4300-2024 ⓘ 57194062365; 57191999779; 56605563300; 38362265400; 57210563078; 36241850300; 8382891300; 55694062800; 57203533494 ⓘ sungpark@knu.ac.kr;kimwj@knu.ac.kr; ⓘ JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING ⓘ J ENVIRON CHEM ENG ⓘ 2213-2929 2213-3437 9 6 SCIE ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL ⓘ 2021 7.968 13.6 0.7 2025-07-30 ⓘ 13 14 TiO2-ZnO; Response surface design; Optimization; Photo-degradation; Nitrogen oxide ⓘ THIN-FILMS; ELECTRONIC-STRUCTURE; OPTICAL-PROPERTIES; SOLAR-CELLS; ZNO FILMS; TI; DEGRADATION; NANOPARTICLES; OXIDATION; LAYER ⓘ Nitrogen oxide; Optimization; Photo-degradation; Response surface design; TiO<sub>2</sub>-ZnO ⓘ Calcination; Efficiency; II-VI semiconductors; Nitrogen oxides; Nitrogen removal; Optical properties; Photocatalytic activity; Surface properties; X ray diffraction; X ray photoelectron spectroscopy; Zinc oxide; Nitrogen oxides removal; Optimisations; Photo degradation; Photo-catalytic; Preparation conditions; Removal efficiencies; Response surface designs; Response-surface methodology; TiO2-ZnO; X- ray diffractions; Titanium dioxide ⓘ English 2021 2021-12 10.1016/j.jece.2021.106417 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Removal of Cu²⁺, Cd²⁺, and Pb²⁺ from aqueous solution by fabricated MIL-100(Fe) and MIL-101(Cr): Experimental and molecular modeling study ⓘ In this study, two metal-organic frameworks [MIL-100(Fe) and MIL-101(Cr)] are fabricated and investigated to determine their ability to remove Cu2+, Cd2+, and Pb2+ from aqueous solution. MIL-100(Fe) and MIL-101(Cr) exhibited fast adsorption kinetics, achieving equilibrium in approximately 0.5 h. To evaluate the adsorption capacities of MIL-100(Fe) and MIL-101(Cr), the experimental data was fit to the Linear, Freundlich, and Langmuir isotherm models. Based on the sum of the squared error analysis, the experimental data fit most closely to the Freundlich model, followed closely by the Linear isotherm model. However, the values for the Freundlich parameter n were close to 1, which suggests that the adsorption followed the Linear isotherm model. The K-LIN adsorption affinity coefficient [(mg/g)/(mg/L)] for the Linear isotherm model was the largest for Cu2+ (K-LIN,K- MIL100(Fe) = 14.9; K-LIN,K- MIL-101(Cr) = 60.3), followed by Cd2+ (K-LIN,K- MIL-100(Fe) = 12.9; K-LIN,K- MIL-101(Cr) = 11.5) and Pb2+ (K-LIN,K- MIL-100(Fe) = 4.44; K-LIN,K- (MIL-101(Cr)) = 8.33). Characterization data of MIL-100(Fe) and MIL-101(Cr) showed specific surface areas of 1586 m(2)/g and 2505 m(2)/g for MIL-100(Fe) and MIL-101(Cr), respectively, along with the presence of various functional groups, including carboxyl and phenyl groups. Considering this data alongside the local energy decomposition analysis that was performed using molecular modeling, electrostatic interactions were determined to be the dominant adsorption mechanism for the removal of Cu2+, Cd2+, and Pb2+ by MIL-100 (Fe) and MIL-101(Cr), which is consistent with other, similar adsorption studies. This study shows that MIL-100 (Fe) and MIL-101(Cr) are effective adsorbents for the removal of heavy metals from aqueous solution. ⓘ Joseph, Lesley; Saha, Moutoshi; Kim, Sewoon; Jun, Byung-Moon; Heo, Jiyong; Park, Chang Min; Jang, Min; Flora, Joseph R., V; Yoon, Yeomin ⓘ Univ South Carolina, Dept Civil & Environm Engn, Columbia, SC 29201 USA; Korea Atom Energy Res Inst KAERI, Radwaste Management Ctr, 111 Daedeok Daero 989beon Gil, Daejeon 34057, South Korea; Korea Army Acad, Dept Civil & Environm Engn, Young Cheon 38900, Gyeongbuk, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kwangwoon Univ, Dept Environm Engn, 447-1 Wolgye Dong Nowon Gu, Seoul, South Korea ⓘ Jang, Min/M-6690-2018; Park, Chang Min/CAA-8506-2022; Yoon, Yeomin/KDP-2253-2024; Saha, Moutoshi/AAD-7036-2022; Jang, Min/J-2230-2012; Jun, Byung-Moon/Y-2134-2019 ⓘ 39261729300; 57202773164; 57201422323; 55326699900; 42461338400; 57209588953; 36762550700; 7006804321; 7402126688 ⓘ flora@cec.sc.edu;yoony@cec.sc.edu; ⓘ JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING ⓘ J ENVIRON CHEM ENG ⓘ 2213-2929 2213-3437 9 6 SCIE ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL ⓘ 2021 7.968 13.6 1.05 2025-07-30 ⓘ 25 25 Metal-organic frameworks; Adsorption; Heavy metals; Water treatment; Molecular modeling ⓘ METAL-ORGANIC FRAMEWORKS; PERSONAL CARE PRODUCTS; ADSORPTIVE REMOVAL; BASIS-SETS; WATER; EFFICIENT; PHOTOCATALYST; WASTE; SITES ⓘ Adsorption; Heavy metals; Metal-organic frameworks; Molecular modeling; Water treatment ⓘ Adsorption isotherms; Chemicals removal (water treatment); Fabrication; Heavy metals; Metal-Organic Frameworks; Molecular modeling; Organometallics; Adsorption capacities; Adsorption kinetics; Freundlich and Langmuir isotherms; Freundlich isotherm model; Isotherm modeling; Linear Freundlich isotherm; Linear isotherms; Metalorganic frameworks (MOFs); MIL-100; Molecular modeling studies; Adsorption ⓘ English 2021 2021-12 10.1016/j.jece.2021.106663 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Robust Authentication Protocol for Dynamic Charging System of Electric Vehicles ⓘ Electric vehicles have emerged as the future of transport worldwide with the rising need for greener and energy-efficient transportation solutions. This remarkable shift delegated a wide variety of protocols for reliable, scalable and secure communications in the electric vehicle transportation system. With this vision in mind, security researchers have proposed diverse authentication protocols vital for the electric vehicle charging system to protect the information exchanged between the various principals involved. Several existing authentication techniques, on the other hand, are either vulnerable to significant security threats or are limited to static charging. This article proposes a robust authentication mechanism for charging electric vehicles while driving, a scenario that is rapidly approaching in the future. The proposed protocol makes use of secure and lightweight primitives such as elliptic curves and hash functions. The proposed protocol's security is being analyzed to demonstrate that it is capable of withstanding relevant attacks. Additionally, the protocol achieves its objectives at a cost that is practically conceivable in terms of transmission and computing. ⓘ Babu, Ponnuru Raveendra; Amin, Ruhul; Reddy, Alavalapati Goutham; Das, Ashok Kumar; Susilo, Willy; Park, YoungHo ⓘ Natl Inst Technol Andhra Pradesh, Dept Comp Sci & Engn, Tadepalligudem 534101, Andhra Pradesh, India; Int Inst Informat Technol, Dept Comp Sci & Engn, Naya Raipur 493661, Chhattisgarh, India; Int Inst Informat Technol, Ctr Secur Theory & Algorithm Res, Hyderabad 500032, Telangana, India; Univ Wollongong, Inst Cybersecur & Cryptol, Wollongong, NSW 2522, Australia; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea ⓘ ; Das, Ashok Kumar/U-2790-2019; Raveendra Babu, Ponnuru/GWC-9784-2022; ALAVALAPATI, GOUTHAM REDDY/AGN-0905-2022; Ponnuru, Raveendra Babu/GWC-9784-2022; Alavalapati, Goutham Reddy/AGN-0905-2022; Susilo, Willy/A-3724-2008; Amin, Ruhul/AAQ-3893-2020 ⓘ 57210586556; 57210228243; 57189311304; 55450732800; 6602119732; 56962990300 ⓘ raveendrababup@gmail.com;amin_ruhul@live.com;goutham.ace@gmail.com;iitkgp.akdas@gmail.com;wsusilo@uow.edu.au;parkyh@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY ⓘ IEEE T VEH TECHNOL ⓘ 0018-9545 1939-9359 70 11 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS;TRANSPORTATION SCIENCE & TECHNOLOGY ⓘ 2021 6.239 13.6 2.33 2025-07-30 ⓘ 35 38 Authentication; Security; Protocols; Vehicle dynamics; Electric vehicle charging; Privacy; Charging stations; Authentication; key agreement; electric vehicles; dynamic charging; security; privacy ⓘ PROVABLY-SECURE; SCHEME; INTERNET; TOOL ⓘ Authentication; dynamic charging; electric vehicles; key agreement; privacy; security ⓘ Charging (batteries); Electric vehicles; Energy efficiency; Hash functions; Charging station; Charging systems; Dynamic charging; Electric vehicle charging; Key agreement; Privacy; Security; Vehicle's dynamics; Authentication ⓘ English 2021 2021-11 10.1109/tvt.2021.3116279 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Sum Secrecy Spectral Efficiency Maximization in Downlink MU-MIMO: Colluding Eavesdroppers ⓘ In this paper, we consider a single-cell downlink multi-user multi-input multi-output (MU-MIMO) system in which multiple eavesdroppers coexist. The eavesdroppers overhear confidential information sent from a base station (BS). In particular, we assume a scenario of colluding eavesdroppers in which they cooperate with each other to decode the information. We develop a secure linear precoding method that maximizes the sum secrecy spectral efficiency. To this end, we formulate an optimization problem and propose a computationally-efficient algorithm that achieves a sub-optimal stationary point of the problem. Simulation results validate the proposed algorithm. The proposed method possesses several benefits: i) it is applicable in general systems, for example, an arbitrary number of eavesdroppers and confidential information set, ii) the associated complexity is relatively low, and iii) it is also applicable when only channel covariance of the eavesdroppers is available. ⓘ Choi, Jinseok; Park, Jeonghun ⓘ Ulsan Natl Inst Sci & Technol UNIST, Dept Elect Engn, Ulsan 44919, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Coll IT Engn, Daegu 41566, South Korea ⓘ Choi, Jinseok/AAL-6383-2020 ⓘ 57190581671; 57853652900 ⓘ jinseokchoi@unist.ac.kr;jeonghun.park@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY ⓘ IEEE T VEH TECHNOL ⓘ 0018-9545 1939-9359 70 1 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS;TRANSPORTATION SCIENCE & TECHNOLOGY ⓘ 2021 6.239 13.6 1.24 2025-07-30 ⓘ 18 21 Precoding; Downlink; Antennas; Optimization; Linear programming; Transforms; Physical layer security; Colluding eavesdroppers; generalized power iteration; MU-MIMO; secrecy rate; stationary point ⓘ ⓘ Colluding eavesdroppers; generalized power iteration; MU-MIMO; secrecy rate; stationary point ⓘ MIMO systems; Colluding eavesdroppers; Computationally efficient; Confidential information; Multi input multi output; Optimization problems; Spectral efficiencies; Spectral efficiency maximizations; Stationary points; Efficiency ⓘ English 2021 2021-01 10.1109/tvt.2020.3048736 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Review ⓘ The ACC deaminase-producing plant growth-promoting bacteria: Influences of bacterial strains and ACC deaminase activities in plant tolerance to abiotic stress ⓘ Global climate change results in frequent occurrences and/or long durations of abiotic stress. Field grown plants are affected by abiotic stress, and they modulate ethylene in response to abiotic stress exposure and use it as a signaling molecule in stress tolerance mechanisms. However, frequent occurrences and/or long durations of stress conditions can cause plants to induce ethylene levels higher than their thresholds, resulting in a reduction of plant growth and crop productivity. The use of plant growth-promoting bacteria (PGPB) that produce 1-aminocyclopropane-1-carboxylate (ACC) deaminase has increased in various plant species to ameliorate the deleterious effects of stress-induced ethylene and promote plant growth despite abiotic stress conditions. Unfortunately, there are restrictions that limit the use of ACC deaminase-producing PGPB to protect plants from abiotic stresses. This review describes how abiotic stress induces ethylene and how stress-induced ethylene adversely affects plant growth. In addition, this review emphasizes the importance of the compatibility of PGPB strains and specific host plants and ACC deaminase activities in the reduction of stress ethylene and the promotion of plant growth, based on the research published in the last 10 years. Moreover, due to the restrictions in PGPB use, this review highlights the potential generation of transgenic plants expressing the AcdS gene that encodes the ACC deaminase enzyme as a substitute for PGPB in the future to support and uplift agricultural sustainability and food security globally. ⓘ Naing, Aung Htay; Maung, The-Thiri; Kim, Chang Kil ⓘ Kyungpook Natl Univ, Dept Hort, Daegu 41566, South Korea; Kongju Natl Univ, Dept Food Sci & Technol, Yesan, South Korea ⓘ Naing, Aung Htay/AAF-4277-2019 ⓘ 37112768100; 57211713919; 7409880701 ⓘ ckkim@knu.ac.kr; ⓘ PHYSIOLOGIA PLANTARUM ⓘ PHYSIOL PLANTARUM ⓘ 0031-9317 1399-3054 173 4 SCIE PLANT SCIENCES ⓘ 2021 5.081 13.6 1.39 2025-07-30 ⓘ 52 56 ⓘ 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DEAMINASE; INDUCED ETHYLENE PRODUCTION; HIGH-TEMPERATURE STRESS; CANOLA BRASSICA-NAPUS; RICE SEEDLING GROWTH; SALT TOLERANCE; TRANSGENIC CANOLA; TOMATO PLANTS; MOLECULAR CHARACTERIZATION; SALINITY TOLERANCE ⓘ ⓘ Bacteria; Carbon-Carbon Lyases; Plant Development; Stress, Physiological; 1-aminocyclopropane-1-carboxylate deaminase; lyase; bacterium; genetics; physiological stress; plant development ⓘ English 2021 2021-12 10.1111/ppl.13545 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Torsional Resistance of WaveOne Gold and Reciproc Blue according to the Loading Methods ⓘ Introduction: This study aimed to compare the torsional resistances and fracture modes of WaveOne Gold (Dentsply Sirona, Ballaigues, Switzerland) and Reciproc Blue (VDW, Munich, Germany) using the repetitive torsional loading (RTL) method and the conventional single-rotation (STL) method. Methods: A 3-mm file tip was fixed with a brass plate, and a torsional load was applied using a custom device. In the RTL method, the file was driven counter-clockwise at 50 rpm until it achieved the preset torque of 0.5 Ncm; thereafter, it was returned to its original position. This recovery of the file to its original position was defined as 1 torsional loading cycle; the number of repetitive load cycles until fracture was counted. In the STL method, the files were rotated at a constant rate of 2 rpm in a counterclockwise direction until file fracture. The fragments fractured by the 2 methods were compared under a scanning electron microscope to examine the topographic features of the fractured surfaces and longitudinal aspects. Results: With the RTL method, Reciproc Blue showed a higher number of repetitive load cycles until fracture than WaveOne Gold (P < .05). With the STL method, Reciproc Blue also had a higher ultimate strength than WaveOne Gold (P < .05). Scanning electron microscopic findings of the fractured specimens from the 2 test methods showed different features of torsional failure. Conclusions: Within the study limitations, both the RTL and STL methods conferred similar torsional resistance. Therefore, the clinically relevant RTL method with repetitive and reciprocation motion can be used for testing torsional resistance. ⓘ Kwak, Sang Won; Abu-Tahun, Ibrahim H.; Ha, Jung-Hong; Kim, Hyeon-Cheol ⓘ Pusan Natl Univ, Dent Res Inst, Dent & Life Sci Inst, Dept Conservat Dent,Sch Dent, Yangsan, South Korea; Univ Jordan, Sch Dent, Dept Conservat Dent, Amman, Jordan; Kyungpook Natl Univ, Sch Dent, Dept Conservat Dent, Daegu, South Korea ⓘ ; Kim, Hyeon/AAQ-9057-2021 ⓘ 54787794900; 55637596300; 55549831900; 35746710200 ⓘ golddent@pusan.ac.kr; ⓘ JOURNAL OF ENDODONTICS ⓘ J ENDODONT ⓘ 0099-2399 1878-3554 47 1 SCIE DENTISTRY, ORAL SURGERY & MEDICINE ⓘ 2021 4.422 13.6 0.72 2025-07-30 ⓘ 5 5 Fracture; microscopic features; nickel-titanium file; reciprocating; repetitive; torsional load ⓘ NICKEL-TITANIUM INSTRUMENTS; CLINICAL-USE; THERMOMECHANICAL TREATMENT; FATIGUE RESISTANCE; CURRENT CHALLENGES; ROTARY; DEFECTS; FILES ⓘ Fracture; microscopic features; nickel-titanium file; reciprocating; repetitive; torsional load ⓘ Dental Instruments; Equipment Design; Germany; Gold; Materials Testing; Root Canal Preparation; Rotation; Titanium; Torque; gold; titanium; dental device; equipment design; Germany; materials testing; root canal preparation; rotation; torque ⓘ English 2021 2021-01 10.1016/j.joen.2020.09.011 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Training Length Adaptation for Reinforcement Learning-Based Detection in Time-Varying Massive MIMO Systems With One-Bit ADCs ⓘ This study elucidates a reinforcement learning (RL)-based detection with one-bit analog-to-digital converters (ADCs) in time-varying massive multiple-input and multiple-output channels. In one-bit ADCs, conventional channel estimation exhibits poor performance owing to nonlinear quantization. The RL-based detection alleviates this degradation by learning the true likelihood probability during data transmission. However, in time-varying channels, the learned likelihood probability is inconsistent with the true likelihood probability due to temporal channel variations. This inconsistency can cause severe performance degradation. To effectively exploit the learned likelihood probability, we propose a training length adaptation method that determines an appropriate training length based on the channel conditions. To achieve this, we consider an optimization problem that minimizes the training length while guaranteeing the performance of RL-based detection. The solution of the optimization problem is obtained by an explicit form based on simple approximations, and it reveals that the optimal training length depends on the change in the likelihood probability. Simulation results demonstrate that the proposed method efficiently reduces the training length when a rapid change in likelihood probability is produced in fading channels. Moreover, this reduction contributes to improving the spectral efficiency by an avoiding undesirable learning process. Consequently, the spectral efficiency of the proposed method can be significantly increased compared to that of conventional RL-based detection. For instance, the proposed method achieves 1.76 times higher spectral efficiency than the conventional method at 30 km/h. ⓘ Kim, Tae-Kyoung; Jeon, Yo-Seb; Min, Moonsik ⓘ Mokpo Natl Univ, Dept Elect Informat & Commun Engn, Jeonnam 58554, South Korea; POSTECH, Dept Elect Engn, Gyeongbuk 37673, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea ⓘ ; Jeon, Yo-Seb/U-8637-2019 ⓘ 57216708769; 58254434200; 55386299100 ⓘ tk415kim@gmail.com;yoseb.jeon@postech.ac.kr;msmin@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY ⓘ IEEE T VEH TECHNOL ⓘ 0018-9545 1939-9359 70 7 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS;TRANSPORTATION SCIENCE & TECHNOLOGY ⓘ 2021 6.239 13.6 0.39 2025-07-30 ⓘ 3 5 Training; Data communication; Channel estimation; Optimization; Superluminescent diodes; Time-varying channels; Receivers; Massive MIMO; one-bit ADC; ML detection; adaptive transmission; reinforcement learning ⓘ CHANNEL ESTIMATION; LIMITED FEEDBACK; ARCHITECTURES ⓘ adaptive transmission; Massive MIMO; ML detection; one-bit ADC; reinforcement learning ⓘ Analog to digital conversion; Efficiency; Fading channels; MIMO systems; Optimization; Probability; Reinforcement learning; Time varying networks; Analog to digital converters; Conventional methods; Multiple input and multiple output channels; Nonlinear quantization; Optimization problems; Performance degradation; Spectral efficiencies; Temporal channel variations; Learning systems ⓘ English 2021 2021-07 10.1109/tvt.2021.3090087 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Development of a new risk stratification system for patients with newly diagnosed multiple myeloma using R-ISS and ¹⁸F-FDG PET/CT ⓘ In multiple myeloma (MM), a high number of focal lesions (FL) detected using positron emission tomography/computed tomography (PET/CT) was found to be associated with adverse prognosis. To design a new risk stratification system that combines the Revised International Staging System (R-ISS) with FL, we analyzed the data of 380 patients with newly diagnosed MM (NDMM) who underwent F-18-fluorodeoxyglucose (F-18-FDG) PET/CT upon diagnosis. The K-adaptive partitioning algorithm was adopted to define subgroups with homogeneous survival. The combined R-ISS with PET/CT classified NDMM patients into four groups: R-ISS/PET stage I (n = 31; R-ISS I with FL 3 and R-ISS II with FL 3 and R-ISS III with FL 3). The 2-year overall survival rates for stages I, II, III, and IV were 96.7%, 89.8%, 74.7%, and 50.3%. The 2-year progression-free survival rates were 84.1%, 64.7%, 40.8%, and 17.1%, respectively. The new R-ISS/PET was successfully validated in an external cohort. This new system had a remarkable prognostic power for estimating the survival outcomes of patients with NDMM. This system helps discriminate patients with a good prognosis from those with a poor prognosis more precisely. ⓘ Cho, Hee Jeong; Jung, Sung-Hoon; Jo, Jae-Cheol; Lee, Yoo Jin; Yoon, Sang Eun; Park, Sung-Soo; Kim, Do Young; Shin, Ho-Jin; Mun, Yeung-Chul; Yi, Jun Ho; Kim, Hyo Jung; Kim, Da Jung; Lee, Ho Sup; Bae, Sung Hwa; Hong, Chae Moon; Jeong, Shin Young; Min, Jung-Joon; Sohn, Sang Kyun; Min, Chang-Ki; Kim, Kihyun; Lee, Je-Jung; Moon, Joon Ho ⓘ Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Hematol Oncol, Daegu, South Korea; Chonnam Natl Univ Hwasun Hosp, Dept Hematol Oncol, Yeosu, Jeollanam Do, South Korea; Chonnam Natl Univ, Sch Med, Yeosu, Jeollanam Do, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Hematol & Oncol, Coll Med, Ulsan, South Korea; Sungkyunkwan Univ, Dept Med, Samsung Med Ctr, Sch Med, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Hematol, Coll Med, Seoul, South Korea; Pusan Natl Univ, Pusan Natl Univ Hosp, Dept Hematol Oncol, Sch Med, Busan, South Korea; Ewha Womans Univ, Dept Hematol Oncol, Med Ctr, Seoul, South Korea; Chung Ang Univ Hosp, Dept Hematol Oncol, Seoul, South Korea; Hallym Univ, Dept Hematol Oncol, Sacred Heart Hosp, Anyang, South Korea; Kosin Univ, Gosper Hosp, Dept Hematol Oncol, Busan, South Korea; Daegu Catholic Univ, Daegu Catholic Univ Hosp, Sch Med, Dept Hematol Oncol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Nucl Med, Yeosu, Jeollanam Do, South Korea ⓘ Kim, Kihyun/D-5175-2013; Kim, Yun Hak/ABF-3331-2021; KIM, JIN/I-6927-2019; Lee, Jong-Seok/J-5603-2012; Park, Young Sik/MBG-1896-2025; Jo, Jae-Cheol/CAE-9453-2022; Kim, Hyo/AAQ-3152-2020; Hyun-Jung, Kim/E-8074-2011; Lee, Jung-Hye/F-6974-2013; Yi, Jun Ho/GXZ-8144-2022; Kim, Young Hoon/F-5424-2012 ⓘ 57216754907; 55511978300; 35818309200; 57188669696; 57205167470; 57043695200; 57206099586; 16239868400; 7003363716; 24339940900; 7410139194; 57195951981; 57218103550; 56545017400; 37050876700; 36164032500; 7201920094; 13310226800; 57224962914; 57199440300; 7601478211; 56568642700; 59411319800 ⓘ drjejung@chonnam.ac.kr;jhmoon@knu.ac.kr; ⓘ BLOOD CANCER JOURNAL ⓘ BLOOD CANCER J ⓘ 2044-5385 11 12 SCIE HEMATOLOGY;ONCOLOGY ⓘ 2021 9.812 13.7 0.88 2025-07-30 ⓘ 13 15 ⓘ INTERNATIONAL STAGING SYSTEM; POSITRON-EMISSION-TOMOGRAPHY; CONSENSUS; SURVIVAL; CRITERIA; LESIONS ⓘ ⓘ Adult; Aged; Aged, 80 and over; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Positron Emission Tomography Computed Tomography; Prognosis; Risk Assessment; bortezomib; carfilzomib; cytotoxic agent; fluorodeoxyglucose f 18; immunomodulating agent; ixazomib; lenalidomide; melphalan; proteasome inhibitor; thalidomide; fluorodeoxyglucose f 18; adult; aged; algorithm; Article; autologous stem cell transplantation; cancer prognosis; cancer staging; cancer survival; clinical outcome; cohort analysis; controlled study; data analysis software; diagnostic test accuracy study; disease risk assessment; drug megadose; external validity; female; human; International Staging System; major clinical study; male; multiple myeloma; overall survival; positron emission tomography-computed tomography; progression free survival; Revised International Staging System; survival rate; survival time; middle aged; multiple myeloma; positron emission tomography-computed tomography; prognosis; risk assessment; very elderly ⓘ English 2021 2021-12-01 10.1038/s41408-021-00577-2 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Evolutionary exploration of polytypism in lead halide perovskites ⓘ The regular ABX(3) cubic perovskite structure is composed of close-packed AX(3) layers stacked along the 111 axis. An equivalent hexagonal close-packed network can also be formed, in addition to a series of intermediate polytype sequences. Internally, these correspond to combinations of face- and corner-sharing octahedral chains that can dramatically alter the physical properties of the material. Here, we assess the thermodynamics of polytypism in CsPbI3 and CsPbBr3. The total energies obtained from density functional theory are used to paramaterize an axial Ising-type model Hamiltonian that includes linear and cubic correlation terms of the pseudo-spin. A genetic algorithm is built to explore the polytype phase space that grows exponentially with the number of layers. The ground-state structures of CsPbX3 polytypes are analysed to identify features of polytypism such as the distinct arrangements of layers and symmetry forbidden sequences. A number of polytypes with low ordering energies (around thermal energy at room temperature) are predicted, which could form distinct phases or appear as stacking faults within perovskite grains. ⓘ Li, Zhenzhu; Park, Ji-Sang; Walsh, Aron ⓘ Imperial Coll London, Dept Mat, London SW7 2AZ, England; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Yonsei Univ, Dept Mat Sci & Engn, Seoul 03722, South Korea ⓘ ; Park, Ji-Sang/F-9944-2010; Walsh, Aron/A-7843-2008; Li, Zhenzhu/AAK-7744-2021 ⓘ 56384544400; 36671796300; 35315151400 ⓘ a.walsh@imperial.ac.uk; ⓘ CHEMICAL SCIENCE ⓘ CHEM SCI ⓘ 2041-6520 2041-6539 12 36 SCIE CHEMISTRY, MULTIDISCIPLINARY ⓘ 2021 9.969 13.7 0.81 2025-07-30 ⓘ 20 19 ⓘ FORMAMIDINIUM; ENERGY ⓘ ⓘ Density functional theory; Genetic algorithms; Ground state; Perovskite; Phase space methods; Thermodynamics; Close packed; Corner sharing; Cubic perovskite; Evolutionary exploration; Halide perovskites; Hexagonal close packed; Hexagonal close-packed; Perovskite structures; Polytypes; Polytypism; Lead compounds ⓘ English 2021 2021-09-28 10.1039/d1sc03098a ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells ⓘ Glioblastoma is an actively growing and aggressive brain tumor with a high propensity of recurrence. Although the surgical removal of tumor mass is the primary therapeutic option against glioblastoma, supportive pharmacotherapy is highly essential due to incredibly infiltrative characteristic of glioblastoma. Temozolomide, an FDA-approved alkylating agent, has been used as a first-line standard pharmacological approach, but several evident limitations were repeatedly reported. Despite additional therapeutic options suggested, there are no medications that successfully prevent a recurrence of glioblastoma and increase the five-year survival rate. In this study, we tested the possibility that finasteride has the potential to be developed as an anti-glioblastoma drug. Finasteride, an FDA-approved medication for the treatment of benign prostate hyperplasia and androgenic alopecia, is already known to pass through the blood-brain barrier and possess antiproliferative activity of prostate epithelial cells. We showed that finasteride inhibited the maintenance of glioma stem-like cells and repressed the proliferation of glioblastoma. Mechanistically, finasteride lowered intracellular ROS level by upregulating antioxidant genes, which contributed to inefficient beta-catenin accumulation. Downregulated beta-catenin resulted in the reduction in stemness and cell growth in glioblastoma. ⓘ Kim, Hyeon Ji; Kim, Tae-Jun; Kim, Yu Gyung; Seong, Chaeeun; Cho, Jin-Hwa; Kim, Wanil; Lee, Kyung-Ha; Kim, Do-Yeon ⓘ Kyungpook Natl Univ, Sch Dent, Dept Pharmacol, Daegu 41940, South Korea; Gyeongsang Natl Univ, Inst Hlth Sci, Dept Convergence Med Sci, Dept Biochem, Jinju 52727, South Korea; Daegu Haany Univ, Div Cosmet Sci & Technol, Gyongsan 38610, South Korea ⓘ Lee, Kyung-Ha/GRY-2640-2022; Kim, Wanil/I-7849-2015; Kim, Young-Bo/AAR-8052-2021; Kim, Do-Yeon/AET-3021-2022; Kim, Hee/AAU-6368-2021; Kim, Yong-Tae/HQZ-0240-2023 ⓘ 57216816929; 57200911346; 57221687604; 57296292000; 24167566000; 7405813437; 54967786000; 57203012542 ⓘ guswl1634@naver.com;toy5988@naver.com;cosmos0468@naver.com;qjdo@naver.com;cjinhwa@knu.ac.kr;wkim@gnu.ac.kr;kyungha.lee@dhu.ac.kr;dykim82@knu.ac.kr; ⓘ PHARMACEUTICS ⓘ PHARMACEUTICS ⓘ 1999-4923 13 9 SCIE PHARMACOLOGY & PHARMACY ⓘ 2021 6.525 13.8 0.64 2025-07-30 ⓘ 11 11 glioblastoma; finasteride; proliferation; beta-catenin ⓘ TEMOZOLOMIDE; GLIOMA; PROLIFERATION; INHIBITION ⓘ Finasteride; Glioblastoma; Proliferation; β-catenin ⓘ beta catenin; epidermal growth factor receptor; finasteride; histone H2AX; histone H3; initiation factor 4E binding protein 1; manganese superoxide dismutase; peroxiredoxin 5; protein kinase B; reactive oxygen metabolite; S6 kinase; temozolomide; transcription factor Sox2; Akt/mTOR signaling; antioxidant activity; antiproliferative activity; Article; canonical Wnt signaling; controlled study; DNA damage; gene expression; glioblastoma cell line; glioma stem cell; human; human cell; T98G cell line; U-373MG Uppsala cell line ⓘ English 2021 2021-09 10.3390/pharmaceutics13091410 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Asymmetric Reaction Pathways of Conversion-Type Electrodes for Lithium-Ion Batteries ⓘ Metal oxides have been actively explored as promising conversion-type electrode materials for lithium-ion batteries due to high deliverable capacity but are still notorious for poor cyclability, capacity fading, voltage hysteresis, and so forth. However, the fundamental reason for the undesirable properties of metal oxides behind the repetitive conversion process is still obscure. In this work, we take advantage of synchrotron X-ray techniques as well as transmission electron microscopy to monitor the structural changes during both conversion (lithiation) and reconversion (delithiation) reactions. The difference in diffusion rates of lithium and metal plays a decisive role in determining the reaction pathway. We find that lithium accommodation and extraction occur via different reaction routes: lithiation follows a kinetically driven way while delithiation adopts a route close to the thermodynamic ground state path. Thermodynamic structural evolution features the formation of an intermediate phase of Li-metal (M)-O, suggesting that lithium removal accompanies the Li/M ionic exchange and rearrangement of the oxygen framework. The slow diffusion of metal ions and the high kinetic and energy barrier for dissociating the intermediate phase are mainly responsible for uncompleted reconversion reaction, evidenced by the remaining Li-M-O phase at the end of charge. Imperfect reconversion reaction eventually limits the utilization of lithium ions over the repeated cycling. This work sheds light on structural changes occurring at metal oxides during both conversion and reconversion processes, which is strongly linked with the performances of conversion-type materials in applications. ⓘ Li, Shuang; Shadike, Zulipiya; Kwon, Gihan; Yang, Xiao-Qing; Lee, Ji Hoon; Hwang, Sooyeon ⓘ Brookhaven Natl Lab, Ctr Funct Nanomat, Upton, NY 11973 USA; Brookhaven Natl Lab, Chem Div, Upton, NY 11973 USA; Brookhaven Natl Lab, Natl Synchrotron Light Source 2, Upton, NY 11973 USA; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea ⓘ Shadike, Zulipiya/ABG-9065-2021; Lee, Ji/AAU-7285-2021; Kwon, Gihan/F-9657-2010; Hwang, Sooyeon/H-8593-2012; Lee, Ji Hoon/T-4913-2017 ⓘ 57208868911; 56088345900; 55447475400; 56146373600; 55689885200; 36859249800 ⓘ jihoonlee@knu.ac.kr;soohwang@bnl.gov; ⓘ CHEMISTRY OF MATERIALS ⓘ CHEM MATER ⓘ 0897-4756 1520-5002 33 10 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY ⓘ 2021 10.508 13.8 0.47 2025-07-30 ⓘ 8 8 ⓘ PHASE EVOLUTION; ANODE MATERIALS; NONEQUILIBRIUM LITHIATION; COBALT OXIDE; MECHANISM; NANOPARTICLES; NANOCRYSTALS; MICROSCOPY; FILMS; CO3O4 ⓘ ⓘ Electrodes; Ground state; High resolution transmission electron microscopy; Ion exchange; Metal ions; Metals; Reaction intermediates; Reaction rates; Asymmetric reaction; Conversion process; Electrode material; Intermediate phase; Reaction pathways; Structural evolution; Synchrotron x-ray technique; Voltage hysteresis; Lithium-ion batteries ⓘ English 2021 2021-05-25 10.1021/acs.chemmater.0c04466 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Comprehensive Investigation of Stereoselective Food Drug Interaction Potential of Resveratrol on Nine P450 and Six UGT Isoforms in Human Liver Microsomes ⓘ The stereoselectivity of the food drug inhibition potential of resveratrol on cytochrome P450s and uridine 5'-diphosphoglucuronosyl transferases was investigated in human liver microsomes. Resveratrol enantiomers showed stereoselective inhibition of CYP2C9, CYP3A, and UGT1A1. The inhibitions of CYP1A2, CYP2B6, and CYP2C19 by resveratrol were stereo-nonselective. The estimated K-i values determined for CYP1A2 were 13.8 and 9.2 mu M for trans- and cis-resveratrol, respectively. Trans-resveratrol noncompetitively inhibited CYP3A and UGT1A1 activities with K-i values of 23.8 and 27.4 mu M, respectively. Trans-resveratrol inhibited CYP1A2, CYP2C19, CYP2E1, and CYP3A in a time-dependent manner with K-i shift values >2.0, while cis-resveratrol time-dependently inhibited CYP2C19 and CYP2E1. The time-dependent inhibition of trans-resveratrol against CYP3A4, CYP2E1, CYP2C19, and CYP1A2 was elucidated using glutathione as a trapping reagent. This information helped the prediction of food drug interaction potentials between resveratrol and co-administered drugs which are mainly metabolized by UGT1A1, CYP1A2, CYP2C19, CYP2E1, and CYP3A. ⓘ Ji, Seung-Bae; Park, So-Young; Bae, Subin; Seo, Hyung-Ju; Kim, Sin-Eun; Lee, Gyung-Min; Wu, Zhexue; Liu, Kwang-Hyeon ⓘ BK21 Four KNU Community Based Intelligent Novel D, Daegu 41566, South Korea; Coll Pharm, Res Inst Pharmaceut Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Mass Spectrometry Based Convergence Res Inst, Daegu 41566, South Korea ⓘ ⓘ 57217827900; 57211630074; 57224532908; 57204496397; 57217828200; 57217829865; 55523767300; 55768214700 ⓘ wltmdqo2377@naver.com;soyoung561@hanmail.net;bsb960908@naver.com;h1h1103@naver.com;hjkopsty@gmail.com;lgm00179@naver.com;wuzhexue@knu.ac.kr;dstlkh@knu.ac.kr; ⓘ PHARMACEUTICS ⓘ PHARMACEUTICS ⓘ 1999-4923 13 9 SCIE PHARMACOLOGY & PHARMACY ⓘ 2021 6.525 13.8 0.73 2025-07-30 ⓘ 9 10 cytochrome P450; food drug interactions; resveratrol; stereoselectivity; uridine 5 '-diphosphoglucuronosyl transferase ⓘ IN-VITRO; TRANS-RESVERATROL; RED WINE; CYTOCHROME-P450 ENZYMES; DIFFERENTIAL INHIBITION; DEPENDENT INHIBITION; PHARMACOKINETICS; MECHANISM; GLUCURONIDATION; DEBRISOQUINE ⓘ Cytochrome P450; Food drug interactions; Resveratrol; Stereoselectivity; Uridine 5′-diphosphoglucuronosyl transferase ⓘ 4 hydroxydiclofenac; 4 hydroxymephenytoin; 6 hydroxybupropion; 6 hydroxychlorzoxazone; amfebutamone; amodiaquine; aripiprazole; chenodeoxycholic acid; chlorzoxazone; coumarin; cytochrome P450; cytochrome P450 1A2; cytochrome P450 2B6; cytochrome P450 2C19; cytochrome P450 2C9; cytochrome P450 2E1; cytochrome P450 3A; cytochrome P450 3A4; dehydronifedipine; dextromethorphan; dextrorphan; diclofenac; dopamine; drug metabolizing enzyme; estrone; firtecan; glucuronide; glucuronosyltransferase 1A1; isoprotein; mephenytoin; midazolam; mycophenolic acid; n acetylserotonin; n acetylserotonine; n desethylamodiaquine; naloxone; nifedipine; phenacetin; reduced nicotinamide adenine dinucleotide phosphate; resveratrol; s mephenytoin; tetrahydropalmatine; trifluoperazine; trimipramine; umbelliferone; unclassified drug; uridine 5' diphosphoglucuronosyl transferase; accuracy; area under the curve; Article; biotransformation; controlled study; drug interaction; drug metabolism; electrospray mass spectrometry; enzyme activity; enzyme kinetics; food drug interaction; high performance liquid chromatography; IC50; inhibition constant; isomerization; limit of quantitation; liquid chromatography-mass spectrometry; liver microsome; maximum plasma concentration; Michaelis constant; microsome; parallel reaction monitoring; pharmacokinetic parameters; protein degradation; stereoselectivity; time-dependent inhibition; ultra performance liquid chromatography ⓘ English 2021 2021-09 10.3390/pharmaceutics13091419 ⓘ 바로가기 바로가기 바로가기 바로가기
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