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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article A 20-W Wide Bandwidth GaN HEMT Power Amplifier for VHF/UHF Applications In this article, broadband gallium nitride (GaN) high-electron-mobility transistor (HEMT) power amplifier with shunt-feedback and push-pull technique is presented. Shunt-feedback and push-pull realization provide the robust broad bandwidth covering very high frequency and low-frequency ultra high frequency (UHF) bands. The benefit due to the feedback presented in the form of shunt-shunt network on power amplifier module provides the linear and broadband frequency amplification. The push-pull topology provides enhanced efficiency and high power generation along with the cancellation of the second-order distortions and thus helps to compensate for the efficiency degradation from the feedback. These techniques are realized with the help of in-house designed GaN HEMT transistor, which provides high power, good efficiency, and high reliability (bandgap). The prototype was realized in 0.25-mu m GaN HEMT, operates from 30 to 520 MHz, and dissipates 650 mA of quiescent current from 28-V supply. The power amplifier delivered a saturated output power of >43 dBm and 40% power added efficiency at 20 W output power. The linearity of the amplifier was characterized by the two-tone injection test. The measurement result shows that the third-order intermodulation distortion tones are below -35 dBc at 35 dBm output power. Kim, Jusung; Kim, Younghoon; Oh, Seongwon; Choi, Jaehyung; Lee, Dong-Ho; Cho, Kunhee; Lee, Sanghun; Ahn, Chi-Hyung Hanbat Natl Univ, Dept Elect & Control Engn, Daejeon 34158, South Korea; Wavepia Incorp, Hwaseong Si 18469, South Korea; Mokpo Natl Maritime Univ, Div Naval Officer Sci, Mokpo 58628, South Korea; Hanbat Natl Univ, Dept Informat & Commun Engn, Daejeon 34158, South Korea; Qualcomm Technol Inc, Santa Clara, CA 95051 USA; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Korea Univ Technol & Educ, Cheonan 31253, South Korea jusungkim@hanbat.ac.kr;yhkim@wavepia.com;osw123@mmu.ac.kr;jepiros2513@naver.com;dhlee@hanbat.ac.kr;khcho128@gmail.com;platune@wavepia.com;chahn@koreatech.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 67 12 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2020 8.236 2.3 14 Gallium nitride; Bandwidth; Gain; Power generation; Radio frequency; HEMTs; Power amplifiers; Broadband; feedback; gallium nitride (GaN); high-electron-mobility transistor (HEMT); push-pull DESIGN; DISTORTION English 2020 2020-12 10.1109/tie.2019.2960749 바로가기 바로가기 바로가기
Article A Reliable Single-Phase Bipolar Buck-Boost Direct PWM AC-AC Converter With Continuous Input/Output Currents In this article, a single-phase bipolar buck-boost direct pulsewidth-modulated ac-ac converter is proposed, comprised of six insulated-gate bipolar transistors, a small film capacitor, and input/output LC filters. The converter can provide discrete noninverting buck (NIBu) and boost (NIBo) operations with voltage gains of D and 1/(1 - D), respectively. Moreover, it provides symmetric noninverting buck-boost (NIBB) and inverting buck-boost (IBB) operations with voltage gains of D/(1 - D) and -D/(1 - D), respectively. It supplies both continuous input/output currents, and it is well suited for reactive loads. It is immune from the commutation problem, and thus, has enhanced the reliability. The various modes of operation of the proposed converter make it suitable for diverse applications, including the following: 1) application as a direct ac voltage regulator when operating in NIBu and NIBo modes; 2) IBB operation can be utilized along with NIBu/ NIBo or NIBB operation to compensate both voltage sag and swell, when used as dynamic voltage restorer; and 3) symmetric NIBB/IBB operations can provide step-changed frequency output, similar to the single-phase matrix converters, for applications as induction motor drive or high-gain ac-dc rectifier. Extensive circuit analysis, component design guidelines, and appropriate comparisons are provided, followed by experimental results obtained using a laboratory prototype. Ahmed, Hafiz Furqan; El Moursi, Mohamed Shawky; Cha, Honnyong; Al Hosani, Khalifa; Zahawi, Bashar Khalifa Univ, Dept Elect Engn & Comp Sci, Abu Dhabi 127788, U Arab Emirates; Mansoura Univ, Fac Engn, Mansoura 35516, Egypt; Kyungpook Natl Univ, Sch Energy Engn, Daegu 1370, South Korea Ahmed, Hafiz/GWR-3787-2022; Moursi, Mohamed/F-2942-2013 56735445800; 21739149200; 24450248400; 35301818900; 7003814281 hafiz.ahmed@ku.ac.ae;mohamed.elmoursi@ku.ac.ae;chahonny@knu.ac.kr;khalifa.halhosani@ku.ac.ae;bashar.zahawi@ku.ac.ae; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 67 12 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2020 8.236 2.3 1.22 2025-06-25 25 32 AC-AC converters; Inductors; Capacitors; Voltage control; Switches; Pulse width modulation; Voltage fluctuations; AC-AC converter; bipolar output voltage; buck-boost operation; commutation problem; voltage sag; swell DYNAMIC VOLTAGE RESTORER; MATRIX CONVERTER; TRANSFORMER; CONDITIONER AC-AC converter; bipolar output voltage; buck-boost operation; commutation problem; voltage sag/swell Electric inverters; Electric rectifiers; Gain measurement; Induction motors; Matrix converters; Pulse width modulation; Rectifying circuits; Voltage regulators; Ac voltage regulators; Commutation problem; Diverse applications; Dynamic voltage restorer (DVR); Induction motor drive; Modes of operation; Pulse-width-modulated; Single phase matrix converter; DC-DC converters English 2020 2020-12 10.1109/tie.2019.2958290 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Eletrocardiographic Changes as a Prognostic Tool for Hospitalized Patients with Pulmonary Embolism Cha, S.; Park, J.; Park, S.; Choi, S. Kyungpook Natl Univ Hosp, Div Pulm & Crit Care Med, Daegu, South Korea AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE AM J RESP CRIT CARE 1073-449X 1535-4970 201 SCIE CRITICAL CARE MEDICINE;RESPIRATORY SYSTEM 2020 21.405 2.3 0 English 2020 2020 바로가기 바로가기
Article Highly reliable quinone-based cathodes and cellulose nanofiber separators: toward eco-friendly organic lithium batteries Abstract: Recently, organic compounds are considered as promising candidates for application in next-generation energy storage systems to overcome the disadvantages of conventional inorganic cathode materials, including their low specific capacity and poor disposal systems. In particular, pillar[5]quinone (P5Q) is very effective as it provides active sites that favor Li uptake and promote a high theoretical capacity. Herein, we propose P5Q-derived cathodes, which are enveloped in multi-walled carbon nanotubes and cellulose nanofibers (CNFs), fabricated by a simple vacuum-filtering method. The designed cathode solves the issues associated with organic materials, including their high solubilities in aprotic electrolytes and low conductivities. Furthermore, CNFs are introduced as alternatives to conventional polyolefin separators. CNF separators can effectively suppress the dissolution of active materials in liquid electrolytes. In addition, CNFs improve ionic conductivity (0.88 mS cm−1), electrolyte wettability (electrolyte uptake: 333.41%, porosity: 70 ± 5%), and thermal shrinkage in contrast to conventional polyolefin separators. The Li-ion battery, assembled with the suggested P5Q cathode and CNF separator, exhibits highly stable capacity retention (76.5% after 50 cycles at a 0.2 C rate) and good rate capability, although an organic electrolyte is used. Graphic abstract: [Figure not available: see fulltext.]. © 2020, Springer Nature B.V. Yoo, Gayeong; Pyo, Seonmi; Gong, Yong Jun; Cho, Jinil; Kim, Heebae; Kim, Youn Sang; Yoo, Jeeyoung Program in Nano Science and Technology, Graduate School of Convergence Science and Technology (GSCST), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; Program in Nano Science and Technology, Graduate School of Convergence Science and Technology (GSCST), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; Program in Nano Science and Technology, Graduate School of Convergence Science and Technology (GSCST), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; Program in Nano Science and Technology, Graduate School of Convergence Science and Technology (GSCST), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; Program in Nano Science and Technology, Graduate School of Convergence Science and Technology (GSCST), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; Program in Nano Science and Technology, Graduate School of Convergence Science and Technology (GSCST), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea, School of Chemical and Biological Engineering, College of Engineering, Seoul National University, Gwanak-gu, Seoul, 08826, South Korea, Advanced Institutes of Convergence Technology (AICT), 864-1 Iui-dong, Yeongtong-gu, Suwon-si, 16229, Gyeonggi-do, South Korea; School of Energy Engineering, Kyungpook National University (KNU), Daehakro 80, Bukgu, Daegu, 41566, South Korea 57204103698; 57211858131; 57203432769; 57209801309; 57217054648; 8938854200; 56046607500 younskim@snu.ac.kr;jyoo@knu.ac.kr; Cellulose CELLULOSE 0969-0239 1572-882X 27 12 SCIE MATERIALS SCIENCE, PAPER & WOOD;MATERIALS SCIENCE, TEXTILES;POLYMER SCIENCE 2020 5.044 2.3 0.68 2025-06-25 12 Carbon frame; Cellulose nanofibers; Eco-friendly LIBs; Next generation batteries; Organic lithium batteries Benzoquinone; Capacity; Cathodes; Cellulose; Electrolytes; Organic Materials; Separators; Systems; Cellulose; Cellulose nanocrystals; Electrolytes; Lithium-ion batteries; Multiwalled carbon nanotubes (MWCN); Nanocellulose; Nanofibers; Quinone; Separators; Aprotic electrolytes; Capacity retention; Cellulose nanofibers; Energy storage systems; Liquid electrolytes; Organic electrolyte; Specific capacities; Theoretical capacity; Cathodes English Final 2020 10.1007/s10570-020-03266-8 바로가기 바로가기 바로가기
Article Interturn Fault Tolerant Drive Method by Limiting Copper Loss of Interior Permanent Magnet Synchronous Motor An interturn short fault (ITF) is a common failure in electrical machines because the windings easily lose insulation characteristics due to overheating and mechanical stress. In the ITF winding, large fault current, ohmic loss, and excess winding heat are induced, resulting in fault aggravation and combustion of the machine unless adequate fault diagnosis and management are undertaken. By limiting the overall copper loss, including the component due to the ITF, the faulty motor can operate without aggravation until adequate fault management actions can be performed. In this article, an interior permanent magnet synchronous motor (IPMSM) ITF tolerant drive method by limiting internal copper loss is proposed. The copper loss by the ITF is simplified in the proposed method and analyzed for various current, speed, and output torque conditions. By maximizing the output torque with minimum IPMSM copper losses, the maximum torque per loss (MTPL) operation point is suggested. Compared to the maximum torque per ampere, the MTPL has a more efficient operation point with ITF. To verify the proposed method, experimental studies are performed with an IPMSM having ITFs. The results show the feasibility and practicality of the proposed method. Im, Seong-Hwan; Gu, Bon-Gwan Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea 57212462415; 50061273700 imsh9698@naver.com;bggu@knu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 67 9 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2020 8.236 2.3 0.64 2025-06-25 13 15 Circuit faults; Windings; Copper; Fault currents; Torque; Stator windings; Interturn short fault (ITF); fault closed circuit; maximum torque per loss (MTPL); power loss limit; ITF tolerant driving TURN FAULT; MACHINES Fault closed circuit; Interturn short fault (itf); Itf tolerant drivingg; Maximum torque per loss (mtpl); Power loss limit Copper; Electric fault currents; Failure analysis; Synchronous motors; Torque; Winding; Electrical machine; Fault diagnosis and management; Fault management; Insulation characteristics; Inter-turn fault; Interior permanent magnet synchronous motor; Maximum Torque per Ampere; Mechanical stress; Permanent magnets English 2020 2020-09 10.1109/tie.2019.2941146 바로가기 바로가기 바로가기 바로가기
Article Light-Field Camera for Fast Switching of Time-Sequential Two-Dimensional and Three-Dimensional Image Capturing at Video Rate In this article, we propose a time-sequential switching light-field (LF) camera for an alternative image capture of the high-resolution two-dimensional (2-D) images and three-dimensional (3-D) LF elemental images as additional functionalities. For image data acquisitions of both the 2-D and 3-D LF imaging of moving objects at a video frame rate (or even higher frame rate up to approximately 1000 f/s), a polarization-dependent-switching microlens array (MLA) is implemented in the LF camera system instead of a conventional passive-type MLA. By controlling the incident polarization conditions using an electrically fast-switching liquid crystal layer, the imaging mode can be time-sequentially switched quite rapidly (switching times of approximately 220 and 290 mu s for the mode conversions from the 3-D LF to the 2-D mode, and the reversal mode change, respectively). Using the elemental image sets sampled from the alternating time-sequential imaging results, either the directional-view images or depth-refocused images can be reconstructed and provided at a moving picture frame rate. The depth-refocused images are possible for a wide depth range from 25 to 350 cm. Directional views of 22 x 22 and 9 x 9 in portions can be reconstructed for the single-shot image capture and the time-sequential video-rate image capture, respectively. Joo, Kyung-Il; Park, Min-Kyu; Park, Heewon; Lee, Tae-Hyun; Kwon, Ki-Chul; Lim, Young-Tae; Erdenebat, Munkh-Uchral; Lee, Hyun; Lee, Gwangsoon; Kim, Nam; Kim, Hak-Rin Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Chungbuk Natl Univ, Sch Informat & Commun Engn, Cheongju 28644, South Korea; Elect & Telecommun Res Inst, Media Res Div, Daejeon 34128, South Korea ; Kim, Hak-Rin/T-1897-2019 36680185400; 58577884600; 57188766234; 57207924346; 7201503212; 16313591600; 36166588400; 7501489273; 7404852358; 35494120000; 7410124944 kijoo@knu.ac.kr;mkpark@knu.ac.kr;tigerph@nate.com;cylls96@naver.com;kckwon23@gmail.com;ytisco@gmail.com;uchka@osp.chungbuk.ac.kr;hlee2@etri.re.kr;gslee@etri.re.kr;namkim@chungbuk.ac.kr;rineey@knu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 67 8 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2020 8.236 2.3 0.64 2025-06-25 19 20 Three-dimensional displays; Two dimensional displays; Lenses; Cameras; Optical switches; Light-field (LF) camera; polarization-dependent microlens array (PMLA); smart camera; switchable microlens array (MLA); time-sequential image capturing for two-dimensional (2-D) and three-dimensional (3-D) LF video LIQUID-CRYSTAL LENS; ENHANCED DEPTH; ARRAY; RESOLUTION; MICROSCOPY; FREQUENCY; ACCURATE; DISPLAY; DESIGN; STEREO Light-field (LF) camera; polarization-dependent microlens array (PMLA); smart camera; switchable microlens array (MLA); time-sequential image capturing for two-dimensional (2-D) and three-dimensional (3-D) LF video Cameras; Liquid crystals; Photographic accessories; Polarization; Switching frequency; Image data acquisition; Incident polarization; Liquid crystal layers; Single-shot images; Three dimensional images; Threedimensional (3-d); Two-dimensional (2D) images; Video-rate images; Image reconstruction English 2020 2020-08 10.1109/tie.2019.2935992 바로가기 바로가기 바로가기 바로가기
Article Ocean acidification alters bacterial communities on marine plastic debris The increasing quantity of plastic waste in the ocean is providing a growing and more widespread novel habitat for microbes. Plastics have taxonomically distinct microbial communities (termed the 'Plastisphere') and can raft these unique communities over great distances. In order to understand the Plastisphere properly it will be important to work out how major ocean changes (such as warming, acidification and deoxygenation) are shaping microbial communities on waste plastics in marine environments. Here, we show that common plastic drinking bottles rapidly become colonised by novel biofilm-forming bacterial communities, and that ocean acidification greatly influences the composition of plastic biofilm assemblages. We highlight the potential implications of this community shift in a coastal community exposed to enriched CO2 conditions. Harvey, Ben P.; Kerfahi, Dorsaf; Jung, YeonGyun; Shin, Jae-Ho; Adams, Jonathan M.; Hall-Spencer, Jason M. Univ Tsukuba, Shimoda Marine Res Ctr, 5-10-1 Shimoda, Shizuoka 4150025, Japan; Keimyung Univ, Sch Nat Sci, Dept Biol Sci, Daegu 42601, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Coll Agr & Life Sci, Daegu 41566, South Korea; Nanjing Univ, Sch Geog & Oceanog Sci, Nanjing 210008, Peoples R China; Univ Plymouth, Sch Biol & Marine Sci, Plymouth PL4 8AA, Devon, England ; Hall-Spencer, Jason/AFN-7866-2022; Harvey, Ben/HGC-7584-2022 55898301900; 55893822900; 57197833801; 57224125922; 55446772900; 6603382752 ben.harvey@shimoda.tsukuba.ac.jp;jonadams@nju.ac.cn; MARINE POLLUTION BULLETIN MAR POLLUT BULL 0025-326X 1879-3363 161 SCIE ENVIRONMENTAL SCIENCES;MARINE & FRESHWATER BIOLOGY 2020 5.553 2.3 1.91 2025-06-25 26 33 Bacteria; Biofilm; CO2; Ocean acidification; Plastics; Plastisphere CARBON-DIOXIDE; MICROBIAL BIOFILMS; DIVERSITY; SEA; COLONIZATION; HITCHHIKERS; ABUNDANCE; LITTER; LIFE Bacteria; Biofilm; CO<sub>2</sub>; Ocean acidification; Plastics; Plastisphere Bacteria; Hydrogen-Ion Concentration; Oceans and Seas; Plastics; Seawater; Bacteria (microorganisms); Acidification; Bacteria; Biofilms; Elastomers; bacterial DNA; carbon dioxide; plastic; sea water; Bacterial community; Coastal communities; Deoxygenations; Marine environment; Marine plastics; Microbial communities; Ocean acidifications; Plastic wastes; acidification; biofilm; carbon dioxide; marine pollution; microbial community; plastic waste; pollution effect; Article; bacterial colonization; biofilm; community dynamics; controlled study; drinking bottle; microbial community; microbial diversity; nonhuman; ocean acidification; plastic pollution; plastic waste; polymerase chain reaction; sea pollution; seashore; sequence analysis; species composition; species richness; bacterium; pH; sea; Oceanography English 2020 2020-12 10.1016/j.marpolbul.2020.111749 바로가기 바로가기 바로가기 바로가기
Article Output-Constrained Robust Sliding Mode Based Nonlinear Active Suspension Control The nonlinear active suspension control design can be analyzed as a multiobjective control problem that caters to the enhancement in ride comfort levels while ensuring that road holding is maintained with the constrained suspension displacement movement. In this article, a robust constrained output feedback approach employing sliding mode controllers is proposed for the nonlinear active suspension system equipped with hydraulic actuators. Adhering to mechanical design limitations, the suspension displacement and the corresponding displacement rate are constrained using asymmetric barrier Lyapunov functions. Consequently, a nonlinear control law that incorporates the first-order sliding mode control is then formulated to regulate the hydraulic valve and thereby provide an active control effort. The robust control performance with high-performance improvements for ride comfort in the presence of parametric uncertainties, sensor noise, and over variable driving velocities for different road conditions is established using simulation studies. Rath, Jagat Jyoti; Defoort, Michael; Sentouh, Chouki; Karimi, Hamid Reza; Veluvolu, Kalyana Chakravarthy Polytech Univ Hauts de France, LAMIH, UMR CNRS 8201, F-59313 Valenciennes, France; Tech Univ Munich, Dept Informat, D-85748 Garching, Germany; Politecn Milan, Dept Mech Engn, I-20156 Milan, Italy; Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 702701, South Korea Rath, Jagat Jyoti/H-8639-2013; Veluvolu, Kalyana Chakravarthy/C-6366-2011; Karimi, Hamid Reza/Y-2403-2019; Veluvolu, Kalyana/C-6366-2011; Rath, Jagat/AAF-6698-2019 55904945200; 23008315300; 24528847400; 59268604900; 8703318200 jagat.cmeri@gmail.com;michael.defoort@uphf.fr;chouki.sentouh@univ-valenciennes.fr;hamidreza.karimi@polimi.it;veluvolu@ee.knu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 67 12 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2020 8.236 2.3 2.79 2025-06-25 57 60 Suspensions; Roads; Robustness; Hydraulic actuators; Vehicle dynamics; Springs; Active suspension control (ASC); barrier Lyapunov functions (BLFs); constrained control H-INFINITY CONTROL; MULTIOBJECTIVE CONTROL; LYAPUNOV FUNCTIONS; SYSTEMS Active suspension control (ASC); barrier Lyapunov functions (BLFs); constrained control Active suspension systems; Hydraulic actuators; Lyapunov functions; Roads and streets; Robust control; Sliding mode control; Active suspension control; Control performance; Multi-objective control; Nonlinear active suspension systems; Nonlinear control laws; Parametric uncertainties; Robust sliding mode; Sliding mode controller; Suspensions (components) English 2020 2020-12 10.1109/tie.2020.2978693 바로가기 바로가기 바로가기 바로가기
Article Overexpression of Activin Receptor-Like Kinase 1 in Endothelial Cells Suppresses Development of Arteriovenous Malformations in Mouse Models of Hereditary Hemorrhagic Telangiectasia Rationale: Hereditary hemorrhagic telangiectasia (HHT) is a genetic disease caused by mutations inENG,ALK1, orSMAD4. Since proteins from all 3 HHT genes are components of signal transduction of TGF-beta (transforming growth factor beta) family members, it has been hypothesized that HHT is a disease caused by defects in the ENG-ALK1-SMAD4 linear signaling. However, in vivo evidence supporting this hypothesis is scarce. Objective: We tested this hypothesis and investigated the therapeutic effects and potential risks of induced-ALK1 or -ENG overexpression (OE) for HHT. Methods and Results: We generated a novel mouse allele (ROSA26(Alk1)) in which HA (human influenza hemagglutinin)-tagged ALK1 and bicistronic eGFP expression are induced by Cre activity. We examined whether ALK1-OE using the ROSA26(Alk1)allele could suppress the development of arteriovenous malformations (AVMs) in wounded adult skin and developing retinas ofAlk1- andEng-inducible knockout (iKO) mice. We also used a similar approach to investigate whether ENG-OE could rescue AVMs. Biochemical and immunofluorescence analyses confirmed the Cre-dependent OE of the ALK1-HA transgene. We could not detect any pathological signs in ALK1-OE mice up to 3 months after induction. ALK1-OE prevented the development of retinal AVMs and wound-induced skin AVMs inEng-iKO as well asAlk1-iKO mice. ALK1-OE normalized expression of SMAD and NOTCH target genes in ENG-deficient endothelial cells (ECs) and restored the effect of BMP9 (bone morphogenetic protein 9) on suppression of phosphor-AKT levels in these endothelial cells. On the other hand, ENG-OE could not inhibit the AVM development inAlk1-iKO models. Conclusions: These data support the notion that ENG and ALK1 form a linear signaling pathway for the formation of a proper arteriovenous network during angiogenesis. We suggest that ALK1 OE or activation can be an effective therapeutic strategy for HHT. Further research is required to study whether this therapy could be translated into treatment for humans. Kim, Yong Hwan; Phuong-Nhung Vu; Choe, Se-Woon; Jeon, Chang-Jin; Arthur, Helen M.; Vary, Calvin P. H.; Lee, Young Jae; Oh, S. Paul Univ Florida, Coll Med, Dept Physiol & Funct Genom, Gainesville, FL USA; Barrow Neurol Inst, Dept Neurobiol, Phoenix, AZ 85013 USA; Gachon Univ, Lee Gil Ya Canc & Diabet Inst, 155 Gaetbeol Ro, Incheon 21999, South Korea; Kumoh Natl Inst Technol, Dept Med IT Convergence Engn, Gumi, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Biol, Daegu, South Korea; Newcastle Univ, Inst Genet Med, Newcastle Upon Tyne, Tyne & Wear, England; Maine Med Ctr Res Inst, Ctr Mol Med, Scarborough, ME USA ; Kim, Yong/AAL-8113-2021; Arthur, Helen/C-7808-2009; Lee, Da Young/AAA-1843-2021 57219445308; 57215505714; 34970866700; 7006894339; 7006480452; 7003334423; 57219688287; 7404103532 leeyj@gachon.ac.kr;ohp@barrowneuro.org; CIRCULATION RESEARCH CIRC RES 0009-7330 1524-4571 127 9 SCIE CARDIAC & CARDIOVASCULAR SYSTEMS;HEMATOLOGY;PERIPHERAL VASCULAR DISEASE 2020 17.367 2.3 1.86 2025-06-25 41 36 activin receptor-like kinase 1; arteriovenous malformation; endoglin; endothelial cell; hereditary hemorrhagic telangiectasia; mice; signal transduction JUVENILE POLYPOSIS; ALK1; ENDOGLIN; HHT; EXPRESSION; MUTATIONS; PROTEIN; GENE; EPISTAXIS; MIGRATION activin receptor-like kinase 1; arteriovenous malformation; endoglin; endothelial cell; hereditary hemorrhagic telangiectasia; mice; signal transduction Activin Receptors, Type II; Alleles; Animals; Apoptosis Regulatory Proteins; Arteriovenous Malformations; Disease Models, Animal; Endoglin; Endothelial Cells; Green Fluorescent Proteins; Growth Differentiation Factor 2; Mice; Mitochondrial Proteins; Receptors, Notch; Retinal Vessels; RNA, Untranslated; Signal Transduction; Skin; Smad4 Protein; Telangiectasia, Hereditary Hemorrhagic; Transforming Growth Factor beta; activin receptor 2; Acvrl1 protein, mouse; apoptosis regulatory protein; bone morphogenetic protein 9; Diablo protein, mouse; endoglin; Eng protein, mouse; enhanced green fluorescent protein; green fluorescent protein; Gt(ROSA)26Sor non-coding RNA, mouse; mitochondrial protein; Notch receptor; Smad4 protein; Smad4 protein, mouse; transforming growth factor beta; untranslated RNA; allele; animal; arteriovenous malformation; disease model; endothelium cell; genetics; injury; metabolism; mouse; Rendu Osler Weber disease; retina blood vessel; signal transduction; skin; vascularization English 2020 2020-10-09 10.1161/circresaha.119.316267 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Prognostic Positioning of EGFR Mutated Advanced Lung Cancer in Relation to the Treatment Modalities Choi, W.; Jeong, J.; Lee, C. Keimyung Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Sungso Hosp, Dept Occupat & Environm Med, Andong, South Korea wichoi@dsmc.or.kr; AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE AM J RESP CRIT CARE 1073-449X 1535-4970 201 SCIE CRITICAL CARE MEDICINE;RESPIRATORY SYSTEM 2020 21.405 2.3 0 English 2020 2020 바로가기 바로가기
Meeting Abstract Quantitative Assessment of Airway Narrowing, Wall Thickening, and Alteration of Branching Angle in Subjects with Cement Dust Exposure Choi, S.; Cho, H.; Kim, T.; Kim, W.; Lee, C.; Chae, K.; Bak, S.; Kwon, S.; Jin, G.; Park, E.; Choi, J.; Lin, C.; Hoffman, E. A. Kyungpook Natl Univ, Engn, Daegu, South Korea; Kangwon Natl Univ Hosp, Chunchon, South Korea; Seoul Natl Univ Hosp, Seoul, South Korea; Chonbuk Natl Univ Hosp, Jeonju, South Korea; Kosin Univ, Busan, South Korea; Univ Iowa, Iowa City, IA USA Choi, Sanghun/AGS-7430-2022 s-choi@knu.ac.kr; AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE AM J RESP CRIT CARE 1073-449X 1535-4970 201 SCIE CRITICAL CARE MEDICINE;RESPIRATORY SYSTEM 2020 21.405 2.3 0 English 2020 2020 바로가기 바로가기
Article Advanced target-specific probe-based real-time loop-mediated isothermal amplification assay for the rapid and specific detection of porcine circovirus 3 Porcine circovirus type 3 (PCV3) is an emerging viral pathogen that has been identified in pigs with various clinical signs. For rapid and specific detection of PCV3, an advanced real-time loop-mediated isothermal amplification (rLAMP) assay that uses both assimilating probes and swarm primers were developed and evaluated in this study. The assay specifically amplified PCV3 DNA, but it did not amplify other porcine viral nucleic acids. The limit of detection of rLAMP with swarm primers was 50 PCV3 DNA copies/reaction, which was comparable to that of the real-time quantitative polymerase chain reaction (qPCR) and 10 times more sensitive than rLAMP without swarm primers. In an evaluation of clinical samples, the rLAMP assay was able to detect PCV3 DNA within 17.34 +/- 4.45 min, which is more rapid than what has been previously reported for the standard qPCR assay (31.78 +/- 4.60 min). Detection with rLAMP was largely in agreement with that of the qPCR with a kappa value (95% confidence interval) of 0.98 (0.95-1.00). Taken together, these results suggest that the rLAMP assay presented will be a valuable tool for rapid, specific and reliable diagnosis of PCV3 in clinical samples. Kim, Hye-Ryung; Lim, Da-Rae; Chae, Ha-Gyeong; Park, Ji-Young; Kim, Seong-Hee; Lee, Kyoung-Ki; Lee, Changhee; Lyoo, Young S.; Park, Choi-Kyu Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Anim Dis Intervent Ctr, Daegu 41566, South Korea; Anim & Plant Quarantine Agcy, Anim Dis Diagnost Div, Gimcheon, South Korea; Kyungpook Natl Univ, Sch Life Sci, Anim Virol Lab, Daegu, South Korea; Konkuk Univ, Coll Vet Med, Seoul, South Korea 57195772612; 57195776777; 57202787553; 56095792500; 34769762800; 38163138800; 55700560700; 35501431200; 24768064900 parkck@knu.ac.kr; TRANSBOUNDARY AND EMERGING DISEASES TRANSBOUND EMERG DIS 1865-1674 1865-1682 67 6 SCIE INFECTIOUS DISEASES;VETERINARY SCIENCES 2020 5.005 2.4 0.78 2025-06-25 10 8 assimilating probe; porcine circovirus 3; real-time LAMP; swarm primer LAMP; PERFORMANCE; GUIDELINES assimilating probe; porcine circovirus 3; real-time LAMP; swarm primer Animals; Circoviridae Infections; Circovirus; Communicable Diseases, Emerging; DNA Primers; DNA Probes; Molecular Diagnostic Techniques; Nucleic Acid Amplification Techniques; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Swine; Swine Diseases; 6 carboxyfluorescein; betaine; plasmid DNA; primer DNA; primer RNA; animal cell; Article; cloning vector; controlled study; diagnostic test accuracy study; DNA extraction; DNA isolation; fluorescence; limit of detection; loop mediated isothermal amplification; measurement precision; measurement repeatability; nonhuman; nucleotide sequence; pig; PK-15 cell line; Porcine circovirus 2; real time polymerase chain reaction; reproducibility; RNA extraction; sensitivity and specificity; virus detection; animal; Circoviridae infection; Circovirus; communicable disease; DNA probe; genetics; isolation and purification; molecular diagnosis; nucleic acid amplification; swine disease; veterinary medicine; virology English 2020 2020-11 10.1111/tbed.13671 바로가기 바로가기 바로가기 바로가기
Article Atomistic investigation of the effect of contact condition on frictional properties of nanowire At the nanoscale, the interfacial shear strength is often determined without considering the uncertainty in the contact condition. The contact between flat surfaces is particularly obscure because of their atomic-level irregularities. This study conducts molecular dynamics simulations to investigate the contact condition between nominally flat surfaces. Simulations using nanowires with flat and rough surfaces are conducted to assess the interfacial shear strength involved with the contact condition. The simulation result shows that the interfacial shear strength of the nanowire with a flat surface is 1.9 MPa. Although a rough nanowire has a much smaller real contact area than the flat nanowire, the rough nanowire exhibits similar frictional force and much greater shear strength (22.8 MPa) compared to the flat nanowire. The distance between the nanowire and the substrate is examined to reveal the mechanism, and the rough nanowire showed a shorter distance than the flat nanowire. The shorter distance is attributed to the concentrated normal force at the contact junction and causes a high frictional force per contact area because of its larger potential energy barrier. The interfacial shear strength can feasibly be underestimated for a nominally flat-facet nanowire. Kim, Hyun-Joon; Chung, Koo-Hyun Kyungpook Natl Univ, Dept Precis Mech Engn, 2559 Gyeonsangdae Ro, Sangju 37224, South Korea; Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, 2559 Gyeonsangdae Ro, Sangju 37224, South Korea; Univ Ulsan, Sch Mech Engn, 93 Daehak Ro, Ulsan 44610, South Korea Chung, Koo-Hyun/M-8337-2019 56766313200; 7404086064 khchung@ulsan.ac.kr; APPLIED SURFACE SCIENCE APPL SURF SCI 0169-4332 1873-5584 534 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, COATINGS & FILMS;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER 2020 6.707 2.4 0.27 2025-06-25 8 8 Molecular dynamics simulation; Contact condition; ZnO nanowire; Manipulation; Contact area; Shear strength MOLECULAR-DYNAMICS SIMULATION; ZNO NANOWIRE; ELASTIC PROPERTIES; SURFACE-ROUGHNESS; KINETIC FRICTION; BEHAVIOR; MECHANISM; GROWTH Contact area; Contact condition; Manipulation; Molecular dynamics simulation; Shear strength; ZnO nanowire Friction; Molecular dynamics; Potential energy; Concentrated normal force; Contact conditions; Frictional forces; Frictional properties; Interfacial shear strength; Molecular dynamics simulations; Real contact area; Rough nanowires; Nanowires English 2020 2020-12-30 10.1016/j.apsusc.2020.147629 바로가기 바로가기 바로가기 바로가기
Article Carbon-derived from metal-organic framework MOF-74: A remarkable adsorbent to remove a wide range of contaminants of emerging concern from water Five typical Zn-based metal-organic frameworks (MOFs) such as MOF-74(Zn) were pyrolyzed to obtain carbons-derived from MOFs (CDMs). The carbon-derived from MOF-74(Zn) or CDM-74 was firstly applied, together with other four CDMs and commercial activated carbon (AC), in the adsorptive removal of five representative contaminants of emerging concern (CECs) such as phthalic acid, diethyl phthalate, N,N-diethyl-3-methylbenzamide (DEET), chloroxylenol (CLXN) and oxybenzone (OXB) from water. CDM-74, with high mesopore volume and acid sites density, showed the highest capacity for the adsorption of DEET, OXB and CLXN from water among the tested and any reported adsorbent, so far. The plausible adsorption mechanism could be suggested, or H-bonding was important in the adsorption where the DEET and CDM-74 (especially phenolics) can be H-acceptor and H-donor, respectively. Based on the highest adsorption capacity for three adsorbates and facile recyclability, CDM-74 could be suggested as a potential adsorbent to eliminate a wide range of CECs from water. Bhadra, Biswa Nath; Yoo, Dong Kyu; Jhung, Sung Hwa Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea Bhadra, Biswa Nath/ABG-6935-2021; Bhadra, Biswa/ABG-6935-2021; Jhung, Sung/AAO-6683-2021 56982844300; 57201339246; 6701659467 sung@knu.ac.kr; APPLIED SURFACE SCIENCE APPL SURF SCI 0169-4332 1873-5584 504 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, COATINGS & FILMS;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER 2020 6.707 2.4 3.43 2025-06-25 61 66 Adsorption; Carbon-derived from MOFs; Contaminants of emerging concern; Mechanism; Metal-organic frameworks; MOF-74 PERSONAL CARE PRODUCTS; DOPED POROUS CARBONS; ADSORPTIVE REMOVAL; AQUATIC ENVIRONMENT; NANOPOROUS CARBON; HIGH-PERFORMANCE; SURFACE-AREA; BISPHENOL-A; CO2 CAPTURE; NITROGEN Adsorption; Carbon-derived from MOFs; Contaminants of emerging concern; Mechanism; Metal-organic frameworks; MOF-74 Activated carbon; Adsorption; Crystalline materials; Mechanisms; Organic polymers; Organometallics; Adsorption capacities; Adsorption mechanism; Commercial activated carbons; Contaminants of emerging concerns; Metal organic framework; Metalorganic frameworks (MOFs); MOF-74; Potential adsorbents; Chemicals removal (water treatment) English 2020 2020-02-28 10.1016/j.apsusc.2019.144348 바로가기 바로가기 바로가기 바로가기
Article Cobalt- and iron-coordinated graphitic carbon nitride on reduced graphene oxide: A nonprecious bimetallic M-Nx-C analogue electrocatalyst for efficient oxygen reduction reaction in acidic media The electrocatalytic oxygen reduction reaction (ORR) in acidic media is quite strenuous. Although platinum (Pt)-based materials are considered state-of-the-art ORR catalysts, their high cost and poor durability greatly impede their extensive application in polymer electrolyte membrane fuel cells and direct methanol fuel cells. Here, we report a bimetallic M-N-x-C-class electrocatalyst comprising Co- and Fe-coordinated graphitic carbon nitride ((Co,Fe)-CN) and reduced graphene oxide (RGO) as an effective substitute for expensive Pt-based catalysts for the ORR in acidic media. The fabricated (Co,Fe)-CN/RGO catalyst exhibits a high surface area, high porosity, fast charge-transfer kinetics at the (Co,Fe)-CN/RGO 2D/2D interface, and abundant Co-Nx-C and Fe-N-x-C active sites. Because of these favorable properties, the optimized (Co,Fe)-CN/RGO catalyst displayed extra-ordinary electrocatalytic ORR activity, with an onset potential of 875 mV, which is only 41 mV more negative than that of a commercial Pt/C, and follows an efficient four-electron reaction pathway in acidic media. Notably, the fabricated catalyst demonstrated excellent methanol tolerance and long-term stability compared with the reference Pt/C. Therefore, this work provides a rational design approach to fabricating graphitic-C3N4-based nonprecious bimetallic electrocatalysts with M-N-x-C active sites for enhanced ORR activity in fuel-cell applications. Jo, Wan-Kuen; Moru, Satyanarayana; Lee, Dong-Eun; Tonda, Surendar Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Iowa State Univ, Dept Elect & Comp Engn, Coover Hall,Osborn Dr, Ames, IA 50011 USA; Kakatiya Inst Technol & Sci, Dept Phys Sci, Warangal 506015, Telangana, India; Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, 80 Daehak Ro, Daegu 41566, South Korea Tonda, Surendar/AAO-3358-2020; MORU, SATYANARAYANA/AAF-3189-2021; Jo, Wan/AAO-5329-2020; Moru, Satyanarayana/AAF-3189-2021 7103322277; 58562229700; 56605563300; 56114866900 surendart@knu.ac.kr; APPLIED SURFACE SCIENCE APPL SURF SCI 0169-4332 1873-5584 531 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, COATINGS & FILMS;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER 2020 6.707 2.4 2.22 2025-06-25 36 35 g-C3N4; Bimetallic; Nonprecious catalyst; Electrocatalysis; Oxygen reduction reaction HIGH-PERFORMANCE ELECTROCATALYSTS; HIGHLY EFFICIENT; BIFUNCTIONAL ELECTROCATALYST; ORGANIC FRAMEWORK; FUEL-CELLS; CATALYST; HYBRID; G-C3N4; FE; ALKALINE Bimetallic; Electrocatalysis; g-C<sub>3</sub>N<sub>4</sub>; Nonprecious catalyst; Oxygen reduction reaction Catalyst activity; Charge transfer; Cobalt; Coordination reactions; Direct methanol fuel cells (DMFC); Electrocatalysts; Electrolytic reduction; Graphene; Graphitic Carbon Nitride; Iron compounds; Methanol; Methanol fuels; Oxygen; Oxygen reduction reaction; Polyelectrolytes; Proton exchange membrane fuel cells (PEMFC); Reduced Graphene Oxide; Bimetallic electrocatalysts; Charge transfer kinetics; Electrocatalytic oxygen reduction; Fuel cell application; Long term stability; Methanol tolerance; Reaction pathways; Reduced graphene oxides (RGO); C (programming language) English 2020 2020-11-30 10.1016/j.apsusc.2020.147367 바로가기 바로가기 바로가기 바로가기
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