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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI ⓘ FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
○ ○ Article ⓘ Output Stabilizing Control of Complex Biological Networks Based on Boolean Algebra Analysis ⓘ Output stabilizing control of biological systems is of utmost importance in systems biology since key phenotypes of biological networks are often encoded by a small subset of their phenotypic marker nodes. This study addresses the challenge of output stabilizing control for complex biological systems modeled by Boolean networks (BNs). The objective is to identify a set of constant control inputs capable of driving the BN toward a desirable long-term behavior with respect to specified output nodes. Leveraging the algebraic properties of Boolean logic, we develop a novel control algorithm that reformulates the output stabilizing control problem into a simple graph theoretic problem involving auxiliary BNs, the scale of which significantly decreases compared to the original BN. The proposed method ensures superiority over previous results in terms of both the number of control inputs and computational loads, since it searches for the solution within the reduced BNs while retaining essential structures needed for output stabilization. The efficacy of the proposed control scheme is demonstrated through extensive numerical experiments with complex random BNs and real biological networks. To support the reproducible research initiative, detailed results of numerical experiments are provided in the supplementary material, and all the implementation codes are made accessible at https://github.com/choonlog/OutputStabilization. ⓘ Yang, Jung-Min; Lee, Chun-Kyung; Cho, Kwang-Hyun ⓘ Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Korea Adv Inst Sci & Technol KAIST, Dept Bio & Brain Engn, Daejeon 34141, South Korea ⓘ ⓘ 57208450551; 57202995708; 35263583400 ⓘ jmyang@ee.knu.ac.kr; chunkyung@kaist.ac.kr; ckh@kaist.ac.kr; ⓘ IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS ⓘ IEEE T NEUR NET LEAR ⓘ 2162-237X 2162-2388 36 5 SCIE COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE;COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, ELECTRICAL & ELECTRONIC ⓘ 2024 8.9 4.2 0.31 2025-05-07 ⓘ 2 2 Boolean algebra analysis; Boolean networks (BNs); complex networks; network reduction; output stabilization; systems biology; Boolean algebra analysis; Boolean networks (BNs); complex networks; network reduction; output stabilization; systems biology ⓘ EDGE DYNAMICS; TARGET CONTROL; TRACKING; SYSTEMS ⓘ Boolean algebra analysis; Boolean networks (BNs); complex networks; network reduction; output stabilization; systems biology ⓘ Biological systems; Boolean algebra; Control systems; Graph theory; Multi agent systems; Stabilization; Biological networks; Boolean algebra analyse; Boolean network; Boolean Networks; Network reduction; Output stabilization; Regulation; Stabilizing control; Systems biology; algorithm; article; clinical article; controlled study; phenotype; systems biology; Complex networks ⓘ English 2025 2025-05 10.1109/tnnls.2024.3430906 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Retraction ⓘ RETRACTION: A study on the role of surface functional groups of metakaolin in the removal of methylene blue: Characterization, kinetics, modeling and RSM optimization ⓘ ⓘ Karuppaiyan, Janani; Jeyalakshmi, R.; Kiruthika, S.; Wadaan, Mohammad Ahmad; Khan, Muhammad Farooq; Kim, Woog ⓘ SRM Inst Sci & Technol, Coll Engn & Technol, Dept Chem, Kattankulathur 603203, India; SRM Inst Sci & Technol, Coll Engn & Technol, Dept Chem Engn, Kattankulathur 603203, India; King Saud Univ, Coll Sci, Dept Zool, Riyadh 11451, Saudi Arabia; Kyungpook Natl Univ, Dept Environm Engn, Sangju, South Korea ⓘ Wadaan, Mohammad/JLK-8900-2023; Khan, Muhammad Farooq S/AAA-8438-2022 ⓘ 58038459500; 55315686000; 56430997500; 15045991900; 59217155900; 58155870800 ⓘ ⓘ ENVIRONMENTAL RESEARCH ⓘ ENVIRON RES ⓘ 0013-9351 1096-0953 267 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2024 7.7 4.2 0 2025-05-07 ⓘ 0 0 ⓘ ⓘ ⓘ controlled study; erratum; human ⓘ English 2025 2025-02-15 10.1016/j.envres.2025.120850 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Retraction ⓘ RETRACTION: Bioremediations analysis using multifactorial porous materials derived from tea residue ⓘ ⓘ Kaliaperumal, Vimal; Subramaniyan, Vijayakumar; Renganathan, Sangeetha; Mohandoss, Nilavukkarasi; Hatamleh, Ashraf Atef; Alnafisi, Bassam Khalid; Kim, Woong; Subramaniyan, Prathipkumar ⓘ Bharathidasan Univ, AVVM Sri Pushpam Coll, PG & Res Dept Bot, Thanjavur, India; Bharathidasan Univ, AVVM Sri Pushpam Coll, PG & Res Dept Math, Thanjavur, India; King Saud Univ, Coll Sci, Dept Bot & Microbiol, POB 2455, Riyadh 11451, Saudi Arabia; Natl Inst Technol Trichy, Tiruchirappalli 620015, Tamil Nadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea ⓘ Hatamleh, Ashraf/GQZ-8861-2022 ⓘ 57948633300; 59524058700; 57949486900; 57948762300; 55881612200; 57936260700; 55581636400; 57949372000 ⓘ ⓘ ENVIRONMENTAL RESEARCH ⓘ ENVIRON RES ⓘ 0013-9351 1096-0953 267 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2024 7.7 4.2 0 2025-05-07 ⓘ 0 0 ⓘ ⓘ ⓘ erratum ⓘ English 2025 2025-02-15 10.1016/j.envres.2025.120849 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Retraction ⓘ RETRACTION: Enhanced membraneless fuel cells by electrooxidation of ethylene glycol with a nanostructured cobalt metal catalyst ⓘ ⓘ Aarimuthu, Gayathri; Sathiasivan, Kiruthika; Varadharajan, Selvarani; Balakrishnan, Muthukumaran; Albeshr, Mohammed F.; Alrefaei, Abdulwahed Fahad; Kim, Woong ⓘ Univ Madras, Dept Chem, Presidency Coll Autonomous, Chennai 600005, India; SRM Inst Sci & Technol, Coll Engn & Technol, Dept Chem Engn, Chennai 603203, India; St Josephs Inst Technol, Dept Chem, Old Mamallapuram Rd, Chennai 600119, India; King Saud Univ, Dept Zool, Coll Sci, POB 2455, Riyadh 11451, Saudi Arabia; Kyungpook Natl Univ, Dept Environm Engn, Daegu, South Korea ⓘ Farah, Mohammad/F-7972-2010; S, KIRUTHIKA/ABE-8631-2021 ⓘ 58482877000; 59454904500; 58483049100; 6603252722; 57202952715; 57207669967; 55581636400 ⓘ ⓘ ENVIRONMENTAL RESEARCH ⓘ ENVIRON RES ⓘ 0013-9351 1096-0953 280 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2024 7.7 4.2 0 2025-06-11 ⓘ 0 0 ⓘ ⓘ ⓘ erratum; human; controlled study; drug toxicity ⓘ English 2025 2025-09-01 10.1016/j.envres.2025.121962 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Retraction ⓘ RETRACTION: Enhanced photocatalytic efficiencies in a bifunctional ZnO/PVA nanocomposites derived from Capparis zeylanica L. ⓘ ⓘ Subramaniyan, Prathipkumar; Subramaniyan, Vijayakumar; Renganathan, Sangeetha; Elavarasan, Vidhya; Al-Ansari, Mysoon M.; Aldawsari, Majdoleen; Kala, Praseetha Prabhakaran; Kim, Woong ⓘ SRM Inst Sci & Technol, Nanotechnol Res Ctr, Chennai, India; Bharathidasan Univ, AVVM Sri Pushpam Coll Autonomous, PG & Res Dept Bot, Tiruchirappalli 613503, India; Bharathidasan Univ, AVVM Sri Pushpam Coll Autonomous, Dept Math, Tiruchirappalli 613503, India; King Saud Univ, Coll Sci, Dept Bot & Microbiol, Riyadh 11451, Saudi Arabia; Noorul Islam Ctr Higher Educ, Dept Nanotechnol, Thuckalay, Tamilnadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu, South Korea ⓘ ⓘ 57949372000; 59524058700; 57949486900; 57998183200; 55266071800; 58088505100; 59525312100; 55581636400 ⓘ ⓘ ENVIRONMENTAL RESEARCH ⓘ ENVIRON RES ⓘ 0013-9351 1096-0953 267 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2024 7.7 4.2 0 2025-05-07 ⓘ 0 0 ⓘ ⓘ ⓘ drug therapy; erratum; human ⓘ English 2025 2025-02-15 10.1016/j.envres.2025.120852 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Retraction ⓘ RETRACTION: Intimately coupled gC3N4 photocatalysis and mixed culture biofilm enhanced detoxification of sulfamethoxazole: Elucidating degradation mechanism and toxicity assessment ⓘ ⓘ Sathishkumar, Kuppusamy; Kannan, Velu Rajesh; Alsalhi, Mohamad S.; Rajasekar, Aruliah; Devanesan, Sandhanasamy; Narenkumar, Jayaraman; Kim, Woong; Liu, Xinghui ⓘ Yanan Univ, Sch Phys & Elect Informat, Yanan 716000, Peoples R China; Bharathidasan Univ, Dept Microbiol, Rhizosphere Biol Lab, Tiruchirappalli 620024, Tamil Nadu, India; King Saud Univ, Coll Sci, Dept Phys & Astron, Riyadh 11451, Saudi Arabia; Thiruvalluvar Univ, Dept Biotechnol, Environm Mol Microbiol Res Lab, Vellore 632115, Tamil Nadu, India; Bharath Inst Higher Educ & Res, Ctr Mat Engn & Regenerat Med, Chennai 600073, Tamil Nadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Sungkyunkwan Univ SKKU, Dept Chem, 2066 Seoburo, Suwon 16419, South Korea ⓘ alsalhi, mohamad/M-5013-2019; Devanesan, Dr. Sandhanasamy/ABH-3378-2021; Jayaraman, Narenkumar/JGD-7456-2023; Aruliah, Rajasekar/E-4568-2015 ⓘ 57192713219; 59311557000; 10440259800; 55928874800; 55279721800; 57194229197; 55581636400; 57206739900 ⓘ ⓘ ENVIRONMENTAL RESEARCH ⓘ ENVIRON RES ⓘ 0013-9351 1096-0953 275 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2024 7.7 4.2 0 2025-05-07 ⓘ 0 0 ⓘ ⓘ ⓘ sulfamethoxazole; controlled study; erratum; human; article; biofilm; degradation; detoxification; drug toxicity; mixed cell culture; photocatalysis; retraction notice ⓘ English 2025 2025-06-15 10.1016/j.envres.2025.121124 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Sampled-Data State Estimation for LSTM ⓘ This article first introduces a sampled-data state estimator design method for continuous-time long short-term memory (LSTM) neural networks with irregularly sampled output. To this end, the structure of the LSTM is addressed to obtain its dynamic equation. As a result, the LSTM neural network is modeled as a continuous-time linear parameter-varying system that is dependent on the gate units. For this system, the sampled-data Luenberger- and Arcak-type state estimator design methods are presented in terms of linear matrix inequalities (LMIs) by using the properties of the gate units. Lastly, the proposed method not only provides a numerical example for analyzing absolute stability but also demonstrates it in practice by applying a pre-trained behavior generation model of a robot manipulator. ⓘ Jin, Yongsik; Lee, S. M. ⓘ Elect & Telecommun Res Inst, Robot & Mobil Res Sect, Daegu 42994, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Cyber Phys Syst & Control Lab, Daegu 41566, South Korea ⓘ Jin, Yongsik/AAH-6959-2021; Lee, Sangmoon/C-4502-2018 ⓘ 57020309300; 59510733500 ⓘ yongsik@etri.re.kr; moony@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS ⓘ IEEE T NEUR NET LEAR ⓘ 2162-237X 2162-2388 36 2 SCIE COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE;COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, ELECTRICAL & ELECTRONIC ⓘ 2024 8.9 4.2 5.9 2025-05-07 ⓘ 2 2 Biological neural networks; Neural networks; State estimation; Recurrent neural networks; Logic gates; Design methodology; Mathematical models; Linear matrix inequalities (LMIs); long short-term memory (LSTM); neural networks; sampled-data system; state estimation ⓘ NEURAL-NETWORKS; STABILITY ANALYSIS; IDENTIFICATION; OBSERVER; SYSTEMS ⓘ Linear matrix inequalities (LMIs); long short-term memory (LSTM); neural networks; sampled-data system; state estimation ⓘ Continuous time systems; Linear matrix inequalities; Linear systems; Manipulators; Robot applications; Robustness (control systems); Sampled data control systems; State estimation; Biological neural networks; Data state; Design Methodology; Linear matrix in equalities; Linear matrix inequality; Long short-term memory; Neural-networks; Sampled data; Sampled data systems; article; long short term memory network; nerve cell network; pharmaceutics; Numerical methods ⓘ English 2025 2025-02 10.1109/tnnls.2024.3359211 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Versatile platform of 3D/2D/1D:ZnFe2O4/NiAl-LDH/MWCNTs nanocomposite for photocatalytic purification of dinoseb and electrocatalytic O2 evolution reaction ⓘ Integrating photocatalysis with electrocatalysis may represent a synergistic approach to address environmental and energy challenges. In this context, we explored synthesizing a series of nanocomposite materials using a solid-state approach involving simple grinding and subsequent thermal treatment for the photocatalytic purification of dinoseb and electrocatalytic oxygen evolution (OER). Interestingly, among the series of synthesized materials, 40 wt percentage of 3D/2D/1D:ZnFe2O4/NiAl-LDH/MWCNTs ternary nanocomposite (40-NZM) showed highly improved dinoseb detoxification and OER efficiencies compared to those of pure materials. Importantly, approximately 98% detoxification of dinoseb was observed within 75 min of irradiation time under a visible light source. Remarkably, the 40-NZM nanocomposite exhibited the highest rate constant value (k = 4.1 x 10- 2 min- 1) with a favorable R2 (0.98) parameter. Furthermore, 40-NZM showed promising electrocatalytic OER performance, requiring only 217 mV of overpotential to achieve 10 mAcm- 2 of current density with a smaller Tafel slope of 66.6 mVdec- 1. Additionally, long-term stability was tested by recording 2000 cyclic voltammetry (CV) cycles. The results revealed that 40-NZM could maintain its catalytic activity for a longer duration as it required only 227 mV to attain 10 mAcm- 2 even after 2000 CV cycles. Consequently, these outstanding characteristics of 40-NZM nanocomposite underscore the significant potential for catalytic water purification and sustainable energy conversion. ⓘ Lee, Dong-Eun; Husain, Ahmad; Khan, Azam; Danish, Mohtaram; Jo, Wan-Kuen ⓘ Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, 80 Daehak Ro, Daegu 41566, South Korea; Univ Tenaga Nas, Inst Power Engn, Kajang 43000, Selangor, Malaysia; Jai Prakash Univ, Zakia Afaque Islamia Coll Siwan, Dept Chem, Chapra, Bihar, India ⓘ ; Husain, Ahmad/ACG-5055-2022; Jo, Wan/AAO-5329-2020 ⓘ 56605563300; 57215031715; 56978457300; 57216220743; 7103322277 ⓘ dmohtaram@gmail.com; wkjo@knu.ac.kr; ⓘ ENVIRONMENTAL RESEARCH ⓘ ENVIRON RES ⓘ 0013-9351 1096-0953 264 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ⓘ 2024 7.7 4.2 21.56 2025-05-07 ⓘ 8 8 Photocatalysis; Nanocomposite; Dinoseb; Detoxification; Oxygen evolution; Electrocatalysis ⓘ FACILE SYNTHESIS; WATER-OXIDATION; CARBON NANOTUBE; EFFICIENT; DEGRADATION; NANOPARTICLES; HYDROGEN; PERFORMANCE; COMPOSITES; GRAPHENE ⓘ Detoxification; Dinoseb; Electrocatalysis; Nanocomposite; Oxygen evolution; Photocatalysis ⓘ Catalysis; Electrochemical Techniques; Ferric Compounds; Nanocomposites; Nanotubes, Carbon; Oxygen; Photochemical Processes; Air purification; Detoxification; Nanoclay; Photocatalysis; Selenium compounds; Zinc alloys; Zinc sulfide; aluminum; dinoseb; iron oxide; lactate dehydrogenase; multi walled nanotube; nanocomposite; nickel; norfloxacin; zinc; carbon nanotube; ferric ion; oxygen; Dinoseb; Electrocatalytic; Energy; Evolution reactions; MWCNT's; Oxygen evolution; Photo-catalytic; Simple++; Solid state approach; Thermal; alternative energy; chemical reaction; detoxification; electrokinesis; herbicide; nanocomposite; oxygen; photolysis; purification; Article; controlled study; current density; cyclic voltammetry; degradation kinetics; detoxification; ecosystem restoration; electrocatalysis; electron; energy conversion; field emission scanning electron microscopy; grinding; isotherm; light; linear sweep voltammetry; oxidation reduction potential; oxygen evolution reaction; photocatalysis; photodegradation; polarization; purification; rate constant; reference electrode; solid state; substrate concentration; surface area; synthesis; water management; water supply; X ray diffraction; catalysis; chemistry; electrochemical analysis; photochemistry; procedures; Cyclic voltammetry ⓘ English 2025 2025-01-01 10.1016/j.envres.2024.120367 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Managerial pessimism and investment in corporate social responsibility ⓘ This study examines the relationship between managerial pessimism and firms' investment in corporate social responsibility (CSR). We find that managerial pessimism is positively associated with CSR investment. This result is consistent with the argument that pessimistic managers are more likely to increase their CSR investment to benefit from the insurance-like protection provided by a positive CSR reputation. Additionally, pessimistic managers are less likely to decrease CSR investment because such activities serve as a control mechanism to curb excessive risk-taking. Cross-sectional analyses reveal that this positive association is stronger for firms with higher operating uncertainty, litigation risk, and analyst following and "sinful" firms. Under these circumstances, pessimistic managers are more likely to invest in CSR, using it as a risk management tool and shareholder monitoring mechanism. Overall, this study suggests that managerial pessimism is an important factor that affects CSR investments. ⓘ Koo, KwangJoo (KJ); Kim, Jae B. ⓘ Kyungpook Natl Univ, Coll Econ & Business Adm, 80 Daehak Ro, Daegu 41566, South Korea; Coll Business, Dept Accounting, 621 Taylor St, Bethlehem, PA 18015 USA ⓘ Koo, KwangJoo/AAM-6949-2020 ⓘ 57202687309; 57189367818 ⓘ kjkoo@knu.ac.kr; jbk317@lehigh.edu; ⓘ JOURNAL OF BUSINESS RESEARCH ⓘ J BUS RES ⓘ 0148-2963 1873-7978 186 SSCI BUSINESS ⓘ 2024 9.8 4.3 0 2025-05-07 ⓘ 3 3 Managerial Sentiment; Pessimism; Corporate Social Responsibility; Firm Investment ⓘ FINANCIAL PERFORMANCE; SHAREHOLDER WEALTH; TEXTUAL ANALYSIS; FIRM AGE; SENTIMENT; RISK; IMPACT; CEOS; INSURANCE; STYLE ⓘ Corporate Social Responsibility; Firm Investment; Managerial Sentiment; Pessimism ⓘ ⓘ English 2025 2025-01 10.1016/j.jbusres.2024.114953 ⓘ 바로가기 바로가기 바로가기 바로가기
○ Article ⓘ A Natural Current Balancing Interleaved IPOP LLC Converter With Partial Power Processing ⓘ This article proposes a natural current balancing method for the interleaved input-parallel output-parallel (IPOP) LLC converter incorporating the partial power processing (PPP) structure. In the proposed configuration, based on the principle of charge balance, the voltage gain of phases can be automatically equalized in the presence of parameter mismatch. This results in the natural balancing of phase currents without sensors or dedicated controls and is independent of the phase-shift angle. Consequently, interleaving operation with 90° phase shift can be employed to reduce output current ripples significantly. Additionally, the PPP structure allows the output voltage of the proposed converter to be regulated with high performance. A 2-kW prototype is built and tested to validate the benefits of the proposedmethod. © 1982-2012 IEEE. ⓘ Tran, Thien-Dung; Cha, Honnyong; Bui, Van-Dai ⓘ Kyungpook National University, School of Energy Engineering, Daegu, 41566, South Korea; Kyungpook National University, School of Energy Engineering, Daegu, 41566, South Korea; North Carolina State University, FREEDM Systems Center, Raleigh, 27606, NC, United States ⓘ ⓘ 58572374600; 59810211800; 57221961296 ⓘ chahonny@knu.ac.kr; ⓘ IEEE Transactions on Industrial Electronics ⓘ IEEE T IND ELECTRON ⓘ 0278-0046 1557-9948 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION ⓘ 2024 7.2 4.4 0 2025-06-11 ⓘ 0 ⓘ ⓘ Current balancing; input-parallel outputparallel (IPOP) converter; interleaving effect; LLC-DCX; partial power processing (PPP); ripple cancelation ⓘ Current balancing; Input-parallel outputparallel converter; Interleaving effect; Interleavings; LLC-DCX; Output-parallel converters; Partial power; Partial power processing; Power processing; Ripple cancellation ⓘ English Article in press 2025 10.1109/tie.2025.3566748 ⓘ 바로가기 바로가기 바로가기
○ ○ Review ⓘ AbOmpA in Acinetobacter baumannii: exploring virulence mechanisms of outer membrane-integrated and outer membrane vesicle-associated AbOmpA and developing anti-infective agents targeting AbOmpA ⓘ Acinetobacter baumannii is notorious for its antimicrobial resistance and its potential to cause epidemics in hospital settings, which pose a global health threat. Although this microorganism is traditionally considered a low-virulence pathogen, extensive research has been conducted on its virulence and pathogenesis in recent years. Advances in understanding the virulence mechanisms of A. baumannii have prompted a shift in the development of anti-infective agents. The outer membrane protein A (AbOmpA) of A. baumannii is a key virulence factor both in vitro and in vivo. AbOmpA exists in three forms: outer membrane-integrated AbOmpA, outer membrane vesicle (OMV)-associated AbOmpA, and free proteins. Given that outer membrane-integrated AbOmpA has been implicated in the virulence and antimicrobial resistance of A. baumannii, many studies have focused on outer membrane-integrated AbOmpA as a therapeutic target for combating drug-resistant A. baumannii, and have led to the discovery of small molecules, polypeptides, and antimicrobial peptides targeting AbOmpA. However, the pathophysiological role of OMV-associated AbOmpA and its impact on AbOmpA-targeting agents remain unclear. This review summarizes the current knowledge of AbOmpA and critically discusses OMV-associated AbOmpA in relation to virulence and its potential impact on AbOmpA-targeted therapies to provide a better understanding of AbOmpA for the development of novel therapeutics against A. baumannii. ⓘ Oh, Man Hwan; Islam, Md Minarul; Kim, Nayeong; Choi, Chul Hee; Shin, Minsang; Shin, Woo Shik; Lee, Je Chul ⓘ Dankook Univ, Dept Microbiol, Cheonan 31116, South Korea; Dankook Univ, Smart Anim Bio Inst, Cheonan 31116, South Korea; Kyungpook Natl Univ, Dept Microbiol, Sch Med, Daegu 41944, South Korea; Chungnam Natl Univ, Sch Med, Dept Microbiol, Daejeon 35015, South Korea; Kyungpook Natl Univ, Untreatable Infect Dis Inst, Daegu 41944, South Korea; Northeast Ohio Med Univ, Dept Pharmaceut Sci, Rootstown, OH USA ⓘ ⓘ 59919681800; 57402857100; 57211500281; 54379495100; 7401536650; 57203789140; 25930392000 ⓘ yy1091@dankook.ac.kr; mislambcmb@gmail.com; tbc02021@naver.com; choich@cnu.ac.kr; shinms@knu.ac.kr; austinshin7@gmail.com; leejc@knu.ac.kr; ⓘ JOURNAL OF BIOMEDICAL SCIENCE ⓘ J BIOMED SCI ⓘ 1021-7770 1423-0127 32 1 SCIE CELL BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL ⓘ 2024 12.1 4.4 0 2025-06-11 ⓘ 0 0 Acinetobacter baumannii; Outer membrane protein A; Outer membrane vesicle; Virulence factor; Anti-infective agent ⓘ PROTEIN-A; BIOFILM FORMATION; ANTIMICROBIAL RESISTANCE; IMMUNE-RESPONSE; DENDRITIC CELLS; OMPA PROTEIN; LIPOPOLYSACCHARIDE; PLAYS; PATHOGENESIS; CONTRIBUTES ⓘ Acinetobacter baumannii; Anti-infective agent; Outer membrane protein A; Outer membrane vesicle; Virulence factor ⓘ Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Humans; Virulence; Virulence Factors; antiinfective agent; outer membrane protein A; polypeptide; polypeptide antibiotic agent; virulence factor; antiinfective agent; outer membrane protein; Acinetobacter baumannii; antibiotic resistance; drug resistance; human; in vitro study; membrane vesicle; nonhuman; outer membrane; review; Acinetobacter infection; drug effect; drug therapy; genetics; metabolism; microbiology; pathogenicity; virulence ⓘ English 2025 2025-05-27 10.1186/s12929-025-01147-5 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ An Isolated High-Voltage-Gain Resonant Converter Utilizing Voltage Quadrupler With Bidirectional-Switch for Fuel-Cell Applications ⓘ This article proposes a high-voltage-gain resonant converter with zero input current ripple for fuel cell applications. The proposed converter comprises an interleaved current-fed bridge and a voltage quadrupler rectifier with a bidirectional switch on the primary and secondary sides of the transformer, respectively, for achieving high-voltage gain and zero input current ripple. Furthermore, it can achieve an additional increase in voltage gain by adjusting the duty cycle of the bidirectional switch, even with a fixed duty cycle of 0.5, which simultaneously ensures ripple-free input current. So, these structural advantages allow the converter to achieve a much higher voltage gain with the least transformer turns-ratio value than existing step-up converters. The voltage quadrupler also makes the output component's voltage stress half the output voltage. In addition, the resonant operation enables all the switches and diodes to fully attain soft switching over the operating voltage range. Thus, the reverse recovery problem of the diodes and the switching loss for all switches can be eliminated. Its operating principles and theoretical derivations of the converter are discussed in detail. The effectiveness and performance of the proposed converter were verified using a 400-W prototype operating under input voltage ranging from 38 to 48 V inputs and an output voltage of 380 V, achieving a peak efficiency of 96.4%. ⓘ Yea, Jaeseob; Han, Byeongcheol ⓘ Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea ⓘ ; Han, Byeongcheol/W-7608-2019 ⓘ 58572477000; 57188622752 ⓘ yetiger6@knu.ac.kr; hbychol@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS ⓘ IEEE T IND ELECTRON ⓘ 0278-0046 1557-9948 72 1 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION ⓘ 2024 7.2 4.4 2.89 2025-05-07 ⓘ 2 2 Switches; Voltage; Transformers; High-voltage techniques; Capacitors; Inductors; Voltage control; Fuel cell; input current ripple; isolated resonant converter; quadruple rectifier; step-up converter ⓘ DC-DC CONVERTER; CURRENT-RIPPLE; INPUT VOLTAGE; RANGE ⓘ Fuel cell; input current ripple; isolated resonant converter; quadruple rectifier; step-up converter ⓘ Rectifying circuits; Bidirectional switch; Current fed; Fuel cell application; High voltage gain; Input current ripple; Isolated resonant converter; Output voltages; Quadruple rectifier; Resonant converters; Step-up converter ⓘ English 2025 2025-01 10.1109/tie.2024.3413830 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Endothelial RUNX3 controls LSEC dysfunction and angiocrine LRG1 signaling to prevent liver fibrosis ⓘ Background and Aims Liver fibrosis represents a global health burden, given the paucity of approved antifibrotic therapies. Liver sinusoidal endothelial cells (LSECs) play a major gatekeeping role in hepatic homeostasis and liver disease pathophysiology. In early tumorigenesis, runt-related transcription factor 3 (RUNX3) functions as a sentinel; however, its function in liver fibrosis in LSECs remains unclear. This study aimed to investigate the role of RUNX3 as an important regulator of the gatekeeping functions of LSECs and explore novel angiocrine regulators of liver fibrosis. Approach and Results Mice with endothelial Runx3 deficiency develop gradual and spontaneous liver fibrosis secondary to LSEC dysfunction, thereby more prone to liver injury. Mechanistic studies in human immortalized LSECs and mouse primary LSECs revealed that IL-6/JAK/STAT-3 pathway activation was associated with LSEC dysfunction in the absence of RUNX3. Single-cell RNA sequencing and quantitative RT-PCR revealed that leucine-rich alpha-2-glycoprotein 1 (LRG1) was highly expressed in RUNX3-deficient and dysfunctional LSECs. In in vitro and coculture experiments, RUNX3-depleted LSECs secreted LRG1, which activated hepatic stellate cells via TGFBR1-SMAD2/3 signaling in a paracrine manner. Furthermore, circulating LRG1 levels were elevated in mouse models of liver fibrosis and in patients with fatty liver and cirrhosis. Conclusions RUNX3 deficiency in the endothelium induces LSEC dysfunction, LRG1 secretion, and liver fibrosis progression. Therefore, endothelial RUNX3 is a crucial gatekeeping factor in LSECs, and profibrotic angiocrine LRG1 may be a novel target for combating liver fibrosis. ⓘ Ojha, Uttam; Kim, Somi; Rhee, Chang Yun; You, Jihye; Choi, Yoon Ha; Yoon, Soo-Hyun; Park, Soo Young; Lee, Yu Rim; Kim, Jong Kyoung; Bae, Suk-Chul; Lee, You Mie ⓘ Kyungpook Natl Univ, Coll Pharm, Vessel Organ Interact Res Ctr, VOICE MRC,Res Inst Pharmaceut Sci, Daegu 41566, South Korea; Pohang Univ Sci & Technol POSTECH, Dept Life Sci, Pohang 37673, Gyeongbuk, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Chungbuk Natl Univ, Inst Tumor Res, Sch Med, Dept Biochem, Cheongju 28644, South Korea ⓘ ; Lee, Kyung-Soo/C-9016-2011; You, Jihye/GYD-4786-2022; Kim, SOOCHI/AAD-6959-2020; Kim, Jong/AAF-3414-2021 ⓘ 57192203609; 57670396600; 58829058400; 59215293600; 57208160781; 34968837000; 57191674344; 57194094753; 35201256500; 7202714699; 8230508600 ⓘ uttamojha47@gmail.com; ksomi47@postech.ac.kr; rcyoon2414@gmail.com; jhy9081@gmail.com; true000@postech.ac.kr; yunshh@hanmail.net; psyoung0419@gmail.com; deblue00@naver.com; blkimjk@postech.ac.kr; scbae@cbnu.ac.kr; lym@knu.ac.kr; ⓘ HEPATOLOGY ⓘ HEPATOLOGY ⓘ 0270-9139 1527-3350 81 4 SCIE GASTROENTEROLOGY & HEPATOLOGY ⓘ 2024 15.8 4.4 1.47 2025-05-07 ⓘ 3 4 Liver sinusoidal endothelial cells; RUNX3; LRG1; Liver fibrosis ⓘ ⓘ ⓘ Animals; Core Binding Factor Alpha 3 Subunit; Disease Models, Animal; Endothelial Cells; Glycoproteins; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Knockout; Signal Transduction; STAT3 Transcription Factor; alanine aminotransferase; alpha2 glycoprotein; aspartate aminotransferase; biological marker; cytokine; interleukin 6; Janus kinase; leucine rich alpha 2 glycoprotein 1; Smad2 protein; Smad3 protein; STAT3 protein; thioacetamide; transcription factor RUNX3; transforming growth factor beta receptor 1; unclassified drug; glycoprotein; LRG1 protein, mouse; Runx3 protein, mouse; STAT3 protein; adult; aging; angiogenesis; animal experiment; animal model; animal tissue; Article; coculture; controlled study; cytokine release; disease course; fatty liver; fibrogenesis; hepatic stellate cell; histopathology; human; human tissue; in vitro study; JAK-STAT signaling; liver disease; liver fibrosis; liver function; liver injury; liver sinusoidal endothelial cell; male; mouse; neoplastic cell transformation; nonhuman; pathophysiology; predictive value; protein phosphorylation; real time polymerase chain reaction; serum; signal transduction; single cell RNA seq; survival; animal; disease model; endothelium cell; genetics; knockout mouse; liver; liver cirrhosis; metabolism; pathology ⓘ English 2025 2025-04 10.1097/hep.0000000000001018 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Five-Level Switching-Cell Current Source Inverter Immune to Open-Circuit Fault Issue ⓘ Open-circuit fault (OCF) is the most common and destructive failure among traditional current source converters (CSCs). To address this issue, a topology called immune five-level switching-cell current source inverter (CSI) (I5L-(SCSI)-S-2) is proposed in this article. Furthermore, the proposed circuit avoids the parallel connection of input smoothing inductors (chokes) compared with the different 5L-CSI (D5L-CSI). This modification brings several key advantages: 1) the size/value of one inductor can be dramatically reduced, as its current does not experience low-frequency ripple; 2) tolerance or mismatch in inductor values is no longer a concern, eliminating the need for an additional closed-loop controller; 3) the proposed structure enjoys lower footprint/size in comparison with existing ML-CSIs. Moreover, the proposed inverter features a reduced number of power devices compared to the conventional ML-CSIs, similar to D5L-CSI. The phase-shifted pulse width modulation (PS-PWM) scheme is employed to control the proposed I5L-(SCSI)-S-2, as other modulation methods such as level-shifted, and low/fundamental frequency, or half-cycle PWMs struggle with frequent OCF occurrences. Simulation and experimental results justify the feasibility of the suggested configuration. ⓘ Faraji, Faramarz; Cha, Honnyong ⓘ Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea ⓘ Faraji, Faramarz/J-4074-2019 ⓘ 57191226987; 24450248400 ⓘ faraji.u@gmail.com; chahonny@knu.ac.kr; ⓘ IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS ⓘ IEEE T IND ELECTRON ⓘ 0278-0046 1557-9948 72 2 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION ⓘ 2024 7.2 4.4 0 2025-05-07 ⓘ 0 0 Switches; Inverters; Inductors; Topology; Turning; Voltage control; Semiconductor diodes; Current source inverter; multilevel converter; open-circuit fault; phase-shifted PWM; reliability ⓘ CURRENT-SOURCE CONVERTER; TOPOLOGIES; OPERATION ⓘ Current source inverter; multilevel converter; open-circuit fault; phase-shifted PWM; reliability ⓘ Electric inductors; 'current; Cell current; Current source converters; Current source inverter; Lower frequencies; Multilevel converter; Open-circuit fault; Parallel connections; Phase-shifted PWM; Switching cells; Electric inverters ⓘ English 2025 2025-02 10.1109/tie.2024.3419238 ⓘ 바로가기 바로가기 바로가기 바로가기
○ Article ⓘ Immune-mediated adverse events and overall survival with tremelimumab plus durvalumab and durvalumab monotherapy in unresectable hepatocellular carcinoma: HIMALAYA Phase 3 randomized clinical trial ⓘ Background and Aims: In the global, Phase 3 HIMALAYA study in unresectable hepatocellular carcinoma (HCC), STRIDE significantly improved overall survival (OS) versus sorafenib; durvalumab was noninferior to sorafenib. Immune checkpoint inhibitor studies have shown an association between the occurrence of immune-mediated adverse events (imAEs) and improved OS. We assessed potential associations between the occurrence of imAEs and OS, and temporal patterns of imAEs, in HIMALAYA. Approach and Results: OS in participants who did and did not experience imAEs and the frequency and timing of imAEs were assessed for STRIDE and durvalumab in the safety analysis set of HIMALAYA. imAEs occurred in 139/388 (35.8%) and 64/388 (16.5%) participants with STRIDE and durvalumab, respectively; most were low grade. OS hazard ratios (95% CI) in participants who experienced imAEs versus those who did not were 0.73 (0.56-0.95) for STRIDE and 1.14 (0.82-1.57) for durvalumab. The 36-month OS rate (95% CI) for STRIDE was 36.2% (28.1-46.7) and 27.7% (22.4-34.2) in participants who did and did not experience imAEs, respectively. The most common imAE category with STRIDE was endocrine events (16.5%). Most imAEs occurred ≤3 months after treatment initiation. Conclusions: Participants who experienced imAEs with STRIDE had a numerical improvement in OS versus those who did not, which was not observed for durvalumab. Long-term OS with STRIDE was observed regardless of imAEs. Most imAEs were low grade, manageable, and occurred in the first 3 months after treatment initiation. Results continue to support the benefits of STRIDE in a diverse population that reflects unresectable HCC globally. Copyright © 2025 The Author(s). ⓘ Lau, George; Sangro, Bruno; Cheng, Ann-Lii; Kudo, Masatoshi; Kelley, Robin Kate; Tak, Won Young; Gasbarrini, Antonio; Reig, Maria; Lim, Ho Yeong; Tougeron, David; De Toni, Enrico N.; Tam, Vincent C.; Mody, Kabir; Gong, Jun; Crysler, Oxana V.; Sukeepaisarnjaroen, Wattana; Lipatov, Oleg; Morimoto, Manabu; Archambeaud, Isabelle; Burgio, Valentina; Phuong, Le Thi Tuyet; Chao, Yee; Peron, Jean-Marie; Berres, Marie-Luise; Ko, Yoo-Joung; Ran, Di; Makowsky, Mallory; Negro, Alejandra; Abou-Alfa, Ghassan K. ⓘ Humanity and Health Clinical Trial Center, Humanity and Health Medical Group, Hong Kong; Liver Unit and HPB Oncology Area, Clínica Universidad de Navarra, CIBEREHD, Pamplona, Spain; Department of Oncology, National Taiwan University Cancer Center, National Taiwan University Hospital, Taipei, Taiwan; Department of Gastroenterology and Hepatology, Kindai University, Faculty of Medicine, Osaka, Japan; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, United States; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy; Barcelona Clinic Liver Cancer (BCLC), Liver Unit, Hospital Clinic de Barcelona, IDIBAPS, CIBEREHD, University of Barcelona, Barcelona, Spain; Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea; Department of Gastroenterology and Hepatology, Poitiers University Hospital, Poitiers, France; Department of Medicine II, University Hospital, LMU Munich, Munich, Germany; Department of Oncology, Tom Baker Cancer Centre, University of Calgary, Calgary, AB, Canada; Division of Hematology/Oncology, Department of Medicine, Mayo Clinic, Jacksonville, FL, United States; Department of Medicine, Division of Hematology and Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, United States; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, United States; Department of Medicine, Faculty of Medicine, Khon Kaen University, Srinagarind Hospital, Khon Kaen, Thailand; Department of Oncology, Republican Clinical Oncology Dispensary, Ufa, Russian Federation; Kanagawa Cancer Center, Yokohama, Japan; Institut des Maladies de l’Appareil Digestif (IMAD), Nantes Université, CHU Nantes, Nantes, France; Department of Medical Oncology, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy; People’s Hospital 115, Ho Chi Minh City, Viet Nam; Division of Medical Oncology, Center for Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan; Hepatology Unit, Rangueil University Hospital, Toulouse, France; Clinic of Gastroenterology, Metabolic Diseases and Internal Medicine Intensive Care, University Hospital RWTH Aachen, Aachen, Germany, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany; St Michael’s Hospital, Unity Health Toronto, Toronto, ON, Canada; AstraZeneca, Gaithersburg, MD, United States; AstraZeneca, Gaithersburg, MD, United States, Department of Clinical Development, Erasca, Inc., San Diego, CA, United States; AstraZeneca, Gaithersburg, MD, United States; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States, Weill Medical College, Cornell University, New York, NY, United States, Trinity College Dublin, Dublin, Ireland ⓘ ⓘ 7102301257; 7004456732; 58237223500; 55216757300; 17635112900; 59802036700; 58589716200; 26025138700; 59896698600; 15761619500; 8704814700; 8545813300; 36620397400; 55921073600; 57206784067; 6505802234; 55294786600; 7202520397; 37074052000; 57203689237; 59905422000; 7402865850; 7007062453; 12809026200; 7401677379; 59905545600; 57294837100; 58436283800; 8660213800 ⓘ abou-alg@mskcc.org; ⓘ Hepatology ⓘ HEPATOLOGY ⓘ 0270-9139 1527-3350 SCIE GASTROENTEROLOGY & HEPATOLOGY ⓘ 2024 15.8 4.4 0 2025-06-11 ⓘ 0 ⓘ ⓘ anti-CTLA-4; anti-PD-L1; immune checkpoint inhibitors; safety; survival ⓘ ⓘ English Article in press 2025 10.1097/hep.0000000000001385 ⓘ 바로가기 바로가기 바로가기
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