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○ | ○ | Article | Underlying mechanisms of variation in yield asymmetry and strain hardening behavior of extruded pure Mg with Gd addition | Effects of Gd addition on the strain hardening behavior and yield asymmetry of pure Mg are investigated by subjecting extruded pure Mg, Mg-5Gd, and Mg-15Gd (all in wt%) to tension and compression tests along the extrusion direction (ED). As the amount of Gd added to pure Mg increases, the basal texture tilts toward the ED and the distribution of c -axes of grains becomes randomized. Under tension, the strain hardening rates of all the materials decrease until fracture. However, under compression, the strain hardening rate increases in the early stage of deformation in pure Mg and Mg-5Gd, whereas it continuously decreases in Mg-15Gd. Pure Mg exhibits considerably high tension-compression yield asymmetry, with a compressive yield strength (CYS) to tensile yield strength (TYS) ratio of 0.4. In contrast, Mg-5Gd exhibits excellent yield symmetry with CYS/TYS of 0.9 and Mg-15Gd exhibits reversed yield asymmetry with CYS/TYS of 1.2. Underlying mechanisms of these drastically different Gd-addition-induced deformation behaviors of the materials are discussed in terms of the crystallographic distribution of grains and the relative activation stresses of basal slip, prismatic slip, pyramidal slip, and {10-12} twinning under tension and compression. & COPY; 2022 Chongqing University. Publishing services provided by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) Peer review under responsibility of Chongqing University | Lee, Gyo Myeong; Park, Sung Hyuk | Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea | Park, Sung-Hyuk/AAE-6726-2022 | 57222810183; 54786002500 | sh.park@knu.ac.kr; | JOURNAL OF MAGNESIUM AND ALLOYS | J MAGNES ALLOY | 2213-9567 | 11 | 6 | SCIE | METALLURGY & METALLURGICAL ENGINEERING | 2023 | 15.8 | 0.6 | 2.93 | 2025-06-25 | 27 | 24 | Pure Mg; Gd addition; Texture; Yield asymmetry; Activation stress | RARE-EARTH TEXTURE; DEFORMATION-BEHAVIOR; GRAIN-SIZE; MAGNESIUM ALLOY; MG-1GD ALLOY; AS-CAST; SLIP; RECRYSTALLIZATION; EVOLUTION; DUCTILITY | Activation stress; Gd addition; Pure Mg; Texture; Yield asymmetry | Asymmetry; Compression Tests; Deformation; Exhibitions; Hardening; Slippage; Tension; Yield; Chemical activation; Compression testing; Strain hardening; Strain rate; Tensile strength; Yield stress; Activation stress; Basal textures; Gd addition; Pure Mg; Rate increase; Strain hardening behavior; Strain hardening rate; Tensile yield strength; Tension and compression; Yield asymmetry; Textures | English | 2023 | 2023-06 | 10.1016/j.jma.2022.09.008 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
○ | ○ | Article | Variations in dynamic recrystallization behavior and mechanical properties of AZ31 alloy with extrusion temperature | This study investigates the effects of extrusion temperature on the dynamic recrystallization (DRX) behavior of a Mg-3Al-1Zn-0.3Mn (AZ31, wt%) alloy during hot extrusion and on the microstructural characteristics and mechanical properties of materials extruded at 350 and 450 degrees C. An increase in the extrusion temperature causes a decrease in the amount of strain energy accumulated in the material during extrusion, because of promoted activation of pyramidal slip and dynamic recovery. This reduced strain energy weakens the DRX behavior during extrusion, which eventually results in a decrease in the area fraction of recrystallized grains of the extruded material. The material extruded at 450 degrees C has coarser grains and a stronger basal fiber texture than that extruded at 350 degrees C. As the extrusion temperature increases from 350 to 450 degrees C, the tensile yield strength (TYS) of the extruded material increases from 191.8 to 201.5 MPa, whereas its compressive yield strength (CYS) decreases from 122.5 to 111.0 MPa; consequently, its tension-compression yield stress ratio (CYS/TYS) decreases from 0.64 to 0.55. The increase in the TYS is attributed mainly to the stronger texture hardening and strain hardening effects of the extruded material, and the decrease in the CYS is attributed to the reduced twinning stress resulting from grain coarsening and texture intensification. The microstructural and textural evolutions of the materials during extrusion and the deformation and hardening mechanisms of the extruded materials are discussed in detail. | Cha, Jae Won; Park, Sung Hyuk | Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea | Park, Sung-Hyuk/AAE-6726-2022 | 57221282466; 54786002500 | sh.park@knu.ac.kr; | JOURNAL OF MAGNESIUM AND ALLOYS | J MAGNES ALLOY | 2213-9567 | 11 | 7 | SCIE | METALLURGY & METALLURGICAL ENGINEERING | 2023 | 15.8 | 0.6 | 4.46 | 2025-06-25 | 35 | 35 | Mg-Al-Zn alloy; Extrusion; Dynamic recrystallization; Microstructure; Yield asymmetry. | GRAIN-SIZE; YIELD ASYMMETRY; MAGNESIUM ALLOY; MG-ZN; MICROSTRUCTURE EVOLUTION; DEFORMATION-BEHAVIOR; COMPRESSIVE DEFORMATION; PLASTIC-DEFORMATION; TENSILE PROPERTIES; HIGH-STRENGTH | Dynamic recrystallization; Extrusion; Mg–Al–Zn alloy; Microstructure; Yield asymmetry | Coarsening; Dynamic recrystallization; Dynamics; Strain energy; Strain hardening; Strain rate; Tensile strength; Textures; Yield stress; Zinc alloys; AZ31; AZ31 alloy; Dynamic recrystallisation; Dynamic recrystallization (DRX); Extruded materials; Extrusion temperatures; Hot extrusion; Mg-Al -Zn alloys; Tensile yield strength; Yield asymmetry; Extrusion | English | 2023 | 2023-07 | 10.1016/j.jma.2022.10.003 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
○ | ○ | Article | A spatially multiplexed voltammetric magneto-sandwich assay involving Fe3O4/Fe-based metal-organic framework for dual liver cancer biomarkers | Voltammetric sandwich assays were constructed by integrating capture bioreceptors-conjugated magnetic nanocomposites, namely Fe3O4/MIL-101(Fe)-(NH)(CO)-COOH (FO/MOF) and alkaline phosphatase (ALP)labeled detection antibodies on an eight-well screen-printed carbon ink electrode (SPCIE) for the simultaneous detection of liver cancer biomarkers, human tissue transglutaminase 2 (TGM2) and heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1). Magnetic FO/MOF nanocomposites were prepared via a simple microwaveassisted method; these not only provided large surface areas for covalently attaching capture bioreceptors, but also acted as a separator for the sandwich nanocomposites magnetically isolated from solutions. TGM2 and hnRNP A1 were first adsorbed onto anti-TGM2 (JU30-02)- and hnRNP A1 aptamer-FO/MOF conjugates, respectively, in buffer or serum followed by the corresponding adsorption of ALP-anti-TGM2 (2F4) and ALP-antihnRNP A1 to form the sandwich complexes of anti-TGM2 (JU30-02)-FO/MOF/TGM2/ALP-anti-TGM2 (2F4) and hnRNP A1 aptamer-FO/MOF/hnRNP A1/ALP-anti-hnRNP A1. After being magnetically accumulated on each well of the SPCIE surface, eight different voltammetric responses due to the reaction of ALP in the sandwich nanocomplex with 4-aminophenyl phosphate to produce 4-aminophenol and subsequently oxidize to 4-quinoneimine were concurrently measured for the quantitative analyses of both biomarkers. TGM2 and hnRNP A1 dynamic ranges in a buffer were 0.05-1.5 and 0.1-5 nM, respectively, with sensitivity of 0.331 and 0.104 mu A/nM and detection and quantification limits of 6.7 and 22.3 and 19.6 and 65.3 pM, respectively. The performance was much less sensitive for undiluted serum samples, possibly due to the unavoidable matrix effect. Finally, the magneto-sandwich sensor was employed to directly analyze TGM2 and hnRNP A1 concentrations in various clinical serum samples. | Li, Jingjing; Lee, Sang Hyuk; Yoo, Dong Kyu; Woo, Ho Chul; Jhung, Sung Hwa; Jovic, Milica; Girault, Hubert; Lee, Hye Jin | Kyungpook Natl Univ, Dept Chem, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, 80 Daehakro, Daegu 41566, South Korea; Univ Appl Sci & Arts Western Switzerland HES SO Va, Sch Engn, Inst Life Technol, Diagnost Syst Res Grp, CH-1950 Sion, Switzerland; Ecole Polytech Fed Lausanne, Lab Electrochim Phys & Analyt LEPA, Rue Ind 17, CH-1951 Sion, Switzerland | ; Jhung, Sung/AAO-6683-2021; LEE, HYEJIN/W-1345-2018 | 57222707218; 55188583800; 57201339246; 57217234591; 6701659467; 55543834700; 7102360867; 56569175200 | hyejinlee@knu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 380 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2023 | 8 | 0.7 | 1.75 | 2025-06-25 | 11 | 13 | MIL-101(Fe)-(NH)(CO)-COOH; Eight-well screen-printed carbon ink electrode; Magneto-sandwich assay; Liver cancer biomarkers; Clinical serum analysis | TISSUE TRANSGLUTAMINASE; ELECTROCHEMICAL IMMUNOASSAY; CELIAC-DISEASE; PROTEIN; MICROSPHERES; EXPRESSION; ANTIBODIES; ELECTRODE; REMOVAL; CELLS | Clinical serum analysis; Eight-well screen-printed carbon ink electrode; Fe<sub>3</sub>O<sub>4</sub>/MIL-101(Fe)-(NH)(CO)-COOH; Liver cancer biomarkers; Magneto-sandwich assay | Antibodies; Biomarkers; Carbon; Chemical detection; Diseases; Electrodes; Magnetos; Metal-Organic Frameworks; Nanocomposites; Phosphatases; Voltammetry; Cancer biomarkers; Carbon ink; Clinical serum analyse; Eight-well screen-printed carbon ink electrode; Fe3O4/MIL-101(fe)-(NH)(CO)-COOH; Liver cancer biomarker; Liver cancers; Magneto-sandwich assay; Sandwich assays; Screen-printed; Serum analysis; Well screens; Magnetite | English | 2023 | 2023-04-01 | 10.1016/j.snb.2023.133313 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | Meeting Abstract | Associations of adding salt to foods with incident atrial fibrillation in theUKbiobank study | Park, Y.; Yang, P. -S.; Jang, E. S.; Yu, H. T.; Kim, T. -H.; Sung, J. -H.; Pak, H. N.; Lee, M. -H.; Joung, B. Y. | Kyungpook Natl Univ Hosp, Daegu, South Korea; Cha Bundang Med Ctr, Seongnam, South Korea; Yonsei Univ, Severance Cardiovasc Hosp, Coll Med, Seoul, South Korea | Pak, Hui-Nam/C-4266-2015 | EUROPEAN HEART JOURNAL | EUR HEART J | 0195-668X | 1522-9645 | 44 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2023 | 38.1 | 0.7 | 0 | English | 2023 | 2023-11 | 바로가기 | 바로가기 | ||||||||||||||||
○ | Meeting Abstract | Changes of hospital-level variation in use of optimal medical treatment for long-term follow-up from a multi-level methodological approach | Lee, J.; Jeong, M.; Rhee, E.; Jung, J.; Chang, E.; Kwak, H.; Jung, M.; Park, Y.; Park, B.; Kim, H.; Kim, N.; Jang, S.; Bae, M.; Yang, D.; Park, H. | Kyungpook Natl Univ Hosp, Daegu, South Korea; Chonnam Natl Univ Hosp, Cardiol, Gwangju, South Korea | EUROPEAN HEART JOURNAL | EUR HEART J | 0195-668X | 1522-9645 | 44 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2023 | 38.1 | 0.7 | 0 | English | 2023 | 2023-11 | 바로가기 | 바로가기 | |||||||||||||||||
○ | ○ | Article | Determination of tumor necrosis factor-α in serum using extended-gate field-effect transistor-based chemosensors with molecularly imprinted polymer-coated gold dendrites | Here, we developed extended-gate field-effect transistor (EG-FET)-based chemosensors with molecularly imprinted polymers (MIPs) on a gold-dendritic (AD) electrode to detect tumor necrosis factor-alpha (TNF-alpha) in serum. The poly(beta-cyclodextrin) film was electrochemically prepared on the AD electrode using a potentiodynamic technique, followed by TNF-alpha immobilization by host-guest interaction. The MIP film was formed via electropolymerization of thiophene-3-amidoxime (T3A) monomer in PBS solution with one scan cycle at an applied voltage of 0-1.2 V. After electrochemical optimization, the sensing behavior (based on drain current, I-ds) of the MIP films was investigated to explore the validity of the sensors, resulting in excellent reproducibility, reusability, and stability. Based on the Delta I-ds - CTNF-alpha regression curves obtained in serum containing various analyte concentrations, the imprinting factor (IF) of MIP-based EG-FET sensor was 5.55. The selectivity was evaluated by comparing sensing property using analogous cytokine proteins (interleukin 1 beta [IL-1 beta] and interleukin-6 [IL-6]). The MIP-based EG-FET sensors exhibited high sensitivity (LOD: 0.55 pg/mL, LOQ: 1.82 pg/mL) and excellent selectivity (coefficient (alpha)> 3). Based on the excellent sensing performances, including high sensitivity and selectivity, excellent reproducibility, robustness, reusability, and stability, our (EG-FET)-based chemosensor with TNF-alpha-recognizing MIP film can be used for the early diagnosis and point-of-care of immune-related diseases. | Yang, Jin Chul; Lim, Seok Jin; Cho, Chae Hwan; Hazarika, Deepshikha; Park, Jong Pil; Park, Jinyoung | Kyungpook Natl Univ, Dept Polymer Sci & Engn, 80 Daehak Ro, Daegu 41566, South Korea; Chung Ang Univ, Dept Food Sci & Technol, Basic Res Lab, Anseong 17546, South Korea | ; Park, Tae/G-1509-2013; PARK, JUN-YOUNG/P-5981-2015 | 56381794400; 58163180700; 57195217683; 57739151500; 9270334400; 57286293400 | jppark@cau.ac.kr;jinpark@knu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 390 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2023 | 8 | 0.7 | 1.35 | 2025-06-25 | 10 | 11 | Tumor necrosis factor-alpha; Molecular imprinting; Extended-gate field-effect transistor; Drain current; Gold dendrites; Imprinting factor | TNF-ALPHA; ELECTROCHEMICAL IMMUNOSENSOR; SENSITIVE DETECTION; BIOSENSOR | Drain current; Extended-gate field-effect transistor; Gold dendrites; Imprinting factor; Molecular imprinting; Tumor necrosis factor-alpha | Dendrimers; Diagnosis; Electrodes; Electropolymerization; Field effect transistors; Glycoproteins; Gold coatings; Macrophages; Reusability; Tumors; Chemo-sensors; Dendritics; Extended-gate field-effect transistors; Gold dendrite; Imprinting factor; Molecular imprinting; Molecularly Imprinted Polymer; Molecularly imprinted polymer films; Tumor necrosis factor-alpha; Tumor necrosis factors; Chemosensor | English | 2023 | 2023-09-01 | 10.1016/j.snb.2023.133982 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | Generation of nanogaps on porous ZnO sheets via Li-ion implantation: NO2 gas sensing with ultrafast recovery time | Nanoscale defect structures on material surfaces introduce diverse chemical physics and have received sub-stantial attention. However, nano structure distortions due to low stability and poor reproducibility have indi-cated the limitation for further electro-device applications using defect control. In this study, the higher activated electron transfer from the nanogaps (NGs) enhances the sensitivity and accelerated depletion region purifying the porous-ZnO (P-ZnO) sheets for NO2 gas-sensor applications.-2.2 nm width of NGs on the (1010) orientated P-ZnO sheets and 12% higher surface oxygen vacancies (VO) are formed by using Li-ion implantation via the lithiation process. This intrinsic electron-doped ZnO by NGs shows a reduced work function (phi) and an elevated Fermi level (EF) compared to pristine ZnO. Therefore, the reaction between NO2 gas and ZnO significantly ac-celerates owing to the activated electron transfer that carries ultrafast recovery time (-16 s), and a low limit of detection (-4 ppb) at 150 celcius are obtained for the NG-P-ZnO sheet-based gas sensor. The generation of NGs on the surface via Li-ion implantation with reliable stability provides a new strategy to improve the electrochemical reactivity of semiconducting metal oxides beyond that obtained using conventional material engineering ap-proaches, such as size, shape, and dimension control. | Kim, Min Young; Lee, Seung Yong; Kim, Juyoung; Park, Chul Oh; Shi, Wei; Min, Hyegi; Kim, Sang-il; Kim, Hyun-Sik; Shim, Young-Seok; Lee, Beom Zoo; Choi, Myung Sik; Jeong, Hyung Mo; Chun, Dong Won; Lee, Kyu Hyoung | Yonsei Univ, Dept Mat Sci & Engn, Seoul 03722, South Korea; Yonsei Univ, KIURI Inst, Seoul 03722, South Korea; Korea Inst Sci & Technol KIST, Ctr Energy Mat Res, Seoul 02792, South Korea; Univ Seoul, Dept Mat Sci & Engn, Seoul 02504, South Korea; Korea Univ Technol & Educ, Korea Sch Energy Mat & Chem Engn, Cheonan Si 31253, Chungcheongnam, South Korea; Chemland Co Ltd, Gunpo 15850, South Korea; Kyungpook Natl Univ, Sch Nano & Mat Sci & Engn, Sangju 37224, South Korea; Sungkyunkwan Univ, Sch Mech Engn, Suwon 16419, South Korea; Sungkyunkwan Univ, Dept Smart Fab Technol, Suwon 16419, South Korea; Yonsei Univ, Yonsei KIST Convergence Res Inst, Seoul 03722, South Korea | Shi, Wei/Q-6032-2019; Choi, Myung-Sik/J-5687-2012 | 57221074025; 57436380000; 57201935243; 57224363615; 56911499200; 57193909361; 36171889900; 56526077500; 36791485200; 59603579900; 57190737942; 42061388000; 15047830500; 35205856800 | hmjeong@skku.edu;chundream98@kist.re.kr;khlee2018@yonsei.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 379 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2023 | 8 | 0.7 | 1.08 | 2025-06-25 | 6 | 8 | ZnO; NO 2 gas sensing; Li-ion implantation; Nanogap; Recovery time | OXYGEN VACANCY; METAL-OXIDES | Li-ion implantation; Nanogap; NO<sub>2</sub> gas sensing; Recovery time; ZnO | Chemical detection; Electron transitions; Gas detectors; Gases; II-VI semiconductors; Ion implantation; Lithium compounds; Lithium-ion batteries; Magnetic semiconductors; Nanostructures; Nitrogen oxides; Recovery; Wide band gap semiconductors; Electron transfer; Gas sensing; Gas-sensors; Ions implantation; Li-ion implantation; Nanogaps; NO2 gas sensing; Recovery time; Ultra-fast; ZnO sheets; Zinc oxide | English | 2023 | 2023-03-15 | 10.1016/j.snb.2022.133283 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | Meeting Abstract | Impact of nutritional status and systemic immune-inflammation index on mortality in patients with acute myocardial infarction | Lee, J.; Rhee, E.; Jung, J.; Chang, E.; Jung, M.; Kwak, H.; Park, B.; Park, Y.; Kim, H.; Kim, N.; Jang, S.; Bae, M.; Yang, D.; Park, H.; Cho, Y. | Kyungpook Natl Univ Hosp, Daegu, South Korea | EUROPEAN HEART JOURNAL | EUR HEART J | 0195-668X | 1522-9645 | 44 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2023 | 38.1 | 0.7 | 0 | English | 2023 | 2023-11 | 바로가기 | 바로가기 | |||||||||||||||||
○ | Article | MRI Quantification of Cortical Bone Porosity, Mineralization, and Morphologic Structure in Postmenopausal Osteoporosis | Background: Preclinical studies have suggested that solid-state MRI markers of cortical bone porosity, morphologic structure, mineralization, and osteoid density are useful measures of bone health.Purpose: To explore whether MRI markers of cortical bone porosity, morphologic structure, mineralization, and osteoid density are affected in postmenopausal osteoporosis (OP) and to examine associations between MRI markers and bone mineral density (BMD) in postmenopausal women. Materials and Methods: In this single-center study, postmenopausal women were prospectively recruited from January 2019 to October 2020 into two groups: participants with OP who had not undergone treatment, defined as having any dual-energy x-ray absorptiometry (DXA) T-score of -2.5 or less, and age-matched control participants without OP (hereafter, non-OP). Participants underwent MRI in the midtibia, along with DXA in the hip and spine, and peripheral quantitative CT in the midtibia. Specifically, MRI measures of cortical bone porosity (pore water and total water), osteoid density (bound water [BW]), morphologic structure (cortical bone thickness), and mineralization (phosphorous [P] density [31P] and 31P-to-BW concentration ratio) were quantified at 3.0 T. MRI measures were compared between OP and non-OP groups and correlations with BMD were assessed. Results: Fifteen participants with OP (mean age, 63 years +/- 5 [SD]) and 19 participants without OP (mean age, 65 years +/- 6) were evaluated. The OP group had elevated pore water (11.6 mol/L vs 9.5 mol/L; P = .007) and total water densities (21.2 mol/L vs 19.7 mol/L; P = .03), and had lower cortical bone thickness (4.8 mm vs 5.6 mm; P < .001) and 31P density (6.4 mol/L vs 7.5 mol/L; P = .01) than the non-OP group, respectively, although there was no evidence of a difference in BW or 31P-to-BW concentration ratio. Pore and total water densities were inversely associated with DXA and peripheral quantitative CT BMD (P < .001), whereas cortical bone thickness and 31P density were positively associated with DXA and peripheral quantitative CT BMD (P = .01). BW, 31P density, and 31P-to-BW concentration ratio were positively associated with DXA (P < .05), but not with peripheral quantitative CT.Conclusion: Solid-state MRI of cortical bone was able to help detect potential impairments in parameters reflecting porosity, morphologic structure, and mineralization in postmenopausal osteoporosis.(c) RSNA, 2023 | Jones, Brandon C.; Lee, Hyunyeol; Cheng, Cheng-Chieh; al Mukaddam, Mona; Song, Hee Kwon; Snyder, Peter J.; Kamona, Nada; Rajapakse, Chamith S.; Wehrli, Felix W. | Univ Penn, Perelman Sch Med, Dept Radiol, 1 Founders Bldg, 3400 Spruce St, Philadelphia, PA 19104 USA; Appl Sci Univ Penn, Sch Engn, Dept Bioengn, 1 Founders Bldg, 3400 Spruce St, Philadelphia, PA 19104 USA; Univ Penn, Perelman Sch Med, Div Endocrinol Diabet & Metab, Dept Med, 1 Founders Bldg, 3400 Spruce St, Philadelphia, PA 19104 USA; Univ Penn, Dept Orthoped Surg, Perelman Sch Med, 1 Founders Bldg, 3400 Spruce St, Philadelphia, PA 19104 USA; Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea; Natl Sun Yat sen Univ, Dept Comp Sci & Engn, Kaohsiung, Taiwan | Jones, Brandon/AAB-6130-2019 | wehrli@pennmedicine.upenn.edu; | RADIOLOGY | RADIOLOGY | 0033-8419 | 307 | 2 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2023 | 12.1 | 0.7 | 17 | ESTIMATED STRENGTH; IN-VIVO; WATER; P-31; MICROARCHITECTURE; MECHANISMS; H-1; AGE | English | 2023 | 2023-04 | 10.1148/radiol.221810 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
○ | ○ | Article | pH-responsive circular bilayer biosensor based on the actuation of an interpenetrating polymer network comprising crosslinked nematic liquid crystals and poly(Acrylic Acid) | In this study, a sweat-based biosensor was developed for the detection of urea using a bilayer film consisting of an interpenetrating polymer network (IPN) as the top layer and a flexible poly(ethylene terephthalate) (PET) layer as the bottom layer (IPNPAA/PET). The top IPN layer had intertwined solid-state nematic liquid crystals and poly (acrylic acid) (PAA) networks. Urease was immobilised at the PAA network of the IPNPAA layer of the circularly programmed IPNPAA/PET bilayer actuator film (BAF). The urea in human sweat altered the diameter of the circular urease-immobilised IPNPAA/PET (IPNurease/PET) BAF, and was quantified by measuring the diameter using a ruler; the limit of detection was 13.2 mM and linear range was 30-60 mM. The developed circular IPNurease/PET BAF exhibited a high selectivity toward urea and excellent spike-test results with real human sweat. This novel circular IPNurease/PET BAF is promising because it is battery-free, cost-effective, and enables visual detection without sophisticated instruments. Further, the application of these IPNPAA/PET BAFs can be easily expanded to other biosensors by immobilising other receptors in the IPN. | Hussain, Saddam; Park, Soo -young | Kyungpook Natl Univ, Sch Appl Chem Engn, Polymer Nano Mat Lab, Daegu 41566, South Korea | park, soo-young/N-3170-2017; Hussain, Saddam/HMO-5050-2023 | 57213261490; 57194041850 | psy@knu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 377 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2023 | 8 | 0.7 | 1.48 | 2025-06-25 | 12 | 12 | Nematic liquid crystal; Interpenetrating polymer network; Actuator; Human sweat; Biosensor; Urea | HYDROGEL; GLUCOSE; STRIP | Actuator; Biosensor; Human sweat; Interpenetrating polymer network; Nematic liquid crystal; Urea | Actuators; Biosensors; Carboxylic acids; Ethylene; Metabolism; Nematic liquid crystals; Plastic bottles; Polyethylene terephthalates; Urea; Bi-layer; Bi-layer films; Bilayer actuators; Bottom layers; Crosslinked; Human sweat; PH-responsive; Poly(acrylic acid); Poly(ethylene terephthalate) (PET); Top layers; Cost effectiveness | English | 2023 | 2023-02-15 | 10.1016/j.snb.2022.133096 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | Substitution with Low-Osmolar Iodinated Contrast Agent to Minimize Recurrent Immediate Hypersensitivity Reaction | Background: The recurrence of hypersensitivity reaction (HSR) to low-osmolar iodinated contrast media (LOCM) remains challenging despite premedication and substitution of the LOCM.Purpose: To determine the optimal practical preventive strategy for LOCM substitution in patients with a history of prior immediate HSR to LOCM.Materials and Methods: In a retrospective study, patients with an immediate HSR to LOCM before February 2020 and who underwent subsequent exposure to LOCM until March 2021 were enrolled in five tertiary referral hospitals in South Korea. The association of recurrence of an HSR after subsequent LOCM exposures was assessed using multivariate general estimating equation analysis according to age, sex, the severity of the index HSR, premedication, and substituting LOCM based on common carbamoyl side chains, including the N-(2,3-dihydroxypropyl)-carbamoyl and N-(2,3-dihydroxypropyl)-N-methyl-carbamoyl moieties.Results: The evaluation included 3800 subsequent LOCM exposures in 1066 patients (mean age, 56.2 years +/- 13.5 [SD]; 567 [53%] female and 499 [47%] male patients). The general estimating equation analysis, using 1:1 propensity score matched data for age, sex, HSR severity, and LOCM selection, showed that premedication with corticosteroids significantly reduced recurrent HSR (odds ratio [OR], 0.72; 95% CI: 0.52, 1.00; P = .049). The change to another LOCM with a common side chain had a similar recurrence rate as using the same LOCM (OR, 0.98; 95% CI: 0.64, 1.50; P = .93), whereas the use of a different LOCM without a common side chain significantly lowered HSR recurrence (OR, 0.51; 95% CI: 0.37, 0.69; P < .001) in multivariate general estimating equation analysis. Substitution of an LOCM without a common side chain was effective regardless of the index HSR severity but was more pronounced in moderate-to-severe reactions (OR, 0.30; 95% CI: 0.16, 0.55; P < .001).Conclusion: For patients with a previous immediate HSR of any severity to LOCM, alternative LOCM without a common carbamoyl side chain reduced recurrent HSR during subsequent exposures. | Kim, Sujeong; Jeon, Kyung Nyeo; Jung, Jae-Woo; Park, Han-Ki; Lee, Whal; Lee, Jongmin; Kang, Hye-Ryun | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Allergy & Clin Immunol,Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, Daegu, South Korea; Gyeongsang Natl Univ, Sch Med, Dept Radiol, Jinju, South Korea; Gyeonsang Natl Univ, Dept Radiol, Changwon Hosp, Chang Won, South Korea; Chung Ang Univ Hosp, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med,Div Allergy & Clin Immunol, Daegu, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Radiol, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Internal Med, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Med Res Ctr, Inst Allergy & Clin Immunol, Seoul, South Korea | Park, Han-Ki/AAY-3102-2020; Lee, Jongmin/AAR-6361-2020; Kim, Sujeong/NJS-2378-2025; Jung, Jae-Woo/L-9451-2019; LEE, HYUN/ABC-6119-2021; Jeon, Kyung/ABR-3583-2022 | 36666447400; 57216630942; 57189648165; 57218664064; 7407087691; 55689919700; 7404070922 | helenmed@snu.ac.kr; | RADIOLOGY | RADIOLOGY | 0033-8419 | 309 | 1 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2023 | 12.1 | 0.7 | 1.94 | 2025-06-25 | 7 | 9 | ADVERSE-REACTIONS; CORTICOSTEROID PROPHYLAXIS; CROSS-REACTIVITY; RISK-FACTORS; MEDIA; PRETREATMENT; PREVENTION | Contrast Media; Female; Humans; Hypersensitivity; Hypersensitivity, Immediate; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; antihistaminic agent; corticosteroid; epitope; iobitridol; iodinated contrast medium; iodixanol; iohexol; iomeprol; iopamidol; iopromide; ioversol; low osmolar iodinated contrast media; n (2,3 dihydroxypropyl) n methyl carbamoy; n (2,3 dihydroxypropyl)carbamoyl; unclassified drug; contrast medium; adult; age; Article; cohort analysis; confidence interval; controlled study; disease association; disease severity; female; human; hypersensitivity; immediate type hypersensitivity; major clinical study; male; medical history; middle aged; multivariate analysis; odds ratio; premedication; prevention study; propensity score; recurrence risk; recurrent disease; retrospective study; sex; single drug dose; South Korea; tertiary care center; hypersensitivity; immediate type hypersensitivity | English | 2023 | 2023-10 | 10.1148/radiol.222467 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
○ | ○ | Article | User-friendly, signal-enhanced planar spiral coil-based magnetoelastic biosensor combined with humidity-resistant phages for simultaneous detection of Salmonella Typhimurium and Escherichia coli O157:H7 on fresh produce | A user-friendly, signal-enhanced magnetoelastic (ME) biosensor was newly constructed, consisting of three sensors, a movable pencil-type planar spiral coil, and a set of hand-held signal amplifiers. It was combined with humidity-resistant, wild-type phages instead of humidity-susceptible E2 phage to simultaneously detect Salmonella Typhimurium (ST) and Escherichia coli O157:H7 (EC) on the surface of an apple. The set of hand-held signal amplifiers, four times smaller than those in the planar spiral coil-based ME biosensor, was constructed with an optimal DC magnetic field strength of 76 G. These optimized hand-held signal amplifiers enhanced the signal amplitude of the sensor by up to 1.5 times, enabling the distinction of individual peaks from three sensors. Both phage-immobilized sensors detected each target specifically under ambient humidity without the need for a bulky humidifier. The optimized exposure time for phage binding with each target on fresh produce was 16 min, almost twice as fast as the rectangular solenoid coil-based ME biosensor. The signal-enhanced ME biosensor detected its target bacteria from a mixture of ST and EC inoculated on an apple simultaneously with an enhanced detection limit of 1.7 +/- 0.4 log CFU/25 mm2 for ST and 1.6 +/- 0.3 log CFU/25 mm2 for EC. Notably, the detection limit and sensitivity did not show significant differences between each single analyte and bacterial mixture, indicating no interference with another coexisting pathogens. Our findings highlight the signalenhanced ME biosensor as a rapid, efficient, specific, and user-friendly method for the simultaneous detection of fresh produce-borne pathogens. | Choi, In Young; Choe, Jaein; Chin, Bryan A.; Park, Mi-Kyung | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Food & Bioind Res Inst, Daegu 41566, South Korea; Auburn Univ, Dept Mech Engn, Auburn, AL 36849 USA; Kyungpook Natl Univ, Sch Food Sci & Biotechnol & Food, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Biotechnol & Food & Bioind Res Inst, 80 Daehak Ro, Daegu 41566, South Korea | Park, Mi-Kyung/J-9643-2017; choe, jaein/JMQ-8957-2023 | 57200112496; 57226770667; 24529688800; 7404491155 | ciy0219@knu.ac.kr;jane1226@knu.ac.kr;chinbry@auburn.edu;parkmik@knu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 393 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2023 | 8 | 0.7 | 0.67 | 2025-06-25 | 4 | 5 | User-friendly; Signal-enhanced; Simultaneous detection; Humidity-resistant phage; Movable planar spiral coil | SENSOR; TIME | Humidity-resistant phage; Movable planar spiral coil; Signal-enhanced; Simultaneous detection; User-friendly | Biosensors; Escherichia coli; Fruits; Salmonella; Signal detection; Fresh produce; Humidity-resistant phage; Magnetoelastics; Movable planar spiral coil; Planar spirals; Salmonella typhimurium; Signal-enhanced; Simultaneous detection; Spiral coils; User friendly; Bacteriophages | English | 2023 | 2023-10-15 | 10.1016/j.snb.2023.134179 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | ○ | Article | UV light activated g-C3N4 nanoribbons coated surface acoustic wave sensor for high performance sub-ppb level NO2 detection at room temperature | The demand for efficient gas sensors in detecting low ppb-level NO2 gas is increasing rapidly for the human life and environmental protection. In this regard, surface acoustic wave (SAW) based gas sensor with selectively coated one dimensional (1D) graphitic carbon nitride (g-C3N4/GCN) nanostructure interface layer is a viable strategy for the sub-ppb level NO2 gas detection at room temperature (RT similar to 30 degrees C). Here, we explore SAW gas sensor employed with 1D GCN nanoribbons (NRs) for NO2 detection under UV-irradiation at RT. Intriguingly, the GCN NRs SAW sensor achieves an ultrahigh frequency response (Delta f similar to 28.13 kHz), short response/recovery times (131 s/116 s), excellent selectivity to NO2 (10 ppm) gas and also records a lowest detection limit (similar to 42 ppb) under UV activation at RT. The enhanced sensing performances were attributed to the high mass loading effect induced by the enhanced charge transfer between the 1D GCN NRs surface and NO2 gas molecules, boosted by the photoexcited charge carriers, numerous surface sites, and improved specific surface area of 1D GCN NRs. The proposed GCN NRs SAW sensor demonstrates exceptional repeatability, good long-term stability with a minimal loss in its Delta f, and exhibited robust sensitivity towards NO2 (10 ppm) under diverse relative humidity conditions (0-80%) at RT. The peculiar sensing results of GCN NRs SAW sensor was elucidates using energy band theory sensing mechanism assisted with resistive type gas sensor. Overall, this study offers significant insights into the development of cost-effective real-time RT based NO2 sensor, paving the way for practical air quality monitoring. | Pasupuleti, Kedhareswara Sairam; Vidyasagar, Devthade; Ambadi, Lakshmi Narayana; Bak, Na-hyun; Kim, Song-Gang; Kim, Moon-Deock | Chungnam Natl Univ, Inst Quantum Syst IQS, 99 Daehak Ro, Daejeon 34134, South Korea; Kyungpook Natl Univ, Dept Mat Sci & Engn, 80 Daehak Ro, Daegu 41566, South Korea; Visvesvaraya Natl Inst Technol VNIT, Dept Chem, Nagpur 440010, India; Yeungnam Univ, Sch Mech Engn, Gyoungsan 38541, South Korea; Chungnam Natl Univ, Dept Phys, 99 Daehak Ro, Daejeon 34134, South Korea; Joongbu Univ, Dept Smart Informat Technol, 305 Donghen Ro, Goyang 10279, South Korea | Vidyasagar, Devthade/O-3930-2015; Pasupuleti, Kedhareswara Sairam/ABE-6605-2021 | 57219936688; 57201674442; 57580046500; 57224523743; 37112351700; 24577628800 | mdkim@cnu.ac.kr; | SENSORS AND ACTUATORS B-CHEMICAL | SENSOR ACTUAT B-CHEM | 0925-4005 | 394 | SCIE | CHEMISTRY, ANALYTICAL;ELECTROCHEMISTRY;INSTRUMENTS & INSTRUMENTATION | 2023 | 8 | 0.7 | 3.51 | 2025-06-25 | 25 | 27 | SAW sensor; NO2 gas; UV light; Mass loading | COMPOSITE; NANORODS | g-C<sub>3</sub>N<sub>4</sub> nanoribbons; Mass loading; NO<sub>2</sub> gas; SAW sensor; UV light | Air quality; Charge transfer; Chemical sensors; Cost effectiveness; Frequency response; Gas detectors; Irradiation; Nanoribbons; Nitrogen oxides; Phase interfaces; Coated surface; G-C3N4 nanoribbon; Gas-sensors; Human lives; Mass loadings; NO2 gas; Performance; Ppb levels; Surface acoustic wave sensors; UV-light; Gases | English | 2023 | 2023-11-01 | 10.1016/j.snb.2023.134471 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
○ | Meeting Abstract | Very long-term prognostic value of clinical SYNTAX score in patients undergoing percutaneous coronary intervention for left main coronary artery disease | Lee, J.; Jung, M.; Kwak, H.; Chang, E.; Jung, J.; Rhee, E.; Park, Y.; Park, B.; Kim, H.; Kim, N.; Jang, S.; Bae, M.; Yang, D.; Park, H.; Cho, Y. | Kyungpook Natl Univ Hosp, Daegu, South Korea | EUROPEAN HEART JOURNAL | EUR HEART J | 0195-668X | 1522-9645 | 44 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2023 | 38.1 | 0.7 | 0 | English | 2023 | 2023-11 | 바로가기 | 바로가기 | |||||||||||||||||
○ | ○ | Article | Interfacial ?-FAPbI3 phase stabilization by reducing oxygen vacancies in SnO2ₓ | Reducing nonradiative recombination in SnO2ₓ has been a critical point for fabricating efficient and stable perovskite solar cells (PSCs). Controlling oxygen vacancies in SnO2ₓ is an efficient strat-egy, but most research only presents the consequential results without scrutinizing the phenomenological part of the strategy. Here, we deeply examined and revealed a new beneficial effect of controlling oxygen vacancies in SnO2ₓ. Oxygen atoms of SnO2ₓ were responsible for retaining a-FAPbI3 at the FAPbI3/SnO2ₓ inter-face by controlling the formation of iodine interstitials, which are strong initiators of unfavorable perovskite phase transitions. Using crystallographic analysis, we observed suppression of these phase transitions when oxygen vacancies were mitigated in SnO2ₓ by oxidized black phosphorus quantum dots. Furthermore, formamidi-nium (FA) cation retention was also observed as a beneficial effect of the strategy by introducing hydrogen bonding sources for FA cat-ions at the interface. Our findings suggest the genuine necessity of oxygen vacancy reduction in SnO2ₓ. | Lee, Jung Hwan; Lee, SunJe; Kim, Taehee; Ahn, Hyungju; Jang, Gyu Yong; Kim, Kwang Hee; Cho, Yoon Jun; Zhang, Kan; Park, Ji-Sang; Park, Jong Hyeok | Yonsei Univ, Dept Chem & Biomol Engn, 50 Yonsei Ro, Seoul 03722, South Korea; Yonsei Univ, Spect Lab Funct Elect Syst, 50 Yonsei Ro, Seoul 03722, South Korea; Yonsei Univ, Dept Chem, 50 Yonsei Ro, Seoul 03722, South Korea; Pohang Accelerator Lab PAL, Pohang 790784, South Korea; Nanjing Univ Sci & Technol, Coll Mat & Devices, Nanjing 210094, Peoples R China; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Sungkyunkwan Univ, SKKU Adv Inst Nano Technol SAINT, Suwon 16419, South Korea; Sungkyunkwan Univ, Dept Nano Engn, Suwon 16419, South Korea | Kim, Taehee/ABD-4923-2021; KIM, Heejae/J-2173-2015; Park, Jong/A-7778-2012; Zhang, Kan/IAP-8198-2023 | 57203386233; 57211411116; 56160164800; 56452216500; 57223002393; 57220563206; 57195585942; 55249772600; 36671796300; 57194536850 | lutts@yonsei.ac.kr; | JOULE | JOULE | 2542-4351 | 7 | 2 | SCIE | CHEMISTRY, PHYSICAL;ENERGY & FUELS;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2023 | 38.6 | 0.8 | 5.52 | 2025-06-25 | 59 | 58 | FORMAMIDINIUM LEAD IODIDE; PEROVSKITE; PERFORMANCE; EFFICIENT | black phosphorus quantum dots; formamidinium cation retention; iodine interstitial; oxygen vacancies; SnO<sub>2−x</sub>; α-phase FAPbI<sub>3</sub> retention | Hydrogen bonds; Nanocrystals; Oxygen vacancies; Perovskite; Perovskite solar cells; Phosphorus; Positive ions; Semiconductor quantum dots; Beneficial effects; Black phosphorus quantum dot; Cation retention; Formamidinia cation retention; Interstitials; Iodine interstitial; Nonradiative recombination; Phase stabilization; SnO2−x; Α-phase FAPbI3 retention; cation; crystallography; efficiency measurement; interface; oxide; oxygen; perovskite; phase transition; phosphorus; reaction kinetics; reduction; solar power; tin; Iodine | English | 2023 | 2023-02-15 | 10.1016/j.joule.2022.12.006 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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