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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI ⓘ FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
○ ○ Article ⓘ Functional Characterization of a Novel Oligoalginate Lyase of Stenotrophomonas maltophilia KJ-2 Using Site-Specific Mutation Reveals Bifunctional Mode of Action, Possessing Both Endolytic and Exolytic Degradation Activity Toward Alginate in Seaweed Biomass ⓘ A novel oligoalginate lyase from the marine bacterium, Stenotrophomonas maltophilia KJ-2, completely depolymerizes alginate to monomers with generation of oligomer intermediates. In order to analyze whether KJ-2 oligoalginate lyase has endolytic and exolytic alginate lyase activities, five mutants were developed and characterized using homology modeling based on the crystal structure of Alg17c, an exolytic oligoalginate lyase from Saccharophagus degradans 2-40. The important residues of Tyr238, Arg241, Arg418, and Glu644, which were predicted to be located within hydrogen bonding distance of the non-reducing end of alginate during exolytic catalysis, were mutated to Phe, Ala, Ala, and Ala, respectively. Exolytic activities of Arg241Ala, Glu644Ala, and Arg241AlaGₗᵤ₆₄₄Aₗₐ mutants decreased compared to the wild type, indicating that Arg241 and Glu644 are key residues for exolytic catalysis. Interestingly, these mutants produced oligomers as the main product due to inherent endolytic degradation activity. These mutational characterization results showed that KJ-2 oligoalginate lyase possesses catalytic domains for both inherent endolytic and exolytic activities. ⓘ Chu, Yoo Jung; Kim, Hae Sol; Kim, Myung Sun; Lee, Eun Yeol; Kim, Hee Sook ⓘ Kyungsung Univ, Dept Food Sci & Biotechnol, Busan, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu, South Korea; Kyung Hee Univ, Dept Chem Engn, Gyeonggi Do, South Korea ⓘ Lee, Jae-ung/I-1815-2017; Kim, Cheol-Hee/F-6278-2013 ⓘ 57217166687; 56818181000; 57217170328; 14037776800; 16166551700 ⓘ eunylee@khu.ac.kr; ⓘ FRONTIERS IN MARINE SCIENCE ⓘ FRONT MAR SCI ⓘ 2296-7745 7 SCIE MARINE & FRESHWATER BIOLOGY ⓘ 2020 4.912 5.0 0.55 2025-06-25 ⓘ 9 9 alginate; endolytic activity; exolytic activity; oligoalginate lyase; Stenotrophomonas maltophilia KJ-2 ⓘ MOLECULAR-IDENTIFICATION; CRYSTAL-STRUCTURE; ESCHERICHIA-COLI; DEPOLYMERIZATION; ATU3025; ACID; A1 ⓘ alginate; endolytic activity; exolytic activity; oligoalginate lyase; Stenotrophomonas maltophilia KJ-2 ⓘ ⓘ English 2020 2020-06-03 10.3389/fmars.2020.00420 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Recurrence following hemithyroidectomy in patients with low- and intermediate-risk papillary thyroid carcinoma ⓘ Background This study evaluated the incidence, patterns and risk factors for recurrence after hemithyroidectomy in patients with low- and intermediate-risk papillary thyroid carcinoma (PTC), and verified the predictive role of the risk staging systems in current use. Methods The clinicopathological characteristics and risk categories were analysed according to recurrence in patients who underwent hemithyroidectomy for low- and intermediate-risk conventional PTC, and were followed up for at least 24 months. Five risk staging systems were used to stratify risk: the 2015 American Thyroid Association (ATA) system; Age, Metastases, Extent and Size (AMES) system; Metastases, Age, Complete resection, Invasion and Size (MACIS) system; Grade, Age, Metastases, Extent and Size (GAMES) system; and the eighth AJCC system. Results The study included 561 patients; 93 center dot 9 per cent of the study population (527 of 561) had a papillary thyroid microcarcinoma 1 cm or smaller in size. At a mean follow-up of 83 months, 25 patients (4 center dot 5 per cent) had recurrence; among these patients, 23 (92%) presented with a remaining thyroid lobe. Multifocality was significantly associated with recurrence in univariable and multivariable analyses (adjusted hazard ratio 3 center dot 16, 95 per cent c.i. 1 center dot 25 to 7 center dot 98; P = 0 center dot 015). Disease-free survival (DFS) varied according to multifocality (P = 0 center dot 010). The five risk staging systems were not associated with recurrence, and their Harrell's C-index ranged from 0 center dot 500 to 0 center dot 531. DFS rates did not differ between the risk categories in each system. Conclusion Although the recurrence rate after hemithyroidectomy in patients with low- and intermediate-risk PTC was low, meticulous follow-up focusing on the remaining thyroid lobe is needed for early detection and timely management of recurrence. The risk scoring systems in current use have no predictive role in these patients. ⓘ Ahn, D.; Lee, G. J.; Sohn, J. H. ⓘ Kyungpook Natl Univ, Dept Otolaryngol Head & Neck Surg, 130 Dongdeok Ro, Daegu 41944, South Korea ⓘ ⓘ 44761055400; 57193082568; 55165818100 ⓘ godlikeu@naver.com; ⓘ BRITISH JOURNAL OF SURGERY ⓘ BRIT J SURG ⓘ 0007-1323 1365-2168 107 6 SCIE SURGERY ⓘ 2020 6.939 5.0 2.53 2025-06-25 ⓘ 26 24 ⓘ EXTRATHYROIDAL EXTENSION; MICROCARCINOMA; LOBECTOMY; CANCER; IMPACT ⓘ ⓘ Adolescent; Adult; Aged; Clinical Decision Rules; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Survival Analysis; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroidectomy; Treatment Outcome; Young Adult; thyroglobulin; adult; age; age, metastases, extent and size system; American Thyroid Association; Article; biochemical recurrence; cancer prognosis; cancer recurrence; cancer risk; cancer staging; cancer surgery; cohort analysis; contrast-enhanced ultrasound; disease free survival; female; fine needle aspiration biopsy; follow up; grade, age, metastases, extent and size system; Hashimoto disease; histopathology; human; human tissue; intermediate risk patient; low risk patient; lymph node dissection; lymph node metastasis; lymph vessel metastasis; major clinical study; male; metastases, age, complete resection, invasion and size system; metastasis; middle aged; multifocal disease; needle biopsy; overall survival; positron emission tomography-computed tomography; priority journal; recurrence free survival; retrospective study; risk factor; scoring system; thyroid papillary carcinoma; thyroidectomy; tumor invasion; tumor volume; unifocal disease; adolescent; aged; diagnosis; epidemiology; etiology; incidence; mortality; pathology; predictive value; procedures; risk assessment; survival analysis; thyroid tumor; treatment outcome; tumor recurrence; young adult ⓘ English 2020 2020-05 10.1002/bjs.11430 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Role of tumour location and surgical extent on prognosis in T2 gallbladder cancer: an international multicentre study ⓘ Background In gallbladder cancer, stage T2 is subdivided by tumour location into lesions on the peritoneal side (T2a) or hepatic side (T2b). For tumours on the peritoneal side (T2a), it has been suggested that liver resection may be omitted without compromising the prognosis. However, data to validate this argument are lacking. This study aimed to investigate the prognostic value of tumour location in T2 gallbladder cancer, and to clarify the adequate extent of surgical resection. Methods Clinical data from patients who underwent surgery for gallbladder cancer were collected from 14 hospitals in Korea, Japan, Chile and the USA. Survival and risk factor analyses were conducted. Results Data from 937 patients were available for evaluation. The overall 5-year disease-free survival rate was 70 center dot 6 per cent, 74 center dot 5 per cent for those with T2a and 65 center dot 5 per cent among those with T2b tumours (P = 0 center dot 028). Regarding liver resection, extended cholecystectomy was associated with a better 5-year disease-free survival rate than simple cholecystectomy (73 center dot 0 versus 61 center dot 5 per cent; P = 0 center dot 012). The 5-year disease-free survival rate was marginally better for extended than simple cholecystectomy in both T2a (76 center dot 5 versus 66 center dot 1 per cent; P = 0 center dot 094) and T2b (68 center dot 2 versus 56 center dot 2 per cent; P = 0 center dot 084) disease. Five-year disease-free survival rates were similar for extended cholecystectomies including liver wedge resection versus segment IVb/V segmentectomy (74 center dot 1 versus 71 center dot 5 per cent; P = 0 center dot 720). In multivariable analysis, independent risk factors for recurrence were presence of symptoms (hazard ratio (HR) 1 center dot 52; P = 0 center dot 002), R1 resection (HR 1 center dot 96; P = 0 center dot 004) and N1/N2 status (N1: HR 3 center dot 40, P < 0 center dot 001; N2: HR 9 center dot 56, P < 0 center dot 001). Among recurrences, 70 center dot 8 per cent were metastatic. Conclusion Tumour location was not an independent prognostic factor in T2 gallbladder cancer. Extended cholecystectomy was marginally superior to simple cholecystectomy. A radical operation should include liver resection and adequate node dissection. ⓘ Kwon, W.; Kim, H.; Han, Y.; Hwang, Y. J.; Kim, S. G.; Kwon, H. J.; Vinuela, E.; Jarufe, N.; Roa, J. C.; Han, I. W.; Heo, J. S.; Choi, S-H; Choi, D. W.; Ahn, K. S.; Kang, K. J.; Lee, W.; Jeong, C-Y; Hong, S-C; Troncoso, A. T.; Losada, H. M.; Han, S-S; Park, S-J; Kim, S-W; Yanagimoto, H.; Endo, I; Kubota, K.; Wakai, T.; Ajiki, T.; Adsay, N., V; Jang, J-Y ⓘ Seoul Natl Univ, Dept Surg, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Canc Res Inst, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Surg, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea; Keimyung Univ, Dept Surg, Div Hepatobiliary & Pancreat Surg, Dongsan Med Ctr, Daegu, South Korea; Gyeongsang Natl Univ, Dept Surg, Coll Med, Jinju, South Korea; Natl Canc Ctr, Ctr Liver Canc, Dept Surg, Goyang, South Korea; Catholic Univ Chile, Fac Med, Dept Digest Surg, Santiago, Chile; Catholic Univ Chile, Fac Med, Dept Pathol, Santiago, Chile; Univ La Frontera, Dept Surg, Temuco, Chile; Kansai Med Univ, Dept Surg, Hirakata, Osaka, Japan; Yokohama City Univ, Grad Sch Med, Dept Gastroenterol Surg, Yokohama, Kanagawa, Japan; Dokkyo Med Univ, Dept Gastroenterol Surg, Mibu, Tochigi, Japan; Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata, Japan; Kobe Univ, Dept Surg, Div Hepatobiliary Pancreat Surg, Grad Sch Med, Kobe, Hyogo, Japan; Koc Univ, Dept Pathol, Istanbul, Turkey; Emory Univ, Sch Med, Dept Pathol, Atlanta, GA 30322 USA ⓘ ; Kim, Kyung/I-5501-2015; Kang, Koo/Z-4448-2019; Roa, Juan/K-4749-2014 ⓘ 35211119200; 57103962000; 57206914279; 7402310967; 21735842600; 57199757347; 25639102200; 24740883800; 7003655046; 55263662100; 7102832040; 24477199400; 9245957100; 59712504100; 7402223477; 55705338700; 8933394000; 9633335000; 57202416604; 59842714900; 55740202300; 17233885500; 57745950700; 6603450431; 7103401593; 7402692030; 7004371616; 7005780751; 7003570418; 7402965187 ⓘ jangjy4@snu.ac.kr; ⓘ BRITISH JOURNAL OF SURGERY ⓘ BRIT J SURG ⓘ 0007-1323 1365-2168 107 10 SCIE SURGERY ⓘ 2020 6.939 5.0 6.71 2025-06-25 ⓘ 64 62 ⓘ HEPATIC RESECTION; SURVIVAL; GUIDELINES; CARCINOMA; SURGERY; MANAGEMENT ⓘ ⓘ Adult; Aged; Aged, 80 and over; Chile; Cholecystectomy; Disease-Free Survival; Female; Gallbladder Neoplasms; Hepatectomy; Humans; Japan; Lymph Node Excision; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Republic of Korea; Risk Factors; United States; adult; aged; Article; cancer prognosis; cancer recurrence; cancer risk; cancer staging; cancer surgery; cancer survival; cholecystectomy; computer assisted tomography; disease association; disease free survival; distant metastasis; female; follow up; gallbladder cancer; histology; human; liver resection; lymph node metastasis; major clinical study; male; multicenter study; overall survival; priority journal; recurrence risk; segmentectomy; survival rate; wedge resection; Chile; clinical trial; gallbladder tumor; Japan; lymph node dissection; metastasis; middle aged; mortality; pathology; prognosis; risk factor; South Korea; tumor recurrence; United States; very elderly ⓘ English 2020 2020-09 10.1002/bjs.11618 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Synergistic association of endophytic fungi enhances Glycine max L. resilience to combined abiotic stresses: Heavy metals, high temperature and drought stress ⓘ Recently, the use of endophytic fungi for promoting growth and alleviating abiotic stress has gained considerable attention. However, the association of compatible endophytic fungi with crop plants under simultaneous effects of abiotic stresses is less explored. The current study elucidated the interactive effects of hormone (gibberellins and indole-3-acetic acid)-producing and combined multi-abiotic stresses (heavy metals; Ni, Cd, and Al, drought resistant, high temperature) resistant Paecilomyces formosus LHL10 and Penicillium funiculosum LHLO6 on Glycine max L. under heavy metals (NI, Cd, and Al), high temperature and drought (HID) stress. Results revealed that the co-inoculation of LHL10 and LHLO6 promoted plant growth attributes and photosynthetic activity as well as glutathione, catalase, and SOD activities and decreased lipid peroxidation by enhancing macronutrient uptake under HTD stress. Additionally, the co-inoculation reduced metal accumulation and translocation in plants by down-regulating heavy metal ATPase gene (GmHMA13, GmHMA14, and GmliMA18) expression. Furthermore, the regulation of drought-related GmDREB2, GmDREBIB, GmERD1, GmRD20, and heat shock protein 90 (GmHsp90A2 and GmHsp90A1) gene expression in co-inoculated plants reduced endogenous abscisic acid and jasmonic acid levels and positively affected plant development under HTD stress. The duo of LHL10 and LH1,06 proved to be a vital strategy for the development of G. max in metal-contaminated soil in semiarid and high-temperature conditions for sustainable agriculture. ⓘ Bilal, Saqib; Shahzad, Raheem; Imran, Muhammad; Jan, Rahmatullah; Kim, Kyung Min; Lee, In-Jung ⓘ Kyungpook Natl Univ, Sch Appl Biosci, Daegu, South Korea; Imam Abdulrahman Bin Faisal Univ, Dept Biol, Coll Sci, POB 1982, Dammam 31441, Saudi Arabia; Imam Abdulrahman Bin Faisal Univ, Basic & Appl Sci Res Ctr, POB 1982, Dammam 31441, Saudi Arabia ⓘ ; Lee, In-Jung/GLS-0432-2022; Kim, Kyung-Min Kim/C-7007-2014; Imran, Muhammad/AFL-6590-2022; Jan, Rahmatullah/AIC-3439-2022; Shahzad, Raheem/AAG-8370-2019 ⓘ 57031617400; 56454250900; 58282433800; 57201981969; 34868260300; 16425830900 ⓘ saqib043@yahoo.com;ijlee@knu.ac.kr; ⓘ INDUSTRIAL CROPS AND PRODUCTS ⓘ IND CROP PROD ⓘ 0926-6690 1872-633X 143 SCIE AGRICULTURAL ENGINEERING;AGRONOMY ⓘ 2020 5.645 5.0 11.17 2025-06-25 ⓘ 130 164 Antioxidant; Abscisic acid; Heat shock protein 90; GmDREB; Heay metal ATPase; Soybean ⓘ GROWTH; PLANTS; PHYTOREMEDIATION; TOLERANCE; INOCULATION; BACTERIA; CHLOROPHYLL ⓘ Abscisic acid; Antioxidant; GmDREB; Heat shock protein 90; Heay metal ATPase; Soybean ⓘ Fungi; Glycine max; Penicillium funiculosum; Amino acids; Antioxidants; Crops; Drought; Gene expression; Heavy metals; Proteins; Soil pollution; Abscisic acid; GmDREB; Heat-shock protein 90; Heay metal ATPase; Soybean; abiotic factor; abscisic acid; antioxidant; drought stress; ecosystem resilience; endophyte; fungus; gene expression; heavy metal; high temperature; hormone; inoculation; nutrient uptake; protein; soybean; Fungi ⓘ English 2020 2020-01 10.1016/j.indcrop.2019.111931 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Overexpression of Populus transcription factor PtrTALE12 increases axillary shoot development by regulating WUSCHEL expression ⓘ The TALE (Three Amino acid Loop Extension) transcription factor family has been shown to control meristem formation and organogenesis in plants. To understand the functional roles of the TALE family in woody perennials, each of the TALE members of Populus trichocarpa was overexpressed in Arabidopsis as a proxy. Among them, the overexpression of PtrTALE12 (i.e., 35S::PtrTALE12) resulted in a dramatic increase of axillary shoot development with early flowering. Interestingly, expression of WUSCHEL (WUS), a central regulator of both apical and axillary meristem formation, was significantly increased in the 35S::PtrTALE12 Arabidopsis plants. Conversely, WUS expression was downregulated in 35S::PtrTALE12-SRDX (short transcriptional repressor domain) plants. Further analysis found that PtrTALE12, expressed preferentially in meristem tissues, directly regulates WUS expression in transient activation assays using Arabidopsis leaf protoplast. Yeast two-hybrid assays showed that PtrTALE12 interacts with SHOOT MERISTEMLESS (STM); however, the interaction does not affect the WUS expression. In addition, expression of both CIRCADIAN CLOCK ASSOCIATED1 (CCA 1) and LATE ELONGATED HYPOCOTYL (LHY) genes was suppressed accordingly for early flowering 35S::PtrTALE12 Arabidopsis. Indeed, transgenic poplars overexpressing PtrTALE12 as well as Arabidopsis plants overexpressing AtBLH11, a close homolog of PtrTALE12, phenocopied the 35S::PtrTALE12 Arabidopsis (i.e., increased axillary shoot development). Taken together, our results suggest that PtrTALE12 functions as a positive regulator of axillary shoot formation in both Arabidopsis and poplar. ⓘ Bae, So-Young; Kim, Min-Ha; Cho, Jin-Seong; Park, Eung-Jun; Lee, Hyoshin; Kim, Jeong-Hoe; Ko, Jae-Heung ⓘ Kyung Hee Univ, Dept Plant & Environm New Resources, 1732 Deogyeong Daero, Yongin 17104, South Korea; Natl Inst Forest Sci, Div Forest Biotechnol, 39 Onjeong Ro, Suwon 16631, South Korea; Kyungpook Natl Univ, Sch Biol Sci, Dept Biol, Daegu 41566, South Korea ⓘ Ko, Jae-Heung/A-3370-2013; Kim, So-Young/JFS-7698-2023 ⓘ 57219637218; 57191857381; 56623684600; 7402224154; 8967494800; 7601377826; 7402678816 ⓘ jhko@khu.ac.kr; ⓘ TREE PHYSIOLOGY ⓘ TREE PHYSIOL ⓘ 0829-318X 1758-4469 40 9 SCIE FORESTRY ⓘ 2020 4.196 5.2 0.51 2025-06-25 ⓘ 10 11 axillary shoot development; poplar; PtrTALE12; tree architecture; WUSCHEL ⓘ MERISTEM FORMATION; STRIGOLACTONE BIOSYNTHESIS; GENE-EXPRESSION; APICAL-MERISTEM; FACTOR MYB46; ARABIDOPSIS; PROTEINS; RICE; IDENTIFICATION; REPRESSION ⓘ Axillary shoot development; Poplar; PtrTALE12; Tree architecture; WUSCHEL ⓘ Arabidopsis Proteins; Gene Expression Regulation, Plant; Homeodomain Proteins; Meristem; Populus; Transcription Factors; Arabidopsis; Populus; Populus trichocarpa; Arabidopsis protein; homeodomain protein; transcription factor; activation energy; amino acid; bioassay; biological development; deciduous tree; flowering; gene expression; herb; shoot; gene expression regulation; genetics; meristem; Populus ⓘ English 2020 2020-09 10.1093/treephys/tpaa062 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ The effect of yttrium nitrate addition on the densification behaviour of Y2O3 ceramics during the cold sintering process ⓘ The densification behaviour and phase development of Y2O3 ceramics were investigated as a function of yttrium nitrate (Y(NO3)(3)center dot 6H(2)O) solution addition during the cold sintering process at 200 degrees C. Second phases such as Y4O(OH)(9)NO3 and Y(OH)(3) were observed after the cold sintering process. The amount of Y4O(OH)(9)NO3 increased with increasing amount of yttrium nitrate, while the amount of Y(OH)(3) decreased. The second phases were transformed to fine sized Y2O3 (similar to 30 nm) particles smaller than those of the raw powder ( < 400 mu m) by sintering at 600 degrees C. The fine sized Y2O3 particles were located in the voids between the larger Y2O3 particles, thus increasing the packing density and enhancing the densification of the Y2O3 ceramics after the final sintering process. ⓘ Lee, Doyun; Lee, Jung-A; Heo, Young-Woo; Lee, Joon-Hyung; Jung, Jae-Il; Kim, Jeong-Joo ⓘ Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Chosun Refractories Co Ltd, Res Grp, Pohang 37862, Gyeongsangbuk D, South Korea ⓘ Lee, Jung/AAP-7829-2021; Kim, Jihyun/F-6940-2013 ⓘ 57208088190; 55108410500; 7004298542; 57204923460; 57199984365; 8214705700 ⓘ jjkim@knu.ac.kr; ⓘ JOURNAL OF THE EUROPEAN CERAMIC SOCIETY ⓘ J EUR CERAM SOC ⓘ 0955-2219 1873-619X 40 8 SCIE MATERIALS SCIENCE, CERAMICS ⓘ 2020 5.302 5.2 0.21 2025-06-25 ⓘ 12 11 Y2O3; Cold sintering process; Low-temperature sintering; Densification ⓘ TRANSPARENT Y2O3; GRAIN-GROWTH; POWDER ⓘ Cold sintering process; Densification; Low-temperature sintering; Y<sub>2</sub>O<sub>3</sub> ⓘ Densification; Nitrates; Temperature; Cold sintering; Densification behaviour; Low-temperature sintering; Packing density; Phase development; Raw powders; Sintering process; Y2O3; Sintering ⓘ English 2020 2020-07 10.1016/j.jeurceramsoc.2020.02.025 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ The effects of indoor ambient temperature at work on physiological adaptation in night shift nurses ⓘ Aim To examine the effects of indoor ambient temperature on thermal comfort, night work tolerance (fatigue, sleepiness and night adaptation) and urinary melatonin in night shift nurses. Background Night shift induces physical stress and mental stress. Night shift work and ambient temperature are associated with work performance. The working environment must be improved for successful night shift working. However, the effects of indoor ambient temperature on night shift nurses are unclear. Methods In this crossover study, 20 participants were divided into two groups of 10 and were assigned to work in one of two thermo-controlled environments (23 degrees C vs. 26 degrees C) during two consecutive night shifts. Thermal and humidity sensation vote, night work tolerance, body temperature and urinary melatonin were assessed. Results There were significant differences between the two groups in thermal sensation and body temperature. There were no significant differences in humidity sensation vote or night work tolerance. Urinary melatonin levels decreased significantly during the second 23 degrees C night shift. Conclusion A temperature of 23 degrees C may exert a positive effect on night shift adaptation. Implications for Nursing Management Nurses and nursing managers should assess thermal comfort during night shifts, and improved thermal comfort level should be provided to nurses. ⓘ Kim, Jeong Hun; Song, Yeoungsuk ⓘ Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Kyungpook Natl Univ, Res Inst Nursing Sci, Coll Nursing, Daegu, South Korea ⓘ Kim, Jeong Hun/ABB-5596-2021; Song, Yeoungsuk/MSZ-3096-2025 ⓘ 57233549000; 55494171100 ⓘ asansong@knu.ac.kr; ⓘ JOURNAL OF NURSING MANAGEMENT ⓘ J NURS MANAGE ⓘ 0966-0429 1365-2834 28 5 SSCI;SCIE MANAGEMENT;NURSING ⓘ 2020 3.325 5.2 0.12 2025-06-25 ⓘ 1 1 6-sulphatoxymelatonin; nurses; temperature; work performance ⓘ CIRCADIAN-RHYTHMS; THERMAL COMFORT; CORTISOL; LIGHT ⓘ 6-sulphatoxymelatonin; nurses; temperature; work performance ⓘ Adaptation, Physiological; Adult; Chi-Square Distribution; Cross-Over Studies; Female; Humans; Male; Nurses; Shift Work Schedule; Surveys and Questionnaires; Temperature; adaptation; adult; adverse event; chi square distribution; controlled study; crossover procedure; female; human; male; nurse; psychology; questionnaire; randomized controlled trial; shift schedule; temperature ⓘ English 2020 2020-07 10.1111/jonm.13052 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Altered gut microbiota by azithromycin attenuates airway inflammation in allergic asthma ⓘ ⓘ Park, Han-Ki; Choi, Youngwoo; Lee, Dong-Hyun; Kim, Sujeong; Lee, Jong-Myung; Choi, Sae Won; Lee, Hee-Ra; Rho, Mina; Park, Hae-Sim ⓘ Kyungpook Natl Univ, Sch Med, Dept Allergy & Clin Immunol, Daegu, South Korea; Ajou Univ, Sch Med, Dept Allergy & Clin Immunol, Suwon, South Korea; Seoul Natl Univ Hosp, Off Hosp Informat, Seoul, South Korea; MD Healthcare Inc, Seoul, South Korea; Hanyang Univ, Dept Comp Sci & Engn, Seoul, South Korea ⓘ Kim, Ju-Hyoung/N-1450-2019; Park, Han-Ki/AAY-3102-2020; xu, jingcheng/HJZ-3124-2023; Lee, Heera/GWQ-5858-2022 ⓘ 57218664064; 57195469608; 57195772614; 36666447400; 36123106800; 56124321400; 57211691912; 16302227400; 57192203361 ⓘ hspark@ajou.ac.kr; ⓘ JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY ⓘ J ALLERGY CLIN IMMUN ⓘ 0091-6749 1097-6825 145 5 SCIE ALLERGY;IMMUNOLOGY ⓘ 2020 10.793 5.4 0.9 2025-06-25 ⓘ 27 30 ⓘ ANTIBIOTICS; LIFE ⓘ ⓘ Allergens; Animals; Anti-Bacterial Agents; Asthma; Azithromycin; Bronchoalveolar Lavage Fluid; Cefixime; Cytokines; Fecal Microbiota Transplantation; Feces; Female; Gastrointestinal Microbiome; Mice, Inbred BALB C; Ovalbumin; Th2 Cells; acetic acid; azithromycin; bacterial DNA; butyric acid; cefixime; gamma interferon; interleukin 10; interleukin 13; interleukin 4; interleukin 5; isobutyric acid; ovalbumin; propionic acid; RNA 16S; allergen; antiinfective agent; azithromycin; cefixime; cytokine; allergic airway inflammation; allergic asthma; animal cell; animal experiment; animal model; animal tissue; antibiotic therapy; Article; bacterial load; Bacteroidaceae; bronchoalveolar lavage fluid; Clostridiales; Clostridium; commensal; controlled study; cytokine release; drug efficacy; dysbiosis; fecal microbiota transplantation; female; histopathology; host bacterium interaction; inflammation; intestine flora; Lachnospiraceae; microbial diversity; mouse; nonhuman; priority journal; respiratory tract allergy; Ruminococcaceae; species composition; T lymphocyte; Th2 cell; animal; asthma; Bagg albino mouse; cytology; drug effect; feces; immunology; intestine flora; microbiology ⓘ English 2020 2020-05 10.1016/j.jaci.2020.01.044 ⓘ 바로가기 바로가기 바로가기 바로가기
○ Meeting Abstract ⓘ Application of exhaled breath condensate cytokines to sort asthma phenotypes ⓘ ⓘ Kim, Min-Hye; Shim, Ji-Su; Kim, Byung-Keun; Park, Han-Ki; Yang, Min-Suk; Kwon, Jae-Woo; Cho, Young Joo ⓘ Ewha Womans Univ, Coll Med, Seoul, South Korea; Korea Univ, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Daegu, South Korea; SMG SNU Boramae Med Ctr, Seoul, South Korea; Kangwon Natl Univ, Sch Medicine, Chunchon, South Korea ⓘ Kim, Byung-Keun/N-4256-2018; Park, Han-Ki/AAY-3102-2020 ⓘ ⓘ ⓘ JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY ⓘ J ALLERGY CLIN IMMUN ⓘ 0091-6749 1097-6825 145 2 SCIE ALLERGY;IMMUNOLOGY ⓘ 2020 10.793 5.4 ⓘ 0 ⓘ ⓘ ⓘ ⓘ English 2020 2020-02 ⓘ 바로가기 바로가기
○ ○ Article ⓘ Control of silver nanowire-elastomer nanocomposite networks through elaborate direct printing for ultrathin and stretchable strain sensors ⓘ Control of film's properties is the most important for providing of customized electronic devices. In particular, when the nanocomposite networks are applied to the films for needs of various applications, the quality of film is considered as one of the most potent factors. Here, we propose a viable and facile method of controlling the silver nanowire (Ag NW)-elastomer nanocomposite networks through elaborate direct printing for implementing sandwich-structured ultrathin and stretchable strain sensors. According to the different Ag NW network densities controlled by various blade coating parameters, surface morphological characteristics, optical transmittance, and current-voltage performance were investigated. In order to exhibit the importance of network density control to electronic devices, we fabricated two stretchable strain sensors with different sensitivities (Delta R/R-0: 6.31, 0.70 at 10% strain) using low density (LD) and high density (HD) Ag NWs networks for detecting small and large movements, respectively. Under repeated stretching fatigue tests (1000 cycles), LD and HD Ag NW sensors show stable sensing operation with electromechanical durability and frequency-responsive features. A simple application for wrist motion detection with a fast response speed and stable operation is demonstrated. These results provide a new route towards next-generation skin electronics. ⓘ Park, Jun-Ik; Kim, Do-Kyung; Jang, Jaewon; Kang, In Man; Kim, Hyeok; Park, Jaehoon; Nam, Il Woo; Lang, Philippe; Bae, Jin-Hyuk ⓘ Kyungpook Natl Univ, Sch Elect Engn, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehakro, Daegu 41566, South Korea; Univ Seoul, Sch Elect & Comp Engn, 163 Seoulsiripdaero, Seoul 02504, South Korea; Univ Seoul, Inst Informat Technol, 163 Seoulsiripdaero, Seoul 02504, South Korea; Hallym Univ, Dept Elect Engn, 1 Hallimdaehak Gil, Chunchon 24252, South Korea; Handong Global Univ, Sch Spatial Environm Syst Engn, 558 Handong Ro, Pohang 37554, Gyeongbuk, South Korea; Univ Paris, ITODYS, CNRS, UMR 7086, 15 Rue Jean Antoine de Baif, F-75205 Paris 13, France ⓘ lang, philippe/E-5192-2012; Nam, Ilwoo/AAJ-3862-2020 ⓘ 57210189987; 57984042900; 57194107504; 7203062678; 57191718658; 55717156300; 43761351000; 36181262200; 35326180700 ⓘ jhbae@ee.knu.ac.kr; ⓘ COMPOSITES SCIENCE AND TECHNOLOGY ⓘ COMPOS SCI TECHNOL ⓘ 0266-3538 1879-1050 200 SCIE MATERIALS SCIENCE, COMPOSITES ⓘ 2020 8.528 5.4 0.93 2025-06-25 ⓘ 13 15 Nanocomposite; Network density; Direct printing; Stretchable strain sensor; Human motion detection ⓘ RAPID-RESPONSE; TRANSPARENT; COMPOSITES; SKIN; ELECTRONICS ⓘ Direct printing; Human motion detection; Nanocomposite; Network density; Stretchable strain sensor ⓘ Durability; Elastomers; Electric resistance measurement; Electronic equipment; Fatigue testing; Nanocomposite films; Nanocomposites; Silver nanowires; Thermoelectric equipment; Blade coatings; Direct printing; Electronic device; Morphological characteristic; Network density; Network density control; Stable operation; Strain sensors; Silver ⓘ English 2020 2020-11-10 10.1016/j.compscitech.2020.108471 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Enhanced electrical conductivity of polymer nanocomposite based on edge-selectively functionalized graphene nanoplatelets ⓘ Achieving high filler dispersion in a polymer composite is very important for effectively and efficiently imparting several advantages of functional fillers to the composite. To this end, we have suggested a synthesis of polyamide 6 via in situ ring-opening polymerization of epsilon-caprolactam and edge-selectively functionalized graphene nanoplatelets without defects on its basal plane synthesized by a ball-mill process with dry ice. As a consequence, the final graphene nanocomposite possesses highly dispersed filler and has enhanced electrical conductivity due to its undistorted sp(2) hybridization after functionalization. This approach is a promising way of incorporating filler into polymer composites, effectively implementing highly electrical conducting graphene without its aggregation and damage to its inherent properties after functionalization. ⓘ Cho, Jaehyun; Lee, Hyeseong; Nam, Ki-Ho; Yeo, Hyeonuk; Yang, Cheol-Min; Seong, Dong Gi; Lee, Doojin; Kim, Seong Yun ⓘ KIST, Inst Adv Composite Mat, 92 Chudong Ro, Wanju Gun 55324, Jeonbuk, South Korea; Chonbuk Natl Univ, Div Polymer Nano & Text Engn, 567 Baekje Daero, Jeonju 54896, South Korea; Kyungpook Natl Univ, Dept Chem Educ, Chem Bldg,80 Daehak Ro, Daegu 41566, South Korea; Pusan Natl Univ, Dept Polymer Sci & Engn, Busan 46241, South Korea; Chonnam Natl Univ, Dept Polymer Sci & Engn, Gwangju 61186, South Korea ⓘ Seong, Dong/AAI-4323-2020; yeo, hyeonuk/G-7890-2017; Yeo, Hyeonuk/AHE-0397-2022; Ku, Bon-Cheol/I-7493-2019 ⓘ 57195224674; 57192501614; 55553181500; 55324816500; 57207279430; 13305625300; 7406664766; 55718774000 ⓘ dlee@chonnam.ac.kr;sykim82@jbnu.ac.kr; ⓘ COMPOSITES SCIENCE AND TECHNOLOGY ⓘ COMPOS SCI TECHNOL ⓘ 0266-3538 1879-1050 189 SCIE MATERIALS SCIENCE, COMPOSITES ⓘ 2020 8.528 5.4 2.7 2025-06-25 ⓘ 44 47 Particle-reinforced composites; Polymer-matrix composites (PMCs); Nano composites; Electrical properties; Modelling ⓘ EFFECTIVE THERMAL-CONDUCTIVITY; NONCOVALENT FUNCTIONALIZATION; GAS BARRIER; COMPOSITES; OXIDE; FACILE ⓘ Electrical properties; Modelling; Nano composites; Particle-reinforced composites; Polymer-matrix composites (PMCs) ⓘ Carbon dioxide; Electric conductance; Electric conductivity of solids; Electric properties; Filled polymers; Fillers; Graphene; Models; Nanocomposites; Particle reinforced composites; Ring opening polymerization; Electrical conductivity; Functional fillers; Functionalizations; Functionalized graphene; Graphene nanocomposites; Polymer composite; Polymer Matrix Composites (PMCs); Polymer nanocomposite; Polymer matrix composites ⓘ English 2020 2020-03-22 10.1016/j.compscitech.2020.108001 ⓘ 바로가기 바로가기 바로가기 바로가기
○ Meeting Abstract ⓘ The effect and safety of rapid aspirin desensitization in Korean patients ⓘ ⓘ Kim, Byung-Keun; Park, Han-Ki; Kim, Min-Hye; Kwon, Jae-Woo; Yang, Min-Suk; Kim, Sae-Hoon; Chang, Yoon-Seok ⓘ Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Ewha Womans Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Kangwon Natl Univ, Sch Med, Dept Internal Med, Chunchon, South Korea; SMG SNU Boramae Med Ctr, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea ⓘ Park, Han-Ki/AAY-3102-2020; Chang, Yoon-Seok/J-5628-2012; Kim, Byung-Keun/N-4256-2018 ⓘ ⓘ ⓘ JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY ⓘ J ALLERGY CLIN IMMUN ⓘ 0091-6749 1097-6825 145 2 SCIE ALLERGY;IMMUNOLOGY ⓘ 2020 10.793 5.4 ⓘ 0 ⓘ ⓘ ⓘ ⓘ English 2020 2020-02 ⓘ 바로가기 바로가기
○ ○ Article ⓘ Bone-Graft Resorption Reduced by the Induced Membrane Technique and Factors Affecting Volumetric Changes: An Analysis of 120 Serial Computed Tomographic Scans in 40 Patients ⓘ Background:Little is known about the volumetric changes of grafted bone over time when using the induced membrane technique. This study investigates the volumetric changes of bone graft using serial computed tomographic (CT) scans following the induced membrane technique.Methods:Patients with critical-sized bone defects had serial CT scans after undergoing bone-grafting using the induced membrane technique. CT scans to evaluate the volume of bone graft were obtained immediately postoperatively and at 6 and 12 months. The change in the volume of bone graft was determined at 6 and 12 months postoperatively. Patient demographic characteristics, the location and composition of the bone graft, and the type of fixation construct were analyzed.Results:Forty patients met inclusion criteria. There were 27 tibiae and 13 femora with a mean size defect of 8.6 cm (range, 2.5 to 20.6 cm). Of these patients, 21 received autograft with cancellous bone graft and 19 received mixed autogenous bone with demineralized bone matrix (DBM) at a mean time of 17 weeks after the membrane formation. For the first 6 months, there was an overall osseous resorption of -9.9%. The overall graft volume from 6 to 12 months demonstrated an increase of osseous volume by +1.6%. For the entire 12-month period, there was a mean graft volume resorption of -8.3%. A correlation was found between the early volumetric changes of grafted bone and the percentage of DBM in the graft mixture. A correlation was also found between the late volumetric changes and the location of defect or the type of fixation.Conclusions:At 1 year after use of the induced membrane technique for the treatment of a critical-sized bone defect, resorption of the grafted bone averaged -8.3%. The volumetric changes were influenced by the property of the grafted bone, the fixation construct, and the location of the defect.Level of Evidence:Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. ⓘ Cho, Jae-Woo; Kent, William T.; Oh, Chang-Wug; Kim, Beom-Soo; Cho, Won-Tae; Oh, Jong-Keon ⓘ Korea Univ, Guro Hosp, Coll Med, Dept Orthoped Surg, Seoul, South Korea; Univ Calif San Diego, Dept Orthoped Surg, San Diego, CA 92103 USA; Kyungpook Natl Univ, Dept Orthoped Surg, Kyungpook Natl Univ Hosp, Sch Med, Daegu, South Korea; Keimyung Univ, Dept Orthoped Surg, Dongsan Med Ctr, Sch Med, Daegu, South Korea; Ajou Univ, Dept Orthoped Surg, Sch Med, Suwon, South Korea ⓘ Oh, Chang-Wug/AAO-4602-2021 ⓘ 34969104500; 57192948988; 22135834200; 57161242900; 56197181800; 7402155046 ⓘ ccarius85@gmail.com;jk.oh@korea.ac.kr; ⓘ JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME ⓘ J BONE JOINT SURG AM ⓘ 0021-9355 1535-1386 102 14 SCIE ORTHOPEDICS;SURGERY ⓘ 2020 5.284 5.5 0.95 2025-06-25 ⓘ 13 14 ⓘ MASQUELET TECHNIQUE; BARRIER MEMBRANES; DEFECTS; RECONSTRUCTION; MANAGEMENT; TRANSPORT; REPAIR; AUTOGRAFTS; PERIOSTEUM ⓘ ⓘ Adult; Aged; Aged, 80 and over; Bone Plates; Bone Resorption; Bone Transplantation; Female; Fibula; Humans; Male; Middle Aged; Tibia; Tomography, X-Ray Computed; Young Adult; adult; aged; Article; bone defect; bone graft; bone matrix; bone volume; clinical article; cohort analysis; computer assisted tomography; demography; female; fracture fixation; human; human tissue; induced membrane technique; male; orthopedic surgery; osteolysis; postoperative period; priority journal; bone plate; bone transplantation; diagnostic imaging; fibula; middle aged; osteolysis; procedures; surgery; tibia; very elderly; x-ray computed tomography; young adult ⓘ English 2020 2020-07-15 10.2106/jbjs.19.00804 ⓘ 바로가기 바로가기 바로가기 바로가기
○ ○ Article ⓘ Excessive groundwater inflow during TBM tunneling in limestone formation ⓘ A sudden increase of groundwater inflow of 670 tons a day was experienced during tunneling in a limestone formation at around 53 m below the ground surface. The limestone cavities were expected to be located at 5-10 m or more above the tunnel crown in geotechnical exploration. However, limestone cavity network was encountered at the tunnel depth, and large groundwater inflow was experienced. Because of the excessive groundwater inflow into the tunnel, the groundwater level dropped to GL-32 m from the original level of GL-16 m, and consequently maximum of 23 mm of ground settlement and damage of adjacent structures took place. In this study the change of groundwater regime during tunneling in limestone area containing cavity network was analyzed through 3-dimensional numerical analysis, and the mechanism of groundwater level drawdown followed by ground subsidence was analyzed by comparing measurements and numerical analysis results. And also the analytical solution for determining the range of cutoff grouting was proposed to minimize groundwater inflow during excavation in a fractured zone. ⓘ Lee, Sungjune; Moon, Joon-Shik ⓘ Cheongju Univ, Div Human Environm Design, Dept Civil Engn, Cheongju 28503, South Korea; Kyungpook Natl Univ, Dept Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea ⓘ ⓘ 44361189200; 57149572000 ⓘ j.moon@knu.ac.kr; ⓘ TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY ⓘ TUNN UNDERGR SP TECH ⓘ 0886-7798 96 SCIE CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, CIVIL ⓘ 2020 5.915 5.5 0.46 2025-06-25 ⓘ 12 12 Groundwater inflow; Ground subsidence; Limestone; Cavity; EPBM; 3-D numerical analysis; Back-analysis ⓘ CONSTRUCTION; EXCAVATION ⓘ 3-D numerical analysis; Back-analysis; Cavity; EPBM; Ground subsidence; Groundwater inflow; Limestone ⓘ Lime; Limestone; Numerical analysis; Subsidence; Tunneling (excavation); 3-D numerical analysis; Back analysis; Cavity; EPBM; Ground water inflow; back analysis; cavity; groundwater flow; limestone; numerical method; subsidence; TBM; tunneling; Groundwater ⓘ English 2020 2020-02 10.1016/j.tust.2019.103217 ⓘ 바로가기 바로가기 바로가기 바로가기
○ Meeting Abstract ⓘ Neuroinflammation Genomic Markers in Genome-wide Association Study of Parkinson's Disease ⓘ ⓘ Chung, Sun J.; Choi, Nari; Kim, Juyeon; Kim, Kiju; Kim, Mi-Jung; Kim, Young Jin; Ryu, Ho-Sung; Park, Kye Won ⓘ Asan Med Ctr, Neurol, Seoul, South Korea; Metro Hosp, Neurol, Noida, India; Good Light Hosp, Seoul, South Korea; Bobath Mem Hosp, Neurol, Seongnam, South Korea; Best Heals Hosp, Neurol, Seoul, South Korea; Kyungpook Natl Univ Hosp, Neurol, Daegu, South Korea ⓘ ⓘ ⓘ ⓘ NEUROLOGY ⓘ NEUROLOGY ⓘ 0028-3878 1526-632X 94 15 SCIE CLINICAL NEUROLOGY ⓘ 2020 9.91 5.5 ⓘ 0 ⓘ ⓘ ⓘ ⓘ English 2020 2020-04-14 ⓘ 바로가기 바로가기
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