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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article SLC25A33-mediated mitochondrial DNA synthesis plays a critical role in the inflammatory response of M1 macrophages by contributing to mitochondrial ROS and VDAC oligomerization M1 macrophage polarization is modulated by the release of mitochondrial DNA (mtDNA) and induces the inflammatory immune response, which is further increased by the generation of mitochondrial reactive oxygen species (mtROS). The pyrimidine nucleotide carrier SLC25A33 is located in the mitochondrial inner membrane and is linked to mtDNA synthesis, but its role in the M1 macrophage inflammatory immune response remains unclear. Here, we elucidate the regulatory mechanisms responsible for upregulation of SLC25A33 expression during M1 macrophage polarization, SLC25A33-mediated mtROS production, and the inflammatory response. SLC25A33 expression was significantly elevated in CD14+ monocytes derived from patients with sepsis and LPS/interferon-gamma (IFN-gamma)-stimulated peritoneal macrophages (PMs). SLC25A33 was upregulated by ATF4 through the MyD88-PI3K-mTORC1 pathway in LPS/IFN-gamma-stimulated PMs. Furthermore, SLC25A33 increased mtDNA synthesis and the release of mtDNA into the cytosol, which was facilitated by mtROS-mediated voltage-dependent anion channel (VDAC) oligomer formation, thereby contributing to activation of the cGAS-STING inflammatory pathway. Conversely, SLC25A33 knockdown and pyridoxal 5'-phosphate treatment, which inhibits SLC25A33 activity, decreased mtDNA release and reduced M1 macrophage polarization and associated inflammatory responses. These findings were consistent across in vitro and in vivo sepsis models, as well as in septic patients with liver abscesses. Our findings underscore the significant role of SLC25A33 in inflammation, suggesting that targeting of SLC25A33 could be a promising therapeutic strategy for the management of M1 macrophage-mediated inflammatory diseases, including sepsis. Kim, Daehoon; Jin, Jonghwa; Lee, Yu-Rim; Kim, Dong-Ho; Park, Soo-Young; Byun, Jun-Kyu; Choi, Yeon-Kyung; Park, Keun-Gyu Kyungpook Natl Univ, Dept Biomed Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, 130 Dongdeok Ro, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, 807 Hoguk Ro, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Coll Pharm, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Aging & Metab, Daegu 41566, South Korea 58171035100; 57223246243; 59712240600; 57986980100; 8620671000; 57190427423; 35335932600; 57202558343 jkbyun@knu.ac.kr; ykchoi@knu.ac.kr; kpark@knu.ac.kr; INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES INT J BIOL SCI 1449-2288 21 7 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY 2024 10 8.0 N/A 0 0 RELEASE; INSULIN; CARRIER; METABOLISM; MECHANISMS; MITOPHAGY; APOPTOSIS; SEPSIS; SLC25 Animals; DNA, Mitochondrial; Humans; Inflammation; Interferon-gamma; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitochondria; Reactive Oxygen Species; Sepsis; Voltage-Dependent Anion Channels; gamma interferon; lipopolysaccharide; mitochondrial DNA; reactive oxygen metabolite; voltage dependent anion channel; animal; biosynthesis; C57BL mouse; genetics; human; inflammation; macrophage; male; metabolism; mitochondrion; mouse; sepsis English 2025 2025 10.7150/ijbs.96563 바로가기 바로가기 바로가기 바로가기
Article A Novel Method for Kinematic Neutron-Energy Compensation in Fast-Neutron Spectroscopy Fast-neutron-energy measurements are essential for nuclear particle research and dosimetry. However, such measurements are challenging due to the low interaction probability of fast neutrons with the matter, given their small cross section for scattering and absorption compared to thermal neutrons, as well as their zero charge. Traditional neutron-energy measurement methods have limitations related to the distance and detector size. Therefore, this study proposes a novel kinematic neutron-energy compensation method that measures neutron scattering using the first detector and directly captures fast neutrons using the second detector. The scattering and post-scattering energies of neutrons are measured and used to reconstruct the neutron energy, enabling more accurate measurements of high-energy monoenergetic neutrons. This method is less sensitive to the energy and angle distribution of neutrons as they interact with the first detector and scatter toward the second detector. The energy deposited in the first detector is measured, while the scattered fast-neutron energy is determined through nuclear reactions within the second detector, enabling event-by-event compensation in energy reconstruction. Therefore, the system is not sensitive to the distance between detectors or the solid angle determined by the detector size. The performance of the system is verified using EJ-309 liquid and 7Li-enriched Cs2LiYCl6:Ce3+ scintillators. In addition, at Korea Research Institute of Standards and Science (KRISS), 14.8-MeV monoenergetic neutrons were used to characterize the proposed method, achieving an energy resolution of 2.8% full-width at half-maximum (FWHM) for measurements and energy reconstruction. Park, Hyeoungwoo; Kang, Sinchul; Yoon, Young Soo; Park, Hyeonseo; Kim, Jungho; Kim, Joong Hyun; Kim, Hong Joo; Jeong, Dongwoo; Jegal, Jin Korea Res Inst Stand & Sci, Daejeon 34113, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Seoul Natl Univ Hosp, Dept Radiat Oncol, Seoul 03080, South Korea Yoon, Young Soo/O-8580-2014; Yoon, Young Soo/LYO-5503-2024 58950744700; 57191418531; 59120296200; 57216599536; 56784564000; 57202767439; 59594633800; 57221047608; 57192238874 hyeoungwoopark@gmail.com; sinchul1216@gmail.com; ysy@kriss.re.kr; hyeonseo@kriss.re.kr; jungho@kriss.re.kr; kimjh14@kriss.re.kr; hjkim@knu.ac.kr; sinh2433@gmail.com; tb01148@gmail.com; IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT IEEE T INSTRUM MEAS 0018-9456 1557-9662 74 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2024 5.9 8.2 0 2025-05-07 0 0 Neutrons; Detectors; Energy measurement; Scattering; Energy resolution; Scintillators; Kinematics; Uncertainty; Protons; Standards; fast-neutron spectroscopy; kinematic neutron; neutron-energy reconstruction; neutron scattering; scintillator detectors TELESCOPE Energy resolution; fast-neutron spectroscopy; kinematic neutron; neutron scattering; neutron-energy reconstruction; scintillator detectors Ionization of gases; Neutron detectors; Neutrons; Photoionization; Scintillation counters; Size determination; Velocity measurement; Detector size; Energy compensation; Energy reconstruction; Energy resolutions; Fast neutron spectroscopy; Fast neutrons; Kinematic neutron; Neutron energy; Neutron energy reconstruction; Scintillator detector; Neutron scattering English 2025 2025 10.1109/tim.2025.3541752 바로가기 바로가기 바로가기 바로가기
Review A review of photocatalytic decomposition of per- and polyfluoroalkyl substances in aqueous solution Per- and polyfluoroalkyl substances (PFASs) are a key concern in aqueous environments owing to their persistence, bioaccumulation, and toxicity. Photocatalysis offers several advantages for PFAS removal compared to other treatment processes (e.g., adsorption, ion exchange, membrane filtration, plasma, ozone, and ultrasonication), including potential complete mineralization/defluorination, broad applicability (for both long-and short-chain PFASs), and cost-effective operation with the utilization of visible light. In recent years, research and review publications have been increasing on the photocatalytic degradation of PFASs. This paper provides a complete and systematic review of the most current advances in the photocatalytic removal of PFASs (2020-2025 data), and specifically assesses their photocatalytic properties (structure, band gap energy, light absorption, and surface area), environmental factors (solution pH, background ionic strength, and natural organic matter), and operating conditions (light intensity and wavelength). Overall, the findings suggest that photo-oxidation/reduction with various reactive species (h(+), e(-), (OH)-O-center dot, O-2(center dot-), and SO4 center dot-) plays a substantial role in the PFAS degradation activity. However, PFAS degradation efficiency still varies significantly depending on the catalysts, water quality conditions, and/or operating conditions. A brief discussion of future research directions is also provided to address existing knowledge gaps and resolve concerns regarding photocatalysis in real-world applications. Kim, Hak-Hyeon; Choi, Jong Soo; Jung, Bongyeon; An, Sujin; Yang, Narae; Her, Namguk; Park, Chang Min; Jang, Min; Jun, Byung-Moon; Yoon, Yeomin Ewha Womans Univ, Dept Environm Sci & Engn, 52 Ewhayeodae Gil, Seoul 03760, South Korea; ERITA Co Ltd, Environm Res Ctr, Jeongseojin Ro 410, Incheon 22689, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kwangwoon Univ, Dept Environm Engn, 447-1 Wolgye Dong, Seoul, South Korea; Kyung Hee Univ, Dept Environm Sci & Engn, 1732 Deogyeong Daero, Yongin 17104, Gyeonggi Do, South Korea Park, Chang Min/CAA-8506-2022; Jun, Byung-Moon/Y-2134-2019 56683717600; 57202287234; 57211690823; 59162816100; 58928360500; 6701721727; 57209588953; 36762550700; 55326699900; 7402126688 jbm9101@khu.ac.kr; yoony@ewha.ac.kr; JOURNAL OF ENVIRONMENTAL MANAGEMENT J ENVIRON MANAGE 0301-4797 1095-8630 389 SCIE ENVIRONMENTAL SCIENCES 2024 8.4 8.2 N/A 0 0 Photocatalysis; Perfluorooctanoic acid; Perfluorooctanesulfonic acid; Water treatment; Degradation mechanisms PERFLUOROOCTANOIC ACID PFOA; FACILE SYNTHESIS; METHYLENE-BLUE; DEGRADATION; PHOTODEGRADATION; ADSORPTION; OXIDATION; WATER; TIO2; UV Degradation mechanisms; Perfluorooctanesulfonic acid; Perfluorooctanoic acid; Photocatalysis; Water treatment Photocatalytic activity; bismuth; carbon; indium; natural organic matter; organofluorine derivative; perfluoroalkyl substance; polyfluoroalkyl substance; titanium dioxide; unclassified drug; Aqueous environment; Degradation mechanism; Ion-exchange membrane; Membrane filtrations; Operating condition; Perfluorooctanesulphonic acid; Perfluorooctanoic acid; Photocatalytic decomposition; Polyfluoroalkyl substances; Treatment process; aqueous solution; catalysis; catalyst; chemical composition; chemical compound; decomposition; degradation; photodegradation; pollutant removal; wastewater treatment; adsorption; aqueous solution; catalyst; chemical structure; decomposition; degradation kinetics; environmental factor; ionic strength; light absorption; light intensity; pH; photocatalysis; photodegradation; photooxidation; reduction (chemistry); Review; surface area; water quality; Ozone water treatment English 2025 2025-08 10.1016/j.jenvman.2025.126142 바로가기 바로가기 바로가기 바로가기
Article A strategic recovery of value-added monomer from polycarbonate waste through catalytic pyrolysis on ultra-high porous MgO The huge generation of plastic waste has become significant environmental problem. For environmentally sustainable plastic waste management, thermochemical recycling of widely used plastic waste such as polyethylene, polypropylene, polystyrene, and polyethylene terephthalate have vigorously studied. However, development of proper recycling process for other types of plastic waste is required. In this study, a thermo-catalytic treatment was applied for recovery of value-added monomers and gaseous products from polycarbonate (PC). The systematic study investigating the relationships between pyrolysis conditions (temperature, atmospheric gas, the presence of catalyst) and yield of value-added products was performed. To make the thermochemical process environmentally benign and more efficient, carbon dioxide (CO2) was used as an atmospheric gas in comparing to inert gas (N2). When CO2 was introduced, the yield of PC monomer, bisphenol A (BPA), was nearly doubled at 600 degrees C. At higher temperature, BPA yield decreased with the increased yield of gaseous products. Because CO2 was the major gaseous product, BPA recovery from the PC pyrolysis was the useful approach in PC disposal practice. To improve BPA yield from PC pyrolysis, two MgO catalysts were utilized (medium porosity MgO-1 and ultrahigh porosity MgO-2). Catalytic pyrolysis under CO2 environment increased BPA yield from 12.8 (pyrolysis without catalyst under N2) to 25.6 (MgO-1) and 30.5 wt% (MgO-2) at 600 degrees C. High porosity MgO catalyst was more effective in BPA production, and the catalyst deactivation was not shown for 4 consecutive reactions. This study informs that MgO catalyst and CO2 flow gas more than doubled the BPA yield from pyrolysis of PC in reference to conventional pyrolysis system (non-catalytic under N2). Yang, Wooyoung; Choi, Doeun; Yu, Hak Ki; Jung, Sungyup; Lee, Jechan Sungkyunkwan Univ, Dept Global Smart City, Suwon 16419, South Korea; Ajou Univ, Dept Energy Syst Res, Suwon 16499, South Korea; Ajou Univ, Dept Mat Sci & Engn, Suwon 16499, South Korea; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Sungkyunkwan Univ, Sch Civil Architectural Engn & Landscape Architect, 2066 Seobu Ro, Suwon 16419, South Korea ; Yu, Hak/B-7497-2012; Jung, Sungyup/GZG-6207-2022; Lee, Jechan/J-1229-2016 57863490200; 58772893100; 56263669500; 55073290800; 57188712886 sjung001@knu.ac.kr; jechanlee@skku.edu; JOURNAL OF ENVIRONMENTAL MANAGEMENT J ENVIRON MANAGE 0301-4797 1095-8630 373 SCIE ENVIRONMENTAL SCIENCES 2024 8.4 8.2 0 2025-05-07 1 1 Circular economy; Waste valorization; Polycarbonate; MgO catalyst; Pyrolysis INCINERATION; DEGRADATION; GASIFICATION; POLYETHYLENE; EMISSION Circular economy; MgO catalyst; Polycarbonate; Pyrolysis; Waste valorization Carbon Dioxide; Catalysis; Magnesium Oxide; Plastics; Polycarboxylate Cement; Porosity; Pyrolysis; Recycling; Waste Management; Pyrolysis; Waste management; 4,4' isopropylidenediphenol; carbon; carbon dioxide; hydrogen; inert gas; magnesium; monomer; nitrogen; oxygen; polycarbonate; volatile agent; magnesium oxide; plastic; polycarbonate; polycarboxylate cement; Bisphenol A; Bisphenols-A; Catalytic pyrolysis; Circular economy; Gaseous products; MgO; MgO catalyst; Plastics waste; Waste valorizations; ]+ catalyst; atmospheric gas; carbon dioxide; catalyst; plastic waste; porosity; pyrolysis; recycling; Article; catalysis; catalyst; chemical reaction; controlled study; covalent bond; decomposition; gas flow; melting point; plastic waste; pore size; pore volume; porosity; pyrolysis; reaction analysis; strategic reserve; surface area; temperature; thermostability; waste valorization; catalysis; chemistry; procedures; recycling; waste management; Plastic recycling English 2025 2025-01 10.1016/j.jenvman.2024.123564 바로가기 바로가기 바로가기 바로가기
Article Explainable AI-based risk assessment for pluvial floods over South Korea Analytic Hierarchy Process (AHP) of pluvial flood risk assessment has been widely used, incorporating multiple assessment indices. However, uncertainty assessment of expert judgement-based flood risk remains limited. This study proposes a Machine Learning (ML) model-based AHP approach, using pluvial flood-related data of hazard, exposure, vulnerability, and capacity of South Korea over 2002-2021. In this study, the trained eXtreme Gradient Boosting (XGBoost) and Random Forest (RF) models successfully predict flood economic losses using 21 floodrelated variables, outperforming LightGBM and CatBoost. Permutation importance scores from the trained XGBoost and RF models are used to estimate the mean and 95 % confidence intervals of the assessment factor weights. Both models show that rainfall amount, river area, population density, and green belt area are important factors for flood damage prediction, but the XGBoost (RF) model identifies impermeable areal fraction (river area) as the most important component in exposure, resulting in disparity in the uncertainty range in major cities over South Korea where the XGBoost and RF models show a high risk consistently. This study substantiates the practical application of the proposed ML based-AHP approach for uncertainty assessment of flood risk, highlighting the need for balanced land development and green infrastructure for flood mitigation. Lee, Eunmi; You, Young-Wook; Jung, Young-Hun; Kam, Jonghun Pohang Univ Sci & Technol, Div Environm Sci & Engn, Pohang 37673, South Korea; Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, Sangju 37224, South Korea; Pohang Univ Sci & Technol, Artificial Intelligence Grad Sch, Cheongam Ro 77, Pohang 37673, South Korea Kam, Jonghun/G-3550-2012; Kam, Jonghun/P-8573-2019 58616488100; 59772223300; 55195880200; 59704122600 y.jung@knu.ac.kr; jhkam@postech.ac.kr; JOURNAL OF ENVIRONMENTAL MANAGEMENT J ENVIRON MANAGE 0301-4797 1095-8630 385 SCIE ENVIRONMENTAL SCIENCES 2024 8.4 8.2 N/A 0 0 HIERARCHY PROCESS AHP; ARTIFICIAL-INTELLIGENCE; HAZARD ASSESSMENT; WEST-BENGAL; FUZZY AHP; VULNERABILITY; DISTRICT; CLIMATE; AREAS; GIS Floods; Machine Learning; Republic of Korea; Risk Assessment; South Korea; Expert systems; Risk analysis; Uncertainty analysis; rain; Analytic hierarchy; Flood risk assessments; Flood risks; Hierarchy process; Pluvials; Process approach; Random forest modeling; Risks assessments; South Korea; Uncertainty assessment; artificial intelligence; flood damage; flooding; infrastructure; rainfall; risk assessment; analytic hierarchy process; Article; controlled study; explainable artificial intelligence; flood mitigation; flooding; human; hurricane; land development; machine learning; machine learning algorithm; natural disaster; population density; precipitation; prediction; random forest; risk assessment; risk factor; river; seasonal variation; South Korea; vulnerability; machine learning; risk assessment; South Korea; Risk assessment English 2025 2025-06 10.1016/j.jenvman.2025.125640 바로가기 바로가기 바로가기 바로가기
Article Graphitic nitride decorated with silver oxide nanoparticles as p-n heterostructured catalyst for photoelectrochemical properties and visible-light photodegradation of tetracycline from wastewater Effective photodegradation of tetracycline from wastewater is critical to conserve or restore the marine environment. In this study, p-n-type heterostructured photocatalysts are prepared to show good photoexcited charge separation and quick surface catalytic reactions that are used to photodegrade tetracycline from wastewater as well as for photoelectrochemical studies. The p-n heterostructured photocatalyst was synthesized by decorating Ag2O nanoparticles onto graphitic carbon nitride (g-C3N4) sheets via hydrothermal method. The crystal structure, surface morphology, optical properties, and elemental composition were investigated to confirm the presence of Ag2O nanoparticles on the surface of g-C3N4 nanosheets. The prepared Ag2O/g-C3N4 composite photocatalyst showed tetracycline degradation up to 95.6 % in 90 min under visible light illumination, which was higher than just Ag2O (38.7 %) and g-C3N4 (17.5 %) under the same conditions. Additionally, photoelectrode showed a higher photocurrent (0.525 mA cm- 2) than g-C3N4 (0.119 mA cm- 2) and Ag2O (0.1236 mA cm- 2). Enhanced photocatalytic and photoelectrochemical activity of the composite catalyst was attributed to active interfacial charge transfer, which increased the lifespan of photogenerated charge carriers and electron density. The developed composite was used for dual purpose of leveraging the synergy between p-n-type materials for wastewater treatment and green hydrogen generation through photoelectrochemical water splitting. Wang, Rui; Vijayalakshmi, Mule; Dai, Aijia; Reddy, Kakarla Raghava; Tang, Hui; Cheolho, Bai; Shim, Jaesool; Reddy, Ch Venkata; Aminabhavi, Tejraj M. Chengdu Univ Technol, Sch Mech & Elect Engn, Chengdu 610059, Peoples R China; Yeungnam Univ, Sch Engn, Gyongsan 712749, South Korea; Kyungpook Natl Univ, Coll Humanities, 80 Daehak Ro, Daegu 41566, South Korea; Univ Sydney, Sch Chem & Biomol Engn, Sydney, NSW 2006, Australia; Univ Elect Sci & Technol China, Sch Mat & Energy, Chengdu 611731, Peoples R China; KLE Technol Univ, Ctr Energy & Environm, Sch Adv Sci, Hubballi 580031, Karnataka, India; Korea Univ, Seoul 02841, South Korea; Chandigarh Univ, Univ Ctr Res & Dev UCRO, Mohali 140413, Punjab, India 57995728600; 58511539400; 59300477800; 13611741600; 23486856000; 57190660386; 59680814400; 55665734600; 36048422400 chbai@yu.ac.kr; jshim@ynu.ac.kr; cvrphy@gmail.com; aminabhavit@gmail.com; JOURNAL OF ENVIRONMENTAL MANAGEMENT J ENVIRON MANAGE 0301-4797 1095-8630 389 SCIE ENVIRONMENTAL SCIENCES 2024 8.4 8.2 N/A 0 0 Heterostructured photocatalysts; Ag2O nanoparticles; Carbon nanomaterials; Photocatalysis; Photoelectrochemical performance; Toxic pollutants; Water treatment HIGHLY EFFICIENT; PHOTOCATALYTIC ACTIVITY; HYDROGEN GENERATION; FABRICATION; G-C3N4; AG2O; HETEROJUNCTION; DEGRADATION; TIO2; DEPOSITION Ag<sub>2</sub>O nanoparticles; Carbon nanomaterials; Heterostructured photocatalysts; Photocatalysis; Photoelectrochemical performance; Toxic pollutants; Water treatment Carbon nitride; Catalyst activity; Crystal structure; Heterojunctions; Morphology; Optical properties; Oxides; Photocatalysts; Photocatalytic activity; Photodegradation; Photoelectrochemical cells; Silver nanoparticles; Surface reactions; Synthesis (chemical); silver nanoparticle; tetracycline; Ag2O nanoparticle; Carbon nano-materials; Heterostructured photocatalyst; Photo degradation; Photoelectrochemical performance; Photoelectrochemicals; Silver oxide nanoparticles; Toxic pollutants; Visible light; ]+ catalyst; carbon; catalyst; electrochemical method; graphite; nanoparticle; photodegradation; silver; toxic material; wastewater treatment; Article; catalyst; controlled study; crystal structure; cyclic voltammetry; electric field; illumination; impedance; irradiation; light; linear sweep voltammetry; marine environment; morphology; oxygen evolution reaction; particle size; photocatalysis; photodegradation; photoelectrochemical water splitting; rate constant; surface area; surface property; waste water management; wastewater; water treatment; X ray photoemission spectroscopy; Silver oxides; Wastewater treatment English 2025 2025-08 10.1016/j.jenvman.2025.126231 바로가기 바로가기 바로가기 바로가기
Article Recovery of Swallowing Function and Prognostic Factors Associated with Exacerbation of Post-stroke Dysphagia Post-stroke dysphagia is a common and debilitating complication affecting millions of people worldwide, often leading to malnutrition, pneumonia, and reduced quality of life. This study, an interim analysis of the Korean Study Cohort for Functional and Rehabilitation, aimed to identify long-term changes and predictive factors associated with post-stroke dysphagia at 3 years after stroke. A total of 4735 patients with acute first-ever stroke, including both ischemic and hemorrhagic subgroups, were followed, and dysphagia was assessed using the ASHA-NOMS scale. All the patients were then followed up for up to 36 months. The results showed significant improvements in dysphagia up to 12 months after stroke in the total and hemorrhagic stroke group, and the decline in swallowing function after 24 months in the total stroke and ischemic stroke groups was a novel finding. The hemorrhagic stroke group showed worsening dysphagia after 30 months. It is unclear whether patients who experienced worsening of swallowing function had other conditions, including new strokes, that might have contributed to this decline. Male gender, age at stroke, K-FAST at 7 days, ASHA-NOMS scale, mRS score at 3 months, and early comprehensive rehabilitation were identified as predictors of a decrease in the ASHA-NOMS score after 24 months. Additionally, the K-MBI score at 3 months post-stroke was found to be a significant factor influencing long-term improvements in swallowing function. These findings suggest that patients should be closely monitored for dysphagia beyond 24 months after stroke onset, as swallowing function may decline over time. During follow-up, it is essential to carefully consider the multiple factors associated with this decline. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025. Lee, Seung Jun; Lee, So Young; Sohn, Min Kyun; Lee, Jongmin; Kim, Deog Young; Shin, Yong-Il; Oh, Gyung-Jae; Lee, Yang-Soo; Joo, Min Cheol; Song, Min-Keun; Han, Junhee; Ahn, Jeonghoon; Lee, Young-Hoon; Kim, Yun-Hee; Chang, Won Hyuk Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju city, South Korea; Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju city, South Korea; Department of Rehabilitation Medicine, College of Medicine, Chungnam National University, Daejeon, South Korea; Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, South Korea; Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, South Korea; Department of Rehabilitation Medicine, Pusan National University School of Medicine, Pusan National University Yangsan Hospital, Yangsan, South Korea; Department of Preventive Medicine, Wonkwang University, School of Medicine, Iksan, South Korea; Department of Rehabilitation Medicine, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu, South Korea; Department of Rehabilitation Medicine, Wonkwang University School of Medicine, Iksan, South Korea; Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, South Korea; Department of Statistics, Hallym University, Chuncheon, South Korea; Department of Health Convergence, Ewha Womans University, Seoul, South Korea; Department of Rehabilitation Medicine, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu, South Korea; Department of Physical and Rehabilitation Medicine, Sungkyunkwan University School of Medicine, Suwon, South Korea; Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, Department of Health Science and Technology, Department of Medical Device Management and Research, Department of Digital Healthcare, SAIHST, Sungkyunkwan University, Seoul, South Korea 59553828000; 57202327370; 7101840459; 57202882113; 55375583000; 55890990500; 7007056685; 57202952463; 56982599700; 55375416600; 57192890252; 8855402200; 55716155400; 57020121600; 35301717900 bluelsy900@hanmail.net; wh.chang@samsung.com; Dysphagia DYSPHAGIA 0179-051X 1432-0460 SCIE OTORHINOLARYNGOLOGY 2024 3 8.2 0 2025-05-07 0 American Speech-Language-Hearing Association National Outcomes Measurement System; Dysphagia; Prognosis; Stroke English Article in press 2025 10.1007/s00455-025-10804-8 바로가기 바로가기 바로가기
Article Performance Calculation of Pulse Shape Discrimination Based on Photoelectron Quantity Pulse shape discrimination (PSD) is a widely used technique in many experimental analyses. In this study, we specifically aimed to assess the effectiveness of PSD in accurately measuring decay time. We measured the decay times of a 0.1 wt% Gd-loaded liquid scintillator (Gd-LS) with 5 vol% Ultimagold-F added when irradiated with neutrons and gamma rays, which were emitted from a Cf-252 radiation source, using a two exponential decay model. We distinguished between gamma-like events and neutron-like events using the time-of-flight difference. Based on the measured decay times, we developed a simulation to model the waveforms. In the simulation, we adjusted the number of photoelectrons (NPE) and generated waveforms for NPE ranging from 10 to 1000 photoelectrons. We investigated the PSD performance as a function of NPE photoelectrons and determined that at least 49 photoelectrons are required for a neutron-like events rejection efficiency of 90%, while retaining 97.8% of gamma-like events. Hong, S. B.; Park, J. S. Kyungpook Natl Univ, Dept Phys, 80 Daehak Ro, Daegu 41566, South Korea 59414858100; 59633616000 jungsicpark@knu.ac.kr; PROGRESS OF THEORETICAL AND EXPERIMENTAL PHYSICS PROG THEOR EXP PHYS 2050-3911 2025 4 SCIE PHYSICS, MULTIDISCIPLINARY;PHYSICS, PARTICLES & FIELDS 2024 8.3 8.3 0 2025-05-07 0 0 English 2025 2025-04 10.1093/ptep/ptaf042 바로가기 바로가기 바로가기 바로가기
Article Pulse Shape Discrimination in JSNS² JSNS2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment that is searching for sterile neutrinos via the observation of $\bar{\nu }\ₘᵤ \rightarrow \bar{\nu }ₑ$ appearance oscillations using neutrinos from muon decay-at-rest. For this search, rejecting cosmic-ray-induced neutron events by Pulse Shape Discrimination (PSD) is essential because the JSNS2 detector is located above ground, on the third floor of the building. We have achieved 94.95%$\pm$0.15% rejection of neutron events while keeping 92.82%$\pm$1.77% of signal, electron-like events using a data-driven likelihood method. This article will report the PSD technique using the full fiducial volume of the JSNS2 detector. Dodo, T.; Cheoun, M. K.; Choi, J. H.; Choi, J. Y.; Goh, J.; Haga, K.; Harada, M.; Hasegawa, S.; Hwang, W.; Iida, T.; Jang, H., I; Jang, J. S.; Joo, K. K.; Jung, D. E.; Kang, S. K.; Kasugai, Y.; Kawasaki, T.; Kim, E. J.; Kim, J. Y.; Kim, S. B.; Kim, W.; Kinoshita, H.; Konno, T.; Lee, D. H.; Lim, I. T.; Little, C.; Marzec, E.; Maruyama, T.; Masuda, S.; Meigo, S.; Moon, D. H.; Nakano, T.; Niiyama, M.; Nishikawa, K.; Pac, M. Y.; Park, H. W.; Park, J. S.; Park, R. G.; Peeters, S. J. M.; Rott, C.; Sakai, K.; Sakamoto, S.; Shima, T.; Shin, C. D.; Spitz, J.; Suekane, F.; Sugaya, Y.; Suzuya, K.; Takeuchi, Y.; Yamaguchi, Y.; Yeh, M.; Yeo, I. S.; Yoo, C.; Yu, I Tohoku Univ, Res Ctr Neutrino Sci, 6-3 Azaaoba,Aoba Ku, Sendai 9808578, Japan; Japan Atom Energy Agcy JAEA, Adv Sci Res Ctr, 2-4 Shirakata, Tokai, Ibaraki 3191195, Japan; Soongsil Univ, Dept Phys, 369 Sangdo Ro, Seoul 06978, South Korea; Soongsil Univ, Origin Matter & Evolut Galaxies OMEG Inst, 369 Sangdo Ro, Seoul 06978, South Korea; Dongshin Univ, Lab High Energy Phys, 67 Dongshindae Gil, Naju Si 58245, Jeonranam Do, South Korea; Seoyeong Univ, Dept Fire Safety, 1 Seogang Ro, Gwangju 61268, South Korea; Kyung Hee Univ, Dept Phys, 26 Kyungheedae Ro, Seoul 02447, South Korea; Japan Atom Energy Agcy JAEA, J PARC Ctr, 2-4 Shirakata, Tokai, Ibaraki 3191195, Japan; Univ Tsukuba, Fac Pure & Appl Sci, Tennodai 1-1-1, Tsukuba, Ibaraki 3058571, Japan; Gwangju Inst Sci & Technol, Dept Phys & Photon Sci, 123 Cheomdangwagi Ro, Gwangju 61005, South Korea; Chonnam Natl Univ, Dept Phys, 77 Yongbong Ro, Gwangju 61186, South Korea; Sungkyunkwan Univ, Dept Phys, 2066 Seobu Ro, Suwon 16419, Gyeonggi Do, South Korea; Seoul Natl Univ Sci & Technol, Sch Liberal Arts, 232 Gongneung Ro, Seoul 139743, South Korea; Kitasato Univ, Dept Phys, 1 Chome-15-1 Kitazato,Minami Ward, Sagamihara, Kanagawa 2520329, Japan; Jeonbuk Natl Univ, Div Sci Educ, 567 Baekje Daero, Jeonju Si 54896, Jeollabuk Do, South Korea; Sun Yat Sen Zhongshan Univ, Sch Phys, Guangzhou 510275, Peoples R China; Kyungpook Natl Univ, Dept Phys, 80 Daehak Ro, Daegu 41566, South Korea; High Energy Accelerator Res Org KEK, Inst Particle & Nucl Studies, 1-1 Oho, Tsukuba, Ibaraki 3050801, Japan; Univ Michigan, Phys Dept, 500 S State St, Ann Arbor, MI 48109 USA; Osaka Univ, Res Ctr Nucl Phys, 10-1 Mihogaoka, Ibaraki, Osaka 5670047, Japan; Kyoto Sangyo Univ, Dept Phys, Kita Ku, Kyoto 6038555, Japan; Univ Sussex, Dept Phys & Astron, Sussex House, Brighton BN1 9RH, England; Univ Utah, Dept Phys & Astron, 201 Presidents Cir, Salt Lake City, UT 84112 USA; Brookhaven Natl Lab, Neutrino & Nucl Chem, Upton, NY 11973 USA 57218134613; 6701826023; 57221920572; 57218001597; 56448093200; 7101868035; 57205356479; 57225693783; 57351623400; 55681871200; 7202135207; 35227380700; 35227379900; 57204678963; 7409720005; 7004580646; 35227364200; 58411341500; 59088308600; 34769914200; 35227558900; 7401595856; 53063887800; 55568531297; 17137272700; 57352074100; 57115086800; 59574958200; 57221910313; 36862440800; 35278628000; 56384529800; 57219719005; 56365607000; 35227742400; 57879774700; 59633616000; 57007692600; 7003822004; 35227850400; 55940289900; 7402352432; 7202589797; 56191820400; 57205903423; 57252239200; 56978923700; 7004306568; 57225666975; 57188593997; 7202944190; 56647733700; 57207260043; 35228244700 scd0211@gmail.com; PROGRESS OF THEORETICAL AND EXPERIMENTAL PHYSICS PROG THEOR EXP PHYS 2050-3911 2025 2 SCIE PHYSICS, MULTIDISCIPLINARY;PHYSICS, PARTICLES & FIELDS 2024 8.3 8.3 0 2025-05-07 0 0 English 2025 2025-02-13 10.1093/ptep/ptaf016 바로가기 바로가기 바로가기 바로가기
Article Volumetric stability of moldable octacalcium phosphate in guided bone regeneration: a CBCT-based ex vivo study PurposeThe objective of this study was to evaluate the effect of flap suturing on the movement of graft materials during Guided Bone Regeneration (GBR) and to analyze the stability of moldable octacalcium phosphate (mOCP) depending on the type of graft material and membrane fixation method using Cone Beam Computed Tomography (CBCT).MethodsA total of 60 standardized rectangular-shaped bone defects were created in the alveolar ridges of mandibles from 5-6-month-old pigs (20 defects per group), and implants (4.0 mm in diameter, 10.0 mm in height) were placed into each defect. The control group employed particle-type OCP and a collagen membrane, experimental group 1 utilized particle-type OCP and a collagen membrane with fixation pins, and experimental group 2 employed mOCP and a collagen membrane. CBCT analysis was performed to evaluate changes in horizontal thickness (HT) at the grafted sites.ResultsCBCT analysis revealed that the percentage reduction in HT at the implant shoulder level was significantly lower in experimental group 1 (16.7%) and experimental group 2 (16.3%) compared to the control group (31.5%), with no statistically significant difference observed between experimental groups 1 and 2.ConclusionThe use of mOCP in guided bone regeneration demonstrated comparable volumetric stability to grafts utilizing collagen membranes fixed with titanium pins, suggesting its potential to simplify surgical procedures by eliminating the need for additional fixation devices. Lee, So-Ra; Kim, Jooseong; Kim, Woong; Kim, Seok-Jun; Kim, Yong-Gun; Lee, Won-Pyo Chosun Univ, Sch Dent, Dept Periodontol, Gwangju, South Korea; Yeungnam Univ, Sch Mat Sci & Engn, Gyongsan, South Korea; Chosun Univ, Inst Well Aging Medicare, Gwangju, South Korea; Chosun Univ, Chosun Univ G LAMP Project Grp, Gwangju, South Korea; Chosun Univ, Dept Integrat Biol Sci, Gwangju, South Korea; Chosun Univ, BK21 FOUR Educ Res Grp Age Associated Disorder Con, Gwangju, South Korea; Chosun Univ, Dept Biomed Sci, Gwangju, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Periodontol, Daegu, South Korea wplee8@chosun.ac.kr; INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY INT J IMPLANT DENT 2198-4034 11 1 SCIE DENTISTRY, ORAL SURGERY & MEDICINE 2024 4 8.3 0 Bone substitute; Guided bone regeneration; In vitro; Membrane; Octa calcium phosphate LATERAL RIDGE AUGMENTATION; DEHISCENCE-TYPE DEFECTS; RESORBABLE MEMBRANES; COLLAGEN MEMBRANES; BARRIER MEMBRANES; IMPLANTS; GBR; GRAFTS English 2025 2025-06-05 10.1186/s40729-025-00631-9 바로가기 바로가기 바로가기
Article Bayesian multiple changing-points detection This study investigated the application of Bayesian multiple change-point detection techniques in the context of piecewise polynomial signals. Given the limited number of existing methodologies for identifying change-points in such signals, we proposed an objective Bayesian change-point detection approach that accommodated heterogeneous error distributions. Our methodology was grounded in a piecewise polynomial regression framework and employed binary segmentation. Initially, we identified change-points across various signals using Bayesian binary segmentation. Subsequently, we applied Bayesian model selection to ascertain the most suitable polynomial order for the identified segments. This approach facilitated a change-point detection method that minimized reliance on subjective inputs. We incorporated intrinsic priors that allowed for the formulation of Bayes factors and model selection probabilities. To evaluate the efficacy of the proposed change-point detection techniques, we conducted a simulation study alongside two empirical case studies: one involving the Goddard Institute for space studies surface temperature analysis and the other concerning the daily closing stock prices of Samsung Electronics Co. Kang, Sang Gil; Lee, Woo Dong; Kim, Yongku Sangji Univ, Dept Data Sci, Wonju, South Korea; Daegu Haany Univ, Dept Selfdesign Convergence, Gyongsan, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Kyungpook Natl Univ, Inst Basic Sci, KNU G LAMP Res Ctr, Daegu, South Korea Lee, Woo-Dong/AGZ-3665-2022 56119861400; 8328822200; 47962102500 kim.1252@knu.ac.kr; AIMS MATHEMATICS AIMS MATH 2473-6988 10 3 SCIE MATHEMATICS, APPLIED;MATHEMATICS 2024 1.8 8.4 0 2025-05-07 0 0 binary segmentation; change-points detection; model selection; piecewise polynomial signals CIRCULAR BINARY SEGMENTATION; ONLINE INFERENCE; MODEL SELECTION; LINEAR-MODELS; NUMBER; CHANGEPOINTS binary segmentation; change-points detection; model selection; piecewise polynomial signals English 2025 2025 10.3934/math.2025216 바로가기 바로가기 바로가기 바로가기
Article Crucial Role of c-Myc/Monocarboxylate Transporter 4 Signaling in Capsaicin Induced Apoptotic and Anti-Warburg Effects in Hepatocellular Carcinoma Though Capsaicin from chili peppers was known to have antitumor effects in several cancers, the underlying antitumor pathogenesis of Capsaicin is not clear to date. Thus, the antitumor mechanism of Capsaicin was explored in Hep3B and Huh7 hepatocellular carcinoma (HCC) cells in relation to c-Myc/monocarboxylate transporter 4 (MCT4) signaling. To elucidate the antitumor mechanism of capsaicin, cytotoxicity assay, cell cycle analysis, Western blotting, RT-qPCR, RNA interference, ELISA, immunoprecipitation, and mouse xenograft model were used in this work. Capsaicin increased the cytotoxicity, subG1 population, and the number of TUNEL-positive bodies in Huh7 and Hep3B cells. Consistently, Capsaicin diminished the expression of pro-PARP, HK2, PKM2, LDHA, glucose transporter type 1 (Glut1), c-Myc, and monocarboxylate transporter 4 (MCT4) in Huh7 and Hep3B cells, along with decreased production of glucose, lactate, and ATP. However, a glycolysis end product pyruvate treatment reversed the capacity of Capsaicin to attenuate the expression of pro-PARP, HK2, c-Myc, and MCT4 in Hep3B cells. Furthermore, Capsaicin reduced c-Myc stability in the presence of cycloheximide and induced c-Myc ubiquitination in Hep3B cells, while c-Myc directly binds to MCT4 as a lactate transporter and downstream of c-Myc in Hep3B cells by immunoprecipitation and correlation factor (Spearman efficient = 0.0027). Furthermore, a preliminary analysis of an animal study reveals that Capsaicin significantly suppressed the growth of Hep3B cells inoculated in BALB/c nude mice without hurting body weight, liver, and spleen. Our findings provide novel evidence that Capsaicin exerts apoptotic and anti-Warburg effect via c-Myc/MCT4 signaling axis as a potent anticancer candidate for liver cancer therapy. Suh, Jin Young; Sim, Deok Yong; Ahn, Chi-Hoon; Park, Su-Yeon; Shim, Bum-Sang; Kim, Bonglee; Lee, Dae Young; Jeong, Hyo Bong; Lee, Hye Eun; Kim, Sung-Hoon Kyung Hee Univ, Coll Korean Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat Biores Grp, Daegu, South Korea; Natl Inst Hort & Herbal Sci, Dept Hort Crop Res, Rural Dev Adm, Wanju, South Korea Kim, Bonglee/AAH-9077-2020; Shim, Bum-sang/AAH-9081-2020; Lee, Hye Eun/AAE-6317-2022 57211278521; 57195947069; 57263262200; 57761564800; 56537972500; 51663469700; 57750904900; 57211762232; 51061334500; 57188861425 sungkim7@khu.ac.kr; PHYTOTHERAPY RESEARCH PHYTOTHER RES 0951-418X 1099-1573 39 1 SCIE CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY 2024 6.3 8.4 4.71 2025-05-07 1 1 Capsaicin; c-Myc; hepatocellular carcinoma; MCT4; Warburg effect LIVER-TRANSPLANT; CANCER; P53 c-Myc; Capsaicin; hepatocellular carcinoma; MCT4; Warburg effect Animals; Apoptosis; Capsaicin; Carcinoma, Hepatocellular; Cell Line, Tumor; Glycolysis; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Monocarboxylic Acid Transporters; Muscle Proteins; Proto-Oncogene Proteins c-myc; Signal Transduction; Xenograft Model Antitumor Assays; beta actin; capsaicin; caspase 3; cycloheximide; glucose transporter 1; lactate dehydrogenase; monocarboxylate transporter 4; Myc protein; capsaicin; monocarboxylate transporter; muscle protein; Myc protein; MYC protein, human; SLC16A4 protein, human; aerobic glycolysis; animal cell; animal experiment; animal model; animal tissue; apoptosis; Article; cell cycle arrest; cell cycle regulation; cell proliferation; cell viability; controlled study; cytotoxicity; enzyme linked immunosorbent assay; gene expression; glycolysis; Hep-G2 cell line; human; human cell; immunoprecipitation; liver cell carcinoma; male; mouse; MTT assay; nonhuman; oncogene c myc; overall survival; protein expression; TUNEL assay; ubiquitination; Western blotting; animal; Bagg albino mouse; drug effect; drug screening; drug therapy; liver cell carcinoma; liver tumor; metabolism; nude mouse; signal transduction; tumor cell line English 2025 2025-01 10.1002/ptr.8388 바로가기 바로가기 바로가기 바로가기
Article Optimal harvest strategies with catch-dependent pricing for chub mackerel in South Korea Chub mackerel (Scomber japonicus) is a key commercial species in South Korea. However, the catch volume of chub mackerel has experienced significant fluctuations over the past few decades, with current trends indicating a decline. Despite regulatory measures such as closed seasons, resource depletion remains a concern, thereby highlighting the requirement for effective management strategies. Numerous previous studies have proposed optimal harvest strategies by assuming constant prices. However, as large catches of mackerel tend to have lower prices, it is crucial to develop optimal harvest strategies that account for this decrease. Thus, we aim to develop a monthly optimal harvest strategy for chub mackerel that considers catch-dependent pricing. We define logarithmic, rational, and irrational catch-dependent price functions and their corresponding objective functions. In addition, we develop an optimal control system based on a discrete age-structured model. We use Pontryagin's maximum principle to prove the necessary conditions for the optimal harvest strategy under the three catch-dependent pricing functions and perform simulations using the forward-backward sweep method. We compare the optimal harvest strategies under the three catch-dependent pricing scenarios with those under a constant price. The optimal harvest strategies with the rational and irrational price functions are similar to those with a constant price, where the fishing effort increases immediately after spawning and then gradually decreases. In contrast, the optimal harvest strategy with the logarithmic price function involves a gradual increase in fishing effort from July immediately after the spawning period, with the maximum effort in June before the next spawning season. In addition, we compare the effects of monthly closed seasons across the four pricing scenarios. A closed season in July immediately after spawning provides the highest resource recovery efficiency. In contrast, a closed season in June provides the highest catch and profit efficiencies. As the cost per unit of effort increases, the fishing effort, catch, and profit decrease, while the biomass increases, and the profit decrease is smallest under the logarithmic price function. Our method can improve monthly optimal harvest strategies for other species using catch-dependent pricing functions as well as significantly contribute to enhancing fishers' profit. Jang, Geunsoo; Cho, Giphil Kyungpook Natl Univ, Nonlinear Dynam & Math Applicat Ctr, Daegu 41566, South Korea; Kangwon Natl Univ, Dept Artificial Intelligence & Software, Samcheok Si 25913, Gangwon Do, South Korea 57471384400; 56665111500 giphil@kangwon.ac.kr; ADVANCES IN CONTINUOUS AND DISCRETE MODELS ADV CONTIN DISCRET M 2731-4235 2025 1 SCIE MATHEMATICS, APPLIED;MATHEMATICS 2024 1.8 8.4 0 2025-05-07 0 0 Chub mackerel; Optimal harvest strategy; Catch-dependent pricing; Closed season STOCK ASSESSMENT; FISHERIES MANAGEMENT; POPULATION; AGE; MODEL; POLICY Catch-dependent pricing; Chub mackerel; Closed season; Optimal harvest strategy English 2025 2025-01-29 10.1186/s13662-025-03898-9 바로가기 바로가기 바로가기 바로가기
Article Efficacy of rice bran extract for alleviating depressive symptoms in adults: a randomized, double-blind, placebo-controlled trial Background: Preclinical research indicates the potential benefit of rice bran extract supplements (RBS) in improving depressive-like behaviors and symptoms. Objectives: We aimed to evaluate the efficacy and safety of an 8-wk administration of RBS in alleviating depressive symptoms among adults with mild-to-moderate symptom severity. Methods: This randomized, double-blind, placebo-controlled trial included 100 adults (aged 19–75 y) with scores of 7–24 on the Korean version of the Hamilton Depression Rating Scale (K-HDRS). Participants were randomly assigned to receive 1 g/d of RBS or a placebo for 8 wk. Evaluations at baseline and after 8 wk included mood assessments using K-HDRS, the Korean version of the Beck Depression Inventory-II, the Patient Health Questionnaire-9 (K-PHQ-9), the Beck Anxiety Inventory (K-BAI), and other psychological scales. Biomarker measurements included serum brain-derived neurotrophic factor, serotonin, dopamine, and salivary cortisol. Results: In the RBS and placebo groups, 47 and 50 participants, respectively, completed the intervention. At 8 wk, the RBS group exhibited greater reductions in K-HDRS scores compared with the placebo group (P < 0.001), with adjusted differences of −5.73 [95% confidence interval (CI): –7.07, –4.39; intention-to treat analysis (ITT)] and −5.95 [95% CI: –7.33, –4.57, per-protocol analysis (PP)], corresponding to percent changes of −45.1% (ITT) and −46.0% (PP), respectively. A trend toward greater reductions in the percent changes of K-BDI-II and K-BAI scores was observed in the RBS group compared with the placebo group (ITT and PP). Notably, K-PHQ-9 scores were lower in the RBS group than in the placebo group (P = 0.026, PP) after 8 wk of treatment. However, no significant intergroup differences were identified in other questionnaire scores or biomarker measurements. No adverse events were reported. Conclusions: RBS may provide a beneficial effect on depressive symptoms of mild-to-moderate severity in adults. Trial registration number: This study was registered in clinicaltrials.gov with registration number NCT05180136 (https://clinicaltrials.gov/study/NCT05180136). © 2025 The Author(s) Huh, Sung-Young; Lee, Ye Li; Kim, Su Hui; Lee, Sang Yeoup Department of Psychiatry, Pusan National University Yangsan Hospital and Department of Psychiatry, Pusan National University School of Medicine, Yangsan, South Korea; Integrated Research Institute for Natural Ingredients and Functional Foods, Yangsan, South Korea; Food and Bio-Industry Research Institute, School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea; Integrated Research Institute for Natural Ingredients and Functional Foods, Yangsan, South Korea, Family Medicine Clinic and Biomedical Research Institute, Pusan National University Yangsan Hospital and Department of Medical Education, Pusan National University School of Medicine, Yangsan, South Korea 57208100823; 57221761384; 59931332600; 59704453200 saylee@pnu.edu; American Journal of Clinical Nutrition AM J CLIN NUTR 0002-9165 1938-3207 122 1 SCIE NUTRITION & DIETETICS 2024 6.9 8.5 N/A 0 depression; dietary supplements; randomized controlled trial; rice bran extract; γ-oryzanol English Final 2025 10.1016/j.ajcnut.2025.05.021 바로가기 바로가기 바로가기
Article Efficient adsorption of radioactive iodine using silver-incorporated bentonite-chitosan hydrogel: Batch and column studies The discharge of radioactive iodine, particularly through nuclear wastewater, poses a persistent environmental threat, which demands effective remediation strategies. In this study, we investigated a novel chitosan-bentonitesilver (CBA) hydrogel designed to efficiently remove radioactive iodine. The bentonite-silver (Ben-Ag) composite was synthesized using a straightforward ion-exchange method and subsequently embedded in a chitosan matrix to form the hydrogel structure. The synthesized CBA hydrogels were systematically characterized using multiple analytical techniques and evaluated for iodide removal performance through batch and continuous column studies. The optimized hydrogel, CBA50, exhibited a notable maximum adsorption capacity of 21.6 mg/g, corresponding best to the Langmuir isotherm model, and kinetic analysis revealed that the data aligned closely with the PSO kinetic model, which suggests a chemisorption-driven adsorption process. Moreover, the hydrogels showed robust adsorption performance across a broad pH spectrum (pH 4-11) and in various anions and cations coexisting environments. Regeneration experiments exhibited considerable removal efficiency over five successive cycles, which highlights the potential reuse of hydrogels. Several removal mechanisms involving precipitation, electrostatic interactions, ion exchange, pore filling, and hydrogen bonding were proposed. These findings suggest that the CBA hydrogels are both efficient and environmentally friendly adsorbents for the removal of radioactive iodine in wastewater. Cha, Byungjun; Yea, Yeonji; Njaramba, Lewis Kamande; Kim, Minseok; Yoon, Yeomin; Park, Chang Min Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Ewha Womans Univ, Dept Environm Sci & Engn, 52 Ewhayeodae Gil, Seoul 03760, South Korea Park, Chang Min/CAA-8506-2022; Kamande, Lewis/JLL-5435-2023 57337280900; 57217304205; 57223183206; 59073001500; 7402126688; 57209588953 chabss7@gmail.com; dpduswl@naver.com; lewiskamande@gmail.com; alstjrdl11@naver.com; yoony@ewha.ac.kr; cmpark@knu.ac.kr; JOURNAL OF NUCLEAR MATERIALS J NUCL MATER 0022-3115 1873-4820 615 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;NUCLEAR SCIENCE & TECHNOLOGY 2024 3.2 8.5 N/A 0 0 Chitosan; Bentonite; Silver; Iodide; Hydrogels WASTE-WATER; ACTIVATED CARBON; REMOVAL; NANOPARTICLES; ADSORBENTS Bentonite; Chitosan; Hydrogels; Iodide; Silver Adsorption isotherms; Bioremediation; Batch studies; Chitosan hydrogel; Chitosan matrix; Column study; Environmental threats; Iodide; Ion-exchange methods; Radioactive iodine; Remediation strategies; Synthesised; Hydrogen bonds English 2025 2025-09 10.1016/j.jnucmat.2025.155943 바로가기 바로가기 바로가기 바로가기
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