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| ○ | ○ | Article | Rapid biodegradation of chlorpyrifos by plant growth-promoting psychrophilic Shewanella sp. BT05: An eco-friendly approach to clean up pesticide-contaminated environment | The present study explores the rapid chlopyrifos (CPs) biodegradation potential of plant growth promoting (PGP) psychrophilic bacteria isolated from brackish water by enrichment culture technique. Based on biochemical tests and 16 S rDNA sequencing the isolate was identified as Shewanella sp. The isolate Shewanella BT05 showed significant growth rate in various concentrations of (10-50 mg/L) CPs. The isolate produced plant growth promoting factors, IAA (20.8 +/- 1.2 and 15.4 +/- 1.0 ug/mL) and siderophores (60.67 +/- 1.2 and 57.5 +/- 0.9%) in the absence and presence of CPs. Further, the isolate BT05 solublized phosphate (16.5 +/- 1.0 and 12.0 +/- 1.0 mm in size respectively), and produce hydrogen cyanide (excellent and moderate) in the presence and absence of CPs. The isolate BT05 degraded 94.3, 91.8, 87.9, 82.6, and 80.5% of CPs at 10, 20, 30, 40, and 50 mg/L, respectively, within 24 h. Further, the media conditions were optimized for enhanced CPs removal and observed 93% removal in the presence of 3.5% glucose in pH 7.0 at 32.5 degrees C. Fourier-transform infrared spectroscopy and high-performance liquid chromatography results indicated the role for Shewanella BT05 in the biomineralization of CPs. The results suggested the isolate BT05 could be used for CPs removal as well as PGP activity in contaminated soil. (C) 2020 Elsevier Ltd. All rights reserved. | Govarthanan, M.; Ameen, Fuad; Kamala-Kannan, S.; Selvankumar, T.; Almansob, A.; Alwakeel, S. S.; Kim, Woong | Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; King Saud Univ, Coll Sci, Dept Bot & Microbiol, Riyadh 11451, Saudi Arabia; Chonbuk Natl Univ, Coll Environm & Bioresource Sci, Div Biotechnol, Iksan 54596, South Korea; Mahendra Arts & Sci Coll Autonomous, PG & Res Dept Biotechnol, Namakkal 637501, Tamil Nadu, India; Princess Nourah Bint Abdulrahman Univ, Coll Sci, Dept Biol, Riyadh, Saudi Arabia | Govarthanan, Muthusamy/C-1491-2014; Muthusamy, Govarthanan/C-1491-2014; Alwakeel, Suaad/GSM-7657-2022; Almansob, Abobakr/JUU-2517-2023; Selvankumar, Thangaswamy/W-1639-2019; Ameen, Fuad/N-8881-2017; Kamala-Kannan, Seralathan/JZT-7242-2024 | 54881927600; 56664337800; 55664148800; 24485017700; 57209109324; 24174257600; 55581636400 | gova.muthu@gmail.com;elshine@knu.ac.kr; | CHEMOSPHERE | CHEMOSPHERE | 0045-6535 | 1879-1298 | 247 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 7.086 | 10.8 | 2.05 | 2025-06-25 | 51 | 59 | Biodegradation; Chlorpyrifos; Pesticide; Plant growth promoting activity; HPLC | DEGRADATION; STRAIN; SOIL; BACTERIA; REMOVAL | Biodegradation; Chlorpyrifos; HPLC; Pesticide; Plant growth promoting activity | Biodegradation, Environmental; Chlorpyrifos; Insecticides; Pesticides; Phosphates; Plant Development; Plants; Shewanella; Siderophores; Soil Microbiology; Soil Pollutants; Shewanella; Shewanella sp.; Bacteria; Biomineralization; Fourier transform infrared spectroscopy; High performance liquid chromatography; Pesticides; Soil pollution; brackish water; chlorpyrifos; DNA 16S; glucose; growth promotor; hydrogen cyanide; indoleacetic acid; pesticide; phosphate; siderophore; chlorpyrifos; insecticide; pesticide; phosphate; Biodegradation potentials; Chlorpyrifos; Contaminated environment; Contaminated soils; Enrichment culture; HPLC; Plant growth promoting; Psychrophilic bacteria; bacterium; biodegradation; chlorpyrifos; cleanup; growth regulator; liquid chromatography; pesticide; pollutant removal; Article; bacterial strain; bacterium isolate; biochemical analysis; biomineralization; bioremediation; DNA sequence; enrichment culture; Fourier transform infrared spectroscopy; growth rate; high performance liquid chromatography; in vitro study; nonhuman; pH; plant growth; psychrophilic bacterium; Shewanella; solubilization; waste component removal; waste water management; water pollution; isolation and purification; metabolism; microbiology; plant; plant development; Shewanella; soil pollutant; Biodegradation | English | 2020 | 2020-05 | 10.1016/j.chemosphere.2020.125948 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Reduced graphene oxide-TiO2/sodium alginate 3-dimensional structure aerogel for enhanced photocatalytic degradation of ibuprofen and sulfamethoxazole | In this study, graphene oxide and titanium dioxide in combination with sodium alginate were used to synthesize the reduced graphene oxide-TiO2 /sodium alginate (RGOT/SA) aerogel. The potential of RGOT/ SA aerogel was evaluated for the photocatalytic degradation of ibuprofen and sulfamethoxazole and was compared with that of bare titanium dioxide nanoparticles. More than 99% removal of both the contaminants was obtained within 45-90 min by using the RGOT/SA aerogel under UV-A light. Mineralization of both the pollutants was also higher in case of RGOT/SA aerogel as compared to bare TiO2 nanoparticles. The optimal mass ratio of TiO2 nanoparticles with respect to graphene oxide was 2:1 in RGOT/SA aerogel in the presence of 1 wt% sodium alginate solution. High photodegradation of Ibuprofen was observed at neutral pH and acidic to neutral pH was found suitable for the photodegradation of sulfamethoxazole. Three-dimensional interconnected macroporous assembly, large surface area for settling TiO2 nanoparticles, efficient charge partitioning, and enhanced physical and chemical adsorption of ibuprofen and sulfamethoxazole on the surface of RGOT/SA aerogel were the significant characteristics of RGOT/SA aerogels. Moreover, ease of separation and recyclability of the RGOT/SA aerogel could further save the extra energy used to separate nanoparticles from the effluent. (C) 2020 Elsevier Ltd. All rights reserved. | Nawaz, Mohsin; Khan, Alamgir A.; Hussain, Abid; Jang, Jiseon; Jung, Hee-Young; Lee, Dae Sung | Muhammad Nawaz Shareef Univ Agr, Dept Agr Engn, Old Shujabad Rd, Multan 60000, Pakistan; Muhammad Nawaz Shareef Univ Agr, Dept Soil & Environm Sci, Old Shujabad Rd, Multan 60000, Pakistan; Korea Radioact Waste Agcy, R&D Inst Radioact Wastes, 174 Gajeong Ro, Daejeon 34129, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea | HUSSAIN, ABID/I-6445-2019 | 55235830600; 57202925398; 57216860861; 56611137400; 7403029383; 55568524907 | daesung@knu.ac.kr; | CHEMOSPHERE | CHEMOSPHERE | 0045-6535 | 1879-1298 | 261 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 7.086 | 10.8 | 4.16 | 2025-06-25 | 106 | 112 | Graphene oxide; Ibuprofen; Sodium alginate; Sulfamethoxazole; Titanium dioxide; Photodegradation | WASTE-WATER; TRANSFORMATION PRODUCTS; TIO2-GRAPHENE HYDROGEL; ANTIBACTERIAL ACTIVITY; TITANIUM-DIOXIDE; TIO2; COMPOSITE; PHOTODEGRADATION; NANOCOMPOSITE; IDENTIFICATION | Graphene oxide; Ibuprofen; Photodegradation; Sodium alginate; Sulfamethoxazole; Titanium dioxide | Adsorption; Alginates; Catalysis; Graphite; Hydrogen-Ion Concentration; Ibuprofen; Nanoparticles; Photolysis; Sulfamethoxazole; Titanium; Ultraviolet Rays; Graphene; Nanoparticles; Oxide minerals; Reduced Graphene Oxide; Sodium; Sodium alginate; TiO2 nanoparticles; Titanium dioxide; alginic acid; gel; graphene oxide; ibuprofen; sulfamethoxazole; titanium dioxide nanoparticle; alginic acid; graphene oxide; graphite; ibuprofen; nanoparticle; sulfamethoxazole; titanium; titanium dioxide; 3-dimensional structures; Alginate solutions; Chemical adsorption; Large surface area; Optimal mass ratio; Photo catalytic degradation; Recyclability; Sulfamethoxazole; adsorption; alginate; catalyst; drug; gel; nanoparticle; photochemistry; photodegradation; separation; sodium; surface area; titanium; adsorption; Article; chemical structure; controlled study; effluent; mass; mineralization; photocatalysis; photodegradation; physical chemistry; reduction (chemistry); surface area; catalysis; chemistry; pH; photolysis; ultraviolet radiation; Aerogels | English | 2020 | 2020-12 | 10.1016/j.chemosphere.2020.127702 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Removal of sulfadiazine and ciprofloxacin by clays and manganese oxides: Coupled sorption-oxidation kinetic model | Sorption onto clays (montmorillonite and kaolinite), oxidation and sorption by manganese oxides (synthesized MnO and natural MnO), and coupled sorption-oxidation experiments were conducted for the removal of antibiotics sulfadiazine (SDZ) and ciprofloxacin (CIP) at pH 5 and 8. Individual sorption and oxidation modelling were carried out using the first-order kinetic model. A coupled sorption -oxidation kinetic model was developed to predict the simultaneous sorption and oxidation process. The coupled sorption-oxidation enhanced the antibiotic sorption, with the first-order sorption rate constants in the simultaneous presence of clays and manganese oxides (ksorp) being higher than those with clays only (k(sorp)(0)). In contrast, a depression was observed; the first-order oxidation and sorption combination rate constants in the simultaneous presence of manganese oxides and clays (k(Mno)) were lower than those with manganese oxides only (k(MnO)(0)). In the coupled sorption-oxidation reaction, 13.5 -62.5% of SDZ and CIP removal was attributed to the sorption. The SDZ and CIP species distributions at pH 5 affected the coupled sorption and oxidation systems more than those at pH 8. The best removal efficiency was achieved by the montmorillonite-synthesized MnO combination, mainly due to the higher surface area (A(BET)) and pore size of montmorillonite and synthesized MnO combination compared to other clays and manganese oxides combinations. (C) 2020 Elsevier Ltd. All rights reserved. | Septian, Ardie; Shin, Won Sik | Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, Daegu 41566, South Korea | Septian, Ardie/HGB-8696-2022 | 57201503612; 23019870800 | wshin@knu.ac.kr; | CHEMOSPHERE | CHEMOSPHERE | 0045-6535 | 1879-1298 | 250 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 7.086 | 10.8 | 0.47 | 2025-06-25 | 14 | 13 | Coupled sorption-oxidation; Kaolinite; Montmorillonite; Natural MnO; Synthesized MnO | MONTMORILLONITE; ANTIBIOTICS; SOIL; DESORPTION; MECHANISMS; ADSORPTION; BEHAVIOR; ZEOLITE; SURFACE; STATE | Coupled sorption–oxidation; Kaolinite; Montmorillonite; Natural MnO; Synthesized MnO | Adsorption; Anti-Bacterial Agents; Bentonite; Ciprofloxacin; Clay; Environmental Restoration and Remediation; Kaolin; Kinetics; Manganese; Manganese Compounds; Models, Chemical; Oxidation-Reduction; Oxides; Sulfadiazine; Antibiotics; Clay minerals; Kaolinite; Kinetic parameters; Kinetic theory; Manganese oxide; Oxidation; Oxides; Pore size; Rate constants; ciprofloxacin; manganese oxide; montmorillonite; sulfadiazine; antiinfective agent; bentonite; ciprofloxacin; kaolin; manganese; manganese derivative; manganese oxide; oxide; sulfadiazine; First-order kinetic models; Natural MnO; Oxidation kinetic models; Oxidation process; Oxidation reactions; Removal efficiencies; Species distributions; Synthesized MnO; antibiotics; chemical compound; kaolinite; manganese oxide; numerical model; oxidation; pollutant removal; sorption; toxin; Article; oxidation; pH; waste component removal; adsorption; chemical model; chemistry; clay; ecosystem restoration; kinetics; oxidation reduction reaction; procedures; Sorption | English | 2020 | 2020-07 | 10.1016/j.chemosphere.2020.126251 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Selected advanced water treatment technologies for perfluoroalkyl and polyfluoroalkyl substances: A review | Numerous perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been widely found in both wastewater effluent and drinking water worldwide; thus, these chemicals have become a global issue as emerging organic contaminants. Aliphatic PFASs with saturated carbon-fluorine bonds appear to be incompletely removed during conventional chemical/physical (coagulation, flocculation, sedimentation, and filtration) and biological (activated sludge) treatment processes. However, they can be effectively removed by advanced treatment technologies such as sorption, membranes, and oxidation. Thus, it is essential to understand the removal mechanisms of various PFASs during these advanced treatment processes, in particular because the physicochemical characteristics of various PFASs impose difficult challenges regarding determining the transport and fate of these compounds in aqueous solution. Several review studies have been conducted to evaluate the removal of PFASs in various drinking water treatment and environmental remediation processes. However, to the best of our knowledge, very little information is still available on the effects of water quality conditions on the removal of PFASs. Therefore, in this study, we comprehensively summarize the recent state of knowledge of selected advanced water treatment technologies (sorption, membrane, and oxidation) for the removal of PFASs under different water quality conditions (e.g., pH, temperature, background ions, natural organic matter, and solute concentration). | Banks, Danny; Jun, Byung-Moon; Heo, Jiyong; Her, Namguk; Park, Chang Min; Yoon, Yeomin | Univ South Carolina, Dept Civil & Environm Engn, 300 Main St, Columbia, SC 29208 USA; Korea Army Acad Young Cheon, Dept Civil & Environm Engn, 495 Hogook Ro, Young Cheon 38900, Gyeongbuk, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea | ; Park, Chang Min/CAA-8506-2022; Yoon, Yeomin/KDP-2253-2024; Jun, Byung-Moon/Y-2134-2019 | 57210411653; 55326699900; 42461338400; 6701721727; 57209588953; 7402126688 | cmpark@knu.ac.kr;yoony@cec.sc.edu; | SEPARATION AND PURIFICATION TECHNOLOGY | SEP PURIF TECHNOL | 1383-5866 | 1873-3794 | 231 | SCIE | ENGINEERING, CHEMICAL | 2020 | 7.312 | 10.8 | 1.79 | 2025-06-25 | 102 | 106 | PFASs; Sorption; Membrane; Photocatalysis; Sonication; Water treatment | PERFLUOROOCTANE SULFONATE PFOS; ENDOCRINE DISRUPTING COMPOUNDS; NATURAL ORGANIC-MATTER; GRANULAR ACTIVATED CARBON; WASTE-WATER; PERFLUORINATED COMPOUNDS; SONOCHEMICAL DEGRADATION; DRINKING-WATER; REVERSE-OSMOSIS; PHOTOCATALYTIC DECOMPOSITION | Membrane; PFASs; Photocatalysis; Sonication; Sorption; Water treatment | Chemical water treatment; Effluents; Membranes; Organic chemicals; Photocatalysis; Potable water; Sonication; Sorption; Water quality; Water treatment; Emerging organic contaminants; Environmental remediation; Natural organic matters; PFASs; Physicochemical characteristics; Polyfluoroalkyl substances; Solute concentrations; Water treatment technologies; Chemicals removal (water treatment) | English | 2020 | 2020-01-16 | 10.1016/j.seppur.2019.115929 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Significance of allochthonous brackish water Halomonas sp. on biodegradation of low and high molecular weight polycyclic aromatic hydrocarbons | The present study is aimed to isolate and identify polycyclic aromatic hydrocarbons (PAHs) degrading bacteria from brackish water and to assess the biodegradation efficiency against low and high molecular weight PAHs. Among 15 isolates, the isolate designated as RM effectively degraded 100 mg/L of phenanthrene (Phe) (67.0%), pyrene (Pyr) (63.0%), naphthalene (NaP) (60.0%), and benzo [a]pyrene (BaP) (58.0%) after 7 days of incubation. Carbon sources, pH, and salinity of the culture medium were optimized to enhance the growth and PAHs biodegradation of the isolate RM. Sucrose was found to be an excellent carbon source to enhance PAHs biodegradation (Phe, 75.0; Pyr, 68.5; NaP, 62.5; and BaP, 59.5%). Furthermore, the isolate showed enhanced degradation at pH 7.0 and 4% salinity. The isolate RM was identified as Halomonas sp. based on partial 16S rDNA gene sequence analysis. The results indicated that the isolate RM (i.e., Halomonas sp.) has the potential to be used in remediation of oil spills in the marine ecosystem. (C) 2019 Elsevier Ltd. All rights reserved. | Govarthanan, M.; Khalifa, Ashraf Yz; Kamala-Kannan, S.; Srinivasan, P.; Selvankumar, T.; Selvam, K.; Kim, Woong | Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; King Faisal Univ, Coll Sci, Biol Sci Dept, Al Hasa, Saudi Arabia; Univ Beni Suef, Fac Sci, Bot & Microbiol Dept, Bani Suwayf, Egypt; Mahendra Arts & Sci Coll Autonomous, PG & Res Dept Biotechnol, Namakkal 637501, Tamil Nadu, India; Chonbuk Natl Univ, Coll Environm & Bioresource Sci, Div Biotechnol, Iksan 54596, South Korea | ; Muthusamy, Govarthanan/C-1491-2014; Khalifa, Ashraf/H-9127-2016; Selvam, Kandasamy/AAN-5860-2020; Selvankumar, Thangaswamy/W-1639-2019; Khalifa, Ashraf/GVT-4178-2022; Govarthanan, Muthusamy/C-1491-2014 | 54881927600; 55736708600; 55664148800; 57190217427; 24485017700; 57197362853; 55581636400 | gova.muthu@gmail.com;elshine@knu.ac.kr; | CHEMOSPHERE | CHEMOSPHERE | 0045-6535 | 1879-1298 | 243 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 7.086 | 10.8 | 3.28 | 2025-06-25 | 69 | 78 | Biodegradation; Halomonas sp.; Phenanthrene; Phyrene; Salinity | DEGRADATION; PAHS; PHENANTHRENE; SOIL; BIOREMEDIATION; IDENTIFICATION; BACTERIA | Biodegradation; Halomonas sp.; Phenanthrene; Phyrene; Salinity | Bacteria; Benzo(a)pyrene; Biodegradation, Environmental; Ecosystem; Halomonas; Molecular Weight; Naphthalenes; Polycyclic Aromatic Hydrocarbons; Pyrenes; Saline Waters; Halomonas; Anthracene; Barium compounds; Carbon; Ecosystems; Marine pollution; Mineral oils; Molecular weight; Naphthalene; Oil spills; Pyrene; Sodium compounds; benzo[a]pyrene; brackish water; DNA 16S; naphthalene; phenanthrene; polycyclic aromatic hydrocarbon; pyrene; sucrose; naphthalene derivative; polycyclic aromatic hydrocarbon; pyrene derivative; salt water; Biodegradation efficiency; Gene sequence analysis; Halomonas sp; High molecular weight; Phenanthrene; Phyrene; Polycyclic aromatic hydrocarbons (PAHS); Salinity; allochthon; bacterium; biodegradation; brackish water; genetic analysis; molecular analysis; naphthalene; optimization; PAH; phenanthrene; pyrene; salinity; Article; bacterium isolation; biodegradation; carbon source; comparative study; controlled study; enzyme activity; gene sequence; Halomonas; marine environment; nonhuman; oil spill; optical density; pH; phylogenetic tree; salinity; bacterium; bioremediation; ecosystem; Halomonas; isolation and purification; metabolism; molecular weight; Biodegradation | English | 2020 | 2020-03 | 10.1016/j.chemosphere.2019.125389 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Tracing the Anti-Inflammatory Mechanism/Triggers of d-Allulose: A Profile Study of Microbiome Composition and mRNA Expression in Diet-Induced Obese Mice | Scope The results of recent studies on d-allulose intervention in high-fat diet (HFD)-fed mice suggest that d-allulose has a substantial impact on obesity. In addition, several studies have uncovered bacterial candidates among the gut microbiota associated with obesity and inflammation in mice. To identify the d-allulose-attenuated genes related to the inflammation-associated bacterial candidates, two types of statistical analyses are performed. Methods and results Using liver and epididymal fat tissues, genes with expression levels that recovered from HFD-induced dysregulation are identified through differentially expressed gene (DEG) analysis. Finally, correlation-based network analysis between the diet, microbes, and the candidates identified from DEG analysis reveal 20 genes that showed anti-obesogenic patterns and associations with Lactobacillus and Coprococcus, which are representative bacterial candidates associated with inflammation and obesity. Conclusion The results of the present study suggest that d-allulose closely interacts with the candidate genes and microbes to alleviate weight gain and inflammation, partly via down regulation of Gm12250 expression in multiple tissues and increases the Lactobacillus and Coprococcus in gut microbiota composition. | Han, Youngji; Yoon, Joon; Choi, Myung-Sook | Kyungpook Natl Univ, Dept Food Sci & Nutr, 1370 San Kyuk Dong Puk Ku, Daegu 702701, South Korea; Kyungpook Natl Univ, Ctr Food & Nutr Genom Res, 1370 San Kyuk Dong Puk Ku, Daegu 702701, South Korea; Harvard Univ TH Chan Sch Publ Hlth, 655 Huntington Ave, Boston, MA 02115 USA | 57206914262; 56580912000; 7402093877 | mschoi@knu.ac.kr; | MOLECULAR NUTRITION & FOOD RESEARCH | MOL NUTR FOOD RES | 1613-4125 | 1613-4133 | 64 | 5 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2020 | 5.82 | 10.8 | 1.82 | 2025-06-25 | 34 | 35 | d-allulose; inflammation; mRNA sequencing; pyrosequencing | NECROSIS-FACTOR-ALPHA; GENE-EXPRESSION; GUT MICROBIOTA; METABOLIC SYNDROME; INFLAMMATION; VALIDATION; DYSBIOSIS; FRUCTOSE | d-allulose; inflammation; mRNA sequencing; pyrosequencing | Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Diet, High-Fat; Dietary Supplements; Fructose; Gastrointestinal Microbiome; Gene Expression Regulation; Male; Mice, Inbred C57BL; Mice, Obese; Obesity; antiobesity agent; fructose; nonsteroid antiinflammatory agent; psicose; animal; C57BL mouse; dietary supplement; drug effect; gene expression regulation; genetics; intestine flora; lipid diet; male; microbiology; mouse mutant; obesity; physiology | English | 2020 | 2020-03 | 10.1002/mnfr.201900982 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Ultrasound-assisted Ti3C2Tx MXene adsorption of dyes: Removal performance and mechanism analyses via dynamic light scattering | Herein, ultrasonication (US)-assisted novel nanomaterial Ti3C2Tx MXene was utilized as a selective adsorbent for treatment of synthetic dyes in model wastewater. Two types of US frequencies, 28 and 580 kHz, were applied to disperse MXene to evaluate the feasibility of US-assisted MXene for wastewater treatment. The physico-chemical properties of MXene after US were characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and zeta potential. According to FTIR and XPS, 28 kHz US-assisted MXene had a greater amount of oxygenated functional groups and dispersion compared to 580 kHz US-assisted and pristine MXene. Subsequently, US-assisted MXene was utilized as an adsorbent for the removal of positively charged methylene blue (MB) and negatively charged methyl orange. Both 28 and 580 kHz US-assisted MXene showed better adsorption performance for only MB compared to stirring-assisted MXene based on kinetics, isotherms, and several water chemistry factors including solution pH, temperature, ionic strength, and humic acid. Advantages of US-assisted MXene for water treatment are its fast kinetics at low dose and high selectivity for positively charged target compounds (i.e., MB). The main adsorption mechanism between MXene and MB was electrostatic interaction (attraction); however, physical properties (i.e., aggregation kinetics and hydrodynamic diameter), measured via dynamic light scattering, were also found to be critical factors in controlling the adsorption performance of the system. Lastly, US-assisted MXene exhibited a high regeneration property, based on 4th adsorption-desorption cycles. (C) 2020 Elsevier Ltd. All rights reserved. | Jun, Byung-Moon; Kim, Sewoon; Rho, Hojung; Park, Chang Min; Yoon, Yeomin | Univ South Carolina, Dept Civil & Environm Engn, 300 Main St, Columbia, SC 29208 USA; Arizona State Univ, Sch Sustainable Engn & Built Environm, Nanosyst Engn Res Ctr Nanotechnol Enabled Water T, Tempe, AZ 85287 USA; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea | ; Jun, Byung-Moon/Y-2134-2019; Park, Chang Min/CAA-8506-2022; Rho, Hojung/AAZ-5517-2020; Yoon, Yeomin/KDP-2253-2024 | 55326699900; 57201422323; 57196479406; 57209588953; 7402126688 | cmpark@knu.ac.kr;yoony@cec.sc.edu; | CHEMOSPHERE | CHEMOSPHERE | 0045-6535 | 1879-1298 | 254 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 7.086 | 10.8 | 4.98 | 2025-06-25 | 121 | 129 | Ultrasound-assisted adsorption; Dyes; MXene; Dynamic light scattering | ENDOCRINE-DISRUPTING COMPOUNDS; WASTE-WATER; MOFS; NANOMATERIALS; PB(II); CARBON; ACID | Dyes; Dynamic light scattering; MXene; Ultrasound-assisted adsorption | Adsorption; Azo Compounds; Coloring Agents; Dynamic Light Scattering; Kinetics; Methylene Blue; Spectroscopy, Fourier Transform Infrared; Titanium; Waste Water; Water Pollutants, Chemical; Water Purification; Adsorption; Aromatic compounds; Azo dyes; Dynamic light scattering; Ionic strength; Kinetics; Stripping (dyes); Ultrasonics; Wastewater treatment; Water treatment; X ray photoelectron spectroscopy; adsorbent; dye; humic acid; ion; methyl orange; methylene blue; titanium; water; azo compound; coloring agent; titanium; Adsorption mechanism; Adsorption performance; Adsorption-desorption cycles; Aggregation kinetics; Hydrodynamic diameter; Regeneration properties; Removal performance; Selective adsorbents; adsorption; dispersion; dye; light scattering; nanomaterial; performance assessment; pollutant removal; reaction kinetics; ultrasonics; wastewater treatment; water chemistry; adsorption; Article; desorption; dispersion; Fourier transform infrared spectroscopy; hydrodynamics; ionic strength; pH; photon correlation spectroscopy; static electricity; surface charge; temperature; thermodynamics; waste water management; water treatment; X ray photoemission spectroscopy; zeta potential; adsorption; chemistry; infrared spectroscopy; kinetics; photon correlation spectroscopy; procedures; waste water; water management; water pollutant; Fourier transform infrared spectroscopy | English | 2020 | 2020-09 | 10.1016/j.chemosphere.2020.126827 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A novel AIEgen-based probe for detecting cysteine in lipid droplets | A smart fluorescent probe DPAS-Cys has been rationally designed based on a typical AIEgen DPAS and an acrylate moiety. The probe DPAS-Cys not only can be used for the detection of cysteine (Cys) selectively with large Stokes shift (200 nm) and relatively low detection limit (2.4 mu M), but also shows lipid droplets (LDs) targeting property. The response mechanism for Cys was carefully verified. Importantly, due to the aggregation-induced emission characteristic, the introduction of considerable percentage of traditional organic solvent is avoidable, which makes it suitable for bioimaging in physiological systems. In addition, the confocal fluorescence imaging demonstrates that DPAS-Cys is able to detect Cys in LDs of different cell lines with universality. Our study opens a new avenue to understand the importance of LDs in biosystem, for which the gap between the essential biothiol Cys and the energy storage organelle LDs was bridged for the first time. (C) 2020 Elsevier B.V. All rights reserved. | Cheng, Wei; Xue, Xuqi; Zhang, Fang; Zhang, Baoxin; Li, Taihan; Peng, Liang; Cho, Dong-Hyung; Chen, Hongli; Fang, Jianguo; Chen, Xingguo | Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China; Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Peoples R China; Lanzhou Univ, Coll Basic Med Sci, Lanzhou 730000, Peoples R China; Kyungpook Natl Univ, Sch Life Sci, Daegu 41566, South Korea | ; Luo, Dongliang/Q-9637-2016; Choi, Hye Rin/JDV-9065-2023; Fang, Jianguo/K-8058-2016; Zhang, Fang/AAB-2115-2019 | 57212413037; 57217684672; 57216716219; 56026398800; 57217687893; 56763241600; 35093684400; 8090970600; 23027231500; 35184832100 | hlchen@lzu.edu.cn; | ANALYTICA CHIMICA ACTA | ANAL CHIM ACTA | 0003-2670 | 1873-4324 | 1127 | SCIE | CHEMISTRY, ANALYTICAL | 2020 | 6.558 | 10.9 | 1.41 | 2025-06-25 | 33 | 34 | Aggregation-induced emission; Cysteine detection; Cell imaging; Fluorescent probe; Lipid droplets | HIGHLY SELECTIVE DETECTION; OFF-ON PROBE; FLUORESCENT-PROBE; GLUTATHIONE; HOMOCYSTEINE; CONJUGATE; EMISSION; SENSOR; CYS; GSH | Aggregation-induced emission; Cell imaging; Cysteine detection; Fluorescent probe; Lipid droplets | Cysteine; Fluorescent Dyes; HeLa Cells; Humans; Lipid Droplets; Microscopy, Fluorescence; Amino acids; Cell culture; Cell proliferation; Drops; Fluorescence imaging; cysteine; fat droplet; cysteine; fluorescent dye; Aggregation-induced emissions; Confocal fluorescence imaging; Fluorescent probes; Lipid droplets; Low detection limit; Physiological systems; Response mechanisms; Stokes shift; Article; cell organelle; column chromatography; confocal microscopy; controlled study; fluorescence imaging; high performance liquid chromatography; human; human cell; hydrophilicity; lethargy; limit of detection; mass spectrometry; priority journal; protein metabolism; protein modification; protein structure; protein synthesis; proton transport; fluorescence microscopy; HeLa cell line; Probes | English | 2020 | 2020-08-29 | 10.1016/j.aca.2020.05.074 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | An accurate and dynamic predictive model for a smart M-Health system using machine learning | Nowadays, new highly-developed technologies are changing traditional processes related to medical and healthcare systems. Emerging Mobile Health (M-Health) systems are examples of novel technologies based on advanced data communication, deep learning, artificial intelligence, cloud computing, big data, and other machine learning methods. Data are collected from sensor nodes and forwarded to local databases through new technologies that enable cellular networks and then store the information in cloud storage systems. From cloud computing services or medical centres, the data are collected for further analysis. Furthermore, machine learning techniques are being used for accurate prediction of disease analysis and for purposes of classification. This paper presents a detailed overview of M-Health systems, their model and architecture, technologies and applications and also discusses statistical and machine learning approaches. We also propose a secure Androidbased architecture to collect patient data, a reliable cloud-based model for data storage. Finally, a predictive model able to classify cardiovascular diseases according to their seriousness will be discussed. Moreover, the proposed prediction model has been compared with existing models in terms of accuracy, sensitivity, and specificity. The experimental results show encouraging results in terms of the proposed predictive model for an M-Health system. (C) 2020 Elsevier Inc. All rights reserved. | Qureshi, Kashif Naseer; Din, Sadia; Jeon, Gwanggil; Piccialli, Francesco | Bahria Univ, Dept Comp Sci, Islamabad, Pakistan; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Xidian Univ, Sch Elect Engn, Xian 710071, Peoples R China; Incheon Natl Univ, Dept Embedded Syst Engn, Incheon 22012, South Korea; Univ Naples Federico II, Dept Math & Applicat R Caccioppoli, Naples, Italy | ; Qureshi, Kashif/AAJ-1052-2020; Din, Sadia/ADU-4679-2022; Piccialli, Francesco/ABC-2457-2020 | 55781386200; 57188997144; 15022497800; 42762051900 | ggjeon@gmail.com;francesco.piccialli@unina.it; | INFORMATION SCIENCES | INFORM SCIENCES | 0020-0255 | 1872-6291 | 538 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS | 2020 | 6.795 | 10.9 | 3.17 | 2025-06-25 | 52 | 76 | Machine learning; Predictive; Models; M-Health; Classification; SVM; Decision tree; Accuracy | BIG DATA; FRAMEWORK; SENSORS | Accuracy; Classification; Decision tree; M-Health; Machine learning; Models; Predictive; SVM | Cloud computing; Decision trees; Deep learning; Digital storage; Hospital data processing; Memory architecture; mHealth; Network architecture; Sensor nodes; Support vector machines; Cardio-vascular disease; Cloud computing services; Cloud storage systems; Machine learning approaches; Machine learning methods; Machine learning techniques; Mobile Health (M-Health); Technologies and applications; Learning systems | English | 2020 | 2020-10 | 10.1016/j.ins.2020.06.025 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Artificially engineered nanostrain in FeSexTe1-x superconductor thin films for supercurrent enhancement | Although nanoscale deformation, such as nanostrain in iron-chalcogenide (FeSexTe1-x, FST) thin films, has attracted attention owing to its enhancement of general superconducting properties, including critical current density (J(c)) and critical transition temperature, the development of this technique has proven to be an extremely challenging and complex process thus far. Herein, we successfully fabricated an epitaxial FST thin film with uniformly distributed nanostrain by injection of a trace amount of CeO2 inside an FST matrix using sequential pulsed laser deposition. By means of transmission electron microscopy and geometric phase analysis, we verified that the injection of a trace amount of CeO2 forms nanoscale defects, with a nanostrained region of tensile strain (epsilon(zz) approximately equal to 0.02) along the c-axis of the FST matrix. This nanostrained FST thin film achieves a remarkable J(c) of 3.5 MA/cm(2) under a self-field at 6 K and a highly enhanced J(c) under the entire magnetic field with respect to those of a pristine FST thin film. | Seo, Sehun; Noh, Heesung; Li, Ning; Jiang, Jianyi; Tarantini, Chiara; Shi, Ruochen; Jung, Soon-Gil; Jun Oh, Myeong; Liu, Mengchao; Lee, Jongmin; Gu, Genda; Jo, Youn Jung; Park, Tuson; Hellstrom, Eric E.; Gao, Peng; Lee, Sanghan | Gwangju Inst Sci & Technol, Sch Mat Sci & Engn, Gwangju 61005, South Korea; Peking Univ, Sch Phys, Electron Microscopy Lab, Beijing 100871, Peoples R China; Peking Univ, Sch Phys, Int Ctr Quantum Mat, Beijing 100871, Peoples R China; Florida State Univ, Ctr Appl Superconduct, Natl High Magnet Field Lab, Tallahassee, FL 32310 USA; Sungkyunkwan Univ, CQMS, Suwon 16419, South Korea; Sungkyunkwan Univ, Dept Phys, Suwon 16419, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Brookhaven Natl Lab, Condensed Matter Phys & Mat Sci Dept, Upton, NY 11973 USA | ; Oh, Myeongjun/IXX-1354-2023; Park, Tuson/A-1520-2012; Lee, Sanghan/AAH-1105-2019; Jiang, Jianyi/F-2549-2017; Gao, Peng/AAC-8550-2019; Tarantini, Chiara/W-4380-2019 | 57192688623; 57195513199; 56497331100; 7404829394; 10540264600; 57214096921; 15128724200; 57214096269; 57200753531; 55881826500; 7203055948; 13502586500; 8251575700; 7005369509; 58867129300; 55716521500 | sanghan@gist.ac.kr; | NPG ASIA MATERIALS | NPG ASIA MATER | 1884-4049 | 1884-4057 | 12 | 1 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY | 2020 | 10.481 | 10.9 | 1.27 | 2025-06-25 | 23 | 25 | PINNING MECHANISM; TEMPERATURE; STRAIN; SUPPRESSION | Cerium oxide; High resolution transmission electron microscopy; Iron compounds; Iron-based Superconductors; Nanotechnology; Pulsed laser deposition; Selenium compounds; Superconducting films; Tellurium compounds; Tensile strain; Complex Processes; Critical transition temperatures; Geometric phase analysis; Iron chalcogenides; Nano-scale deformation; Nanoscale defects; Superconducting properties; Superconductor thin film; Thin films | English | 2020 | 2020-01-24 | 10.1038/s41427-019-0186-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Meeting Abstract | Multicenter study of stereotactic body radiotherapy in non-small cell lung cancer (KROG 17-09) | Park, S.; Kim, J. H.; Ahn, Y. C.; Noh, J. M.; Kim, W. C.; Kang, M. K.; Cho, J. H.; Kim, J. S.; Kong, M.; Yea, J. W.; Kim, Y. S.; Choi, K. H.; Yeo, S. G. | Keimyung Univ, Dongsan Med Ctr, Radiat Oncol, Daegu, South Korea; Samsung Med Ctr, Radiat Oncol, Seoul, South Korea; Inha Univ Hosp, Radiat Oncol, Incheon, South Korea; Kyungpook Natl Univ, Radiat Oncol, Sch Med, Daegu, South Korea; Yonsei Univ, Coll Med, Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Radiat Oncol, Seongnam, South Korea; Kyung Hee Univ, Med Ctr, Radiat Oncol, Seoul, South Korea; Yeungnam Univ, Coll Med, Radiat Oncol, Daegu, South Korea; Catholic Univ, Radiat Oncol, Coll Med, Seoul, South Korea; Soonchunhyang Univ, Coll Med, Radiat Oncol, Cheonan, South Korea | Kim, Hee/F-4594-2014; Kim, Min/ACN-6827-2022; Yeo, Seung-Gu/ABC-1124-2021; Kim, Seunghyun/AAA-3402-2022 | RADIOTHERAPY AND ONCOLOGY | RADIOTHER ONCOL | 0167-8140 | 1879-0887 | 152 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 6.28 | 10.9 | 0 | English | 2020 | 2020-11 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | Postoperative radiotherapy for WHO grade II-III intracranial ependymoma in adults: An intergroup collaborative study (KROG 18-06/KNOG 18-01) | Background and purpose: To evaluate the impact of adjuvant postoperative radiotherapy (PORT) in adult WHO grade II-III intracranial ependymoma (IEPN). Materials and methods: A total of 172 pathologically confirmed adult grade II-III IEPN patients from 12 institutions were eligible. Of them, 106 (61.6%) and 66 (38.4%) patients were grade II and III, respectively. For grade II and III IEPNs, 51 (48.1%) and 59 (89.4%) patients received PORT, respectively. The median dose to the primary tumor bed was 54.0 Gy and 59.4 Gy for grade II and III patients, respectively. The prognostic impact of sex, age, performance, WHO grade, location, size, surgical extent, and PORT on local control (LC), progression-free survival (PFS), and overall survival (OS) were evaluated by univariate and multivariate analysis. Results: The median follow-up period for survivors was 88.1 months. The 5-/10-year LC, PFS, and OS rates were 64.8%/54.0%, 56.4%/44.8%, and 76.6%/71.0%, respectively. On multivariate analysis, adjuvant PORT significantly improved LC (P = 0.002), PFS (P = 0.002), and OS (P = 0.043). Older age (P < 0.001), WHO grade III (P < 0.001), larger tumor size (P = 0.004), and lesser surgical extent (P < 0.001) were also negative factors for OS. Adjuvant PORT also improved LC (P = 0.010), PFS (P = 0.007), and OS (P = 0.069) on multivariate analysis for grade II IEPNs. Conclusion: This multicenter retrospective study supports the role of adjuvant PORT in terms of disease control and survival in adult grade II-III IEPNs. Prospective randomized trials focused on individualized treatment based on molecular subtypes is warranted. (C) 2020 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 150 (2020) 4-11 | Wee, Chan Woo; Kim, Il Han; Park, Chul-Kee; Lim, Do Hoon; Nam, Do-Hyun; Yoon, Hong In; Suh, Chang-Ok; Chang, Jong Hee; Chung, Woong-Ki; Jung, Tae-Young; Park, Shin-Hyung; Kim, Chae-Yong; Kim, Young Zoon; Gwak, Ho Shin; Cho, Kwan Ho; Kim, Jin Hee; Im, Jung Ho; Kim, Woo Chul; Kim, Sung-Hwan; Kim, In Ah | SMG SNU Boramae Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Neurosurg, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurosurg, Seoul, South Korea; Yonsei Canc Ctr, Dept Radiat Oncol, Seoul, South Korea; Yonsei Canc Ctr, Dept Neurosurg, Seoul, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Radiat Oncol, Gwangju, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Neurosurg, Hwasun, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Neurosurg, Seongnam, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Changwon Hosp, Div Neurooncol, Chang Won, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Changwon Hosp, Dept Neurosurg, Chang Won, South Korea; Natl Canc Ctr, Dept Neurosurg, Goyang, South Korea; Natl Canc Ctr, Proton Therapy Ctr, Goyang, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Radiat Oncol, Daegu, South Korea; CHA Univ, Sch Med, CHA Bundang Med Ctr, Dept Radiat Oncol, Seongnam, South Korea; Inha Univ Hosp, Dept Radiat Oncol, Incheon, South Korea; St Vincents Hosp, Dept Radiat Oncol, Suwon, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Radiat Oncol, Seongnam, South Korea | ; Kim, Juhee/KFS-3069-2024; KIM, CHAE-YONG/D-5769-2012; Kim, Min/ACN-6827-2022; Cho, Hwa Jin/AFA-1420-2022; , Do Hyun Nam/C-9656-2011; Park, Chul-Kee/J-5499-2012; Kim, Yong/L-8289-2019; Kim, Sung Hwan/GQQ-1731-2022; Park, Shinhyung/LNQ-6428-2024; Kim, In/J-5426-2012 | 56702284700; 55559560100; 56424318200; 7401816010; 57190971869; 35312857100; 7102970921; 7601549862; 8707485800; 8540321700; 57203275843; 37078769600; 55574096600; 59871514800; 56507757300; 56441016600; 56096038400; 55730056400; 55816926300; 35210493700 | inah228@snu.ac.kr; | RADIOTHERAPY AND ONCOLOGY | RADIOTHER ONCOL | 0167-8140 | 1879-0887 | 150 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 6.28 | 10.9 | 0.49 | 2025-06-25 | 8 | 9 | Ependymoma; Adult; Intracranial; Radiotherapy; Survival | PROGNOSTIC-FACTORS; TUMORS; SERIES; SUPRATENTORIAL; MULTICENTER; SURVIVAL; BRAIN | Adult; Ependymoma; Intracranial; Radiotherapy; Survival | Adult; Aged; Ependymoma; Humans; Prognosis; Prospective Studies; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome; World Health Organization; adult; aged; Article; cancer prognosis; cancer radiotherapy; cancer staging; cancer survival; cerebrospinal fluid examination; conformal radiotherapy; craniospinal irradiation; ependymoma; female; follow up; human; human tissue; intensity modulated radiation therapy; intracranial tumor; Karnofsky Performance Status; major clinical study; male; multicenter study; multimodality cancer therapy; nuclear magnetic resonance imaging; outcome assessment; overall survival; postoperative care; priority journal; progression free survival; radiation dose; retrospective study; tertiary care center; tumor volume; World Health Organization; adjuvant radiotherapy; clinical trial; ependymoma; prognosis; prospective study; treatment outcome; World Health Organization | English | 2020 | 2020-09 | 10.1016/j.radonc.2020.05.045 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | Regarding: Van Diessen et al., "Safety and efficacy of reduced dose and margins to involved lymph node metastases in locally advanced non-small cell lung cancer (NSCLC) patients" | Park, Jongmoo; Yea, Ji Woon; Park, Jae Won; Park, Jaehyeon | Kyungpook Natl Univ, Chilgok Hosp, Dept Radiat Oncol, Daegu, South Korea; Yeungnam Univ, Coll Med, Dept Radiat Oncol, 170 Hyeonchung Ro, Daegu 705717, South Korea | Park, Jin-Hong/F-1829-2014; Park, Ji Won/JCD-9105-2023; Park, Jun/H-7127-2019 | 56180048900; 55305655400; 57225161977; 57208665003 | drjhyeon@ynu.ac.kr; | RADIOTHERAPY AND ONCOLOGY | RADIOTHER ONCOL | 0167-8140 | 1879-0887 | 147 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 6.28 | 10.9 | 0 | 2025-06-25 | 0 | 0 | Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Neoplasm Staging; advanced cancer; cancer radiotherapy; cancer survival; clinical effectiveness; distant metastasis; dysphagia; human; Letter; lung toxicity; lymph node metastasis; lymphocyte count; lymphocytopenia; neutrophil count; neutrophil lymphocyte ratio; overall survival; priority journal; radiation dose reduction; radiation safety; small cell lung cancer; cancer staging; lung tumor; lymph node; lymph node metastasis; non small cell lung cancer; pathology | English | 2020 | 2020-06 | 10.1016/j.radonc.2020.03.034 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | The role of the Acanthamoeba castellanii Sir2-like protein in the growth and encystation of Acanthamoeba | Background The encystation ofAcanthamoebaleads to the development of resilient cysts from vegetative trophozoites. This process is essential for the survival of parasites under unfavorable conditions. Previous studies have reported that, during the encystation ofA. castellanii, the expression levels of encystation-related factors are upregulated. However, the regulatory mechanisms for their expression during the encystation process remains unknown. Proteins in the sirtuin family, which consists of nicotinamide adenine dinucleotide-dependent deacetylases, are known to play an important role in various cellular functions. In the present study, we identified theAcanthamoebasilent-information regulator 2-like protein (AcSir2) and examined its role in the growth and encystation ofAcanthamoeba. Methods We obtained the full-length sequence for AcSir2 using reverse-transcription polymerase chain reaction. InAcanthamoebatransfectants that constitutively overexpress AcSir2 protein, SIRT deacetylase activity was measured, and the intracellular localization of AcSir2 and the effects on the growth and encystation of trophozoites were examined. In addition, the sirtuin inhibitor salermide was used to determine whether these effects were caused by AcSir2 overexpression Results AcSir2 was classified as a class-IV sirtuin. AcSir2 exhibited functional SIRT deacetylase activity, localized mainly in the nucleus, and its transcription was upregulated during encystation. In trophozoites, AcSir2 overexpression led to greater cell growth, and this growth was inhibited by treatment with salermide, a sirtuin inhibitor. When AcSir2 was overexpressed in the cysts, the encystation rate was significantly higher; this was also reversed with salermide treatment. In AcSir2-overexpressing encysting cells, the transcription of cellulose synthase was highly upregulated compared with that of control cells, and this upregulation was abolished with salermide treatment. Transmission electron microscope-based ultrastructural analysis of salermide-treated encysting cells showed that the structure of the exocyst wall and intercyst space was impaired and that the endocyst wall had not formed. Conclusions These results indicate that AcSir2 is a SIRT deacetylase that plays an essential role as a regulator of a variety of cellular processes and that the regulation of AcSir2 expression is important for the growth and encystation ofA. castellanii. | Joo, So-Young; Aung, Ja Moon; Shin, Minsang; Moon, Eun-Kyung; Kong, Hyun-Hee; Goo, Youn-Kyoung; Chung, Dong-Il; Hong, Yeonchul | Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Microbiol, Daegu, South Korea; Kyung Hee Univ, Dept Med Zool, Sch Med, Seoul, South Korea; Dong A Univ, Dept Parasitol, Coll Med, Busan, South Korea | 7101656622; 57218245601; 7401536650; 8386023500; 7201352996; 22937863200; 13310373300; 7403392847 | ychong@knu.ac.kr; | PARASITES & VECTORS | PARASITE VECTOR | 1756-3305 | 13 | 1 | SCIE | PARASITOLOGY;TROPICAL MEDICINE | 2020 | 3.876 | 10.9 | 1.03 | 2025-06-25 | 15 | 16 | Acanthamoeba castellanii; Encystation; Sirtuin-like protein; Salermide | CALORIE RESTRICTION; CAENORHABDITIS-ELEGANS; MAMMALIAN SIRTUINS; FLOW-CYTOMETRY; LIFE-SPAN; SIR2; CELLULOSE; GENE; AUTOPHAGY; INSIGHTS | Acanthamoeba castellanii; Encystation; Salermide; Sirtuin-like protein | Acanthamoeba castellanii; Amebiasis; Animals; Genes, Protozoan; Glucosyltransferases; Histone Deacetylases; Humans; Naphthols; Parasite Encystment; Phenylpropionates; Phylogeny; Protozoan Proteins; Sirtuins; Transfection; Trophozoites; sirtuin 2; synthetase; cellulose synthase; glucosyltransferase; histone deacetylase; N-(3-((2-hydroxynaphthalen-1-ylmethylene)amino)phenyl)-2-phenylpropionamide; naphthol derivative; phenylpropionic acid derivative; protozoal protein; sirtuin; Acanthamoeba castellanii; Article; cell nucleus; cellular distribution; controlled study; growth rate; microarray analysis; microbial genome; nonhuman; parasite encystment; phylogeny; protein expression; reverse transcription polymerase chain reaction; sequence analysis; transcription regulation; transmission electron microscopy; amebiasis; animal; drug effect; gene; genetic transfection; genetics; growth, development and aging; human; metabolism; physiology; procedures; trophozoite | English | 2020 | 2020-07-22 | 10.1186/s13071-020-04237-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Wireless phototherapeutic contact lenses and glasses with red light-emitting diodes | Light-mediated therapeutics have attracted considerable attention as a method for the treatment of ophthalmologic diseases, such as age-related macular degeneration, because of their non-invasiveness and the effectiveness to ameliorate the oxidative stress of retinal cells. However, the current phototherapeutic devices are opaque, bulky, and tethered forms, so they are not feasible for use in continuous treatment during the patient's daily life. Herein, we report wireless, wearable phototherapeutic devices with red light-emitting diodes for continuous treatments. Red light-emitting diodes were formed to be conformal to three-dimensional surfaces of glasses and contact lenses. Furthermore, fabricated light-emitting diodes had either transparency or a miniaturized size so that the user's view is not obstructed. Also, these devices were operated wirelessly with control of the light intensity. In addition, in-vitro and in-vivo tests using human retinal epithelial cells and a live rabbit demonstrated the effectiveness and reliable operation as phototherapeutic devices. | Park, Young-Geun; Cha, Eunkyung; An, Hyeon Seok; Lee, Kyoung-Pil; Song, Myoung Hoon; Kim, Hong Kyun; Park, Jang-Ung | Yonsei Univ, Nano Sci Technol Inst, Dept Mat Sci & Engn, Seoul 03722, South Korea; Inst Basic Sci IBS, Ctr Nanomed, Seoul 03722, South Korea; Kyungpook Natl Univ, Sch Med, Dept Ophthalmol, Daegu 41944, South Korea; Ulsan Natl Inst Sci & Technol UNIST, Sch Mat Sci & Engn, Ulsan 44919, South Korea | ; Song, Myoung/F-3766-2010; Park, Young-Geun/GLV-4849-2022; An, Hyeon Seok/GSD-2030-2022; Park, Jang-Ung/E-9224-2010 | 57197777700; 57212005786; 57204174124; 57204505517; 53064572700; 57218260940; 11739935500 | okeye@knu.ac.kr;jang-ung@yonsei.ac.kr; | NANO RESEARCH | NANO RES | 1998-0124 | 1998-0000 | 13 | 5 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 8.897 | 10.9 | 1.59 | 2025-06-25 | 42 | 40 | transparent electronics; wearable healthcare; red light-emitting diodes; phototherapies | INDUCED DAMAGE; PHOTORECEPTOR; PHOTOBIOMODULATION; TRANSPARENT; ELECTRODES; ULTRATHIN; THERAPY; SYSTEMS; SENSOR; A2E | phototherapies; red light-emitting diodes; transparent electronics; wearable healthcare | Contact lenses; Diodes; Glass; Ophthalmology; Patient treatment; Wearable technology; Age-related macular degeneration; Continuous treatments; Miniaturized sizes; phototherapies; Red light; Reliable operation; Three-dimensional surface; Transparent electronics; Light emitting diodes | English | 2020 | 2020-05 | 10.1007/s12274-019-2595-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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