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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Optical Multisensor Array with Functionalized Photonic Droplets by an Interpenetrating Polymer Network for Human Blood Analysis Photonic solid-state cholesteric liquid crystal (CLCsolid) droplets intertwined with a poly(acrylic acid) (PAA) network that has an interpenetrating polymer network (IPN) structure (referred to as photonic IPN CLCsolid-PAA droplets) were used as individual sensors in the dots of a PAA-patterned array film after functionalization via immobilization of the receptors and a metal-ion treatment. The photonic IPN CLCsolid-PAA droplets in the PAA-patterned array film were pH-responsive and showed an observable change in the reflected central color. This "smart" property, coupled with the photonic color response, makes these devices ideal photonic sensors. The immobilization of urease and phenylboronic acid on the PAA network allowed for the application of several 10 mu m photonic IPN CLCsolid-PAA droplets to the optical photonic biosensors through facilitated volumetric changes in the PAA network in response to urea and glucose analytes, with high selectivity for major components in human serum, acceptable sensitivity for use with human serum, and extreme stability due to a solid-state structure. The blueshift of the reflected color of the KOH-treated photonic IPN CLCsolid-PAA droplets could be used for divalent metal-ion detection. The compartmentalized photonic IPN CLCsolid-PAA droplets in the patterned array film could be used for multiple detection applications, as evidenced by the ability to conduct pH, divalent metal ion, urea, and glucose detections in one patterned array film. This new platform opens the door for many interesting applications with numerous combinations of responsive hydrogel matrices and receptors. Kim, Ye-Ji; Park, Soo-Young Kyungpook Natl Univ, Sch Appl Chem Engn, Polymer Nano Mat Lab, Daegu 41566, South Korea park, soo-young/N-3170-2017 57219616711; 57194041850 psy@knu.ac.kr; ACS APPLIED MATERIALS & INTERFACES ACS APPL MATER INTER 1944-8244 1944-8252 12 42 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 0.93 2025-06-25 25 25 photonic array; interpenetrating polymer network; microfluidics; biosensor; cholesteric liquid crystal DIVALENT-CATIONS; LIQUID-CRYSTALS; BINDING; ACID; FABRICATION; BIENZYME; GLUCOSE Biosensor; Cholesteric liquid crystal; Interpenetrating polymer network; Microfluidics; Photonic array Acrylic Resins; Biosensing Techniques; Blood Glucose; Humans; Hydrogen-Ion Concentration; Liquid Crystals; Particle Size; Photons; Surface Properties; Urea; Cholesteric liquid crystals; Color; Crystal structure; Glucose; Metabolism; Metal ions; Metals; Organic acids; Potassium hydroxide; Sensor arrays; Solid-state sensors; Urea; acrylic acid resin; carbopol 940; urea; Interpenetrating polymer network (IPN); Multi-sensor arrays; Multiple detection; Phenylboronic acids; Photonic biosensor; Responsive hydrogels; Solid-state structures; Volumetric changes; blood; chemistry; genetic procedures; glucose blood level; human; liquid crystal; particle size; pH; photon; surface property; Drops English 2020 2020-10-21 10.1021/acsami.0c15718 바로가기 바로가기 바로가기 바로가기
Article Possible Charge Density Wave and Enhancement of Thermoelectric Properties at Mild-Temperature Range in n-Type Cul-Doped Bi2Te2.1Se0.9 Compounds Bi2Te3-based compounds have long been studied as thermoelectric materials in cooling applications near room temperature. Here, we investigated the thermoelectric properties of CuI-doped Bi2Te2.1Se0.9 compounds. The Cu/I codoping induces the lattice distortion partially in the matrix. We report that the charge density wave caused by the local lattice distortion affects the electrical and thermal transport properties. From the high-temperature specific heat, we found a first-order phase transitions near 490 and 575 K for CuI-doped compounds (CuI)(x)Bi2Te2.1Se0.9 (x = 0.3 and 0.6%), respectively. It is not a structural phase transition, confirming from the high-temperature X-ray diffraction. The temperature-dependent electrical resistivity shows a typical behavior of charge density wave transition, which is consistent with the temperature-dependent Seebeck coefficient and thermal conductivity. The transmission electron microscopy and electron diffraction show a local lattice distortion, driven by the charge density wave transition. The charge density wave formation in the Bi2Te3-based compounds are exceptional because of the possibility of coexistence of charge density wave and topological surface states. From the Kubo formula and Boltzmann transport calculations, the formation of charge density wave enhances the power factor. The lattice modulation and charge density wave decrease lattice thermal conductivity, resulting in the enhancement of thermoelectric performance simultaneously in CuI-doped samples. Consequently, an enhancement of thermoelectric performance ZT over 1.0 is achieved at 448 K in the (CuI)(0.003)Bi(2)Te(2)ASe(0.9) sample. The enhancement of ZT at high temperature gives rise to a superior average ZT(avg) (1.0) value than those of previously reported ones. Cho, Hyunyong; Yun, Jae Hyun; Kim, Jin Hee; Back, Song Yi; Lee, Ho Seong; Kim, Sung Jin; Byeon, Seokyeong; Jin, Hyungyu; Rhyee, Jong-Soo Kyung Hee Univ, Dept Appl Phys, Gyung Gi 17104, South Korea; Kyung Hee Univ, Inst Nat Sci, Gyung Gi 17104, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 03760, South Korea; Pohang Univ Sci & Technol, Dept Mech Engn, Pohang 37673, South Korea ; Rhyee, Jong-Soo/AAK-7173-2020; Jin, Hyungyu/AAW-3427-2020; Kim, Sung-Jin/AAP-9165-2021; Back, Song Yi/ABP-6733-2022; KIM, YOUNG JIN/E-9374-2011 57196076542; 57189224964; 57194613785; 57196079077; 55706810400; 56812714700; 57204911394; 58291407900; 6603282348 jsrhyee@khu.ac.kr; ACS APPLIED MATERIALS & INTERFACES ACS APPL MATER INTER 1944-8244 1944-8252 12 1 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 1.1 2025-06-25 30 30 Bi2Te3; codoping; thermoelectric; charge density wave; lattice modulation; phase transition ORGANIC RANKINE-CYCLE; WASTE HEAT; PERFORMANCE; EFFICIENCY; POINT; POWER; BI2TE2.7SE0.3; DISTORTION; ALLOYS Bi<sub>2</sub>Te<sub>3</sub> ; charge density wave; codoping; lattice modulation; phase transition; thermoelectric Bismuth compounds; Charge density; Copper compounds; High resolution transmission electron microscopy; Modulation; Phase transitions; Selenium compounds; Specific heat; Tellurium compounds; Thermal conductivity; Thermoelectric equipment; Thermoelectricity; Bi2Te3; Boltzmann transport calculations; Charge density wave formation; Co-doping; First-order phase transitions; High temperature X-ray diffraction; Lattice modulations; thermoelectric; Charge density waves English 2020 2020-01-08 10.1021/acsami.9b19398 바로가기 바로가기 바로가기 바로가기
Article Prunus serrulata var. spontanea inhibits mast cell activation and mast cell-mediated anaphylaxis Ethnopharmacological relevance: A promising approach to treat a variety of diseases are considered as complementary and alternative herbal medicines. Prunus serrulata var. spontanea L. (Rosaceae) is used as herbal medicine to treat allergic diseases according to the Donguibogam, a tradition medical book of the Joseon Dynasty in Korea. Aim of the study: We prepared the aqueous extract of the bark of P. serrulata (AEBPS) and aimed to investigate the effects in mouse anaphylaxis models and various types of mast cells, including RBL-2H3, primary cultured peritoneal and bone marrow-derived mast cells. Materials and methods: We used ovalbumin (OVA)-induced active systemic anaphylaxis (ASA) and immunoglobulin (Ig) E-mediated passive cutaneous anaphylaxis (PCA) models, in vivo. The control drug dexamethasone (10 mg/kg) was used to compare the effectiveness of AEBPS (1-100 mg/kg). In vitro, IgE-stimulated mast cells were used to confirm the role of AEBPS (1-100 mu g/mL). For statistical analyses, p values less than 0.05 were considered to be significant. Results: In ASA model, oral administration of AEBPS suppressed the hypothermia and increased level of serum histamine in a dose-dependent manner. AEBPS attenuated the serum IgE, OVA-specific IgE, and interleukin (IL)-4. Oral administration of AEBPS also blocked mast cell-dependent PCA. AEBPS suppressed degranulation of mast cells by reducing intracellular calcium level in mast cells. AEBPS inhibited tumor necrosis factor-a and IL-4 expression and secretion in a concentration-dependent manner through the reduction of nuclear factor-kappa B. Conclusions: On the basis of these findings, AEBPS could serve as a potential therapeutic target for the management of mast cell-mediated allergic inflammation and as a regulator of mast cell activation. Kim, Min-Jong; Choi, Young-Ae; Lee, Soyoung; Choi, Jin Kyeong; Kim, Yeon-Yong; Kim, Eun-Nam; Jeong, Gil-Saeng; Shin, Tae-Yong; Jang, Yong Hyun; Kim, Sang-Hyun Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Cell & Matrix Res Inst, Daegu, South Korea; Korea Res Inst Biosci & Biotechnol, Immunoregulatory Mat Res Ctr, Jeongeup, South Korea; NEI, Mol Immunol Sect, Lab Immunol, NIH, Bethesda, MD 20892 USA; Keimyung Univ, Coll Pharm, Daegu, South Korea; Woosuk Univ, Coll Pharm, Jeonju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Dermatol, 130 Dongdeok Ro, Daegu 41944, South Korea 57192888932; 7404777420; 8537269200; 50261279600; 57190027396; 57201655294; 57204396456; 7201493155; 57016046400; 57210450420 yhjang@knu.ac.kr;shkim72@knu.ac.kr; JOURNAL OF ETHNOPHARMACOLOGY J ETHNOPHARMACOL 0378-8741 1872-7573 250 SCIE CHEMISTRY, MEDICINAL;INTEGRATIVE & COMPLEMENTARY MEDICINE;PHARMACOLOGY & PHARMACY;PLANT SCIENCES 2020 4.36 13.0 0.27 2025-06-25 4 4 Prunus serrulata; Active systemic anaphylaxis; Immunoglobulin E; Passive cutaneous anaphylaxis; Histamine; Mast cells NF-KAPPA-B; TUMOR-NECROSIS-FACTOR; ALLERGIC INFLAMMATION; BETULA-PLATYPHYLLA; HISTAMINE-RELEASE; FACTOR-ALPHA; DEGRANULATION; IGE; DEGRADATION; SUPPRESSION Active systemic anaphylaxis; Histamine; Immunoglobulin E; Mast cells; Passive cutaneous anaphylaxis; Prunus serrulata Anaphylaxis; Animals; Dose-Response Relationship, Drug; Histamine; Immunoglobulin E; Male; Mast Cells; Medicine, Korean Traditional; Mice; Mice, Inbred ICR; Ovalbumin; Passive Cutaneous Anaphylaxis; Plant Bark; Plant Extracts; Prunus; Rats; Rats, Sprague-Dawley; antiinflammatory agent; calcium; dexamethasone; immunoglobulin E; immunoglobulin enhancer binding protein; interleukin 4; ovalbumin; plant extract; Prunus serrulata extract; tumor necrosis factor; unclassified drug; histamine; ovalbumin; plant extract; animal cell; animal experiment; animal model; animal tissue; antiinflammatory activity; Article; bark; bone marrow derived mast cell; calcium cell level; cell activation; comparative effectiveness; controlled study; degranulation; histamine blood level; hypothermia; in vitro study; in vivo study; male; mast cell; nonhuman; passive skin anaphylaxis; peritoneum mast cell; Prunus; Prunus serrulata var. spontanea; rat; systemic anaphylaxis; anaphylaxis; animal; blood; chemistry; dose response; drug effect; immunology; Institute for Cancer Research mouse; Korean medicine; mast cell; mouse; passive skin anaphylaxis; Prunus; Sprague Dawley rat English 2020 2020-03-25 10.1016/j.jep.2019.112484 바로가기 바로가기 바로가기 바로가기
Article Realization of Biomimetic Synaptic Functions in a One-Cell Organic Resistive Switching Device Using the Diffusive Parameter of Conductive Filaments Toward the successful development of artificial intelligence, artificial synapses based on resistive switching devices are essential ingredients to perform information processing in spiking neural networks. In neural processes, synaptic plasticity related to the history of neuron activity plays a critical role during learning. In resistive switching devices, it is barely possible to emulate both short-term plasticity and long-term plasticity due to the uncontrollable dynamics of the conductive filaments (CFs). Despite extensive effort to realize synaptic plasticity in such devices, it is still challenging to achieve reliable synaptic functions due to the overgrowth of CFs in a random fashion. Herein, we propose an organic resistive switching device with bio-realistic synaptic functions by adjusting the CF diffusive parameter. In the proposed device, complete synaptic plasticity provides the history-dependent change in the conductance. Moreover, the homeostatic feedback, which resembles the biological process, regulates CF growth in our device, which enhances the reliability of synaptic plasticity. This novel concept for realizing synaptic functions in organic resistive switching devices may provide a physical platform to advance the fundamental understanding of learning and memory mechanisms and develop a variety of neural circuits and neuromorphic systems that can be linked to artificial intelligence and next-generation computing paradigm. © 2020 American Chemical Society. Lee, Sin-Hyung; Park, Hea-Lim; Kim, Min-Hoi; Kim, Min-Hwi; Park, Byung-Gook; Lee, Sin-Doo School of Electronics Engineering, School of Electronic and Electrical Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu, 702-701, South Korea; Department of Materials Science and Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; Department of Creative Convergence Engineering, Hanbat National University, Yuseong-gu, Daejeon, 305-719, South Korea; School of Electrical and Computer Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; School of Electrical and Computer Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; School of Electrical and Computer Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea 57226880204; 55735654600; 38260922200; 56647038300; 7402834279; 34974364800 sinhlee@knu.ac.kr; ACS Applied Materials and Interfaces ACS APPL MATER INTER 1944-8244 1944-8252 12 46 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 0.82 2025-06-25 27 artificial synapse; conductive filament; organic resistive switching device; spiking neural networks; synaptic function; synaptic plasticity Artificial intelligence; Biomimetics; Electron emission; Computing paradigm; Conductive filaments; Learning and memory; Neuromorphic systems; Resistive switching devices; Short term plasticity; Spiking neural networks; Synaptic plasticity; article; artificial intelligence; conductance; learning; memory; nerve cell plasticity; reliability; spiking neural network; Switching English Final 2020 10.1021/acsami.0c15519 바로가기 바로가기 바로가기
Article Removal of Particulate Matters with Isostructural Zr-Based Metal-Organic Frameworks Coated on Cotton: Effect of Porosity of Coated MOFs on Removal Effective removal of particulate matters (PMs) from air is very important for our safe environment, health, and sustainability. In this study, isostructural (with the same topology of fcu) Zr-metal-organic frameworks (Zr-MOFs) such as UiO-66, UiO-67, and DUT-52 (with different porosity) were coated onto cotton and utilized in PM removal from air to understand the contribution of MOFs in improving the performances of air filters. Moreover, UiO-66s with different porosities were also prepared under different conditions from the same reaction mixture. Experiments to remove PMs such as PM2.5 and PM10 showed a critical role of porosity of coated MOFs in the PM removal. Or, the removal efficiency or quality factor increased linearly with the increasing surface area of all the studied MOFs, irrespective of the applied linkers (for synthesizing different MOFs) and synthesis conditions (for different porosities of UiO-66s). Therefore, this work confirms, for the first time, that the porosity of MOF is one of the most important parameters to improve the performance of air filter (to remove PMs) that is modified with coated MOFs. Moreover, we could suggest why porous materials with small pores were effective in capturing PMs (larger in size than pores of porous materials) from air. Yoo, Dong Kyu; Woo, Hochul; Jhung, Sung Hwa Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea ; Jhung, Sung/AAO-6683-2021 57201339246; 57217234591; 6701659467 sung@knu.ac.kr; ACS APPLIED MATERIALS & INTERFACES ACS APPL MATER INTER 1944-8244 1944-8252 12 30 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 1.48 2025-06-25 0 40 air filter; metal-organic framework; particulate matter; porosity; removal; surface area ZEOLITIC IMIDAZOLATE FRAMEWORK-8; IN-SITU GROWTH; AIR FILTERS; FIBROUS MEMBRANES; HIGHLY EFFICIENT; GAS-ADSORPTION; PM2.5 CAPTURE; STABILITY; FIBER; DESIGN air filter; metal-organic framework; particulate matter; porosity; removal; surface area Air filters; Cotton; Metal-Organic Frameworks; Organometallics; Porous materials; Sustainable development; Effective removals; Isostructural; Particulate Matter; Quality factors; Reaction mixture; Removal efficiencies; Surface area; Synthesis conditions; Porosity English 2020 2020-07-01 10.1021/acsami.0c08881 바로가기 바로가기 바로가기 바로가기
Article Strain-Controlled Flexible Graphene/GaN/PDMS Sensors Based on the Piezotronic Effect Using simple graphene transfer and the laser lift-off process for a non-centrosymmetric GaN layer on a flexible polydimethylsiloxane (PDMS) substrate, the piezotronic effect by strain-induced current-voltage measurements at the two end points is studied. By inducing compressive strain on the flexible graphene/GaN/PDMS sensor, the Schottky barrier between the graphene and GaN/PDMS heterojunction can be electro-mechanically modulated by the piezotronic effect. It is observed that the flexible graphene/GaN/PDMS sensor is sensitive to various applied compressive and tensile strains in the positive/negative bias scans. The sensor is extremely sensitive to a compressive strain of -0.1% with a gauge factor of 13.48, which is 3.7 times higher than that of a standard metal strain gauge. Furthermore, the sharp response of the flexible graphene/GaN/PDMS sensor under the -0.1% compressive strain is also investigated. The results of this study herald the development of commercially viable large-scale flexible/wearable strain sensors based on the strain-controlled piezotronic effect in future investigations. Puneetha, Peddathimula; Mallem, Siva Pratap Reddy; Lee, Young-Woong; Shim, Jaesool Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Yeungnam Univ, Sch Mech Engn, Gyongsan 38541, South Korea; Yeungnam Univ, LED IT Fus Technol & Res Ctr, Gyongsan 38541, South Korea 56354594100; 55422639100; 56673030100; 16040548500 drmspreddy@knu.ac.kr;jshim@ynu.ac.kr; ACS APPLIED MATERIALS & INTERFACES ACS APPL MATER INTER 1944-8244 1944-8252 12 32 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 2.03 2025-06-25 56 54 flexible PDMS; non-centrosymmetric GaN layer; graphene layer; strain-induced; piezotronic effect SCHOTTKY DIODES; GRAPHENE; CHALLENGES; RAMAN; SKIN flexible PDMS; graphene layer; non-centrosymmetric GaN layer; piezotronic effect; strain-induced Gallium nitride; Graphene; Heterojunctions; III-V semiconductors; Polydimethylsiloxane; Schottky barrier diodes; Silicones; Strain gages; Compressive strain; Current voltage measurement; Laser lift-off; Non-centrosymmetric; Polydimethylsiloxane (PDMS) substrates; Positive/negative; Schottky barriers; Strain-controlled; Strain English 2020 2020-08-12 10.1021/acsami.0c06534 바로가기 바로가기 바로가기 바로가기
Article Surface Engineering of Low-Temperature Processed Mesoporous TiO2 via Oxygen Plasma for Flexible Perovskite Solar Cells A major problem in the application of mesoporous TiO2 as an electron transport layer for flexible perovskite solar cells is that a high-temperature sintering process is required to remove organic additives from the TiO2 layer. A facile oxygen plasma process is herein demonstrated to fabricate mesoporous-structured perovskite solar cells with significant photovoltaic performance at low temperatures. When the low-temperature processed TiO2 layer is modified via oxygen plasma, the organic additives in the TiO2 layer that hinder the charge transport process are successfully decomposed. The oxygen plasma treatment improves the wettability and infiltration of the perovskite layer and also passivates the oxygen vacancy related traps in TiO2. Hence, the oxygen plasma treatment evidently enhances charge extraction and transport, thereby improving photovoltaic performance and decreasing hysteresis. Nam, Jiyoon; Kim, Jae Ho; Kim, Chang Su; Kwon, Jung-Dae; Jo, Sungjin Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, Daegu 41566, South Korea; Korea Inst Mat Sci, Surface Technol Div, Chang Won 51508, Gyeongnam, South Korea 57191331045; 57215852650; 57201346735; 12804748400; 7101724027 sungjin@knu.ac.kr; ACS APPLIED MATERIALS & INTERFACES ACS APPL MATER INTER 1944-8244 1944-8252 12 11 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 1.65 2025-06-25 43 42 mesoporous TiO2; perovskite solar cell; low-temperature processed TiO2; oxygen plasma; flexible solar cell V HYSTERESIS; PERFORMANCE; EFFICIENT; FILMS flexible solar cell; lowerature processed TiO<sub>2</sub> ; mesoporous TiO<sub>2</sub> ; oxygen plasma; perovskite solar cell Additives; Cell engineering; Electron transport properties; Mesoporous materials; Oxygen; Oxygen vacancies; Perovskite; Plasma applications; Sintering; Solar power generation; Titanium dioxide; Charge transport process; Electron transport layers; Flexible solar cells; lowerature processed TiO2; Mesoporous TiO2; Oxygen plasma treatments; Oxygen plasmas; Photovoltaic performance; Perovskite solar cells English 2020 2020-03-18 10.1021/acsami.9b18660 바로가기 바로가기 바로가기 바로가기
Article Triamcinolone-Gold Nanoparticles Repolarize Synoviocytes and Macrophages in an Inflamed Synovium Understanding the crosstalk between synoviocytes and macrophages is very important for the development of strategies to regulate inflammatory responses in an inflamed synovium. Simultaneous regulation of the pro- and anti-inflammatory responses of synoviocytes and macrophages (repolarization) is critical for the treatment of arthritis. Thus, the immune regulatory functions of an ideal nanodrug should not only decrease the pro-inflammatory response but also effectively increase the anti-inflammatory response. In this study, crosstalk between synoviocytes and macrophages was found to be significantly involved in the activation and deactivation of inflammatory responses in the synovium. Interestingly, a developed triamcinolone-gold nanoparticle (Triam-AuNP) complex both decreased the pro-inflammatory responses and increased the anti-inflammatory responses of fibroblast-like synoviocytes (FLSs) and macrophages via repolarization of macrophages from the M1 to the M2 phenotype. In contrast, triamcinolone alone only decreased the pro-inflammatory responses of FLSs and macrophages without upregulating their anti-inflammatory responses. In vitro (human), ex vivo (human), and in vivo (mouse) analyses clearly indicated that Triam-AuNPs effectively regulated the expression of both pro- and anti-inflammatory cytokines in FLSs and effectively repolarized activity of macrophages in the inflamed synovium. Furthermore, Triam-AuNPs significantly promoted cartilage regeneration, whereas triamcinolone alone did not induce either FLS anti-inflammatory activity or macrophage repolarization. Park, Jun-Young; Kwon, Song; Kim, Sang-Hyun; Kang, Youn Joo; Khang, Dongwoo Gachon Univ, Dept Gachon Adv Inst Hlth Sci & Technol GAIHST, Incheon 21999, South Korea; Gachon Univ, Lee Gil Ya Canc & Diabet Inst, Incheon 21999, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu 41944, South Korea; Eulji Univ, Nowon Eulji Med Ctr, Dept Rehabil Med, Seoul 01830, South Korea; Gachon Univ, Lee Gil Ya Canc & Diabet Inst, Dept Gachon Adv Inst Hlth Sci & Technol GAIHST, Incheon 21999, South Korea; Gachon Univ, Coll Med, Dept Physiol, Incheon 21999, South Korea 57211684904; 57210259677; 57210450420; 24344325600; 26039177500 md52516@hanmail.net;dkhang@gachon.ac.kr; ACS APPLIED MATERIALS & INTERFACES ACS APPL MATER INTER 1944-8244 1944-8252 12 35 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2020 9.229 13.0 1.59 2025-06-25 47 52 arthritis; gold nanoparticles; synoviocytes; macrophages; repolarization COLLAGEN-INDUCED ARTHRITIS; MATRIX METALLOPROTEINASES; RHEUMATOID-ARTHRITIS; OSTEOARTHRITIS; INFLAMMATION; INJECTIONS; MEMBRANE; MMP-1; KNEE arthritis; gold nanoparticles; macrophages; repolarization; synoviocytes Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Survival; Cytokines; Down-Regulation; Gold; Humans; Macrophage Activation; Macrophages; Male; Metal Nanoparticles; Mice; Mice, Inbred DBA; Reactive Oxygen Species; Synoviocytes; Triamcinolone; Cell culture; Crosstalk; Gold nanoparticles; Metal nanoparticles; cytokine; gold; metal nanoparticle; reactive oxygen metabolite; triamcinolone; Anti-inflammatories; Anti-inflammatory activity; Anti-inflammatory response; Cartilage regeneration; Immune regulatory functions; Inflammatory response; Repolarization; Triamcinolone; animal; cell survival; chemistry; cytology; DBA mouse; down regulation; drug effect; experimental arthritis; human; macrophage; macrophage activation; male; metabolism; mouse; pathology; rheumatoid arthritis; synoviocyte; Macrophages English 2020 2020-09-02 10.1021/acsami.0c09842 바로가기 바로가기 바로가기 바로가기
Article Activatable red emitting fluorescent probe for rapid and sensitive detection of intracellular peroxynitrite Peroxynitrite (ONOO-), a highly reactive oxygen species generated by the reaction of nitric oxide and super-oxide radical anion, is involved in numerous physiological and pathological processes in the human body. To identify important pathogenic mechanisms, it is crucial to develop a reliable tool for detecting peroxynitrite in living systems. In the present study, a new difluoroboron beta-diketonate-based fluorescent probe for detecting exogenous and endogenous peroxynitrite in living systems was designed. The red emitting fluorophore can be synthesized in a simple three-step procedure. This probe reacts quickly and selectively with peroxynitrite and its detection limit is determined to be as low as 19.8 nM. It allows for clear imaging of peroxynitrite in RAW 264.7 cells and was successfully applied to visualize changes of intracellular peroxynitrite induced by reactive oxygen species inhibitors. This designed probe is an effective tool for investigating the physiological and pathological role of peroxynitrite in living cells. Kang, Seong Hee; Chung, Byung Yeoup; Park, Jung Eun; Jeon, Jongho; Park, Yong Dae Korea Atom Energy Res Inst, ARTI, Res Div Biotechnol, Jeongeup Si 56212, Jeollabuk Do, South Korea; Kyungpook Natl Univ, Sch Appl Chem Engn, Dept Appl Chem, Daegu 41566, South Korea 56402145200; 55500036900; 57210160353; 35082028100; 16425858100 jeonj@knu.ac.kr;ydpark@kaeri.re.kr; TALANTA TALANTA 0039-9140 1873-3573 217 SCIE CHEMISTRY, ANALYTICAL 2020 6.057 13.2 1.38 2025-06-25 23 25 Fluorescent probe; Activatable dye; Peroxynitrite; Rapid detection; Cell imaging NITRIC-OXIDE SYNTHASE; SELECTIVE DETECTION; FAR-RED; IN-VIVO; LIVE CELLS; MITOCHONDRIA; SUPEROXIDE; INHIBITION; OXIDATION; DESIGN Activatable dye; Cell imaging; Fluorescent probe; Peroxynitrite; Rapid detection Animals; Cells, Cultured; Fluorescent Dyes; Mice; Molecular Structure; Peroxynitrous Acid; RAW 264.7 Cells; Biological systems; Fluorescence; Nitric oxide; Oxygen; Physiology; Reactive oxygen species; fluorescent dye; peroxynitrous acid; Detection limits; Fluorescent probes; Living systems; Pathogenic mechanisms; Pathological process; Raw 264.7 cells; Sensitive detection; Superoxide radical anions; animal; cell culture; chemical structure; chemistry; mouse; RAW 264.7 cell line; synthesis; Probes English 2020 2020-09 10.1016/j.talanta.2020.121053 바로가기 바로가기 바로가기 바로가기
Article Critical heat flux (CHF) in pool boiling under static and rolling conditions Experimental investigations were attempted to simultaneously observe the vapor behaviors and critical heat flux under static and rolling conditions. From visualization results, vapor initiated, grew, and detached individually in a vertical direction from the static heated surfaces (at 10, 20, and 30 degrees). While under rolling motion, initiated vapor grew, and interacted with each other, resulting in forming a wider dry spot on the heated surface. Also, it was observed that the vapor drifted upward and stayed on the heated surface longer compared to under static condition. The faster the platform rolls, the longer the vapor stay on the heated surface, significantly decreasing the CHF. On the other hand, as the platform rolls slower (at high rolling period), CHF increases. CHF was decreased with increasing maximum rolling amplitude and inclination angle under both conditions (static and rolling). CHF under rolling conditions was noticed to be lower than under static condition except at maximum rolling amplitude of 10 degrees. The bubble departure frequency at a maximum rolling amplitude of 10 degrees was the highest among all of rolling amplitudes, thereby enhancing the CHF. These results indicate that rolling motion significantly affects vapor behaviors and CHF. (C) 2019 Korean Nuclear Society, Published by Elsevier Korea LLC. Tanjung, Elvira F.; Albdour, Samah A.; Jeong, Yeon Uk; Jo, Daeseong Kyungpook Natl Univ, Sch Mech Engn, 80 Daehak Ro, Daegu 702701, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, 80 Daehak Ro, Daegu 702701, South Korea ALBDOUR, SAMAH/AAR-9857-2021 57202612180; 57205234242; 35324325200; 16424303000 djo@knu.ac.kr; NUCLEAR ENGINEERING AND TECHNOLOGY NUCL ENG TECHNOL 1738-5733 52 3 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2020 2.341 13.2 0.63 2025-06-25 8 9 Critical heat flux; Vapor behaviors; Static condition; Rolling motion; Pool boiling OSCILLATING ACCELERATION FIELD; NATURAL CIRCULATION CHARACTERISTICS; RECTANGULAR CHANNEL; MARINE REACTOR; BUBBLE BEHAVIORS; PULSATING FLOW; MOTION; WATER; MECHANISM; NARROW Critical heat flux; Pool boiling; Rolling motion; Static condition; Vapor behaviors English 2020 2020-03 10.1016/j.net.2019.08.005 바로가기 바로가기 바로가기 바로가기
Article Experimental study of bubble flow behavior during flow instability under uniform and non-uniform transverse heat distribution Experiments are conducted to study bubble flow behavior during the instability of subcooled boiling under uniform and non-uniform transverse heating. The non-uniform heat distribution introduces non-uniform bubble generation and condensation rates on the heated surface, which is different from the uniform heating. These bubble generation and condensation characteristics introduce a non-uniform local pressure distribution in the transverse direction, which creates an extra non-uniform pressure on the flowing bubbles. Therefore, different bubble flow behavior can be observed between uniform and non-uniform heating conditions. In the uniform heating, bubble velocity fluctuations are low, and the bubbles travel straight along the axial direction. In the non-uniform heating, more fluctuation in the bubble velocity occurs at low mass flow rate and high subcooled inlet temperatures, and reverse flow is observed. Additionally, the bubbles show a zigzag trajectory when they pass through the channel, which indicates the existence of cross flow in the transverse direction. (C) 2020 Korean Nuclear Society, Published by Elsevier Korea LLC. Al-Yahia, Omar S.; Yoon, Ho Joon; Jo, Daeseong Khalifa Univ Sci & Technol, Emirates Nucl Technol Ctr, Abu Dhabi, U Arab Emirates; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehak Ro, Daegu 41566, South Korea Al-yahia, Omar/AAH-8536-2019 55788375900; 55221657300; 16424303000 djo@knu.ac.kr; NUCLEAR ENGINEERING AND TECHNOLOGY NUCL ENG TECHNOL 1738-5733 52 12 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2020 2.341 13.2 0.11 2025-06-25 5 6 Bubble flow behavior; Subcooled flow instability; Non-uniform heat distribution; Narrow rectangular channel NARROW RECTANGULAR CHANNEL; PRESSURE; UPFLOW; ONSET; ONB Bubble flow behavior; Narrow rectangular channel; Non-uniform heat distribution; Subcooled flow instability English 2020 2020-12 10.1016/j.net.2020.05.025 바로가기 바로가기 바로가기 바로가기
Article Highly sensitive voltammetric immunosensor for the detection of prostate specific antigen based on silver nanoprobe assisted graphene oxide modified screen printed carbon electrode In this work, we developed an effective voltammetric immunosensing platform for the sensitive detection of prostate specific antigen (PSA) utilizing a graphene oxide (GO) modified screen-printed carbon electrode (SPCE) hybridized with the ex-situ prepared silver nanoparticles (AgNPs) as a probe and signal transducer. The sensing platform comprises a direct-type immunoassay involving the selective interaction of PSA with anti-PSA. The surface morphology and analytical performance of the modified SPCE were characterized through relevant instrumentations. The changes in the voltammetric reduction current of AgNPs at 0.11 V in the sensor electrode was correlated to the PSA concentration. Under optimum conditions, the fabricated immunosensor exhibited a sensitive response to PSA with a limit of detection (LOD) of 0.27 ng mL(-1) and a dynamic calibration range of 0.75-100.0 ng mL(-1). We demonstrated that the participation of AgNPs along with GO modification contribute to the desired signal amplification and sensitive detection of PSA. It is anticipated that the proposed immunosensor can serve as a biomarker and potentially be utilized for the real sample quantification of PSA. Thunkhamrak, Chidkamon; Chuntib, Prakit; Ounnunkad, Kontad; Banet, Philippe; Aubert, Pierre-Henri; Saianand, Gopalan; Gopalan, Anantha-Iyengar; Jakmunee, Jaroon Chiang Mai Univ, Fac Sci, Dept Chem, Chiang Mai 50200, Thailand; Chiang Mai Univ, Fac Sci, Res Lab Analyt Instrument & Electrochem Innovat, Chiang Mai 50200, Thailand; Chiang Mai Univ, Fac Sci, Res Ctr Chem Dev Hlth Promoting Prod Northern Res, Chiang Mai 50200, Thailand; Chiang Mai Univ, Grad Sch, Chiang Mai 50200, Thailand; Minist Agr & Cooperat, Dept Agr, Agr Prod Sci Res & Dev Div, 50 Phahotyothin Rd, Bangkok 10900, Thailand; UCP, LPPI, EA 2528, 5 Mail Gay Lussac,Site Neuville, F-95000 Cergy Pontoise, France; Univ Newcastle, Fac Engn & Built Environm, Global Innovat Ctr Adv Nanomat, Callaghan, NSW 2308, Australia; Kyungpook Natl Univ, Daegyeong Reg Infrastruct Technol Dev Ctr, Daegu 41566, South Korea Ounnunkad, Kontad Suriya/O-9185-2018; Ounnunkad, Kontad/O-9185-2018; Gopalan, Saianand/J-6000-2019; Aubert, Pierre-Henri/C-1139-2013; Aubert, Pierre-Henri/ABF-1255-2020; Jakmunee, Jaroon/F-5032-2015 57194016220; 56717765700; 54891618900; 30367500300; 7006385593; 38362265400; 57191999779; 6701614625 jaroon.jakmunee@cmu.ac.th; TALANTA TALANTA 0039-9140 1873-3573 208 SCIE CHEMISTRY, ANALYTICAL 2020 6.057 13.2 3.7 2025-06-25 73 75 PSA; Electrochemical immunosensor; AgNPs probe; Voltammetric detection FREE ELECTROCHEMICAL IMMUNOSENSOR; LABEL-FREE; GOLD NANOPARTICLES; AU; CANCER; IMMUNOASSAY; FABRICATION; SYSTEM; FILM; PSA AgNPs probe; Electrochemical immunosensor; PSA; Voltammetric detection Carbon; Electrochemistry; Electrodes; Graphite; Humans; Immunoassay; Limit of Detection; Nanostructures; Printing; Prostate-Specific Antigen; Silver; Electrodes; Graphene; Immunosensors; Morphology; Probes; Silver nanoparticles; Surface morphology; Urology; Voltammetry; carbon; graphene oxide; graphite; nanomaterial; prostate specific antigen; silver; Analytical performance; Electrochemical immunosensors; Prostate specific antigen; Screen-printed carbon electrodes; Selective interaction; Silver nanoparticles (AgNps); Voltammetric detection; Voltammetric reduction; blood; chemistry; devices; electrochemistry; electrode; human; immunoassay; limit of detection; printing; Antigens English 2020 2020-02-01 10.1016/j.talanta.2019.120389 바로가기 바로가기 바로가기 바로가기
Article Indoor radon and thoron from building materials: Analysis of humidity, air exchange rate, and dose assessment Building materials contribute significantly to the indoor radon and thoron levels. Therefore, parameters that influence the exhalation rates of radon and thoron from building material need to be analyzed closely. As a preliminary study, the effects of humidity on exhalation rates were measured using a system with an accumulation chamber and RAD7 detector for Korean brick, Korean soil, and Indonesian brick. Resulting doses to a person who resides in a room constructed from the building materials were assessed by UNSCEAR method for different air exchange rates. The measurements have revealed that Korean brick exhaled the highest radon and thoron while Indonesian brick exhaled the lowest thoron. Results showed that for a typical low dense material, radon and thoron exhalation rate will increase until reached its maximum at a certain value of humidity and will remain saturated above it. Analysis on concentration and effective dose showed that radon is strongly affected by air exchange rate (ACH). This is showed by about 66 times decrease of radon dose from 0.00 h(-1) to those of 0.50 h(-1) ACH and decrease by a factor of 2 from 0.50 h(-1) to those of 0.80 h(-1). In case of thoron, the ACH doesn't have significant effects on effective dose. (c) 2020 Korean Nuclear Society, Published by Elsevier Korea LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Syuryavin, Ahmad Ciptadi; Park, Seongjin; Nirwono, Muttaqin Margo; Lee, Sang Hoon Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, Daegu 41566, South Korea; BAPETEN, Nucl Energy Regulatory Agcy, Jl Gajah Mada 8, Jakarta 10120, Indonesia; Radiat Sci Res Inst RSRI, Daehak Ro 80, Daegu 41566, South Korea Nirwono, Muttaqin Margo/D-1426-2017 hiyoiris@gmail.com; NUCLEAR ENGINEERING AND TECHNOLOGY NUCL ENG TECHNOL 1738-5733 52 10 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2020 2.341 13.2 30 Natural radioactivity; Indoor environment; Radon-thoron exhalation rate; Building material; Radiological risk METEOROLOGICAL PARAMETERS; EXHALATION; SOIL English 2020 2020-10 10.1016/j.net.2020.03.013 바로가기 바로가기 바로가기
Article Inhibition of streptococcal biofilm formation by Aronia by extracellular RNA degradation BACKGROUND The accumulation of oral bacterial biofilms is one of the primary etiological factors for oral diseases. Aronia melanocarpa extracts display general health benefits, including antimicrobial activities. This study evaluates the inhibitory effect of Aronia juice on oral streptococcal biofilm formation. RESULTS Exposure to 1/10-diluted Aronia juice for 1 min significantly decreased in vitro streptococcal biofilm formation (P < 0.001). No remarkable difference was noted in streptococcal growth by Aronia under the same conditions. Interestingly, 1 week of oral rinse with diluted Aronia juice led to significantly fewer salivary streptococcal colony-forming units (CFUs) relative to oral rinsing with tap water (P < 0.05). Furthermore, Aronia exerted an extracellular RNA-degrading effect, and RNase inhibitor alleviated Aronia-dependent streptococcal biofilm inhibition. CONCLUSION Aronia might inhibit initial biofilm formation by decomposing extracellular RNA, which plays an important role in bacterial biofilm formation. Our data suggest that oral rinsing with Aronia juice will aid in treating oral biofilm-dependent diseases easily and efficiently. (c) 2019 Society of Chemical Industry Lee, Heon-Jin; Oh, Su Young; Hong, Su-Hyung Kyungpook Natl Univ, Sch Dent, Dept Microbiol & Immunol, 2177 Dalgubeol Daero, Daegu 700472, South Korea 36462383000; 57204016703; 8691449100 hongsu@knu.ac.kr; JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE J SCI FOOD AGR 0022-5142 1097-0010 100 4 SCIE AGRICULTURE, MULTIDISCIPLINARY;CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY 2020 3.639 13.2 0.25 2025-06-25 3 4 Aronia; mutans streptococci; oral biofilm; oral rinse; RNA degradation ANTIMICROBIAL ACTIVITY; IN-VITRO; MELANOCARPA; CARIOGENICITY; MECHANISMS; BACTERIA; EFFICACY; MUTANS; FRUITS; CARIES Aronia; mutans streptococci; oral biofilm; oral rinse; RNA degradation Anti-Bacterial Agents; Biofilms; Photinia; Plant Extracts; RNA, Bacterial; Streptococcus; antiinfective agent; bacterial RNA; plant extract; biofilm; chemistry; drug effect; genetics; growth, development and aging; isolation and purification; metabolism; Photinia; physiology; Streptococcus English 2020 2020-03-15 10.1002/jsfa.10223 바로가기 바로가기 바로가기 바로가기
Article Selective adsorption of Cs⁺ by MXene (Ti3C2Tx) from model low-level radioactive wastewater This study explored whether MXene (Ti3C2Tx) could remove radioactive Cs+ from model nuclear wastewater. Various adsorption tests were performed and the physical aspects of the interaction were investigated. We varied the MXene dosage, Cs+ initial concentration, solution pH, solution temperature and exposure time. MXene adsorption exhibited very fast kinetics, based on the fact that equilibrium was achieved within 1 h. MXene exhibited an outstanding adsorption capacity (148 mg g(-1)) at adsorbent and adsorbate concentrations of 5 and 2 mg L-1, respectively, at neutral pH condition (i.e., pH 7). We explored Cs+ adsorption by MXene in the presence of four different ions (NaCl, KCl, CaCl2 and MgCl2) and three different organic acids (sodium oleate, oxalic acid, and citric acid). The Cs+ removal rate changed in the presence of these components; adsorption of Cs+ by MXene thus involved ion exchange, supported by both Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy. We confirmed that MXene was re-usable for at least four cycles. MXene is cost-effective and practical when used to adsorb radionuclides (e.g., Cs+) in nuclear wastewater. (C) 2019 Korean Nuclear Society, Published by Elsevier Korea LLC. Jun, Byung-Moon; Jang, Min; Park, Chang Min; Han, Jonghun; Yoon, Yeomin Univ South Carolina, Dept Civil & Environm Engn, 300 Main St, Columbia, SC 29208 USA; Kwangwoon Univ, Dept Environm Engn, 447-1 Wolgye Dong, Seoul, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Korea Army Acad Young Cheon, Dept Civil & Environm Engn, 495 Hogook Ro, Gyeongbuk 38900, South Korea ; Jang, Min/M-6690-2018; Jang, Min/J-2230-2012; Park, Chang Min/CAA-8506-2022; Jun, Byung-Moon/Y-2134-2019; Yoon, Yeomin/KDP-2253-2024 55326699900; 36762550700; 57209588953; 59803784200; 7402126688 phoenixvov@nate.com;yoony@cec.sc.edu; NUCLEAR ENGINEERING AND TECHNOLOGY NUCL ENG TECHNOL 1738-5733 52 6 SCIE NUCLEAR SCIENCE & TECHNOLOGY 2020 2.341 13.2 6.88 2025-06-25 89 103 Radioactive cesium; Mechanism; Adsorption; MXene AQUEOUS-SOLUTION; REMOVAL; CESIUM; CARBON; HEXACYANOFERRATE; NANOMATERIALS; PERFORMANCE; NANOSHEETS; MECHANISM; STRONTIUM Adsorption; Mechanism; MXene; Radioactive cesium English 2020 2020-06 10.1016/j.net.2019.11.020 바로가기 바로가기 바로가기 바로가기
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