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| ○ | ○ | Article | Analyzing Usage of the Metaverse by Associations of Patients With Prostate Cancer During the 2023 Blue Ribbon Campaign: Cross-Sectional Survey Study | Background: It is important to explain early diagnosis and treatment plans to patients of prostate cancer due to the different stages that diagnosis is made at and the corresponding stage-specific treatment options, as well as the varying prognoses depending on the choices made. Although various studies have implemented metaverse-based interventions across diverse clinical settings for medical education, there is a lack of publications addressing the implementation and validation of patient education using this technology. Objective: This study explored the potential of the metaverse as an educational and informational tool for prostate cancer. We measured and analyzed participants' satisfaction and perceptions following a metaverse-based prostate cancer awareness campaign. We also evaluated the feasibility and potential effectiveness of the metaverse as a platform for hosting a virtual patient association and delivering health education. Methods: The study was conducted via a questionnaire administered from September 15 to October 20, 2023, during the Blue Ribbon Campaign organized by the Korean Urological Association and the Korean Society of Urological Oncology. The postevent questionnaire was designed to assess the effectiveness of using the metaverse to increase awareness of prostate cancer. A total of 119 participants, including patients, caregivers, and members of the general population, completed the survey within the metaverse space and assessed their satisfaction and perceived awareness using a 5-point Likert scale. Results: The mean educational satisfaction score was 4.17 (SD 0.65), the mean psychological satisfaction score was 4.06 (SD 0.70), the mean overall satisfaction score was 4.12 (SD 0.72), and the mean awareness score was 4.09 (SD 0.72) out of a possible 5 points. Among responses rated 4 or higher ("agree" or "strongly agree"), 82.8% (394/476) were in the educational aspect, 76.6% (365/476) in psychological satisfaction, 81% (289/357) in overall satisfaction, and 80.4% (287/357) in awareness. Statistical analysis revealed significant differences in psychological (median 4.0, IQR 3.50-4.63, vs median 4.50, IQR 4.0-4.56) and overall (median 4.0, IQR 3.67-4.83, vs median 4.33, IQR 4.0-4.67) aspects between the general population group and patients and caregivers (median 4.0, IQR 3.33-4.33, vs median 4.67, IQR 4.0-4.67). Conclusions: The findings suggest that the metaverse holds promise as a platform for health care education and patient support, offering accessible and engaging experiences for patients, caregivers, and members of the general population. Our approach demonstrated a positive influence on participants' satisfaction and perceived awareness, highlighting its potential to enhance health communication and patient engagement. Despite these encouraging results, limitations, such as the sample being skewed toward younger participants and reliance on self-reported data, underscore the need for more rigorous and multidimensional assessment strategies. Future studiesshouldincorporate objectiveknowledge assessments, behavioral follow-ups, and qualitative methods to better evaluate the intervention's effectiveness. This study provides early evidence that metaverse-based interventions can support disease awareness and promote preventive health behaviors, contributing to the ongoing evolution of digital health education. | Jo, Jung Ki; Kim, Yeeun; Ha, Yun-Sok; Kim, Kwang Taek; Yoo, Sangjun; Choi, Woo Suk; Yang, Jihye; Shin, Jaeeun; Kim, Sun Il; Kim, Jeong Hyun | Hanyang Univ, Coll Med, Dept Urol, Seoul, South Korea; Hanyang Univ, Dept Med & Digital Engn, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Gachon Univ, Gil Med Ctr, Dept Urol, Incheon, South Korea; Seoul Natl Univ, Boramae Med Ctr, Seoul Metropolitan Govt, Dept Urol, Seoul, South Korea; Konkuk Univ, Med Ctr, Sch Med, Dept Urol, Seoul, South Korea; Enzaim Hlth, Seoul, South Korea; Ajou Univ, Sch Med, Dept Urol, Suwon, South Korea; Kangwon Natl Univ, Sch Med, Dept Urol, Bldg 2,1 Kangwondaehakm Gil, Chunchon 24341, South Korea | 37060991000; 59893602600; 35487226400; 59893968700; 38461673200; 59698695800; 59893227000; 59893968800; 59893227100; 59893968900 | urodr348@kangwon.ac.kr; | JOURNAL OF MEDICAL INTERNET RESEARCH | J MED INTERNET RES | 1438-8871 | 27 | SCIE | HEALTH CARE SCIENCES & SERVICES;MEDICAL INFORMATICS | 2024 | 6 | 6.2 | 0 | 2025-06-11 | 0 | 0 | virtual reality; urology; prostatic neoplasm; self-help group; patient satisfaction; survey; questionnaire; digital health; prostate cancer; cancer; cross-sectional study; metaverse; medical education; patient education; patient engagement; technology; oncology; effectiveness; awareness; healthcare; urologic malignancy; morbidity; Korean | FOLLOW-UP; HEALTH; INTERVENTION; SATISFACTION; BEHAVIORS; KNOWLEDGE; BELIEFS; PEOPLE | awareness; cancer; cross-sectional study; digital health; effectiveness; healthcare; Korean; medical education; metaverse; morbidity; oncology; patient education; patient engagement; patient satisfaction; prostate cancer; prostatic neoplasm; questionnaire; self-help group; survey; technology; urologic malignancy; urology; virtual reality | Adult; Aged; Cross-Sectional Studies; Humans; Male; Middle Aged; Patient Education as Topic; Patient Satisfaction; Prostatic Neoplasms; Republic of Korea; Surveys and Questionnaires; adult; Article; awareness; cancer surgery; care behavior; convergent validity; cross-sectional study; demographics; digital technology; disappointment; discriminant validity; female; geographic distribution; health education; human; internal consistency; major clinical study; male; metaverse; middle aged; perception; prostate cancer; psychological aspect; questionnaire; satisfaction; aged; diagnosis; patient education; patient satisfaction; procedures; prostate tumor; psychology; South Korea; therapy | English | 2025 | 2025-05-13 | 10.2196/63030 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Enhanced lithium-ion battery separators via facile fabrication of sulfonated cellulose nanofiber | This study aims to develop a facile method for fabricating lithium-ion battery (LIB) separators derived from sulfonate-substituted cellulose nanofibers (CNFs). Incorporating taurine functional groups, aided by an acidic hydrolysis process, significantly facilitated mechanical treatment, yielding nanofibers suitable for mesoporous membrane fabrication via vacuum filtration. The fabricated separators exhibited an electrolyte uptake of approximately 200%, more than double that of commercial polyethylene separators, demonstrated excellent thermal stability even at temperatures exceeding 240 degrees C, and showed superior structural properties in FTC separators compared to TC separators. Sulfonate groups play a crucial role in inducing electrostatic repulsion between fibers, thereby enhancing ionic conductivity. This advancement resulted in a high electrochemical performance comparable to that of commercial separators, thus demonstrating its suitability for fast-charging applications in LIBs. This study highlights the pivotal role of sulfonate CNFs in producing high-performance LIB separators using a variety of eco-friendly functionalized biopolymers toward the development of high-performance sustainable energy storage materials. | Lee, Junhyeok; Kim, Hyeyun; Jeong, Soyeon; Yang, Junghoon; Suhr, Jonghwan; Jo, Jaemin; Koo, Bonwook | Sungkyunkwan Univ, Dept Polymer Sci & Engn, Seoul, South Korea; Korea Inst Sci & Technol, Extreme Mat Res Ctr, Seoul 02792, South Korea; State Univ New York, Dept Chem Engn, Coll Environm Sci & Forestry, Syracuse, NY 13210 USA; Korea Inst Ind Technol KITECH, Carbon & Light Mat Applicat Res Grp, Jeonju 54853, South Korea; Sungkyunkwan Univ, Sch Mech Engn, Suwon 2066, Gyeonggi, South Korea; Kyungpook Natl Univ, Sch Forestry Sci & Landscape Architecture, Daegu 41566, South Korea | ; Jeong, Soyeon/IYJ-1257-2023 | 57997760300; 56981372900; 55960344300; 57218299505; 7006624684; 57218619190; 57219957247 | hyeyunkim@kist.re.kr; bkoo@knu.ac.kr; | CELLULOSE | CELLULOSE | 0969-0239 | 1572-882X | 32 | 1 | SCIE | MATERIALS SCIENCE, PAPER & WOOD;MATERIALS SCIENCE, TEXTILES;POLYMER SCIENCE | 2024 | 4.8 | 6.2 | 0 | 2025-05-07 | 2 | 1 | Cellulose nanofibers; Taurine cellulose; Ion-conductive cellulose; Lithium-ion battery separators; Sustainable battery technology | GEL POLYMER ELECTROLYTE; CARBOXYMETHYL CELLULOSE; LI; OXIDATION; GRAPHITE; BEHAVIOR; FILMS | Cellulose nanofibers; Ion-conductive cellulose; Lithium-ion battery separators; Sustainable battery technology; Taurine cellulose | Cellulose; Construction; Electrolytes; Lithium; Performance; Processes; Separators; Thermal Stability; Electrolytes; Fast charging (Batteries); Lithium-ion batteries; Nanocellulose; Battery separators; Battery technology; Cellulose nanofibers; Ion batteries; Ion-conductive cellulose; Lithium ions; Lithium-ion battery separator; Sulphonates; Sustainable battery technology; Taurine cellulose; Nanofibers | English | 2025 | 2025-01 | 10.1007/s10570-024-06274-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | New Results on Interval Type-3 Fuzzy Control for Nonlinear Time-Delay Systems Using Convex Relaxation Technique | In this article, the interval type-3 fuzzy-based state feedback control is proposed for the stabilization problem of interval type-3 fuzzy systems (IT3FSs) subject to time-varying delay. Specifically, to improve the model accuracy and control capabilities, we proposed a nonparallel distributed compensation-based controller approach, be precise, the system and controller adopts the distinct membership functions. Moreover, the stability analysis of IT3FSs in the state space form is studied newly in this article. Besides the primary membership function that exists for interval type-2 fuzzy systems (IT2FSs), the IT3FSs possess the secondary membership function to handle the overall uncertainty which enacts the superiority of the proposed work. Notably, the adequate stability criteria are derived in the form of linear matrix inequality (LMI) using the Lyapunov stability theorem. Additionally, the convex relaxation technique is used to strengthen the design flexibility and achieve the faster convergence rate, which converts an optimization problem with a vector variable to a convex program with a matrix variable, via a lifting technique. A noteworthy aspect is that the application of the convex relaxation technique in the context of IT3FSs is proposed for the first time in literature. Finally, the comparative results between IT2FSs and IT3FSs are shown via two illustrative examples, including the inverted-pendulum model, to underscore the efficacy and practical implementations of the developed control methodology. | Harikaran, B.; Harshavarthini, S.; Lee, Sangmoon; Sakthivel, R.; Sathiyaraj, T. | Vellore Inst Technol Chennai, Sch Adv Sci, Dept Math, Chennai 600127, India; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Bharathiar Univ, Dept Appl Math, Coimbatore 641046, India; UCSI Univ, Inst Actuarial Sci & Data Analyt, Kuala Lumpur 56000, Malaysia | Sathiyaraj, T/N-3522-2016; Lee, Sangmoon/C-4502-2018; Rathinasamy, Sakthivel/R-1832-2018 | 59465258400; 57204646660; 59510733500; 6701666350; 57015474500 | harikaran.b2022@vitstudent.ac.in; varthiniksp@gmail.com; moony@knu.ac.kr; krsakthivel@buc.edu.in; sathiyaraj@ucsiuniversity.edu.my; | IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS | IEEE T SYST MAN CY-S | 2168-2216 | 2168-2232 | 55 | 5 | SCIE | AUTOMATION & CONTROL SYSTEMS;COMPUTER SCIENCE, CYBERNETICS | 2024 | 8.7 | 6.2 | 0 | 2025-05-07 | 0 | 1 | Delays; Vectors; Time-varying systems; Stability criteria; Optimization; Electronic mail; Delay effects; Thermal stability; Mathematical models; Linear matrix inequalities; Convex relaxation technique; interval type-3 fuzzy systems (IT3FSs); stabilization; time-varying delay | UNCERTAINTIES; STABILITY | Convex relaxation technique; interval type-3 fuzzy systems (IT3FSs); stabilization; time-varying delay | Adaptive control systems; Convex optimization; Delay control systems; Feedback control; Fuzzy control; Linear matrix inequalities; Lyapunov functions; Pendulums; Stability criteria; Stabilization; State feedback; State space methods; Time varying control systems; Convex relaxation; Convex relaxation technique; Interval type-2 fuzzy; Interval type-3 fuzzy system; Memberships function; New results; Nonlinear time delay systems; Relaxation techniques; Time-varying delay; Type-2 fuzzy systems; Membership functions | English | 2025 | 2025-05 | 10.1109/tsmc.2025.3543170 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Phosphorylation of an RNA-Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging | The metazoan lifespan is determined in part by a complex signaling network that regulates energy metabolism and stress responses. Key signaling hubs in this network include insulin/IGF-1, AMPK, mTOR, and sirtuins. The Hippo/Mammalian Ste20-like Kinase1 (MST1) pathway has been reported to maintain lifespan in Caenorhabditis elegans, but its role has not been studied in higher metazoans. In this study, we report that overexpression of Hpo, the MST1 homolog in Drosophila melanogaster, decreased lifespan with concomitant changes in lipid metabolism and aging-associated gene expression, while RNAi Hpo depletion increased lifespan. These effects were mediated primarily by Hpo-induced transcriptional activation of the RNA-binding protein maternal expression at 31B (Me31b)/RCK, resulting in stabilization of mRNA-encoding a lipolytic hormone, Akh. In mouse adipocytes, Hpo/Mst1 mediated adipocyte differentiation, phosphorylation of RNA-binding proteins such as Rck, decapping MRNA 2 (Dcp2), enhancer Of MRNA decapping 3 (Edc3), nucleolin (NCL), and glucagon mRNA stability by interacting with Rck. Decreased lifespan in Hpo-overexpressing Drosophila lines required expression of Me31b, but not DCP2, which was potentially mediated by recovering expression of lipid metabolic genes and formation of lipid droplets. Taken together, our findings suggest that Hpo/Mst1 plays a conserved role in longevity by regulating adipogenesis and fatty acid metabolism. © 2025 The Author(s). Aging Cell published by Anatomical Society and John Wiley & Sons Ltd. | Yeom, Eunbyul; Mun, Hyejin; Lim, Jinhwan; Chun, Yoo Lim; Min, Kyung-Won; Lambert, Johana; Cowart, L. Ashley; Pierce, Jason S.; Ogretmen, Besim; Cho, Jung-Hyun; Chang, Jeong Ho; Buchan, J. Ross; Pitt, Jason; Kaeberlein, Matt; Kang, Sung-Ung; Kwon, Eun-Soo; Ko, Seungbeom; Choi, Kyoung-Min; Lee, Yong Sun; Ha, Yoon-Su; Kim, Seung-Jin; Lee, Kwang-Pyo; Kim, Hyo-Sung; Yang, Seo Young; Shin, Chang Hoon; Yoon, Je-Hyun; Lee, Kyu-Sun | School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, South Korea, KNU G-LAMP Project Group, KNU Institute of Basic Sciences, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu, South Korea, Neurophysiology and Metabolism Research Group, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States, Department of Oncology Science, University of Oklahoma, Oklahoma City, OK, United States; Department of Environmental and Occupational Heatlh, University of California, Irvine, CA, United States, Translational Gerontology Branch, National Institute of Aging Intramural Research Program, Baltimore, MD, United States; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States, Department of Biology, College of Natural Sciences, Gangneung-Wonju National University, Gangneung, South Korea; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States, Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, United States, Hunter Holmes McGuire Veteran's Affairs Medical Center, Richmond, VA, United States; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, United States, Hunter Holmes McGuire Veteran's Affairs Medical Center, Richmond, VA, United States; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States; Department of Biology Education, Kyungpook National University, Daegu, South Korea; Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ, United States; Department of Laboratory Medicine and Pathology, University of Washington, Washington, DC, United States; Department of Laboratory Medicine and Pathology, University of Washington, Washington, DC, United States; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Baltimore, MD, United States, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Aging Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States; Department of Oncology Science, University of Oklahoma, Oklahoma City, OK, United States; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, South Korea; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, South Korea; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, South Korea; Aging Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, South Korea, KNU G-LAMP Project Group, KNU Institute of Basic Sciences, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu, South Korea; Department of Biology Education, Kyungpook National University, Daegu, South Korea; Department of Oncology Science, University of Oklahoma, Oklahoma City, OK, United States; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, United States, Department of Oncology Science, University of Oklahoma, Oklahoma City, OK, United States, Department of Pathology, University of Oklahoma, Oklahoma City, OK, United States; Neurophysiology and Metabolism Research Group, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea, School of Pharmacy, Sungkyunkwan University, Suwon, South Korea | 59510719100; 57216672802; 48061183600; 57212409596; 54417697400; 57204010515; 7801513217; 23478087400; 7003716875; 56650401200; 57203598905; 59697708800; 7103389549; 6602710772; 24464315500; 56769008800; 57212308322; 59405296800; 47861261200; 57487862900; 57194395682; 56315570600; 57226241873; 57215036954; 59478304900; 55318967100; 24577234300 | ekuse74@kribb.re.kr; jehyun-yoon@ouhsc.edu; | Aging Cell | AGING CELL | 1474-9718 | 1474-9726 | 24 | 6 | SCIE | CELL BIOLOGY;GERIATRICS & GERONTOLOGY | 2024 | 7.1 | 6.2 | 0 | 2025-05-07 | 0 | adipocyte; differentiation; fat body; hippo; lifespan; lipid metabolism; mRNA decay | Adipose Tissue; Aging; Animals; Drosophila melanogaster; Drosophila Proteins; Intracellular Signaling Peptides and Proteins; Lipid Metabolism; Longevity; Mice; Phosphorylation; Protein Serine-Threonine Kinases; RNA-Binding Proteins; fat droplet; glucagon; lipotropin; maternal expression at 31B protein; messenger RNA; nucleolin; RNA binding protein; threonine; unclassified drug; Drosophila protein; hpo protein, Drosophila; protein serine threonine kinase; RNA binding protein; signal peptide; adipocyte; adipogenesis; adipose tissue; adult; aging; amino terminal sequence; animal cell; animal tissue; Article; Caenorhabditis elegans; cell differentiation; controlled study; Drosophila melanogaster; fatty acid metabolism; female; gene overexpression; hippo signaling; immunoprecipitation; lifespan; lipolysis; longevity; male; mouse; nonhuman; protein depletion; protein phosphorylation; RNA interference; RNA pull-down; RNA stability; transcription initiation; animal; genetics; lipid metabolism; metabolism; phosphorylation | English | Final | 2025 | 10.1111/acel.70022 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Structural Analysis of Cerebral Organoids Using Confocal Microscopy and Transmission/Scanning Electron Microscopy | Cerebral organoid cultures from human-induced pluripotent stem cells are widely used to study complex human brain development; however, there is still limited ultrastructural information regarding the development. In this study, we examined the structural details of cerebral organoids using various microscopy techniques. Two protocols were chosen as representative methods for the development of brain organoids: the classic whole-cerebral organoid (Whole-CO) culture technique, and the air-liquid interface-cerebral organoid (ALI-CO) culture technique. Immunostained confocal laser scanning microscopy (CLSM) revealed the formation of the CTIP2- and TBR1-positive cortical deep layer on days 90 and 150, depending on the developmental progress of both methods. Furthermore, the presence of astrocytes and oligodendrocytes was verified through immunostained CLSM utilizing two-dimensional and three-dimensional reconstruction images after a 150-day period. Transmission electron microscopy analysis revealed nanometer-resolution details of the cellular organelles and neuron-specific structures including synapses and myelin. Large-area scanning electron microscopy confirmed the well-developed neuronal connectivity from each culture method on day 150. Using those microscopy techniques, we clearly showed significant details within two representative culture protocols, the Whole-CO and ALI-CO culture methods. These multi-level images provide ultrastructural insight into the features of cerebral organoids depending on the developmental stage. | Noh, Seulgi; Park, Yurim; Kim, Beomsue; Mun, Ji Young | Korea Brain Res Inst KBRI, Neural Circuits Res Grp, Daegu, South Korea; Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept Brain Sci, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, Daegu, South Korea | 57216131076; 57826046700; 57208813066; 8654053900 | kimbs@kbri.re.kr; mjy1026@gmail.com; | MICROSCOPY AND MICROANALYSIS | MICROSC MICROANAL | 1431-9276 | 1435-8115 | 31 | 1 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;MICROSCOPY | 2024 | 3 | 6.2 | 0 | 2025-05-07 | 0 | 0 | air-liquid interface; cerebral organoid; large-area scanning electron microscopy; transmission electron microscopy; ultrastructure | PLURIPOTENT STEM-CELLS; PSYCHIATRIC-DISORDERS; BRAIN ORGANOIDS; MITOCHONDRIAL DYNAMICS; DIVERSITY; MODELS; NEUROGENESIS; METABOLISM; REVEAL; MOUSE | air–liquid interface; cerebral organoid; large-area scanning electron microscopy; transmission electron microscopy; ultrastructure | Brain; Humans; Induced Pluripotent Stem Cells; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Neurons; Organoids; brain; confocal microscopy; cytology; human; induced pluripotent stem cell; nerve cell; organoid; procedures; scanning electron microscopy; transmission electron microscopy; ultrastructure | English | 2025 | 2025-02-25 | 10.1093/mam/ozae119 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Ultrastructural Study of Ciliary Fragmentation in Renal Tubules During Ischemia-Reperfusion Injury | Primary cilia on renal tubular cells are critical for kidney function. This study investigated how acute kidney injury affects cilia length, specifically focusing on their shortening during ischemia-reperfusion injury. Using Sprague-Dawley rats, renal pedicles were clamped for 30 min followed by six hours of reperfusion. Kidney tissues were analyzed using confocal laser scanning microscopy and scanning electron microscopy. Acetylated alpha-tubulin and specific markers such as aquaporin 1 and H + -ATPase were used to identify proximal tubules and collecting ducts. Under normal conditions, renal tubular cells exhibited long primary cilia. Following injury, significant shortening of primary cilia was observed in both proximal tubules and collecting ducts. Intermingled microvilli in proximal tubules complicated ultrastructural observation. However, the collecting duct exhibited distinct responses. While intercalated cells detached into the lumen, principal cells remained attached to the basal lamina. Electron microscopy confirmed the shortening of cilia in principal cells, often accompanied by bulging regions of varying sizes, observed at either the tip or middle, and appearing as single or multiple structures. These findings demonstrate that acute ischaemic injury induces ciliary fragmentation in collecting duct principal cells. The observed bulging in cilia undergoing shortening may indicate potential mechanisms underlying ciliary fragmentation. | Chultemsuren, Mungunchimeg; Lee, Su-Youn; Jee, Mi Jin; Park, Kwon Moo; Han, Ki-Hwan | Ewha Womans Univ, Coll Med, Dept Anat, Room 503,5th Floor,25,Magokdong-Ro 2-Gil,Gangseo G, Seoul 07804, South Korea; Ewha Womans Univ, Nanoimaging Lab, Coll Med, Room B234,Basement 2nd Floor,25,Magokdong Ro 2-Gil, Seoul 07804, South Korea; Kyungpook Natl Univ, Dept Anat BK21 Plus, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Sch Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea | khhan@ewha.ac.kr; | MICROSCOPY AND MICROANALYSIS | MICROSC MICROANAL | 1431-9276 | 1435-8115 | 31 | 3 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;MICROSCOPY | 2024 | 3 | 6.2 | 0 | ciliary shortening; renal ischemia-reperfusion; renal tubular cells; scanning electron microscopy | PRIMARY CILIUM; DISTAL TUBULES; KIDNEY; EXPRESSION; CELLS | English | 2025 | 2025-06 | 10.1093/mam/ozaf042 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | Article | Data-driven approach for electricity consumption benchmarking of multi residential buildings | Building energy benchmarking is a crucial process for comparing a building's energy performance with that of others to determine its energy consumption profile and identify potential savings. This approach aims to enhance energy efficiency, provide a foundation for policy development, and encourage conservation efforts. However, current regulatory framework for building energy benchmarking primarily focuses on newly constructed buildings. The complexity of required paperwork and procedures also creates barriers to broader adoption. This study introduces a streamlined, data-driven framework for building energy benchmarking that utilizes publicly available data to simplify the process. Our framework integrates databases encompassing building information, electricity consumption data, and weather data, and incorporates models for predicting monthly electricity consumption and evaluating energy efficiency. By synthesizing these data sources, we developed a predictive model that estimates monthly electricity consumption, producing results that are used to calculate energy use scores and classify buildings into five energy-efficiency grades. We applied this model to evaluate 1,768 buildings in Seoul and Daegu, classifying 235 as Grade 1 (highest efficiency), 728 as Grade 2, 355 as Grade 3, 326 as Grade 4, and 124 as Grade 5 (lowest efficiency). Analysis of buildings with similar specifications in Seoul showed that older buildings tended to have lower energy efficiency than newer constructions, suggesting potential gains from retrofitting and other improvements. This framework, by providing clear explanations of energy efficiency grades and demand predictions, aims to assist building owners, managers, and policymakers in understanding energy performance patterns and identifying opportunities for energy conservation. © 2025 The Authors | Jeun, Woosung; Hwang, Junhwa; Suh, Dongjun; Otto, Marc-Oliver | Department of Convergence and Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Convergence and Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Convergence and Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Mathematics, Natural and Economic Sciences, Ulm University of Applied Sciences, Prittwitzstr, 10, Ulm, 89075, Germany | 59961833400; 57223968394; 36613529600; 57217105369 | dongjunsuh@knu.ac.kr; | Energy and Buildings | ENERG BUILDINGS | 0378-7788 | 1872-6178 | 345 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENERGY & FUELS;ENGINEERING, CIVIL | 2024 | 7.1 | 6.3 | 0 | Benchmarking; Electricity consumption prediction; Energy management; Residential building | Architectural design; Electric power utilization; Energy efficiency; Energy policy; Forecasting; Green buildings; Historic preservation; Housing; Building energy; Building energy performance; Data-driven approach; Electricity consumption prediction; Electricity-consumption; Energy; Energy benchmarking; Energy efficiency grades; Energy-consumption; Residential building; Benchmarking | English | Final | 2025 | 10.1016/j.enbuild.2025.115944 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Concurrent Versus Sequential Adjuvant Capecitabine-Based Chemoradiation in Residual Triple-Negative Breast Cancer After Neoadjuvant-Chemotherapy: A Multicenter Comparative Study | Purpose Given the aggressive nature and poor prognosis of triple-negative breast cancer (TNBC), adjuvant capecitabine has been the standard therapy for residual disease after preoperative systemic therapy (PST). However, the optimal sequence of postoperative radiation therapy (RT) and capecitabine remains unclear. This study evaluated the efficacy and safety of concurrent RT and capecitabine (RT+CAP) versus sequential RT followed by capecitabine (RT -> CAP) in patients with residual TNBC after PST. Methods and Materials In this multicenter retrospective study, data from 491 patients treated at 14 tertiary hospitals were analyzed. The patients received either postoperative RT -> CAP (n = 255) or RT+CAP (n = 236). Survival outcomes were analyzed using the Kaplan-Meier method, and multivariable Cox regression was used to adjust for potential confounders. Results There were no significant differences in the baseline characteristics between the 2 groups. With a median follow-up of 41.8 months, the 4-year rates of disease-free survival (DFS) and overall survival (OS) were 68.8% and 82.4%, respectively. The RT+CAP group demonstrated improvements in DFS (74.6% vs 63.7%, P = .045) and OS (86.8% vs 78.3%, P = .006) compared with the RT -> CAP group. Specifically, RT+CAP showed superior DFS and OS outcomes in patients with a low disease burden (ypT0-1, ypN0/axillar level I only, or Ki67 = grade 2 toxicities and discontinuation of capecitabine because of toxicity did not differ, indicating that RT+CAP was well tolerated. Conclusions RT+CAP offers improvements in oncologic outcomes without an increase in adverse events compared with RT -> CAP, suggesting it is a promising treatment option for patients with residual TNBC after PST. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. | Kim, Nalee; Kim, Su Ssan; Cho, Won Kyung; Park, Won; Chang, Ji Hyun; Kim, Yong Bae; Chang, Ah Ram; Kim, Tae Hyun; Park, Jongmoo; Kim, Jin Hee; Kim, Kyubo; Lim, Yu Jin; Kim, Tae Gyu; Hwa, Jin; Kwon, Jeanny; Kim, Sungmin; Shin, Kyung Hwan; Kim, Haeyoung | Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Radiat Oncol, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Yonsei Univ, Coll Med, Yonsei Canc Ctr, Dept Radiat Oncol, Seoul, South Korea; Soonchunhyang Univ, Seoul Hosp, Dept Radiat Oncol, Seoul, South Korea; Natl Canc Ctr, Res Inst & Hosp, Proton Therapy Ctr, Goyang, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Radiat Oncol, Daegu, South Korea; Keimyung Univ, Dongsan Med Ctr, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Ewha Womans Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Radiat Oncol, Seongnam, South Korea; Kyung Hee Univ, Coll Med, Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Changwon Hosp, Sch Med, Dept Radiat Oncol, Chang Won, South Korea; Chung Ang Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Chungnam Natl Univ, Sch Med, Dept Radiat Oncol, Daejeon, South Korea; Dong A Univ, Dong A Univ Hosp, Coll Med, Dept Radiat Oncol, Busan, South Korea | Kim, Tae Hyun/GNP-3195-2022 | 56714463100; 25627857300; 57201979532; 55663053400; 43860954900; 59722142000; 55261333000; 59326720300; 56180048900; 56441016600; 8213302900; 59502199900; 55696487300; 57213021227; 55888496100; 58722779000; 34873643900; 56007004100 | hykim0131@skku.edu; radiat@snu.ac.kr; | INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | INT J RADIAT ONCOL | 0360-3016 | 1879-355X | 122 | 1 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2024 | 6.5 | 6.4 | 0 | 2025-05-07 | 0 | 1 | RADIOTHERAPY; RADIATION; IRRADIATION; TRIAL | Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm, Residual; Retrospective Studies; Triple Negative Breast Neoplasms; Lung cancer; capecitabine; carboplatin; cyclophosphamide; docetaxel; doxorubicin; pembrolizumab; antineoplastic antimetabolite; capecitabine; Capecitabine; Chemo radiations; Comparatives studies; Disease free survival; Neoadjuvant chemotherapies; Overall survival; Postoperative radiation therapy; Residual disease; Systemic therapy; Triple-negative breast cancers; adult; Article; cancer prognosis; cancer radiotherapy; cancer survival; chemoradiotherapy; comparative study; controlled study; disease burden; disease free survival; drug efficacy; drug safety; female; follow up; hand foot syndrome; human; Kaplan Meier method; lymphedema; major clinical study; middle aged; multicenter study; multiple cycle treatment; nausea and vomiting; neoadjuvant chemotherapy; overall survival; postoperative period; radiation dermatitis; radiation pneumonia; retrospective study; tertiary care center; triple negative breast cancer; adjuvant chemoradiotherapy; adjuvant chemotherapy; adverse event; aged; clinical trial; minimal residual disease; mortality; neoadjuvant therapy; pathology; procedures; therapy; triple negative breast cancer | English | 2025 | 2025-05-01 | 10.1016/j.ijrobp.2024.11.109 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Patient-Reported Outcomes Between Whole-Breast Plus Regional Irradiation and Whole-Breast Irradiation Only in pN1 Breast Cancer After Breast-Conserving Surgery and Taxane-Based Chemotherapy: A Randomized Phase 3 Clinical Trial (KROG 17-01) | Purpose: The role of regional node irradiation (RNI) with whole-breast irradiation (WBI) in patients with pN1 breast cancer receiving taxane-based adjuvant chemotherapy is not well defined. The KROG 1701 trial, a phase 3, multicenter, noninferiority study, aimed to compare the disease-free survival between WBI+RNI and WBI alone in this patient cohort. Comprehensive patient-reported outcomes (PROs) collected at multiple timepoints are reported. Methods and materials: The trial (NCT03269981) enrolled patients with pN1 breast cancer after breast-conserving surgery and taxane-based adjuvant chemotherapy, allocating them to receive either WBI+RNI or WBI only. PROs were assessed using European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaires Core 30and breast cancer-specific module 23 modules at baseline, during radiation therapy, and at subsequent follow-up intervals of 3 to 6 months, and annually up to 4 years. Results: From April 2017 to December 2021, 840 patients were enrolled; 777 received intervention as assigned, and 750 completed baseline PRO questionnaires (387 in WBI+RNI, 363 in WBI only). All PRO domains showed improvements over time (P < .001). During radiation therapy, the WBI+RNI group reported greater fatigue and nausea. Higher arm symptom scores were observed in the WBI+RNI group 3 months post-treatment (P = .030). No other significant PRO domain differences, including arm/breast symptoms, were observed between the 2 groups. Conclusions: In patients with pN1 breast cancer treated with taxane-based chemotherapy, adding RNI to WBI resulted in minor, temporary declines in specific PRO domains, but these differences were not clinically significant. This indicates that overall patient experience between WBI+RNI and WBI is comparable, supporting the safety and patient tolerability of both treatments. | Kim, Nalee; Park, Won; Kim, Haeyoung; Cho, Won Kyung; Ahn, Sung Ja; Kim, Mi Young; Park, Shin-Hyung; Lee, Ik Jae; Ha, Inbong; Kim, Jin Hee; Kim, Tae Hyun; Lee, Kyu Chan; Lee, Hyung-Sik; Kim, Tae Gyu; Shin, Kyung Hwan; Lee, Jong Hoon; Jung, Jinhong; Cho, Oyeon; Kim, Yong Bae; Kim, Eun Seog; Jo, In Young; Koo, Taeryool; Kim, Kyubo; Park, Hae Jin; Shin, Young-Joo; Ha, Boram; Kwon, Jeanny; Lee, Ju Hye; Moon, Sunrock | Sungkyunkwan Univ, Samsung Med Ctr, Dept Radiat Oncol, Sch Med, Seoul, South Korea; Chonnam Natl Univ, Med Sch, Dept Radiat Oncol, Gwangju, South Korea; Kyungpook Natl Univ, Dept Radiat Oncol, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Dept Radiat Oncol, Sch Med, Daegu, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Radiat Oncol, Coll Med, Seoul, South Korea; Gyeongsang Natl Univ, Gyeongsang Natl Univ Hosp, Dept Radiat Oncol, Sch Med, Jinju, South Korea; Keimyung Univ, Dongsan Med Ctr, Sch Med, Sch Med, Daegu, South Korea; Ctr Proton Therapy, Res Inst & Hosp, Ctr Proton Therapy, Goyang 410769, South Korea; Gachon Univ, Gil Med Ctr, Dept Radiat Oncol, Coll Med, Incheon, South Korea; Dong A Univ, Dong A Univ Hosp, Dept Radiat Oncol, Sch Med, Busan, South Korea; Sungkyunkwan Univ, Samsung Changwon Hosp, Dept Radiat Oncol, Sch Med, Chang Won, South Korea; Seoul Natl Univ Hosp, Dept Radiat Oncol, Seoul, South Korea; Catholic Univ Korea, St Vincents Hosp, Dept Radiat Oncol, Suwon, South Korea; Univ Ulsan, Asan Med Ctr, Dept Radiat Oncol, Coll Med, Seoul, South Korea; Ajou Univ, Sch Med, Sch Med, Suwon, South Korea; Yonsei Univ, Yonsei Canc Ctr, Dept Radiat Oncol, Coll Med, Seoul, South Korea; Soonchunhyang Univ, Soonchunhyang Univ Hosp, Dept Radiat Oncol, Coll Med, Cheonan, South Korea; Hallym Univ, Hallym Univ Sacred Heart Hosp, Dept Radiat Oncol, Sacred Heart Hosp,Coll Med, Anyang, South Korea; Ewha Womans Univ, Coll Med, Coll Med, Seoul, South Korea; Hanyang Univ, Dept Radiat Oncol, Coll Med, Seoul, South Korea; Inje Univ, Dept Radiat Oncol, Sanggye Paik Hosp, Seoul, South Korea; Hallym Univ, Dept Radiat Oncol, Dongtan Sacred Heart Hosp, Hwaseong, South Korea; Chungnam Natl Univ Hosp, Dept Radiat Oncol, Daejeon, South Korea; Pusan Natl Univ, Dept Radiat Oncol, Yangsan Hosp, Yangsan, South Korea; Wonkwang Univ, Wonkwang Univ Hosp, Dept Radiat Oncol, Sch Med, Iksan, South Korea; Seoul Natl Univ, Coll Med, Dept Radiat Oncol, Bundang Hosp, Seongnam, South Korea | Park, Shinhyung/LNQ-6428-2024; Kim, Tae Hyun/GNP-3195-2022 | 56714463100; 55663053400; 56007004100; 57201979532; 57211944596; 57204652164; 57203275843; 36786568600; 55446184300; 56441016600; 59326720300; 38163172100; 36071723900; 55696487300; 34873643900; 57201264541; 55855898600; 55657921200; 59722142000; 55261521700; 55558794700; 55598457600; 8213302900; 57201025307; 57114085500; 56022514500; 55888496100; 55648203200; 7401616455 | park@samsung.com; wonro.park@samsung.com; | INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | INT J RADIAT ONCOL | 0360-3016 | 1879-355X | 121 | 2 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2024 | 6.5 | 6.4 | 0 | 2025-05-07 | 0 | 0 | QUALITY-OF-LIFE; RADIATION-THERAPY; NODAL IRRADIATION; ADJUVANT CHEMOTHERAPY; EUROPEAN-ORGANIZATION; RADIOTHERAPY; MULTICENTER; RISK; AXILLA | Adult; Aged; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Lymphatic Irradiation; Mastectomy, Segmental; Middle Aged; Patient Reported Outcome Measures; Quality of Life; Taxoids; Chemotherapy; Diseases; Lung cancer; Oncology; Surgery; aromatase inhibitor; cyclophosphamide; docetaxel; doxorubicin; tamoxifen; taxane derivative; trastuzumab; bridged compound; taxane; taxoid; Adjuvant chemotherapy; Breast Cancer; Breast-conserving surgery; Clinical trial; Disease free survival; Methods and materials; Non-inferiority; Patient-reported outcomes; Taxanes; Whole-breast irradiation; adjuvant chemotherapy; adult; adverse event; arm circumference; arm pain; Article; axillary lymph node dissection; breast cancer; breast radiotherapy; breast-conserving surgery; cancer hormone therapy; cancer radiotherapy; cancer size; cancer survival; cohort analysis; conformal radiotherapy; controlled study; disease free survival; ECOG Performance Status; European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30; fatigue; female; follow up; human; hypofractionated radiotherapy; intensity modulated radiation therapy; invasive ductal breast carcinoma; luminal A breast cancer; luminal B breast cancer; lymph vessel metastasis; lymphedema; major clinical study; mastalgia; middle aged; multicenter study; neoadjuvant chemotherapy; non-inferiority trial; patient-reported outcome; phase 3 clinical trial; quality of life; radiation dose fractionation; radiation sickness; randomized controlled trial; regional node irradiation; sentinel lymph node biopsy; shoulder pain; swelling; tumor volume; whole breast irradiation; adjuvant chemotherapy; aged; breast tumor; clinical trial; disease free survival; drug therapy; partial mastectomy; pathology; radiotherapy; surgery; therapy; Radiotherapy | English | 2025 | 2025-02-01 | 10.1016/j.ijrobp.2024.09.017 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Continuous fixed-bed adsorption of radioactive cesium using PVDF-encapsulated Ti3C2Tx MXene-derived sodium titanate beads | To remove radioactive cesium from aqueous solutions, Ti3C2Tx MXene-derived sodium titanate (MST) was synthesized via in situ alkalization and oxidation and then immobilized in polyvinylidene fluoride (PVDF) polymer. Characterization results confirmed that the MST/PVDF beads exhibit remarkable cesium adsorption performance, attributed to their porous structure, large specific surface area, and diverse surface functional groups. Continuous fixed-bed column experiments were also conducted under various operating parameters, including solution pH, influent cesium concentration, temperature, flow rate, bed height, and competing cations. The dynamic adsorption behavior of cesium was best described by the Thomas and Yoon–Nelson models. Notably, the maximum adsorption capacity of the MST/PVDF beads was determined to be 125.88 mg/g at an influent cesium concentration of 100 mg/L, a flow rate of 0.5 mL/min, and a bed height of 10 cm at pH 7, and 35 °C. This adsorption capacity exceeds those reported in previous studies on column systems, highlighting the material's superior performance. The adsorption process is likely governed by both cation exchange between Na+/H+ and Cs+ ions and electrostatic attraction. Given their unique surface properties and superior cesium adsorption capacity, MST/PVDF beads can offer significant potential for the continuous purification of liquid radioactive waste in practical applications. © 2025 Elsevier Ltd | Lim, Youngsu; Lee, Dae Sung | Department of Environmental Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu, 41566, South Korea; Department of Environmental Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu, 41566, South Korea | 57207112603; 55568524907 | daesung@knu.ac.kr; | Journal of Water Process Engineering | J WATER PROCESS ENG | 2214-7144 | 2214-7144 | 76 | SCIE | ENGINEERING, CHEMICAL;WATER RESOURCES;ENGINEERING, ENVIRONMENTAL | 2024 | 6.7 | 6.5 | 0 | Cesium; Fixed-bed column; MXene; Polyvinylidene fluoride; Sodium titanate | English | Final | 2025 | 10.1016/j.jwpe.2025.108247 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | Development of an amorphous cellulose acetate and Fe-MOF-74 mixed-matrix membrane for the synergistic adsorption and Fenton-based degradation of diclofenac | In the present study, we present an innovative mixed-matrix membrane (MMM) consisting of amorphous cellulose acetate and a metal-organic framework (MOF) for the removal of diclofenac (DCF) from aqueous solutions. Porous and hydrophilic MMMs were fabricated with different weight percentages of the MOF using a facile, non-solvent-induced phase separation process. The synthesized MMMs were then systematically analyzed using various characterization techniques. The optimal MMM with the MOF at 0.7 wt% (CAM-0.7) exhibited a high removal efficiency for DCF (96.0%, k = 0.052/min) via concerted adsorption and Fenton oxidation. Quenching experiments and electron spin resonance tests revealed that this excellent degradation performance was due to the generated center dot OH, 1O2, and O2 center dot- species via H2O2 activation. CAM-0.7 also demonstrated remarkable stability and reusability, with a degradation efficiency of 78.8% after four regeneration cycles. The short- and long-term toxicity of DCF and its intermediates was also predicted using ECOSAR software. Collectively, these findings indicate that the proposed MMM is a promising candidate for the adsorption and advanced oxidation of organic pollutants in water treatment processes. | Njaramba, Lewis Kamande; Yea, Yeonji; Cha, Byungjun; Saravanakumar, Karunamoorthy; Jagan, Govindan; Yoon, Yeomin; Park, Chang Min | Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Ewha Womans Univ, Dept Environm Sci & Engn, 52 Ewhayeodae Gil, Seoul 03760, South Korea | Kamande, Lewis/JLL-5435-2023; Park, Chang Min/CAA-8506-2022 | 57223183206; 57217304205; 57337280900; 57223020778; 57885044400; 7402126688; 57209588953 | yoony@ewha.ac.kr; cmpark@knu.ac.kr; | JOURNAL OF WATER PROCESS ENGINEERING | J WATER PROCESS ENG | 2214-7144 | 72 | SCIE | ENGINEERING, CHEMICAL;WATER RESOURCES;ENGINEERING, ENVIRONMENTAL | 2024 | 6.7 | 6.5 | 0 | 2025-05-07 | 1 | 0 | Mixed-matrix membrane; Cellulose acetate; Fe-MOF-74; Diclofenac; Fenton oxidation | MECHANISM; KINETICS; REMOVAL; MOF-74; WATER | Cellulose acetate; Diclofenac; Fenton oxidation; Fe–MOF-74; Mixed-matrix membrane | English | 2025 | 2025-04 | 10.1016/j.jwpe.2025.107547 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | Article | Integration of optical coherence tomography and intraoral scanning for enhanced subgingival finish line trueness: A comparative analysis | Statement of problem: Intraoral scanning of subgingival finish lines without gingival displacement cords may compromise the accuracy of fixed dental prostheses. The integration of optical coherence tomography (OCT) may overcome this limitation, but further research is required. Purpose: The purpose of this in vitro study was to compare the trueness of scan data obtained from an intraoral OCT system and an IOS for tooth preparations with subgingival finish lines. Material and methods: A maxillary left central incisor was extracted and prepared for a zirconia crown. The prepared tooth was embedded in an artificial gingival model composed of silicone, with a refractive index similar to that of gingival tissue. The subgingival depth of the finish line was standardized between 0.50 and 0.70 mm. Scanning was performed using 4 methods: a CAD reference model (CRM) obtained using a laboratory scanner without gingiva, an IOS (i700; MEDIT) without gingiva (IOSO group), an IOS with artificial gingiva in place (IOSG group), and a dataset integrating OCT scans of the subgingival finish line with IOSG data (OCT group). Each group consisted of 15 specimens (n=15). The CRM dataset was used as the reference, and the best-fit alignment was performed for the IOSO, IOSG, and OCT datasets. The trueness of the finish line was assessed by measuring deviations at predefined points on virtual planes established relative to the CRM data. Additionally, 3-dimensional (3D) trueness was evaluated by calculating deviations across the entire point cloud of the CRM dataset. Statistical analysis was conducted using the Kruskal–Wallis test (α=.05). Results: The IOSO group (median: 12.5 µm; interquartile range [IQR]: 10.5) and the OCT group (median: 17.3 µm; IQR: 16.7) exhibited significantly lower deviations compared with the IOSG group (median: 109.4 µm; IQR: 235.1) (P.05), while the IOSG group exhibited the highest deviation at the finish line (P<.05). Conclusions: The integration of an intraoral OCT system improved the trueness of subgingival finish line scans compared with conventional intraoral scanning with gingival interference. © 2025 Editorial Council for The Journal of Prosthetic Dentistry | Son, KeunBaDa; Lee, Weonjoon; Kim, Kyoung Ho; Jeong, Hyosang; Jeon, Mansik; Kim, Jeehyun; Lee, Kyu-Bok | Research Professor, Advanced Dental Device Development Institute, School of Dentistry, Kyungpook National University, Daegu, South Korea; Ossvis Co., Ltd., Anyang-si, South Korea; Principal Engineer, Huvitz Co., Ltd., Anyang-si, South Korea; Senior Engineer, Huvitz Co., Ltd., Anyang-si, South Korea; School of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu, South Korea; School of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu, South Korea; Department of Prosthodontics, School of Dentistry, Kyungpook National University, Daegu, South Korea | 59709807200; 58183359900; 58183388400; 37561503300; 24171094000; 7601373350; 15925571200 | kblee@knu.ac.kr; | Journal of Prosthetic Dentistry | J PROSTHET DENT | 0022-3913 | 1097-6841 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE | 2024 | 4.8 | 6.5 | 0 | English | Article in press | 2025 | 10.1016/j.prosdent.2025.05.040 | 바로가기 | 바로가기 | 바로가기 | |||||||||||||
| ○ | ○ | Article | Metal-organic framework- or covalent organic framework-derived highly porous carbons: Advantageous adsorptive removal of hazardous organics from water using the carbons, compared to conventional carbons | This review discusses the various preparation methods and physicochemical properties of highly porous carbons derived from metal-organic frameworks (MDCs) or covalent organic frameworks (CDCs). It also explains the roles of physical and chemical activation processes in the preparation of MDCs/CDCs with tailored physicochemical characteristics. The carbonization and activation parameters that control (i) the formation of pores (micropores, mesopores, or macropores), (ii) carbon yield, (iii) the incorporation of heteroatoms (N, S, O, P, metal, etc.), (iii) morphology, and (iv) the hydrophobicity of MDCs/CDCs are explained systematically. Importantly, the physicochemical properties of MDCs/CDCs are compared with those of conventional carbons to highlight the advantages of these materials. Additionally, the applications of MDCs/CDCs in the adsorptive removal of typical hazardous organics, such as pharmaceuticals, personal care products, phenolics, pesticides, dyes, and aromatics from water, are reviewed. The adsorption results are also compared with those of conventional carbons to demonstrate the superior performance of MDCs/CDCs in liquid-phase adsorption. These results are explained in terms of maximum adsorption capacities, adsorption mechanisms, and reusability. Finally, this review provides research outlooks for readers in the relevant fields. | Khan, Nazmul Abedin; Hasan, Zubair; Jhung, Sung Hwa | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Greennano Mat Res Ctr, Daegu 41566, South Korea; East West Univ, Dept Math & Phys Sci, Dhaka 1212, Bangladesh | Jhung, Sung/AAO-6683-2021; Zubair Hasan, MPS/X-2449-2018 | 35170042700; 54079662600; 6701659467 | sung@knu.ac.kr; | JOURNAL OF WATER PROCESS ENGINEERING | J WATER PROCESS ENG | 2214-7144 | 73 | SCIE | ENGINEERING, CHEMICAL;WATER RESOURCES;ENGINEERING, ENVIRONMENTAL | 2024 | 6.7 | 6.5 | 0 | 2025-05-07 | 0 | 0 | Adsorption; Covalent organic framework-derived carbons; Hazardous organics; Metal-organic framework-derived carbons; Pyrolysis | PERSONAL CARE PRODUCTS; ACTIVATED CARBONS; AQUEOUS-SOLUTIONS; BISPHENOL-A; GRAPHENE OXIDE; METHYL-ORANGE; DOPED CARBON; AROMATIC-HYDROCARBONS; EFFICIENT ADSORBENT; NANOPOROUS CARBON | Adsorption; Covalent organic framework-derived carbons; Hazardous organics; Metal–organic framework-derived carbons; Pyrolysis | English | 2025 | 2025-05 | 10.1016/j.jwpe.2025.107656 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Nonradical activation of periodate by nano-TiO2 embedded multi-walled carbon nanotubes for effective decolorization of selected organic dyes | The catalytic activation of periodate (PI) via heterogeneous systems employing carbon nanotubes (CNTs) has demonstrated efficacy in degrading aquatic recalcitrant contaminants. However, the underlying reaction mechanisms remain controversial, and structural modifications to optimize electron transfer efficiency are underexplored. This study investigates the removal of four organic dyes (Acid Blue 80, Crystal Violet, Methylene Blue (MB), and Reactive Black 5) through periodate activation via multi-walled carbon nanotubes (MWCNT) incorporating nanoparticulate TiO2 within their internal channels (TiO2@MWCNT, TCNT). Within a 60-min reaction, the system achieved over 90 % decolorization of MB (10 mg/L initial). A series of spectroscopic approaches, including the use of inhibitors (e.g., methanol, furfuryl alcohol, and sodium azide), electron paramagnetic resonance spectroscopy analyses, and electrochemical experiments, revealed that a nonradical mechanism (i.e., electron transfer) might be responsible for the degradation of organic dyes. Notably, TiO2 encapsulation within MWCNT channels facilitated accelerated electron transfer from organic dyes to PI, enhancing degradation kinetics by 1.4-fold compared to unmodified MWCNT. The effects of varying initial pH and the presence of chloride, bicarbonate, and humic acid on MB removal were systematically evaluated. The TCNT/PI system exhibited stable catalytic performance across five consecutive degradation cycles, with detailed analysis revealing MB degradation pathways and intermediate products. Overall, these findings suggest that introducing semiconductors into the inner channels of MWCNT may serve as a strategic catalyst design option to increase the treatment efficiency of emerging micropollutants. | Kim, Hak-Hyeon; Kim, Tae Hyeong; An, Sujin; Byun, Seoyeon; Kim, Seoni; Lee, Changha; Park, Chang Min; Jang, Min; Lee, Seunghyun; Yoon, Yeomin | Ewha Womans Univ, Dept Environm Sci & Engn, Seoul 03760, South Korea; Hanyang Univ ERICA, Dept Appl Chem, Ansan 15588, South Korea; Hanyang Univ ERICA, Ctr Bionano Intelligence Educ & Res, Ansan 15588, South Korea; Seoul Natl Univ, Inst Chem Proc ICP, Inst Engn Res, Sch Chem & Biol Engn, Seoul 08826, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kwangwoon Univ, Dept Environm Engn, 20 Kwangwoon Ro, Seoul 01897, South Korea; Hanyang Univ ERICA, Dept Energy & Bio Sci, Ansan 15588, South Korea | Park, Chang Min/CAA-8506-2022 | 56683717600; 57216457235; 59162816100; 59920059500; 55816940100; 57857358000; 57209588953; 36762550700; 58376516400; 7402126688 | leeshyun@hanyang.ac.kr; yoony@ewha.ac.kr; | JOURNAL OF WATER PROCESS ENGINEERING | J WATER PROCESS ENG | 2214-7144 | 75 | SCIE | ENGINEERING, CHEMICAL;WATER RESOURCES;ENGINEERING, ENVIRONMENTAL | 2024 | 6.7 | 6.5 | 0 | 2025-06-11 | 0 | 0 | Organic dyes; Nonradical; Carbon nanotubes; Periodate; Oxidation; Organic dyes; Nonradical; Carbon nanotubes; Periodate; Oxidation | PHOTOACTIVATED PERIODATE; METAL NANOPARTICLES; METHYLENE-BLUE; SINGLET OXYGEN; RATE CONSTANTS; DEGRADATION; OXIDATION; PEROXYMONOSULFATE; PERSULFATE; MECHANISM | Carbon nanotubes; Nonradical; Organic dyes; Oxidation; Periodate | English | 2025 | 2025-06 | 10.1016/j.jwpe.2025.108020 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | Article | Positional accuracy of intraoral scan alignment to a facial scan using structured light scanning and trial denture base with occlusal rim markers in patients with complete maxillary edentulism | Statement of problem: Creating precise 3D virtual head models for patients with complete maxillary edentulism remains challenging owing to the lack of natural landmarks and limitations of current image-matching technologies. Purpose: The purpose of this study was to evaluate the positional accuracy of intraoral scan alignment to structured light-based facial scans using varying sizes and positions of occlusal rim markers under maxillary edentulous conditions. Material and methods: Radiopaque artificial markers of 3 sizes (2, 4, and 6 mm) were made and attached to the maxillary occlusal rim of a completely edentulous patient at different positions (midline-canine [MC], midline [M], canine [C]). Facial scans were obtained of the patient by using a structured light facial scanner under 9 experimental conditions (size-location: 2MC, 2M, 2C, 4 MC, 4M, 4C, 6MC, 6M, and 6C; 5 scans under each condition). Intraoral scans were aligned to the facial scans using stepwise images matching the occlusal rim scan casts. The alignment accuracy was evaluated by comparing the intraoral scan with a reference position established using cone beam computed tomography data. Measured variables included anterior and posterior linear deviations and angular deviation of the arch plane. Statistical analysis was conducted using the Kruskal–Wallis test and Mann–Whitney U test with Bonferroni correction (α=.05). Results: The 4-mm and 6-mm marker groups exhibited significantly lower deviation in image registration than the groups without markers and those with 2-mm markers (P<.001). Regarding the marker position, the midline-canine group exhibited the lowest deviation value, followed by the midline and canine groups. Markers positioned in the midline exhibited less deformation compared with those in the canine region. Conclusions: Occlusal rim markers can be used to align intraoral and facial scans in patients with complete maxillary edentulism when structured light face scanning is included. Markers with a clearly recognizable size in facial scans are less prone to deformation in the facial midline area. © 2025 | Lee, Du-Hyeong; Win, Thaw Thaw; Mai, Hang-Nga; Seo, Sang-Hyeok; Cho, Seok-Hwan | Department of Prosthodontics, University of Iowa College of Dentistry and Dental Clinics, Iowa City, Iowa; School of Dentistry, Kyungpook National University, Daegu, South Korea; Graduate student, Department of Prosthodontics, School of Dentistry, Kyungpook National University, Daegu, South Korea; Research Professor, Institute for Translational Research in Dentistry, Kyungpook National University, Daegu, Republic of Korea; Dental School, Hanoi University of Business and Technology, Hanoi, Viet Nam; Graduate student, Department of Prosthodontics, School of Dentistry, Kyungpook National University, Daegu, South Korea; Department of Prosthodontics, University of Iowa College of Dentistry and Dental Clinics, Iowa City, IA, United States | 35770948000; 58157726100; 59868813700; 59865132400; 12780626400 | seokhwan-cho@uiowa.edu; | Journal of Prosthetic Dentistry | J PROSTHET DENT | 0022-3913 | 1097-6841 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE | 2024 | 4.8 | 6.5 | 0 | 2025-06-11 | 0 | English | Article in press | 2025 | 10.1016/j.prosdent.2025.04.016 | 바로가기 | 바로가기 | 바로가기 |
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