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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Stiffness evaluation of semi-rigid connection using steel clamps in plastic greenhouse structure | Greenhouse structures, essential for modern agriculture, often experience significant uncertainties due to varying environmental conditions, leading to frequent damage and economic losses. Accurately analysing the structural responses of these greenhouses is particularly challenging due to the difficulty in understanding the actual behaviour of connections using steel clamps. This study focuses on evaluating the stiffness and mechanical behaviour of semi-rigid connections using steel clamps in plastic greenhouses. A specialised load-deformation testing apparatus was developed to assess the relationships between force and displacement or moment and rotation for these connections with various deformation modes. The experimental results were used to model stiffness coefficients and ultimate limit loads, providing a detailed understanding of the mechanical properties of these connections. Findings reveal that steel clamps introduce complex structural behaviours that differ significantly from traditional connections, highlighting the need for advanced modelling techniques. This comprehensive analysis offers new insights into the behaviour of semi-rigid connections in greenhouse structures and underscores the importance of detailed empirical studies. The research contributes to improving the structural design and safety assessments of agricultural facilities, ensuring better resilience against environmental stresses. The outcomes are crucial for developing more effective and reliable greenhouse designs that can withstand adverse conditions, ultimately supporting sustainable agricultural practices. | Lee, Sangik; Lee, Jong-hyuk; Seo, Byung-hun; Kim, Dong-su; Kim, Dongwoo; Jo, Yerim; Choi, Won | Kyungpook Natl Univ, Coll Agr & Life Sci, Dept Agr Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea; Seoul Natl Univ, Res Inst Agr & Life Sci, Coll Agr & Life Sci, Dept Landscape Architecture & Rural Syst Engn, 1 Gwanak Ro, Seoul 08826, South Korea; Seoul Natl Univ, Coll Agr & Life Sci, Dept Landscape Architecture & Rural Syst Engn, 1 Gwanak-ro, Seoul 08826, South Korea; Seoul Natl Univ, Res Inst Agr & Life Sci, Coll Agr & Life Sci,Integrated Major Global Smart, Dept Landscape Architecture & Rural Syst Engn, 1 Gwanak Ro, Seoul 08826, South Korea | Lee, Sangik/JFS-3290-2023; Lee, Jong-Hyuk/HTQ-9685-2023 | 57218215209; 57221623269; 57329495600; 57898369900; 59152104500; 59447079200; 54412025900 | sangik@knu.ac.kr; fembem@snu.ac.kr; | BIOSYSTEMS ENGINEERING | BIOSYST ENG | 1537-5110 | 1537-5129 | 250 | SCIE | AGRICULTURAL ENGINEERING;AGRICULTURE, MULTIDISCIPLINARY | 2024 | 5.3 | 12.2 | 6.72 | 2025-05-07 | 2 | 2 | Greenhouse structure; Clamp-based connection; Semi-rigid connection; Load-deformation relationship; Stiffness modelling | BEHAVIOR; DESIGN; MODEL; STRENGTH; FRAMES | Clamp-based connection; Greenhouse structure; Load-deformation relationship; Semi-rigid connection; Stiffness modelling | Clamp-based connection; Environmental conditions; Greenhouse structure; Load deformation; Load-deformation relationship; Modern agricultures; Plastic greenhouse; Semirigid connections; Stiffness modeling; Uncertainty | English | 2025 | 2025-02 | 10.1016/j.biosystemseng.2024.11.018 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Understanding of enhanced nitrate in fine particles at agricultural sites in summer with high ammonia level☆ | Nitrate is one of the major constituents of fine particles and has not been effectively alleviated in Northeast Asia. Field measurements of various gases and the chemical composition of fine particles were conducted at two agricultural sites (cropland and livestock) in ammonia-rich environments to understand the effect of ammonia on nitric acid-nitrate partitioning using a thermodynamic model and to suggest a possible strategy to control total nitrate (i.e., nitric acid formation). High nitrate levels were observed at the agricultural sites in summer compared to those at the urban sites. It was found that high level of ammonia in summer led to increased aerosol pH and nitrate fraction. At the cropland site in summer, the daily nitrate fraction was particularly sensitive to aerosol pH, suggesting that ammonia reduction should be effective in decreasing nitrate formation via nitric acid- nitrate partitioning (with a 50% reduction in ammonia, nitrate concentration can decrease by 34%). Aerosol water content also played a significant role in determining nitrate fraction in the aerosol pH range of 2.5-3.0. It was found that the sites were under high NOx conditions, and that the reduction of OH production (daytime) and O3 (nighttime) was important for controlling total nitrate, but this is challenging due to the high contributions of background O3. It was concluded that the reduction of ammonia emissions for the control of the nitrate fraction via gas-to-particle partitioning should be important to mitigate nitrate in fine particles at agricultural sites in summer. | Kim, Joonwoo; Jang, Jiho; Oh, Dahye; Ashraf, Fawad; Lim, Ho-Jin; Park, Kihong | Gwangju Inst Sci & Technol GIST, Sch Earth Sci & Environm Engn, Gwangju 61005, South Korea; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea | ; Ashraf, Fawad/MHR-0219-2025 | 57320193600; 57212104008; 58867933800; 57190007797; 56883100200; 7408063586 | kpark@gist.ac.kr; | ENVIRONMENTAL POLLUTION | ENVIRON POLLUT | 0269-7491 | 1873-6424 | 367 | SCIE | ENVIRONMENTAL SCIENCES | 2024 | 7.3 | 12.2 | 0 | 2025-05-07 | 1 | 1 | Fine particles; Nitrate; Ammonia; Agriculture | AEROSOL MASS-SPECTROMETER; AMBIENT AIR MARGA; LONG-TERM TREND; LIQUID WATER; COLLECTION EFFICIENCIES; ATMOSPHERIC CHEMISTRY; PARTICULATE MATTER; ORGANIC NITRATES; URBAN; ACIDITY | Agriculture; Ammonia; Fine particles; Nitrate | Aerosols; Agriculture; Air Pollutants; Ammonia; Environmental Monitoring; Nitrates; Particulate Matter; Seasons; Northeast Asia; alkene; ammonia; nitrate; ammonia; nitric acid derivative; % reductions; Agricultural sites; Chemical compositions; Field measurement; Fine-particles; Measurements of; Nitrate levels; Nitric acid formation; Northeast Asia; Thermodynamic modelling; agricultural land; ammonia; chemical composition; nitrate; nitric acid; ozone; summer; agricultural land; Article; chemical composition; energy dispersive X ray fluorescence spectroscopy; Fine particle; ion chromatography; livestock; mass spectrometry; nonhuman; ozonolysis; particulate matter; pH; summer; vapor pressure; water content; aerosol; agriculture; air pollutant; environmental monitoring; procedures; season | English | 2025 | 2025-02-15 | 10.1016/j.envpol.2024.125596 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Multifunctional PDMS/Coal gasification fine slag composites for enhanced electromagnetic shielding and thermal management | Coal gasification fine slag (CGFS), a representative challenging solid waste in the coal chemical industry, has garnered significant attention due to its high carbon content and inorganic oxide components. Notably, the magnetic Fe3O4 particles are uniformly distributed within the CGFS matrix, rendering it a natural magneticdielectric composite material. Capitalizing on this unique characteristic, this study innovatively proposes the application of CGFS in the field of EMI shielding. Through a facile solution blending-hot pressing process, flexible PDMS/CGFS composites were fabricated. The results demonstrate that with a CGFS loading of 40 wt%, the composite achieves an average shielding effectiveness of 34.7 dB in the X-band, significantly surpassing the commercial standard of 20 dB. Simultaneously, the composite exhibits an absorption coefficient (A) of 0.35, effectively mitigating secondary radiation pollution. Additionally, the PDMS/CGFS composite also possesses multifunctional characteristics, including thermal conductivity, Joule heating, and photothermal conversion capabilities. Therefore, this study not only provides an innovative approach for the utilization of CGFS but also opens new research directions for developing novel multifunctional EMI shielding materials. | Wang, Shengjie; Xiao, Xinlong; Yan, Xin; He, Weiwei; Huang, Chenghan; Chen, Ling; Zhang, Hexin; Fang, Liang; Yoon, Keunbyoung | Anhui Univ Technol, Sch Chem & Chem Engn, Maanshan 243032, Anhui, Peoples R China; Qingdao Univ Sci & Technol, Key Lab Rubber Plast, Qingdao 266061, Peoples R China; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu 41566, South Korea | Xiao, Xinlong/I-6330-2012 | 59706903100; 59707108600; 57222030771; 59206510300; 59206121800; 58454409000; 25633288200; 57204863378; 59493210700 | hxzhang@ahut.edu.cn; fangliang@qust.edu.cn; kbyoon@knu.ac.kr; | FUEL | FUEL | 0016-2361 | 1873-7153 | 395 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 7.5 | 12.3 | 0 | 2025-05-07 | 1 | 1 | Coal gasification slag; Composite; Electromagnetic interference shielding; Recycling; Thermal conversion | RESIDUAL CARBON; COAL | Coal gasification slag; Composite; Electromagnetic interference shielding; Recycling; Thermal conversion | Chemical industry; Coal industry; Electromagnetic pulse; Electromagnetic shielding; Heat shielding; Magnetic shielding; Slags; Coal chemicals; Coal gasification slag; Electromagnetic interference shielding; Electromagnetics; EMI shielding; Fine slag; High carbon content; Multifunctionals; Thermal; Thermal conversion; Coal gasification | English | 2025 | 2025-09-01 | 10.1016/j.fuel.2025.135195 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Obtaining both high CO2 adsorption capacity and CO2/N2 selectivity via blocking N2 adsorption sites by grafting bulky diamine on metal-organic framework | Functionalizing metal-organic frameworks (MOFs) with alkyl amines has been employed in various studies for CO2 adsorption because of their high efficiency in CO2 capture. However, a trade-off between the high CO2 adsorption and high CO2/N-2 selectivity has been usually observed. To achieve both, we focused on reducing the amount of N-2 adsorption while maintaining the CO2 adsorption capacity of alkyl amines. In this study, a bulky diamine was grafted onto coordinatively unsaturated sites of Cr-based MOFs (MIL-101) instead of a non-bulky (normal or linear) diamine of the same length (from amine to amine). The bulky diamine blocked the N-2 adsorption sites (not useful sites for CO2 adsorption), reducing N-2 adsorption more than the non-bulky diamine. On the other hand, the CO2 adsorption amount remained unchanged, especially under low pressure ( 1 mmolg(-1)) and large CO2/N-2 selectivity (> 100) at 100 kPa and 298 K. | Lee, Gyudong; Jhung, Sung Hwa | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea | Jhung, Sung/AAO-6683-2021 | 57200987600; 6701659467 | sung@knu.ac.kr; | FUEL | FUEL | 0016-2361 | 1873-7153 | 394 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 7.5 | 12.3 | 0 | 2025-05-07 | 0 | 0 | Amine-grafting; Blocking N-2 adsorption sites; CO2 active sites; CO 2 capture; Metal-organic frameworks | POST-SYNTHETIC MODIFICATION; POROUS MATERIALS; CARBON CAPTURE; ACID; MOFS; SEPARATION; CONVERSION; CHEMISTRY; CATALYSTS; GAS | Amine-grafting; Blocking N<sub>2</sub> adsorption sites; CO<sub>2</sub> active sites; CO<sub>2</sub> capture; Metal-organic frameworks | Metal-Organic Frameworks; Active site; Adsorption site; Alkylamine; Amine-grafting; Blocking N2 adsorption site; Blockings; CO2 active site; CO2 capture; Metalorganic frameworks (MOFs); N 2 adsorption; Grafting (chemical) | English | 2025 | 2025-08-15 | 10.1016/j.fuel.2025.135143 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Oligodendrocyte Precursor Cell-Specific HMGB1 Knockout Reduces Immune Cell Infiltration and Demyelination in Experimental Autoimmune Encephalomyelitis Models | Infiltration and activation of peripheral immune cells are critical in the progression of multiple sclerosis and its experimental animal model, experimental autoimmune encephalomyelitis (EAE). This study investigates the role of high mobility group box 1 (HMGB1) in oligodendrocyte precursor cells (OPCs) in modulating pathogenic T cells infiltrating the central nervous system through the blood-brain barrier (BBB) by using OPC-specific HMGB1 knockout (KO) mice. We found that HMGB1 released from OPCs promotes BBB disruption, subsequently allowing increased immune cell infiltration. The migration of CD4+ T cells isolated from EAE-induced mice was enhanced when co-cultured with OPCs compared to oligodendrocytes (OLs). OPC-specific HMGB1 KO mice exhibited lower BBB permeability and reduced immune cell infiltration into the CNS, leading to less damage to the myelin sheath and mitigated EAE progression. CD4+ T cell migration was also reduced when co-cultured with HMGB1 knock-out OPCs. Our findings reveal that HMGB1 secretion from OPCs is crucial for regulating immune cell infiltration and provides insights into the immunomodulatory function of OPCs in autoimmune diseases. © Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences 2025. | Kim, Gyuree; Seo, JiHye; Kim, Bokyung; Park, Young-Ho; Lee, Hong Jun; Guo, Fuzheng; Lee, Dong-Seok | BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, South Korea, School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, 41566, South Korea; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, South Korea, School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, 41566, South Korea; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, South Korea, School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, 41566, South Korea, Illimis Therapeutics, Inc., Seoul, 06376, South Korea; Futuristic Animal Resource & Research Center (FARRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, 28116, South Korea; College of Medicine and Medical Research Institute, Chungbuk National University, Chungbuk, Cheongju, 28644, South Korea, Research Institute, huMetaCELL Inc., 220 Bugwang-ro, Gyeonggi-do, Bucheon-si, 14786, South Korea; Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children Northern California, Sacramento, 95817, CA, United States, Department of Neurology, School of Medicine, University of California, Davis, Davis, 95817, CA, United States; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, South Korea, School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, 41566, South Korea | 59701746500; 59701922500; 57205869587; 56246852400; 35215736300; 55417301800; 57210068061 | lee1@knu.ac.kr; | Neuroscience Bulletin | NEUROSCI BULL | 1673-7067 | 1995-8218 | SCIE | NEUROSCIENCES | 2024 | 5.8 | 12.3 | 0 | 2025-05-07 | 0 | Experimental autoimmune encephalomyelitis; High mobility group box 1; Multiple sclerosis; Oligodendrocyte precursor cell | English | Article in press | 2025 | 10.1007/s12264-025-01381-9 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Room-temperature oxidative desulfurization with tungsten oxide supported on NU-1000 metal-organic framework | A homogeneously dispersed and immobilized tungsten oxide (WO3) catalyst supported on a metal-organic framework (MOF) NU-1000 was prepared for the first time and applied for the oxidation of organic sulfur compounds (OSCs) from liquid fuels. The composite was prepared at room temperature; therefore, cost-effective and environmentally friendly. The defective sites of NU-1000 helped the firm immobilization of WO3 species within the NU-1000 pores. The composite material denoted as W@NU-1000 was prepared from ammonium tungstate para pentahydrate in the presence of NU-1000 using nitric acid as a precipitating agent. The material was characterized by several techniques including XRD, FTIR, TGA, N2 adsorption-desorption, XPS, SEM, and TEM. The material showed remarkable performances in the oxidative conversion of dibenzothiophene (DBT, a typical OSC) using H2O2 as an oxidant. For example, almost complete conversion of DBT (1000 ppm) was achieved at room temperature within 120 min of the reaction, and the activation energy was very low of 25.9 kJmol- 1. The remarkable performance of the catalyst might be due to the well-dispersed WO3 (that can effectively activate H2O2) and relatively high porosity. The radical scavenger experiments and electron spin resonance analyses confirmed a non-radical pathway for the oxidation of DBT probably by the formation of a W6+-peroxo complex during the oxidation process. The material W@NU-1000 could be used for five cycles without any loss in performance, suggesting that it can be utilized as a potential oxidation catalyst. | Ahmed, Imteaz; Jhung, Sung Hwa | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea | Jhung, Sung/AAO-6683-2021 | 55377179600; 6701659467 | imteaz2004@gmail.com; sung@knu.ac.kr; | FUEL | FUEL | 0016-2361 | 1873-7153 | 393 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 7.5 | 12.3 | 2.53 | 2025-05-07 | 2 | 2 | MOF composites; NU-1000; Oxidative desulfurization; Room temperature oxidation; Tungsten oxide | HIGHLY-ACTIVE CATALYST; DIESEL FUEL; CARBON; DENITROGENATION; OIL | MOF composites; NU-1000; Oxidative desulfurization; Room temperature oxidation; Tungsten oxide | Desulfurization; Hafnium compounds; Indium phosphide; Nitric acid; Dibenzothiophenes; Metalorganic frameworks (MOFs); Metal–organic framework composite; NU-1000; Organic sulfur compounds; Oxidative desulfurization; Performance; Room temperature oxidation; Tungsten oxide; ]+ catalyst; Electron spin resonance spectroscopy | English | 2025 | 2025-08-01 | 10.1016/j.fuel.2025.135043 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Selective enrichment of electrode-associated cells enhances CO2 conversion to acetate in microbial electrosynthesis cells | Microbial Electrosynthesis (MES) converts CO2 into valuable products (e.g., acetate, volatile fatty acids, and CH4) through electron transfer facilitated by electroactive bacteria. Both electrode-attached and suspended cells can obtain reducing power from electron donors such as electrode and by-products (e.g., H2, formate) in MES. This study compared the performance of electrode-attached and suspended cells for acetate production. Potential application and periodic medium replacement at different rates were applied to enrich electrode-attached cells selectively. H2 and formate were each used as electron donors for suspended cells, and the addition amounts were pre-adjusted to ensure a constant cycle. As a result, the electrode-attached cells with 100% medium replacement achieved the highest acetate production (0.50 f 0.02 g/L/day) and Coulombic efficiency (86 f 3.4%), whereas 50% medium replacement with both electrode-attached and suspended cells was slightly lower (0.36 f 0.01 g/L/day, 77 f 2.1%). The formate-augmented and H2-augmented MES produced only 0.29 f 0.01 and 0.17 f 0.01 g/L/day of acetate, respectively. Field emission scanning electron microscopy revealed an aggregated electrode-attached biofilm and mediators supporting direct electron transfer. In separated cultures in serum bottles, electrode-attached cells showed higher protein content and specific acetate production rate, which were higher than those of suspended cells. A comparison of the performance of electrode-attached/suspended cells through selective enrichment suggested that the electron transfer of electrode-attached cells can improve the CO2 conversion and efficiency of MES. | Yoo, Jiin; Kim, Minsoo; Kim, Eunseo; Song, Young Eun; Maile, Nagesh; Son, Sang Hwan; Kim, Hyoung-il; Kim, Soo Rin; Kim, Jung Rae | Pusan Natl Univ, Sch Chem Engn, Busan 46241, South Korea; Lawrence Berkeley Natl Lab, Adv Biofuel & Bioprod Proc Dev Unit, Emeryville, CA 94608 USA; Yonsei Univ, Sch Civil & Environm Engn, Seoul 03722, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Pusan Natl Univ, Inst Environm Energy, Busan 46241, South Korea | Kim, Hyoung-il/D-1053-2014; Song, Young Eun/ACM-4654-2022 | 59009101500; 58758520700; 58899219500; 56609495900; 57193804539; 59931601400; 57211720610; 36659584200; 8545413900 | j.kim@pusan.ac.kr; | FUEL | FUEL | 0016-2361 | 1873-7153 | 401 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 7.5 | 12.3 | 0 | 2025-06-11 | 0 | 0 | Microbial electrosynthesis; Acetate production; Electron transfer; Electrode-attached cell | GEN. NOV. | Acetate production; Electrode-attached cell; Electron transfer; Microbial electrosynthesis | Electropolymerization; Acetate production; CH 4; Electrode-attached cell; Electron donors; Electron transfer; Microbial electrosynthesis; Microbials; Performance; Selective enrichment; Suspended cells; Microbial electrodes | English | 2025 | 2025-12-01 | 10.1016/j.fuel.2025.135832 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Strategic conversion of industrial plastic waste into transportation fuel using iron and strontium containing metal waste as a catalyst | Metal waste (MW) produced from different manufacturing companies has been considered a hazardous material and discarded in secured landfilling sites. The complicated chemical composition of MW made it difficult to be used as a beneficial material. When the hazardous waste is reused as a useful material, waste recycling with the minimization of hazardous waste landfilling could be achieved. In this study, MW from magnetic materials producing from facilities was utilized as a catalyst for conversion of polyethylene based industrial plastic waste (IPW) into more valuable transportation fuel. Without MW catalyst, IPW was converted into long chained HCs at 600 & ring;C. Multi-zone pyrolysis further degraded them into shorter ones (average carbon length: C17), but the carbon chain length was still higher than those of diesel and aviation fuels. MW catalyst enhanced the C-C and C-H bond scissions, producing C7-16 HCs and H2 as major components. The catalytic activity was attributed to the presence of transition and alkaline (earth) metal (oxide) such as Iron (oxide), Strontium (oxide), and their alloys in MW. IPW plastic oil from catalytic pyrolysis (C13.22H25.86 for 45.99 MJ kg-1) had similar chemical formula and heating value of petrodiesel (C12.3H22.2 for 42.5 MJ kg-1) and jet fuel (C10.17H19.91 for 43.23 MJ kg- 1). Therefore, this study demonstrated that the hazardous MW from industry could be employed as a catalyst for conversion of low-quality plastic oil into higher quality transportation fuel. | Jeong, Huijeong; Lee, Sangyoon; Kwon, Eilhann E.; Jung, Sungyup | Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Hanyang Univ, Dept Earth Resources & Environm Engn, Seoul 04763, South Korea | Kwon, Eilhann/AGY-3339-2022; Jung, Sungyup/GZG-6207-2022 | 59253143300; 57214885455; 9240622100; 55073290800 | ek2148@hanyang.ac.kr; sjung001@knu.ac.kr; | FUEL | FUEL | 0016-2361 | 1873-7153 | 394 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 7.5 | 12.3 | 0 | 2025-05-07 | 0 | 0 | Pyrolysis; Plastic; Hazardous metal waste; Secured landfill; Transportation fuel | HYDROGEN-RICH GAS; PYROLYSIS; HEAT; GASIFICATION; BIOMASS; STEAM; COAL; NI | Hazardous metal waste; Plastic; Pyrolysis; Secured landfill; Transportation fuel | Jet fuel; Pyrolysis; Strontium compounds; Chemical compositions; Hazardous metal waste; Hazardous metals; Landfilling; Manufacturing companies; Plastics waste; Secured landfill; Transportation fuels; Waste catalysts; ]+ catalyst; Strontium alloys | English | 2025 | 2025-08-15 | 10.1016/j.fuel.2025.135127 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A Pharmacokinetic/Pharmacodynamic Study of Esomeprazole Comparing a Dual Delayed-Release Formulation (YYD601) to a Conventional Formulation Following Multiple Administrations in Healthy Adult Subjects | Background: YYD601 is a new dual delayed-release formulation of esomeprazole, developed to enhance plasma exposure and prolong the duration of acid suppression. Purpose: This study aimed to evaluate the safety, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of YYD601 20 mg following single and multiple oral administrations in healthy, fasting adult Koreans, and to compare these outcomes to those of the conventional esomeprazole 20 mg capsule. Methods: A randomized, open-label, two-period crossover study was conducted in 28 participants, who were divided into two treatment groups: one group received YYD601 20 mg, and the other received conventional esomeprazole 20 mg, once daily for five consecutive days. Blood samples for PK analysis were collected pre-dose and up to 24 hours post-dose. The primary PK parameters (AUC(last) and AUC(tau)) were evaluated. PD endpoints included integrated gastric acidity, percentage of time with intragastric pH > 4 over 24-hour and nighttime intervals, and percent change in serum gastrin levels after multiple dosing. Results: A total of 22 participants completed the study. YYD601 displayed more prolonged plasma concentration-time profiles than the conventional formulation, although the extent of the systemic exposure (AUC values) showed no statistically significant difference between the two formulations. With regard to the 24-hour gastric acid inhibition, YYD601 was comparable to the conventional formulation. The YYD601 showed a greater tendency for acid inhibition at night, as indicated by the percentage change of time with nocturnal acid breakthrough and other PD parameters. Both treatments were well tolerated, with no serious adverse events reported. Conclusion: Through extended systemic exposure of esomeprazole, YYD601 produces gastric acid suppression that is comparable to that of the conventional esomeprazole formulation, with a greater tendency to suppress acid at night. YYD601 20 mg was safe and well tolerated following single and multiple oral administrations, supporting its use as an effective alternative to conventional esomeprazole therapy. Clinical Trial Registry: http://clinicaltrials.gov, NCT03985319 (Date of registration: May 29, 2019; Study period: between July 2019 and March 2020). | Lee, Hae Won; Kang, Woo Youl; Park, Ji Seo; Lee, Jae Hwa; Park, Jin Ju; Gwon, Mi-Ri; Yoon, Young-Ran; Seong, Sook Jin | Kyungpook Natl Univ, Sch Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Clin Pharmacol & Therapeut, 130 Dongdeok Ro, Daegu 41944, South Korea; Natl Inst Food & Drug Safety Evaluat, Innovat Prod Support Dept, Clin Trial Dossier Evaluat Team, Cheongju 28159, South Korea | Park, Jin Ju/AAE-7556-2022; Yoon, Young-Ran/GLT-0172-2022 | 57202973823; 56816263900; 58164580000; 58165025100; 59518524800; 56035800800; 14629744500; 57211130049 | yry@knu.ac.kr; wintersj@knu.ac.kr; | DRUG DESIGN DEVELOPMENT AND THERAPY | DRUG DES DEV THER | 1177-8881 | 19 | SCIE | CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY | 2024 | 5.1 | 12.4 | 0 | 2025-05-07 | 0 | 1 | esomeprazole; dual delayed-release formulation; pharmacokinetics; pharmacodynamics | 40 MG; ACID CONTROL; PHARMACODYNAMICS; PHARMACOKINETICS; PH; LANSOPRAZOLE; RABEPRAZOLE; OMEPRAZOLE; DEXLANSOPRAZOLE; PANTOPRAZOLE | dual delayed-release formulation; esomeprazole; pharmacodynamics; pharmacokinetics | Administration, Oral; Adult; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Esomeprazole; Female; Healthy Volunteers; Humans; Male; Middle Aged; Proton Pump Inhibitors; Young Adult; alanine aminotransferase; aspartate aminotransferase; bilirubin; chemical compound; esomeprazole; gastrin; unclassified drug; yyd601; esomeprazole; proton pump inhibitor; accuracy; adult; Article; blood pressure; blood sampling; body temperature; controlled study; crossover procedure; delayed release formulation; drug formulation; drug safety; dual delayed release formulation; electrocardiogram; gastric pH monitoring; heart rate; human; human experiment; limit of quantitation; liquid chromatography-mass spectrometry; male; maximum concentration; multiple reaction monitoring; normal human; open study; pharmacodynamics; pharmacokinetic parameters; pharmacokinetics; phase 1 clinical trial; precipitation; randomized controlled trial; stomach pH; urinalysis; comparative study; crossover procedure; dose response; female; middle aged; normal human; oral drug administration; young adult | English | 2025 | 2025 | 10.2147/dddt.s500253 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Administration route-dependent pharmacokinetic and biopharmaceutical features of steppogenin | Purpose: This study aimed to develop liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for steppogenin and to assess its bioavailability (BA) and biopharmaceutical features in mice when administered via different route. Methods: The LC-MS/MS method for steppogenin was validated and used to investigate the pharmacokinetics of steppogenin in mice. A calibration curve was prepared in the range of 1–1,000 ng/mL of calibration standards and three levels of quality control samples (3, 125, and 750 ng/mL). Thereafter, the pharmacokinetics and BA of steppogenin were investigated following its administration via four different routes (i.e., intravenous [IV], subcutaneous [SC], intraperitoneal [IP], and per oral [PO]). Results: The linearity, inter- and intra-day precision, accuracy, and stability results were within 15% of the coefficient of variance (CV, %). Mean recoveries and the matrix effect of steppogenin were 68.06–89.47% and 59.03–66.72% with less than 11.87% and 9.031% of CV, respectively. BA of steppogenin administered via IV, SC, IP, and PO was determined as 100%, 84.7–96.0%, 54.0–54.6%, and 5.73–10.0%, respectively. P-glycoprotein (P-gp) efflux and first-pass phase II metabolism could have led to the low PO and moderate IP BA of steppogenin. The co-administration of a P-gp inhibitor (i.e., verapamil or D-α-tocopherol polyethylene glycol 1000 succinate) significantly increased the oral BA of steppogenin by 315% and 149%, respectively. Conclusion: The favorable pharmacokinetic features of steppogenin administered as IV or SC injection could result in its better therapeutic efficacy than when administered IP or PO. To improve oral BA, formulation strategies could incorporate inhibitors of P-gp-mediated efflux and first-pass metabolism. © The Author(s) under exclusive licence to The Korean Society of Pharmaceutical Sciences and Technology 2025. | Lee, Jihoon; Pang, Minyeong; Jeon, So Yeon; Kim, Yoon Gyoon; Lee, You Mie; Choi, Min-Koo; Song, Im-Sook | BK21 FOUR Community‑Based Intelligent Novel Drug Discovery Education Unit, Vessel‑Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; College of Pharmacy, Dankook University, Cheon‑an, 31116, South Korea; College of Pharmacy, Dankook University, Cheon‑an, 31116, South Korea; College of Pharmacy, Dankook University, Cheon‑an, 31116, South Korea; BK21 FOUR Community‑Based Intelligent Novel Drug Discovery Education Unit, Vessel‑Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; College of Pharmacy, Dankook University, Cheon‑an, 31116, South Korea; BK21 FOUR Community‑Based Intelligent Novel Drug Discovery Education Unit, Vessel‑Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, 92697, United States | 57195979045; 57488599500; 57226815842; 36062983500; 8230508600; 8695781400; 7201564500 | isssong@knu.ac.kr; minkoochoi@dankook.ac.kr; | Journal of Pharmaceutical Investigation | J PHARM INVEST | 2093-5552 | 2093-6214 | SCIE | PHARMACOLOGY & PHARMACY | 2024 | 5.1 | 12.4 | 7.7 | 2025-05-07 | 2 | Bioavailability (BA); Liquid chromatography-tandem mass spectrometry; P-glycoprotein (P-gp); Pharmacokinetics; Steppogenin | English | Article in press | 2025 | 10.1007/s40005-025-00730-0 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Increased lamina propria B cells play roles in fructose-induced hypertension of Dahl salt-sensitive rats | Aims: Although the immune system participates in the development of hypertension, the proportional contributions of distinct immune cells remain poorly understood. With the development of transcriptomics, we can profile the transcriptomes of individual immune cells and assess the relative contribution of each immune cell to the development of hypertension. So, we tested the hypothesis that increased lamina propria B cells play roles in fructose-induced hypertension of Dahl salt-sensitive (SS) rats. Materials and methods: Eight-week-old Dahl SS and Dahl salt-resistant (SR) male rats were divided into four groups; each group received either tap water (TW) or a 20 % fructose solution (HFS) for 4 weeks. Systolic blood pressure was measured using the tail-cuff method. Single-cell RNA sequencing (scRNA-seq) analysis was performed on lamina propria (LP) cells and peripheral blood mononuclear cells (PBMCs) obtained from the SS and SR rats subjected to either TW or HFS. Key findings: Results revealed that high-fructose intake induced hypertension in the SS rats but not in the SR rats. It also increased B cells in LPs but not in PBMCs of the SS rats; their subsets showed increased follicular and na & iuml;ve B cells. Increased lamina propria B cells play roles in fructose-induced hypertension of SS rats. Significance: This finding suggest that targeting B cells could be a potential strategy to mitigate high blood pressure in fructose-induced hypertension. | Jang, Sungmin; Kim, Cheong-Wun; Olarinoye, Zainab Yetunde; Akter, Sadia; Kim, Inkyeom | Kyungpook Natl Univ, Sch Med, Dept Pharmacol, 680 Gukchaebosang St, Daegu 41944, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, BK21 Plus KNU Biomed Convergence Program, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, Daegu 41944, South Korea | 57897824500; 56662531400; 58925215900; 59472655700; 7404144630 | inkim@knu.ac.kr; | LIFE SCIENCES | LIFE SCI | 0024-3205 | 1879-0631 | 361 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2024 | 5.1 | 12.4 | 0 | 2025-05-07 | 0 | 0 | Fructose-induced hypertension; Dahl-salt resistant rat; Dahl-salt sensitive rat; Single-cell RNA sequencing; B cell; Monocyte | NITRIC-OXIDE; ANGIOTENSIN; ALDOSTERONE | B cell; Dahl-salt resistant rat; Dahl-salt sensitive rat; Fructose-induced hypertension; Monocyte; Single-cell RNA sequencing | Animals; B-Lymphocytes; Blood Pressure; Fructose; Hypertension; Male; Mucous Membrane; Rats; Rats, Inbred Dahl; ADP ribosyl cyclase/cyclic ADP ribose hydrolase 1; B7 antigen; CD14 antigen; CD27 antigen; CD9 antigen; cytokine receptor; fructose; interleukin 10; pentobarbital; fructose; animal experiment; animal model; animal tissue; Article; B lymphocyte; B lymphocyte activation; blood clotting; cell differentiation; cell population; Dahl salt resistant rat; Dahl salt sensitive rat; dephosphorylation; down regulation; erythrocyte; gene expression; gene ontology; hypertension; inflammatory bowel disease; lamina propria; monocyte; NF kB signaling; nonhuman; peripheral blood mononuclear cell; principal component analysis; rat; single cell RNA seq; systolic blood pressure; T lymphocyte; Th1 cell; Th17 cell; thrombocyte; TNF signaling; trypanosomiasis; upregulation; wound healing; animal; blood pressure; Dahl rat; drug effect; immunology; male; metabolism; mucosa; pathology | English | 2025 | 2025-01-15 | 10.1016/j.lfs.2024.123314 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Oral bioavailability enhancement of chrysin using a spray-dried solid dispersion formulation with sodium dodecyl sulfate and polyvinylpyrrolidone | Purpose: Chrysin has many pharmacological activities but suffers from low bioavailability (BA) due to its poor solubility and intestinal first-pass effect. This study aimed to develop a chrysin formulation that enhances its BA by inhibiting intestinal metabolism and increasing solubility. Methods: A solid dispersion of chrysin (chrysin-SD) was prepared using the spray-drying method and characterized for solubility, metabolic inhibition, and pharmacokinetic properties of chrysin-SD in rats. Results: Sodium dodecyl sulfate (SDS) and polyvinylpyrrolidone (PVP) were selected as solubility-enhancing surfactants as well as inhibitors of chrysin glucuronidation and hydrophilic carriers, respectively. The optimized formulation had a chrysin: SDS: PVP ratio of 1:5:3 (w/w/w). Chrysin-SD increased chrysin solubility by 848-fold and the dissolution rate to 72.3% of the initial amount, compared to 3.11% for pure chrysin. This improvement was attributed to SDS, PVP, and the amorphous nature of chrysin-SD. Additionally, chrysin-SD increased absorptive permeability in the duodenum, jejunum, and ileum by 2.99- to 7.33-fold in rat models, without affecting secretory permeability. Chrysin-SD also suppressed the formation of chrysin glucuronide (chrysin-G), suggesting enhanced intestinal absorption through increased intestinal permeability and decreased intestinal glucuronidation. These findings were confirmed by a 19.7-fold increase in chrysin’s area under the curve (AUC) and a 93% reduction in the chrysin-G metabolic ratio compared to the pure chrysin group. Conclusion: The chrysin-SD formulation with a chrysin: SDS: PVP ratio of 1:5:3 (w/w/w) significantly enhanced chrysin’s BA. This strategy, which improves solubility, dissolution, and intestinal absorption while reducing metabolism, offers a promising approach for enhancing the oral BA of herbal medicines like chrysin. © The Author(s) under exclusive licence to The Korean Society of Pharmaceutical Sciences and Technology 2025. | Pang, Minyoung; Lee, Jihoon; Lee, Jong-Geon; Jeon, Ji-Hyeon; Choi, Min-Koo; Song, Im-Sook | College of Pharmacy, Dankook University, Cheon-an, 31116, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Vessel, Daegu, 41566, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Vessel, Daegu, 41566, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Vessel, Daegu, 41566, South Korea; College of Pharmacy, Dankook University, Cheon-an, 31116, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Vessel, Daegu, 41566, South Korea, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, 92697, CA, United States | 59904130800; 57195979045; 57704944800; 57204685946; 8695781400; 7201564500 | minkoochoi@dankook.ac.kr; isssong@knu.ac.kr; | Journal of Pharmaceutical Investigation | J PHARM INVEST | 2093-5552 | 2093-6214 | SCIE | PHARMACOLOGY & PHARMACY | 2024 | 5.1 | 12.4 | 0 | 2025-06-11 | 0 | Chrysin; Intestinal metabolism; Oral bioavailability (BA); Solid dispersion; Solubility | English | Article in press | 2025 | 10.1007/s40005-025-00744-8 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | Article | Pharmacokinetics and tissue distribution of NXC736, a novel modulator for sphingosine-1 phosphate receptor 1 and 4, in rats | Purpose: NXC736, a novel compound that acts on sphingosine-1-phosphate (S1P) receptor 1 and 4, can treat autoimmune disease. We aimed to develop and validate the analytical method for NXC736 and its active metabolite NXC736-phosphate and to assess their pharmacokinetics and tissue distribution in rats. Methods: We conducted animal studies to evaluate the oral absorption, distribution, excretion, and toxicokinetics of NXC736 and NXC736-phosphate in rats. Results: NXC736 is converted to NXC736-phosphate via sphingosine kinase pre-systemically and in the body after absorption. NXC736 exhibited rapid absorption and high hepatic clearance and was eliminated with half-life of 3–5 h. Dose normalized plasma exposure of NXC736 showed dose dependency in an oral dose range of 3–30 mg/kg and became saturated in the dose range of 37.5–150 mg/kg. Subsequently, the NXC736-phosphate conversion rate was decreased dose-dependently, suggesting sphingosine kinase saturation. After the repeated oral administration of NXC736 (37.5–150 mg/kg) for 28 days, NXC736-phosphate accumulation was less than 2-fold, and no toxicity was observed in any rat. Blood lymphocyte inhibition, a pharmacological marker for NXC736, occurred by approximately 35%, 53%, and 56% at NXC736 doses of 37.5, 75, and 150 mg/kg/day, respectively, but recovered in a few days to control levels, suggesting NXC736 exhibits reversible activity. Conclusion: These findings provided crucial insights into the pharmacokinetic profiles of NXC736 and NXC736-phosphate, including absorption, distribution, metabolism, and excretion, and can help bridge research into human studies and in planning and interpreting clinical trials. © The Author(s) under exclusive licence to The Korean Society of Pharmaceutical Sciences and Technology 2025. | Kim, Eun Jeong; Park, Yang Hea; Lee, Bong Yong; Song, Im-Sook; Lee, Hye Suk | NextGen Bioscience Inc., Pangyo, 13487, South Korea, Drug Metabolism & Bioanalysis Laboratory, College of Pharmacy, The Catholic University of Korea, Bucheon, 14662, South Korea; NextGen Bioscience Inc., Pangyo, 13487, South Korea; NextGen Bioscience Inc., Pangyo, 13487, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; Drug Metabolism & Bioanalysis Laboratory, College of Pharmacy, The Catholic University of Korea, Bucheon, 14662, South Korea | 59512329900; 59949783500; 57432013300; 7201564500; 59734585600 | sianalee@catholic.ac.kr; | Journal of Pharmaceutical Investigation | J PHARM INVEST | 2093-5552 | 2093-6214 | SCIE | PHARMACOLOGY & PHARMACY | 2024 | 5.1 | 12.4 | N/A | 0 | Lymphocyte counting; NXC736; NXC736-phosphate; Pharmacokinetics; S1PR modulator; Tissue distribution | English | Article in press | 2025 | 10.1007/s40005-025-00747-5 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | EAEFA-R: Multiple learning-based ensemble artificial electric field algorithm for global optimization | Adjusting the search behaviors of swarm-based algorithms is crucial for solving real-world optimization challenges. Researchers have developed ensemble strategies and self-adaptive mechanisms to enhance the optimization ability of individual algorithms by balancing global and local search capabilities. Inspired by these advancements, this paper proposes a physics-based artificial electric field algorithm with three improvement strategies and an attraction-repulsion operator (EAEFA-R) to enhance diversity and escape local optima. These strategies are probabilistically selected using a dynamic adaptation mechanism. The effectiveness of EAEFA-R is assessed through extensive analysis of exploration-exploitation dynamics and diversity, and it is evaluated on two real-parameter test suites, CEC 2017 and CEC 2022, across 10, 20, 30, 50, and 100-dimensional search spaces. Compared to fifteen state-of-the-art algorithms, including AEFA variants and other optimization algorithms, EAEFA-R demonstrates superior solution accuracy, convergence rate, search capability, and stability performance. The overall ranking highlights its exceptional potential for solving challenging optimization problems, outperforming other state-of-the-art algorithms across various dimensions. The MATLAB source code of EAEFA-R is available at https://github.com/ChauhanDikshit. | Chauhan, Dikshit; Yadav, Anupam; Mallipeddi, Rammohan | Dr BR Ambedkar Natl Inst Technol Jalandhar, Dept Math & Comp, Jalandhar 144008, Punjab, India; Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea | Chauhan, Dikshit/JUF-5726-2023; Yadav, Dr Anupam/Y-1063-2019; Mallipeddi, Rammohan/AAL-5306-2020 | 57656655600; 55220521500; 25639919900 | dikshitchauhan608@gmail.com; anupam@nitj.ac.in; mallipeddi.ram@gmail.com; | KNOWLEDGE-BASED SYSTEMS | KNOWL-BASED SYST | 0950-7051 | 1872-7409 | 318 | SCIE | COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE | 2024 | 7.6 | 12.5 | 0 | 2025-05-07 | 0 | 0 | Meta-heuristic algorithms; Optimization; Ensembling; Repulsion strategy; Artificial electric field algorithm | POWER | Artificial electric field algorithm; Ensembling; Meta-heuristic algorithms; Optimization; Repulsion strategy | Heuristic algorithms; Artificial electric field algorithm; Ensembling; Global optimisation; Meta-heuristics algorithms; Optimisations; Real-world optimization; Repulsion strategy; Search behavior; Search capabilities; State-of-the-art algorithms; Optimization algorithms | English | 2025 | 2025-06-07 | 10.1016/j.knosys.2025.113453 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | Efficacy of Remimazolam in Anesthetic Induction: Population Characteristic Concerns-In Response | Lee, Sou-Hyun; Kim, Kyungmi | Kyungpook Natl Univ, Med Ctr, Sch Med, Dept Anesthesiol & Pain Med, Daegu, South Korea; Korea Univ, Coll Med, Anam Hosp, Dept Anesthesiol & Pain Med, Seoul, South Korea | 57223957892; 57200729870 | kyungmi_kim@korea.ac.kr; | ANESTHESIA AND ANALGESIA | ANESTH ANALG | 0003-2999 | 1526-7598 | 141 | 1 | SCIE | ANESTHESIOLOGY | 2024 | 3.8 | 12.5 | 0 | 2025-06-11 | 0 | 0 | ephedrine; noradrenalin; remifentanil; remimazolam; adverse outcome; coronary artery bypass graft; diseases; elective surgery; endotracheal intubation; heart surgery; hemodynamics; human; hypotension; Letter; mean arterial pressure; article | English | 2025 | 2025-07 | 10.1213/ane.0000000000007544 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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