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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Progressive NO2 Sensors with Rapid Alarm and Persistent Memory-Type Responses for Wide-Range Sensing Using Antimony Triselenide Nanoflakes | Antimony triselenide (Sb2Se3) nanoflake-based nitrogen dioxide (NO2) sensors exhibit a progressive bifunctional gas-sensing performance, with a rapid alarm for hazardous highly concentrated gases, and an advanced memory-type function for low-concentration (<1 ppm) monitoring repeated under potentially fatal exposure. Rectangular and cuboid shaped Sb2Se3 nanoflakes, comprising van der Waals planes with large surface areas and covalent bond planes with small areas, can rapidly detect a wide range of NO2 gas concentrations from 0.1 to 100 ppm. These Sb2Se3 nanoflakes are found to be suitable for physisorption-based gas sensing owing to their anisotropic quasi-2D crystal structure with extremely enlarged van der Waals planes, where they are humidity-insensitive and consequently exhibit an extremely stable baseline current. The Sb2Se3 nanoflake sensor exhibits a room-temperature/low-voltage operation, which is noticeable owing to its low energy consumption and rapid response even under a NO2 gas flow of only 1 ppm. As a result, the Sb2Se3 nanoflake sensor is suitable for the development of a rapid alarm system. Furthermore, the persistent gas-sensing conductivity of the sensor with a slow decaying current can enable the development of a progressive memory-type sensor that retains the previous signal under irregular gas injection at low concentrations. | Kim, Young Been; Jung, Sung Hyeon; Kim, Dong Su; Deshpande, Nishad G.; Suh, Hee Won; Lee, Hak Hyeon; Choi, Ji Hoon; Lee, Ho Seong; Cho, Hyung Koun | Sungkyunkwan Univ SKKU, Sch Adv Mat Sci & Engn, 2066 Seobu Ro, Suwon 16419, Gyeonggi Do, South Korea; Indian Inst Informat Technol, Surat 395007, India; Kyungpook Natl Univ, Sch Adv Mat Sci & Engn, 80 Daehak Ro, Daegu 41566, South Korea; Sungkyunkwan Univ SKKU, Res Ctr Adv Mat Technol, 2066 Seobu Ro, Suwon 16419, Gyeonggi Do, South Korea | 김, 동수/IAN-1770-2023; Cho, Hyung/P-2007-2017; Cho, Hyung Koun/P-2007-2017; Deshpande, Nishad/D-1021-2011 | 57193847828; 57200660299; 57209168253; 56096311600; 57222623083; 57923457900; 57218377818; 55706810400; 35236454300 | chohk@skku.edu; | ADVANCED FUNCTIONAL MATERIALS | ADV FUNCT MATER | 1616-301X | 1616-3028 | 31 | 38 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2021 | 19.924 | 4.7 | 1.72 | 2025-07-30 | 37 | 32 | antimony triselenide; memory-type sensing; nanoflake structures; NO; (2) gas sensors; room-temperature recovery | GALLIUM-ZINC-OXIDE; GAS SENSOR; NITROGEN-DIOXIDE; DETECTION LIMITS; SMALL MOLECULES; PHYSISORPTION; ADSORPTION; EXPOSURE; SCALE | antimony triselenide; memory-type sensing; nanoflake structures; NO <sub>2</sub> gas sensors; room-temperature recovery | Alarm systems; Chemical detection; Chemical sensors; Crystal structure; Energy utilization; Flow of gases; Gas detectors; Gases; Nitrogen oxides; Selenium compounds; Van der Waals forces; Large surface area; Low concentrations; Low energy consumption; Nitrogen dioxides; Persistent memory; Potentially fatal; Range sensing; Rapid response; Antimony compounds | English | 2021 | 2021-09 | 10.1002/adfm.202102439 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Sampled-parameter dependent stabilization for linear parameter varying systems with asynchronous parameter sampling | In this paper, we propose a new sampled-data stabilization method for linear parameter-varying (LPV) systems with asynchronous parameter sampling. A sampled-parameter-dependent controller is designed by considering the sampling of parameters as well as that of states. Based on a newly proposed sampled-parameter-dependent looped-functional (SPDLF), a relaxed linear matrix inequality (LMI) condition in the parameterized stabilization criteria is derived by considering the deviation bound between the continuous-time parameter of the plant and the sampled parameter. Finally, numerical examples are provided to demonstrate the effectiveness of the proposed method. | Han, Seungyong; Lee, Sangmoon | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | Han, Seungyong/AAN-8632-2021; Lee, Sangmoon/C-4502-2018 | 57200991395; 59510733500 | moony@knu.ac.kr; | INTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL | INT J ROBUST NONLIN | 1049-8923 | 1099-1239 | 31 | 8 | SCIE | AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;MATHEMATICS, APPLIED | 2021 | 3.897 | 4.7 | 0.59 | 2025-07-30 | 12 | 10 | looped‐ functional; LPV systems; parameterized LMI technique; sampled‐ data control | looped-functional; LPV systems; parameterized LMI technique; sampled-data control | Continuous time systems; Linear matrix inequalities; Linear systems; Numerical methods; Continuous-time; Linear parameter varying systems; Parameterized; Sampled data stabilization; Sampled parameters; Stabilization criteria; Stabilization | English | 2021 | 2021-05-25 | 10.1002/rnc.5454 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Thinning prediction of hole-expansion test for DP980 sheet based on a non-associated flow rule | The hole expansion process is widely used in automotive engineering to produce various car parts (e.g., lower arm, trailing arm, control arm, and chassis parts). A numerical study of the hole expansion test for the 3rd generation of advanced high-strength steel sheets is an attractive research topic because of the sheets high strength and low formability. This study presents a numerical prediction of the thinning behaviors observed in the hole expansion test for a DP980 sheet using finite element analysis. The experimental data of the tested material obtained from several standard testing methods, including uniaxial tensile, biaxial tensile, and hole expansion tests, are freely supported in the NUMISHEET 2018 conference Benchmark 01. Accordingly, several material models have been developed based on non-associated flow rule (NAFR) by using Hill's quadratic, YId2000-2d, and Yoshida polynomial functions to describe the yield and potential surfaces of the tested material. In addition, the KimTuan hardening model is adopted to correctly represent the stress-strain relationship until large strains. Hence, a user-defined material subroutine (UMAT) is developed in Abaqus/Standard package to simulate hole expansion tests using these developed material models. The simulation results reveal that adopting the NAFR theory in the finite element analysis is an efficient method of simulating the hole expansion test. Additionally, the accuracy of the potential surface plays a crucial role in the thinning behavior prediction in the hole expansion simulation. The experimental data obtained from the plane-strain tension tests are recommended for use in calibrating the yield function parameters. | Kim, Jin Jae; Quoc Tuan Pham; Kim, Young Suk | Kyungpook Natl Univ, Grad Sch, Daegu 41566, South Korea; Ton Duc Thang Univ, Div Computat Math & Engn, Inst Computat Sci, Ho Chi Minh City, Vietnam; Ton Duc Thang Univ, Fac Civil Engn, Ho Chi Minh City, Vietnam; Kyungpook Natl Univ, Sch Mech Engn, Daegu 41566, South Korea | Pham, Quoc Tuan/AAH-8010-2019; Kim, Sang-Hoon/AAA-2248-2020 | 57209555877; 57191753992; 36065820800 | jinjaekim@knu.ac.kr;phamquoctuan@tdtu.edu.vn;caekim@knu.ac.kr; | INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES | INT J MECH SCI | 0020-7403 | 1879-2162 | 191 | SCIE | ENGINEERING, MECHANICAL;MECHANICS | 2021 | 6.772 | 4.7 | 2.34 | 2025-07-30 | 34 | 37 | Hole expansion test; Advanced high strength steel; Anisotropic yield function; Finite element analysis; Non-associated flow rule | ANISOTROPIC YIELD FUNCTIONS; ALUMINUM-ALLOY SHEETS; LIMIT CURVE; STEEL SHEET; DEFORMATION; METALS; IDENTIFICATION; FLANGEABILITY; FORMABILITY; SIMULATION | Advanced high strength steel; Anisotropic yield function; Finite element analysis; Hole expansion test; Non-associated flow rule | ABAQUS; Advanced high strength Steel; Forecasting; High strength steel; Strain; Stress-strain curves; Tensile testing; Behavior prediction; Non-associated flow rule; Numerical predictions; Plane strain tension; Polynomial functions; Potential surfaces; Stress-strain relationships; Uniaxial tensile; Finite element method | English | 2021 | 2021-02-01 | 10.1016/j.ijmecsci.2020.106067 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | An episode of detectable serum hepatitis B virus-DNA level does not affect risk of hepatic decompensation among untreated compensated cirrhosis patient with viral load of <2, 000 IU/ml | Lee, Hye Won; Park, Soo Young; Lee, Yu Rim; Lee, Jae Seung; Kim, Seung Up; Park, Jun Yong; Kim, Do Young; Ahn, Sang Hoon; Kim, Beom Kyung | Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Internal Med, Daegu, South Korea | SANG-HOON, AHN/AAV-2600-2020; Park, Jun/H-7127-2019; Kim, Yoon/G-6633-2015; LEE, JAE SEUNG/KHT-9575-2024; Kim, Sun/L-4239-2013 | beomkkim@yuhs.ac; | JOURNAL OF HEPATOLOGY | J HEPATOL | 0168-8278 | 1600-0641 | 75 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 30.083 | 4.8 | 1 | Compensated cirrhosis; hepatitis B virus; low-level viremia; decompensation; antiviral therapy | English | 2021 | 2021-07 | 바로가기 | 바로가기 | ||||||||||||||
| ○ | Meeting Abstract | ARO-HSD reduces hepatic HSD17B13 mRNA expression and protein levels in patients with suspected NASH | Gane, Edward; Schwabe, Christian; Yoon, Ki Tae; Heo, Jeong; Scott, Russell; Lee, Jeonghoon; Lee, Jung Il; Kweon, Young Oh; Weltman, Martin; Harrison, Stephen; Tetri, Brent; Cusi, Kenneth; Loomba, Rohit; Christianson, Dawn; Rajicic, Natasa; San Martin, Javier; Hamilton, James; Mak, Lung Yi Loey; Yuen, Man-Fung | Univ Auckland, Auckland, New Zealand; New Zealand Clin Res, Auckland, New Zealand; Pusan Natl Univ, Yangsan Hosp, Yangsan, South Korea; Pusan Natl Univ, Busan, South Korea; Med Res Inst, Busan, South Korea; Christchurch Hosp, Lipid & Diabet Res, Christchurch, New Zealand; Seoul Natl Univ Hosp, Seoul, South Korea; Gangnam Severance Hosp, Seoul, South Korea; Kyungpook Natl Univ, Daegu, South Korea; Nepean Hosp, Penrith, NSW, Australia; Pinnacle Clin Res Ctr, San Antonio, TX USA; St Louis Univ, Sch Med, St Louis, MO USA; Univ Florida, Gainesville, FL USA; UCSD, NAFLD Res Ctr, La Jolla, CA USA; Arrowhead Pharmaceut Inc, Pasadena, CA USA; Univ Hong Kong, Queen Mary Hosp, Hong Kong, Peoples R China | Yuen, Richard Man Fung/C-4466-2009; Loomba, Rohit/AAE-7831-2019; Gane, Edward/AGN-7071-2022; Harrison, Stephen/GON-3283-2022; Heo, Jeong/MHQ-1390-2025; Mak, Lung Yi (Loey)/ABB-1599-2020; Cusi, Kenneth/ADV-2401-2022 | jhamilton@arrowheadpharma.com; | JOURNAL OF HEPATOLOGY | J HEPATOL | 0168-8278 | 1600-0641 | 75 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 30.083 | 4.8 | 4 | English | 2021 | 2021-07 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Effect of beta-blocker therapy in patients with or without left ventricular systolic dysfunction after acute myocardial infarction | Aims This observational study aimed to investigate the association between beta-blocker therapy and clinical outcomes in patients with acute myocardial infarction (AMI), especially with mid-range or preserved left ventricular systolic function. Methods and results Among 13 624 patients enrolled in the Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH), 12 200 in-hospital survivors were selected. Patients with beta-blockers showed significantly lower 1-year major adverse cardiac events (MACE), which was a composite of cardiac death, MI, revascularization, and readmission due to heart failure [9.7 vs. 14.3/100 patient-year; hazard ratio (HR) 0.84, 95% confidence interval (CI) 0.72-0.97; P=0.022). However, this association had a significant interaction with left ventricular ejection fraction (LVEF). Beta-blocker therapy at discharge was associated with lower 1-year MACE in patients with LVEF = 50% (HR 1.16, 95% CI 0.91-1.48; P=0.234). Conclusions Beta-blocker therapy at discharge was associated with better 1-year clinical outcomes in patients with reduced or mid-range LVEF after AMI, but not in patients with preserved LVEF. These data suggested that the long-term beta-blocker therapy may be guided by LVEF. | Joo, Seung-Jae; Kim, Song-Yi; Choi, Joon-Hyouk; Park, Hyeung Keun; Beom, Jong Wook; Lee, Jae-Geun; Chae, Shung Chull; Kim, Hyo-Soo; Kim, Young Jo; Cho, Myeong Chan; Kim, Chong Jin; Rha, Seung-Woon; Yoon, Junghan; Jeong, Myung Ho | Jeju Natl Univ, Dept Internal Med, Sch Med, Jeju, South Korea; Jeju Natl Univ Hosp, Dept Internal Med, Jeju, South Korea; Jeju Natl Univ, Dept Hlth Policy & Management, Sch Med, Jeju, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Yeungnam Univ Med Ctr, Dept Internal Med, Daegu, South Korea; Chungbuk Natl Univ Hosp, Dept Internal Med, Cheongju, South Korea; Kyunghee Univ Hosp Gangdong, Dept Internal Med, Seoul, South Korea; Korea Univ, Cardiovasc Ctr, Guro Hosp, Seoul, South Korea; Wonju Severance Christian Hosp, Dept Internal Med, Wonju, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Gwangju, South Korea | Lee, Jungmin/KHT-2438-2024; Park, Hui/J-6839-2012; Kim, Song-Yi/JAC-5358-2023; Kim, Jin Sug/AAY-6890-2021; choi, jo/O-5940-2014; Kim, Hyo/J-2753-2012; Rha, Seung-Woon/AGE-5810-2022 | 9236504200; 35740671300; 56459207600; 35215968100; 56054900800; 57208710816; 7101962036; 33567809200; 57189907572; 7401727518; 35229511500; 8569030400; 35760728900; 56485157500 | sejjoo@jejunu.ac.kr; | EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY | EUR HEART J-CARD PHA | 2055-6837 | 2055-6845 | 7 | 6 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS;PHARMACOLOGY & PHARMACY | 2021 | 11.177 | 4.8 | 3.8 | 2025-07-30 | 45 | 51 | Beta-blockers; Myocardial infarction; Ventricular ejection fraction; Outcome | PRESERVED EJECTION FRACTION; CORONARY-ARTERY-DISEASE; ST-SEGMENT ELEVATION; CLINICAL-OUTCOMES; HEART-FAILURE; GUIDELINES; ESC | Beta-blockers; Myocardial infarction; Outcome; Ventricular ejection fraction | Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Stroke Volume; Treatment Outcome; Ventricular Function, Left; beta adrenergic receptor blocking agent; acute heart infarction; aged; Article; clinical outcome; cohort analysis; controlled study; disease association; drug effect; female; heart death; heart failure; heart infarction; heart muscle revascularization; hospital discharge; hospital readmission; human; left ventricular systolic dysfunction; major adverse cardiac event; major clinical study; male; observational study; outcome assessment; patient care; survivor; adverse event; complication; heart infarction; heart left ventricle function; heart stroke volume; percutaneous coronary intervention; treatment outcome | English | 2021 | 2021-11 | 10.1093/ehjcvp/pvaa029 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Meeting Abstract | Efficacy, safety, and tolerability of seladelpar in patients with compensated liver cirrhosis due to primary biliary cholangitis (PBC): a pooled analysis of phase 2 and phase 3 studies | Gordon, Stuart C.; Trivedi, Palak; Bowlus, Christopher; Michael, Galambos; Goel, Aparna; Gulamhusein, Aliya; Levy, Cynthia; Neff, Guy; Stanca, Carmen; Thorburn, Douglas; Bacon, Bruce; Borg, Brian; Doerffel, Yvonne; Forman, Lisa; Freilich, Bradley; Gheorghe, Liana; Gonzalez, Maria Sarai; Harrison, Stephen; Huang, Jonathan; Jeong, Sook-Hyang; Kim, Seung Up; Lake, John; Odin, Joseph; Tak, Won Young; Tobias, Hillel; Vierling, John M.; Yang, Ke; Steinberg, Alexandra (Sasha); Choi, Yun-Jung; McWherter, Charles; Mayo, Marlyn J. | Henry Ford Hlth Syst, Detroit, MI USA; Univ Hosp Birmingham, Birmingham, W Midlands, England; Univ Calif Davis, Med Ctr, Sacramento, CA 95817 USA; Digest Healthcare Georgia, Atlanta, GA USA; Stanford Hosp, Stanford, CA USA; Toronto Gen Hosp, Toronto, ON, Canada; Univ Miami, Miami, FL USA; Covenant Res, Sarasota, FL USA; NYU Langone Hlth, New York, NY USA; Royal Free Hosp, London, England; St Louis Univ, Sch Med, St Louis, MO USA; Jackson Liver & GI Specialists, Jackson, MS USA; Charite, Berlin, Germany; Univ Colorado, Aurora, CO USA; Kansas City Res Inst, Kansas City, KS USA; Fundeni Clin Inst, Bucharest, Romania; Consultorio Doctora Maria Sarai Gonzalez Huezo, Metepec, Mexico; Pinnacle Clin Res, San Antonio, TX USA; Univ Rochester, Rochester, NY 14627 USA; Seoul Natl Univ, Bundang Hosp, Seongnam Si, South Korea; Yonsei Univ Hlth Syst, Severance Hosp, Seoul, South Korea; Univ Minnesota, Minneapolis, MN USA; Mt Sinai Hosp, New York, NY 10029 USA; Kyungpook Natl Univ Hosp, Daegu, South Korea; Concorde Med Grp, New York, NY USA; Baylor Coll Med, Houston, TX 77030 USA; CymaBay Therapeut, Newark, CA USA; Univ Texas Southwestern, Dallas, TX USA | Borg, Brian/A-5512-2011; Harrison, Stephen/GON-3283-2022; Bowlus, Christopher/N-9276-2016; Kim, Sun/L-4239-2013; Jeong, Sook-Hyang/J-5642-2012; Simona, Gheorghe/AAD-6897-2021 | ychoi@cymabay.com; | JOURNAL OF HEPATOLOGY | J HEPATOL | 0168-8278 | 1600-0641 | 75 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 30.083 | 4.8 | 0 | English | 2021 | 2021-07 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Meeting Abstract | Long-term Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) in Children with Chronic Hepatitis B (CHB): Final Results from a Placebo-Controlled Trial | Chang, Mei-Hwei; Bezerra, Jorge; Choe, Byung-Ho; Pacurar, Daniela; Nijhawan, Sandeep; Park, Jae Hong; Mehta, Rajiv; Choe, Yon Ho; Flaherty, John F.; Nguyen, Anh-Hoa; Liu, Yang; Constantinescu, Alexandrina; Rosenthal, Philip; Kim, Kyung Mo; Leung, Daniel Hao Bin | Natl Taiwan Univ Hosp, Taipei, Taiwan; Cincinnati Childrens Hosp, Cincinnati, OH USA; Kyungpook Natl Univ, Daegu, South Korea; Grigore Alexandrescu Emergency Clin Hosp Children, Inst Med & Pharm, Bucharest, Romania; Sawai Man Singh Hosp, SMS Med Coll, Jaipur, Rajasthan, India; Pusan Natl Univ, Childrens Hosp, Pusan, South Korea; Surat Inst Med Sci SIDS, Surat, India; Sungkyunkwan Univ, Sch Med, Seoul, South Korea; Gilead Sci Inc, 353 Lakeside Dr, Foster City, CA 94404 USA; Fundeni Clin Inst, Bucharest, Romania; Univ Calif San Francisco, San Francisco, CA 94143 USA; Asan Med Ctr Childrens Hosp, Ulsan Coll Med, Seoul, South Korea; Texas Childrens Hosp, Baylor Coll Med, Houston, TX 77030 USA | Rosenthal, Philip/AGG-3493-2022; Pacurar, Daniela/IYS-1131-2023; Choe, Byung-Ho/KSM-6251-2024 | john.flaherty@gilead.com; | JOURNAL OF HEPATOLOGY | J HEPATOL | 0168-8278 | 1600-0641 | 75 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 30.083 | 4.8 | 1 | English | 2021 | 2021-07 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Practical guidance for P2Y12 inhibitors in acute myocardial infarction undergoing percutaneous coronary intervention | Aims Potent P2Y12 inhibitors for dual antiplatelet therapy (DAPT) is crucial for managing acute myocardial infarction; however, the selection of drugs is based on limited clinical information such as age and body weight. The current study sought to develop and validate a new risk scoring system that can be used to guide the selection of potent P2Y12 inhibitors by balancing ischaemic benefit and bleeding risk. Methods and results Derivation cohort of 10 687 patients who participated in the Korea Acute Myocardial Infarction Registry-National Institutes of Health study was used to construct a new scoring system. We combined the ischaemic and bleeding models to establish a simple clinical prediction score. Among the tow score group (n= 1764), the observed bleeding risk (8.7% vs. 4.4%, P <0.001) due to potent P2Y12 inhibitors exceeded ischaemic benefit (1.3% vs. 2.2%, P= 0.185) during 12 months. Conversely, the high score group (n = 1898) showed an overall benefit from taking potent P2Y12 inhibitors from the standpoint of observed ischaemic (17.1% vs. 8.6%, P < 0.001) and bleeding events (10.1% vs. 6.8%, P= 0.073). The performance of ischaemic [integrated area under the curve (iAUC) = 0.809] and bleeding model (iAUC = 0.655) was deemed to be acceptable. Conclusion The new scoring system is a useful clinical tool for guiding DAPT by balancing ischaemic benefit and bleeding risk, especially among Asian populations. Further validation studies with other cohorts will be required to verify that the new system meets the needs of real clinical practice. | Lee, Seung Hun; Kim, Hyun Kuk; Jeong, Myung Ho; Yasuda, Satoshi; Honda, Satoshi; Jeong, Young-Hoon; Lee, Joo Myung; Hahn, Joo-Yong; Kang, Jeehoon; Chae, Shung Chull; Seong, In-Whan; Park, Jong-Seon; Chae, Jei Keon; Hur, Seung-Ho; Cha, Kwang Soo; Kim, Hyo-Soo; Seung, Ki-Bae; Rha, Seung-Woon; Hwang, Jin-Yong; Choi, Dong-Ju; Oh, Seok Kyu; Kim, Sung Soo; Park, Taek Kyu; Yang, Jeong Hoon; Song, Young Bin; Choi, Seung-Hyuk; Gwon, Hyeon-Cheol | Chonnam Natl Univ Hosp, Dept Cardiol, 42 Jaebong Ro, Gwangju 61469, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Heart Vasc Stroke Inst, Dept Internal Med,Sch Med,Div Cardiol, 81 Irwon Ro, Seoul 06351, South Korea; Chosun Univ Hosp, Dept Cardiol, 365 Pilmun Daero, Gwangju 61453, South Korea; Natl Cerebral & Cardiovasc Ctr, Dept Cardiovasc Med, 6-1 Kishibe Shimmachi, Suita, Osaka 5648565, Japan; Gyeongsang Natl Univ, Dept Internal Med, Changwon Hosp, 11 Samjeongja Ro, Changwon 51472, Japan; Seoul Natl Univ Hosp, Cardiovasc Ctr, Dept Internal Med, 101 Daehak Ro, Seoul 03080, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Chungnam Natl Univ, Chungnam Natl Univ Hosp, Coll Med, Dept Internal Med, 282 Munhwa Ro, Daejeon 35015, South Korea; Yeungnam Univ, Med Ctr, Dept Internal Med, Div Cardiol,Coll Med, 170 Hyeonchung Ro, Daegu 42415, South Korea; Chonbuk Natl Univ, Dept Internal Med, Div Cardiol, Med Sch, 20 Geonji Ro, Jeonju 54907, South Korea; Keimyung Univ, Dept Internal Med, Div Cardiol, Dongsan Med Ctr, 6 Dalseong Ro, Daegu 41932, South Korea; Pusan Natl Univ Hosp, Dept Internal Med, Div Cardiol, 179 Gudeok Ro, Busan 49241, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Cardiol Div, 222 Banpo Daero, Seoul 06591, South Korea; Korea Univ, Cardiovasc Ctr, Dept Internal Med, Div Cardiol,Guro Hosp, 148 Gurodong Ro, Seoul 08308, South Korea; Gyeonsang Natl Univ, Gyeongsang Natl Univ Hosp, Dept Internal Med, Sch Med, 79 Gangnam Ro, Jinju 52727, South Korea; Seoul Natl Univ, Cardiovasc Ctr, Dept Internal Med, Bundang Hosp, 82 Gumi Ro 173beon Gil, Seongnam 13620, South Korea; Wonkwang Univ, Dept Internal Med, Div Cardiol, Sch Med, 460 Iksandae Ro, Iksan 54538, South Korea | Song, Young Bin/IYJ-6953-2023; Honda, Satoshi/GXG-5198-2022; Lee, Jae/J-5597-2012; choi, sun ryoung/AGZ-1893-2022; Jeong, Young-Hoon/F-3476-2015; Rha, Seung-Woon/AGE-5810-2022; Hahn, Joo-Yong/AAU-7250-2020; Lee, Seung/AAW-6430-2021; Kim, Seok-Hwan/G-9981-2015; Choi, Dong-Ju/J-5686-2012; Kim, Hyo/J-2753-2012; Yasuda, Satoshi/K-5503-2017 | 57203597270; 57206210646; 56485157500; 7202845632; 56177424700; 24758957500; 54894745500; 12771661800; 55139508800; 7101962036; 35254371300; 15763054600; 26029709000; 34570274500; 7102837700; 33567809200; 7003964208; 8569030400; 55892914700; 35274349200; 24734336000; 57015155300; 55750570800; 45662209400; 15763569500; 57213560615; 6603262426 | myungho@chollian.net;yasuda.satoshi.hp@ncvc.go.jp; | EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY | EUR HEART J-CARD PHA | 2055-6837 | 2055-6845 | 7 | 2 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS;PHARMACOLOGY & PHARMACY | 2021 | 11.177 | 4.8 | 1.19 | 2025-07-30 | 8 | 13 | Myocardial infarction; Percutaneous coronary intervention; Risk assessment; Platelet aggregation inhibitors; Prognosis | ASSOCIATION TASK-FORCE; ANTIPLATELET THERAPY; PLATELET INHIBITION; FOCUSED UPDATE; CLOPIDOGREL; MANAGEMENT; GUIDELINES; OUTCOMES; TICAGRELOR; RATIONALE | Myocardial infarction; Percutaneous coronary intervention; Platelet aggregation inhibitors; Prognosis; Risk assessment | Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists; United States; acetylsalicylic acid; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; calcium channel blocking agent; clopidogrel; dipeptidyl carboxypeptidase inhibitor; hydroxymethylglutaryl coenzyme A reductase inhibitor; prasugrel; purinergic P2Y receptor antagonist; purinergic P2Y12 receptor antagonist; ticagrelor; unclassified drug; acute heart infarction; adult; aged; Article; clinical practice; cohort analysis; controlled study; drug choice; drug efficacy; drug potency; drug safety; dual antiplatelet therapy; female; human; loading drug dose; major clinical study; male; outcome assessment; percutaneous coronary intervention; risk benefit analysis; scoring system; South Korea; treatment duration; validation study; heart infarction; percutaneous coronary intervention; practice guideline; United States | English | 2021 | 2021-03 | 10.1093/ehjcvp/pvaa005 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Meeting Abstract | Safety, efficacy, and pharmacodynamic (PD) activity of 12 weeks treatment with oral RIG-I agonist, inarigivir (IRIG), plus 48 weeks of tenofovir alafenamide in adult patients with chronic hepatitis B: a phase 2 collaboration study | Lim, Young-Suk; Hui, Aric J.; Jang, Jeong-Won; Tak, Won-Young; Ahn, Sang Hoon; Jang, Byoung Kuk; Tsang, Tak Yin Owen; Kim, Won; Yang, Jenny; Chen, Diana; McDonald, Circe; Zhang, Liao; Gaggar, Anuj; Gao, Bing; Byun, Kwan Soo; Lee, Kwan Sik; Yim, Hyung Joon; Chan, Henry L. Y. | Univ Ulsan, Coll Med Seoul Korea, Asan Med Ctr, Seoul, South Korea; Alice Ho Miu Ling Nethersole Hosp, Hong Kong, Peoples R China; Catholic Univ Korea, Seoul St Marys Hosp, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Kyungpook Natl Univ Hosp, Daegu, South Korea; Yonsei Univ, Coll Med, Seoul, South Korea; Keimyung Univ, Dong Sang Hosp, Daegu, South Korea; Princess Margaret Hosp, Hong Kong, Peoples R China; Seoul Natl Univ, Boramae Med Ctr, Seoul Metropolitan Govt, Seoul, South Korea; Gilead Sci Inc, 353 Lakeside Dr, Foster City, CA 94404 USA; Korea Univ, Coll Med, Guro Hosp, Seoul, South Korea; Yonsei Univ, Coll Med, Gangnam Severance Hosp, Seoul, South Korea; Korea Univ, Ansan Hosp, Ansan, Gyeonggi Do, South Korea; Prince Wales Hosp, Hong Kong, Peoples R China | Lim, Young-Suk/AFQ-5165-2022; Lee, Shin-Jae/D-5883-2012; Jang, Jeong/LOS-2890-2024; Yang, Jenny/KCJ-6006-2024; Tsang, Owen/AGS-0035-2022; Chan, Henry/B-9636-2008; Kim, Won/H-6940-2019; SANG-HOON, AHN/AAV-2600-2020 | jenny.yang@gilead.com; | JOURNAL OF HEPATOLOGY | J HEPATOL | 0168-8278 | 1600-0641 | 75 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 30.083 | 4.8 | 0 | English | 2021 | 2021-07 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Meeting Abstract | The artificial intelligence-driven model for prediction of hepatocellular carcinoma development in chronic hepatitis B patients: Derivation and validation using 11, 111 patients from Asian and Caucasian cohorts | Kim, Hwi Young; Lampertico, Pietro; Nam, Joon Yeul; Lee, Hyung-Chul; Kim, Seung Up; Jang, Eun Sun; Lee, Han Ah; Park, Soo Young; Seo, Yeon Seok; Lim, Young-Suk; Dalekos, George; Idilman, Ramazan; Sypsa, Vana; Berg, Thomas; Buti, Maria; Calleja Panero, Jose Luis; Goulis, Ioannis; Manolakopoulos, Spilios; Janssen, Harry; Lee, Yun Bin; Cho, Eun Ju; Yu, Su Jong; Kim, Yoon Jun; Yoon, Jung-Hwan; Papatheodoridis, George; Lee, Jeonghoon | Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Fdn IRCCS Ca Granda Osped Maggiore Policlin, Div Gastroenterol & Hepatol, CRC AM & A Migliavacca Ctr Liver Dis, Milan, Italy; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Liver Res Inst, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Anesthesiol, Coll Med, Seoul, South Korea; Yonsei Univ, Coll Med, Dept Internal Med, Severance Hosp, Seoul, South Korea; Yonsei Univ, Coll Med, Yonsei Liver Ctr, Severance Hosp, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Coll Med, Seoul, South Korea; Korea Univ, Dept Internal Med, Anam Hosp, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Internal Med, Seoul, South Korea; Gen Univ Hosp Larissa, Dept Med, Natl Expertise Ctr Greece Autoimmune Liver Dis, Larisa, Greece; Gen Univ Hosp Larissa, Res Lab Internal Med, Natl Expertise Ctr Greece Autoimmune Liver Dis, Larisa, Greece; Ankara Univ, Dept Gastroenterol, Sch Med, Ankara, Turkey; Natl & Kapodistrian Univ Athens, Dept Hyg Epidemiol & Med Stat, Sch Med, Athens, Greece; Univ Leipzig, Dept Med 2, Div Hepatol, Med Ctr, Leipzig, Germany; Hosp Gen Univ Vall Hebron, Barcelona, Spain; Ciberehd, Barcelona, Spain; Hosp Univ Puerta Hierro, IDIPHIM, CIBERehd, Barcelona, Spain; Aristotle Univ Thessaloniki, Dept Internal Med 4, Gen Hosp Thessaloniki Hippokratio, Sch Med, Thessaloniki, Greece; Natl & Kapodistrian Univ Athens, Gen Hosp Athens Hippokratio, Dept Internal Med 2, Sch Med, Athens, Greece; Univ Hlth Network, Toronto Western & Gen Hosp, Liver Clin, Toronto, ON, Canada; Natl & Kapodistrian Univ Athens, Sch Med, Dept Gastroenterol, Gen Hosp Athens Laiko, Athens, Greece | Idilman, Ramazan/AFL-0461-2022; Kiemeney, Lambertus/D-3357-2009; SYPSA, VANA/A-5082-2008; Buti, MARIA/A-5327-2019; Lim, Young-Suk/AFQ-5165-2022; Lee, Jeong-Hoon/Q-1055-2018; Kim, Eun Young/JCE-3602-2023; Lee, Yoojin/AAB-9799-2022; Kim, Yoon/J-2746-2012; Yoon, Jung/J-5563-2012; Manolakopoulos, Spilios/AAD-7058-2019; Kim, Heui-Soo/ABF-3773-2021; Panero, Jose/A-5351-2010; Kim, Sun/L-4239-2013; Papatheodoridis, George/A-4603-2008; Lee, Hyung-Chul/U-1910-2019 | pindra@empal.com; | JOURNAL OF HEPATOLOGY | J HEPATOL | 0168-8278 | 1600-0641 | 75 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 30.083 | 4.8 | 0 | English | 2021 | 2021-07 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Correction | OceanGliders: A Component of the Integrated GOOS (vol 6, 422, 2019) | Testor, Pierre; de Young, Brad; Rudnick, Daniel L.; Glenn, Scott; Hayes, Daniel; Lee, Craig M.; Pattiaratchi, Charitha; Hill, Katherine; Heslop, Emma; Turpin, Victor; Alenius, Pekka; Barrera, Carlos; Barth, John A.; Beaird, Nicholas; Becu, Guislain; Bosse, Anthony; Bourrin, Francois; Brearley, J. Alexander; Chao, Yi; Chen, Sue; Chiggiato, Jacopo; Coppola, Laurent; Crout, Richard; Cummings, James; Curry, Beth; Curry, Ruth; Davis, Richard; Desai, Kruti; DiMarco, Steve; Edwards, Catherine; Fielding, Sophie; Fer, Ilker; Frajka-Williams, Eleanor; Gildor, Hezi; Goni, Gustavo; Gutierrez, Dimitri; Haugan, Peter; Hebert, David; Heiderich, Joleen; Henson, Stephanie; Heywood, Karen; Hogan, Patrick; Houpert, Loic; Huh, Sik; Inall, Mark E.; Ishii, Masso; Ito, Shin-ichi; Itoh, Sachihiko; Jan, Sen; Kaiser, Jan; Karstensen, Johannes; Kirkpatrick, Barbara; Klymak, Jody; Kohut, Josh; Krahmann, Gerd; Krug, Marjolaine; McClatchie, Sam; Marin, Frederic; Mauri, Elena; Mehra, Avichal; Meredith, Michael P.; Meunier, Thomas; Miles, Travis; Morell, Julio M.; Mortier, Laurent; Nicholson, Sarah; O'Callaghan, Joanne; O'Conchubhair, Diarmuid; Oke, Peter; Pallas-Sanz, Enric; Palmer, Matthew; Park, JongJin; Perivoliotis, Leonidas; Poulain, Pierre-Marie; Perry, Ruth; Queste, Bastien; Rainville, Luc; Rehm, Eric; Roughan, Moninya; Rome, Nicholas; Ross, Tetjana; Ruiz, Simon; Saba, Grace; Schaeffer, Amandine; Schonau, Martha; Schroeder, Katrin; Shimizu, Yugo; Sloyan, Bernadette M.; Smeed, David; Snowden, Derrick; Song, Yumi; Swart, Sebastian; Tenreiro, Miguel; Thompson, Andrew; Tintore, Joaquin; Todd, Robert E.; Toro, Cesar; Venables, Hugh; Wagawa, Taku; Waterman, Stephanie; Watlington, Roy A.; Wilson, Doug | UPMC Univ Pierre & Marie Curie, Lab Oceanog & Climatol LOCEAN, Inst Pierre Simon Laplace IPSL,Observ Ecce Terra, Sorbonne Univ,Paris 06,CNRS,IRD,MNHN,UMR 7159, Paris, France; Mem Univ Newfoundland, Mem Univ, Dept Phys & Phys Oceanog, St John, NF, Canada; Scripps Inst Oceanog, San Diego, CA USA; Rutgers State Univ, Dept Marine & Coastal Sci, New Brunswick, NJ USA; Univ Cyprus OC UCY, Oceanog Ctr, Nicosia, Cyprus; Univ Washington, Appl Phys Lab, Seattle, WA 98105 USA; Univ Western Australia, Oceans Grad Sch, Perth, WA, Australia; World Meteorol Org, Geneva, Switzerland; UNESCO, Paris, France; Finnish Meteorol Inst, Helsinki, Finland; Ocean Platform Canary Isl, Telde, Spain; Oregon State Univ, Coll Earth Ocean & Atmospher Sci, Corvallis, OR 97331 USA; Takuvik, Quebec City, PQ, Canada; Univ Bergen, Geophys Inst, Bergen, Norway; CEFREM, Perpignan, France; British Antarctic Survey, Cambridge, England; Seatrec, Monrovia, CA USA; Naval Res Lab, Monterey, CA USA; CNR, Inst Marine Sci ISMAR, Venice, Italy; Sorbonne Univ, Inst Mer Villefranche IMEV, Lab Oceanog Villefranche LOV, CNRS,Inst Mer Villefranche IMEV,UMR7093, Villefranche Sur Mer, France; Naval Res Lab, Stennis, MS USA; Bermuda Inst Ocean Sci, St George, Bermuda; Dalhousie Univ, Dept Oceanog, Halifax, NS, Canada; OceanLeadership, Washington, DC USA; Texas A&M Univ, Dept Oceanog, College Stn, TX 77843 USA; Univ Georgia, Skidaway Inst Oceanog, Athens, GA 30602 USA; Natl Oceanog Ctr, Southampton, Hants, England; Hebrew Univ Jerusalem, Inst Earth Sci, Jerusalem, Israel; NOAA, Atlantic Oceanog & Meteorol Lab, Miami, FL 33149 USA; Inst Sea Peru, Callao, Peru; Inst Marine Res, Bergen, Norway; Bedford Inst Oceanog, Dept Fisheries & Oceans, Dartmouth, NS, Canada; MIT, 77 Massachusetts Ave, Cambridge, MA 02139 USA; Woods Hole Oceanog Inst, Woods Hole, MA 02543 USA; Univ East Anglia, Sch Environm Sci, Ctr Ocean & Atmospher Sci, Norwich, Norfolk, England; United States Naval Res Lab, Washington, DC USA; Scottish Assoc Marine Sci, Oban, Argyll, Scotland; Korea Inst Ocean Sci & Technol, Ansan, South Korea; Meteorol Res Inst, Tsukuba, Ibaraki, Japan; Univ Tokyo, Atmosphere & Ocean Res Inst, Chiba, Japan; Natl Taiwan Univ, Inst Oceanog, Taipei, Taiwan; GEOMAR Helmholtz Ctr Ocean Res Kiel, Kiel, Germany; Gulf Mexico Coastal Ocean Observing Syst, College Stn, TX USA; Univ Victoria, Ocean Phys Grp, Victoria, BC, Canada; CSIR, Cape Town, South Africa; FishOcean Enterprises, Auckland, New Zealand; LEGOS IRD, Toulouse, France; Ist Nazl Oceanog & Geofis Sperimentale, Trieste, Italy; NOAA, Natl Ctr Environm Predict, College Pk, MD USA; Ensenada Ctr Sci Res & Higher Educ, Ensenada, Baja California, Mexico; Univ Puerto Rico, Dept Marine Sci, Mayaguez, PR 00709 USA; ENSTA LOCEAN, Palaiseau, France; Natl Inst Water & Atmospher Res, Wellington, New Zealand; Marine Inst, Galway, Ireland; CSIRO, Oceans & Atmosphere, Hobart, Tas, Australia; Kyungpook Natl Univ, Sch Earth Syst Sci, Daegu, South Korea; Hellenic Ctr Marine Res, Iraklion, Greece; Ctr Maritime Res & Experimentat, La Spezia, Italy; Shell, Houston, TX USA; Univ New South Wales, Sch Math & Stat, Sydney, NSW, Australia; Inst Ocean Sci, Dept Fisheries & Oceans, Sidney, BC, Canada; CSIC UIB, Inst Mediterraneo Estudios Avanzados, Esporles, Spain; Appl Ocean Sci, Fairfax Stn, VA USA; NOAA, Washington, DC USA; Univ Gothenburg, Dept Marine Sci, Gothenburg, Sweden; Univ Cape Town, Dept Oceanog, Cape Town, South Africa; CALTECH, Pasadena, CA 91125 USA; SOCIB, Palma De Mallorca, Spain; IMEDEA CSIC UIB, Palma De Mallorca, Spain; IOCARIBE, IOC UNESCO, Paris, France; Japan Fisheries Res & Educ Agcy, Yokohama, Kanagawa, Japan; Univ British Columbia, Dept Earth Ocean & Atmospher Sci, Vancouver, BC, Canada; Caribbean Coastal Ocean Observing Syst, Mayaguez, PR USA | Frajka-Williams, Eleanor/H-2415-2011; Ross, Tetjana/E-4073-2010; Pattiaratchi, Charitha/E-6916-2011; Smeed, David/B-4726-2012; Krug, Marjolaine/F-2559-2012; Sloyan, Bernadette/N-8989-2014; Inall, Mark/I-4835-2014; schroeder, katrin/C-7490-2009; Ruiz, Simon/N-9164-2019; Schroeder, Katrin/C-7490-2009; Ito, Shin-ichi/E-2981-2012; Bourrin, François/F-4909-2010; Oke, Peter/C-5127-2011; Roughan, Moninya/B-5563-2009; Miles, Travis/L-7918-2013; Gildor, Hezi/AAZ-6602-2021; Mauri, Elena/LWH-9402-2024; Fielding, Sophie/E-5137-2012; Klymak, Jody/A-3041-2008; Coppola, Laurent/F-7880-2017; Kaiser, Jan/D-3327-2009; Sanz, Enric/I-1451-2015; Houpert, Loïc/A-4841-2012; Rudnick, Daniel/J-8948-2016; Fer, Ilker/C-7820-2012; Brearley, Alexander/C-3313-2012; Karstensen, Johannes/A-8534-2013; Tenreiro, M./F-4453-2018; Goni, Gustavo/D-2017-2012; Waterman, Stephanie/AAY-6033-2020; Todd, Robert/T-3536-2018; Schaeffer, Amandine/AAW-5476-2021; Chiggiato, Jacopo/JMP-7670-2023; Henson, Stephanie/AAC-9709-2019 | 8894760600; 57224439671; 57206128440; 57200941381; 25926485300; 55541588900; 7003884923; 7402618129; 45761240800; 57198861097; 6602323539; 23007638700; 7202739425; 55553803900; 6504225653; 55670102100; 15130542100; 54951045000; 59838709200; 57142590900; 7801471032; 7005150506; 6701549893; 7402590762; 37096972000; 7102120740; 57203066328; 57208644259; 6603903828; 16030370100; 57189229179; 6602426672; 57526637600; 6603390592; 6603993619; 7005194566; 7003819789; 58348993200; 57203576993; 8071539200; 7003373288; 7103139129; 55443684000; 7101832925; 6602137873; 57220838625; 55728573100; 7403114780; 24831926300; 7402184800; 6603418610; 8761642800; 6602755372; 7003621794; 6602423682; 55344912300; 55900754600; 7103141099; 6603885750; 7101835389; 7103271119; 35778635800; 36857219400; 7006211106; 7003312252; 57191163444; 26536512300; 57215880528; 6603581190; 9741767700; 57210804491; 55717016100; 6506887529; 7103266181; 56071469300; 54894353600; 6602288805; 24074741400; 6603755030; 57194293890; 56354972300; 7102650640; 30267978100; 37102552400; 56662095800; 57199846892; 57215881695; 6603096267; 6603688117; 25723879900; 57215880242; 16481564100; 13907939600; 57209409285; 7003580674; 34168474000; 16246932800; 22836719000; 25822726500; 8308408600; 6505899083; 57215880793 | testor@locean-ipsl.upmc.fr; | FRONTIERS IN MARINE SCIENCE | FRONT MAR SCI | 2296-7745 | 8 | SCIE | MARINE & FRESHWATER BIOLOGY | 2021 | 5.247 | 4.9 | 0 | 2025-07-30 | 0 | 0 | in situ ocean observing systems; gliders; boundary currents; storms; water transformation; ocean data management; autonomous oceanic platforms; GOOS | autonomous oceanic platforms; boundary currents; gliders; GOOS; in situ ocean observing systems; ocean data management; storms; water transformation | English | 2021 | 2021-05-24 | 10.3389/fmars.2021.696100 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Comparison of the Efficacy and Safety of Tacrolimus and Low-Dose Corticosteroid with High-Dose Corticosteroid for Minimal Change Nephrotic Syndrome in Adults | Background Tacrolimus is used as a steroid-sparing immunosuppressant in adults with minimal change nephrotic syndrome. However, combined treatment with tacrolimus and low-dose steroid has not been compared with high-dose steroid for induction of clinical remission in a large-scale randomized study. Methods In this 24-week open-label noninferiority study, we randomized 144 adults with minimal change nephrotic syndrome to receive 0.05 mg/kg twice-daily tacrolimus plus once-daily 0.5mg/kg prednisolone, or once-daily 1 mg/kg prednisolone alone, for up to 8 weeks or until achieving complete remission. Two weeks after complete remission, we tapered the steroid to a maintenance dose of 5-7.5 mg/d in both groups until 24 weeks after study drug initiation. The primary end point was complete remission within 8 weeks (urine protein: creatinine ratio, 3.0 g/g) after complete remission to within 24 weeks of study drug initiation. Results Complete remission within 8 weeks occurred in 53 of 67 patients (79.1%) receiving tacrolimus and low-dose steroid and 53 of 69 patients (76.8%) receiving high-dose steroid; this difference demonstrated noninferiority, with an upper confidence limit below the predefined threshold (20%) in both intent-to-treat (11.6%) and per-protocol (17.0%) analyses. Groups did not significantly differ in time until remission. Significantly fewer patients relapsed on maintenance tacrolimus (3-8 ng/ml) plus tapered steroid versus tapered steroid alone (5.7% versus 22.6%, respectively; P=0.01). There were no clinically relevant safety differences. Conclusions Combined tacrolimus and low-dose steroid was noninferior to high-dose steroid for complete remission induction in adults with minimal change nephrotic syndrome. Relapse rates were significantly lower with maintenance tacrolimus and steroid compared with steroid alone. No clinically-relevant differences in safety findings were observed. | Chin, Ho Jun; Chae, Dong-Wan; Kim, Yong Chul; An, Won Suk; Ihm, ChunGyoo; Jin, Dong-Chan; Kim, Sung Gyun; Kim, Yong-Lim; Kim, Yong-Soo; Kim, Yoon-Goo; Koo, Ho Seok; Lee, Jung Eun; Lee, Kang Wook; Oh, Jieun; Park, Jung Hwan; Jiang, Hongsi; Lee, Hyuncheol; Lee, Sang Koo | Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Dong A Univ, Dept Internal Med, Coll Med, Busan, South Korea; Kyung Hee Univ, Dept Nephrol, Med Ctr, Seoul, South Korea; St Vincent Hosp, Dept Internal Med, Suwon, South Korea; Hallym Univ, Dept Internal Med, Sacred Heart Hosp, Anyang, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Internal Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Med, Seoul, South Korea; Inje Univ, Dept Internal Med, Seoul Paik Hosp, Seoul, South Korea; Chungnam Natl Univ Hosp, Dept Nephrol, Daejeon, South Korea; Kangdong Sacred Heart Hosp, Dept Internal Med, Seoul, South Korea; Konkuk Univ, Dept Internal Med, Med Ctr, Seoul, South Korea; Astellas Pharma Singapore Pte Ltd, Med Affairs Asia Oceania, Singapore, Singapore; Astellas Pharma Korea Inc, Clin Res, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Dept Internal Med, 88 Olymp Ro,43 Gil, Seoul 138736, South Korea | Chin, Ho/J-5678-2012; Kim, Yong-Lim/AGK-3172-2022; Kim, Yong/L-8653-2019; Kim, Hyun-Jung/ABA-3655-2021; Kim, Soo-Yeon/ADR-9663-2022; Chae, Dong-Wan/J-5681-2012; lee, je/O-6247-2014; Kim, Hyo Yeol/HLP-5150-2023 | 23495522400; 23471686900; 57026583000; 57215052077; 35602084200; 57216531078; 34770030300; 55633533600; 57225107409; 36063940300; 56888361500; 58034512300; 7501514537; 8409118400; 56682283600; 7404465729; 57221227408; 27172104900 | sklee2@amc.seoul.kr; | JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | J AM SOC NEPHROL | 1046-6673 | 1533-3450 | 32 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 14.981 | 5.0 | 1.95 | 2025-07-30 | 15 | 17 | corticosteroid; glomerulonephritis; nephrotic syndrome; immunosuppression; tacrolimus; remission | CHANGE NEPHROPATHY; CHANGE DISEASE; CYCLOSPORINE; RESISTANT; THERAPY; PREDNISOLONE; RELAPSE; PROTEINURIA; REMISSION | Adolescent; Adrenal Cortex Hormones; Adult; Aged; Drug Administration Schedule; Humans; Immunosuppressive Agents; Medication Adherence; Middle Aged; Nephrosis, Lipoid; Patient Safety; Prednisolone; Recurrence; Remission Induction; Republic of Korea; Tacrolimus; Treatment Outcome; Young Adult; albumin; aspartate aminotransferase; bilirubin; cholesterol; corticosteroid; creatinine; hemoglobin; low density lipoprotein cholesterol; prednisolone; protein; tacrolimus; triacylglycerol; corticosteroid; immunosuppressive agent; prednisolone; tacrolimus; abdominal pain; adult; alopecia; Article; bilirubin blood level; body weight change; bronchitis; cholesterol blood level; clinical trial; controlled study; corticosteroid therapy; coughing; creatinine blood level; creatinine urine level; cystitis; diarrhea; drug megadose; drug withdrawal; dyspepsia; edema; erythrocyte count; face edema; female; follow up; generalized edema; headache; heart palpitation; hematocrit; hematuria; hemoglobin blood level; herpes zoster; human; infestation; low drug dose; major clinical study; male; medication compliance; multicenter study; nephrotic syndrome; neurologic disease; oliguria; open study; paresthesia; pneumonia; pollakisuria; priority journal; protein urine level; randomized controlled trial; recurrence free survival; relapse; remission; respiratory tract disease; rhinopharyngitis; survival rate; treatment duration; triacylglycerol blood level; tuberculosis; adolescent; aged; comparative study; drug administration; lipoid nephrosis; middle aged; patient safety; recurrent disease; South Korea; treatment outcome; young adult | English | 2021 | 2021-01 | 10.1681/asn.2019050546 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | GDF-15 Predicts In-Hospital Mortality of Critically Ill Patients with AKI Requiring Continuous Renal Replacement Therapy: Results from a Prospective Randomized Controlled Trial | Lim, Jeong-Hoon; Noh, Hee Won; Jeon, Soojee; Kim, Sejoong; Jung, Hee-Yeon; Choi, Ji-Young; Park, Sun-Hee; Kim, Chan-Duck; Kim, Yong-Lim; Cho, Jang-Hee | Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Seoul Natl Univ, Bundang Hosp, Seongnam, South Korea | Jung, Hee-Yeon/AFB-8578-2022; Kim, Sejoong/J-5356-2015; Kim, Yong-Lim/AGK-3172-2022; Lim, Jeong-Hoon/ABE-6003-2020; Park, Sun-Hee/LMN-0033-2024 | JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | J AM SOC NEPHROL | 1046-6673 | 1533-3450 | 32 | 10 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 14.981 | 5.0 | 0 | English | 2021 | 2021-10 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Meeting Abstract | Higher Serum Total Cholesterol to High-Density Lipoprotein Cholesterol Ratio Was Associated with Increased Mortality Among Incident Peritoneal Dialysis Patients | Noh, Hee Won; Jeon, Soojee; Lim, Jeong-Hoon; Jung, Hee-Yeon; Choi, Ji-Young; Park, Sun-Hee; Kim, Chan-Duck; Kim, Yong-Lim; Cho, Jang-Hee | Kyungpook Natl Univ Hosp, Daegu, South Korea | Lim, Jeong-Hoon/ABE-6003-2020; Jung, Hee-Yeon/AFB-8578-2022; Kim, Yong-Lim/AGK-3172-2022; Park, Sun-Hee/LMN-0033-2024 | JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | J AM SOC NEPHROL | 1046-6673 | 1533-3450 | 32 | 10 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 14.981 | 5.0 | 0 | English | 2021 | 2021-10 | 바로가기 | 바로가기 |
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