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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Biological Living Standards of Korea during the Port-Opening Period, 1876-1910 | After several hundred years of a closed-door policy, Korea finally opened its ports in 1876. Historians have traditionally claimed that the port-opening was coerced by foreign countries, deteriorated the Korean economy, and led to Korea becoming a colony. We examined this view by measuring biological living standards and find the opposite. The height of the male Hangryu Deceased, who died on the street but whose bodies were not claimed, increased by 1.1 cm from the 1880s to the 1910s. This also implies that free trade rather than new institutions might matter more for economic growth during the colonial era. | Kim, Duol; Park, Heejin | Myongji Univ, Dept Econ, 34 Geobulgol Ro, Seoul 03674, South Korea; Kyungpook Natl Univ, Sch Econ & Trade, 80 Daehak Ro, Daegu 41566, South Korea | 16052818100; 55713612100 | duolkim@mju.ac.kr;heejinp@knu.ac.kr; | JOURNAL OF ECONOMIC HISTORY | J ECON HIST | 0022-0507 | 1471-6372 | 81 | 2 | SSCI;AHCI | ECONOMICS;HISTORY OF SOCIAL SCIENCES;HISTORY | 2021 | 2.459 | 4.4 | 0.71 | 2025-07-30 | 1 | 2 | COLONIAL KOREA; CHINA; HEIGHT; STATURE; JAPAN | Korea; economic growth; economic history; free trade; living standard; nineteenth century; port operation | English | 2021 | 2021-06 | 10.1017/s0022050721000115 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Numerical study on rheology of two-dimensional dry foam | We study the mechanical response of two-dimensional aqueous foams subjected to an oscillating shear strain using numerical simulations based on the immersed boundary method. Foams have unique rheological properties ranging from solid-like to fluid-like. They have an elastic property under a small strain with a linear stress-strain relationship. As the strain increases, the foams undergo topological rearrangements with a sudden release of energy and stress. Then the energy-strain and stress-strain curves exhibit hysteresis behaviors under the oscillating shear strain, and the macroscopic response of foams changes from a viscoelastic solid to a viscoelastic fluid. These wide-ranging dynamical responses of foams result from avalanches of topological rearrangements which are concentrated in a single localized region. This is called a shear localization, and we investigate the effect of the topological rearrangements and the shear localization on the rheology of foams. | Kim, Dokyum; Seol, Yunchang; Kim, Yongsam | Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Natl Chiao Tung Univ, Shing Tung Yau Ctr, 1001 Univ Rd, Hsinchu 30010, Taiwan | 58839393600; 55277174800; 7410207566 | dkkyum@cau.ac.kr;ycseol@knu.ac.kr;kimy@cau.ac.kr; | PHYSICS OF FLUIDS | PHYS FLUIDS | 1070-6631 | 1089-7666 | 33 | 5 | SCIE | MECHANICS;PHYSICS, FLUIDS & PLASMAS | 2021 | 4.98 | 4.4 | 0.6 | 2025-07-30 | 8 | 9 | QUASI-STATIC RHEOLOGY; SIMPLE SHEARING FLOW; SOAP FROTH; STRESS; AVALANCHES; DYNAMICS | Elasticity; Numerical methods; Shear flow; Shear strain; Topology; Turbulent flow; Viscoelasticity; Immersed boundary methods; Linear stress strain relationship; Macroscopic response; Rheological property; Shear localizations; Topological rearrangements; Vis-coelastic fluids; Viscoelastic solids; Stress-strain curves | English | 2021 | 2021-05 | 10.1063/5.0050010 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Strontium ions capturing in aqueous media using exfoliated titanium aluminum carbide (Ti2AlC MAX phase) | The etching of MAX phases using hydrofluoric acid (HF) is not environmentally-friendly. Therefore, in this study, a MAX phase named Ti2AlC was synthesized and etched using a green hydrothermal alkalization approach, resulting in nanofibers (Alk-Ti2Cfibr) and sheet-like (Alk-Ti2Csheet) nanostructures. Nanostructures with exceptional physicochemical properties with an excessive number of active binding moieties were deployed to remove radioactive strontium ions (Sr2+) from matrices, such as deionized (DI), tape, and seawater. The synthesized nanostructures were characterized using analytical techniques, including X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy, and infrared spectroscopy. The synthesized nanostructures were highly stable in water, unlike other HF-etched MX-enes, possess a unique structure, large surface area, and are enriched with oxygenated terminal groups. Sr2+ adsorption performance of nanofibers and nanosheets was evaluated in typical batch tests. The nanostructure unveiled a maximum adsorption capacity of 296.46 mg/g, which is among the maximum removal capacity reported for similar removal, including identical graphene oxide and its composites. Additionally, in seawater, Sr2+ adsorption capacity was 3543.33 mu g/g with more than 95% removal efficiency. The adsorption mechanism study confirms the electrostatic interactions between Alk-Ti2Csheet and Sr2+. (C) 2021 Elsevier B.V. All rights reserved. | Shahzad, Asif; Oh, Jae-Min; Rasool, Kashif; Jang, Jiseon; Kim, Bolam; Lee, Dae Sung | Dongguk Univ Seoul, Dept Energy & Mat Engn, Seoul 04620, South Korea; Hamad Bin Khalifa Univ HBKU, Qatar Fdn, Qatar Environm & Energy Res Inst, POB 5824, Doha, Qatar; Korea Radioact Waste Agcy, R&D Inst Radioact Wastes, 174 Gajeong Ro, Daejeon 34129, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea | ; Rasool, Kashif/AAN-6671-2020 | 57190382338; 7402155053; 28767865000; 56611137400; 57208922438; 55568524907 | daesung@knu.ac.kr; | JOURNAL OF NUCLEAR MATERIALS | J NUCL MATER | 0022-3115 | 1873-4820 | 549 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;NUCLEAR SCIENCE & TECHNOLOGY | 2021 | 3.555 | 4.4 | 1.55 | 2025-07-30 | 17 | 21 | MAX phase; Alk-Ti2C nanostructure; radionuclide; strontium; alkalization; radioactive waste | alkalization; Alk–Ti<sub>2</sub>C nanostructure; MAX phase; radioactive waste; radionuclide; strontium | Deionized water; Etching; Graphene; Infrared spectroscopy; Nanocomposites; Nanofibers; Nanostructures; Radioactive wastes; Radioactivity; Scanning electron microscopy; Strontium; X ray photoelectron spectroscopy; Adsorption capacities; Alkalization; Alk–ti2C nanostructure; Aqueous media; MAX-phase; Sheet-like; Strontium ion; Synthesised; Ti$-2$/AlC; Titanium aluminum carbide; Adsorption | English | 2021 | 2021-06 | 10.1016/j.jnucmat.2021.152916 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Enabling the Selective Detection of Endocrine-Disrupting Chemicals via Molecularly Surface-Imprinted "Coffee Rings" | Molecularly imprinted polymers (MIPs) represent an intriguing class of synthetic materials that can selectively recognize and bind chemical or biological molecules in a variety of value-added applications in sensors, catalysis, drug delivery, antibodies, and receptors. In this context, many advanced methods of implementing functional MIP materials have been actively studied. Herein, we report a robust strategy to produce highly ordered arrays of surface-imprinted polymer patterns with unprecedented regularity for MIP-based sensor platform, which involves the controlled evaporative self-assembly process of MIP precursor solution in a confined geometry consisting of a spherical lens on a flat Si substrate (i.e., sphere-on-flat geometry) to synergistically utilize the "coffee-ring" effect and repetitive stick-slip motions of the three-phase contact line simply by solvent evaporation. Highly ordered arrays of the ring-patterned MIP films are then polymerized under UV irradiation to achieve semi-interpenetrating polymer networks. The extraction of templated target molecules from the surface-imprinted ring-patterned MIP films leaves behind copious cavities for the recognizable specific "memory sites" to efficiently detect small molecules. As a result, the elaborated surface structuring effect, sensitivity, and specific selectivity of the coffee-ring-based MIP sensors are scrutinized by capitalizing on an endocrine-disrupting chemical, 2,4-dichlorophenoxyacetic acid (2,4-D), as an example. Clearly, the evaporative self-assembly of nonvolatile solutes in a confined geometry renders the creation of familiar yet ordered coffee-ring-like patterns for a wide range of applications, including sensors, scaffolds for cell motility, templates, substrates for neuron guidance, etc., thereby dispensing with the need of multistep lithography techniques and external fields. | Lee, Jihye; Yang, Jin Chul; Lone, Saifullah; Park, Woon Ik; Lin, Zhiqun; Park, Jinyoung; Hong, Suck Won | Pusan Natl Univ, Coll Nanosci & Nanotechnol, Dept Cognomechatron Engn, Dept Opt & Mechatron Engn, Busan 46241, South Korea; Kyungpook Natl Univ, Sch Appl Chem Engn, Dept Polymer Sci & Engn, Daegu 41566, South Korea; Pukyong Natl Univ, Dept Mat Sci & Engn, Busan 48513, South Korea; Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA | ; Lone, Saifullah/AAT-7811-2020; Lin, Zhiqun/GPF-4115-2022; PARK, JUN-YOUNG/P-5981-2015 | 55689992200; 56381794400; 35206357900; 53980463200; 8237419000; 57286293400; 57252820400 | jinpark@knu.ac.kr;swhong@pusan.ac.kr; | BIOMACROMOLECULES | BIOMACROMOLECULES | 1525-7797 | 1526-4602 | 22 | 4 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, ORGANIC;POLYMER SCIENCE | 2021 | 6.979 | 4.5 | 0.52 | 2025-07-30 | 9 | 9 | POLYMERS; PATTERNS; SENSOR | Coffee; Endocrine Disruptors; Molecular Imprinting; Polymerization; Polymers; Chemical detection; Chemicals; Controlled drug delivery; Geometry; Interpenetrating polymer networks; Irradiation; Lithography; Magnetic bubbles; Molecules; Polymer films; Scaffolds (biology); Slip forming; Stick-slip; Substrates; 2,4 dichlorophenoxyacetic acid; endocrine disruptor; molecularly imprinted polymer; polymer; 2 ,4-dichlorophenoxyacetic acid (2 ,4-D); Endocrine disrupting chemicals; Highly ordered arrays; Molecularly Imprinted Polymer; Self assembly process; Semi-interpenetrating polymer networks; Three-phase contact line; Value added applications; Article; atomic force microscopy; cell adhesion; cell motility; controlled study; geometry; human; molecular imprinting; nerve cell; priority journal; quartz crystal microbalance; surface area; surface property; surface tension; ultraviolet irradiation; viscosity; coffee; polymerization; Endocrine disrupters | English | 2021 | 2021-04-12 | 10.1021/acs.biomac.0c01748 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Management of adverse events in patients with acute myeloid leukemia in remission receiving oral azacitidine: experience from the phase 3 randomized QUAZAR AML-001 trial | Background Most older patients with acute myeloid leukemia (AML) who attain morphologic remission with intensive chemotherapy (IC) will eventually relapse and post-relapse prognosis is dismal. In the pivotal QUAZAR AML-001 trial, oral azacitidine maintenance therapy significantly prolonged overall survival by 9.9 months (P = 55 years with AML and intermediate- or poor-risk cytogenetics at diagnosis, who had attained first complete remission (CR) or CR with incomplete blood count recovery (CRi) within 4 months before study entry, were randomized 1:1 to receive oral azacitidine 300 mg or placebo once-daily for 14 days in repeated 28-day cycles. Safety was assessed in all patients who received >= 1 dose of study drug. Results A total of 469 patients received oral azacitidine (n = 236) or placebo (n = 233). Median age was 68 years. Patients received a median of 12 (range 1-80) oral azacitidine treatment cycles or 6 (1-73) placebo cycles. Gastrointestinal AEs were common and typically low-grade. The most frequent grade 3-4 AEs during oral azacitidine therapy were hematologic events. AEs infrequently required permanent discontinuation of oral azacitidine (13%), suggesting they were effectively managed with use of concomitant medications and oral azacitidine dosing modifications. Conclusion Oral azacitidine maintenance had a generally favorable safety profile. Prophylaxis with antiemetic agents, and blood count monitoring every other week, are recommended for at least the first 2 oral azacitidine treatment cycles, and as needed thereafter. Awareness of the type, onset, and duration of common AEs, and implementation of effective AE management, may maximize treatment adherence and optimize the survival benefits of oral azacitidine AML remission maintenance therapy. Trial registration This trial is registered on clinicaltrials.gov: NCT01757535 as of December 2012. | Ravandi, Farhad; Roboz, Gail J.; Wei, Andrew H.; Dohner, Hartmut; Pocock, Christopher; Selleslag, Dominik; Montesinos, Pau; Sayar, Hamid; Musso, Maurizio; Figuera-Alvarez, Angela; Safah, Hana; Tse, William; Sohn, Sang Kyun; Hiwase, Devendra; Chevassut, Timothy; Pierdomenico, Francesca; La Torre, Ignazia; Skikne, Barry; Bailey, Rochelle; Zhong, Jianhua; Beach, C. L.; Dombret, Herve | Univ Texas MD Anderson Canc Ctr, Dept Leukemia, 1515 Holcombe Blvd, Houston, TX 77030 USA; Weill Cornell Med, New York, NY USA; NewYork Presbyterian Hosp, New York, NY USA; Alfred Hosp, Dept Clin Haematol, Melbourne, Vic, Australia; Mona Sh Univ, Australian Ctr Blood Dis, Melbourne, Vic, Australia; Ulm Univ Hosp, Dept Internal Med 3, Ulm, Germany; Kent & Canterbury Hosp, Canterbury, Kent, England; AZ Sint Jan Brugge Oostende AV, Brugge, Belgium; Hosp Univ & Politecn La Fe, Valencia, Spain; Indiana Univ, Canc Ctr, Indianapolis, IN USA; La Maddalena Casa Cura, Palermo, Italy; Hosp Univ La Princesa, Madrid, Spain; Tulane Univ, Hlth Sci Ctr, New Orleans, LA USA; Univ Louisville, Sch Med, Louisville, KY 40292 USA; Kyungpook Natl Univ Hosp, Daegu, South Korea; Royal Adelaide Hosp, Adelaide, SA, Australia; Brighton & Sussex Med Sch, Brighton, E Sussex, England; Portuguese Inst Oncol Lisbon, Lisbon, Portugal; Celgene Bristol Myers Squibb Co, Boudry, Switzerland; Univ Kansas, Med Ctr, Kansas City, KS 66103 USA; Bristol Myers Squibb, Princeton, NJ USA; Hop St Louis, Assistance Publ Hop Paris AP HP, Paris, France; Univ Paris, Inst Rech St Louis, Paris, France | ; Döhner, Hartmut/C-8933-2016; Ravandi, Farhad/GOH-3538-2022; Wei, Andrew/F-3707-2012; Montesinos, Pau/GYU-2673-2022 | 6603796758; 6602798229; 8565989000; 35374055900; 6602851002; 57209769864; 22986003400; 26654938900; 7004668689; 57225039235; 6602597065; 58378856400; 13310226800; 35344986000; 6506197829; 55216322500; 6603163873; 7004479247; 57237293300; 57190870489; 8346823700; 7005981249 | fravandi@mdanderson.org; | JOURNAL OF HEMATOLOGY & ONCOLOGY | J HEMATOL ONCOL | 1756-8722 | 14 | 1 | SCIE | HEMATOLOGY;ONCOLOGY | 2021 | 23.168 | 4.5 | 0.86 | 2025-07-30 | 17 | 16 | Oral azacitidine; CC-486; Safety; Maintenance | CONVENTIONAL CARE REGIMENS; QUALITY-OF-LIFE; MYELODYSPLASTIC SYNDROMES; MAINTENANCE THERAPY; CC-486; AML; CHEMOTHERAPY; RECOMMENDATIONS; ADHERENCE; DIAGNOSIS | CC-486; Maintenance; Oral azacitidine; Safety | Administration, Oral; Aged; Aged, 80 and over; Anemia; Antimetabolites, Antineoplastic; Azacitidine; Disease Management; Female; Gastrointestinal Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Placebo Effect; Remission Induction; Thrombocytopenia; aciclovir; antiemetic agent; azacitidine; ciprofloxacin; esomeprazole; granisetron; hemoglobin; infusion fluid; levofloxacin; metoclopramide; omeprazole; ondansetron; pantoprazole; proton pump inhibitor; antineoplastic antimetabolite; azacitidine; acute myeloid leukemia; adult; aged; anemia; Article; awareness; blood cell count; blood transfusion; cancer regression; clinical trial; constipation; controlled study; cytogenetics; diarrhea; drug dose comparison; drug efficacy; drug safety; flow cytometry; fluorescence in situ hybridization; gastrointestinal disease; gene mutation; human; leukemia remission; leukocyte count; maintenance therapy; major clinical study; Medical Dictionary for Regulatory Activities; multiple cycle treatment; nausea; neutropenia; neutrophil count; outcome assessment; overall survival; phase 3 clinical trial; platelet count; progression free survival; prophylaxis; quality of life; randomized controlled trial; thrombocytopenia; vomiting; acute myeloid leukemia; anemia; disease management; female; gastrointestinal disease; male; middle aged; neutropenia; oral drug administration; placebo effect; remission; thrombocytopenia; very elderly | English | 2021 | 2021-08-28 | 10.1186/s13045-021-01142-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Vertical-crystalline Fe-doped β-Ni oxyhydroxides for highly active and stable evolution reaction | The layered transition metal oxyhydroxides have received increasing interest owing to the efficient energy conversion performance and material stability during the oxygen evolution reaction (OER). In particular, Fe-doped NiOOH has shown record-high OER performance in alkaline media among various catalysts. Theoretically, undercoordinated facets including Ni4+, exposed at the edges of NiOOH, were predicted to perform highly active OER. Therefore, here we suggest a rational catalyst design, a vertical-crystalline beta-Fe/NiOOH layer built on faceted Fe/Ni nanocrystals, which exposes Ni4+ sites and could improve the OER performance dramatically. Electrochemical OER tests recorded the overpotential of 210 mV at a current density of 10 mA cm(-2) GEO and stable operation for 5 days. In situ/operando and density functional theory studies revealed that the Ni valence cycle between +2 and +4 assisted by Fe dopant is the key engine that greatly accelerates OER kinetics and that the vertical-crystalline beta-Fe/NiOOH layers on Ni octahedra are stable under harsh OER conditions. | Kim, Byeongyoon; Kabiraz, Mrinal Kanti; Lee, Jaewan; Choi, Changhyeok; Baik, Hionsuck; Jung, Yousung; Oh, Hyung-Suk; Choi, Sang-Il; Lee, Kwangyeol | Korea Univ, Dept Chem, Seoul 02841, South Korea; Korea Univ, Res Inst Nat Sci, Seoul 02841, South Korea; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea; Korea Adv Inst Sci & Technol KAIST, Dept Chem & Biomol Engn BK21 4, Daejeon 34141, South Korea; Korea Basic Sci Inst KBSI, Seoul 02841, South Korea; Korea Inst Sci & Technol KIST, Clean Energy Res Ctr, Seoul 02841, South Korea; Kyung Hee Univ, KHU KIST, Dept Conversing Sci & Technol, Seoul 02447, South Korea; Kyungpook Natl Univ, Dept Hydrogen & Renewable Energy, Daegu 41566, South Korea | Kabiraz, Mrinal/AAE-6381-2020; Oh, Hyung-Suk/AID-0267-2022; Kim, Byeongyoon/T-3659-2018; Choi, Sang-Il/AGR-1133-2022; Lee, Kwangyeol/A-9269-2010; Jung, Yousung/D-1676-2010 | 55532693200; 57201400780; 58366672400; 57189905855; 7101961237; 7402506401; 57755728400; 56167600800; 8510322900 | ysjn@kaist.ac.kr;hyung-suk.oh@kist.re.kr;sichoi@knu.ac.kr;kylee1@korea.ac.kr; | MATTER | MATTER-US | 2590-2393 | 2590-2385 | 4 | 11 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY | 2021 | 19.967 | 4.5 | 2.44 | 2025-07-30 | 58 | 57 | MEMBRANE WATER ELECTROLYSIS; OXYGEN-EVOLUTION; ELECTRONIC-STRUCTURE; REACTION DYNAMICS; REDOX STATES; CATALYSTS; ELECTROCATALYSTS; OXIDE; OXIDATION; XANES | active sites; AEMWE; crystalline Fe/NiOOH; DFT study for Fe/NiOOH; electrocatalysis; facet control; heteroepitaxy; in-situ/operando XAS; MAP4: Demonstrate; oxygen evolution reaction | Catalysts; Density functional theory; Design for testability; Electrocatalysis; Energy conversion; Iron compounds; Oxygen; Transition metals; Active site; AEMWE; Crystalline fe/NiOOH; DFT study; DFT study for fe/NiOOH; Facet control; Fe-doped; In-situ/operando XAS; MAP4: demonstrate; Operando; Nickel compounds | English | 2021 | 2021-11-03 | 10.1016/j.matt.2021.09.003 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Dysfunction of NMDA receptors in neuronal models of an autism spectrum disorder patient with a DSCAM mutation and in Dscam-knockout mice | Heterogeneity in the etiopathology of autism spectrum disorders (ASD) limits the development of generic remedies, requires individualistic and patient-specific research. Recent progress in human-induced pluripotent stem cell (iPSC) technology provides a novel platform for modeling ASDs for studying complex neuronal phenotypes. In this study, we generated telencephalic induced neuronal (iN) cells from iPSCs derived from an ASD patient with a heterozygous point mutation in the DSCAM gene. The mRNA of DSCAM and the density of DSCAM in dendrites were significantly decreased in ASD compared to control iN cells. RNA sequencing analysis revealed that several synaptic function-related genes including NMDA receptor subunits were downregulated in ASD iN cells. Moreover, NMDA receptor (R)-mediated currents were significantly reduced in ASD compared to control iN cells. Normal NMDA-R-mediated current levels were rescued by expressing wild-type DSCAM in ASD iN cells, and reduced currents were observed by truncated DSCAM expression in control iN cells. shRNA-mediated DSCAM knockdown in control iN cells resulted in the downregulation of an NMDA-R subunit, which was rescued by the overexpression of shRNA-resistant DSCAM. Furthermore, DSCAM was co-localized with NMDA-R components in the dendritic spines of iN cells whereas their co-localizations were significantly reduced in ASD iN cells. Levels of phospho-ERK1/2 were significantly lower in ASD iN cells, suggesting a potential mechanism. A neural stem cell-specific Dscam heterozygous knockout mouse model, showing deficits in social interaction and social memory with reduced NMDA-R currents. These data suggest that DSCAM mutation causes pathological symptoms of ASD by dysregulating NMDA-R function. | Lim, Chae-Seok; Kim, Min Jung; Choi, Ja Eun; Islam, Md Ariful; Lee, You-Kyung; Xiong, Yinyi; Shim, Kyu-Won; Yang, Jung-eun; Lee, Ro Un; Lee, Jiah; Park, Pojeong; Kwak, Ji-Hye; Seo, Hyunhyo; Kim, Chul Hoon; Lee, Jae-Hyung; Lee, Yong-Seok; Hwang, Su-Kyeong; Lee, Kyungmin; Lee, Jin-A; Kaang, Bong-Kiun | Seoul Natl Univ, Sch Biol Sci, Seoul 08826, South Korea; Wonkwang Univ, Dept Pharmacol, Sch Med, Jeonbuk 54538, South Korea; Hannam Univ, Dept Biotechnol & Biol Sci, Daejeon 34430, South Korea; Seoul Natl Univ, Interdisciplinary Program Bioinformat, Seoul 08826, South Korea; Kyungpook Natl Univ, Sch Med, Dept Anat, Daegu 41944, South Korea; Yonsei Univ, Dept Pharmacol, Coll Med, Seoul 03722, South Korea; Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Dept Oral Microbiol, Sch Dent, Seoul 02447, South Korea; Seoul Natl Univ, Coll Med, Dept Physiol, Biomed Sci,Neurosci Res Inst, Seoul 03080, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu 41944, South Korea; North South Univ, Sch Hlth & Life Sci, Dept Pharmaceut Sci, Dhaka 1229, Bangladesh | Lee, Jae-Hyung/AAI-9813-2020; park, pojeong/AAT-1716-2021; Kim, Young/T-8521-2019; Choi, Ja Eun/HTR-6298-2023; Kim, Donghee/C-4288-2013; Lee, Caroine Sunyong/AAY-2174-2021; SEO, Hyunhyo/AAR-6343-2021; Islam, Md Ariful/IZE-2734-2023 | 7403654010; 57839629300; 57194772568; 59810378700; 56651292200; 57222749096; 57194762118; 56899164700; 57194777664; 57226124566; 55944871400; 56689173300; 56611228800; 36065422100; 55690041500; 57049728800; 37761570400; 57211016316; 35337365000; 7003889686 | irislkm@knu.ac.kr;leeja@hnu.kr;kaang@snu.ac.kr; | MOLECULAR PSYCHIATRY | MOL PSYCHIATR | 1359-4184 | 1476-5578 | 26 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;NEUROSCIENCES;PSYCHIATRY | 2021 | 13.437 | 4.6 | 1.06 | 2025-07-30 | 19 | 16 | CYCLOSERINE IMPROVES SOCIABILITY; D-ASPARTATE RECEPTORS; SYNAPTIC PLASTICITY; GLUTAMATE RECEPTORS; SPATIAL MEMORY; MOUSE RETINA; DE-NOVO; MECHANISMS; DEFICITS; BEHAVIORS | Animals; Autism Spectrum Disorder; Humans; Mice; Mice, Knockout; Mutation; Neurons; Receptors, N-Methyl-D-Aspartate; messenger RNA; mitogen activated protein kinase 1; mitogen activated protein kinase 3; n methyl dextro aspartic acid receptor; n methyl dextro aspartic acid receptor 1; nestin; short hairpin RNA; n methyl dextro aspartic acid receptor; animal cell; animal experiment; anxiety; Article; autism; Autism Diagnostic Interview Revised; Autism Diagnostic Observation Schedule; case report; child; childhood obesity; clinical article; compulsion; controlled study; crying; dendrite; dendritic spine; down regulation; down syndrome cell adhesion molecule gene; enzyme activity; forebrain; gene; gene expression regulation; gene function; gene knockdown; gene location; gene overexpression; heterozygosity; human; human cell; induced pluripotent stem cell; intellectual impairment; knockout mouse; male; memory disorder; nervous system electrophysiology; neural stem cell; nonhuman; pathophysiology; phenotype; point mutation; protein expression; protein function; protein phosphorylation; RNA sequencing; school child; sleep disorder; social behavior; social interaction; transcriptomics; animal; autism; genetics; metabolism; mouse; mutation; nerve cell | English | 2021 | 2021-12 | 10.1038/s41380-021-01216-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Editorial | Guest Editorial: Learning-Based Edge Computing Services | [No abstract available] | Chen, Min; Wang, Haiyang; Hwang, Kai; Fortino, Giancarlo; Song, Jeungeun; Peng, Limei; Guna, Joze | School of Computer Science and Technology, Huazhong University of Science and Technology (HUST), China; Department of Computer Science, University of Minnesota at Duluth, United States; University of Southern California (USC), United States; Department of Informatics, Modeling, Electronics, and Systems, University of Calabria (Unical), Italy; Department of Electrical and Computer Engineering, University of British Columbia (UBC), Canada; School of Computer Science and Engineering, Kyungpook National University (KNU), Daegu, South Korea; Faculty of Electrical Engineering, University of Ljubljana, Slovenia | 25821032200; 56271044500; 56699307700; 6602895297; 57189515572; 7201574271; 17345882300 | IEEE Network | IEEE NETWORK | 0890-8044 | 1558-156X | 35 | 1 | SCIE | COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2021 | 10.294 | 4.6 | 1 | 2025-07-30 | 1 | English | Final | 2021 | 10.1109/mnet.2021.9355037 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Obesity-linked circular RNA circTshz2-2 regulates the neuronal cell cycle and spatial memory in the brain | Metabolic syndromes, including obesity, cause neuropathophysiological changes in the brain, resulting in cognitive deficits. Only a few studies explored the contribution of non-coding genes in these pathophysiologies. Recently, we identified obesity-linked circular RNAs (circRNA) by analyzing the brain cortices of high-fat-fed obese mice. In this study, we scrutinized a conserved and neuron-specific circRNA, circTshz2-2, which affects neuronal cell cycle and spatial memory in the brain. Transcriptomic and cellular analysis indicated that circTshz2-2 dysregulation altered the expression of cell division-related genes and induced cell cycle arrest at the G2/M phase of the neuron. We found that circTshz2-2 bound to the YY1 transcriptional complex and suppressed Bdnf transcription. Suppression of circTshz2-2 increased BDNF expression and reduced G2/M checkpoint proteins such as Cyclin B2 and CDK1 through BDNF/TrkB signaling pathway, resulting in cell cycle arrest and neurite elongation. Inversely, overexpression of circTshz2-2 decreased BDNF expression, induced cell cycle proteins, and shortened the neurite length, indicating that circTshz2-2 regulates neuronal cell cycle and structure. Finally, we showed that circTshz2-2 affects spatial memory in wild-type and obese mice. Our data have revealed potential regulatory roles of obesity-related circTshz2-2 on the neuronal cell cycle and memory function providing a novel link between metabolic syndromes and cognitive deficits. | Yoon, Gwangho; Lim, Yeong-Hwan; Jo, Danbi; Ryu, Juhee; Song, Juhyun; Kim, Young-Kook | Chonnam Natl Univ, BioMed Sci Grad Program BMSGP, Hwasun 58128, Jeollanam Do, South Korea; Chonnam Natl Univ, Dept Biochem, Med Sch, Hwasun 58128, Jeollanam Do, South Korea; Chonnam Natl Univ, Dept Anat, Med Sch, Hwasun 58128, Jeollanam Do, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu 41566, South Korea | ; Kim, Young-Kook/AAE-8306-2020; Song, Juhyun/AAH-3162-2020 | 57208865908; 57192006927; 57195433652; 57208255566; 55998484600; 57208862490 | juhyunsong@chonnam.ac.kr;ykk@jnu.ac.kr; | MOLECULAR PSYCHIATRY | MOL PSYCHIATR | 1359-4184 | 1476-5578 | 26 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;NEUROSCIENCES;PSYCHIATRY | 2021 | 13.437 | 4.6 | 0.99 | 2025-07-30 | 15 | 15 | EXPRESSION; PROTEIN; GROWTH; PROBDNF; INSULIN; BINDING; CLEAVAGE; NUCLEAR; GLUCOSE; FUSION | Animals; Brain; Brain-Derived Neurotrophic Factor; Cell Cycle Proteins; Cell Division; Mice; Neurons; Obesity; RNA, Circular; Spatial Memory; brain derived neurotrophic factor receptor; circular ribonucleic acid; circular ribonucleic acid Tshz2 2; cyclin B2; cyclin dependent kinase 1; transcription factor YY1; unclassified drug; brain derived neurotrophic factor; cell cycle protein; animal cell; animal experiment; animal model; Article; brain; brain cortex; cell cycle; cell cycle arrest; cell elongation; cell structure; down regulation; G2 phase cell cycle checkpoint; gene expression; gene function; genetic conservation; genetic transcription; mouse; nonhuman; obesity; regulatory mechanism; signal transduction; spatial memory; animal; brain; cell division; genetics; metabolism; nerve cell; obesity | English | 2021 | 2021-11 | 10.1038/s41380-021-01303-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Digital Laser Micropainting for Reprogrammable Optoelectronic Applications | Structural coloration is closely related to the progress of innovative optoelectronic applications, but the absence of direct, on-demand, and rewritable coloration schemes has impeded advances in the relevant area, particularly including the development of customized, reprogrammable optoelectronic devices. To overcome these limitations, a digital laser micropainting technique, based on controlled thin-film interference, is proposed through direct growth of the absorbing metal oxide layer on a metallic reflector in the solution environment via a laser. A continuous-wave laser simultaneously performs two functions-a photothermal reaction for site-selective metal oxide layer growth and in situ real-time monitoring of its thickness-while the reflection spectrum is tuned in a broad visible spectrum according to the laser fluence. The scalability and controllability of the proposed scheme is verified by laser-printed painting, while altering the thickness via supplementary irradiation of the identical laser in the homogeneous and heterogeneous solutions facilitates the modification of the original coloration. Finally, the proof-of-concept bolometer device verifies that specific wavelength-dependent photoresponsivity can be assigned, erased, and reassigned by the successive application of the proposed digital laser micropainting technique, which substantiates its potential to offer a new route for reprogrammable optoelectronic applications. | Lee, Younggeun; Kwon, Jinhyeong; Lim, Jaemook; Shin, Wooseop; Park, Sewoong; Hwang, Eunseung; Shin, Jaeho; Cho, Hyunmin; Jung, Jinwook; Kim, Hyun-Jong; Han, Seungyong; Lee, Habeom; Son, Yong; Ha, Cheol Woo; Prabhakaran, Prem; Yeo, Junyeob; Ko, Seung Hwan; Hong, Sukjoon | Hanyang Univ, Dept Mech Engn, Opt Nanoproc Lab, 55 Hanyangdaehak Ro, Ansan 15588, South Korea; Korea Inst Ind Technol, Intelligent Mfg Syst R&D Dept, 89 Yangdaegiro Gil, Cheonan, Chungcheongnam, South Korea; Seoul Natl Univ, Dept Mech Engn, Appl Nano & Thermal Sci Lab, 1 Gwanak Ro, Seoul 08826, South Korea; Korea Inst Ind Technol, Surface Technol Grp, 156 Gaetbeol Ro, Incheon 21999, South Korea; Pusan Natl Univ, Sch Mech Engn, 2 Busandaehag Ro,63 Beon Gil, Busan 46241, South Korea; Korea Inst Ind Technol, Intelligent Mfg R&D Dept, 113-58 Seohaean Ro, Siheung Si, Gyeonggi Do, South Korea; Hannam Univ, Dept Adv Mat & Chem Engn, 1646 Yuseong Daero, Daejeon, South Korea; Kyungpook Natl Univ, Dept Phys, Novel Appl Nano Opt Lab, 80 Daehak Ro, Daegu 41566, South Korea | Kim, Hyun-Jong/X-3662-2019; Ko, Seung Hwan/B-5448-2008; Ko, Seung Hwan/B-5448-2008; Yeo, Junyeob/I-1287-2013; AHN, IL HYUK/IQU-0381-2023; Prabhakaran, Prem/AAF-4704-2019 | 59859401100; 55780560700; 57203680998; 57194194380; 57191672989; 57216542682; 58732445000; 56784777800; 57193111722; 55744778900; 24337917700; 55356379900; 36104608300; 57833728700; 16317291400; 58692645200; 8699527700; 34973077200 | maxko@snu.ac.kr;sukjoonhong@hanyang.ac.kr; | ADVANCED FUNCTIONAL MATERIALS | ADV FUNCT MATER | 1616-301X | 1616-3028 | 31 | 1 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2021 | 19.924 | 4.7 | 1.02 | 2025-07-30 | 16 | 17 | hydrothermal growth; laser; reprogrammable optoelectronics; structural coloration; thin-film interference | HYDROTHERMAL GROWTH; DEPOSITION; FILMS; NANOPARTICLES; ENHANCEMENT | hydrothermal growth; laser; reprogrammable optoelectronics; structural coloration; thin-film interference | Continuous wave lasers; Metals; Optoelectronic devices; Metal oxide layers; Metallic reflectors; Optoelectronic applications; Photoresponsivity; Photothermal reactions; Real time monitoring; Reflection spectra; Thin-film interference; Metallic compounds | English | 2021 | 2021-01 | 10.1002/adfm.202006854 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effect of non-associated flow rule on fracture prediction of metal sheets using a novel anisotropic ductile fracture criterion | The ductile fracture behavior of anisotropic materials was investigated and modeled by the uncoupled ductile fracture criterion for aluminum alloys 6016-AC200. The ductile fracture model takes into account micromechanisms of void nucleation, void growth, and evolution of void coalescence. The anisotropic yield function and non-associated flow rule were applied to increase the accuracy of the ductile fracture prediction. Series of uniaxial tensile tests, equi-biaxial tension test, and hydraulic bulge test were utilized to identify coefficients of the plasticity model. Various standard fracture tests covering a wide range of stress triaxiality from negative to moderate and high-stress triaxiality were used in order to calibrate the ductile fracture parameters for AA6016-AC200. The strain field on the surface of specimens was captured by the non-contact measurement DIC system for all tests. The fracture surface, fracture locus, and fracture forming limit diagram constructed by the proposed ductile fracture criterion were plotted. These basic fracture tests and a square cup drawing test were simulated by the ABAQUS/Explicit commercial software to verify the efficiency of the proposed fracture criterion and the advanced plastic model in predicting the onset of ductile fracture behavior. The results indicated that the proposed ductile fracture criterion can be utilized for predicting the onset of the anisotropic ductile fracture behavior in sheet metal forming. | Quach, Hung; Kim, Young-Suk | Kyungpook Natl Univ, Grad Sch Mech Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Mech Engn, Daegu 41566, South Korea | Kim, Sang-Hoon/AAA-2248-2020 | 57211711094; 36065820800 | caekim@knu.ac.kr; | INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES | INT J MECH SCI | 0020-7403 | 1879-2162 | 195 | SCIE | ENGINEERING, MECHANICAL;MECHANICS | 2021 | 6.772 | 4.7 | 1.54 | 2025-07-30 | 28 | 27 | Anisotropic ductile fracture; DIC; Non-associated flow rule; Hybrid experimental-numerical method | Anisotropic ductile fracture; DIC; Hybrid experimental-numerical method; Non-associated flow rule | ABAQUS; Aluminum alloys; Anisotropy; Drawing (forming); Forecasting; Fracture mechanics; Fracture testing; Metal forming; Sheet metal; Software testing; Tensile strength; Tensile testing; Anisotropic material; Anisotropic yield functions; Ductile fracture criterion; Fracture forming limit diagrams; Hydraulic bulge test; Non-associated flow rule; Noncontact measurements; Uniaxial tensile test; Ductile fracture | English | 2021 | 2021-04-01 | 10.1016/j.ijmecsci.2020.106224 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Efficient and Stable Perovskite-Based Photocathode for Photoelectrochemical Hydrogen Production | Although organometal halide perovskites (OHPs) have desirable photovoltaic properties, their photoelectrochemical (PEC) water-splitting application for hydrogen production is limited by the instability originating from their intrinsic ionic defects and hygroscopic vulnerability. Herein, a highly efficient and stable OHP-based photocathode achieved by a new zwitterion (L-proline) passivation and a eutectic gallium indium alloy (EGaIn) encapsulation method is described. The zwitterion, which has both cations and anions, can simultaneously passivate both positively and negatively charged defects in OHPs. The resulting OHP photovoltaic cells with passivated shows an over 20% power conversion efficiency with an open-circuit voltage of 1.13 V and a short-circuit current of 22.13 mA cm(-2). The EGaIn-incorporated Ti foil provides complete encapsulation from the external environment while maintaining good transport of photogenerated charges from OHPs. Thus, these photocathodes exhibit a remarkable average photocurrent density of 21.2 mA cm(-2) which has less than 5% current loss between PV cells and PEC cells. More admirably, the photocathode has the highest stability over 54 hours under continuous full sunlight illumination in a sulfuric acid electrolyte. | Kim, Ju-Hyeon; Seo, Sehun; Lee, Jong-Hoon; Choi, Hojoong; Kim, Seungkyu; Piao, Guangxia; Kim, Yong Ryun; Park, Byoungwook; Lee, Jongmin; Jung, Yoonsung; Park, Hyungwoong; Lee, Sanghan; Lee, Kwanghee | Gwangju Inst Sci & Technol, Sch Mat Sci & Engn, Gwangju 61005, South Korea; Gwangju Inst Sci & Technol, Heeger Ctr Adv Mat HCAM, Gwangju 61005, South Korea; Huree Univ Informat & Commun Technol, Dept Energy Resources, Ulaanbaatar 160610036, Mongolia; Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea; Gwangju Inst Sci & Technol, Res Inst Solar & Sustainable Energies RISE, Gwangju 61005, South Korea | Lee, Jaeyoung/AAG-3372-2019; Kim, Yong Ryun/KBC-5758-2024; Lee, Sanghan/AAH-1105-2019; Park, Hyunwoong/A-1247-2012 | 58925648400; 57192688623; 57203144580; 57212019941; 57201488172; 57193277010; 57216573575; 56441933800; 55881826500; 57208525317; 47962513200; 55716521500; 55737466200 | sanghan@gist.ac.kr;klee@gist.ac.kr; | ADVANCED FUNCTIONAL MATERIALS | ADV FUNCT MATER | 1616-301X | 1616-3028 | 31 | 17 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2021 | 19.924 | 4.7 | 4.64 | 2025-07-30 | 54 | 78 | defect engineering; hydrogen evolution; organometal halide perovskites; photocathodes; photoelectrochemical reactions; water splitting; zwitterions | HALIDE PEROVSKITE; SOLAR-CELLS; WATER; STABILITY; PERFORMANCE; INTEGRATION; GALLIUM; LENGTHS; ALLOY | defect engineering; hydrogen evolution; organometal halide perovskites; photocathodes; photoelectrochemical reactions; water splitting; zwitterions | Conversion efficiency; Defects; Electrolytes; Field emission cathodes; Gallium alloys; Indium alloys; Open circuit voltage; Perovskite; Photocathodes; Photocurrents; Photoelectrochemical cells; Photovoltaic cells; Encapsulation methods; External environments; Photocurrent density; Photoelectrochemical hydrogen production; Photoelectrochemicals; Photogenerated charge; Photovoltaic property; Power conversion efficiencies; Hydrogen production | English | 2021 | 2021-04 | 10.1002/adfm.202008277 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Enhanced Thermal Transport across Self-Interfacing van der Waals Contacts in Flexible Thermal Devices | Minimizing the thermal contact resistance (TCR) at the boundary between two bodies in contact is critical in diverse thermal transport devices. Conventional thermal contact methods have several limitations, such as high TCR, low interfacial adhesion, a requirement for high external pressure, and low optical transparency. Here, a self-interfacing flexible thermal device (STD) that can form robust van der Waals mechanical contact and low-resistant thermal contact to planar and non-planar substrates without the need for external pressure or surface modification is presented. The device is based on a distinctive integration of a bioinspired adhesive architecture and a thermal transport layer formed from percolating silver nanowire (AgNW) networks. The proposed device exhibits a strong attachment (maximum 538.9 kPa) to target substrates while facilitating thermal transport across the contact interface with low TCR (0.012 m(2) K kW(-1)) without the use of external pressure, thermal interfacial materials, or surface chemistries. | Seong, Minho; Hwang, Insol; Park, Seongjin; Jang, Hyejin; Choi, Geonjun; Kim, Jaeil; Kim, Shin-Kwan; Kim, Gun-Ho; Yeo, Junyeob; Jeong, Hoon Eui | Ulsan Natl Inst Sci & Technol UNIST, Dept Mech Engn, Ulsan 44919, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | Yeo, Junyeob/I-1287-2013 | 57193896851; 56344839000; 57217113383; 57222134884; 57222136967; 57222527161; 57220044380; 35210569700; 58692645200; 35490647000 | hoonejeong@unist.ac.kr; | ADVANCED FUNCTIONAL MATERIALS | ADV FUNCT MATER | 1616-301X | 1616-3028 | 31 | 48 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2021 | 19.924 | 4.7 | 1.91 | 2025-07-30 | 38 | 37 | bioinspired adhesives; contact formation; flexible transparent heaters; heat flow; thermal contact resistance | CONDUCTIVITY; RESISTANCE; ADHESIVE; TEMPERATURE; PRESSURE; SURFACES; SHAPE | bioinspired adhesives; contact formation; flexible transparent heaters; heat flow; thermal contact resistance | Adhesives; Silver nanowires; Surface chemistry; External pressures; Interfacial adhesions; Mechanical contact; Non-planar substrates; Optical transparency; Thermal contact resistance; Thermal transport; Van der Waals contacts; Van der Waals forces | English | 2021 | 2021-11 | 10.1002/adfm.202107023 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Hybrid State Engineering of Phase-Change Metasurface for All-Optical Cryptography | Chalcogenide material Ge2Sb2Te5(GST) has bistable phases, the so-called amorphous and crystalline phases that exhibit large refractive index contrast. It can be reversibly switched within a nanosecond time scale through applying thermal bias, especially optical or electrical pulse signals. Recently, GST has been exploited as an ingredient of all-optical dynamic metasurfaces, thanks to its ultrafast and efficient switching functionality. However, most of these devices provide only two-level switching functionality and this limitation hinders their application to diverse all-optical systems. In this paper, the method to expand switching functionality of GST metasurfaces to three level through engineering thermo-optically creatable hybrid state that is co-existing state of amorphous and crystalline GST-based meta-atoms is proposed. Furthermore, the novel hologram technique is introduced for providing the visual information that is only recognizable in the hybrid state GST metasurface. Thanks to thermo-optical complexity to make the hybrid state, the metasurface allows the realization of highly secured visual cryptography architecture without the complex optical setup. The phase-change metasurface based on multi-physical design has significant potential for applications such as all-optical image encryption, security, and anti-counterfeiting. | Choi, Chulsoo; Mun, Sang-Eun; Sung, Jangwoon; Choi, Kyunghee; Lee, Seung-Yeol; Lee, Byoungho | Seoul Natl Univ, Interuniv Semicond Res Ctr, Gwanakro 1, Seoul 08826, South Korea; Seoul Natl Univ, Sch Elect & Comp Engn, Gwanakro 1, Seoul 08826, South Korea; Elect & Telecommun Res Inst, Real Devices Res Div, Daejeon 34129, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | ; Lee, Seungwoo/U-8056-2017 | 57194181311; 56779615300; 57193550982; 55722161400; 55881869300; 8114205400 | byoungho@snu.ac.kr; | ADVANCED FUNCTIONAL MATERIALS | ADV FUNCT MATER | 1616-301X | 1616-3028 | 31 | 4 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2021 | 19.924 | 4.7 | 4 | 2025-07-30 | 75 | 72 | Ge2Sb2Te5; holography; metasurface; optical cryptography; phase-change material | ENCRYPTION SCHEME; AMPLITUDE; STORAGE | Ge <sub>2</sub>Sb <sub>2</sub>Te <sub>5</sub>; holography; metasurface; optical cryptography; phase-change material | Antimony compounds; Boolean functions; Chalcogenides; Geometrical optics; Germanium compounds; Nanocrystalline materials; Optical data processing; Refractive index; Switching functions; All-optical systems; Amorphous and crystalline phasis; Anti-counterfeiting; Chalcogenide materials; Co-existing state; Nanosecond time scale; Visual cryptography; Visual information; Cryptography | English | 2021 | 2021-01 | 10.1002/adfm.202007210 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Magnetically Guidable Proteinaceous Adhesive Microbots for Targeted Locoregional Therapeutics Delivery in a Highly Dynamic Environment of Esophagus | The esophagus is a tubular-shaped muscular organ where swallowed fluids and muscular contractions constitute a highly dynamic environment. The turbulent, coordinated processes that occur through the oropharyngeal conduit can often compromise targeted administration of therapeutic drugs to a lesion, significantly reducing therapeutic efficacy. Here, magnetically guidable drug vehicles capable of strongly adhering to target sites using a bioengineered mussel adhesive protein (MAP) to achieve localized delivery of therapeutic drugs against the hydrodynamic physiological conditions are proposed. A suite of highly uniform microparticles embedded with iron oxide (IO) nanoparticles (MAP@IO MPs) is microfluidically fabricated using the genipin-mediated covalent cross-linking of bioengineered MAP. The MAP@IO MPs are successfully targeted to a specific region and prolongedly retained in the tubular-structured passageway. In particular, orally administered MAP@IO MPs are effectively captured in the esophagus in vivo in a magnetically guidable manner. Moreover, doxorubicin (DOX)-loaded MAP@IO MPs exhibit a sustainable DOX release profile, effective anticancer therapeutic activity, and excellent biocompatibility. Thus, the magnetically guidable locomotion and robust underwater adhesive properties of the proteinaceous soft microbots can provide an intelligent modular approach for targeted locoregional therapeutics delivery to a specific lesion site in dynamic fluid-associated tubular organs such as the esophagus. | Choi, Hyun Sun; Jo, Yun Kee; Ahn, Gwang-Noh; Joo, Kye Il; Kim, Dong-Pyo; Cha, Hyung Joon | Pohang Univ Sci & Technol, Dept Chem Engn, 77 Cheongam Ro, Pohang 37673, South Korea; Kyungpook Natl Univ, Dept Biomed Convergence Sci & Technol, Sch Convergence, 80 Daehak Ro, Daegu 41566, South Korea; Ewha Womans Univ, Div Chem Engn & Mat Sci, 52 Ewgayeodae Gil, Seoul 03760, South Korea | Joon, Hyung/AAO-8422-2020 | 57221766849; 56123757800; 57210798725; 21739452800; 56109750200; 55954303800 | hjcha@postech.ac.kr; | ADVANCED FUNCTIONAL MATERIALS | ADV FUNCT MATER | 1616-301X | 1616-3028 | 31 | 46 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2021 | 19.924 | 4.7 | 1.24 | 2025-07-30 | 15 | 25 | adhesive microparticles; esophageal cancer; locoregional drug delivery; magnetic response; oral administration | DRUG-DELIVERY; MUSSEL ADHESION; GENIPIN | adhesive microparticles; esophageal cancer; locoregional drug delivery; magnetic response; oral administration | Adhesives; Biocompatibility; Controlled drug delivery; Iron oxides; Adhesive properties; Covalent crosslinking; Dynamic environments; Muscular contraction; Mussel adhesive proteins; Physiological condition; Therapeutic activity; Therapeutic efficacy; Targeted drug delivery | English | 2021 | 2021-11 | 10.1002/adfm.202104602 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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