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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Tailoring nanostructured NbCoSn-based thermoelectric materials via crystallization of an amorphous precursor Tailoring nanostructures is nowadays a common approach for enhancing the performance of thermoelectric Heusler compounds by decreasing the thermal conductivity without significantly affecting the electrical conductivity. However, the most widely reported method for obtaining nanostructured thermoelectrics, an approach based on crushing as-cast alloy ingots followed by sintering of the debris, only gives limited control of the final nanostructure due to residual elemental segregation after casting. Here, a novel approach for fabricating nanostructured Heusler compounds is presented, which is based on crystallizing an amorphous precursor of NbCo1.1Sn composition. This method yields two distinct nanostructures, namely one comprising only halfHeusler grains and another one comprising half-Heusler grains and full-Heusler nano-precipitates. The latter sample exhibits enhanced negative Seebeck coefficients as compared to the former over a wide temperature range. Using advanced characterization techniques, such as high-resolution transmission electron microscopy and atom probe tomography, in conjunction with ab initio density functional theory, detailed insights into the nanostructure and electrical properties of the specimens are provided. Filtering of low energy and mobility electrons at the half-Heusler and full-Heusler interface along with the formation of Co interstitial defects in the half-Heusler matrix are proposed to be the possible causes for the enhanced Seebeck coefficient of the nano precipitate containing specimen. Jung, Chanwon; Dutta, Biswanath; Dey, Poulumi; Jeon, Seong-jae; Han, Seungwoo; Lee, Hyun-Mo; Park, Jin-Seong; Yi, Seong-Hoon; Choi, Pyuck-Pa Korea Adv Inst Sci & Technol KAIST, Dept Mat Sci & Engn, 291 Daehak Ro, Daejeon 34141, South Korea; Delft Univ Technol, Dept Mat Sci & Engn, Mekelweg 2, NL-2628 CD Delft, Netherlands; Korea Inst Machinery & Mat KIMM, Dept Nano Mech, 156 Gajeongbuk Ro, Daejeon 34103, South Korea; Hanyang Univ, Div Mat Sci & Engn, 222 Wangsimni Ro, Seoul 04763, South Korea; Kyungpook Natl Univ, Dept Mat Sci & Met Engn, 80 Daehakro, Daegu 41566, South Korea Yi, Seonghoon/HGC-6912-2022; Park, Jin-Seong/U-7124-2018; Dey, Poulumi/ABD-0303-2022; Choi, Pyuck-Pa/B-9012-2016; Jung, Chanwon/GOE-5784-2022 57195481133; 7102128659; 57217846544; 35782985300; 55682590600; 56779260800; 8044372500; 14008383000; 8085506500 yish@knu.ac.kr;p.choi@kaist.ac.kr; NANO ENERGY NANO ENERGY 2211-2855 2211-3282 80 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED 2021 19.069 5.1 1.41 2025-07-30 29 28 Thermoelectric; Nanocrystallization; Atom probe tomography; Density functional theory HALF-HEUSLER; ALLOYS; PERFORMANCE; SCALE; SKUTTERUDITE; TEMPERATURE; THERMOPOWER; SCATTERING Atom probe tomography; Density functional theory; Half–Heusler compound; Nanocrystallization; Thermoelectric Cobalt alloys; Cobalt metallography; Density functional theory; High resolution transmission electron microscopy; Metal castings; Niobium alloys; Niobium metallography; Seebeck coefficient; Sintering; Ternary alloys; Thermal conductivity; Thermoelectricity; Tin alloys; Tin metallography; Ab initio density functional theories (DFT); Atom probe tomography; Characterization techniques; Electrical conductivity; Elemental segregation; Interstitial defects; Thermo-Electric materials; Wide temperature ranges; Nanostructures English 2021 2021-02 10.1016/j.nanoen.2020.105518 바로가기 바로가기 바로가기 바로가기
Article Temperature dependence of the piezotronic effect in CdS nanospheres We used simple graphene transfer and microwave synthesis to deposite wurtzite-structured CdS nanospheres with gold nanoparticles (AuNPs) on a flexible polyethylene terephthalate (PET) substrate. The temperature dependence of the piezotronic effect of the CdS nanospheres was studied in the temperature range 240-320 K under tensile strains of 0.00-0.40%, the effect was found to significantly depend on the device temperature. Moreover, the piezotronic effect was enhanced by over 590% at a strain of 0.40% by cooling temperature owing to the improved efficiency of piezoelectric potential charges. This is a result of the decreased screening effect by reduced carrier generation in the CdS. In addition, the consistent charge transfer mechanism in the investigated piezotronic device is explained by the possible energy band diagrams. The results of this analysis provide a comprehensive understanding of the piezotronic effect and provide a direction for future device applications in fields such as health monitoring, human-machine communication, surgical robotics, and artificial intelligence. Puneetha, Peddathimula; Mallem, Siva Pratap Reddy; Bathalavaram, Poornaprakash; Lee, Jung-Hee; Shim, Jaesool Yeungnam Univ, Sch Mech Engn, Gyongsan 38541, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Gangneung Wonju Natl Univ, Dept Elect Engn, Kangnung 25457, South Korea 56354594100; 55422639100; 53064430100; 57196140713; 16040548500 drmspreddy@knu.ac.kr;drpoornaphy@gmail.com;jshim@ynu.ac.kr; NANO ENERGY NANO ENERGY 2211-2855 2211-3282 84 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED 2021 19.069 5.1 1.02 2025-07-30 25 25 Flexible PET; CdS nanosphere; Graphene layer; Piezotronic effect; Screening effect PIEZO-PHOTOTRONICS; SENSOR; BEHAVIOR; MOS2; PET CdS nanosphere; Flexible PET; Graphene layer; Piezotronic effect; Screening effect Cadmium sulfide; CdS nanoparticles; Charge transfer; Frequency response; Gold nanoparticles; Graphene; Nanospheres; Plastic bottles; Strain; Synthesis (chemical); Temperature distribution; Zinc sulfide; CdS; CdS nanosphere; Flexible polyethylene terephthalate; Gold nanoparticle; Graphene layers; Microwave synthesis; Piezotronic effect; Screening effect; Simple++; Temperature dependence; II-VI semiconductors English 2021 2021-06 10.1016/j.nanoen.2021.105923 바로가기 바로가기 바로가기 바로가기
Article Ultra-magnetic field sensitive magnetoelectric composite with sub-pT detection limit at low frequency enabled by flash photon annealing An ultra-sensitive magnetic field detector is demonstrated in a bilayer magnetoelectric (ME) composite structure employing a flash photon annealing (FPA) treated amorphous Metglas (FeBSi) alloy and piezoelectric single crystal macro fiber composites (SFC). A millisecond FPA annealing approach altered the magnetostrictive and mechanical properties of Metglas by annealing at a high temperature without inducing severe embrittlement. The ME composite (MEC) fabricated with FPA-treated Metglas (FPA-MEC) exhibited an enhanced ME coupling coefficient (at a resonance condition -47% and at an off-resonance condition -52%) relative to that of untreated Metglas based ME composite (pristine MEC), owing to the improved magnetic flux concentration/piezo-magnetic coefficient and reduced resonance loss in Metglas. This led to the realization of an ultra-sensitive magnetic field sensor with a direct detection limit of 0.5 pT [1 order improved performance compared to the pristine MEC (sensing limit of 5 pT)] at an extremely low resonance frequency condition (< 100 Hz). The obtained results demonstrate a feasible way to design magnetic sensors for detecting bio-magnetic and extremely low-frequency (ELF) magnetic fields under ambient conditions. Peddigari, Mahesh; Woo, Kyoohee; Kim, Sung-Dae; Kwak, Min Sub; Jeong, Jae Won; Kang, Jee-Hyun; Lee, Seung-Hyun; Park, Jung Hwan; Park, Kwi-Il; Annapureddy, Venkateswarlu; Jang, Jongmoon; Min, Yuho; Ahn, Cheol-Woo; Choi, Jong-Jin; Hahn, Byung-Dong; Yoon, Woon-Ha; Ryu, Jungho; Hwang, Geon-Tae Korea Inst Mat Sci KIMS, 797 Changwondaero, Chang Won 51508, Gyeongnam, South Korea; Korea Inst Machinery & Mat KIMM, Nanoconvergence Mfg Syst Res Div, Daejeon 305343, South Korea; Yeungnam Univ, Sch Mat Sci & Engn, Gyongsan 38541, Gyeongbuk, South Korea; Kumoh Natl Inst Technol, Dept Aeronaut Mech & Elect Convergence Engn, Dept Mech Engn, 61 Daehak Ro, Gumi 39177, Gyeongbuk, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, 80 Daehak Ro, Daegu 41566, South Korea; Natl Inst Technol, Dept Phys, Tiruchirappalli 620015, Tamil Nadu, India; Pukyong Natl Univ, Dept Mat Sci & Engn, Busan 42601, South Korea Woo, Kyoohee/J-8686-2014; Choi, Jong-Jin/D-3396-2009; Annapureddy, Venkateswarlu/A-1540-2016; Ryu, Jungho/LXU-4081-2024; Park, Kwiil/LKN-9445-2024; Han, Guifang/AAS-5700-2020; Kang, Jee-Hyun/ABB-7578-2020 56316365700; 23986718500; 56373258800; 57203753285; 56540094000; 55698467300; 57207067458; 55716954000; 35280874200; 55511875200; 55851287300; 36782804100; 7201986655; 57199099597; 10639824200; 15833577200; 57201603501; 36704574900 jhryu@ynu.ac.kr;gthwang@pknu.ac.kr; NANO ENERGY NANO ENERGY 2211-2855 2211-3282 90 SCIE CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED 2021 19.069 5.1 1.18 2025-07-30 32 32 Magnetoelectric; Nanocrystallization; Magnetic sensitivity; Limit of detection; Flash photon annealing (FPA) METALLIC GLASSES; LAMINATE COMPOSITE; SENSORS; ALLOY Flash photon annealing (FPA); Limit of detection; Magnetic sensitivity; Magnetoelectric; Nanocrystallization Crystal structure; Iron alloys; Magnetic fields; Magnetic sensors; Photons; Resonance; Silicon alloys; Single crystals; Detection limits; Flash photon annealing; Limit of detection; Magnetic sensitivity; Magnetoelectric composites; Magnetoelectrics; ME composites; Nanocrystallisation; Resonance condition; Ultrasensitive; Annealing English 2021 2021-12 10.1016/j.nanoen.2021.106598 바로가기 바로가기 바로가기 바로가기
Article (−)-Tetrahydroberberrubine∙acetate accelerates antioxidant potential and inhibits food associated Bacillus cereus in rice A protoberberine alkaloid, (−)-tetrahydroberberrubine∙acetate (THBA) was assessed for its antioxidant potential and ability to inhibit the growth of a food hazard bacterium Bacillus cereus in vitro and in situ. THBA displayed significant and dose-dependent cellular antioxidant potential against hydrogen peroxide-induced oxidative stress in NIH 3T3 fibroblast cells and decreased the ROS levels as well as increased the expression levels of SOD1 and SOD2 enzymes. The inhibitory spectrum of THBA confirmed its mechanistic role in the disruption of the membrane integrity of B. cereus as evidenced by the results of time-inactivation, cell membrane integrity, NPN membrane uptake, membrane potential, and electron microscopy analyses. Moreover, THBA inhibited biofilm formation by B. cereus and disrupted pre-established biofilms on a glass surface. Furthermore, THBA was also able to inhibit B. cereus in raw rice with a significant amount of reduction in CFU counts, suggesting its potential role as a natural antioxidant and antimicrobial agent. © 2020 Elsevier Ltd Bajpai, Vivek K.; Park, InWha; Khan, Imran; Alshammari, Fanar Hamad; Kumar, Pradeep; Chen, Lei; Na, MinKyun; Huh, Yun Suk; Han, Young-Kyu; Shukla, Shruti Department of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul, 04620, South Korea; College of Pharmacy, Chungnam National University, Daejeon, 34134, South Korea, Natural Product Informatics Research Center, Korea Institute of Science and Technology (KIST), Gangneung Institute, Gangneung, 25451, South Korea; Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, South Korea, The Hormel Institute, University of Minnesota, Austin, 55912, MN, United States; Department of Food Science and Biotechnology, Graduate School, Kyungpook National University, Daegu, 41566, South Korea; Department of Forestry, North Eastern Regional Institute of Science and Technology, Nirjuli, 791109, Arunachal Pradesh, India; College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, China; College of Pharmacy, Chungnam National University, Daejeon, 34134, South Korea; Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, South Korea; Department of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul, 04620, South Korea; Department of Food Science and Technology, National Institute of Food Technology Entrepreneurship and Management (NIFTEM), Sonipat, 131028, Haryana, India 15753535700; 57195484915; 56707589700; 57191860948; 57212043589; 56945876100; 7006636995; 8425039200; 7404096707; 26634567200 chenlei841114@hotmail.com; Food Chemistry FOOD CHEM 0308-8146 1873-7072 339 SCIE CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS 2021 9.231 5.2 1.03 2025-07-30 18 (­−)-Tetrahydroberberrubine∙acetate; Antioxidant, Bacillus cereus; Biofilm inhibition; Food rice model; Scanning electron microscopy (SEM); Transmission electron microscopy (TEM) Alkaloids; Animals; Anti-Infective Agents; Antioxidants; Bacillus cereus; Berberine; Biofilms; Cell Survival; Food Microbiology; Mice; NIH 3T3 Cells; Oryza; Reactive Oxygen Species; Superoxide Dismutase-1; Ultraviolet Rays; Antimicrobial agents; Antioxidants; Bacteriology; Biofilms; Cell culture; Food microbiology; acetic acid; beroline; copper zinc superoxide dismutase; hydrogen peroxide; manganese superoxide dismutase; reactive oxygen metabolite; tetrahydroberberrubine; unclassified drug; alkaloid; antiinfective agent; antioxidant; berberine; tetrahydroberberrubine; Antioxidant potential; Biofilm formation; Electron microscopy analysis; Inhibitory spectrums; Membrane integrity; Membrane potentials; Natural antioxidants; Protoberberine alkaloids; antioxidant activity; Article; Bacillus cereus; bacterial cell; bacterial count; bacterial growth; bacterial membrane; biofilm; broth dilution; carbon nuclear magnetic resonance; cell membrane; cell structure; comparative study; controlled study; Cronobacter sakazakii; cytotoxicity; electron microscopy; Escherichia coli O157:H7; fluorescence intensity; fluorescence microscopy; in vitro study; membrane depolarization; membrane potential; MTT assay; NIH 3T3 cell line; nonhuman; oxidative stress; protein expression level; proton nuclear magnetic resonance; Pseudomonas aeruginosa; rice; Salmonella enterica serovar Typhimurium; animal; Bacillus cereus; cell survival; chemistry; drug effect; food control; metabolism; microbiology; mouse; Oryza; physiology; radiation response; ultraviolet radiation; Bacillus cereus English Final 2021 10.1016/j.foodchem.2020.127902 바로가기 바로가기 바로가기
Article Adsorption and desorption characteristics of a phenolic compound from Ecklonia cava on macroporous This study aimed to develop efficient adsorption and desorption processes to purify phenolic compounds from Ecklonia cava. We compared the adsorption and desorption properties of five resins. HP2MG showed the highest adsorption and desorption capacities and adsorption rate; hence, it was selected for phenolic compound purification. Adsorption isotherm parameters indicated favorable adsorption between HP2MG and phenolic compounds. Thermodynamic parameters showed that the absorption process physically proceeded. In the dynamic adsorption process, adsorption property was assessed based on bed length (4-10 cm) and flow rate (1.64-3.27 mL/min). The breakthrough point increased with increased bed length and decreased adsorption flow rate. However, the high desorption flow rate shortened the processing time. The phenolic contents, antiglycation activity and antioxidant activity of the extract were measured before and after purification. The dieckol and phlorofucofuroeckol-A increased three times after purification. The purified extract showed higher anti-glycation and antioxidant activities than the extract. Park, Jong Jin; Lee, Won Young Kyungpook Natl Univ, Sch Food Sci & Technol, Daegu 41566, South Korea Lee, Wonyoung/AAL-2780-2021; Park, Jongjin/AAL-3484-2021 58602432200; 57195940408 wonyoung@knu.ac.kr; FOOD CHEMISTRY FOOD CHEM 0308-8146 1873-7072 338 SCIE CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS 2021 9.231 5.2 4.32 2025-07-30 73 75 Adsorption; Ecklonia cava; Macroporous resin; Phenolic compound PHLOROTANNINS; PURIFICATION; SEPARATION; ACID; ANTHOCYANINS; RESINS; EQUILIBRIUM; FLAVONOIDS; GLYCATION; PRODUCTS Adsorption; Ecklonia cava; Macroporous resin; Phenolic compound Adsorption; Phaeophyta; Phenols; Porosity; Resins, Synthetic; Thermodynamics; Antioxidants; Desorption; Glycosylation; Phenols; Purification; Resins; algal extract; aminoguanidine; ascorbic acid; dieckol; Ecklonia cava extract; phenol derivative; phlorofucofuroeckol A; resin; unclassified drug; phenol derivative; resin; Absorption process; Adsorption and desorptions; Adsorption properties; Anti-oxidant activities; Breakthrough point; Dynamic adsorption; Phenolic compounds; Thermodynamic parameter; absorption; ABTS radical scavenging assay; adsorption; adsorption kinetics; antioxidant activity; Article; desorption; DPPH radical scavenging assay; Ecklonia cava; flow rate; food processing; glycation; high performance liquid chromatography; nonhuman; physical chemistry; porosity; purification; surface area; thermodynamics; adsorption; brown alga; chemistry; isolation and purification; Adsorption English 2021 2021-02-15 10.1016/j.foodchem.2020.128150 바로가기 바로가기 바로가기 바로가기
Article Barrier protective functions of hederacolchiside-E against HMGB1-mediated septic responses The role of high mobility group box 1 (HMGB1) has been recognized as important, and suppression of HMGB1 release and restoration of vascular barrier integrity are regarded as potentially promising therapeutic strategies against sepsis. Hederacolchiside-E (HCE), namely 3-O-{alpha-L-rhamnopyranosyl (1 -> 2)-[beta-D-glucopyranosyl(1 -> 4)]-alpha-L-arabinopyranosyl}-28-O-[alpha-L-rhamnopyranosyl (1 -> 4)-beta-D-glucopyranosyl(1 -> 6)-beta-D-glucopyranosyl ester, is a bidesmosidic oleanane saponin first isolated in 1970 from the leaves of Hedera colchica. We tested our hypothesis that HCE inhibits HMGB1-induced vascular hyperpermeability and thereby increases the survival of septic mouse model from suppression of HMGB1 release upon lipopolysaccharide (LPS)-stimulation. In LPS-activated human endothelial cells and a sepsis mouse model by cecal ligation and puncture (CLP), antiseptic activity of HCE was investigated from suppression of vascular permeability, pro-inflammatory proteins, and tissue injury markers. Post-treatment of HCE significantly suppressed HMGB1 release both in LPS-activated human endothelial cells and the CLP-induced sepsis mouse model. HCE inhibited hyperpermeability and alleviated HMGB1-mediated vascular disruptions, and reduced sepsis-related mortality and tissue injury in mice. Our results suggest that reduction of HMGB1 release and septic mortality by HCE may be useful for the drug candidate of sepsis, indicating a possibility of successful repositioning of HCE. Lee, Wonhwa; Choi, Hui-Ji; Sim, Hyunchae; Choo, Samyeol; Song, Gyu Yong; Bae, Jong-Sup Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, BK21 Plus KNU Multi Based Creat Drug Res Team,CMR, Daegu 41566, South Korea; Korea Res Inst Biosci & Biotechnol, Aging Res Ctr, Daejeon 34141, South Korea; Chungnam Natl Univ, Coll Pharm, 99 Daehak Ro, Daejon 34134, South Korea Lee, Wonhwa/GLQ-6506-2022; Bae, Jong-Sup/AAU-9724-2020 50161632800; 57220585937; 57219098739; 57219092520; 7402253074; 16021543200 gysong@cnu.ac.kr;baejs@knu.ac.kr; PHARMACOLOGICAL RESEARCH PHARMACOL RES 1043-6618 163 SCIE PHARMACOLOGY & PHARMACY 2021 10.334 5.2 0.56 2025-07-30 6 7 Hederacolchiside-E; HMGB1; Endothelium; Sepsis NF-KAPPA-B; GROUP BOX 1; IMPROVES SURVIVAL; HEDERASAPONIN-C; ALPHA-HEDERIN; PROTEIN HMGB1; ZINGERONE; CELLS; LIPOPOLYSACCHARIDE; PHOSPHORYLATION Endothelium; Hederacolchiside-E; HMGB1; Sepsis Acute Lung Injury; Animals; Capillary Permeability; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cytokines; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Saponins; Sepsis; Sirtuin 1; endothelial leukocyte adhesion molecule 1; hederacolchiside E; high mobility group B1 protein; immunoglobulin enhancer binding protein; intercellular adhesion molecule 1; interleukin 1beta; interleukin 6; lipopolysaccharide; mitogen activated protein kinase 1; mitogen activated protein kinase p38; plant medicinal product; toll like receptor 2; toll like receptor 4; tumor necrosis factor; unclassified drug; vascular cell adhesion molecule 1; zingerone; cell adhesion molecule; cytokine; hederacolchiside E; high mobility group B1 protein; immunoglobulin enhancer binding protein; lipopolysaccharide; saponin; sirtuin 1; animal cell; animal experiment; animal model; animal tissue; antiinflammatory activity; antisepsis; Article; blood vessel permeability; cecal ligation and puncture-induced sepsis; cell adhesion; cell migration; cell viability assay; controlled study; endothelium cell; enzyme linked immunosorbent assay; enzyme repression; high performance liquid chromatography; histopathology; human; human cell; male; mortality rate; mouse; MTT assay; neutrophil; nonhuman; priority journal; protein expression; protein synthesis; treatment outcome; treatment response; Western blotting; acute lung injury; animal; C57BL mouse; capillary permeability; cell motion; drug effect; MAPK signaling; metabolism; physiology; sepsis; umbilical vein endothelial cell English 2021 2021-01 10.1016/j.phrs.2020.105318 바로가기 바로가기 바로가기 바로가기
Article Effects of position-triggered electrical stimulation on poststroke hemiparetic shoulder subluxation BACKGROUND: Shoulder subluxation is a frequent complication after stroke causing joint instability, shoulder pain, decreased activities of daily living, and impedance to rehabilitation progress. Electrical stimulation (ES) is considered an effective modality to reduce shoulder subluxation in acute stroke. However, few studies have investigated the effect of position-triggered ES, which induces active muscle contraction though accurate motion detection. AIM: The aim of this study was to investigate whether position-triggered ES was more effective in reducing acute hemiplegic shoulder subluxation after stroke than passive ES. DESIGN: Single-blind, randomized controlled trial. SETTING: The study setting was the university hospital rehabilitation center. POPULATION: Fifty poststroke subacute hemiparetic patients with shoulder subluxation. METHODS: Patients were randomly assigned into two groups. The position-triggered ES group received 30-minute ES sessions, 5 days per week for 3 weeks with specially modified Novastim (R) CU-FSI (CU Medical Systems, Inc., Gangwon-do, South Korea) for motion triggering. The passive ES group received the same protocol without motion triggering. The vertical distance (VD) and the joint distance (JD), relative VD and JD (rVD, rJD), upper extremity component of Fugl-Meyer Motor Assessment (FMA(upper)), Motricity Index (MI), Manual Function Test (MFT), and peak torque of affected shoulder abductor (PT) were assessed at baseline (T0), end of electrical stimulation session (T1), and 3 weeks (T2) after treatment. RESULTS: Repeated-measures analysis of variance revealed significant interaction between time and intervention on JD and rJD, indicating that shoulder subluxation was significantly more reduced in position-triggered ES than in passive ES (P<0.05). However, FMA(upper), MI, MFT, and PT did not show this significance. The change of (Delta)JD, Delta rVD, and Delta rJD in the motion-triggered ES group improved significantly more at T1 than in the passive ES group (P<0.05). This significant improvement was not seen at T2. CONCLUSIONS: Position-triggered ES may be more effective than passive ES in improving poststroke shoulder subluxation; however, this effect was not maintained after the withdrawal of stimulation. CLINICAL REHABILITATION IMPACT: Position-triggered ES may be useful to reducing poststroke shoulder subluxation. Hong, Juntaek; Jung, Taemin; Kim, Aeryoung; Choi, Hyoseon; Lee, Sunmi; Kim, Deogyoung Yonsei Univ, Dept Rehabil Med, Coll Med, Seoul, South Korea; Yonsei Univ, Res Inst Rehabil Med, Coll Med, Seoul, South Korea; Yonsei ROI Rehabil Clin, Seoul, South Korea; Kyungpook Natl Univ, Dept Phys Med & Rehabil, Daegu, South Korea; Eulji Univ, Nowon Eulji Med Ctr, Dept Rehabil Med, Sch Med, Seoul, South Korea ; kim, deog young/Q-8498-2019 57209323242; 56684106800; 57196257330; 57212190746; 57389203600; 55375583000 kimdy@yuhs.ac; EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE EUR J PHYS REHAB MED 1973-9087 1973-9095 57 5 SCIE REHABILITATION 2021 5.313 5.2 0.75 2025-07-30 5 5 Stroke; Electrical stimulation; Shoulder dislocation GLENOHUMERAL SUBLUXATION; UPPER EXTREMITY; STROKE PATIENTS; ELECTROMYOGRAPHY; HEMIPLEGIA; PAIN; RELIABILITY; PREVENTION; RECOVERY; VALIDITY Electrical stimulation; Shoulder dislocation; Stroke English 2021 2021-10 10.23736/s1973-9087.21.06639-9 바로가기 바로가기 바로가기 바로가기
Article MIMO Design for Internet of Things: Joint Optimization of Spectral Efficiency and Error Probability in Finite Blocklength Regime In this article, we consider a multiple-input-multiple-output (MIMO) system serving Internet of Things (IoT) devices. To satisfy stringent requirements on the latency of IoT communications, the IoT devices communicate in the finite blocklength regime, wherein the achievable spectral efficiency (SE) has a backoff factor and decoding error probability is nonnegligible. Aiming to jointly optimize the sum SE and the maximum error probability, we first express the achievable SE as a function of the channel coefficients, precoders, and error probabilities. Subsequently, we formulate a problem with respect to precoders and error probabilities. A straightforward approach for the formulated problem, however, is challenging as it not only has multiple objectives but also is nonconvex. To resolve these issues, we first transform the problem as a single-objective optimization by using a weighted sum approach. Based on the reformulation, we propose an algorithm, in which error probabilities and precoders are determined by alternating two phases. Via simulations, we demonstrate that the proposed method offers significant gains compared to baseline methods, in terms of the achievable SE and the maximum error probability. In particular, we show that the communication latency is greatly reduced by using the proposed method. Choi, Jinseok; Park, Jeonghun Ulsan Natl Inst Sci & Technol, Dept Elect Engn, Ulsan 44919, South Korea; Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 41566, South Korea Choi, Jinseok/AAL-6383-2020 57190581671; 57853652900 jinseokchoi@unist.ac.kr;jeonghun.park@knu.ac.kr; IEEE INTERNET OF THINGS JOURNAL IEEE INTERNET THINGS 2327-4662 8 20 SCIE COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS 2021 10.238 5.2 0.7 2025-07-30 13 14 Error probability; MIMO communication; Optimization; Decoding; Reliability; Measurement; Internet of Things; Finite blocklength; Internet of Things (IoT); latency; multiobjective optimization; multiple-input-multiple-output (MIMO) SUM-RATE; DOWNLINK; ALLOCATION Finite blocklength; Internet of Things (IoT); latency; multiobjective optimization; multiple-input-multiple-output (MIMO) Efficiency; Errors; MIMO systems; Probability; Channel coefficient; Communication latency; Finite blocklength regimes; Internet of Things (IOT); Single objective optimization; Spectral efficiencies; Stringent requirement; Weighted sum approaches; Internet of things English 2021 2021-10-15 10.1109/jiot.2021.3073239 바로가기 바로가기 바로가기 바로가기
Article Origin of low thermal conductivity in Nb1-xTixFe1.02Sb half-Heusler thermoelectric materials Nb1-xTixFe1.02Sb half-Heusler thermoelectric materials were synthesized trough arc melting and subsequent spark plasma sintering (SPS). Doping effect of Ti at Nb-site results in high power factor due to the optimization of hole carrier concentration. Further, the lattice thermal conductivity reduced as the Ti content increased, which mainly resulted from point defects and mass fluctuation by Ti doping as well as coherent nano-scale second phase, Ti-rich and Fe-deficient Ti1.18Fe0.57Sb. For the sample of Nb0.6Ti0.4Fe1.02Sb, a minimum lattice thermal conductivity of -2.08 W/mK was obtained. This is attributed to the enhanced phonon scattering at the alternating white and dark lamellar interphase boundaries of (Nb0.6,Ti0.4)FeSb half-Heusler and Nb-doped Ti1.18Fe0.57Sb. A maximum thermoelectric figure of merit, ZT, of -0.81 was obtained at 973 K, which is comparable with values previously reported for this system. Jeong, Hyerin; Kihoi, Samuel Kimani; Kahiu, Joseph Ngugi; Kim, Hyunji; Ryu, Juhee; Lee, Kyu Hyoung; Yi, Seonghoon; Lee, Ho Seong Kyungpook Natl Univ, Sch Mat Sci & Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Hydrogen & Renewable Energy, 80 Daehak Ro, Daegu 41566, South Korea; Yonsei Univ, Dept Mat Sci & Engn, Seoul 03722, South Korea Kihoi, Samuel Kimani/IUM-8515-2023; Yi, Seonghoon/HGC-6912-2022 57208400603; 57208396874; 57222096169; 57208408040; 57221836336; 35205856800; 14008383000; 55706810400 hs.lee@knu.ac.kr; JOURNAL OF THE EUROPEAN CERAMIC SOCIETY J EUR CERAM SOC 0955-2219 1873-619X 41 7 SCIE MATERIALS SCIENCE, CERAMICS 2021 6.364 5.2 0.75 2025-07-30 14 14 Thermoelectric; NbFeSb; Thermal conductivity; Defected structures; TEM PERFORMANCE; COMPOUND Defected structures; NbFeSb; TEM; Thermal conductivity; Thermoelectric Antimony compounds; Carrier concentration; Crystal lattices; Iron compounds; Nanotechnology; Niobium compounds; Point defects; Spark plasma sintering; Thermal conductivity; Thermoelectric equipment; Thermoelectricity; Titanium; Doping effects; High power factor; Interphase boundaries; Lattice thermal conductivity; Low thermal conductivity; Second phase; Thermo-Electric materials; Thermoelectric figure of merit; Titanium compounds English 2021 2021-07 10.1016/j.jeurceramsoc.2021.02.028 바로가기 바로가기 바로가기 바로가기
Article Physicochemical properties and digestion mechanism of starch-linoleic acid complex induced by multi-frequency power ultrasound The effects of multi-frequencies (mono: 20 kHz, 40 kHz, 60 kHz; dual: 20/40 kHz, 40/60 kHz, 20/60 kHz, and tri: 20/40/60 kHz) on physicochemical properties and in vitro digestibility of arrowhead starch-linoleic acid (AS-LA) complexes were evaluated. The complexing index and FTIR analyses showed that sonication treatment might be helpful in the formation of AS-LA complexes in an ultrasound frequency-dependent manner. The SEM micrographs revealed that the various ultrasonication frequencies caused dense network structure in AS-LA complexes. The XRD showed a V-type crystalline structure with increased crystallinity. Compared with arrowhead starch, a decrease in rapidly digestible starch , and an increase in resistant starch contents of AS-LA under various ultrasound frequencies was due to arrowhead starch and linoleic acid molecular interactions, which inhibited the further binding abilities. As a non-thermal technology, ultrasound could be effectively employed to prepare starch-lipid complexes with significant potential in functional foods and drug delivery systems. Raza, Husnain; Ameer, Kashif; Ren, Xiaofeng; Liang, Qiufang; Chen, Xinxiang; Chen, Huanxin; Ma, Haile Jiangsu Univ, Sch Food & Biol Engn, 301 Xuefu Rd, Zhenjiang 212013, Jiangsu, Peoples R China; Jiangsu Univ, Inst Food Phys Proc, 301 Xuefu Rd, Zhenjiang 212013, Jiangsu, Peoples R China; Chonnam Natl Univ, Dept Integrat Food Biosci & Biotechnol, Gwangju 61186, South Korea; Univ Lahore, Fac Allied Hlth Sci, Univ Inst Diet & Nutr Sci, Lahore 54000, Pakistan; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Univ Sargodha, Inst Food Sci & Nutr, Sargodha 40100, Pakistan ; Ameer, Kashif/H-5449-2019; RAZA, HUSNAIN/L-2912-2019; Raza, HUSNAIN/L-2912-2019; Ma, Haile/JPA-4500-2023; Chen, Xinxiang/MVU-4516-2025 57021224300; 57190066397; 38862692800; 55919395300; 57205079236; 57224830746; 9335378300 renxiaofeng@ujs.edu.cn;lqf@ujs.edu.cn; FOOD CHEMISTRY FOOD CHEM 0308-8146 1873-7072 364 SCIE CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS 2021 9.231 5.2 3.98 2025-07-30 62 72 Ultrasound; Starch-lipid complex; Arrowhead tuber; Physicochemical properties; Digestion; Microstructure IN-VITRO DIGESTIBILITY; PRESSURE Arrowhead tuber; Digestion; Microstructure; Physicochemical properties; Starch-lipid complex; Ultrasound Digestion; Linoleic Acid; Sonication; Starch; Complex networks; Crystallinity; Drug delivery; Linoleic acid; Starch; Ultrasonics; distilled water; linoleic acid; resistant starch; starch; Arrowhead tuber; Digestion; In-vitro; Linoleic; Multi frequency; Physicochemical property; Power ultrasound; Starch-lipid complexes; Ultrasound frequency; Vitro digestibilities; arrowhead; Article; binding affinity; clinical evaluation; comparative study; complex formation; controlled study; crystal structure; digestion; drug delivery system; Fourier transform infrared spectroscopy; frequency analysis; functional food; in vitro study; microphotography; microwave radiation; molecular interaction; nonhuman; physical chemistry; scanning electron microscopy; structure analysis; ultrasound; ultraviolet spectrophotometry; water solubility; digestion; ultrasound; Microstructure English 2021 2021-12-01 10.1016/j.foodchem.2021.130392 바로가기 바로가기 바로가기 바로가기
Article Poly(acrylic acid) Hydrogel Microspheres for a Metal-Ion Sensor Monodispersed cross-linked poly(acrylic acid) (PAA) droplets (PAA X-droplets), prepared using the microfluidic method with in situ ultraviolet curing, were used as small spherical sensors to simultaneously detect both Ca2+ and Mg2+ in human saliva and serum. The PAA X-droplet treated with KOH (PAA(KOH) X-droplet) was used as a reference droplet because of its highly swollen state. The PAA(KOH) X-droplets shrunk in response to the presence of divalent metal ions (Ms) by forming a bridged structure of COO-M-OOC. The sizes of the PAA(KOH) X-droplets were precisely and dynamically monitored in the poly(dimethylsiloxane) (PDMS) channel with passing time when the aqueous metal-ion solutions were flowing at a controlled flow rate. The sizes of the PAA(KOH) X-droplets continuously decreased to the saturated constant size. The saturated size of the PAA(KOH) X-droplet did not change; however, the speed of size reduction increased with an increase in the concentration of the divalent metal ion. The saturated size was studied using the saturated diameter ratio (Rsat-dia) with respect to the initial diameter of the PAA(KOH) X-droplet before the metal-ion treatment, and the speed of the size reduction was investigated using the inverse time to reach half the saturated diameter reduction (T-1/2(-1)). Ca2+ and Mg2+ exhibited Rsat-dia values of 75.9 and 83.6%, respectively, when the flow rate was 5 mu L min(-1), regardless of the metal concentration. The T(1/2)(-1)s for the Ca2+ and Mg2+ linearly increased with an increase in their concentrations. The Rsat-dia of the aqueous Ca2+/Mg2+ mixture solution had a linear relationship with phi [= C-Ca/(C-Ca + C-Mg), where C-Ca and C-Mg are the molar concentrations of Ca2+ and Mg2+, respectively]. The T-1/2(-1) of the aqueous Ca2+, Mg2+ mixture solution was calculated by adding the individual T(1/2)(-1)s of pure aqueous Ca2+ and Mg2+ solutions. Using the Rsat-dia and T-1/2(-1) of the Ca2+/Mg2+ mixture aqueous solution, the individual C-Ca and C-Mg in the mixture solution were successfully calculated. This method was applied to the human saliva and serum in which the major metal ions are Ca2+ and Mg2+, and other metal ions existed in undetectable amounts by the PAA(KOH) X-droplets. This method is simple, cost-effective, and highly accurate and solves the hurdles of separating the interference effect of a Mg2+ ion when a Ca2+ ion is measured in biofluids. Tan, Hao; Park, Soo-Young Kyungpook Natl Univ, Sch Appl Chem Engn, Polymer Nano Mat Lab, Daegu 41566, South Korea park, soo-young/N-3170-2017 56895457900; 57194041850 psy@knu.ac.kr; ACS SENSORS ACS SENSORS 2379-3694 6 3 SCIE CHEMISTRY, ANALYTICAL;CHEMISTRY, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY 2021 9.618 5.2 1.1 2025-07-30 18 18 calcium; biosensor; hydrogel; microfluidics; poly(acrylic acid); magnesium biosensor; calcium; hydrogel; magnesium; microfluidics; poly(acrylic acid) Acrylic Resins; Humans; Hydrogels; Ions; Microspheres; Body fluids; Carboxylic acids; Cost effectiveness; Drops; Inverse problems; Magnesium compounds; Metal ions; Metals; Microfluidics; Mixtures; Molar concentration; Potassium hydroxide; Size determination; acrylic acid resin; carbopol 940; ion; microsphere; Bridged structures; Interference effects; Linear relationships; Metal concentrations; Metal ion solutions; Microfluidic method; Poly(acrylic acid) hydrogel; Polydimethylsiloxane PDMS; human; hydrogel; Calcium compounds English 2021 2021-03-26 10.1021/acssensors.0c02269 바로가기 바로가기 바로가기 바로가기
Article Secrecy Enhancing of SSK Systems for IoT Applications in Smart Cities The secure exchange of messages between different communication devices is a major issue of Internet-of-Things (IoT) applications in future smart cities. Current security mechanisms focus on multiple antennas technology, such as spatial modulation (SM), but in space shift keying (SSK), there is still a space to explore. In this article, we propose a secrecy-enhancing SSK scheme for IoT applications by applying security technologies in the physical layer wherein the number of transmit antennas is arbitrary rather than the value of power of two. In this scheme, the security performance of the communication system is improved by using two technologies, namely, artificial noise (AN) and antenna selection. We assume that the application scenario of the SSK system is under the classic eavesdropping model. First, we design ANs according to the channel state information (CSI) to interrupt the eavesdropper and benefit the legitimate receiver via the appropriate cancellation technology. Second, the antenna selection method is designed based on the signal to leakage noise ratio (SLNR) to further boost the secrecy performance by expanding the mutual information difference between the main channel and the eavesdropping channel. Results from our simulations indicate that by the use of the proposed scheme, significant secrecy enhancing can be achieved in terms of bit error ratio (BER) and secrecy rate (SR) when compared with existing schemes. This achieved secrecy enhancing can benefit the suitable IoT communication applications in the smart city environment to avoid the leakage of data transmission. Huang, Zhentao; Peng, Yuyang; Li, Jun; Tong, Fei; Zhu, Konglin; Peng, Limei Macau Univ Sci & Technol, Fac Informat Technol, Macau, Peoples R China; Guangzhou Univ, Sch Elect & Commun Engn, Guangzhou 510006, Peoples R China; Southeast Univ, Sch Cyber Sci & Engn, Nanjing 210096, Peoples R China; Southeast Univ, Purple Mt Labs, Nanjing 210096, Peoples R China; Beijing Univ Posts & Telecommun, Sch Artificial Intelligence, Beijing 100876, Peoples R China; Purple Mt Labs, Nanjing, Peoples R China; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu 41566, South Korea peng, yuyang/IQT-0720-2023; Huang, Zhentao/HNC-3467-2023 57219575329; 56501010700; 36959620500; 36184842000; 36023079700; 7201574271 624165883@qq.com;yypeng@must.edu.mo;lijun52018@gzhu.edu.cn;ftong@seu.edu.cn;klzhu@bupt.edu.cn;auroraplm@knu.ac.kr; IEEE INTERNET OF THINGS JOURNAL IEEE INTERNET THINGS 2327-4662 8 8 SCIE COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS 2021 10.238 5.2 0.82 2025-07-30 11 14 Internet of Things (IoT); secrecy enhancing; smart cities; space shift keying (SSK) WIRELESS SENSOR NETWORKS; SPATIAL MODULATION; MIMO Internet of Things (IoT); secrecy enhancing; smart cities; space shift keying (SSK) Antennas; Bit error rate; Channel state information; Security systems; Smart city; Antenna selection; Application scenario; Bit error ratio (BER); Communication application; IOT applications; Mutual informations; Security performance; Security technology; Internet of things English 2021 2021-04-15 10.1109/jiot.2021.3050331 바로가기 바로가기 바로가기 바로가기
Article Structural characterization, functional properties and antioxidant activities of polysaccharide extract obtained from okra leaves (Abelmoschus esculentus) Polysaccharides have been isolated from okra pods (Abelmoschus esculentus), with little focus on the leaves. This study characterized a water-soluble polysaccharide isolated from okra leaves (OLP), and investigated its functional properties, for their potential applications. FT-IR and NMR spectroscopy were used to describe structural characteristics and the influence on functional properties was examined. The result revealed OLP as a low-molecular-weight polysaccharide (26.9 x 10(3) g/mol(-1)) consisting of galactose (similar to 54 mol%), galacturonic acid (similar to 29 mol%), rhamnose (similar to 9mol%) and arabinose (similar to 5mol%) as the primary sugars, and rhamnogalacturonan-I as the predominant structural unit. OLP was found to be an extensively-branched, highly acetylated, and unmethylated polysaccharide. OLP exhibited non-Newtonian flow behavior and showed comparable or superior functional properties such as thermal stability and emulsifying capacity, and higher antioxidant capacity than polysaccharide previously obtained from okra pods. This study presents a means of utilizing okra leaves as a new polysaccharide source, with potential applications in food-related industries. Olawuyi, Ibukunoluwa Fola; Lee, Won Young Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea Lee, Wonyoung/AAL-2780-2021; Olawuyi, Ibukunoluwa/H-1232-2018 57204471854; 57195940408 ifolawuyi@knu.ac.kr;wonyoung@knu.ac.kr; FOOD CHEMISTRY FOOD CHEM 0308-8146 1873-7072 354 SCIE CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS 2021 9.231 5.2 6.04 2025-07-30 106 114 Okra leaf; Polysaccharides; Extraction; Structural characterization; Emulsion stability EMULSIFYING PROPERTIES; PURIFICATION; MUCILAGE; PECTINS; GUM Emulsion stability; Extraction; Okra leaf; Polysaccharides; Structural characterization Abelmoschus; Antioxidants; Magnetic Resonance Spectroscopy; Plant Leaves; Polysaccharides; Rheology; Spectroscopy, Fourier Transform Infrared; Temperature; Antioxidants; Extraction; Nuclear magnetic resonance spectroscopy; Polysaccharides; Abelmoschus esculentus extract; antioxidant; arabinose; galactose; galacturonic acid; glucose; plant extract; polysaccharide; rhamnose; unclassified drug; antioxidant; polysaccharide; Abelmoschus esculentus; Antioxidant activities; Emulsion stability; Functional properties; IR and NMR spectroscopy; Low molecular weight; Okra leaf; Structural characteristics; Structural characterization; Water-soluble polysaccharides; antioxidant activity; Article; bulk density; controlled study; drug structure; emulsion; Fourier transform infrared spectroscopy; heteronuclear single quantum coherence; IC50; nonhuman; nuclear magnetic resonance spectroscopy; okra; physical chemistry; plant leaf; protein content; proton nuclear magnetic resonance; shear rate; thermostability; viscosity; Abelmoschus; chemistry; flow kinetics; infrared spectroscopy; metabolism; plant leaf; temperature; Emulsification English 2021 2021-08-30 10.1016/j.foodchem.2021.129437 바로가기 바로가기 바로가기 바로가기
Article Generation of multi-dimensional defect structures for synergetic engineering of hole and phonon transport: enhanced thermoelectric performance in Sb and Cu co-doped GeTe A facile compositional tuning by Sb and Cu addition is performed to generate engineered defects in GeTe alloys with ultra-low thermal conductivity. Substitution of Sb and Cu at the Ge-site enhances the power factor due to the optimization of carrier concentration while maintaining the convergence of the valence bands. Furthermore, complex multi-dimensional defect structures including 0D (0-dimensional) substituted Sb-Ge and Cu-Ge, 2D twin and inversion boundaries, 3D herringbone structures, 3D embedded nanostructures, and 3D Cu-rich coherent precipitates are generated, which significantly reduce the lattice thermal conductivity benefitting from a collective phonon scattering. Due to this simultaneous manipulation of electronic and thermal transport properties, a maximum thermoelectric figure of merit (zT) of 1.4 was obtained at 723 K. Kim, Hyunho; Park, Chul Oh; Jeong, Hyerin; Kihoi, Samuel Kimani; Yi, Seonghoon; Kim, Hyun-Sik; Lee, Kyu Hyoung; Lee, Ho Seong Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Yonsei Univ, Dept Mat Sci & Engn, Seoul 03722, South Korea; Hongik Univ, Dept Mat Sci & Engn, Seoul 04066, South Korea Yi, Seonghoon/HGC-6912-2022; Kim, Hyunho/ABG-6038-2021; Kihoi, Samuel Kimani/IUM-8515-2023; Kim, Sung/A-4747-2013 58204142300; 57224363615; 57208400603; 57208396874; 14008383000; 56526077500; 35205856800; 55706810400 khlee2018@yonsei.ac.kr;hs.lee@knu.ac.kr; INORGANIC CHEMISTRY FRONTIERS INORG CHEM FRONT 2052-1553 8 11 SCIE CHEMISTRY, INORGANIC & NUCLEAR 2021 7.779 5.4 1.01 2025-07-30 12 12 Carrier concentration; Coherent scattering; Copper; Defect structures; Defects; Germanium compounds; Phonons; Thermal conductivity of solids; Thermoelectricity; Coherent precipitates; Compositional tuning; Electronic and thermal transports; Inversion boundaries; Lattice thermal conductivity; Low thermal conductivity; Thermoelectric figure of merit; Thermoelectric performance; Antimony English 2021 2021-06-07 10.1039/d1qi00100k 바로가기 바로가기 바로가기 바로가기
Article Lung virome: New potential biomarkers for asthma severity and exacerbation Background: Although some respiratory virus infections are known to contribute to the development and exacerbation of asthma, commensal viromes in airway have not been extensively studied due to technical challenges. Objectives: This study investigated the characteristics of the virome in asthmatic airways. Methods: Both the bacteriome and virome profiles in sputum from 12 healthy individuals, 15 patients with nonsevere asthma, and 15 patients with severe asthma were analyzed and assessed for the association with clinical characteristics such as severity, exacerbation, Asthma Control Test (ACT), and lung function. Results: While analysis of the 16S ribosomal RNA bacteriome in the airway showed no differences, clear contrasts in the diversity and composition of airway viromes were observed between healthy controls and patients with asthma. Herpesviruses were the most abundant type of virus in the asthma group (44.6 +/- 4.6%), mainly with cytomegalovirus (CMV) and EBV accounting for 24.5 +/- 3.3% and 16.9 +/- 3.5%, respectively, in contrast to those in the healthy controls (5.4 +/- 2.5% and 7.1 +/- 3.0%, respectively). CMV and EBV were more abundant in patients with asthma who experienced exacerbation, and their abundance showed correlation with more severe asthma, lower ACT score, and lower lung function. On the contrary, bacteriophage that is abundant in healthy controls was severely reduced in patients with asthma in the order of nonsevere and severe asthma and presented significant positive correlation with ACT and FEV1/forced vital capacity. Conclusions: Lung viromes, especially, CMV, EBV, and bacteriophage may be potential biomarkers of asthma severity and exacerbation. Choi, Sungmi; Sohn, Kyoung-Hee; Jung, Jae-Woo; Kang, Min-Gyu; Yang, Min-Suk; Kim, Sujeong; Choi, Jeong-Hee; Cho, Sang-Heon; Kang, Hye-Ryun; Yi, Hana Korea Univ, Inst Biomat, Seoul, South Korea; Korea Univ, Interdisciplinary Program Precis Publ Hlth, Seoul, South Korea; Korea Univ, Sch Biosyst & Biomed Sci, 145 Anam Ro, Seoul 02841, South Korea; Seoul Natl Univ, Coll Med, Med Res Ctr, Inst Allergy & Clin Immunol, Seoul, South Korea; Kyung Hee Univ Hosp, Dept Internal Med, Seoul, South Korea; Chung Ang Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Dept Internal Med, Coll Med, Cheongju, South Korea; Seoul Natl Univ, Dept Internal Med, Seoul Metropolitan Govt, Boramae Med Ctr, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Hallym Univ, Dongtan Sacred Heart Hosp, Dept Pulmonol & Allergy, Hwaseong, South Korea; Hallym Univ, Coll Med, Allergy & Clin Immunol Res Ctr, Chunchon, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea Sohn, Kyoung-Hee/HNJ-2671-2023; Kim, Ju-Hyoung/N-1450-2019; Jung, Jae-Woo/L-9451-2019 56856237700; 55901812200; 57189648165; 55908899100; 7404927140; 36666447400; 7501395695; 56582804700; 7404070922; 7202720196 helenmed@snu.ac.kr;hanayi@korea.ac.kr; JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY J ALLERGY CLIN IMMUN 0091-6749 1097-6825 148 4 SCIE ALLERGY;IMMUNOLOGY 2021 14.29 5.4 2.29 2025-07-30 39 40 Asthma; herpesvirus; CMV; EBV; virome; metagenomics; microbiome RISK-FACTORS; AGE Asthma; CMV; EBV; herpesvirus; metagenomics; microbiome; virome Adult; Aged; Asthma; Biomarkers; Disease Progression; Female; Herpesviridae; Humans; Lung; Male; Middle Aged; Respiratory Function Tests; RNA, Ribosomal, 16S; Severity of Illness Index; Sputum; Virome; 25 hydroxyvitamin D; biological marker; corticosteroid; dithiothreitol; immunoglobulin E; methacholine; RNA 16S; transcription factor RUNX2; biological marker; Actinomyces; adult; allergic rhinitis; Article; asthma; Asthma Control Questionnaire; Asthma Control Test; bacterial microbiome; bacteriophage; clinical article; commensal; controlled study; coughing; Cytomegalovirus; disease exacerbation; disease severity; dyspnea; eosinophilia; Epstein Barr virus; Escherichia; ex-smoker; female; forced expiratory volume; forced vital capacity; Fusobacterium; gene mapping; Haemophilus; Herpesviridae; human; Klebsiella; Leptotrichia; lung function; lung function test; lung microbiota; male; Neisseria; non-smoker; nonhuman; Porphyromonas; Prevotella; provocation test; severe asthma; sputum; Streptococcus; Streptococcus phage; Veillonella; virome; virus genome; wheezing; aged; asthma; disease exacerbation; genetics; isolation and purification; lung; middle aged; pathophysiology; severity of illness index; virology English 2021 2021-10 10.1016/j.jaci.2021.03.017 바로가기 바로가기 바로가기 바로가기
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