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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Fluoropolymer-based organic memristor with multifunctionality for flexible neural network system In this study, we propose an effective strategy for achieving the flexible one organic transistor-one organic memristor (1T-1R) synapse using the multifunctional organic memristor. The dynamics of the conductive nanofilament (CF) in a hydrophobic fluoropolymer medium is explored and a hydrophobic fluoropolymer-based organic memristor is developed. The flexible 1T-1R synapse can be fabricated using the solution process because the hydrophobic fluorinated polymer layer is produced on the organic transistor without degradation of the underlying semiconductor. The developed flexible synapse exhibits multilevel conductance with high reliability and stability because of the fluoropolymer film, which acts as a medium for CF growth and an encapsulating layer for the organic transistor. Moreover, the synapse cell shows potential for high-density memory systems and practical neural networks. This effective concept for developing practical flexible neural networks would be a basic platform to realize the smart wearable electronics. Kim, Min-Hwi; Park, Hea-Lim; Kim, Min-Hoi; Jang, Jaewon; Bae, Jin-Hyuk; Kang, In Man; Lee, Sin-Hyung Seoul Natl Univ, Sch Elect & Comp Engn, 1 Gwanak Ro, Seoul 08826, South Korea; Seoul Natl Univ Sci & Technol, Dept Mat Sci & Engn, Seoul 01811, South Korea; Hanbat Natl Univ, Dept Creat Convergence Engn, Daejeon 305719, South Korea; Kyungpook Natl Univ, Sch Elect Engn, 80 Daehak Ro, Daegu 702701, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehak Ro, Daegu 702701, South Korea Lee, Sin-Hyung/ABD-6425-2022 56647038300; 55735654600; 38260922200; 57194107504; 35326180700; 7203062678; 57226880204 sinhlee@knu.ac.kr; NPJ FLEXIBLE ELECTRONICS NPJ FLEX ELECTRON 2397-4621 5 1 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;MATERIALS SCIENCE, MULTIDISCIPLINARY 2021 12.019 3.8 3.12 2025-07-30 66 65 RESISTIVE SWITCHING CHARACTERISTICS; ARTIFICIAL SYNAPSE; CONDUCTIVE FILAMENT; MEMORY; GROWTH; DEVICE; TRANSISTOR; INTERFACE English 2021 2021-12-17 10.1038/s41528-021-00132-w 바로가기 바로가기 바로가기 바로가기
Article Generation of cd63-deficient zebrafish to analyze the role of cd63 in viral infection The tetraspanin superfamily proteins are transmembrane proteins identified in a diverse range of eukaryotic organisms. Tetraspanins are involved in a variety of essential biological functions, including cell differentiation, adhesion, migration, signal transduction, intracellular trafficking, and immune responses. For an infection to occur, viruses must interact with various cell surface components, including receptors and signaling molecules. Tetraspanin CD63 is involved in the organization of the cell membrane and trafficking of cellular transmembrane proteins that interact with many viruses. In this study, the cd63 gene was characterized by studying its expression and function in a zebrafish model. The functional domains and structural features of Cd63, such as the Cys-CysGly (CCG) motif in the large extracellular loop and cysteine residues, are conserved in zebrafish. We confirmed that cd63 was expressed in immune system organs, such as the axial vein and pronephric duct, during the embryonic development of zebrafish. To better understand the role of cd63 in the zebrafish immune system, we established cd63-deficient zebrafish lines using the clustered regularly interspaced short palindromic repeats/ CRISPR-associated protein 9 (CRISPR/Cas9) system. A 19 bp insertion mutation was generated in single guide RNA (sgRNA) target sequence of exon 3 of the cd63 gene, to create a pre-mature stop codon. We then analyzed the expression of cd63-related genes cxcr4a and cxcr4b in wild type (WT) and cd63-deficient zebrafish. We believe our study provides an important model that could be used to investigate the roles of cd63 in viral infection in vivo. Jung, Sumi; Kim, Myoung-Jin; Sellaththurai, Sarithaa; Kim, Suna; Lee, Seongdo; Lee, Jehee Jeju Natl Univ, Dept Marine Life Sci, Jeju 63243, Jeju Self Gover, South Korea; Jeju Natl Univ, Fish Vaccine Res Ctr, Jeju 63243, Jeju Self Gover, South Korea; Jeju Natl Univ, Marine Sci Inst, Jeju 63333, Jeju Self Gover, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Natl Fishery Prod Qual Management Serv, Gen Affairs Div, Busan 49111, South Korea Lee, Jehee/AAS-3229-2021 57200687597; 57191626729; 57208274565; 57221945326; 56034024400; 7601467203 jehee@jejunu.ac.kr; FISH & SHELLFISH IMMUNOLOGY FISH SHELLFISH IMMUN 1050-4648 1095-9947 111 SCIE FISHERIES;IMMUNOLOGY;MARINE & FRESHWATER BIOLOGY;VETERINARY SCIENCES 2021 4.622 3.8 0.51 2025-07-30 6 5 Zebrafish; cd63 knockout; CRISPR; Cas9 system; Immune response; Viral infection cd63 knockout; CRISPR/Cas9 system; Immune response; Viral infection; Zebrafish Amino Acid Sequence; Animals; Fish Diseases; Fish Proteins; Gene Expression Profiling; Gene Expression Regulation; Immunity; Novirhabdovirus; Phylogeny; Rhabdoviridae Infections; Sequence Alignment; Tetraspanin 30; Zebrafish; CD63 antigen; chemokine receptor CXCR4; CRISPR associated endonuclease Cas9; guide RNA; tetraspanin; CD63 antigen; fish protein; adult; animal experiment; animal model; Article; cell adhesion; cell differentiation; cell migration; channel catfish; comparative study; controlled study; CRISPR-CAS9 system; Cygnus atratus; exon; immune response; immune system; mRNA expression level; Mus musculus; nonhuman; osmotic pressure; Paralichthys olivaceus; priority journal; RNA isolation; signal transduction; stop codon; virus infection; zebra fish; amino acid sequence; animal; chemistry; fish disease; gene expression profiling; gene expression regulation; genetics; immunity; immunology; Novirhabdovirus; phylogeny; physiology; rhabdovirus infection; sequence alignment; veterinary medicine; zebra fish English 2021 2021-04 10.1016/j.fsi.2021.01.016 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Quantitative Computed Tomography Imaging Metric Based Assessment of Airway Structural and Lung Functional Alterations During Asthma Acute Exacerbations Park, J.; Kim, S.; Lim, J.; Jin, K.; Yang, M.; Chae, K.; Jin, G.; Kim, T.; Kim, H.; Lee, C.; Lee, K.; Choi, S. Kyungpook Natl Univ, Sch Mech Engn, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Div Allergy & Clin Immunol, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Seoul Natl Univ, Boramae Med Ctr, Seoul Metropolitan Govt, Dept Radiol, Seoul, South Korea; Seoul Natl Univ, Boramae Med Ctr, Seoul Metropolitan Govt, Dept Internal Med, Seoul, South Korea; Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Biomed Res Inst, Dept Radiol,Res Inst Clin Med, Jeonju, South Korea; Asan Med Ctr, Dept Allergy & Clin Immunol, Seoul, South Korea; Kosin Univ, Gospel Hosp, Coll Med, Dept Internal Med, Busan, South Korea; Seoul Nat Univ Hosp, Coll Med, Dept Radiol, Seoul, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Stat, Daegu, South Korea skswkr@naver.com; AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE AM J RESP CRIT CARE 1073-449X 1535-4970 203 9 SCIE CRITICAL CARE MEDICINE;RESPIRATORY SYSTEM 2021 30.528 3.8 0 English 2021 2021-05-01 바로가기 바로가기
Article Short-wave infrared organic phototransistors with strong infrared-absorbing polytriarylamine by electron-transfer doping Short-wavelength infrared (SWIR) sensors have attracted keen attention due to the increasing necessity in a variety of scientific and industrial applications, including biomedical and information technology fields. Because conventional SWIR sensors are made of inorganic materials with rigid and brittle characteristics, organic materials with a discrete SWIR absorption are required for flexible SWIR sensors in the flexible electronics era. Here, we demonstrate that a polytriarylamine, poly[N,N '-bis(4-butylphenyl)-N,N '-bis(phenyl)benzidine] (PolyTPD), can absorb almost full range of SWIR wavelength (lambda = 1000-3200 nm) after 48 h doping with tris(pentafluorophenyl)borane (BCF). The spectroscopic characterization disclosed that an electron transfer from PolyTPD to BCF created a new low energy level (gap) state leading to the SWIR absorption in the BCF-doped PolyTPD complexes. Organic phototransistors (OPTRs) with the BCF-doped PolyTPD films as a gate-sensing layer could detect the SWIR light with a reasonable photoresponsivity of similar to 538 mA W-1 (lambda = 1500 nm), similar to 541 mA W-1 (lambda = 2000 nm), and similar to 222 mA W-1 (lambda = 3000 nm). The present breakthrough SWIR-OPTR technology can pave a way for further advances in SWIR-absorbing organic materials and flexible SWIR sensors. Lee, Chulyeon; Kim, Hwajeong; Kim, Youngkyoo Kyungpook Natl Univ, Sch Appl Chem Engn, Dept Chem Engn, Organ Nanoelect Lab, Daegu, South Korea; Kyungpook Natl Univ, Sch Appl Chem Engn, Dept Chem Engn, KNU Inst Nanophoton Applicat KINPA, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Environm Sci & Technol, Prior Res Ctr, Daegu, South Korea 56354831300; 15520531700; 10340424400 ykimm@knu.ac.kr; NPJ FLEXIBLE ELECTRONICS NPJ FLEX ELECTRON 2397-4621 5 1 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;MATERIALS SCIENCE, MULTIDISCIPLINARY 2021 12.019 3.8 1.53 2025-07-30 34 27 DONOR-ACCEPTOR POLYMERS; PHOTODETECTORS; POLARONS; DESIGN English 2021 2021-04-12 10.1038/s41528-021-00105-z 바로가기 바로가기 바로가기 바로가기
Article 1-Methylcyclopropene (1-MCP) treatment delays modification of cell wall pectin and fruit softening in "Hwangok" and "Picnic" apples during cold storage Despite an increase in the use of 1-methylcyclopropene (1-MCP) to delay fruit softening, the role of 1-MCP in the modification of cell wall pectin to maintain apple fruit firmness during storage is poorly understood. Hence, in this study, we investigated whether 1-MCP treatment delayed fruit softening through pectin modification, in "Hwangok" and "Picnic" apple cultivars, stored up to six months at 0 degrees C. In both cultivars, 1-MCP-treated apples maintained firmness and exhibited lower internal ethylene concentrations compared with untreated fruit. The depolymerization of pectin in all pectin fractions was attenuated in 1-MCP-treated fruit compared with untreated fruit. In addition, a peak location shift was observed in the molecular mass profile of untreated fruit. Neutral sugar contents (arabinose and galactose), which typically change as fruit ripen, were effectively maintained in 1MCP-treated fruit. The activity of four important enzymes involved in pectin modification (exo-polygalacturonase, pectin methylesterase, beta-galactosidase, and alpha-L-arabinofuranosidase) was reduced in treated fruit compared to the control. Furthermore, 1-MCP treatment reduced the expression of pectin-degrading candidate genes (MdPG1, MdPME1, Mdfl-GAL1, Mdfl-GAL2, and Md alpha-ARF2). This study suggests that 1-MCP maintains cell wall pectin and delays the softening of the two apple cultivars by reducing the solubilization of polyuronides and neutral sugars, and limiting the activities of cell wall hydrolysis. Win, Nay Myo; Yoo, Jingi; Naing, Aung Htay; Kwon, Jung-Geun; Kang, In-Kyu RDA, Natl Inst Hort & Herbal Sci, Apple Res Inst, Gunwi 39000, South Korea; Washington State Univ, Tree Fruit Res & Extens Ctr, Wenatchee, WA 98801 USA; Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea ; Naing, Aung Htay/AAF-4277-2019 42462548000; 56818324500; 37112768100; 57211404168; 56577308800 kangik@knu.ac.kr; POSTHARVEST BIOLOGY AND TECHNOLOGY POSTHARVEST BIOL TEC 0925-5214 1873-2356 180 SCIE AGRONOMY;FOOD SCIENCE & TECHNOLOGY;HORTICULTURE 2021 6.751 3.9 8.19 2025-07-30 96 100 Apple; Softening; 1-Methylcyclopropene; Pectin; Pectin-degrading enzymes; Cold storage MODIFYING ENZYMES; DEGRADING ENZYMES; METABOLISM; EXPRESSION; CULTIVARS; ETHYLENE; QUALITY; PEAR; POLYSACCHARIDES; MONOSACCHARIDES 1-Methylcyclopropene; Apple; Cold storage; Pectin; Pectin-degrading enzymes; Softening English 2021 2021-10 10.1016/j.postharvbio.2021.111599 바로가기 바로가기 바로가기 바로가기
Article An Adaptive Unscented Kalman Filter With Selective Scaling (AUKF-SS) for Overhead Cranes This article introduces an augmented adaptive unscented Kalman filter (KF). The proposed novel technique is suitable to simultaneously estimate both the diagonal process noise covariance matrix and the unknown inputs, thus combining previously reported KF estimators for unknown inputs (dual or joint KF) and for covariance matrices (adaptive KF). A selective scaling method is also introduced to improve the convergence property of the suggested KF. The development of the novel KF is also motivated by a specific estimation problem related to crane systems. Cranes represent a special class of weight handling equipment as they are underactuated and described by nonlinear dynamics such that the load present oscillatory behavior. In addition to the increasing need for their automation in various industrial fields, these features also make them a benchmark system in control engineering with numerous control laws reported in the literature for sway elimination and trajectory tracking. A common issue to realize most of the advanced control laws on real, eventually industrial size cranes is the necessity to know the sway angle and frictions on the configuration variables. It is shown in simulation and also with real experiments on a reduced size overhead crane system that the suggested KF is suitable to estimate both the sway angles and the frictions. Kim, Jaehoon; Lee, Dongik; Kiss, Balint; Kim, Donggil Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea; Budapest Univ Technol & Econ, Dept Control Engn & Informat Technol, H-1111 Budapest, Hungary; Kyungil Univ, Dept Robot Engn, Gyongsan 712701, South Korea Kim, Donggil/AAY-5032-2021; Kiss, Balint/H-3960-2012 57202767865; 55698910600; 16646213500; 23090866400 destiny-be@hanmail.net;dilee@ee.knu.ac.kr;bkiss@iit.bme.hu;dgkim@kiu.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 68 7 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2021 8.162 3.9 2.57 2025-07-30 39 46 Cranes; Covariance matrices; Kalman filters; Estimation; Friction; Adaptation models; Mathematical model; Adaptive Kalman filtering (KF); overhead crane; scaling factor; unknown input estimation ANTISWING CONTROL; TRACKING; SYSTEMS Adaptive Kalman filtering (KF); overhead crane; scaling factor; unknown input estimation Bridge cranes; Control theory; Covariance matrix; Friction; Gantry cranes; Kalman filters; Convergence properties; Covariance matrices; Estimation problem; Handling equipments; Oscillatory behaviors; Overhead crane system; Trajectory tracking; Unscented Kalman Filter; Adaptive filtering English 2021 2021-07 10.1109/tie.2020.2996150 바로가기 바로가기 바로가기 바로가기
Article Current-Fed Quasi-Z-Source Full-Bridge Isolated DC-DC Converter This article presents current-fed (CF) full-bridge (FB) isolated dc-dc converter using quasi-Z-source network. Owing to its inherent buck-boost and clamping function, the proposed converter can effectively eliminate start-up and switch voltage overshoot problems. In addition, when compared with the conventional CF-FB converter with active clamp, switch current stress is much reduced and less active switches are required. Operation principles of the proposed converter are analyzed in detail. The simulation and experimental results with 1-kW prototype are also provided to verify theoretical analysis. Nguyen, Tien-The; Cha, Honnyong; Kim, Heung-Geun Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Elect Engn, Daegu 41566, South Korea ; Nguyen, Tien/ABX-3214-2022 59454647000; 24450248400; 7410122126 nguyenthetien93@gmail.com;chahonny@knu.ac.kr;kimhg@knu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 68 12 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2021 8.162 3.9 0.61 2025-07-30 6 12 Switches; Inductors; DC-DC power converters; Clamps; Capacitors; Stress; Windings; Active clamp; buck-boost; current-fed (CF); dc-dc converter; isolated; quasi-z-source (qZS); reliability; start-up; voltage overshoot FRONT-END-CONVERTER; Z-SOURCE INVERTER; VOLTAGE Active clamp; buck-boost; current-fed (CF); dc-dc converter; isolated; quasi-z-source (qZS); reliability; start-up; voltage overshoot Voltage regulators; Active clamp; Active switches; Current fed; Current stress; Full bridge; Isolated dc-dc converters; Switch voltage; Z-source networks; DC-DC converters English 2021 2021-12 10.1109/tie.2020.3047008 바로가기 바로가기 바로가기 바로가기
Article Enhancement of the flower longevity of petunia by CRISPR/Cas9-mediated targeted editing of ethylene biosynthesis genes The transcriptional activation of genes that encode the ethylene biosynthesis enzyme 1-aminocyclopropane-1carboxylate oxidase (PhACO3 and PhACO4) during petunia flower senescence has been reported. However, no studies have elaborately investigated their specific roles in ethylene production and flower longevity using genetic manipulation. Hence, we used the CRISPR/Cas9 system to edit the genes (PhACO3 and/or PhACO4) involved in ethylene production and flower longevity in petunia cv. Mirage Rose. The use of the CRISPR/Cas9 system with a sgRNA, which was designed from exon 2 of PhACO3, allows for the specific editing of the genes PhACO3 and/or PhACO4 with high mutation frequency, consequently producing different types of zygotes. The PhACO3 and PhACO4-edited lines 8 and 9 showed remarkably reduced ethylene production (approximately 2.8 to 3.0-fold in corollas and 1.5-fold in pistils) during flowering and extended flower longevity (approximately 9.5 d), while the PhACO3-edited bi-allelic and PhACO4-edited homozygous T0 mutant lines (14 and 23) showed enhanced flower longevity (approximately 8.0 d) compared with 6.0 d for the WT line. This was associated with reduction of PhACO4 protein levels in PhACO4-edited lines, which was confirmed using Western blot analysis and Image J software. Moreover, there was no undesirable editing effect on the PhACO1 gene. The transmission of the edited alleles to the T1 generation was also observed, and ethylene production and flower longevity were identical to those of the T0 mutant lines. Taken together, this study demonstrated not only the single and combined role of PhACO3 and PhACO4 in ethylene production in petunia flowers but also reports improvements in flower longevity by editing of the aforementioned genes using the CRISPR/Cas9 system. Therefore, our study can pave the way for the editing of homologous genes in other ornamental plants using the CRISPR/Cas9 system with a common sgRNA, thus allowing for a timeand cost-effective approach to advancing plant biology and the floricultural industry. Xu, Junping; Naing, Aung Htay; Bunch, Heeyoun; Jeong, Jaehyeon; Kim, Hyeran; Kim, Chang Kil Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Kangwon Natl Univ, Dept Biol Sci, Chunchon 24341, South Korea ; Naing, Aung Htay/AAF-4277-2019; Bunch, Heeyoun/JAX-3215-2023 56677024300; 37112768100; 56336812200; 57218602696; 57203911179; 7409880701 ckkim@knu.ac.kr; POSTHARVEST BIOLOGY AND TECHNOLOGY POSTHARVEST BIOL TEC 0925-5214 1873-2356 174 SCIE AGRONOMY;FOOD SCIENCE & TECHNOLOGY;HORTICULTURE 2021 6.751 3.9 2.8 2025-07-30 26 31 Ethylene production; Floral organs; Genome editing; Mutant types Ethylene production; Floral organs; Genome editing; Mutant types; T<sub>1</sub> generation English 2021 2021-04 10.1016/j.postharvbio.2020.111460 바로가기 바로가기 바로가기 바로가기
Article Highly Efficient Bidirectional Current-Fed Resonant Converter Over a Wide Voltage Gain Range In this article, we propose a current-fed bidirectional resonant converter that has minimal switching loss over a wide voltage gain range. The proposed bidirectional resonant converter employs a double current-fed structure at the low-voltage side and an active voltage doubler with a bidirectional switch at the high-voltage side.The converter operates as a pulsewidth-modulation (PWM) double current-fed resonant converter in the forward mode and a PWM half-bridge resonant converter in the backward mode. By incorporating a bidirectional switch across center nodes of the active voltage doubler, the converter achieves almost zero-voltage switching at the turn-off instant, thereby, incurring little switching loss at all active switches. The proposed topology exhibits a high conversion ratio with low transformer turns-ratio and a low current ripple at the low-voltage side. The operating principles and theoretical derivations of the converter are discussed in detail. The performance of the proposed bidirectional converter are verified using a prototype that has 48-72-V low voltage, 380-V high voltage, and 1-kW output power. Kim, Nam-Gyeong; Jo, Seung-Won; Han, Byeongcheol; Choi, Han-Ho; Kim, Minsung Dongguk Univ Seoul, Div Elect & Elect Engn, Seoul 04620, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea ; Han, Byeongcheol/W-7608-2019 57220177838; 57217022071; 57188622752; 7404338793; 57201445330 wgx010@naver.com;vsw3127@naver.com;hbychol@knu.ac.kr;hhchoi@dongguk.edu;mkim@dgu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 68 11 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2021 8.162 3.9 0.74 2025-07-30 10 13 Switches; Pulse width modulation; Resonant converters; Capacitors; Low voltage; Zero voltage switching; Inductors; Bidirectional switch; input voltage variation; low current ripple; pulsewidth modulation (PWM); zero-voltage switching (ZVS) Bidirectional switch; input voltage variation; low current ripple; pulsewidth modulation (PWM); zero-voltage switching (ZVS) Gain measurement; Pulse width modulation; Zero voltage switching; Bidirectional converter (BDC); Bidirectional current; Bidirectional switch; High conversions; Low current ripples; Operating principles; Resonant converters; Theoretical derivations; Power converters English 2021 2021-11 10.1109/tie.2020.3032928 바로가기 바로가기 바로가기 바로가기
Review Machine learning for sperm selection Infertility rates and the number of couples seeking fertility care have increased worldwide over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are being performed globally every year, but the success rate has remained at similar to 33%. Machine learning, an automated method of data analysis based on patterns and inference, is increasingly being deployed within the health-care sector to improve diagnostics and therapeutics. This technique is already aiding embryo selection in some fertility clinics, and has also been applied in research laboratories to improve sperm analysis and selection. Tremendous opportunities exist for machine learning to advance male fertility treatments. The fundamental challenge of sperm selection - selecting the most promising candidate from 10(8) gametes - presents a challenge that is uniquely well-suited to the high-throughput capabilities of machine learning algorithms paired with modern data processing capabilities. You, Jae Bem; McCallum, Christopher; Wang, Yihe; Riordon, Jason; Nosrati, Reza; Sinton, David Univ Toronto, Dept Mech & Ind Engn, Toronto, ON, Canada; Monash Univ, Dept Mech & Aerosp Engn, Clayton, Vic, Australia; Kyungpook Natl Univ, Dept Chem Engn, Daegu, South Korea Sinton, David/B-3095-2009; You, Jae/C-6211-2019; You, Jae Bem/C-6211-2019; Nosrati, Reza/I-1357-2019 55619455300; 57207033296; 57481813800; 26423260400; 36606797300; 6603799389 sinton@mie.utoronto.ca; NATURE REVIEWS UROLOGY NAT REV UROL 1759-4812 1759-4820 18 7 SCIE UROLOGY & NEPHROLOGY 2021 16.43 3.9 2.73 2025-07-30 56 62 CHROMATIN-STRUCTURE ASSAY; ARTIFICIAL-INTELLIGENCE; DNA FRAGMENTATION; PREDICTIVE-VALUE; REPRODUCTIVE TECHNOLOGIES; STRICT CRITERIA; DISPERSION-TEST; SEMEN QUALITY; MORPHOLOGY; HEALTH Cell Shape; DNA Damage; Fertilization in Vitro; Humans; Infertility; Machine Learning; Male; Semen Analysis; Sperm Injections, Intracytoplasmic; Sperm Motility; Sperm Retrieval; Spermatozoa; data analysis; embryo; fertility clinic; gamete; health care cost; human; human cell; machine learning; male; male fertility; review; semen analysis; sperm selection; cell shape; cytology; DNA damage; in vitro fertilization; infertility; intracytoplasmic sperm injection; metabolism; procedures; sperm retrieval; spermatozoon; spermatozoon motility English 2021 2021-07 10.1038/s41585-021-00465-1 바로가기 바로가기 바로가기 바로가기
Article Novel Virtual-Ground Single-Stage Single-Inductor Transformerless Buck-Boost Inverter In this article, a novel single-phase single-stage transformerless inverter is proposed for grid-tied and standalone applications. The proposed inverter has low leakage current and can perform both buck and boost functions. Furthermore, compared to the conventional state-of-the-art buck-boost inverters, it can achieve high power density because the magnetic volume is reduced significantly. In addition, high power conversion efficiency can be realized because only one switch operates at a high frequency. Moreover, there is no need for inserting high-frequency dead-time between the switches because only one switch receives high frequency and all other switches receive line frequency signals. In order to verify the performance of the proposed topology, a laboratory prototype is designed for 500 W, and the experimental results are provided as well. Akbar, Fazal; Cha, Honnyong; Kim, Heung-Geun Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Elect Engn, Daegu 41566, South Korea akbar, fazal/AAU-7197-2020 57194409251; 24450248400; 7410122126 fazalakbar923@gmail.com;chahonny@knu.ac.kr;hgkim@knu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 68 8 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2021 8.162 3.9 0.81 2025-07-30 14 16 Switches; Inverters; Leakage currents; Capacitors; Inductors; Topology; High frequency; Inductor; power density; pulsewidth modulation (PWM); virtual-ground; voltage-source inverter (VSI) POWER POINT TRACKING; CONVERTER; DC Inductor; power density; pulsewidth modulation (PWM); virtual-ground; voltage-source inverter (VSI) Conversion efficiency; Electric autotransformers; Leakage currents; Switching frequency; Time switches; Buck boost inverter; High frequency HF; High power conversion; High power density; Low-leakage current; Standalone applications; State of the art; Transformerless inverters; Electric inverters English 2021 2021-08 10.1109/tie.2020.3007117 바로가기 바로가기 바로가기 바로가기
Article Split-Capacitor Dual-Active-Bridge Converter In this article, a split-capacitor (SC) dual-active-bridge (DAB) converter is proposed. In the proposed converter, dc-link capacitors in both the input and output are split, and primary and secondary windings of the transformer are connected to midpoints of the input and output dc links, respectively. Although the switch current stress of the proposed converter is twice that of conventional DAB converter, its switch voltage stress is reduced to half. Therefore, the proposed converter has higher conduction loss than the conventional DAB converter, however, the switching loss can be reduced, which implies that the proposed converter is beneficial and can achieve higher efficiency than the conventional DAB converter as switching frequency increases. In addition, owing to the SC structure, no dc-blocking capacitors are required and the proposed converter can be readily connected to neutral-point-clamped or half-bridge-type converters without increasing the number of dc-link capacitors. To verify the performances of the proposed converter, 3-kW prototypes are built, tested, and compared. Kim, Kisu; Cha, Honnyong Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea ; Kim, Kisu/LBH-7363-2024 57195371307; 24450248400 kimkisu1027@gmail.com;chahonny@knu.ac.kr; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 68 2 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2021 8.162 3.9 1.28 2025-07-30 17 21 Bidirectional converter; dc blocking capacitor; dual-active-bridge; split-capacitor; zero-voltage switching DC-DC CONVERTER; SYSTEMS Bidirectional converter; dc-blocking capacitor; dual active bridge (DAB); split capacitor (SC); zero-voltage switching (ZVS) DC transformers; Switching frequency; Transformer windings; Blocking capacitor; Dc link capacitor; Dual active bridge converter; Dual active bridges; Higher efficiency; Input and outputs; Neutral point clamped; Secondary windings; Power converters English 2021 2021-02 10.1109/tie.2020.2969118 바로가기 바로가기 바로가기 바로가기
Article Switching-Cell Four-Leg Current Source Inverter Conventional current source inverter (CSI) suffers from open-circuit problem during switch transition. Thus, overlap-time should be inserted in the gate signals for safe commutation. The overlap-time distorts output current waveforms and increases total harmonic distortion of output current. Moreover, it reduces the current source utilization of the inverter. To solve these problems, this article proposes a new three-phase four-leg switching-cell (SC) CSI, abbreviated as H8-SC-CSI. With the help of the SC structure, the reliability of the proposed inverter is greatly enhanced as open-circuit concerns are eliminated. In addition, with the intrinsic voltage clamping action of the SC structure, switch voltage overshoot at turn-OFF is mitigated. In the proposed CSI, the switch overlap-time can be minimized or eliminated because the inductor current can flow through the SC capacitors. A 1.2 kW prototype inverter is designed and tested to verify the feasibility of the circuit. Duc-Tuan Do; Cha, Honnyong; Akbar, Fazal Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea akbar, fazal/AAU-7197-2020; Do, Duc Tuan/ISB-5137-2023 57202470961; 24450248400; 57194409251 doductuan-tdh@tnut.edu.vn;chahonny@knu.ac.kr;fazalakbar923@gmail.com; IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS IEEE T IND ELECTRON 0278-0046 1557-9948 68 11 SCIE AUTOMATION & CONTROL SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION 2021 8.162 3.9 0.95 2025-07-30 14 16 Total harmonic distortion; Motor drives; Commutation; Prototypes; Switches; Logic gates; Inverters; Current source inverter (CSI); four-leg inverter; high reliability; overlap-time; switching-cell (SC); three-phase inverter; voltage overshoot RELIABILITY; MODULATION; CONVERTERS Current source inverter (CSI); four-leg inverter; high reliability; overlap-time; switching-cell (SC); three-phase inverter; voltage overshoot Voltage regulators; Conventional currents; Current source inverter; Inductor currents; Safe commutations; Switch transition; Three-phase four-leg; Total harmonic distortion (THD); Voltage clamping; Electric inverters English 2021 2021-11 10.1109/tie.2020.3036229 바로가기 바로가기 바로가기 바로가기
Article Association of Physical Activity and APOE Genotype With Longitudinal Cognitive Change in Early Parkinson Disease Objective To determine whether greater physical activity could modify the negative association of APOE epsilon 4 with longitudinal cognitive changes in early Parkinson disease (PD) and to uncover the disease-specific mechanism for explaining such benefits of physical activity. Methods We used data from the Parkinson's Progression Markers Initiative cohort. Because self-reported physical activity, measured by the Physical Activity Scale of the Elderly, was initiated at 2 years after enrollment, this longitudinal analysis was based on assessments performed at years 2, 3, and 4. Cognitive function was measured annually with the Montreal Cognitive Assessment (MoCA). Dopamine transporter (DAT) imaging was performed at years 2 and 4. We assessed the interactive associations between physical activity and the APOE epsilon 4 allele on the longitudinal changes in MoCA scores and striatal DAT activities. Results A total of 173 patients with early PD (age 63.3 +/- 10.0 years, 27% APOE epsilon 4 carriers) were included. The APOE epsilon 4 allele showed a steeper rate of cognitive decline than the non-APOE epsilon 4 allele (estimate -1.33, 95% confidence interval [CI] -2.12 to -0.47, p = 0.002). However, there was a significant interaction between physical activity and APOE epsilon 4 such that higher physical activity was related to slower APOE epsilon 4-related cognitive decline (estimate 0.007, 95% CI 0.003-0.011, p = 0.001). No significant interaction was found between physical activity and the APOE epsilon 4 allele regarding the change in striatal DAT activities. Conclusion Increased physical activity attenuated APOE epsilon 4-related vulnerability to early cognitive decline in patients with PD. This protective effect did not appear to be mediated by striatal dopaminergic function. Classification of Evidence This study provides Class II evidence that increased physical activity was associated with decreased APOE epsilon 4-related early cognitive decline in patients with PD. Kim, Ryul; Park, Sangmin; Yoo, Dallah; Jun, Jin-Sun; Jeon, Beomseok Inha Univ Hosp, Dept Neurol, Incheon, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Daegu, South Korea; Kyung Hee Univ Hosp, Dept Neurol, Seoul, South Korea; Hallym Univ, Coll Med, Kangnam Sacred Heart Hosp, Dept Neurol, Chunchon, South Korea; Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea ; Yoo, Dallah/ABB-6365-2021 56591470700; 57197524938; 57202011449; 56523978900; 7102161956 junjs@hallym.or.kr; NEUROLOGY NEUROLOGY 0028-3878 1526-632X 96 19 SCIE CLINICAL NEUROLOGY 2021 12.258 4.0 1.52 2025-07-30 15 18 QUALITY-OF-LIFE; ALPHA-SYNUCLEIN; ALZHEIMERS-DISEASE; ACTIVITY SCALE; ELDERLY PASE; EXERCISE; IMPAIRMENT; BIOMARKERS; INCIDENT; INSTRUMENTS Aged; Apolipoprotein E4; Cognitive Dysfunction; Cohort Studies; Exercise; Female; Genotype; Humans; Longitudinal Studies; Male; Middle Aged; Parkinson Disease; apolipoprotein E4; aged; clinical trial; cognitive defect; cohort analysis; exercise; female; genetics; genotype; human; longitudinal study; male; middle aged; multicenter study; Parkinson disease; physiology; psychology English 2021 2021-05-11 10.1212/wnl.0000000000011852 바로가기 바로가기 바로가기 바로가기
Article Design and performance analysis of an airborne wind turbine for high-altitude energy harvesting The airborne wind turbine (AWT) offers the opportunity to be installed in challenging heights. For this purpose, the present study focuses on the aerodynamic design of an airborne rotor lifted to high altitude from the viewpoint of airborne technology. The rotor blade is modeled by imposing the elevated wind dataset while the outer shape is comprised of multi-profiles of thick airfoils. Numerical approaches of the BEM and RANS-CFD are employed for insight into performance analysis. The extracted results of the CFD data agreed well with the empirical computations. The induced effect of the diffuser on the rotor is demonstrated through an auxiliary shell structure. A range of 3D simulations varying the airloads are conducted to investigate the on-design and off-design behavior of the rotor. The power coefficient (C-p), effective forces and mass amplification are computed and discussed in terms of performance indicators. The design analysis reveals the significance of the chosen design specification to an operational height of 400 m. The noticeable finding confirms that the optimal C-p of the resulting rotor always occurs at rated conditions and equally valid for both configurations. Additionally, a power gain of 21.3% is obtained from the rotor equipped with the diffuser geometry. (C) 2021 Elsevier Ltd. All rights reserved. Ali, Qazi Shahzad; Kim, Man-Hoe Kyungpook Natl Univ, Sch Mech Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, IEDT, Daegu 41566, South Korea 57209058973; 55686310000 shahzad@knu.ac.kr;manhoe.kim@knu.ac.kr; ENERGY ENERGY 0360-5442 1873-6785 230 SCIE ENERGY & FUELS;THERMODYNAMICS 2021 8.857 4.0 1.42 2025-07-30 21 23 Airborne wind turbine; Wind turbine design; High altitude wind energy; Steady aerodynamic performance; Airborne wind energy; Renewable energy AERODYNAMIC PERFORMANCE; SYSTEMS Airborne wind energy; Airborne wind turbine; High altitude wind energy; Renewable energy; Steady aerodynamic performance; Wind turbine design Aerodynamics; Computational fluid dynamics; Energy harvesting; Wind turbines; Aerodynamic designs; Airborne wind energy; Airborne wind turbine; Design Analysis; Energy; High altitude wind energy; Performances analysis; Renewable energies; Steady aerodynamic performance; Wind turbine design; aerodynamics; data set; empirical analysis; instrumentation; numerical model; performance assessment; wind turbine; Wind power English 2021 2021-09-01 10.1016/j.energy.2021.120829 바로가기 바로가기 바로가기 바로가기
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